Probiotic potential risk score
| ARGs | VFs | PGs | PPRS |
|---|---|---|---|
| 0 | 27 | 35 | 44.20 |
PPRS is classified as low-risk (≤4), medium-risk (4-6), and high-risk (≥6).
Antibiotic resistance genes
Comprehensive Antibiotic Resistance Database (CARD)
| Query ID | Begin | End | ARO name | ARO accession | CARD name | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
RGI v6.0.3 (Database: CARD Variants v4.0.2, Nov. 2023 release)
ResFinder
| Query ID | Begin | End | Resistance gene | Phenotype | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|
| No hit found | |||||||
ResFinder v4.6.0 (Database: resfinder_db, Aug. 2024 release)
AMRFinderPlus
| Query ID | Begin | End | Gene symbol | Sequence name | Method | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
AMRFinderPlus v4.0.3 (Database: Oct. 2024 release)
Virulence factors
Virulence Factor Database (VFDB)
| Query ID | qstart | qend | Gene name | e-value | VF name | VF category | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|---|
| PFEKKOIM_43 | 9591 | 10460 | rfbA | 0.0 | Capsule | Immune modulation | 100.00 | 100.00 | WP_011681286 |
| PFEKKOIM_43 | 8998 | 9591 | STER_RS06030 | 0.0 | Capsule | Immune modulation | 100.00 | 100.00 | WP_011226149 |
| PFEKKOIM_40 | 6423 | 7232 | STU_RS16245 | 0.0 | Capsule | Immune modulation | 99.88 | 100.00 | WP_002948020 |
| PFEKKOIM_43 | 8998 | 9591 | STR_RS05880 | 0.0 | Capsule | Immune modulation | 99.83 | 100.00 | WP_011226149 |
| PFEKKOIM_40 | 7216 | 8172 | STU_RS16250 | 0.0 | Capsule | Immune modulation | 99.79 | 100.00 | WP_011226328 |
| PFEKKOIM_40 | 8169 | 9317 | STU_RS16255 | 0.0 | Capsule | Immune modulation | 99.74 | 100.00 | WP_041828290 |
| PFEKKOIM_43 | 8998 | 9591 | STU_RS15260 | 0.0 | Capsule | Immune modulation | 99.66 | 100.00 | WP_011226149 |
| PFEKKOIM_40 | 12813 | 13664 | rfbD | 0.0 | Capsule | Immune modulation | 99.65 | 100.00 | WP_014621820 |
| PFEKKOIM_74 | 13157 | 14815 | fbp54 | 0.0 | FBPs | Adherence | 99.58 | 100.00 | WP_011227179 |
| PFEKKOIM_40 | 5218 | 6423 | STU_RS16240 | 0.0 | Capsule | Immune modulation | 99.58 | 100.00 | WP_011226326 |
| PFEKKOIM_65 | 15997 | 16596 | STR_RS05245 | 0.0 | Capsule | Immune modulation | 99.50 | 100.00 | WP_196767671 |
| PFEKKOIM_40 | 9426 | 10436 | STU_RS16260 | 0.0 | Capsule | Immune modulation | 99.50 | 100.00 | WP_011226330 |
| PFEKKOIM_40 | 2362 | 4146 | STU_RS16230 | 0.0 | Capsule | Immune modulation | 99.44 | 100.00 | WP_011226325 |
| PFEKKOIM_40 | 4143 | 5198 | STU_RS16235 | 0.0 | Capsule | Immune modulation | 99.43 | 100.00 | WP_002948022 |
