Probiotic potential risk score
| ARGs | VFs | PGs | PPRS |
|---|---|---|---|
| 0 | 21 | 32 | 38.28 |
PPRS is classified as low-risk (≤4), medium-risk (4-6), and high-risk (≥6).
Antibiotic resistance genes
Comprehensive Antibiotic Resistance Database (CARD)
| Query ID | Begin | End | ARO name | ARO accession | CARD name | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
RGI v6.0.3 (Database: CARD Variants v4.0.2, Nov. 2023 release)
ResFinder
| Query ID | Begin | End | Resistance gene | Phenotype | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|
| No hit found | |||||||
ResFinder v4.6.0 (Database: resfinder_db, Aug. 2024 release)
AMRFinderPlus
| Query ID | Begin | End | Gene symbol | Sequence name | Method | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
AMRFinderPlus v4.0.3 (Database: Oct. 2024 release)
Virulence factors
Virulence Factor Database (VFDB)
| Query ID | qstart | qend | Gene name | e-value | VF name | VF category | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|---|
| GIEFCPCP_13 | 52077 | 52867 | cshA | 0.0 | Cell surface hydrophobicity proteins | Adherence | 100.00 | 100.00 | - |
| GIEFCPCP_67 | 19727 | 20578 | rfbD | 0.0 | Capsule | Immune modulation | 100.00 | 100.00 | WP_014621820 |
| GIEFCPCP_13 | 96897 | 97490 | STU_RS15260 | 0.0 | Capsule | Immune modulation | 100.00 | 100.00 | WP_011226149 |
| GIEFCPCP_67 | 14130 | 15086 | STU_RS16250 | 0.0 | Capsule | Immune modulation | 100.00 | 100.00 | WP_011226328 |
| GIEFCPCP_67 | 9276 | 11060 | STU_RS16230 | 0.0 | Capsule | Immune modulation | 99.89 | 100.00 | WP_011226325 |
| GIEFCPCP_67 | 13337 | 14146 | STU_RS16245 | 0.0 | Capsule | Immune modulation | 99.88 | 100.00 | WP_002948020 |
| GIEFCPCP_23 | 12012 | 13466 | STR_RS05265 | 0.0 | Capsule | Immune modulation | 99.86 | 100.00 | WP_041827043 |
| GIEFCPCP_13 | 96897 | 97490 | STR_RS05880 | 0.0 | Capsule | Immune modulation | 99.83 | 100.00 | WP_011226149 |
| GIEFCPCP_13 | 132257 | 133018 | srtA | 0.0 | Sortase A | Exoenzyme | 99.74 | 100.00 | - |
| GIEFCPCP_67 | 15083 | 16231 | STU_RS16255 | 0.0 | Capsule | Immune modulation | 99.74 | 100.00 | WP_041828290 |
| GIEFCPCP_67 | 11057 | 12112 | STU_RS16235 | 0.0 | Capsule | Immune modulation | 99.72 | 100.00 | WP_002948022 |
| GIEFCPCP_9 | 12995 | 14653 | fbp54 | 0.0 | FBPs | Adherence | 99.70 | 100.00 | WP_011227179 |
| GIEFCPCP_67 | 16340 | 17350 | STU_RS16260 | 0.0 | Capsule | Immune modulation | 99.70 | 100.00 | WP_011226330 |
| GIEFCPCP_13 | 96897 | 97490 | STER_RS06030 | 0.0 | Capsule | Immune modulation | 99.66 | 100.00 | WP_011226149 |
| GIEFCPCP_13 | 97490 | 98359 | rfbA | 0.0 | Capsule | Immune modulation | 99.54 | 100.00 | WP_011681286 |
