Probiotic potential risk score
| ARGs | VFs | PGs | PPRS |
|---|---|---|---|
| 0 | 26 | 33 | 42.01 |
PPRS is classified as low-risk (≤4), medium-risk (4-6), and high-risk (≥6).
Antibiotic resistance genes
Comprehensive Antibiotic Resistance Database (CARD)
| Query ID | Begin | End | ARO name | ARO accession | CARD name | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
RGI v6.0.3 (Database: CARD Variants v4.0.2, Nov. 2023 release)
ResFinder
| Query ID | Begin | End | Resistance gene | Phenotype | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|
| No hit found | |||||||
ResFinder v4.6.0 (Database: resfinder_db, Aug. 2024 release)
AMRFinderPlus
| Query ID | Begin | End | Gene symbol | Sequence name | Method | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
AMRFinderPlus v4.0.3 (Database: Oct. 2024 release)
Virulence factors
Virulence Factor Database (VFDB)
| Query ID | qstart | qend | Gene name | e-value | VF name | VF category | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|---|
| FKPILCKI_38 | 171 | 1010 | cbpD | 0.0 | Autolysin | Exoenzyme | 100.00 | 100.00 | WP_011226733 |
| FKPILCKI_61 | 97153 | 97746 | STR_RS05880 | 0.0 | Capsule | Immune modulation | 99.83 | 100.00 | WP_011226149 |
| FKPILCKI_25 | 74181 | 75137 | STU_RS16250 | 0.0 | Capsule | Immune modulation | 99.79 | 100.00 | WP_011226328 |
| FKPILCKI_25 | 75121 | 75930 | STU_RS16245 | 0.0 | Capsule | Immune modulation | 99.75 | 100.00 | WP_002948020 |
| FKPILCKI_61 | 97153 | 97746 | STER_RS06030 | 0.0 | Capsule | Immune modulation | 99.66 | 100.00 | WP_011226149 |
| FKPILCKI_61 | 97153 | 97746 | STU_RS15260 | 0.0 | Capsule | Immune modulation | 99.66 | 100.00 | WP_011226149 |
| FKPILCKI_25 | 73036 | 74184 | STU_RS16255 | 0.0 | Capsule | Immune modulation | 99.65 | 100.00 | WP_041828290 |
| FKPILCKI_25 | 68689 | 69540 | rfbD | 0.0 | Capsule | Immune modulation | 99.53 | 100.00 | WP_014621820 |
| FKPILCKI_25 | 77155 | 78210 | STU_RS16235 | 0.0 | Capsule | Immune modulation | 99.53 | 100.00 | WP_002948022 |
| FKPILCKI_54 | 11043 | 12701 | fbp54 | 0.0 | FBPs | Adherence | 99.52 | 100.00 | WP_011227179 |
| FKPILCKI_25 | 75930 | 77135 | STU_RS16240 | 0.0 | Capsule | Immune modulation | 99.50 | 100.00 | WP_011226326 |
| FKPILCKI_25 | 78207 | 79991 | STU_RS16230 | 0.0 | Capsule | Immune modulation | 99.44 | 100.00 | WP_011226325 |
| FKPILCKI_41 | 13959 | 14558 | STR_RS05245 | 0.0 | Capsule | Immune modulation | 99.33 | 100.00 | WP_196767671 |
| FKPILCKI_61 | 97746 | 98615 | rfbA | 0.0 | Capsule | Immune modulation | 99.08 | 100.00 | WP_011681286 |
| FKPILCKI_64 | 597 | 2012 | STER_RS05250 | 0.0 | Capsule | Immune modulation | 99.01 | 100.00 | WP_011681165 |
| FKPILCKI_61 | 52627 | 53417 | cshA | 0.0 | Cell surface hydrophobicity proteins | Adherence | 98.99 | 100.00 | - |
| FKPILCKI_25 | 71917 | 72927 | STU_RS16260 | 0.0 | Capsule | Immune modulation | 98.91 | 100.00 | WP_011226330 |
| FKPILCKI_18 | 25631 | 26392 | srtA | 0.0 | Sortase A | Exoenzyme | 98.82 | 100.00 | - |