| PFEKKOIM_78 | 595 | 2010 | STER_RS05250 | 0.0 | Capsule | Immune modulation | 99.15 | 100.00 | WP_011681165 |
| PFEKKOIM_65 | 15110 | 15845 | STER_RS05305 | 0.0 | Capsule | Immune modulation | 98.91 | 99.33 | WP_011681174 |
| PFEKKOIM_32 | 59040 | 60008 | cbpD | 0.0 | Autolysin | Exoenzyme | 98.86 | 100.00 | WP_082302295 |
| PFEKKOIM_38 | 25563 | 26324 | srtA | 0.0 | Sortase A | Exoenzyme | 98.82 | 100.00 | - |
| PFEKKOIM_65 | 13668 | 14399 | STER_RS05315 | 0.0 | Capsule | Immune modulation | 98.77 | 100.00 | WP_011681176 |
| PFEKKOIM_65 | 12213 | 13667 | STR_RS05265 | 0.0 | Capsule | Immune modulation | 98.76 | 100.00 | WP_041827043 |
| PFEKKOIM_65 | 16761 | 17720 | STR_RS05240 | 0.0 | Capsule | Immune modulation | 98.54 | 100.00 | WP_041827042 |
| PFEKKOIM_65 | 13668 | 14399 | STU_RS14645 | 0.0 | Capsule | Immune modulation | 98.50 | 100.00 | WP_011226048 |
| PFEKKOIM_58 | 52123 | 52916 | cshA | 0.0 | Cell surface hydrophobicity proteins | Adherence | 98.36 | 100.25 | - |
| PFEKKOIM_65 | 13668 | 14399 | STR_RS05260 | 0.0 | Capsule | Immune modulation | 98.36 | 100.00 | WP_011227248 |
| PFEKKOIM_65 | 15110 | 15859 | STR_RS05250 | 0.0 | Capsule | Immune modulation | 98.27 | 100.00 | WP_011227246 |
| PFEKKOIM_65 | 12213 | 13667 | STU_RS14650 | 0.0 | Capsule | Immune modulation | 98.21 | 100.00 | WP_011226049 |
| PFEKKOIM_65 | 15110 | 15845 | STU_RS14635 | 0.0 | Capsule | Immune modulation | 98.10 | 99.33 | WP_011226046 |
| PFEKKOIM_40 | 10439 | 11710 | STU_RS16265 | 0.0 | Capsule | Immune modulation | 97.48 | 99.76 | WP_011226331 |
| PFEKKOIM_65 | 12213 | 13667 | STER_RS05320 | 0.0 | Capsule | Immune modulation | 96.65 | 99.79 | WP_011681177 |
| PFEKKOIM_39 | 22033 | 26927 | SAG_RS09105 | 0.0 | Agglutinin receptor | Adherence | 92.87 | 99.98 | WP_000167699 |
| PFEKKOIM_39 | 21985 | 26927 | SSU98_0978 | 0.0 | Agglutinin receptor | Adherence | 92.82 | 99.78 | YP_001200536 |
| PFEKKOIM_39 | 21985 | 26927 | SSU05_0965 | 0.0 | Agglutinin receptor | Adherence | 92.80 | 99.78 | YP_001198331 |
| PFEKKOIM_65 | 14408 | 15100 | STER_RS05310 | 0.0 | Capsule | Immune modulation | 89.90 | 100.00 | WP_011681175 |
| PFEKKOIM_65 | 14408 | 15100 | STU_RS14640 | 0.0 | Capsule | Immune modulation | 89.75 | 100.00 | WP_011226047 |
| PFEKKOIM_65 | 14408 | 15100 | STR_RS05255 | 0.0 | Capsule | Immune modulation | 89.47 | 100.00 | WP_011227247 |
| PFEKKOIM_35 | 96835 | 98138 | eno | 0.0 | Streptococcal enolase | Exoenzyme | 88.10 | 99.46 | WP_000022832 |
| PFEKKOIM_28 | 14333 | 15343 | plr/gapA | 0.0 | Streptococcal plasmin receptor/GAPDH | Adherence | 86.54 | 99.41 | WP_002986042 |
