Probiotic potential risk score
| ARGs | VFs | PGs | PPRS |
|---|---|---|---|
| 0 | 27 | 32 | 41.87 |
PPRS is classified as low-risk (≤4), medium-risk (4-6), and high-risk (≥6).
Antibiotic resistance genes
Comprehensive Antibiotic Resistance Database (CARD)
| Query ID | Begin | End | ARO name | ARO accession | CARD name | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
RGI v6.0.3 (Database: CARD Variants v4.0.2, Nov. 2023 release)
ResFinder
| Query ID | Begin | End | Resistance gene | Phenotype | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|
| No hit found | |||||||
ResFinder v4.6.0 (Database: resfinder_db, Aug. 2024 release)
AMRFinderPlus
| Query ID | Begin | End | Gene symbol | Sequence name | Method | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
AMRFinderPlus v4.0.3 (Database: Oct. 2024 release)
Virulence factors
Virulence Factor Database (VFDB)
| Query ID | qstart | qend | Gene name | e-value | VF name | VF category | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|---|
| ECNIGJDD_48 | 9589 | 10458 | rfbA | 0.0 | Capsule | Immune modulation | 100.00 | 100.00 | WP_011681286 |
| ECNIGJDD_48 | 8996 | 9589 | STER_RS06030 | 0.0 | Capsule | Immune modulation | 100.00 | 100.00 | WP_011226149 |
| ECNIGJDD_50 | 22129 | 23388 | STER_RS07100 | 0.0 | Capsule | Immune modulation | 100.00 | 100.00 | WP_011681445 |
| ECNIGJDD_50 | 18331 | 19107 | STER_RS07075 | 0.0 | Capsule | Immune modulation | 99.87 | 100.00 | WP_011681440 |
| ECNIGJDD_48 | 8996 | 9589 | STR_RS05880 | 0.0 | Capsule | Immune modulation | 99.83 | 100.00 | WP_011226149 |
| ECNIGJDD_50 | 17064 | 18212 | STER_RS07070 | 0.0 | Capsule | Immune modulation | 99.74 | 100.00 | WP_011681439 |
| ECNIGJDD_48 | 8996 | 9589 | STU_RS15260 | 0.0 | Capsule | Immune modulation | 99.66 | 100.00 | WP_011226149 |
| ECNIGJDD_116 | 17714 | 18857 | cshA | 0.0 | Cell surface hydrophobicity proteins | Adherence | 99.65 | 100.00 | - |
| ECNIGJDD_50 | 21156 | 22132 | STER_RS07095 | 0.0 | Capsule | Immune modulation | 99.59 | 99.90 | WP_011681444 |
| ECNIGJDD_50 | 16126 | 17067 | STER_RS07065 | 0.0 | Capsule | Immune modulation | 99.58 | 100.00 | WP_011681438 |
| ECNIGJDD_45 | 2432 | 4090 | fbp54 | 0.0 | FBPs | Adherence | 99.52 | 100.00 | WP_011227179 |
| ECNIGJDD_50 | 15320 | 16126 | STER_RS07060 | 0.0 | Capsule | Immune modulation | 99.50 | 100.00 | WP_011681437 |
| ECNIGJDD_50 | 17064 | 18212 | STR_RS06910 | 0.0 | Capsule | Immune modulation | 99.48 | 100.00 | WP_011227431 |
| ECNIGJDD_50 | 16126 | 17067 | STR_RS06905 | 0.0 | Capsule | Immune modulation | 99.47 | 100.00 | WP_011227430 |
| ECNIGJDD_50 | 10967 | 12712 | STER_RS07045 | 0.0 | Capsule | Immune modulation | 99.37 | 100.00 | WP_011681434 |
