Probiotic potential risk score
| ARGs | VFs | PGs | PPRS |
|---|---|---|---|
| 0 | 25 | 33 | 41.40 |
PPRS is classified as low-risk (≤4), medium-risk (4-6), and high-risk (≥6).
Antibiotic resistance genes
Comprehensive Antibiotic Resistance Database (CARD)
| Query ID | Begin | End | ARO name | ARO accession | CARD name | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
RGI v6.0.3 (Database: CARD Variants v4.0.2, Nov. 2023 release)
ResFinder
| Query ID | Begin | End | Resistance gene | Phenotype | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|
| No hit found | |||||||
ResFinder v4.6.0 (Database: resfinder_db, Aug. 2024 release)
AMRFinderPlus
| Query ID | Begin | End | Gene symbol | Sequence name | Method | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
AMRFinderPlus v4.0.3 (Database: Oct. 2024 release)
Virulence factors
Virulence Factor Database (VFDB)
| Query ID | qstart | qend | Gene name | e-value | VF name | VF category | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|---|
| CAPAEKBJ_100 | 9587 | 10456 | rfbA | 0.0 | Capsule | Immune modulation | 100.00 | 100.00 | WP_011681286 |
| CAPAEKBJ_100 | 8994 | 9587 | STER_RS06030 | 0.0 | Capsule | Immune modulation | 100.00 | 100.00 | WP_011226149 |
| CAPAEKBJ_92 | 155506 | 156315 | STU_RS16245 | 0.0 | Capsule | Immune modulation | 99.88 | 100.00 | WP_002948020 |
| CAPAEKBJ_100 | 8994 | 9587 | STR_RS05880 | 0.0 | Capsule | Immune modulation | 99.83 | 100.00 | WP_011226149 |
| CAPAEKBJ_92 | 154566 | 155522 | STU_RS16250 | 0.0 | Capsule | Immune modulation | 99.79 | 100.00 | WP_011226328 |
| CAPAEKBJ_92 | 153421 | 154569 | STU_RS16255 | 0.0 | Capsule | Immune modulation | 99.74 | 100.00 | WP_041828290 |
| CAPAEKBJ_92 | 156315 | 157520 | STU_RS16240 | 0.0 | Capsule | Immune modulation | 99.67 | 100.00 | WP_011226326 |
| CAPAEKBJ_100 | 8994 | 9587 | STU_RS15260 | 0.0 | Capsule | Immune modulation | 99.66 | 100.00 | WP_011226149 |
| CAPAEKBJ_92 | 149074 | 149925 | rfbD | 0.0 | Capsule | Immune modulation | 99.65 | 100.00 | WP_014621820 |
| CAPAEKBJ_101 | 3733 | 5391 | fbp54 | 0.0 | FBPs | Adherence | 99.58 | 100.00 | WP_011227179 |
| CAPAEKBJ_92 | 158592 | 160376 | STU_RS16230 | 0.0 | Capsule | Immune modulation | 99.50 | 100.00 | WP_011226325 |
| CAPAEKBJ_92 | 152302 | 153312 | STU_RS16260 | 0.0 | Capsule | Immune modulation | 99.50 | 100.00 | WP_011226330 |
| CAPAEKBJ_92 | 157540 | 158595 | STU_RS16235 | 0.0 | Capsule | Immune modulation | 99.43 | 100.00 | WP_002948022 |
