Probiotic potential risk score
| ARGs | VFs | PGs | PPRS |
|---|---|---|---|
| 6 | 0 | 0 | 6.00 |
PPRS is classified as low-risk (≤4), medium-risk (4-6), and high-risk (≥6).
Antibiotic resistance genes
Comprehensive Antibiotic Resistance Database (CARD)
| Query ID | Begin | End | ARO name | ARO accession | CARD name | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| NLDOMKLD_4 | 3817515 | 3818405 | CblA-1 | ARO:3002999 | CblA-1 | 98.65 | 100.00 | GQ343019.1 |
| NLDOMKLD_4 | 3142308 | 3142838 | SAT-4 | ARO:3002897 | SAT-4 | 99.43 | 97.78 | U01945.1 |
| NLDOMKLD_4 | 3141421 | 3142216 | APH(3')-IIIa | ARO:3002647 | APH(3')-IIIa | 100.00 | 98.86 | CP004067.1 |
| NLDOMKLD_4 | 3137454 | 3138191 | ErmB | ARO:3000375 | ErmB | 97.96 | 98.79 | AF242872.1 |
| NLDOMKLD_4 | 2794003 | 2795928 | tet(Q) | ARO:3000191 | tet(Q) | 96.41 | 97.56 | Z21523.1 |
RGI v6.0.3 (Database: CARD Variants v4.0.2, Nov. 2023 release)
ResFinder
| Query ID | Begin | End | Resistance gene | Phenotype | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|
| NLDOMKLD_4 | 3141421 | 3142215 | aph(3')-III | Kanamycin, Amikacin, Neomycin, Butirosin, Isepamicin, Lividomycin, Paromomycin, Ribostamycin | 100.00 | 100.00 | M26832 |
| NLDOMKLD_4 | 2794003 | 2795928 | tet(Q) | Doxycycline, Tetracycline, Minocycline | 99.84 | 100.00 | L33696 |
| NLDOMKLD_4 | 3137454 | 3138191 | erm(B) | Erythromycin, Lincomycin, Clindamycin, Quinupristin, Pristinamycin IA, Virginiamycin S | 99.73 | 100.00 | U18931 |
| NLDOMKLD_4 | 4365013 | 4365966 | cfxA3 | Ampicillin | 85.95 | 98.65 | AF472622 |
| NLDOMKLD_4 | 4365013 | 4365966 | cfxA4 | Unknown Beta-lactam | 85.95 | 98.65 | AY769933 |
| NLDOMKLD_4 | 4365013 | 4365966 | cfxA5 | Unknown Beta-lactam | 85.95 | 98.65 | AY769934 |
| NLDOMKLD_4 | 4365013 | 4365966 | cfxA | Cefoxitin, Ampicillin | 85.95 | 98.65 | U38243 |
ResFinder v4.6.0 (Database: resfinder_db, Aug. 2024 release)
AMRFinderPlus
| Query ID | Begin | End | Gene symbol | Sequence name | Method | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| NLDOMKLD_4 | 3141424 | 3142215 | aph(3')-IIIa | aminoglycoside O-phosphotransferase APH(3')-IIIa | EXACTX | 100.00 | 100.00 | WP_001096887.1 |
| NLDOMKLD_4 | 3142311 | 3142850 | sat4 | streptothricin N-acetyltransferase Sat4 | EXACTX | 100.00 | 100.00 | WP_000627290.1 |
| NLDOMKLD_4 | 2794006 | 2795928 | tet(Q) | tetracycline resistance ribosomal protection protein Tet(Q) | BLASTX | 99.53 | 100.00 | WP_063856407.1 |
| NLDOMKLD_4 | 3137457 | 3138191 | erm(B) | 23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(B) | BLASTX | 99.18 | 100.00 | WP_002292226.1 |
| NLDOMKLD_4 | 3817515 | 3818402 | cblA | CblA family class A beta-lactamase | BLASTX | 98.65 | 100.00 | WP_005827792.1 |
| NLDOMKLD_4 | 4365012 | 4365962 | cfxA | CfxA family broad-spectrum class A beta-lactamase | BLASTX | 83.60 | 98.75 | WP_004339683.1 |
AMRFinderPlus v4.0.3 (Database: Oct. 2024 release)
Virulence factors
Virulence Factor Database (VFDB)
| Query ID | qstart | qend | Gene name | e-value | VF name | VF category | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|---|
| No hit found | |||||||||
BLASTN v2.16.0 (Database: VFDB, Dec. 2024 release)
VirulenceFinder
| Query ID | Begin | End | Database | Virulence factor | Protein function | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
VirulenceFinder v2.0. 4 (Database: virulencefinder_db, Feb . 2024 release)
Pathogenic genes
PHI-base
| Query ID | qstart | qend | Gene name | e-value | Function | Identity | Coverage | Gene ID |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
BLASTX v2.16.0 (Database: PHI base v4.16, May. 2024 release)
Plasmid
PlasmidFinder
| Query ID | Begin | End | Plasmid | Query / Template | Identity | Accession no. |
|---|---|---|---|---|---|---|
| No hit found | ||||||
PlasmidFinder v 2.1.6 (Database: plasmidfinder_db v 2.2.0 , Nov. 2024 release)
PlasmidHunter
| Query ID | Prediction | Chromosome | Plasmid |
|---|---|---|---|
| NLDOMKLD_1 | 1.0 | 0.0 | 1.0 |
| NLDOMKLD_2 | 1.0 | 0.0 | 1.0 |
| NLDOMKLD_3 | 1.0 | 0.0 | 1.0 |
| NLDOMKLD_4 | 0.0 | 1.0 | 0.0 |
| NLDOMKLD_5 | 0.0 | 1.0 | 0.0 |
| NLDOMKLD_6 | 1.0 | 0.0 | 1.0 |
PlasmidHunter v 1.4.5 (Database: May. 2024 release)
Prophage
Phigaro
| Query ID | Begin | End | Transposable | Taxonomy | pVOGs |
|---|---|---|---|---|---|
| NLDOMKLD_4 | 1981913 | 1992788 | False | Siphoviridae | VOG3992, |
| NLDOMKLD_4 | 2820259 | 2832104 | False | Siphoviridae | VOG3992, |
| NLDOMKLD_4 | 3633122 | 3643833 | False | Unknown | VOG5821, |
Phigaro v2.4.0 (Database: Jan. 2024 release)