Probiotic potential risk score
| ARGs | VFs | PGs | PPRS |
|---|---|---|---|
| 9 | 10 | 4 | 14.04 |
PPRS is classified as low-risk (≤4), medium-risk (4-6), and high-risk (≥6).
Antibiotic resistance genes
Comprehensive Antibiotic Resistance Database (CARD)
| Query ID | Begin | End | ARO name | ARO accession | CARD name | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| OGLDHGEA_1 | 2537328 | 2538530 | blt | ARO:3003006 | blt | 99.25 | 100.00 | L32599.1 |
| OGLDHGEA_1 | 1466548 | 1466865 | ykkD | ARO:3003064 | ykkD | 98.10 | 100.00 | AL009126.1 |
| OGLDHGEA_1 | 1466210 | 1466548 | ykkC | ARO:3003063 | ykkC | 99.11 | 100.00 | AL009126.1 |
| OGLDHGEA_1 | 913796 | 916366 | Bacillus subtilis mprF | ARO:3003324 | Bsub_mprF | 99.65 | 100.00 | AL009126.3 |
| OGLDHGEA_1 | 610727 | 612373 | vmlR | ARO:3004476 | vmlR | 98.36 | 100.18 | NC_000964.3 |
| OGLDHGEA_1 | 282872 | 284305 | lmrB | ARO:3002813 | lmrB | 98.95 | 100.00 | JYFL01000006.1 |
| OGLDHGEA_1 | 270058 | 270978 | mphK | ARO:3004541 | mphK | 98.68 | 100.00 | CP010314.1 |
RGI v6.0.3 (Database: CARD Variants v4.0.2, Nov. 2023 release)
ResFinder
| Query ID | Begin | End | Resistance gene | Phenotype | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|
| OGLDHGEA_1 | 4085730 | 4087106 | tet(L) | Doxycycline, Tetracycline, Doxycycline, Tetracycline, Minocycline, Tigecycline | 99.13 | 100.00 | D12567 |
| OGLDHGEA_1 | 270058 | 270978 | mph(K) | Spiramycin, Telithromycin | 98.05 | 100.00 | NC_000964 |
ResFinder v4.6.0 (Database: resfinder_db, Aug. 2024 release)
AMRFinderPlus
| Query ID | Begin | End | Gene symbol | Sequence name | Method | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| OGLDHGEA_1 | 4085733 | 4087106 | tet(L) | tetracycline efflux MFS transporter Tet(L) | BLASTX | 99.13 | 100.00 | WP_063856081.1 |
| OGLDHGEA_1 | 270058 | 270966 | mphK | macrolide 2'-phosphotransferase MphK | BLASTX | 98.68 | 99.02 | WP_003246254.1 |
| OGLDHGEA_1 | 610730 | 612373 | vmlR | ABC-F type ribosomal protection protein VmlR | BLASTX | 98.36 | 100.00 | WP_003234144.1 |
| OGLDHGEA_1 | 4083210 | 4083728 | satA | streptothricin N-acetyltransferase SatA | BLASTX | 90.75 | 100.00 | WP_003242546.1 |
AMRFinderPlus v4.0.3 (Database: Oct. 2024 release)
Virulence factors
Virulence Factor Database (VFDB)
| Query ID | qstart | qend | Gene name | e-value | VF name | VF category | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|---|
| OGLDHGEA_1 | 3581332 | 3582513 | capB | 0.0 | Capsule | Immune modulation | 99.66 | 100.00 | NP_391471 |
| OGLDHGEA_1 | 3088299 | 3089084 | dhbA | 0.0 | Bacillibactin | Nutritional/Metabolic factor | 99.62 | 100.00 | NP_391080 |
| OGLDHGEA_1 | 3579707 | 3580849 | capA | 0.0 | Capsule | Immune modulation | 99.30 | 100.00 | NP_391469 |
| OGLDHGEA_1 | 3084463 | 3085401 | dhbB | 0.0 | Bacillibactin | Nutritional/Metabolic factor | 99.15 | 100.00 | NP_391077 |
| OGLDHGEA_1 | 2022638 | 2024401 | dep/capD | 0.0 | Capsule | Immune modulation | 98.98 | 100.00 | NP_389723 |
| OGLDHGEA_1 | 2141867 | 2142508 | hlyIII | 0.0 | Hemolysin III | Exotoxin | 98.91 | 100.00 | NP_390062 |
| OGLDHGEA_1 | 3580868 | 3581317 | capC | 0.0 | Capsule | Immune modulation | 98.89 | 100.00 | NP_391470 |
| OGLDHGEA_1 | 3077307 | 3084443 | dhbF | 0.0 | Bacillibactin | Nutritional/Metabolic factor | 98.61 | 100.00 | NP_391076 |