| FKPILCKI_41 | 16894 | 18348 | STU_RS14650 | 0.0 | Capsule | Immune modulation | 98.76 | 100.00 | WP_011226049 |
| FKPILCKI_41 | 16894 | 18348 | STR_RS05265 | 0.0 | Capsule | Immune modulation | 98.62 | 100.00 | WP_041827043 |
| FKPILCKI_41 | 12835 | 13794 | STR_RS05240 | 0.0 | Capsule | Immune modulation | 98.23 | 100.00 | WP_041827042 |
| FKPILCKI_25 | 70643 | 71917 | STU_RS16265 | 0.0 | Capsule | Immune modulation | 98.20 | 100.00 | WP_011226331 |
| FKPILCKI_41 | 14710 | 15445 | STER_RS05305 | 0.0 | Capsule | Immune modulation | 97.96 | 99.33 | WP_011681174 |
| FKPILCKI_41 | 14710 | 15445 | STU_RS14635 | 0.0 | Capsule | Immune modulation | 97.83 | 99.33 | WP_011226046 |
| FKPILCKI_41 | 16162 | 16893 | STER_RS05315 | 0.0 | Capsule | Immune modulation | 97.68 | 100.00 | WP_011681176 |
| FKPILCKI_41 | 14696 | 15445 | STR_RS05250 | 0.0 | Capsule | Immune modulation | 97.47 | 100.00 | WP_011227246 |
| FKPILCKI_41 | 16162 | 16893 | STU_RS14645 | 0.0 | Capsule | Immune modulation | 97.27 | 100.00 | WP_011226048 |
| FKPILCKI_41 | 16894 | 18348 | STER_RS05320 | 0.0 | Capsule | Immune modulation | 97.06 | 99.79 | WP_011681177 |
| FKPILCKI_41 | 16162 | 16893 | STR_RS05260 | 0.0 | Capsule | Immune modulation | 96.86 | 100.00 | WP_011227248 |
| FKPILCKI_41 | 15455 | 16136 | STU_RS14640 | 0.0 | Capsule | Immune modulation | 93.25 | 98.41 | WP_011226047 |
| FKPILCKI_41 | 15455 | 16136 | STR_RS05255 | 0.0 | Capsule | Immune modulation | 92.96 | 98.41 | WP_011227247 |
| FKPILCKI_70 | 106817 | 108120 | eno | 0.0 | Streptococcal enolase | Exoenzyme | 87.86 | 99.54 | WP_000022832 |
| FKPILCKI_47 | 270 | 1280 | plr/gapA | 0.0 | Streptococcal plasmin receptor/GAPDH | Adherence | 86.92 | 99.51 | WP_002986042 |
| FKPILCKI_41 | 15455 | 16136 | STER_RS05310 | 0.0 | Capsule | Immune modulation | 85.92 | 98.41 | WP_011681175 |
| FKPILCKI_51 | 62913 | 64196 | tig/ropA | 0.0 | Trigger factor | Stress survival | 80.58 | 99.77 | WP_000107753 |
| FKPILCKI_61 | 95678 | 96724 | rfbB | 0.0 | Capsule | Immune modulation | 80.33 | 100.00 | WP_009659423 |
BLASTN v2.16.0 (Database: VFDB, Dec. 2024 release)
VirulenceFinder
| Query ID | Begin | End | Database | Virulence factor | Protein function | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
VirulenceFinder v2.0. 4 (Database: virulencefinder_db, Feb . 2024 release)
Pathogenic genes
PHI-base
| Query ID | qstart | qend | Gene name | e-value | Function | Identity | Coverage | Gene ID |
|---|---|---|---|---|---|---|---|---|
| FKPILCKI_18 | 22944 | 21961 | ldh(Sp_1220) | 0.0 | L-lactate dehydrogenase | 94.82 | 100.00 | AAK75326 |
| FKPILCKI_70 | 208776 | 209849 | MntE | 0.0 | manganese homeostasis | 94.41 | 99.72 | ABF32167 |
| FKPILCKI_19 | 40709 | 43012 | pfl2(Sp_0459) | 0.0 | formate acetyltransferase | 93.10 | 99.22 | AAK74619 |
| FKPILCKI_70 | 24608 | 25576 | spr0084 | 0.0 | pathogenitcity related | 92.57 | 98.48 | AAK98888 |
