Probiotic potential risk score
| ARGs | VFs | PGs | PPRS |
|---|---|---|---|
| 0 | 26 | 28 | 38.21 |
PPRS is classified as low-risk (≤4), medium-risk (4-6), and high-risk (≥6).
Antibiotic resistance genes
Comprehensive Antibiotic Resistance Database (CARD)
| Query ID | Begin | End | ARO name | ARO accession | CARD name | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
RGI v6.0.3 (Database: CARD Variants v4.0.2, Nov. 2023 release)
ResFinder
| Query ID | Begin | End | Resistance gene | Phenotype | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|
| No hit found | |||||||
ResFinder v4.6.0 (Database: resfinder_db, Aug. 2024 release)
AMRFinderPlus
| Query ID | Begin | End | Gene symbol | Sequence name | Method | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
AMRFinderPlus v4.0.3 (Database: Oct. 2024 release)
Virulence factors
Virulence Factor Database (VFDB)
| Query ID | qstart | qend | Gene name | e-value | VF name | VF category | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|---|
| MAPGIKHE_1 | 1335700 | 1336509 | STU_RS16245 | 0.0 | Capsule | Immune modulation | 99.88 | 100.00 | WP_002948020 |
| MAPGIKHE_1 | 1336493 | 1337449 | STU_RS16250 | 0.0 | Capsule | Immune modulation | 99.79 | 100.00 | WP_011226328 |
| MAPGIKHE_1 | 1337446 | 1338594 | STU_RS16255 | 0.0 | Capsule | Immune modulation | 99.74 | 100.00 | WP_041828290 |
| MAPGIKHE_1 | 860765 | 862423 | fbp54 | 0.0 | FBPs | Adherence | 99.64 | 100.00 | WP_011227179 |
| MAPGIKHE_1 | 1333420 | 1334475 | STU_RS16235 | 0.0 | Capsule | Immune modulation | 99.62 | 100.00 | WP_002948022 |
| MAPGIKHE_1 | 1331639 | 1333423 | STU_RS16230 | 0.0 | Capsule | Immune modulation | 99.61 | 100.00 | WP_011226325 |
| MAPGIKHE_1 | 982891 | 983490 | STR_RS05245 | 0.0 | Capsule | Immune modulation | 99.50 | 100.00 | WP_196767671 |
| MAPGIKHE_1 | 48232 | 49071 | cbpD | 0.0 | Autolysin | Exoenzyme | 99.41 | 100.00 | WP_011226733 |
| MAPGIKHE_1 | 1334495 | 1335700 | STU_RS16240 | 0.0 | Capsule | Immune modulation | 99.25 | 100.00 | WP_011226326 |
| MAPGIKHE_1 | 1111461 | 1112054 | STR_RS05880 | 0.0 | Capsule | Immune modulation | 99.16 | 100.00 | WP_011226149 |
| MAPGIKHE_1 | 962225 | 963640 | STER_RS05250 | 0.0 | Capsule | Immune modulation | 99.15 | 100.00 | WP_011681165 |
| MAPGIKHE_1 | 1112054 | 1112923 | rfbA | 0.0 | Capsule | Immune modulation | 99.08 | 100.00 | WP_011681286 |
| MAPGIKHE_1 | 1149057 | 1149818 | srtA | 0.0 | Sortase A | Exoenzyme | 99.08 | 100.00 | - |
| MAPGIKHE_1 | 1111461 | 1112054 | STER_RS06030 | 0.0 | Capsule | Immune modulation | 98.99 | 100.00 | WP_011226149 |
| MAPGIKHE_1 | 1111461 | 1112054 | STU_RS15260 | 0.0 | Capsule | Immune modulation | 98.99 | 100.00 | WP_011226149 |
| MAPGIKHE_1 | 985820 | 987274 | STR_RS05265 | 0.0 | Capsule | Immune modulation | 98.83 | 100.00 | WP_041827043 |
| MAPGIKHE_1 | 1341253 | 1342527 | STU_RS16265 | 0.0 | Capsule | Immune modulation | 98.82 | 100.00 | WP_011226331 |
| MAPGIKHE_1 | 985088 | 985819 | STER_RS05315 | 0.0 | Capsule | Immune modulation | 98.77 | 100.00 | WP_011681176 |
| MAPGIKHE_1 | 1053810 | 1054600 | cshA | 0.0 | Cell surface hydrophobicity proteins | Adherence | 98.74 | 100.00 | - |
