Probiotic potential risk score
| ARGs | VFs | PGs | PPRS |
|---|---|---|---|
| 0 | 25 | 33 | 41.40 |
PPRS is classified as low-risk (≤4), medium-risk (4-6), and high-risk (≥6).
Antibiotic resistance genes
Comprehensive Antibiotic Resistance Database (CARD)
| Query ID | Begin | End | ARO name | ARO accession | CARD name | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
RGI v6.0.3 (Database: CARD Variants v4.0.2, Nov. 2023 release)
ResFinder
| Query ID | Begin | End | Resistance gene | Phenotype | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|
| No hit found | |||||||
ResFinder v4.6.0 (Database: resfinder_db, Aug. 2024 release)
AMRFinderPlus
| Query ID | Begin | End | Gene symbol | Sequence name | Method | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
AMRFinderPlus v4.0.3 (Database: Oct. 2024 release)
Virulence factors
Virulence Factor Database (VFDB)
| Query ID | qstart | qend | Gene name | e-value | VF name | VF category | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|---|
| BLPJNFBG_47 | 19475 | 20344 | rfbA | 0.0 | Capsule | Immune modulation | 100.00 | 100.00 | WP_011681286 |
| BLPJNFBG_47 | 20344 | 20937 | STER_RS06030 | 0.0 | Capsule | Immune modulation | 100.00 | 100.00 | WP_011226149 |
| BLPJNFBG_22 | 85509 | 86318 | STU_RS16245 | 0.0 | Capsule | Immune modulation | 99.88 | 100.00 | WP_002948020 |
| BLPJNFBG_47 | 20344 | 20937 | STR_RS05880 | 0.0 | Capsule | Immune modulation | 99.83 | 100.00 | WP_011226149 |
| BLPJNFBG_22 | 84569 | 85525 | STU_RS16250 | 0.0 | Capsule | Immune modulation | 99.79 | 100.00 | WP_011226328 |
| BLPJNFBG_22 | 83424 | 84572 | STU_RS16255 | 0.0 | Capsule | Immune modulation | 99.74 | 100.00 | WP_041828290 |
| BLPJNFBG_47 | 20344 | 20937 | STU_RS15260 | 0.0 | Capsule | Immune modulation | 99.66 | 100.00 | WP_011226149 |
| BLPJNFBG_22 | 79077 | 79928 | rfbD | 0.0 | Capsule | Immune modulation | 99.65 | 100.00 | WP_014621820 |
| BLPJNFBG_49 | 13060 | 14718 | fbp54 | 0.0 | FBPs | Adherence | 99.58 | 100.00 | WP_011227179 |
| BLPJNFBG_22 | 86318 | 87523 | STU_RS16240 | 0.0 | Capsule | Immune modulation | 99.58 | 100.00 | WP_011226326 |
| BLPJNFBG_22 | 82305 | 83315 | STU_RS16260 | 0.0 | Capsule | Immune modulation | 99.50 | 100.00 | WP_011226330 |
| BLPJNFBG_22 | 88595 | 90379 | STU_RS16230 | 0.0 | Capsule | Immune modulation | 99.44 | 100.00 | WP_011226325 |
| BLPJNFBG_22 | 87543 | 88598 | STU_RS16235 | 0.0 | Capsule | Immune modulation | 99.43 | 100.00 | WP_002948022 |