| CAPAEKBJ_97 | 14617 | 15378 | srtA | 0.0 | Sortase A | Exoenzyme | 99.21 | 100.00 | - |
| CAPAEKBJ_8 | 1571 | 2302 | STER_RS05315 | 0.0 | Capsule | Immune modulation | 99.04 | 100.00 | WP_011681176 |
| CAPAEKBJ_8 | 110 | 1570 | STER_RS05320 | 0.0 | Capsule | Immune modulation | 98.97 | 100.00 | WP_011681177 |
| CAPAEKBJ_112 | 57045 | 58013 | cbpD | 0.0 | Autolysin | Exoenzyme | 98.86 | 100.00 | WP_082302295 |
| CAPAEKBJ_74 | 483 | 1898 | STER_RS05250 | 0.0 | Capsule | Immune modulation | 98.31 | 100.00 | WP_011681165 |
| CAPAEKBJ_8 | 1571 | 2302 | STR_RS05260 | 0.0 | Capsule | Immune modulation | 98.09 | 100.00 | WP_011227248 |
| CAPAEKBJ_93 | 815 | 1610 | cshA | 0.0 | Cell surface hydrophobicity proteins | Adherence | 97.99 | 100.51 | - |
| CAPAEKBJ_8 | 1571 | 2302 | STU_RS14645 | 0.0 | Capsule | Immune modulation | 97.95 | 100.00 | WP_011226048 |
| CAPAEKBJ_92 | 151028 | 152299 | STU_RS16265 | 0.0 | Capsule | Immune modulation | 97.48 | 99.76 | WP_011226331 |
| CAPAEKBJ_8 | 110 | 1570 | STU_RS14650 | 0.0 | Capsule | Immune modulation | 97.26 | 100.21 | WP_011226049 |
| CAPAEKBJ_8 | 3013 | 3754 | STU_RS14635 | 0.0 | Capsule | Immune modulation | 97.17 | 100.00 | WP_011226046 |
| CAPAEKBJ_8 | 3013 | 3754 | STER_RS05305 | 0.0 | Capsule | Immune modulation | 96.77 | 100.00 | WP_011681174 |
| CAPAEKBJ_8 | 110 | 1570 | STR_RS05265 | 0.0 | Capsule | Immune modulation | 96.72 | 100.21 | WP_041827043 |
| CAPAEKBJ_8 | 3013 | 3749 | STR_RS05250 | 0.0 | Capsule | Immune modulation | 96.20 | 98.13 | WP_011227246 |
| CAPAEKBJ_8 | 3811 | 5178 | STU_RS14630 | 0.0 | Capsule | Immune modulation | 95.61 | 100.00 | WP_011226045 |
| CAPAEKBJ_8 | 2311 | 3003 | STR_RS05255 | 0.0 | Capsule | Immune modulation | 95.25 | 99.86 | WP_011227247 |
| CAPAEKBJ_8 | 2311 | 3003 | STU_RS14640 | 0.0 | Capsule | Immune modulation | 95.25 | 99.86 | WP_011226047 |
| CAPAEKBJ_8 | 3811 | 5176 | STER_RS05300 | 0.0 | Capsule | Immune modulation | 94.95 | 99.85 | WP_011681173 |
| CAPAEKBJ_8 | 2311 | 3003 | STER_RS05310 | 0.0 | Capsule | Immune modulation | 89.75 | 100.00 | WP_011681175 |
| CAPAEKBJ_99 | 94367 | 95670 | eno | 0.0 | Streptococcal enolase | Exoenzyme | 88.10 | 99.46 | WP_000022832 |
| CAPAEKBJ_3 | 14299 | 15309 | plr/gapA | 0.0 | Streptococcal plasmin receptor/GAPDH | Adherence | 87.55 | 99.90 | WP_002986042 |
| CAPAEKBJ_40 | 2594 | 3877 | tig/ropA | 0.0 | Trigger factor | Stress survival | 80.73 | 99.77 | WP_000107753 |