| MAPGIKHE_1 | 1340291 | 1341253 | STU_RS16260 | 0.0 | Capsule | Immune modulation | 98.55 | 95.25 | WP_011226330 |
| MAPGIKHE_1 | 981767 | 982726 | STR_RS05240 | 0.0 | Capsule | Immune modulation | 98.54 | 100.00 | WP_041827042 |
| MAPGIKHE_1 | 985088 | 985819 | STU_RS14645 | 0.0 | Capsule | Immune modulation | 98.50 | 100.00 | WP_011226048 |
| MAPGIKHE_1 | 985088 | 985819 | STR_RS05260 | 0.0 | Capsule | Immune modulation | 98.36 | 100.00 | WP_011227248 |
| MAPGIKHE_1 | 985820 | 987274 | STU_RS14650 | 0.0 | Capsule | Immune modulation | 98.28 | 100.00 | WP_011226049 |
| MAPGIKHE_1 | 983642 | 984377 | STER_RS05305 | 0.0 | Capsule | Immune modulation | 97.01 | 99.33 | WP_011681174 |
| MAPGIKHE_1 | 985820 | 987274 | STER_RS05320 | 0.0 | Capsule | Immune modulation | 96.72 | 99.79 | WP_011681177 |
| MAPGIKHE_1 | 983628 | 984377 | STR_RS05250 | 0.0 | Capsule | Immune modulation | 96.40 | 100.00 | WP_011227246 |
| MAPGIKHE_1 | 1343628 | 1344479 | rfbD | 0.0 | Capsule | Immune modulation | 96.13 | 100.00 | WP_014621820 |
| MAPGIKHE_1 | 983642 | 984377 | STU_RS14635 | 0.0 | Capsule | Immune modulation | 95.92 | 99.33 | WP_011226046 |
| MAPGIKHE_1 | 984387 | 985079 | STER_RS05310 | 0.0 | Capsule | Immune modulation | 89.61 | 100.00 | WP_011681175 |
| MAPGIKHE_1 | 984387 | 985079 | STU_RS14640 | 0.0 | Capsule | Immune modulation | 89.47 | 100.00 | WP_011226047 |
| MAPGIKHE_1 | 984387 | 985079 | STR_RS05255 | 0.0 | Capsule | Immune modulation | 89.18 | 100.00 | WP_011227247 |
| MAPGIKHE_1 | 593822 | 595125 | eno | 0.0 | Streptococcal enolase | Exoenzyme | 87.95 | 99.46 | WP_000022832 |
| MAPGIKHE_1 | 1629993 | 1631003 | plr/gapA | 0.0 | Streptococcal plasmin receptor/GAPDH | Adherence | 86.43 | 99.51 | WP_002986042 |
| MAPGIKHE_1 | 142575 | 143858 | tig/ropA | 0.0 | Trigger factor | Stress survival | 80.81 | 99.77 | WP_000107753 |
| MAPGIKHE_1 | 1109985 | 1111031 | rfbB | 0.0 | Capsule | Immune modulation | 80.61 | 100.00 | WP_009659423 |
BLASTN v2.16.0 (Database: VFDB, Dec. 2024 release)
VirulenceFinder
| Query ID | Begin | End | Database | Virulence factor | Protein function | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
VirulenceFinder v2.0. 4 (Database: virulencefinder_db, Feb . 2024 release)
Pathogenic genes
PHI-base
| Query ID | qstart | qend | Gene name | e-value | Function | Identity | Coverage | Gene ID |
|---|---|---|---|---|---|---|---|---|
| MAPGIKHE_1 | 1152505 | 1153488 | ldh(Sp_1220) | 0.0 | L-lactate dehydrogenase | 94.82 | 100.00 | AAK75326 |
| MAPGIKHE_1 | 713682 | 714755 | MntE | 0.0 | manganese homeostasis | 94.41 | 99.72 | ABF32167 |
| MAPGIKHE_1 | 1508427 | 1510730 | pfl2(Sp_0459) | 0.0 | formate acetyltransferase | 93.23 | 99.22 | AAK74619 |
| MAPGIKHE_1 | 509459 | 510427 | spr0084 | 0.0 | pathogenitcity related | 93.19 | 98.48 | AAK98888 |
| MAPGIKHE_1 | 1243137 | 1244618 | SPD_0310 | 0.0 | UPF0371 protein SPD_0310 | 92.92 | 100.00 | ABJ54480 |
| MAPGIKHE_1 | 736847 | 739093 | metE | 0.0 | methionine biosynthesis enzymes | 91.99 | 100.00 | AAK74738 |
| MAPGIKHE_1 | 67863 | 68861 | recA | 0.0 | DNA recombination and repair | 91.29 | 85.82 | AAL00560 |
| MAPGIKHE_1 | 31749 | 32720 | prsA2 | 0.0 | ribose-phosphate pyrophosphokinase | 90.12 | 100.00 | ABF36968 |