| FKPILCKI_2 | 9484 | 8003 | SPD_0310 | 0.0 | UPF0371 protein SPD_0310 | 92.11 | 100.00 | ABJ54480 |
| FKPILCKI_46 | 11334 | 9088 | metE | 0.0 | methionine biosynthesis enzymes | 91.99 | 100.00 | AAK74738 |
| FKPILCKI_57 | 1892 | 894 | recA | 0.0 | DNA recombination and repair | 91.29 | 85.82 | AAL00560 |
| FKPILCKI_36 | 15297 | 14326 | prsA2 | 0.0 | ribose-phosphate pyrophosphokinase | 90.12 | 100.00 | ABF36968 |
| FKPILCKI_25 | 25713 | 26864 | potA | 0.0 | ABC transporter ATP-binding protein-spermidine/putrescine transport | 89.32 | 99.74 | AAL00050 |
| FKPILCKI_25 | 53719 | 55707 | uvrB | 0.0 | excinuclease ABC, B subunit | 88.99 | 100.00 | AE014259_2 |
| FKPILCKI_61 | 119763 | 118033 | ptsI | 0.0 | phosphoenolpyruvate-protein phosphotransferase | 87.69 | 100.00 | AAK34199 |
| FKPILCKI_34 | 63338 | 61860 | IMPDH | 0.0 | inosine-5'-monophosphate dehydrogenase | 87.63 | 100.00 | ADE32434 |
| FKPILCKI_70 | 106817 | 108118 | Eno | 0.0 | enolase | 86.21 | 99.77 | ABP90468 |
| FKPILCKI_34 | 48143 | 46251 | gidA | 0.0 | tRNA uridine 5-carboxymethylaminomethyl modification enzyme | 86.05 | 98.90 | ABP91129 |
| FKPILCKI_46 | 6162 | 7871 | PGM | 0.0 | phosphoglucomutase | 83.89 | 99.65 | ACH87041 |
| FKPILCKI_45 | 55198 | 54188 | pdh | 0.0 | pyruvate dehydrogenase | 83.09 | 99.70 | ABP91006 |
| FKPILCKI_23 | 43857 | 45218 | mnmE | 0.0 | central tRNA-modifying GTPase | 82.02 | 99.56 | ABP90420 |
| FKPILCKI_45 | 4931 | 6823 | PepO | 0.0 | endopeptidase | 80.03 | 100.00 | ABF32980 |
| FKPILCKI_70 | 92385 | 93275 | bglB | 3.49e-179 | putative phospho--glucosidase | 88.55 | 99.66 | AAK33487 |
| FKPILCKI_12 | 13343 | 12405 | SP_0676 | 2.41e-169 | transcription facot | 81.47 | 97.20 | AAK74821 |
| FKPILCKI_46 | 8896 | 8039 | metF | 2.02e-166 | methionine biosynthesis enzymes | 86.01 | 99.31 | AAK74739 |
| FKPILCKI_61 | 24995 | 24291 | covR | 4.72e-132 | responder protein | 85.53 | 100.00 | AAK71319 |
| FKPILCKI_2 | 28454 | 29125 | rr01 | 1.72e-126 | response regulator | 84.38 | 99.56 | CAB54566 |
| FKPILCKI_61 | 24995 | 24291 | walR | 2.23e-122 | DNA-binding response regulator | 81.70 | 100.00 | ANC99504 |
| FKPILCKI_46 | 2208 | 1540 | CiaR | 5.35e-122 | two-component response regulator | 85.65 | 99.55 | AAK74935 |
| FKPILCKI_46 | 2208 | 1537 | ciaR | 7.61e-120 | two component system response regulator | 83.48 | 99.12 | AIK75708 |
| FKPILCKI_37 | 10308 | 9622 | CovR | 5.77e-119 | serves to repress GAS virulence factor-encoding genes | 80.35 | 100.00 | ACE75886 |
| FKPILCKI_57 | 618 | 244 | SpxA2 | 7.56e-72 | transcriptional regulator | 91.20 | 94.70 | ERL21461 |
| FKPILCKI_23 | 32500 | 32099 | SpxA1 | 1.03e-67 | transcriptional regulator | 80.60 | 100.00 | ERL19273 |
| FKPILCKI_31 | 25422 | 25135 | spr0479 | 3.07e-49 | essential gene | 86.46 | 98.97 | AAK99283 |
| FKPILCKI_3 | 9897 | 9643 | spr1327 | 1.05e-45 | essential gene | 95.29 | 100.00 | AAL00131 |
| FKPILCKI_34 | 14605 | 14868 | spr0175 | 4.31e-42 | pathogenitcity related | 84.09 | 100.00 | AAK98979 |