| CAPAEKBJ_100 | 7519 | 8565 | rfbB | 0.0 | Capsule | Immune modulation | 80.61 | 100.00 | WP_009659423 |
BLASTN v2.16.0 (Database: VFDB, Dec. 2024 release)
VirulenceFinder
| Query ID | Begin | End | Database | Virulence factor | Protein function | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
VirulenceFinder v2.0. 4 (Database: virulencefinder_db, Feb . 2024 release)
Pathogenic genes
PHI-base
| Query ID | qstart | qend | Gene name | e-value | Function | Identity | Coverage | Gene ID |
|---|---|---|---|---|---|---|---|---|
| CAPAEKBJ_97 | 18065 | 19048 | ldh(Sp_1220) | 0.0 | L-lactate dehydrogenase | 94.82 | 100.00 | AAK75326 |
| CAPAEKBJ_42 | 27671 | 28744 | MntE | 0.0 | manganese homeostasis | 94.13 | 99.72 | ABF32167 |
| CAPAEKBJ_99 | 12085 | 13053 | spr0084 | 0.0 | pathogenitcity related | 93.19 | 98.48 | AAK98888 |
| CAPAEKBJ_35 | 13820 | 11517 | pfl2(Sp_0459) | 0.0 | formate acetyltransferase | 92.97 | 99.22 | AAK74619 |
| CAPAEKBJ_10 | 74038 | 72557 | SPD_0310 | 0.0 | UPF0371 protein SPD_0310 | 92.31 | 100.00 | ABJ54480 |
| CAPAEKBJ_34 | 11359 | 9113 | metE | 0.0 | methionine biosynthesis enzymes | 91.86 | 100.00 | AAK74738 |
| CAPAEKBJ_84 | 20276 | 21268 | recA | 0.0 | DNA recombination and repair | 91.24 | 85.31 | AAL00560 |
| CAPAEKBJ_49 | 15407 | 14436 | prsA2 | 0.0 | ribose-phosphate pyrophosphokinase | 89.81 | 100.00 | ABF36968 |
| CAPAEKBJ_92 | 98349 | 99500 | potA | 0.0 | ABC transporter ATP-binding protein-spermidine/putrescine transport | 89.32 | 99.74 | AAL00050 |
| CAPAEKBJ_92 | 134104 | 136092 | uvrB | 0.0 | excinuclease ABC, B subunit | 88.84 | 100.00 | AE014259_2 |
| CAPAEKBJ_97 | 1868 | 138 | ptsI | 0.0 | phosphoenolpyruvate-protein phosphotransferase | 88.04 | 100.00 | AAK34199 |
| CAPAEKBJ_105 | 10692 | 9214 | IMPDH | 0.0 | inosine-5'-monophosphate dehydrogenase | 87.42 | 100.00 | ADE32434 |
| CAPAEKBJ_99 | 94367 | 95668 | Eno | 0.0 | enolase | 86.21 | 99.77 | ABP90468 |
| CAPAEKBJ_104 | 65034 | 63142 | gidA | 0.0 | tRNA uridine 5-carboxymethylaminomethyl modification enzyme | 86.05 | 98.90 | ABP91129 |
| CAPAEKBJ_34 | 6188 | 7897 | PGM | 0.0 | phosphoglucomutase | 84.06 | 99.65 | ACH87041 |
| CAPAEKBJ_98 | 18832 | 19842 | pdh | 0.0 | pyruvate dehydrogenase | 82.49 | 99.70 | ABP91006 |
| CAPAEKBJ_50 | 30230 | 31591 | mnmE | 0.0 | central tRNA-modifying GTPase | 82.24 | 99.56 | ABP90420 |