| OGLDHGEA_1 | 3087077 | 3088273 | dhbC | 0.0 | Bacillibactin | Nutritional/Metabolic factor | 97.83 | 100.00 | NP_391079 |
| OGLDHGEA_1 | 3085429 | 3087048 | dhbE | 0.0 | Bacillibactin | Nutritional/Metabolic factor | 97.10 | 100.00 | NP_391078 |
BLASTN v2.16.0 (Database: VFDB, Dec. 2024 release)
VirulenceFinder
| Query ID | Begin | End | Database | Virulence factor | Protein function | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
VirulenceFinder v2.0. 4 (Database: virulencefinder_db, Feb . 2024 release)
Pathogenic genes
PHI-base
| Query ID | qstart | qend | Gene name | e-value | Function | Identity | Coverage | Gene ID |
|---|---|---|---|---|---|---|---|---|
| OGLDHGEA_1 | 131817 | 132953 | tufA | 0.0 | elongation factor Tu | 85.75 | 95.69 | AHM69299 |
| OGLDHGEA_1 | 17935 | 18804 | pdxS | 3.05e-149 | encodes the putative pyridoxal 5'-phosphate synthase subunit PdxS | 83.79 | 98.31 | ACE61268 |
| OGLDHGEA_1 | 1786289 | 1787065 | CodY | 3.34e-124 | nutrient-responsive regulator | 81.08 | 100.00 | ACJ80679 |
| OGLDHGEA_1 | 3431324 | 3431893 | ClpP | 2.47e-98 | part of proteolytic complex | 81.05 | 97.44 | BAB94595 |
BLASTX v2.16.0 (Database: PHI base v4.16, May. 2024 release)
Plasmid
PlasmidFinder
| Query ID | Begin | End | Plasmid | Query / Template | Identity | Accession no. |
|---|---|---|---|---|---|---|
| No hit found | ||||||
PlasmidFinder v 2.1.6 (Database: plasmidfinder_db v 2.2.0 , Nov. 2024 release)
PlasmidHunter
| Query ID | Prediction | Chromosome | Plasmid |
|---|---|---|---|
| OGLDHGEA_1 | 0.0 | 1.0 | 0.0 |
| OGLDHGEA_2 | 1.0 | 0.0 | 1.0 |
PlasmidHunter v 1.4.5 (Database: May. 2024 release)
Prophage
Phigaro
| Query ID | Begin | End | Transposable | Taxonomy | pVOGs |
|---|---|---|---|---|---|
| OGLDHGEA_1 | 1283865 | 1299322 | False | Siphoviridae | VOG0275, VOG4566, VOG5022, VOG0586, VOG9091, VOG1227, VOG6168, VOG0189, VOG0044, VOG0025, VOG4551, VOG2215, VOG1563, VOG4134, VOG7255, VOG10937 |
| OGLDHGEA_1 | 1325050 | 1350484 | False | Siphoviridae | VOG5023, VOG5012, VOG4555, VOG3676, VOG5504, VOG4564, VOG5589, VOG0799, VOG0725, VOG3636, VOG0801, VOG4619, VOG4626, VOG4612, VOG6243, VOG4705, VOG5221, VOG4574, VOG0602, VOG6116, VOG10051, VOG5216, VOG0275, VOG4602, VOG8483, VOG9667 |
| OGLDHGEA_1 | 1410071 | 1436754 | False | Myoviridae | VOG9667, VOG3490, VOG0189, VOG4861, VOG5447, VOG0796, VOG10227, VOG4773, VOG4685, VOG0749, VOG3890, VOG3891, VOG3892, VOG6163, VOG4865, VOG4885, VOG3894, VOG4550, VOG4691, VOG4862, VOG7718, VOG4705 |
| OGLDHGEA_1 | 3105728 | 3116460 | False | Siphoviridae | VOG0602, VOG4574, VOG5221, VOG4705, VOG6243, VOG4612, VOG4626, VOG4619, VOG0801 |
| OGLDHGEA_1 | 3120329 | 3126564 | False | Siphoviridae | VOG9317, VOG0692, VOG2613, VOG3699, VOG5023, VOG0275 |
| OGLDHGEA_1 | 3303919 | 3342447 | True | Siphoviridae | VOG0641, VOG4705, VOG6243, VOG4612, VOG4626, VOG4772, VOG0801, VOG5910, VOG0541, VOG4586, VOG0704, VOG9583, VOG0204, VOG10223, VOG4553, VOG4568, VOG4556, VOG3607, VOG1886, VOG4581, VOG0713, VOG4841, VOG0275, VOG0198, VOG0044, VOG0102, VOG0397, VOG5836, VOG0245, VOG1336, VOG6587, VOG0189, VOG4566, VOG7581, VOG9667, VOG9667, VOG1563, VOG0275, VOG0275 |
Phigaro v2.4.0 (Database: Jan. 2024 release)