| GIEFCPCP_67 | 12132 | 13337 | STU_RS16240 | 0.0 | Capsule | Immune modulation | 99.42 | 100.00 | WP_011226326 |
| GIEFCPCP_2 | 18948 | 19916 | cbpD | 0.0 | Autolysin | Exoenzyme | 98.66 | 100.00 | WP_082302295 |
| GIEFCPCP_23 | 12012 | 13466 | STU_RS14650 | 0.0 | Capsule | Immune modulation | 97.94 | 100.00 | WP_011226049 |
| GIEFCPCP_67 | 17350 | 18624 | STU_RS16265 | 0.0 | Capsule | Immune modulation | 97.57 | 100.00 | WP_011226331 |
| GIEFCPCP_23 | 12012 | 13466 | STER_RS05320 | 0.0 | Capsule | Immune modulation | 96.92 | 99.79 | WP_011681177 |
| GIEFCPCP_66 | 107050 | 108353 | eno | 0.0 | Streptococcal enolase | Exoenzyme | 88.09 | 99.54 | WP_000022832 |
| GIEFCPCP_26 | 226 | 1236 | plr/gapA | 0.0 | Streptococcal plasmin receptor/GAPDH | Adherence | 86.92 | 99.51 | WP_002986042 |
| GIEFCPCP_13 | 95421 | 96467 | rfbB | 0.0 | Capsule | Immune modulation | 80.71 | 100.00 | WP_009659423 |
| GIEFCPCP_28 | 2308 | 3591 | tig/ropA | 0.0 | Trigger factor | Stress survival | 80.58 | 99.77 | WP_000107753 |
| GIEFCPCP_23 | 16854 | 17437 | SPD_RS01775 | 1.18e-148 | Capsule | Immune modulation | 83.08 | 96.20 | WP_001819836 |
| GIEFCPCP_23 | 13467 | 13931 | STR_RS05260 | 0.0 | Capsule | Immune modulation | 99.78 | 63.52 | WP_011227248 |
| GIEFCPCP_23 | 13467 | 13931 | STU_RS14645 | 0.0 | Capsule | Immune modulation | 98.28 | 63.52 | WP_011226048 |
| GIEFCPCP_23 | 13467 | 13931 | STER_RS05315 | 0.0 | Capsule | Immune modulation | 97.20 | 63.52 | WP_011681176 |
BLASTN v2.16.0 (Database: VFDB, Dec. 2024 release)
VirulenceFinder
| Query ID | Begin | End | Database | Virulence factor | Protein function | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
VirulenceFinder v2.0. 4 (Database: virulencefinder_db, Feb . 2024 release)
Pathogenic genes
PHI-base
| Query ID | qstart | qend | Gene name | e-value | Function | Identity | Coverage | Gene ID |
|---|---|---|---|---|---|---|---|---|
| GIEFCPCP_13 | 135705 | 136688 | ldh(Sp_1220) | 0.0 | L-lactate dehydrogenase | 94.82 | 100.00 | AAK75326 |
| GIEFCPCP_65 | 14017 | 12944 | MntE | 0.0 | manganese homeostasis | 94.41 | 99.72 | ABF32167 |
| GIEFCPCP_66 | 24814 | 25782 | spr0084 | 0.0 | pathogenitcity related | 93.19 | 98.48 | AAK98888 |
| GIEFCPCP_67 | 183769 | 186072 | pfl2(Sp_0459) | 0.0 | formate acetyltransferase | 92.97 | 99.22 | AAK74619 |
| GIEFCPCP_71 | 11330 | 9084 | metE | 0.0 | methionine biosynthesis enzymes | 91.99 | 100.00 | AAK74738 |
| GIEFCPCP_27 | 18775 | 20256 | SPD_0310 | 0.0 | UPF0371 protein SPD_0310 | 91.90 | 100.00 | ABJ54480 |
| GIEFCPCP_55 | 12166 | 13158 | recA | 0.0 | DNA recombination and repair | 91.24 | 85.31 | AAL00560 |
| GIEFCPCP_75 | 119 | 1090 | prsA2 | 0.0 | ribose-phosphate pyrophosphokinase | 90.12 | 100.00 | ABF36968 |