| PFEKKOIM_47 | 4787 | 6070 | tig/ropA | 0.0 | Trigger factor | Stress survival | 80.73 | 99.77 | WP_000107753 |
| PFEKKOIM_43 | 7523 | 8569 | rfbB | 0.0 | Capsule | Immune modulation | 80.61 | 100.00 | WP_009659423 |
BLASTN v2.16.0 (Database: VFDB, Dec. 2024 release)
VirulenceFinder
| Query ID | Begin | End | Database | Virulence factor | Protein function | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
VirulenceFinder v2.0. 4 (Database: virulencefinder_db, Feb . 2024 release)
Pathogenic genes
PHI-base
| Query ID | qstart | qend | Gene name | e-value | Function | Identity | Coverage | Gene ID |
|---|---|---|---|---|---|---|---|---|
| PFEKKOIM_38 | 22876 | 21893 | ldh(Sp_1220) | 0.0 | L-lactate dehydrogenase | 94.82 | 100.00 | AAK75326 |
| PFEKKOIM_46 | 6711 | 7784 | MntE | 0.0 | manganese homeostasis | 94.41 | 99.72 | ABF32167 |
| PFEKKOIM_39 | 22012 | 26922 | B9H01_RS04765 | 0.0 | glucan-binding protein | 93.40 | 99.63 | AUS90958 |
| PFEKKOIM_35 | 13149 | 14117 | spr0084 | 0.0 | pathogenitcity related | 93.19 | 98.48 | AAK98888 |
| PFEKKOIM_27 | 15570 | 13267 | pfl2(Sp_0459) | 0.0 | formate acetyltransferase | 92.97 | 99.22 | AAK74619 |
| PFEKKOIM_36 | 13142 | 11661 | SPD_0310 | 0.0 | UPF0371 protein SPD_0310 | 92.31 | 100.00 | ABJ54480 |
| PFEKKOIM_68 | 11362 | 9116 | metE | 0.0 | methionine biosynthesis enzymes | 91.72 | 100.00 | AAK74738 |
| PFEKKOIM_64 | 12611 | 13609 | recA | 0.0 | DNA recombination and repair | 91.29 | 85.82 | AAL00560 |
| PFEKKOIM_80 | 3368 | 4339 | prsA2 | 0.0 | ribose-phosphate pyrophosphokinase | 90.12 | 100.00 | ABF36968 |
| PFEKKOIM_42 | 73116 | 74267 | potA | 0.0 | ABC transporter ATP-binding protein-spermidine/putrescine transport | 89.32 | 99.74 | AAL00050 |
| PFEKKOIM_40 | 28634 | 26646 | uvrB | 0.0 | excinuclease ABC, B subunit | 88.99 | 100.00 | AE014259_2 |
| PFEKKOIM_38 | 39075 | 40805 | ptsI | 0.0 | phosphoenolpyruvate-protein phosphotransferase | 88.04 | 100.00 | AAK34199 |
| PFEKKOIM_72 | 69895 | 68417 | IMPDH | 0.0 | inosine-5'-monophosphate dehydrogenase | 87.22 | 100.00 | ADE32434 |
| PFEKKOIM_35 | 96835 | 98136 | Eno | 0.0 | enolase | 86.21 | 99.77 | ABP90468 |
| PFEKKOIM_72 | 54706 | 52814 | gidA | 0.0 | tRNA uridine 5-carboxymethylaminomethyl modification enzyme | 86.05 | 98.90 | ABP91129 |
| PFEKKOIM_68 | 6191 | 7900 | PGM | 0.0 | phosphoglucomutase | 83.71 | 99.65 | ACH87041 |
| PFEKKOIM_76 | 2072 | 1062 | pdh | 0.0 | pyruvate dehydrogenase | 83.09 | 99.70 | ABP91006 |
| PFEKKOIM_37 | 30234 | 31595 | mnmE | 0.0 | central tRNA-modifying GTPase | 82.24 | 99.56 | ABP90420 |
