Probiotic potential risk score
| ARGs | VFs | PGs | PPRS |
|---|---|---|---|
| 0 | 27 | 35 | 44.20 |
PPRS is classified as low-risk (≤4), medium-risk (4-6), and high-risk (≥6).
Antibiotic resistance genes
Comprehensive Antibiotic Resistance Database (CARD)
| Query ID | Begin | End | ARO name | ARO accession | CARD name | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
RGI v6.0.3 (Database: CARD Variants v4.0.2, Nov. 2023 release)
ResFinder
| Query ID | Begin | End | Resistance gene | Phenotype | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|
| No hit found | |||||||
ResFinder v4.6.0 (Database: resfinder_db, Aug. 2024 release)
AMRFinderPlus
| Query ID | Begin | End | Gene symbol | Sequence name | Method | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
AMRFinderPlus v4.0.3 (Database: Oct. 2024 release)
Virulence factors
Virulence Factor Database (VFDB)
| Query ID | qstart | qend | Gene name | e-value | VF name | VF category | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|---|
| EOGNBIFH_65 | 9591 | 10460 | rfbA | 0.0 | Capsule | Immune modulation | 100.00 | 100.00 | WP_011681286 |
| EOGNBIFH_65 | 8998 | 9591 | STER_RS06030 | 0.0 | Capsule | Immune modulation | 100.00 | 100.00 | WP_011226149 |
| EOGNBIFH_79 | 6421 | 7230 | STU_RS16245 | 0.0 | Capsule | Immune modulation | 99.88 | 100.00 | WP_002948020 |
| EOGNBIFH_65 | 8998 | 9591 | STR_RS05880 | 0.0 | Capsule | Immune modulation | 99.83 | 100.00 | WP_011226149 |
| EOGNBIFH_79 | 7214 | 8170 | STU_RS16250 | 0.0 | Capsule | Immune modulation | 99.79 | 100.00 | WP_011226328 |
| EOGNBIFH_79 | 8167 | 9315 | STU_RS16255 | 0.0 | Capsule | Immune modulation | 99.74 | 100.00 | WP_041828290 |
| EOGNBIFH_65 | 8998 | 9591 | STU_RS15260 | 0.0 | Capsule | Immune modulation | 99.66 | 100.00 | WP_011226149 |
| EOGNBIFH_79 | 12811 | 13662 | rfbD | 0.0 | Capsule | Immune modulation | 99.65 | 100.00 | WP_014621820 |
| EOGNBIFH_4 | 13057 | 14715 | fbp54 | 0.0 | FBPs | Adherence | 99.58 | 100.00 | WP_011227179 |
| EOGNBIFH_79 | 5216 | 6421 | STU_RS16240 | 0.0 | Capsule | Immune modulation | 99.58 | 100.00 | WP_011226326 |
| EOGNBIFH_71 | 13438 | 14037 | STR_RS05245 | 0.0 | Capsule | Immune modulation | 99.50 | 100.00 | WP_196767671 |
| EOGNBIFH_79 | 9424 | 10434 | STU_RS16260 | 0.0 | Capsule | Immune modulation | 99.50 | 100.00 | WP_011226330 |
| EOGNBIFH_79 | 2360 | 4144 | STU_RS16230 | 0.0 | Capsule | Immune modulation | 99.44 | 100.00 | WP_011226325 |
| EOGNBIFH_79 | 4141 | 5196 | STU_RS16235 | 0.0 | Capsule | Immune modulation | 99.43 | 100.00 | WP_002948022 |
| EOGNBIFH_35 | 593 | 2008 | STER_RS05250 | 0.0 | Capsule | Immune modulation | 99.15 | 100.00 | WP_011681165 |