| CAPAEKBJ_86 | 4721 | 6613 | PepO | 0.0 | endopeptidase | 80.19 | 100.00 | ABF32980 |
| CAPAEKBJ_99 | 79931 | 80821 | bglB | 3.11e-179 | putative phospho--glucosidase | 88.55 | 99.66 | AAK33487 |
| CAPAEKBJ_51 | 11808 | 10873 | SP_0676 | 2.08e-169 | transcription facot | 81.73 | 96.89 | AAK74821 |
| CAPAEKBJ_34 | 8921 | 8064 | metF | 1.35e-166 | methionine biosynthesis enzymes | 86.36 | 99.31 | AAK74739 |
| CAPAEKBJ_93 | 31650 | 32354 | covR | 1.32e-132 | responder protein | 85.53 | 100.00 | AAK71319 |
| CAPAEKBJ_10 | 93015 | 93686 | rr01 | 1.63e-125 | response regulator | 83.93 | 99.56 | CAB54566 |
| CAPAEKBJ_93 | 31650 | 32354 | walR | 5.54e-123 | DNA-binding response regulator | 82.13 | 100.00 | ANC99504 |
| CAPAEKBJ_95 | 7709 | 7023 | CovR | 1.30e-119 | serves to repress GAS virulence factor-encoding genes | 80.79 | 100.00 | ACE75886 |
| CAPAEKBJ_34 | 2234 | 1566 | CiaR | 1.80e-119 | two-component response regulator | 84.31 | 99.55 | AAK74935 |
| CAPAEKBJ_34 | 2234 | 1563 | ciaR | 1.77e-117 | two component system response regulator | 82.14 | 99.12 | AIK75708 |
| CAPAEKBJ_84 | 21565 | 21960 | SpxA2 | 4.39e-75 | transcriptional regulator | 90.15 | 100.00 | ERL21461 |
| CAPAEKBJ_50 | 18880 | 18479 | SpxA1 | 6.40e-68 | transcriptional regulator | 80.60 | 100.00 | ERL19273 |
| CAPAEKBJ_94 | 22766 | 22479 | spr0479 | 2.78e-49 | essential gene | 86.46 | 98.97 | AAK99283 |
| CAPAEKBJ_112 | 98905 | 99159 | spr1327 | 1.13e-44 | essential gene | 94.12 | 100.00 | AAL00131 |
| CAPAEKBJ_104 | 31392 | 31655 | spr0175 | 2.68e-42 | pathogenitcity related | 84.09 | 100.00 | AAK98979 |
| CAPAEKBJ_104 | 32219 | 32485 | spr0177 | 5.87e-34 | essential gene | 84.27 | 88.12 | AAK98981 |
| CAPAEKBJ_40 | 4035 | 4535 | RopE (M5005_Spy_1611) | 1.67e-76 | probable DNA-directed RNA polymerase subunit delta | 81.44 | 87.43 | AAK34603 |
| CAPAEKBJ_35 | 13820 | 11523 | PFL (B9H01_RS01125) | 0.0 | formate C-acetyltransferase | 82.94 | 98.08 | MYN69560 |
| CAPAEKBJ_86 | 19193 | 20212 | ilvC (SPD_0406) | 0.0 | ketol-acid reductoisomerase (NADP(+)) | 96.47 | 100.00 | ABJ55451 |
BLASTX v2.16.0 (Database: PHI base v4.16, May. 2024 release)
Plasmid
PlasmidFinder
| Query ID | Begin | End | Plasmid | Query / Template | Identity | Accession no. |
|---|---|---|---|---|---|---|
| No hit found | ||||||
PlasmidFinder v 2.1.6 (Database: plasmidfinder_db v 2.2.0 , Nov. 2024 release)
PlasmidHunter
| Query ID | Prediction | Chromosome | Plasmid |
|---|---|---|---|