| BLPJNFBG_51 | 25849 | 26610 | srtA | 0.0 | Sortase A | Exoenzyme | 99.21 | 100.00 | - |
| BLPJNFBG_24 | 58009 | 58977 | cbpD | 0.0 | Autolysin | Exoenzyme | 98.76 | 100.00 | WP_082302295 |
| BLPJNFBG_74 | 2731 | 4146 | STER_RS05250 | 0.0 | Capsule | Immune modulation | 98.52 | 100.00 | WP_011681165 |
| BLPJNFBG_65 | 8268 | 8999 | STU_RS14645 | 0.0 | Capsule | Immune modulation | 98.36 | 100.00 | WP_011226048 |
| BLPJNFBG_29 | 52049 | 52837 | cshA | 0.0 | Cell surface hydrophobicity proteins | Adherence | 98.36 | 99.75 | - |
| BLPJNFBG_65 | 8268 | 8999 | STER_RS05315 | 0.0 | Capsule | Immune modulation | 98.09 | 100.00 | WP_011681176 |
| BLPJNFBG_65 | 8268 | 8999 | STR_RS05260 | 0.0 | Capsule | Immune modulation | 97.68 | 100.00 | WP_011227248 |
| BLPJNFBG_65 | 9000 | 10460 | STER_RS05320 | 0.0 | Capsule | Immune modulation | 97.54 | 100.00 | WP_011681177 |
| BLPJNFBG_22 | 81031 | 82302 | STU_RS16265 | 0.0 | Capsule | Immune modulation | 97.48 | 99.76 | WP_011226331 |
| BLPJNFBG_65 | 6817 | 7557 | STU_RS14635 | 0.0 | Capsule | Immune modulation | 97.30 | 100.00 | WP_011226046 |
| BLPJNFBG_65 | 6817 | 7557 | STER_RS05305 | 0.0 | Capsule | Immune modulation | 96.90 | 100.00 | WP_011681174 |
| BLPJNFBG_65 | 6822 | 7557 | STR_RS05250 | 0.0 | Capsule | Immune modulation | 96.33 | 98.13 | WP_011227246 |
| BLPJNFBG_65 | 9000 | 10460 | STU_RS14650 | 0.0 | Capsule | Immune modulation | 96.23 | 100.21 | WP_011226049 |
| BLPJNFBG_65 | 5393 | 6760 | STU_RS14630 | 0.0 | Capsule | Immune modulation | 95.47 | 100.00 | WP_011226045 |
| BLPJNFBG_65 | 9000 | 10460 | STR_RS05265 | 0.0 | Capsule | Immune modulation | 95.41 | 100.21 | WP_041827043 |
| BLPJNFBG_65 | 7567 | 8259 | STR_RS05255 | 0.0 | Capsule | Immune modulation | 95.40 | 99.86 | WP_011227247 |
| BLPJNFBG_65 | 7567 | 8259 | STU_RS14640 | 0.0 | Capsule | Immune modulation | 95.40 | 99.86 | WP_011226047 |
| BLPJNFBG_65 | 5395 | 6760 | STER_RS05300 | 0.0 | Capsule | Immune modulation | 94.22 | 99.85 | WP_011681173 |
| BLPJNFBG_65 | 7567 | 8259 | STER_RS05310 | 0.0 | Capsule | Immune modulation | 89.47 | 100.00 | WP_011681175 |
| BLPJNFBG_39 | 35701 | 37004 | eno | 0.0 | Streptococcal enolase | Exoenzyme | 88.09 | 99.54 | WP_000022832 |
| BLPJNFBG_58 | 90 | 1100 | plr/gapA | 0.0 | Streptococcal plasmin receptor/GAPDH | Adherence | 86.44 | 99.41 | WP_002986042 |