| EOGNBIFH_71 | 14189 | 14924 | STER_RS05305 | 0.0 | Capsule | Immune modulation | 98.91 | 99.33 | WP_011681174 |
| EOGNBIFH_103 | 59038 | 60006 | cbpD | 0.0 | Autolysin | Exoenzyme | 98.86 | 100.00 | WP_082302295 |
| EOGNBIFH_129 | 14619 | 15380 | srtA | 0.0 | Sortase A | Exoenzyme | 98.82 | 100.00 | - |
| EOGNBIFH_71 | 15635 | 16366 | STER_RS05315 | 0.0 | Capsule | Immune modulation | 98.77 | 100.00 | WP_011681176 |
| EOGNBIFH_71 | 16367 | 17821 | STR_RS05265 | 0.0 | Capsule | Immune modulation | 98.76 | 100.00 | WP_041827043 |
| EOGNBIFH_71 | 12314 | 13273 | STR_RS05240 | 0.0 | Capsule | Immune modulation | 98.54 | 100.00 | WP_041827042 |
| EOGNBIFH_71 | 15635 | 16366 | STU_RS14645 | 0.0 | Capsule | Immune modulation | 98.50 | 100.00 | WP_011226048 |
| EOGNBIFH_133 | 52121 | 52914 | cshA | 0.0 | Cell surface hydrophobicity proteins | Adherence | 98.36 | 100.25 | - |
| EOGNBIFH_71 | 15635 | 16366 | STR_RS05260 | 0.0 | Capsule | Immune modulation | 98.36 | 100.00 | WP_011227248 |
| EOGNBIFH_71 | 14175 | 14924 | STR_RS05250 | 0.0 | Capsule | Immune modulation | 98.27 | 100.00 | WP_011227246 |
| EOGNBIFH_71 | 16367 | 17821 | STU_RS14650 | 0.0 | Capsule | Immune modulation | 98.21 | 100.00 | WP_011226049 |
| EOGNBIFH_71 | 14189 | 14924 | STU_RS14635 | 0.0 | Capsule | Immune modulation | 98.10 | 99.33 | WP_011226046 |
| EOGNBIFH_79 | 10437 | 11708 | STU_RS16265 | 0.0 | Capsule | Immune modulation | 97.48 | 99.76 | WP_011226331 |
| EOGNBIFH_71 | 16367 | 17821 | STER_RS05320 | 0.0 | Capsule | Immune modulation | 96.65 | 99.79 | WP_011681177 |
| EOGNBIFH_120 | 33279 | 38173 | SAG_RS09105 | 0.0 | Agglutinin receptor | Adherence | 92.87 | 99.98 | WP_000167699 |
| EOGNBIFH_120 | 33279 | 38221 | SSU98_0978 | 0.0 | Agglutinin receptor | Adherence | 92.82 | 99.78 | YP_001200536 |
| EOGNBIFH_120 | 33279 | 38221 | SSU05_0965 | 0.0 | Agglutinin receptor | Adherence | 92.80 | 99.78 | YP_001198331 |
| EOGNBIFH_71 | 14934 | 15626 | STER_RS05310 | 0.0 | Capsule | Immune modulation | 89.90 | 100.00 | WP_011681175 |
| EOGNBIFH_71 | 14934 | 15626 | STU_RS14640 | 0.0 | Capsule | Immune modulation | 89.75 | 100.00 | WP_011226047 |
| EOGNBIFH_71 | 14934 | 15626 | STR_RS05255 | 0.0 | Capsule | Immune modulation | 89.47 | 100.00 | WP_011227247 |
| EOGNBIFH_84 | 49411 | 50714 | eno | 0.0 | Streptococcal enolase | Exoenzyme | 88.10 | 99.46 | WP_000022832 |
| EOGNBIFH_76 | 90 | 1100 | plr/gapA | 0.0 | Streptococcal plasmin receptor/GAPDH | Adherence | 86.54 | 99.41 | WP_002986042 |
| EOGNBIFH_64 | 4785 | 6068 | tig/ropA | 0.0 | Trigger factor | Stress survival | 80.73 | 99.77 | WP_000107753 |
