Probiotic potential risk score
| ARGs | VFs | PGs | PPRS |
|---|---|---|---|
| 0 | 21 | 32 | 38.28 |
PPRS is classified as low-risk (≤4), medium-risk (4-6), and high-risk (≥6).
Antibiotic resistance genes
Comprehensive Antibiotic Resistance Database (CARD)
| Query ID | Begin | End | ARO name | ARO accession | CARD name | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
RGI v6.0.3 (Database: CARD Variants v4.0.2, Nov. 2023 release)
ResFinder
| Query ID | Begin | End | Resistance gene | Phenotype | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|
| No hit found | |||||||
ResFinder v4.6.0 (Database: resfinder_db, Aug. 2024 release)
AMRFinderPlus
| Query ID | Begin | End | Gene symbol | Sequence name | Method | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
AMRFinderPlus v4.0.3 (Database: Oct. 2024 release)
Virulence factors
Virulence Factor Database (VFDB)
| Query ID | qstart | qend | Gene name | e-value | VF name | VF category | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|---|
| ODCGICLO_28 | 50870 | 51838 | cbpD | 0.0 | Autolysin | Exoenzyme | 100.00 | 100.00 | WP_082302295 |
| ODCGICLO_63 | 52125 | 52915 | cshA | 0.0 | Cell surface hydrophobicity proteins | Adherence | 100.00 | 100.00 | - |
| ODCGICLO_62 | 19728 | 20579 | rfbD | 0.0 | Capsule | Immune modulation | 100.00 | 100.00 | WP_014621820 |
| ODCGICLO_63 | 96944 | 97537 | STU_RS15260 | 0.0 | Capsule | Immune modulation | 100.00 | 100.00 | WP_011226149 |
| ODCGICLO_62 | 9277 | 11061 | STU_RS16230 | 0.0 | Capsule | Immune modulation | 100.00 | 100.00 | WP_011226325 |
| ODCGICLO_62 | 11058 | 12113 | STU_RS16235 | 0.0 | Capsule | Immune modulation | 100.00 | 100.00 | WP_002948022 |
| ODCGICLO_62 | 12133 | 13338 | STU_RS16240 | 0.0 | Capsule | Immune modulation | 100.00 | 100.00 | WP_011226326 |
| ODCGICLO_62 | 13338 | 14147 | STU_RS16245 | 0.0 | Capsule | Immune modulation | 100.00 | 100.00 | WP_002948020 |
| ODCGICLO_62 | 14131 | 15087 | STU_RS16250 | 0.0 | Capsule | Immune modulation | 100.00 | 100.00 | WP_011226328 |
| ODCGICLO_62 | 16341 | 17351 | STU_RS16260 | 0.0 | Capsule | Immune modulation | 100.00 | 100.00 | WP_011226330 |
| ODCGICLO_62 | 17351 | 18625 | STU_RS16265 | 0.0 | Capsule | Immune modulation | 100.00 | 100.00 | WP_011226331 |
| ODCGICLO_62 | 15084 | 16232 | STU_RS16255 | 0.0 | Capsule | Immune modulation | 99.91 | 100.00 | WP_041828290 |
| ODCGICLO_63 | 132303 | 133064 | srtA | 0.0 | Sortase A | Exoenzyme | 99.87 | 100.00 | - |
| ODCGICLO_11 | 6528 | 7982 | STR_RS05265 | 0.0 | Capsule | Immune modulation | 99.86 | 100.00 | WP_041827043 |
| ODCGICLO_63 | 96944 | 97537 | STR_RS05880 | 0.0 | Capsule | Immune modulation | 99.83 | 100.00 | WP_011226149 |