| GIEFCPCP_67 | 70029 | 68878 | potA | 0.0 | ABC transporter ATP-binding protein-spermidine/putrescine transport | 89.06 | 99.74 | AAL00050 |
| GIEFCPCP_67 | 35560 | 33578 | uvrB | 0.0 | excinuclease ABC, B subunit | 88.96 | 99.70 | AE014259_2 |
| GIEFCPCP_13 | 119510 | 117780 | ptsI | 0.0 | phosphoenolpyruvate-protein phosphotransferase | 87.87 | 100.00 | AAK34199 |
| GIEFCPCP_31 | 29825 | 28347 | IMPDH | 0.0 | inosine-5'-monophosphate dehydrogenase | 87.42 | 100.00 | ADE32434 |
| GIEFCPCP_66 | 107050 | 108351 | Eno | 0.0 | enolase | 86.21 | 99.77 | ABP90468 |
| GIEFCPCP_31 | 15089 | 13197 | gidA | 0.0 | tRNA uridine 5-carboxymethylaminomethyl modification enzyme | 85.89 | 98.90 | ABP91129 |
| GIEFCPCP_71 | 6159 | 7868 | PGM | 0.0 | phosphoglucomutase | 83.89 | 99.65 | ACH87041 |
| GIEFCPCP_15 | 18849 | 19859 | pdh | 0.0 | pyruvate dehydrogenase | 83.09 | 99.70 | ABP91006 |
| GIEFCPCP_1 | 7433 | 6072 | mnmE | 0.0 | central tRNA-modifying GTPase | 82.02 | 99.56 | ABP90420 |
| GIEFCPCP_51 | 4703 | 6595 | PepO | 0.0 | endopeptidase | 80.03 | 100.00 | ABF32980 |
| GIEFCPCP_66 | 92621 | 93511 | bglB | 1.25e-179 | putative phospho--glucosidase | 88.89 | 99.66 | AAK33487 |
| GIEFCPCP_7 | 13232 | 12294 | SP_0676 | 3.90e-169 | transcription facot | 81.47 | 97.20 | AAK74821 |
| GIEFCPCP_71 | 8892 | 8035 | metF | 1.15e-166 | methionine biosynthesis enzymes | 86.36 | 99.31 | AAK74739 |
| GIEFCPCP_13 | 24452 | 23748 | covR | 5.79e-132 | responder protein | 85.53 | 100.00 | AAK71319 |
| GIEFCPCP_62 | 6891 | 7562 | rr01 | 8.26e-127 | response regulator | 83.93 | 99.56 | CAB54566 |
| GIEFCPCP_13 | 24452 | 23748 | walR | 2.74e-122 | DNA-binding response regulator | 81.70 | 100.00 | ANC99504 |
| GIEFCPCP_42 | 48999 | 49685 | CovR | 3.18e-119 | serves to repress GAS virulence factor-encoding genes | 80.79 | 100.00 | ACE75886 |
| GIEFCPCP_71 | 2205 | 1537 | CiaR | 9.52e-119 | two-component response regulator | 83.86 | 99.55 | AAK74935 |
| GIEFCPCP_71 | 2205 | 1534 | ciaR | 9.46e-117 | two component system response regulator | 81.70 | 99.12 | AIK75708 |
| GIEFCPCP_55 | 13455 | 13850 | SpxA2 | 2.80e-76 | transcriptional regulator | 90.91 | 100.00 | ERL21461 |
| GIEFCPCP_80 | 13393 | 13680 | spr0479 | 3.36e-49 | essential gene | 86.46 | 98.97 | AAK99283 |
| GIEFCPCP_2 | 60881 | 61135 | spr1327 | 1.05e-45 | essential gene | 95.29 | 100.00 | AAL00131 |
| GIEFCPCP_4 | 14622 | 14885 | spr0175 | 1.59e-42 | pathogenitcity related | 84.09 | 100.00 | AAK98979 |
| GIEFCPCP_4 | 15449 | 15715 | spr0177 | 4.10e-34 | essential gene | 84.27 | 88.12 | AAK98981 |
| GIEFCPCP_28 | 3749 | 4249 | RopE (M5005_Spy_1611) | 3.41e-76 | probable DNA-directed RNA polymerase subunit delta | 80.84 | 87.43 | AAK34603 |