| EOGNBIFH_65 | 7523 | 8569 | rfbB | 0.0 | Capsule | Immune modulation | 80.61 | 100.00 | WP_009659423 |
BLASTN v2.16.0 (Database: VFDB, Dec. 2024 release)
VirulenceFinder
| Query ID | Begin | End | Database | Virulence factor | Protein function | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
VirulenceFinder v2.0. 4 (Database: virulencefinder_db, Feb . 2024 release)
Pathogenic genes
PHI-base
| Query ID | qstart | qend | Gene name | e-value | Function | Identity | Coverage | Gene ID |
|---|---|---|---|---|---|---|---|---|
| EOGNBIFH_129 | 18067 | 19050 | ldh(Sp_1220) | 0.0 | L-lactate dehydrogenase | 94.82 | 100.00 | AAK75326 |
| EOGNBIFH_80 | 6709 | 7782 | MntE | 0.0 | manganese homeostasis | 94.41 | 99.72 | ABF32167 |
| EOGNBIFH_120 | 38194 | 33284 | B9H01_RS04765 | 0.0 | glucan-binding protein | 93.40 | 99.63 | AUS90958 |
| EOGNBIFH_84 | 134399 | 133431 | spr0084 | 0.0 | pathogenitcity related | 93.19 | 98.48 | AAK98888 |
| EOGNBIFH_68 | 15570 | 13267 | pfl2(Sp_0459) | 0.0 | formate acetyltransferase | 92.97 | 99.22 | AAK74619 |
| EOGNBIFH_66 | 13140 | 11659 | SPD_0310 | 0.0 | UPF0371 protein SPD_0310 | 92.31 | 100.00 | ABJ54480 |
| EOGNBIFH_135 | 6144 | 8390 | metE | 0.0 | methionine biosynthesis enzymes | 91.72 | 100.00 | AAK74738 |
| EOGNBIFH_30 | 12609 | 13607 | recA | 0.0 | DNA recombination and repair | 91.29 | 85.82 | AAL00560 |
| EOGNBIFH_36 | 3366 | 4337 | prsA2 | 0.0 | ribose-phosphate pyrophosphokinase | 90.12 | 100.00 | ABF36968 |
| EOGNBIFH_73 | 19993 | 18842 | potA | 0.0 | ABC transporter ATP-binding protein-spermidine/putrescine transport | 89.32 | 99.74 | AAL00050 |
| EOGNBIFH_79 | 28632 | 26644 | uvrB | 0.0 | excinuclease ABC, B subunit | 88.99 | 100.00 | AE014259_2 |
| EOGNBIFH_129 | 1868 | 138 | ptsI | 0.0 | phosphoenolpyruvate-protein phosphotransferase | 88.04 | 100.00 | AAK34199 |
| EOGNBIFH_125 | 69862 | 68384 | IMPDH | 0.0 | inosine-5'-monophosphate dehydrogenase | 87.22 | 100.00 | ADE32434 |
| EOGNBIFH_84 | 50714 | 49413 | Eno | 0.0 | enolase | 86.21 | 99.77 | ABP90468 |
| EOGNBIFH_125 | 54673 | 52781 | gidA | 0.0 | tRNA uridine 5-carboxymethylaminomethyl modification enzyme | 86.05 | 98.90 | ABP91129 |
| EOGNBIFH_135 | 11315 | 9606 | PGM | 0.0 | phosphoglucomutase | 83.71 | 99.65 | ACH87041 |
| EOGNBIFH_75 | 2070 | 1060 | pdh | 0.0 | pyruvate dehydrogenase | 83.09 | 99.70 | ABP91006 |
| EOGNBIFH_74 | 30234 | 31595 | mnmE | 0.0 | central tRNA-modifying GTPase | 82.24 | 99.56 | ABP90420 |
| EOGNBIFH_102 | 4718 | 6610 | PepO | 0.0 | endopeptidase | 80.19 | 100.00 | ABF32980 |
| EOGNBIFH_84 | 65149 | 64259 | bglB | 1.06e-179 | putative phospho--glucosidase | 88.89 | 99.66 | AAK33487 |