| BLPJNFBG_86 | 2714 | 3997 | tig/ropA | 0.0 | Trigger factor | Stress survival | 80.73 | 99.77 | WP_000107753 |
| BLPJNFBG_47 | 21366 | 22412 | rfbB | 0.0 | Capsule | Immune modulation | 80.61 | 100.00 | WP_009659423 |
BLASTN v2.16.0 (Database: VFDB, Dec. 2024 release)
VirulenceFinder
| Query ID | Begin | End | Database | Virulence factor | Protein function | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
VirulenceFinder v2.0. 4 (Database: virulencefinder_db, Feb . 2024 release)
Pathogenic genes
PHI-base
| Query ID | qstart | qend | Gene name | e-value | Function | Identity | Coverage | Gene ID |
|---|---|---|---|---|---|---|---|---|
| BLPJNFBG_51 | 23162 | 22179 | ldh(Sp_1220) | 0.0 | L-lactate dehydrogenase | 94.82 | 100.00 | AAK75326 |
| BLPJNFBG_66 | 13752 | 12679 | MntE | 0.0 | manganese homeostasis | 94.41 | 99.72 | ABF32167 |
| BLPJNFBG_11 | 15566 | 13263 | pfl2(Sp_0459) | 0.0 | formate acetyltransferase | 92.97 | 99.22 | AAK74619 |
| BLPJNFBG_40 | 50105 | 49137 | spr0084 | 0.0 | pathogenitcity related | 92.57 | 98.48 | AAK98888 |
| BLPJNFBG_57 | 11328 | 9082 | metE | 0.0 | methionine biosynthesis enzymes | 91.99 | 100.00 | AAK74738 |
| BLPJNFBG_36 | 46604 | 48085 | SPD_0310 | 0.0 | UPF0371 protein SPD_0310 | 91.50 | 100.00 | ABJ54480 |
| BLPJNFBG_73 | 20232 | 21224 | recA | 0.0 | DNA recombination and repair | 91.24 | 85.31 | AAL00560 |
| BLPJNFBG_78 | 3366 | 4337 | prsA2 | 0.0 | ribose-phosphate pyrophosphokinase | 90.12 | 100.00 | ABF36968 |
| BLPJNFBG_22 | 29119 | 30270 | potA | 0.0 | ABC transporter ATP-binding protein-spermidine/putrescine transport | 89.32 | 99.74 | AAL00050 |
| BLPJNFBG_22 | 64087 | 66075 | uvrB | 0.0 | excinuclease ABC, B subunit | 88.84 | 100.00 | AE014259_2 |
| BLPJNFBG_51 | 39383 | 41113 | ptsI | 0.0 | phosphoenolpyruvate-protein phosphotransferase | 87.87 | 100.00 | AAK34199 |
| BLPJNFBG_33 | 27030 | 28508 | IMPDH | 0.0 | inosine-5'-monophosphate dehydrogenase | 87.42 | 100.00 | ADE32434 |
| BLPJNFBG_33 | 42219 | 44111 | gidA | 0.0 | tRNA uridine 5-carboxymethylaminomethyl modification enzyme | 86.05 | 98.90 | ABP91129 |
| BLPJNFBG_39 | 35701 | 37002 | Eno | 0.0 | enolase | 85.98 | 99.77 | ABP90468 |
| BLPJNFBG_57 | 6157 | 7866 | PGM | 0.0 | phosphoglucomutase | 83.89 | 99.65 | ACH87041 |
| BLPJNFBG_25 | 2070 | 1060 | pdh | 0.0 | pyruvate dehydrogenase | 82.79 | 99.70 | ABP91006 |
| BLPJNFBG_49 | 41207 | 39846 | mnmE | 0.0 | central tRNA-modifying GTPase | 81.80 | 99.56 | ABP90420 |