| ECNIGJDD_50 | 19453 | 20168 | STER_RS07085 | 0.0 | Capsule | Immune modulation | 99.30 | 99.86 | WP_011681442 |
| ECNIGJDD_50 | 20170 | 21138 | STER_RS07090 | 0.0 | Capsule | Immune modulation | 99.28 | 100.00 | WP_011681443 |
| ECNIGJDD_50 | 15320 | 16126 | STR_RS06900 | 0.0 | Capsule | Immune modulation | 99.26 | 100.00 | WP_011227429 |
| ECNIGJDD_48 | 44356 | 45117 | srtA | 0.0 | Sortase A | Exoenzyme | 99.08 | 100.00 | - |
| ECNIGJDD_83 | 3532 | 4263 | STER_RS05315 | 0.0 | Capsule | Immune modulation | 98.50 | 100.00 | WP_011681176 |
| ECNIGJDD_83 | 3532 | 4263 | STU_RS14645 | 0.0 | Capsule | Immune modulation | 98.50 | 100.00 | WP_011226048 |
| ECNIGJDD_50 | 23507 | 24358 | rfbD | 0.0 | Capsule | Immune modulation | 98.36 | 100.00 | WP_014621820 |
| ECNIGJDD_83 | 3532 | 4263 | STR_RS05260 | 0.0 | Capsule | Immune modulation | 98.36 | 100.00 | WP_011227248 |
| ECNIGJDD_50 | 10967 | 12712 | STR_RS06885 | 0.0 | Capsule | Immune modulation | 98.05 | 100.00 | WP_011227426 |
| ECNIGJDD_4 | 292 | 1707 | STER_RS05250 | 0.0 | Capsule | Immune modulation | 97.88 | 100.00 | WP_011681165 |
| ECNIGJDD_83 | 2081 | 2821 | STER_RS05305 | 0.0 | Capsule | Immune modulation | 97.44 | 99.87 | WP_011681174 |
| ECNIGJDD_83 | 4264 | 5724 | STER_RS05320 | 0.0 | Capsule | Immune modulation | 97.33 | 100.00 | WP_011681177 |
| ECNIGJDD_114 | 9016 | 9974 | cbpD | 0.0 | Autolysin | Exoenzyme | 97.32 | 99.79 | WP_082302295 |
| ECNIGJDD_83 | 2081 | 2821 | STU_RS14635 | 0.0 | Capsule | Immune modulation | 97.03 | 99.87 | WP_011226046 |
| ECNIGJDD_83 | 2831 | 3523 | STU_RS14640 | 0.0 | Capsule | Immune modulation | 96.83 | 99.86 | WP_011226047 |
| ECNIGJDD_83 | 2086 | 2821 | STR_RS05250 | 0.0 | Capsule | Immune modulation | 96.74 | 98.00 | WP_011227246 |
| ECNIGJDD_83 | 2831 | 3523 | STR_RS05255 | 0.0 | Capsule | Immune modulation | 96.54 | 100.00 | WP_011227247 |
| ECNIGJDD_83 | 4264 | 5724 | STU_RS14650 | 0.0 | Capsule | Immune modulation | 96.03 | 100.21 | WP_011226049 |
| ECNIGJDD_83 | 4264 | 5724 | STR_RS05265 | 0.0 | Capsule | Immune modulation | 95.55 | 100.21 | WP_041827043 |
| ECNIGJDD_83 | 659 | 2024 | STER_RS05300 | 0.0 | Capsule | Immune modulation | 95.46 | 99.85 | WP_011681173 |
| ECNIGJDD_83 | 657 | 2024 | STU_RS14630 | 0.0 | Capsule | Immune modulation | 94.08 | 100.00 | WP_011226045 |
| ECNIGJDD_83 | 2831 | 3523 | STER_RS05310 | 0.0 | Capsule | Immune modulation | 89.90 | 100.00 | WP_011681175 |
| ECNIGJDD_105 | 25563 | 26866 | eno | 0.0 | Streptococcal enolase | Exoenzyme | 88.17 | 99.54 | WP_000022832 |
| ECNIGJDD_124 | 295 | 1305 | plr/gapA | 0.0 | Streptococcal plasmin receptor/GAPDH | Adherence | 86.66 | 99.90 | WP_002986042 |