| EOGNBIFH_8 | 3943 | 3005 | SP_0676 | 5.99e-169 | transcription facot | 81.15 | 97.20 | AAK74821 |
| EOGNBIFH_135 | 8582 | 9439 | metF | 1.40e-166 | methionine biosynthesis enzymes | 86.36 | 99.31 | AAK74739 |
| EOGNBIFH_133 | 24440 | 23736 | covR | 1.26e-132 | responder protein | 85.53 | 100.00 | AAK71319 |
| EOGNBIFH_67 | 22941 | 23612 | rr01 | 6.85e-126 | response regulator | 83.93 | 99.56 | CAB54566 |
| EOGNBIFH_133 | 24440 | 23736 | walR | 5.31e-123 | DNA-binding response regulator | 82.13 | 100.00 | ANC99504 |
| EOGNBIFH_134 | 7742 | 7056 | CovR | 1.31e-119 | serves to repress GAS virulence factor-encoding genes | 80.79 | 100.00 | ACE75886 |
| EOGNBIFH_135 | 15269 | 15937 | CiaR | 1.86e-119 | two-component response regulator | 84.31 | 99.55 | AAK74935 |
| EOGNBIFH_135 | 15269 | 15940 | ciaR | 1.83e-117 | two component system response regulator | 82.14 | 99.12 | AIK75708 |
| EOGNBIFH_30 | 13883 | 14257 | SpxA2 | 8.91e-72 | transcriptional regulator | 91.20 | 94.70 | ERL21461 |
| EOGNBIFH_74 | 18875 | 18474 | SpxA1 | 1.10e-67 | transcriptional regulator | 80.60 | 100.00 | ERL19273 |
| EOGNBIFH_55 | 25495 | 25208 | spr0479 | 1.31e-48 | essential gene | 85.42 | 98.97 | AAK99283 |
| EOGNBIFH_103 | 18148 | 17894 | spr1327 | 1.11e-45 | essential gene | 95.29 | 100.00 | AAL00131 |
| EOGNBIFH_125 | 10152 | 10415 | spr0175 | 4.62e-42 | pathogenitcity related | 84.09 | 100.00 | AAK98979 |
| EOGNBIFH_125 | 10979 | 11245 | spr0177 | 8.16e-34 | essential gene | 84.27 | 88.12 | AAK98981 |
| EOGNBIFH_64 | 6226 | 6726 | RopE (M5005_Spy_1611) | 1.82e-76 | probable DNA-directed RNA polymerase subunit delta | 81.44 | 87.43 | AAK34603 |
| EOGNBIFH_68 | 15570 | 13273 | PFL (B9H01_RS01125) | 0.0 | formate C-acetyltransferase | 82.94 | 98.08 | MYN69560 |
| EOGNBIFH_120 | 3571 | 2375 | AUS90997 (B9H01_RS07385) | 0.0 | site-specific integrase | 97.74 | 100.00 | AUS90997 |
| EOGNBIFH_102 | 19190 | 20209 | ilvC (SPD_0406) | 0.0 | ketol-acid reductoisomerase (NADP(+)) | 96.47 | 100.00 | ABJ55451 |
BLASTX v2.16.0 (Database: PHI base v4.16, May. 2024 release)
Plasmid
PlasmidFinder
| Query ID | Begin | End | Plasmid | Query / Template | Identity | Accession no. |
|---|---|---|---|---|---|---|
| EOGNBIFH_86 | 5184 | 6329 | rep33 | 1157 / 1155 | 82.71 | X92946 |
PlasmidFinder v 2.1.6 (Database: plasmidfinder_db v 2.2.0 , Nov. 2024 release)
PlasmidHunter
| Query ID | Prediction | Chromosome | Plasmid |
|---|---|---|---|
| EOGNBIFH_1 | 0.0 | 1.0 | 0.0 |
| EOGNBIFH_2 | 0.0 | 1.0 | 0.0 |
| EOGNBIFH_3 | 1.0 | 0.0 | 1.0 |
| EOGNBIFH_4 | 0.0 | 1.0 | 0.0 |
| EOGNBIFH_5 | 1.0 | 0.0 | 1.0 |
| EOGNBIFH_6 | 1.0 | 0.0 | 1.0 |