| ODCGICLO_63 | 96944 | 97537 | STER_RS06030 | 0.0 | Capsule | Immune modulation | 99.66 | 100.00 | WP_011226149 |
| ODCGICLO_21 | 5371 | 7029 | fbp54 | 0.0 | FBPs | Adherence | 99.58 | 100.00 | WP_011227179 |
| ODCGICLO_63 | 97537 | 98406 | rfbA | 0.0 | Capsule | Immune modulation | 99.54 | 100.00 | WP_011681286 |
| ODCGICLO_11 | 6528 | 7982 | STU_RS14650 | 0.0 | Capsule | Immune modulation | 97.94 | 100.00 | WP_011226049 |
| ODCGICLO_11 | 6528 | 7982 | STER_RS05320 | 0.0 | Capsule | Immune modulation | 96.92 | 99.79 | WP_011681177 |
| ODCGICLO_26 | 28065 | 29368 | eno | 0.0 | Streptococcal enolase | Exoenzyme | 88.09 | 99.54 | WP_000022832 |
| ODCGICLO_83 | 226 | 1236 | plr/gapA | 0.0 | Streptococcal plasmin receptor/GAPDH | Adherence | 86.92 | 99.51 | WP_002986042 |
| ODCGICLO_63 | 95468 | 96514 | rfbB | 0.0 | Capsule | Immune modulation | 80.71 | 100.00 | WP_009659423 |
| ODCGICLO_37 | 2308 | 3591 | tig/ropA | 0.0 | Trigger factor | Stress survival | 80.50 | 99.77 | WP_000107753 |
| ODCGICLO_11 | 2557 | 3140 | SPD_RS01775 | 1.18e-148 | Capsule | Immune modulation | 83.08 | 96.20 | WP_001819836 |
| ODCGICLO_11 | 6063 | 6527 | STR_RS05260 | 0.0 | Capsule | Immune modulation | 99.78 | 63.52 | WP_011227248 |
| ODCGICLO_11 | 6063 | 6527 | STU_RS14645 | 0.0 | Capsule | Immune modulation | 98.28 | 63.52 | WP_011226048 |
| ODCGICLO_11 | 6063 | 6527 | STER_RS05315 | 0.0 | Capsule | Immune modulation | 97.20 | 63.52 | WP_011681176 |
BLASTN v2.16.0 (Database: VFDB, Dec. 2024 release)
VirulenceFinder
| Query ID | Begin | End | Database | Virulence factor | Protein function | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
VirulenceFinder v2.0. 4 (Database: virulencefinder_db, Feb . 2024 release)
Pathogenic genes
PHI-base
| Query ID | qstart | qend | Gene name | e-value | Function | Identity | Coverage | Gene ID |
|---|---|---|---|---|---|---|---|---|
| ODCGICLO_63 | 135751 | 136734 | ldh(Sp_1220) | 0.0 | L-lactate dehydrogenase | 94.82 | 100.00 | AAK75326 |
| ODCGICLO_89 | 24358 | 25431 | MntE | 0.0 | manganese homeostasis | 94.41 | 99.72 | ABF32167 |
| ODCGICLO_26 | 111605 | 110637 | spr0084 | 0.0 | pathogenitcity related | 93.19 | 98.48 | AAK98888 |
| ODCGICLO_62 | 183771 | 186074 | pfl2(Sp_0459) | 0.0 | formate acetyltransferase | 92.97 | 99.22 | AAK74619 |
| ODCGICLO_24 | 19479 | 20960 | SPD_0310 | 0.0 | UPF0371 protein SPD_0310 | 91.90 | 100.00 | ABJ54480 |
| ODCGICLO_74 | 13900 | 16146 | metE | 0.0 | methionine biosynthesis enzymes | 91.86 | 100.00 | AAK74738 |
| ODCGICLO_72 | 1974 | 982 | recA | 0.0 | DNA recombination and repair | 91.24 | 85.31 | AAL00560 |
| ODCGICLO_23 | 15471 | 14500 | prsA2 | 0.0 | ribose-phosphate pyrophosphokinase | 90.12 | 100.00 | ABF36968 |