| BLPJNFBG_20 | 15684 | 13792 | PepO | 0.0 | endopeptidase | 80.19 | 100.00 | ABF32980 |
| BLPJNFBG_39 | 21274 | 22164 | bglB | 1.20e-179 | putative phospho--glucosidase | 88.55 | 99.66 | AAK33487 |
| BLPJNFBG_96 | 11824 | 10889 | SP_0676 | 2.07e-169 | transcription facot | 81.73 | 96.89 | AAK74821 |
| BLPJNFBG_57 | 8890 | 8033 | metF | 4.27e-166 | methionine biosynthesis enzymes | 86.01 | 99.31 | AAK74739 |
| BLPJNFBG_29 | 24433 | 23729 | covR | 1.27e-132 | responder protein | 85.53 | 100.00 | AAK71319 |
| BLPJNFBG_36 | 27636 | 26965 | rr01 | 2.63e-124 | response regulator | 83.04 | 99.56 | CAB54566 |
| BLPJNFBG_29 | 24433 | 23729 | walR | 5.35e-123 | DNA-binding response regulator | 82.13 | 100.00 | ANC99504 |
| BLPJNFBG_57 | 2203 | 1535 | CiaR | 8.71e-120 | two-component response regulator | 84.75 | 99.55 | AAK74935 |
| BLPJNFBG_61 | 7708 | 7022 | CovR | 1.29e-119 | serves to repress GAS virulence factor-encoding genes | 80.79 | 100.00 | ACE75886 |
| BLPJNFBG_57 | 2203 | 1532 | ciaR | 9.44e-118 | two component system response regulator | 82.59 | 99.12 | AIK75708 |
| BLPJNFBG_73 | 21521 | 21916 | SpxA2 | 4.39e-76 | transcriptional regulator | 90.91 | 100.00 | ERL21461 |
| BLPJNFBG_49 | 52566 | 52967 | SpxA1 | 1.45e-67 | transcriptional regulator | 80.60 | 100.00 | ERL19273 |
| BLPJNFBG_75 | 10226 | 9939 | spr0479 | 1.77e-49 | essential gene | 86.46 | 98.97 | AAK99283 |
| BLPJNFBG_24 | 99861 | 100115 | spr1327 | 1.09e-44 | essential gene | 94.12 | 100.00 | AAL00131 |
| BLPJNFBG_33 | 75863 | 75600 | spr0175 | 5.04e-42 | pathogenitcity related | 84.09 | 100.00 | AAK98979 |
| BLPJNFBG_33 | 75036 | 74770 | spr0177 | 8.90e-34 | essential gene | 84.27 | 88.12 | AAK98981 |
| BLPJNFBG_86 | 4155 | 4655 | RopE (M5005_Spy_1611) | 1.71e-76 | probable DNA-directed RNA polymerase subunit delta | 81.44 | 87.43 | AAK34603 |
| BLPJNFBG_11 | 15566 | 13269 | PFL (B9H01_RS01125) | 0.0 | formate C-acetyltransferase | 82.94 | 98.08 | MYN69560 |
| BLPJNFBG_20 | 1209 | 190 | ilvC (SPD_0406) | 0.0 | ketol-acid reductoisomerase (NADP(+)) | 96.47 | 100.00 | ABJ55451 |
BLASTX v2.16.0 (Database: PHI base v4.16, May. 2024 release)
Plasmid
PlasmidFinder
| Query ID | Begin | End | Plasmid | Query / Template | Identity | Accession no. |
|---|---|---|---|---|---|---|
| No hit found | ||||||
PlasmidFinder v 2.1.6 (Database: plasmidfinder_db v 2.2.0 , Nov. 2024 release)