| ECNIGJDD_50 | 14097 | 15320 | SGO_RS05025 | 0.0 | Capsule | Immune modulation | 84.92 | 99.92 | WP_012000441 |
| ECNIGJDD_50 | 15320 | 16126 | SGO_RS05020 | 0.0 | Capsule | Immune modulation | 83.27 | 100.00 | WP_012000440 |
| ECNIGJDD_13 | 2252 | 3535 | tig/ropA | 0.0 | Trigger factor | Stress survival | 80.73 | 99.77 | WP_000107753 |
| ECNIGJDD_48 | 7521 | 8567 | rfbB | 0.0 | Capsule | Immune modulation | 80.61 | 100.00 | WP_009659423 |
| ECNIGJDD_50 | 14583 | 15320 | STR_RS06895 | 0.0 | Capsule | Immune modulation | 96.61 | 61.35 | WP_011227428 |
| ECNIGJDD_50 | 14583 | 15320 | STER_RS07055 | 0.0 | Capsule | Immune modulation | 96.34 | 61.35 | WP_011681436 |
BLASTN v2.16.0 (Database: VFDB, Dec. 2024 release)
VirulenceFinder
| Query ID | Begin | End | Database | Virulence factor | Protein function | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
VirulenceFinder v2.0. 4 (Database: virulencefinder_db, Feb . 2024 release)
Pathogenic genes
PHI-base
| Query ID | qstart | qend | Gene name | e-value | Function | Identity | Coverage | Gene ID |
|---|---|---|---|---|---|---|---|---|
| ECNIGJDD_48 | 47804 | 48787 | ldh(Sp_1220) | 0.0 | L-lactate dehydrogenase | 94.51 | 100.00 | AAK75326 |
| ECNIGJDD_127 | 14016 | 12943 | MntE | 0.0 | manganese homeostasis | 94.41 | 99.72 | ABF32167 |
| ECNIGJDD_22 | 66882 | 69185 | pfl2(Sp_0459) | 0.0 | formate acetyltransferase | 93.10 | 99.22 | AAK74619 |
| ECNIGJDD_105 | 110549 | 109581 | spr0084 | 0.0 | pathogenitcity related | 92.26 | 98.48 | AAK98888 |
| ECNIGJDD_52 | 13139 | 11658 | SPD_0310 | 0.0 | UPF0371 protein SPD_0310 | 92.11 | 100.00 | ABJ54480 |
| ECNIGJDD_47 | 7257 | 9503 | metE | 0.0 | methionine biosynthesis enzymes | 91.99 | 100.00 | AAK74738 |
| ECNIGJDD_53 | 22011 | 23009 | recA | 0.0 | DNA recombination and repair | 91.29 | 85.82 | AAL00560 |
| ECNIGJDD_108 | 15409 | 14438 | prsA2 | 0.0 | ribose-phosphate pyrophosphokinase | 90.12 | 100.00 | ABF36968 |
| ECNIGJDD_50 | 73750 | 72599 | potA | 0.0 | ABC transporter ATP-binding protein-spermidine/putrescine transport | 89.32 | 99.74 | AAL00050 |
| ECNIGJDD_50 | 37532 | 35544 | uvrB | 0.0 | excinuclease ABC, B subunit | 88.84 | 100.00 | AE014259_2 |
| ECNIGJDD_48 | 31606 | 29876 | ptsI | 0.0 | phosphoenolpyruvate-protein phosphotransferase | 88.22 | 100.00 | AAK34199 |
| ECNIGJDD_59 | 6998 | 8476 | IMPDH | 0.0 | inosine-5'-monophosphate dehydrogenase | 87.63 | 100.00 | ADE32434 |
| ECNIGJDD_105 | 26866 | 25565 | Eno | 0.0 | enolase | 86.21 | 99.77 | ABP90468 |
| ECNIGJDD_59 | 21733 | 23625 | gidA | 0.0 | tRNA uridine 5-carboxymethylaminomethyl modification enzyme | 85.74 | 98.90 | ABP91129 |
| ECNIGJDD_47 | 12428 | 10719 | PGM | 0.0 | phosphoglucomutase | 83.89 | 99.65 | ACH87041 |