| MAPGIKHE_1 | 1388000 | 1386849 | potA | 0.0 | ABC transporter ATP-binding protein-spermidine/putrescine transport | 89.32 | 99.74 | AAL00050 |
| MAPGIKHE_1 | 1357696 | 1355708 | uvrB | 0.0 | excinuclease ABC, B subunit | 88.99 | 100.00 | AE014259_2 |
| MAPGIKHE_1 | 1136308 | 1134578 | ptsI | 0.0 | phosphoenolpyruvate-protein phosphotransferase | 88.22 | 100.00 | AAK34199 |
| MAPGIKHE_1 | 1843057 | 1841579 | IMPDH | 0.0 | inosine-5'-monophosphate dehydrogenase | 87.83 | 100.00 | ADE32434 |
| MAPGIKHE_1 | 593822 | 595123 | Eno | 0.0 | enolase | 86.21 | 99.77 | ABP90468 |
| MAPGIKHE_1 | 1828320 | 1826428 | gidA | 0.0 | tRNA uridine 5-carboxymethylaminomethyl modification enzyme | 85.74 | 98.90 | ABP91129 |
| MAPGIKHE_1 | 744254 | 742545 | PGM | 0.0 | phosphoglucomutase | 83.71 | 99.65 | ACH87041 |
| MAPGIKHE_1 | 1672992 | 1674002 | pdh | 0.0 | pyruvate dehydrogenase | 83.09 | 99.70 | ABP91006 |
| MAPGIKHE_1 | 888640 | 887279 | mnmE | 0.0 | central tRNA-modifying GTPase | 82.02 | 99.56 | ABP90420 |
| MAPGIKHE_1 | 1725542 | 1723650 | PepO | 0.0 | endopeptidase | 80.03 | 100.00 | ABF32980 |
| MAPGIKHE_1 | 577145 | 578035 | bglB | 1.33e-178 | putative phospho--glucosidase | 88.89 | 99.66 | AAK33487 |
| MAPGIKHE_1 | 799942 | 799007 | SP_0676 | 7.39e-168 | transcription facot | 81.73 | 96.89 | AAK74821 |
| MAPGIKHE_1 | 739285 | 740142 | metF | 8.65e-165 | methionine biosynthesis enzymes | 86.36 | 99.31 | AAK74739 |
| MAPGIKHE_1 | 1026128 | 1025424 | covR | 4.38e-131 | responder protein | 85.53 | 100.00 | AAK71319 |
| MAPGIKHE_1 | 1209843 | 1209172 | rr01 | 2.83e-123 | response regulator | 83.48 | 99.56 | CAB54566 |
| MAPGIKHE_1 | 1026128 | 1025424 | walR | 1.85e-121 | DNA-binding response regulator | 82.13 | 100.00 | ANC99504 |
| MAPGIKHE_1 | 294349 | 295035 | CovR | 1.01e-117 | serves to repress GAS virulence factor-encoding genes | 80.79 | 100.00 | ACE75886 |
| MAPGIKHE_1 | 69137 | 69529 | SpxA2 | 5.27e-73 | transcriptional regulator | 90.08 | 99.24 | ERL21461 |
| MAPGIKHE_1 | 900119 | 900520 | SpxA1 | 3.76e-66 | transcriptional regulator | 80.60 | 100.00 | ERL19273 |
| MAPGIKHE_1 | 144016 | 144516 | RopE (M5005_Spy_1611) | 4.92e-75 | probable DNA-directed RNA polymerase subunit delta | 81.44 | 87.43 | AAK34603 |
| MAPGIKHE_1 | 1508427 | 1510724 | PFL (B9H01_RS01125) | 0.0 | formate C-acetyltransferase | 83.07 | 98.08 | MYN69560 |
| MAPGIKHE_1 | 1711087 | 1710068 | ilvC (SPD_0406) | 0.0 | ketol-acid reductoisomerase (NADP(+)) | 96.47 | 100.00 | ABJ55451 |
BLASTX v2.16.0 (Database: PHI base v4.16, May. 2024 release)
Plasmid
PlasmidFinder
| Query ID | Begin | End | Plasmid | Query / Template | Identity | Accession no. |
|---|---|---|---|---|---|---|
| No hit found | ||||||
PlasmidFinder v 2.1.6 (Database: plasmidfinder_db v 2.2.0 , Nov. 2024 release)
PlasmidHunter
| Query ID | Prediction | Chromosome | Plasmid |
|---|---|---|---|
| MAPGIKHE_1 | 0.0 | 1.0 | 0.0 |
PlasmidHunter v 1.4.5 (Database: May. 2024 release)
Prophage
Phigaro
| Query ID | Begin | End | Transposable | Taxonomy | pVOGs |
|---|---|---|---|---|---|
| No hit found | |||||
Phigaro v2.4.0 (Database: Jan. 2024 release)