| PFEKKOIM_45 | 4720 | 6612 | PepO | 0.0 | endopeptidase | 80.19 | 100.00 | ABF32980 |
| PFEKKOIM_35 | 82400 | 83290 | bglB | 1.06e-179 | putative phospho--glucosidase | 88.89 | 99.66 | AAK33487 |
| PFEKKOIM_26 | 3945 | 3007 | SP_0676 | 5.99e-169 | transcription facot | 81.15 | 97.20 | AAK74821 |
| PFEKKOIM_68 | 8924 | 8067 | metF | 1.40e-166 | methionine biosynthesis enzymes | 86.36 | 99.31 | AAK74739 |
| PFEKKOIM_58 | 24442 | 23738 | covR | 1.26e-132 | responder protein | 85.53 | 100.00 | AAK71319 |
| PFEKKOIM_44 | 22943 | 23614 | rr01 | 6.85e-126 | response regulator | 83.93 | 99.56 | CAB54566 |
| PFEKKOIM_58 | 24442 | 23738 | walR | 5.31e-123 | DNA-binding response regulator | 82.13 | 100.00 | ANC99504 |
| PFEKKOIM_52 | 7744 | 7058 | CovR | 1.31e-119 | serves to repress GAS virulence factor-encoding genes | 80.79 | 100.00 | ACE75886 |
| PFEKKOIM_68 | 2238 | 1570 | CiaR | 1.86e-119 | two-component response regulator | 84.31 | 99.55 | AAK74935 |
| PFEKKOIM_68 | 2238 | 1567 | ciaR | 1.83e-117 | two component system response regulator | 82.14 | 99.12 | AIK75708 |
| PFEKKOIM_64 | 13885 | 14259 | SpxA2 | 8.91e-72 | transcriptional regulator | 91.20 | 94.70 | ERL21461 |
| PFEKKOIM_37 | 18875 | 18474 | SpxA1 | 1.10e-67 | transcriptional regulator | 80.60 | 100.00 | ERL19273 |
| PFEKKOIM_66 | 13132 | 13419 | spr0479 | 1.31e-48 | essential gene | 85.42 | 98.97 | AAK99283 |
| PFEKKOIM_32 | 18150 | 17896 | spr1327 | 1.11e-45 | essential gene | 95.29 | 100.00 | AAL00131 |
| PFEKKOIM_72 | 10154 | 10417 | spr0175 | 4.62e-42 | pathogenitcity related | 84.09 | 100.00 | AAK98979 |
| PFEKKOIM_72 | 10981 | 11247 | spr0177 | 8.16e-34 | essential gene | 84.27 | 88.12 | AAK98981 |
| PFEKKOIM_47 | 6228 | 6728 | RopE (M5005_Spy_1611) | 1.82e-76 | probable DNA-directed RNA polymerase subunit delta | 81.44 | 87.43 | AAK34603 |
| PFEKKOIM_27 | 15570 | 13273 | PFL (B9H01_RS01125) | 0.0 | formate C-acetyltransferase | 82.94 | 98.08 | MYN69560 |
| PFEKKOIM_39 | 56635 | 57831 | AUS90997 (B9H01_RS07385) | 0.0 | site-specific integrase | 97.74 | 100.00 | AUS90997 |
| PFEKKOIM_45 | 19192 | 20211 | ilvC (SPD_0406) | 0.0 | ketol-acid reductoisomerase (NADP(+)) | 96.47 | 100.00 | ABJ55451 |
BLASTX v2.16.0 (Database: PHI base v4.16, May. 2024 release)
Plasmid
PlasmidFinder
| Query ID | Begin | End | Plasmid | Query / Template | Identity | Accession no. |
|---|---|---|---|---|---|---|
| No hit found | ||||||
PlasmidFinder v 2.1.6 (Database: plasmidfinder_db v 2.2.0 , Nov. 2024 release)
PlasmidHunter
| Query ID | Prediction | Chromosome | Plasmid |