| CAPAEKBJ_2 | 0.0 | 1.0 | 0.0 |
| CAPAEKBJ_3 | 0.0 | 1.0 | 0.0 |
| CAPAEKBJ_4 | 0.0 | 1.0 | 0.0 |
| CAPAEKBJ_5 | 0.0 | 1.0 | 0.0 |
| CAPAEKBJ_6 | 1.0 | 0.0 | 1.0 |
| CAPAEKBJ_7 | 0.0 | 1.0 | 0.0 |
| CAPAEKBJ_8 | 0.0 | 1.0 | 0.0 |
| CAPAEKBJ_10 | 0.0 | 1.0 | 0.0 |
| CAPAEKBJ_11 | 0.0 | 1.0 | 0.0 |
| CAPAEKBJ_19 | 1.0 | 0.0 | 1.0 |
| CAPAEKBJ_30 | 0.0 | 1.0 | 0.0 |
| CAPAEKBJ_34 | 0.0 | 1.0 | 0.0 |
| CAPAEKBJ_35 | 0.0 | 1.0 | 0.0 |
| CAPAEKBJ_36 | 0.0 | 1.0 | 0.0 |
| CAPAEKBJ_37 | 0.0 | 1.0 | 0.0 |
| CAPAEKBJ_38 | 0.0 | 1.0 | 0.0 |
| CAPAEKBJ_39 | 1.0 | 0.0 | 1.0 |
| CAPAEKBJ_40 | 0.0 | 1.0 | 0.0 |
| CAPAEKBJ_41 | 0.0 | 1.0 | 0.0 |
| CAPAEKBJ_42 | 0.0 | 1.0 | 0.0 |
| CAPAEKBJ_43 | 0.0 | 1.0 | 0.0 |
| CAPAEKBJ_44 | 0.0 | 1.0 | 0.0 |
| CAPAEKBJ_45 | 0.0 | 1.0 | 0.0 |
| CAPAEKBJ_46 | 0.0 | 1.0 | 0.0 |
| CAPAEKBJ_47 | 1.0 | 0.0 | 1.0 |
| CAPAEKBJ_49 | 0.0 | 1.0 | 0.0 |
| CAPAEKBJ_50 | 0.0 | 1.0 | 0.0 |
| CAPAEKBJ_51 | 0.0 | 1.0 | 0.0 |
| CAPAEKBJ_52 | 1.0 | 0.0 | 1.0 |
| CAPAEKBJ_53 | 0.0 | 1.0 | 0.0 |
| CAPAEKBJ_55 | 0.0 | 1.0 | 0.0 |
| CAPAEKBJ_60 | 0.0 | 1.0 | 0.0 |
| CAPAEKBJ_62 | 0.0 | 1.0 | 0.0 |
| CAPAEKBJ_64 | 0.0 | 1.0 | 0.0 |
| CAPAEKBJ_66 | 1.0 | 0.0 | 1.0 |
| CAPAEKBJ_68 | 0.0 | 1.0 | 0.0 |
| CAPAEKBJ_70 | 0.0 | 1.0 | 0.0 |
| CAPAEKBJ_71 | 0.0 | 1.0 | 0.0 |
| CAPAEKBJ_74 | 1.0 | 0.0 | 1.0 |
| CAPAEKBJ_79 | 0.0 | 1.0 | 0.0 |
| CAPAEKBJ_84 | 0.0 | 1.0 | 0.0 |
| CAPAEKBJ_86 | 0.0 | 1.0 | 0.0 |
| CAPAEKBJ_88 | 0.0 | 1.0 | 0.0 |
| CAPAEKBJ_90 | 0.0 | 1.0 | 0.0 |
| CAPAEKBJ_92 | 0.0 | 1.0 | 0.0 |
| CAPAEKBJ_93 | 0.0 | 1.0 | 0.0 |
| CAPAEKBJ_94 | 0.0 | 1.0 | 0.0 |
| CAPAEKBJ_95 | 0.0 | 1.0 | 0.0 |
| CAPAEKBJ_96 | 0.0 | 1.0 | 0.0 |
| CAPAEKBJ_97 | 0.0 | 1.0 | 0.0 |
| CAPAEKBJ_98 | 0.0 | 1.0 | 0.0 |
| CAPAEKBJ_99 | 0.0 | 1.0 | 0.0 |
| CAPAEKBJ_100 | 0.0 | 1.0 | 0.0 |
| CAPAEKBJ_101 | 0.0 | 1.0 | 0.0 |
| CAPAEKBJ_102 | 0.0 | 1.0 | 0.0 |
| CAPAEKBJ_103 | 0.0 | 1.0 | 0.0 |
| CAPAEKBJ_104 | 0.0 | 1.0 | 0.0 |
| CAPAEKBJ_105 | 0.0 | 1.0 | 0.0 |
| CAPAEKBJ_106 | 0.0 | 1.0 | 0.0 |
| CAPAEKBJ_107 | 0.0 | 1.0 | 0.0 |
| CAPAEKBJ_108 | 0.0 | 1.0 | 0.0 |
| CAPAEKBJ_109 | 0.0 | 1.0 | 0.0 |
| CAPAEKBJ_110 | 1.0 | 0.0 | 1.0 |
| CAPAEKBJ_111 | 1.0 | 0.0 | 1.0 |
| CAPAEKBJ_112 | 0.0 | 1.0 | 0.0 |
PlasmidHunter v 1.4.5 (Database: May. 2024 release)
Prophage
Phigaro
| Query ID | Begin | End | Transposable | Taxonomy | pVOGs |
|---|---|---|---|---|---|
| No hit found | |||||
Phigaro v2.4.0 (Database: Jan. 2024 release)