| ECNIGJDD_121 | 19144 | 20154 | pdh | 0.0 | pyruvate dehydrogenase | 82.79 | 99.70 | ABP91006 |
| ECNIGJDD_44 | 30292 | 31653 | mnmE | 0.0 | central tRNA-modifying GTPase | 82.24 | 99.56 | ABP90420 |
| ECNIGJDD_121 | 69459 | 67567 | PepO | 0.0 | endopeptidase | 80.03 | 100.00 | ABF32980 |
| ECNIGJDD_105 | 41305 | 40415 | bglB | 8.41e-180 | putative phospho--glucosidase | 88.89 | 99.66 | AAK33487 |
| ECNIGJDD_54 | 11807 | 10872 | SP_0676 | 2.02e-169 | transcription facot | 81.73 | 96.89 | AAK74821 |
| ECNIGJDD_47 | 9695 | 10552 | metF | 2.84e-166 | methionine biosynthesis enzymes | 86.36 | 99.31 | AAK74739 |
| ECNIGJDD_113 | 18575 | 19279 | covR | 5.38e-132 | responder protein | 85.11 | 100.00 | AAK71319 |
| ECNIGJDD_52 | 32113 | 32784 | rr01 | 9.58e-126 | response regulator | 83.93 | 99.56 | CAB54566 |
| ECNIGJDD_113 | 18575 | 19279 | walR | 3.21e-122 | DNA-binding response regulator | 81.28 | 100.00 | ANC99504 |
| ECNIGJDD_47 | 16382 | 17050 | CiaR | 3.26e-122 | two-component response regulator | 85.65 | 99.55 | AAK74935 |
| ECNIGJDD_47 | 16382 | 17053 | ciaR | 3.89e-120 | two component system response regulator | 83.48 | 99.12 | AIK75708 |
| ECNIGJDD_122 | 7719 | 7033 | CovR | 3.91e-120 | serves to repress GAS virulence factor-encoding genes | 81.22 | 100.00 | ACE75886 |
| ECNIGJDD_53 | 23285 | 23659 | SpxA2 | 1.48e-71 | transcriptional regulator | 91.20 | 94.70 | ERL21461 |
| ECNIGJDD_120 | 25464 | 25177 | spr0479 | 2.99e-49 | essential gene | 86.46 | 98.97 | AAK99283 |
| ECNIGJDD_51 | 30349 | 30603 | spr1327 | 5.99e-46 | essential gene | 95.29 | 100.00 | AAL00131 |
| ECNIGJDD_57 | 31391 | 31654 | spr0175 | 1.97e-42 | pathogenitcity related | 84.09 | 100.00 | AAK98979 |
| ECNIGJDD_57 | 32194 | 32484 | spr0177 | 1.43e-37 | essential gene | 81.00 | 98.02 | AAK98981 |
| ECNIGJDD_13 | 3693 | 4193 | RopE (M5005_Spy_1611) | 2.28e-77 | probable DNA-directed RNA polymerase subunit delta | 81.44 | 87.43 | AAK34603 |
| ECNIGJDD_22 | 66882 | 69179 | PFL (B9H01_RS01125) | 0.0 | formate C-acetyltransferase | 83.07 | 98.08 | MYN69560 |
| ECNIGJDD_121 | 55006 | 53987 | ilvC (SPD_0406) | 0.0 | ketol-acid reductoisomerase (NADP(+)) | 96.47 | 100.00 | ABJ55451 |
BLASTX v2.16.0 (Database: PHI base v4.16, May. 2024 release)
Plasmid
PlasmidFinder
| Query ID | Begin | End | Plasmid | Query / Template | Identity | Accession no. |
|---|---|---|---|---|---|---|
| No hit found | ||||||
PlasmidFinder v 2.1.6 (Database: plasmidfinder_db v 2.2.0 , Nov. 2024 release)
PlasmidHunter
| Query ID | Prediction | Chromosome | Plasmid |
|---|---|---|---|
| ECNIGJDD_1 | 0.0 | 1.0 | 0.0 |
| ECNIGJDD_2 | 0.0 | 1.0 | 0.0 |
| ECNIGJDD_3 | 1.0 | 0.0 | 1.0 |
| ECNIGJDD_4 | 0.0 | 1.0 | 0.0 |