| EOGNBIFH_7 | 0.0 | 1.0 | 0.0 |
| EOGNBIFH_8 | 0.0 | 1.0 | 0.0 |
| EOGNBIFH_9 | 1.0 | 0.0 | 1.0 |
| EOGNBIFH_11 | 0.0 | 1.0 | 0.0 |
| EOGNBIFH_17 | 1.0 | 0.0 | 1.0 |
| EOGNBIFH_18 | 0.0 | 1.0 | 0.0 |
| EOGNBIFH_21 | 0.0 | 1.0 | 0.0 |
| EOGNBIFH_22 | 0.0 | 1.0 | 0.0 |
| EOGNBIFH_24 | 1.0 | 0.0 | 1.0 |
| EOGNBIFH_25 | 0.0 | 1.0 | 0.0 |
| EOGNBIFH_26 | 1.0 | 0.0 | 1.0 |
| EOGNBIFH_27 | 0.0 | 1.0 | 0.0 |
| EOGNBIFH_30 | 0.0 | 1.0 | 0.0 |
| EOGNBIFH_32 | 1.0 | 0.0 | 1.0 |
| EOGNBIFH_33 | 1.0 | 0.0 | 1.0 |
| EOGNBIFH_35 | 1.0 | 0.0 | 1.0 |
| EOGNBIFH_36 | 0.0 | 1.0 | 0.0 |
| EOGNBIFH_44 | 0.0 | 1.0 | 0.0 |
| EOGNBIFH_46 | 0.0 | 1.0 | 0.0 |
| EOGNBIFH_55 | 0.0 | 1.0 | 0.0 |
| EOGNBIFH_60 | 0.0 | 1.0 | 0.0 |
| EOGNBIFH_61 | 0.0 | 1.0 | 0.0 |
| EOGNBIFH_63 | 1.0 | 0.0 | 1.0 |
| EOGNBIFH_64 | 0.0 | 1.0 | 0.0 |
| EOGNBIFH_65 | 0.0 | 1.0 | 0.0 |
| EOGNBIFH_66 | 0.0 | 1.0 | 0.0 |
| EOGNBIFH_67 | 0.0 | 1.0 | 0.0 |
| EOGNBIFH_68 | 0.0 | 1.0 | 0.0 |
| EOGNBIFH_69 | 0.0 | 1.0 | 0.0 |
| EOGNBIFH_70 | 0.0 | 1.0 | 0.0 |
| EOGNBIFH_71 | 0.0 | 1.0 | 0.0 |
| EOGNBIFH_72 | 0.0 | 1.0 | 0.0 |
| EOGNBIFH_73 | 0.0 | 1.0 | 0.0 |
| EOGNBIFH_74 | 0.0 | 1.0 | 0.0 |
| EOGNBIFH_75 | 0.0 | 1.0 | 0.0 |
| EOGNBIFH_76 | 0.0 | 1.0 | 0.0 |
| EOGNBIFH_77 | 0.0 | 1.0 | 0.0 |
| EOGNBIFH_78 | 0.0 | 1.0 | 0.0 |
| EOGNBIFH_79 | 0.0 | 1.0 | 0.0 |
| EOGNBIFH_80 | 0.0 | 1.0 | 0.0 |
| EOGNBIFH_81 | 0.0 | 1.0 | 0.0 |
| EOGNBIFH_82 | 1.0 | 0.0 | 1.0 |
| EOGNBIFH_83 | 1.0 | 0.0 | 1.0 |
| EOGNBIFH_84 | 0.0 | 1.0 | 0.0 |
| EOGNBIFH_85 | 1.0 | 0.0 | 1.0 |
| EOGNBIFH_86 | 1.0 | 0.0 | 1.0 |
| EOGNBIFH_88 | 0.0 | 1.0 | 0.0 |
| EOGNBIFH_89 | 0.0 | 1.0 | 0.0 |
| EOGNBIFH_92 | 0.0 | 1.0 | 0.0 |
| EOGNBIFH_93 | 0.0 | 1.0 | 0.0 |
| EOGNBIFH_94 | 0.0 | 1.0 | 0.0 |
| EOGNBIFH_95 | 0.0 | 1.0 | 0.0 |
| EOGNBIFH_96 | 0.0 | 1.0 | 0.0 |
| EOGNBIFH_97 | 0.0 | 1.0 | 0.0 |
| EOGNBIFH_101 | 0.0 | 1.0 | 0.0 |
| EOGNBIFH_102 | 0.0 | 1.0 | 0.0 |
| EOGNBIFH_103 | 0.0 | 1.0 | 0.0 |
| EOGNBIFH_105 | 0.0 | 1.0 | 0.0 |
| EOGNBIFH_115 | 1.0 | 0.0 | 1.0 |
| EOGNBIFH_120 | 0.0 | 1.0 | 0.0 |
| EOGNBIFH_121 | 0.0 | 1.0 | 0.0 |
| EOGNBIFH_125 | 0.0 | 1.0 | 0.0 |
| EOGNBIFH_127 | 0.0 | 1.0 | 0.0 |
| EOGNBIFH_128 | 0.0 | 1.0 | 0.0 |
| EOGNBIFH_129 | 0.0 | 1.0 | 0.0 |
| EOGNBIFH_130 | 1.0 | 0.0 | 1.0 |
| EOGNBIFH_131 | 0.0 | 1.0 | 0.0 |
| EOGNBIFH_133 | 0.0 | 1.0 | 0.0 |
| EOGNBIFH_134 | 0.0 | 1.0 | 0.0 |
| EOGNBIFH_135 | 0.0 | 1.0 | 0.0 |
| EOGNBIFH_136 | 0.0 | 1.0 | 0.0 |
PlasmidHunter v 1.4.5 (Database: May. 2024 release)
Prophage
Phigaro
| Query ID | Begin | End | Transposable | Taxonomy | pVOGs |
|---|---|---|---|---|---|
| No hit found | |||||
Phigaro v2.4.0 (Database: Jan. 2024 release)