| GIEFCPCP_67 | 183769 | 186066 | PFL (B9H01_RS01125) | 0.0 | formate C-acetyltransferase | 82.94 | 98.08 | MYN69560 |
| GIEFCPCP_51 | 19164 | 20183 | ilvC (SPD_0406) | 0.0 | ketol-acid reductoisomerase (NADP(+)) | 96.18 | 100.00 | ABJ55451 |
BLASTX v2.16.0 (Database: PHI base v4.16, May. 2024 release)
Plasmid
PlasmidFinder
| Query ID | Begin | End | Plasmid | Query / Template | Identity | Accession no. |
|---|---|---|---|---|---|---|
| No hit found | ||||||
PlasmidFinder v 2.1.6 (Database: plasmidfinder_db v 2.2.0 , Nov. 2024 release)
PlasmidHunter
| Query ID | Prediction | Chromosome | Plasmid |
|---|---|---|---|
| GIEFCPCP_1 | 0.0 | 1.0 | 0.0 |
| GIEFCPCP_2 | 0.0 | 1.0 | 0.0 |
| GIEFCPCP_3 | 0.0 | 1.0 | 0.0 |
| GIEFCPCP_4 | 0.0 | 1.0 | 0.0 |
| GIEFCPCP_5 | 0.0 | 1.0 | 0.0 |
| GIEFCPCP_6 | 0.0 | 1.0 | 0.0 |
| GIEFCPCP_7 | 0.0 | 1.0 | 0.0 |
| GIEFCPCP_8 | 0.0 | 1.0 | 0.0 |
| GIEFCPCP_9 | 0.0 | 1.0 | 0.0 |
| GIEFCPCP_10 | 0.0 | 1.0 | 0.0 |
| GIEFCPCP_11 | 0.0 | 1.0 | 0.0 |
| GIEFCPCP_12 | 0.0 | 1.0 | 0.0 |
| GIEFCPCP_13 | 0.0 | 1.0 | 0.0 |
| GIEFCPCP_14 | 0.0 | 1.0 | 0.0 |
| GIEFCPCP_15 | 0.0 | 1.0 | 0.0 |
| GIEFCPCP_16 | 0.0 | 1.0 | 0.0 |
| GIEFCPCP_18 | 0.0 | 1.0 | 0.0 |
| GIEFCPCP_19 | 0.0 | 1.0 | 0.0 |
| GIEFCPCP_20 | 0.0 | 1.0 | 0.0 |
| GIEFCPCP_22 | 1.0 | 0.0 | 1.0 |
| GIEFCPCP_23 | 0.0 | 1.0 | 0.0 |
| GIEFCPCP_24 | 0.0 | 1.0 | 0.0 |
| GIEFCPCP_25 | 0.0 | 1.0 | 0.0 |
| GIEFCPCP_26 | 0.0 | 1.0 | 0.0 |
| GIEFCPCP_27 | 0.0 | 1.0 | 0.0 |
| GIEFCPCP_28 | 0.0 | 1.0 | 0.0 |
| GIEFCPCP_29 | 1.0 | 0.0 | 1.0 |
| GIEFCPCP_30 | 0.0 | 1.0 | 0.0 |
| GIEFCPCP_31 | 0.0 | 1.0 | 0.0 |
| GIEFCPCP_33 | 0.0 | 1.0 | 0.0 |
| GIEFCPCP_35 | 1.0 | 0.0 | 1.0 |
| GIEFCPCP_38 | 0.0 | 1.0 | 0.0 |
| GIEFCPCP_40 | 0.0 | 1.0 | 0.0 |
| GIEFCPCP_41 | 0.0 | 1.0 | 0.0 |
| GIEFCPCP_42 | 0.0 | 1.0 | 0.0 |
| GIEFCPCP_45 | 0.0 | 1.0 | 0.0 |
| GIEFCPCP_46 | 0.0 | 1.0 | 0.0 |
| GIEFCPCP_51 | 0.0 | 1.0 | 0.0 |
| GIEFCPCP_55 | 0.0 | 1.0 | 0.0 |
| GIEFCPCP_62 | 0.0 | 1.0 | 0.0 |
| GIEFCPCP_64 | 0.0 | 1.0 | 0.0 |
| GIEFCPCP_65 | 0.0 | 1.0 | 0.0 |
| GIEFCPCP_66 | 0.0 | 1.0 | 0.0 |
| GIEFCPCP_67 | 0.0 | 1.0 | 0.0 |
| GIEFCPCP_68 | 0.0 | 1.0 | 0.0 |
| GIEFCPCP_70 | 0.0 | 1.0 | 0.0 |
| GIEFCPCP_71 | 0.0 | 1.0 | 0.0 |
| GIEFCPCP_73 | 0.0 | 1.0 | 0.0 |
| GIEFCPCP_74 | 0.0 | 1.0 | 0.0 |
| GIEFCPCP_75 | 0.0 | 1.0 | 0.0 |
| GIEFCPCP_78 | 0.0 | 1.0 | 0.0 |
| GIEFCPCP_80 | 0.0 | 1.0 | 0.0 |
| GIEFCPCP_81 | 0.0 | 1.0 | 0.0 |
| GIEFCPCP_82 | 0.0 | 1.0 | 0.0 |
| GIEFCPCP_83 | 0.0 | 1.0 | 0.0 |
| GIEFCPCP_85 | 0.0 | 1.0 | 0.0 |
PlasmidHunter v 1.4.5 (Database: May. 2024 release)
Prophage
Phigaro
| Query ID | Begin | End | Transposable | Taxonomy | pVOGs |
|---|---|---|---|---|---|
| No hit found | |||||
Phigaro v2.4.0 (Database: Jan. 2024 release)