| ECNIGJDD_6 | 0.0 | 1.0 | 0.0 |
| ECNIGJDD_11 | 0.0 | 1.0 | 0.0 |
| ECNIGJDD_13 | 0.0 | 1.0 | 0.0 |
| ECNIGJDD_14 | 1.0 | 0.0 | 1.0 |
| ECNIGJDD_15 | 1.0 | 0.0 | 1.0 |
| ECNIGJDD_18 | 0.0 | 1.0 | 0.0 |
| ECNIGJDD_19 | 1.0 | 0.0 | 1.0 |
| ECNIGJDD_22 | 0.0 | 1.0 | 0.0 |
| ECNIGJDD_24 | 1.0 | 0.0 | 1.0 |
| ECNIGJDD_25 | 0.0 | 1.0 | 0.0 |
| ECNIGJDD_27 | 0.0 | 1.0 | 0.0 |
| ECNIGJDD_34 | 1.0 | 0.0 | 1.0 |
| ECNIGJDD_41 | 0.0 | 1.0 | 0.0 |
| ECNIGJDD_44 | 0.0 | 1.0 | 0.0 |
| ECNIGJDD_45 | 0.0 | 1.0 | 0.0 |
| ECNIGJDD_46 | 0.0 | 1.0 | 0.0 |
| ECNIGJDD_47 | 0.0 | 1.0 | 0.0 |
| ECNIGJDD_48 | 0.0 | 1.0 | 0.0 |
| ECNIGJDD_49 | 0.0 | 1.0 | 0.0 |
| ECNIGJDD_50 | 0.0 | 1.0 | 0.0 |
| ECNIGJDD_51 | 0.0 | 1.0 | 0.0 |
| ECNIGJDD_52 | 0.0 | 1.0 | 0.0 |
| ECNIGJDD_53 | 0.0 | 1.0 | 0.0 |
| ECNIGJDD_54 | 0.0 | 1.0 | 0.0 |
| ECNIGJDD_55 | 0.0 | 1.0 | 0.0 |
| ECNIGJDD_56 | 0.0 | 1.0 | 0.0 |
| ECNIGJDD_57 | 0.0 | 1.0 | 0.0 |
| ECNIGJDD_58 | 1.0 | 0.0 | 1.0 |
| ECNIGJDD_59 | 0.0 | 1.0 | 0.0 |
| ECNIGJDD_60 | 0.0 | 1.0 | 0.0 |
| ECNIGJDD_61 | 0.0 | 1.0 | 0.0 |
| ECNIGJDD_65 | 0.0 | 1.0 | 0.0 |
| ECNIGJDD_66 | 0.0 | 1.0 | 0.0 |
| ECNIGJDD_67 | 0.0 | 1.0 | 0.0 |
| ECNIGJDD_68 | 0.0 | 1.0 | 0.0 |
| ECNIGJDD_69 | 1.0 | 0.0 | 1.0 |
| ECNIGJDD_70 | 0.0 | 1.0 | 0.0 |
| ECNIGJDD_72 | 0.0 | 1.0 | 0.0 |
| ECNIGJDD_73 | 0.0 | 1.0 | 0.0 |
| ECNIGJDD_74 | 0.0 | 1.0 | 0.0 |
| ECNIGJDD_78 | 0.0 | 1.0 | 0.0 |
| ECNIGJDD_80 | 0.0 | 1.0 | 0.0 |
| ECNIGJDD_81 | 1.0 | 0.0 | 1.0 |
| ECNIGJDD_83 | 0.0 | 1.0 | 0.0 |
| ECNIGJDD_90 | 0.0 | 1.0 | 0.0 |
| ECNIGJDD_104 | 0.0 | 1.0 | 0.0 |
| ECNIGJDD_105 | 0.0 | 1.0 | 0.0 |
| ECNIGJDD_107 | 0.0 | 1.0 | 0.0 |
| ECNIGJDD_108 | 0.0 | 1.0 | 0.0 |
| ECNIGJDD_109 | 0.0 | 1.0 | 0.0 |
| ECNIGJDD_110 | 0.0 | 1.0 | 0.0 |
| ECNIGJDD_111 | 0.0 | 1.0 | 0.0 |
| ECNIGJDD_112 | 0.0 | 1.0 | 0.0 |
| ECNIGJDD_113 | 0.0 | 1.0 | 0.0 |
| ECNIGJDD_114 | 0.0 | 1.0 | 0.0 |
| ECNIGJDD_115 | 1.0 | 0.0 | 1.0 |
| ECNIGJDD_116 | 0.0 | 1.0 | 0.0 |
| ECNIGJDD_117 | 0.0 | 1.0 | 0.0 |
| ECNIGJDD_118 | 0.0 | 1.0 | 0.0 |
| ECNIGJDD_119 | 0.0 | 1.0 | 0.0 |
| ECNIGJDD_120 | 0.0 | 1.0 | 0.0 |
| ECNIGJDD_121 | 0.0 | 1.0 | 0.0 |
| ECNIGJDD_122 | 0.0 | 1.0 | 0.0 |
| ECNIGJDD_123 | 0.0 | 1.0 | 0.0 |
| ECNIGJDD_124 | 0.0 | 1.0 | 0.0 |
| ECNIGJDD_125 | 0.0 | 1.0 | 0.0 |
| ECNIGJDD_126 | 0.0 | 1.0 | 0.0 |
| ECNIGJDD_127 | 0.0 | 1.0 | 0.0 |
| ECNIGJDD_128 | 0.0 | 1.0 | 0.0 |
| ECNIGJDD_129 | 0.0 | 1.0 | 0.0 |
| ECNIGJDD_130 | 0.0 | 1.0 | 0.0 |
| ECNIGJDD_131 | 0.0 | 1.0 | 0.0 |
PlasmidHunter v 1.4.5 (Database: May. 2024 release)
Prophage
Phigaro
| Query ID | Begin | End | Transposable | Taxonomy | pVOGs |
|---|---|---|---|---|---|
| No hit found | |||||
Phigaro v2.4.0 (Database: Jan. 2024 release)