|---|---|---|---|
| PFEKKOIM_20 | 0.0 | 1.0 | 0.0 |
| PFEKKOIM_26 | 0.0 | 1.0 | 0.0 |
| PFEKKOIM_27 | 0.0 | 1.0 | 0.0 |
| PFEKKOIM_28 | 0.0 | 1.0 | 0.0 |
| PFEKKOIM_29 | 0.0 | 1.0 | 0.0 |
| PFEKKOIM_31 | 0.0 | 1.0 | 0.0 |
| PFEKKOIM_32 | 0.0 | 1.0 | 0.0 |
| PFEKKOIM_34 | 0.0 | 1.0 | 0.0 |
| PFEKKOIM_35 | 0.0 | 1.0 | 0.0 |
| PFEKKOIM_36 | 0.0 | 1.0 | 0.0 |
| PFEKKOIM_37 | 0.0 | 1.0 | 0.0 |
| PFEKKOIM_38 | 0.0 | 1.0 | 0.0 |
| PFEKKOIM_39 | 0.0 | 1.0 | 0.0 |
| PFEKKOIM_40 | 0.0 | 1.0 | 0.0 |
| PFEKKOIM_41 | 0.0 | 1.0 | 0.0 |
| PFEKKOIM_42 | 0.0 | 1.0 | 0.0 |
| PFEKKOIM_43 | 0.0 | 1.0 | 0.0 |
| PFEKKOIM_44 | 0.0 | 1.0 | 0.0 |
| PFEKKOIM_45 | 0.0 | 1.0 | 0.0 |
| PFEKKOIM_46 | 0.0 | 1.0 | 0.0 |
| PFEKKOIM_47 | 0.0 | 1.0 | 0.0 |
| PFEKKOIM_48 | 0.0 | 1.0 | 0.0 |
| PFEKKOIM_50 | 0.0 | 1.0 | 0.0 |
| PFEKKOIM_51 | 0.0 | 1.0 | 0.0 |
| PFEKKOIM_52 | 0.0 | 1.0 | 0.0 |
| PFEKKOIM_53 | 0.0 | 1.0 | 0.0 |
| PFEKKOIM_54 | 0.0 | 1.0 | 0.0 |
| PFEKKOIM_55 | 0.0 | 1.0 | 0.0 |
| PFEKKOIM_56 | 1.0 | 0.0 | 1.0 |
| PFEKKOIM_58 | 0.0 | 1.0 | 0.0 |
| PFEKKOIM_59 | 0.0 | 1.0 | 0.0 |
| PFEKKOIM_60 | 0.0 | 1.0 | 0.0 |
| PFEKKOIM_61 | 0.0 | 1.0 | 0.0 |
| PFEKKOIM_62 | 0.0 | 1.0 | 0.0 |
| PFEKKOIM_63 | 0.0 | 1.0 | 0.0 |
| PFEKKOIM_64 | 0.0 | 1.0 | 0.0 |
| PFEKKOIM_65 | 0.0 | 1.0 | 0.0 |
| PFEKKOIM_66 | 0.0 | 1.0 | 0.0 |
| PFEKKOIM_67 | 1.0 | 0.0 | 1.0 |
| PFEKKOIM_68 | 0.0 | 1.0 | 0.0 |
| PFEKKOIM_69 | 0.0 | 1.0 | 0.0 |
| PFEKKOIM_70 | 0.0 | 1.0 | 0.0 |
| PFEKKOIM_71 | 0.0 | 1.0 | 0.0 |
| PFEKKOIM_72 | 0.0 | 1.0 | 0.0 |
| PFEKKOIM_74 | 0.0 | 1.0 | 0.0 |
| PFEKKOIM_75 | 0.0 | 1.0 | 0.0 |
| PFEKKOIM_76 | 0.0 | 1.0 | 0.0 |
| PFEKKOIM_78 | 1.0 | 0.0 | 1.0 |
| PFEKKOIM_79 | 0.0 | 1.0 | 0.0 |
| PFEKKOIM_80 | 0.0 | 1.0 | 0.0 |
| PFEKKOIM_81 | 0.0 | 1.0 | 0.0 |
| PFEKKOIM_82 | 0.0 | 1.0 | 0.0 |
| PFEKKOIM_84 | 0.0 | 1.0 | 0.0 |
| PFEKKOIM_85 | 1.0 | 0.0 | 1.0 |
| PFEKKOIM_86 | 0.0 | 1.0 | 0.0 |
| PFEKKOIM_88 | 0.0 | 1.0 | 0.0 |
| PFEKKOIM_89 | 1.0 | 0.0 | 1.0 |
| PFEKKOIM_91 | 0.0 | 1.0 | 0.0 |
| PFEKKOIM_92 | 0.0 | 1.0 | 0.0 |
| PFEKKOIM_93 | 1.0 | 0.0 | 1.0 |
| PFEKKOIM_94 | 1.0 | 0.0 | 1.0 |
| PFEKKOIM_95 | 1.0 | 0.0 | 1.0 |
| PFEKKOIM_96 | 0.0 | 1.0 | 0.0 |
| PFEKKOIM_97 | 1.0 | 0.0 | 1.0 |
| PFEKKOIM_98 | 0.0 | 1.0 | 0.0 |
| PFEKKOIM_102 | 0.0 | 1.0 | 0.0 |
| PFEKKOIM_109 | 0.0 | 1.0 | 0.0 |
| PFEKKOIM_112 | 1.0 | 0.0 | 1.0 |
PlasmidHunter v 1.4.5 (Database: May. 2024 release)
Prophage
Phigaro
| Query ID | Begin | End | Transposable | Taxonomy | pVOGs |
|---|---|---|---|---|---|
| No hit found | |||||
Phigaro v2.4.0 (Database: Jan. 2024 release)