| ODCGICLO_62 | 70034 | 68883 | potA | 0.0 | ABC transporter ATP-binding protein-spermidine/putrescine transport | 89.06 | 99.74 | AAL00050 |
| ODCGICLO_62 | 35561 | 33579 | uvrB | 0.0 | excinuclease ABC, B subunit | 88.96 | 99.70 | AE014259_2 |
| ODCGICLO_63 | 119557 | 117827 | ptsI | 0.0 | phosphoenolpyruvate-protein phosphotransferase | 87.87 | 100.00 | AAK34199 |
| ODCGICLO_66 | 29825 | 28347 | IMPDH | 0.0 | inosine-5'-monophosphate dehydrogenase | 87.22 | 100.00 | ADE32434 |
| ODCGICLO_26 | 29368 | 28067 | Eno | 0.0 | enolase | 86.21 | 99.77 | ABP90468 |
| ODCGICLO_66 | 15089 | 13197 | gidA | 0.0 | tRNA uridine 5-carboxymethylaminomethyl modification enzyme | 85.89 | 98.90 | ABP91129 |
| ODCGICLO_74 | 19071 | 17362 | PGM | 0.0 | phosphoglucomutase | 83.89 | 99.65 | ACH87041 |
| ODCGICLO_8 | 18849 | 19859 | pdh | 0.0 | pyruvate dehydrogenase | 83.09 | 99.70 | ABP91006 |
| ODCGICLO_64 | 44712 | 46073 | mnmE | 0.0 | central tRNA-modifying GTPase | 82.02 | 99.56 | ABP90420 |
| ODCGICLO_10 | 48451 | 46559 | PepO | 0.0 | endopeptidase | 80.03 | 100.00 | ABF32980 |
| ODCGICLO_26 | 43798 | 42908 | bglB | 9.76e-180 | putative phospho--glucosidase | 88.89 | 99.66 | AAK33487 |
| ODCGICLO_17 | 13405 | 12470 | SP_0676 | 2.38e-169 | transcription facot | 81.73 | 96.89 | AAK74821 |
| ODCGICLO_74 | 16338 | 17195 | metF | 1.15e-166 | methionine biosynthesis enzymes | 86.36 | 99.31 | AAK74739 |
| ODCGICLO_63 | 24446 | 23742 | covR | 2.99e-131 | responder protein | 84.68 | 100.00 | AAK71319 |
| ODCGICLO_43 | 29873 | 29202 | rr01 | 2.35e-127 | response regulator | 84.38 | 99.56 | CAB54566 |
| ODCGICLO_63 | 24446 | 23742 | walR | 2.15e-121 | DNA-binding response regulator | 80.85 | 100.00 | ANC99504 |
| ODCGICLO_68 | 10057 | 9371 | CovR | 1.70e-119 | serves to repress GAS virulence factor-encoding genes | 80.79 | 100.00 | ACE75886 |
| ODCGICLO_74 | 23025 | 23693 | CiaR | 9.52e-119 | two-component response regulator | 83.86 | 99.55 | AAK74935 |
| ODCGICLO_74 | 23025 | 23696 | ciaR | 9.46e-117 | two component system response regulator | 81.70 | 99.12 | AIK75708 |
| ODCGICLO_72 | 685 | 290 | SpxA2 | 2.79e-76 | transcriptional regulator | 90.91 | 100.00 | ERL21461 |
| ODCGICLO_30 | 13397 | 13684 | spr0479 | 3.37e-49 | essential gene | 86.46 | 98.97 | AAK99283 |
| ODCGICLO_28 | 9907 | 9653 | spr1327 | 1.05e-45 | essential gene | 95.29 | 100.00 | AAL00131 |
| ODCGICLO_60 | 14622 | 14885 | spr0175 | 1.59e-42 | pathogenitcity related | 84.09 | 100.00 | AAK98979 |
| ODCGICLO_60 | 15449 | 15715 | spr0177 | 4.10e-34 | essential gene | 84.27 | 88.12 | AAK98981 |
| ODCGICLO_37 | 3749 | 4249 | RopE (M5005_Spy_1611) | 3.54e-76 | probable DNA-directed RNA polymerase subunit delta | 80.84 | 87.43 | AAK34603 |