| FKPILCKI_34 | 15408 | 15698 | spr0177 | 2.53e-37 | essential gene | 81.00 | 98.02 | AAK98981 |
| FKPILCKI_51 | 62755 | 62255 | RopE (M5005_Spy_1611) | 1.76e-76 | probable DNA-directed RNA polymerase subunit delta | 81.44 | 87.43 | AAK34603 |
| FKPILCKI_19 | 40709 | 43006 | PFL (B9H01_RS01125) | 0.0 | formate C-acetyltransferase | 83.07 | 98.08 | MYN69560 |
| FKPILCKI_45 | 19331 | 20350 | ilvC (SPD_0406) | 0.0 | ketol-acid reductoisomerase (NADP(+)) | 96.47 | 100.00 | ABJ55451 |
BLASTX v2.16.0 (Database: PHI base v4.16, May. 2024 release)
Plasmid
PlasmidFinder
| Query ID | Begin | End | Plasmid | Query / Template | Identity | Accession no. |
|---|---|---|---|---|---|---|
| No hit found | ||||||
PlasmidFinder v 2.1.6 (Database: plasmidfinder_db v 2.2.0 , Nov. 2024 release)
PlasmidHunter
| Query ID | Prediction | Chromosome | Plasmid |
|---|---|---|---|
| FKPILCKI_2 | 0.0 | 1.0 | 0.0 |
| FKPILCKI_3 | 0.0 | 1.0 | 0.0 |
| FKPILCKI_4 | 0.0 | 1.0 | 0.0 |
| FKPILCKI_5 | 0.0 | 1.0 | 0.0 |
| FKPILCKI_8 | 0.0 | 1.0 | 0.0 |
| FKPILCKI_9 | 0.0 | 1.0 | 0.0 |
| FKPILCKI_10 | 0.0 | 1.0 | 0.0 |
| FKPILCKI_12 | 0.0 | 1.0 | 0.0 |
| FKPILCKI_13 | 0.0 | 1.0 | 0.0 |
| FKPILCKI_15 | 0.0 | 1.0 | 0.0 |
| FKPILCKI_18 | 0.0 | 1.0 | 0.0 |
| FKPILCKI_19 | 0.0 | 1.0 | 0.0 |
| FKPILCKI_20 | 0.0 | 1.0 | 0.0 |
| FKPILCKI_21 | 0.0 | 1.0 | 0.0 |
| FKPILCKI_23 | 0.0 | 1.0 | 0.0 |
| FKPILCKI_24 | 0.0 | 1.0 | 0.0 |
| FKPILCKI_25 | 0.0 | 1.0 | 0.0 |
| FKPILCKI_27 | 0.0 | 1.0 | 0.0 |
| FKPILCKI_28 | 0.0 | 1.0 | 0.0 |
| FKPILCKI_30 | 0.0 | 1.0 | 0.0 |
| FKPILCKI_31 | 0.0 | 1.0 | 0.0 |
| FKPILCKI_32 | 0.0 | 1.0 | 0.0 |
| FKPILCKI_34 | 0.0 | 1.0 | 0.0 |
| FKPILCKI_35 | 0.0 | 1.0 | 0.0 |
| FKPILCKI_36 | 0.0 | 1.0 | 0.0 |
| FKPILCKI_37 | 0.0 | 1.0 | 0.0 |
| FKPILCKI_38 | 0.0 | 1.0 | 0.0 |
| FKPILCKI_39 | 0.0 | 1.0 | 0.0 |
| FKPILCKI_40 | 0.0 | 1.0 | 0.0 |
| FKPILCKI_41 | 0.0 | 1.0 | 0.0 |
| FKPILCKI_42 | 0.0 | 1.0 | 0.0 |
| FKPILCKI_44 | 0.0 | 1.0 | 0.0 |
| FKPILCKI_45 | 0.0 | 1.0 | 0.0 |
| FKPILCKI_46 | 0.0 | 1.0 | 0.0 |
| FKPILCKI_47 | 0.0 | 1.0 | 0.0 |
| FKPILCKI_48 | 0.0 | 1.0 | 0.0 |
| FKPILCKI_49 | 0.0 | 1.0 | 0.0 |
| FKPILCKI_50 | 0.0 | 1.0 | 0.0 |
| FKPILCKI_51 | 0.0 | 1.0 | 0.0 |
| FKPILCKI_52 | 0.0 | 1.0 | 0.0 |
| FKPILCKI_53 | 0.0 | 1.0 | 0.0 |
| FKPILCKI_54 | 0.0 | 1.0 | 0.0 |
| FKPILCKI_55 | 0.0 | 1.0 | 0.0 |
| FKPILCKI_57 | 0.0 | 1.0 | 0.0 |
| FKPILCKI_59 | 0.0 | 1.0 | 0.0 |
| FKPILCKI_60 | 1.0 | 0.0 | 1.0 |
| FKPILCKI_61 | 0.0 | 1.0 | 0.0 |
| FKPILCKI_62 | 1.0 | 0.0 | 1.0 |
| FKPILCKI_63 | 1.0 | 0.0 | 1.0 |
| FKPILCKI_64 | 0.0 | 1.0 | 0.0 |
| FKPILCKI_65 | 0.0 | 1.0 | 0.0 |
| FKPILCKI_67 | 0.0 | 1.0 | 0.0 |
| FKPILCKI_68 | 1.0 | 0.0 | 1.0 |
| FKPILCKI_70 | 0.0 | 1.0 | 0.0 |
| FKPILCKI_79 | 0.0 | 1.0 | 0.0 |
PlasmidHunter v 1.4.5 (Database: May. 2024 release)
Prophage
Phigaro
| Query ID | Begin | End | Transposable | Taxonomy | pVOGs |
|---|---|---|---|---|---|
| No hit found | |||||
Phigaro v2.4.0 (Database: Jan. 2024 release)