PlasmidHunter
| Query ID | Prediction | Chromosome | Plasmid |
|---|---|---|---|
| BLPJNFBG_11 | 0.0 | 1.0 | 0.0 |
| BLPJNFBG_19 | 0.0 | 1.0 | 0.0 |
| BLPJNFBG_20 | 0.0 | 1.0 | 0.0 |
| BLPJNFBG_21 | 0.0 | 1.0 | 0.0 |
| BLPJNFBG_22 | 0.0 | 1.0 | 0.0 |
| BLPJNFBG_24 | 0.0 | 1.0 | 0.0 |
| BLPJNFBG_25 | 0.0 | 1.0 | 0.0 |
| BLPJNFBG_26 | 0.0 | 1.0 | 0.0 |
| BLPJNFBG_27 | 0.0 | 1.0 | 0.0 |
| BLPJNFBG_28 | 0.0 | 1.0 | 0.0 |
| BLPJNFBG_29 | 0.0 | 1.0 | 0.0 |
| BLPJNFBG_32 | 0.0 | 1.0 | 0.0 |
| BLPJNFBG_33 | 0.0 | 1.0 | 0.0 |
| BLPJNFBG_34 | 0.0 | 1.0 | 0.0 |
| BLPJNFBG_35 | 0.0 | 1.0 | 0.0 |
| BLPJNFBG_36 | 0.0 | 1.0 | 0.0 |
| BLPJNFBG_38 | 0.0 | 1.0 | 0.0 |
| BLPJNFBG_39 | 0.0 | 1.0 | 0.0 |
| BLPJNFBG_40 | 0.0 | 1.0 | 0.0 |
| BLPJNFBG_41 | 0.0 | 1.0 | 0.0 |
| BLPJNFBG_42 | 0.0 | 1.0 | 0.0 |
| BLPJNFBG_43 | 0.0 | 1.0 | 0.0 |
| BLPJNFBG_44 | 0.0 | 1.0 | 0.0 |
| BLPJNFBG_46 | 0.0 | 1.0 | 0.0 |
| BLPJNFBG_47 | 0.0 | 1.0 | 0.0 |
| BLPJNFBG_48 | 0.0 | 1.0 | 0.0 |
| BLPJNFBG_49 | 0.0 | 1.0 | 0.0 |
| BLPJNFBG_50 | 0.0 | 1.0 | 0.0 |
| BLPJNFBG_51 | 0.0 | 1.0 | 0.0 |
| BLPJNFBG_53 | 0.0 | 1.0 | 0.0 |
| BLPJNFBG_54 | 0.0 | 1.0 | 0.0 |
| BLPJNFBG_55 | 1.0 | 0.0 | 1.0 |
| BLPJNFBG_57 | 0.0 | 1.0 | 0.0 |
| BLPJNFBG_58 | 0.0 | 1.0 | 0.0 |
| BLPJNFBG_59 | 1.0 | 0.0 | 1.0 |
| BLPJNFBG_61 | 0.0 | 1.0 | 0.0 |
| BLPJNFBG_63 | 0.0 | 1.0 | 0.0 |
| BLPJNFBG_64 | 0.0 | 1.0 | 0.0 |
| BLPJNFBG_65 | 0.0 | 1.0 | 0.0 |
| BLPJNFBG_66 | 0.0 | 1.0 | 0.0 |
| BLPJNFBG_68 | 0.0 | 1.0 | 0.0 |
| BLPJNFBG_69 | 0.0 | 1.0 | 0.0 |
| BLPJNFBG_70 | 0.0 | 1.0 | 0.0 |
| BLPJNFBG_71 | 0.0 | 1.0 | 0.0 |
| BLPJNFBG_73 | 0.0 | 1.0 | 0.0 |
| BLPJNFBG_74 | 1.0 | 0.0 | 1.0 |
| BLPJNFBG_75 | 0.0 | 1.0 | 0.0 |
| BLPJNFBG_76 | 0.0 | 1.0 | 0.0 |
| BLPJNFBG_77 | 0.0 | 1.0 | 0.0 |
| BLPJNFBG_78 | 0.0 | 1.0 | 0.0 |
| BLPJNFBG_79 | 0.0 | 1.0 | 0.0 |
| BLPJNFBG_82 | 0.0 | 1.0 | 0.0 |
| BLPJNFBG_84 | 0.0 | 1.0 | 0.0 |
| BLPJNFBG_85 | 0.0 | 1.0 | 0.0 |
| BLPJNFBG_86 | 0.0 | 1.0 | 0.0 |
| BLPJNFBG_89 | 1.0 | 0.0 | 1.0 |
| BLPJNFBG_94 | 0.0 | 1.0 | 0.0 |
| BLPJNFBG_95 | 1.0 | 0.0 | 1.0 |
| BLPJNFBG_96 | 0.0 | 1.0 | 0.0 |
| BLPJNFBG_98 | 0.0 | 1.0 | 0.0 |
| BLPJNFBG_99 | 0.0 | 1.0 | 0.0 |
| BLPJNFBG_104 | 0.0 | 1.0 | 0.0 |
PlasmidHunter v 1.4.5 (Database: May. 2024 release)
Prophage
Phigaro
| Query ID | Begin | End | Transposable | Taxonomy | pVOGs |
|---|---|---|---|---|---|
| No hit found | |||||
Phigaro v2.4.0 (Database: Jan. 2024 release)