| ODCGICLO_62 | 183771 | 186068 | PFL (B9H01_RS01125) | 0.0 | formate C-acetyltransferase | 82.94 | 98.08 | MYN69560 |
| ODCGICLO_10 | 33990 | 32971 | ilvC (SPD_0406) | 0.0 | ketol-acid reductoisomerase (NADP(+)) | 96.18 | 100.00 | ABJ55451 |
BLASTX v2.16.0 (Database: PHI base v4.16, May. 2024 release)
Plasmid
PlasmidFinder
| Query ID | Begin | End | Plasmid | Query / Template | Identity | Accession no. |
|---|---|---|---|---|---|---|
| No hit found | ||||||
PlasmidFinder v 2.1.6 (Database: plasmidfinder_db v 2.2.0 , Nov. 2024 release)
PlasmidHunter
| Query ID | Prediction | Chromosome | Plasmid |
|---|---|---|---|
| ODCGICLO_3 | 0.0 | 1.0 | 0.0 |
| ODCGICLO_4 | 0.0 | 1.0 | 0.0 |
| ODCGICLO_7 | 0.0 | 1.0 | 0.0 |
| ODCGICLO_8 | 0.0 | 1.0 | 0.0 |
| ODCGICLO_9 | 1.0 | 0.0 | 1.0 |
| ODCGICLO_10 | 0.0 | 1.0 | 0.0 |
| ODCGICLO_11 | 0.0 | 1.0 | 0.0 |
| ODCGICLO_12 | 0.0 | 1.0 | 0.0 |
| ODCGICLO_13 | 0.0 | 1.0 | 0.0 |
| ODCGICLO_14 | 0.0 | 1.0 | 0.0 |
| ODCGICLO_15 | 0.0 | 1.0 | 0.0 |
| ODCGICLO_17 | 0.0 | 1.0 | 0.0 |
| ODCGICLO_18 | 0.0 | 1.0 | 0.0 |
| ODCGICLO_19 | 0.0 | 1.0 | 0.0 |
| ODCGICLO_20 | 0.0 | 1.0 | 0.0 |
| ODCGICLO_21 | 0.0 | 1.0 | 0.0 |
| ODCGICLO_22 | 0.0 | 1.0 | 0.0 |
| ODCGICLO_23 | 0.0 | 1.0 | 0.0 |
| ODCGICLO_24 | 0.0 | 1.0 | 0.0 |
| ODCGICLO_25 | 0.0 | 1.0 | 0.0 |
| ODCGICLO_26 | 0.0 | 1.0 | 0.0 |
| ODCGICLO_27 | 0.0 | 1.0 | 0.0 |
| ODCGICLO_28 | 0.0 | 1.0 | 0.0 |
| ODCGICLO_29 | 0.0 | 1.0 | 0.0 |
| ODCGICLO_30 | 0.0 | 1.0 | 0.0 |
| ODCGICLO_33 | 0.0 | 1.0 | 0.0 |
| ODCGICLO_37 | 0.0 | 1.0 | 0.0 |
| ODCGICLO_40 | 0.0 | 1.0 | 0.0 |
| ODCGICLO_43 | 0.0 | 1.0 | 0.0 |
| ODCGICLO_46 | 0.0 | 1.0 | 0.0 |
| ODCGICLO_50 | 0.0 | 1.0 | 0.0 |
| ODCGICLO_51 | 0.0 | 1.0 | 0.0 |
| ODCGICLO_55 | 1.0 | 0.0 | 1.0 |
| ODCGICLO_60 | 0.0 | 1.0 | 0.0 |
| ODCGICLO_61 | 0.0 | 1.0 | 0.0 |
| ODCGICLO_62 | 0.0 | 1.0 | 0.0 |
| ODCGICLO_63 | 0.0 | 1.0 | 0.0 |
| ODCGICLO_64 | 0.0 | 1.0 | 0.0 |
| ODCGICLO_65 | 0.0 | 1.0 | 0.0 |
| ODCGICLO_66 | 0.0 | 1.0 | 0.0 |
| ODCGICLO_67 | 0.0 | 1.0 | 0.0 |
| ODCGICLO_68 | 0.0 | 1.0 | 0.0 |
| ODCGICLO_69 | 0.0 | 1.0 | 0.0 |
| ODCGICLO_70 | 0.0 | 1.0 | 0.0 |
| ODCGICLO_72 | 0.0 | 1.0 | 0.0 |
| ODCGICLO_73 | 0.0 | 1.0 | 0.0 |
| ODCGICLO_74 | 0.0 | 1.0 | 0.0 |
| ODCGICLO_75 | 0.0 | 1.0 | 0.0 |
| ODCGICLO_76 | 1.0 | 0.0 | 1.0 |
| ODCGICLO_77 | 0.0 | 1.0 | 0.0 |
| ODCGICLO_79 | 0.0 | 1.0 | 0.0 |
| ODCGICLO_80 | 0.0 | 1.0 | 0.0 |
| ODCGICLO_83 | 0.0 | 1.0 | 0.0 |
| ODCGICLO_84 | 1.0 | 0.0 | 1.0 |
| ODCGICLO_88 | 0.0 | 1.0 | 0.0 |
| ODCGICLO_89 | 0.0 | 1.0 | 0.0 |
PlasmidHunter v 1.4.5 (Database: May. 2024 release)
Prophage
Phigaro
| Query ID | Begin | End | Transposable | Taxonomy | pVOGs |
|---|---|---|---|---|---|
| No hit found | |||||
Phigaro v2.4.0 (Database: Jan. 2024 release)