Probiotic potential risk score
| ARGs | VFs | PGs | PPRS |
|---|---|---|---|
| 0 | 18 | 33 | 37.59 |
PPRS is classified as low-risk (≤4), medium-risk (4-6), and high-risk (≥6).
Antibiotic resistance genes
Comprehensive Antibiotic Resistance Database (CARD)
| Query ID | Begin | End | ARO name | ARO accession | CARD name | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
RGI v6.0.3 (Database: CARD Variants v4.0.2, Nov. 2023 release)
ResFinder
| Query ID | Begin | End | Resistance gene | Phenotype | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|
| No hit found | |||||||
ResFinder v4.6.0 (Database: resfinder_db, Aug. 2024 release)
AMRFinderPlus
| Query ID | Begin | End | Gene symbol | Sequence name | Method | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
AMRFinderPlus v4.0.3 (Database: Oct. 2024 release)
Virulence factors
Virulence Factor Database (VFDB)
| Query ID | qstart | qend | Gene name | e-value | VF name | VF category | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|---|
| LAJCEHDN_26 | 9712 | 10581 | rfbA | 0.0 | Capsule | Immune modulation | 100.00 | 100.00 | WP_011681286 |
| LAJCEHDN_26 | 9119 | 9712 | STER_RS06030 | 0.0 | Capsule | Immune modulation | 100.00 | 100.00 | WP_011226149 |
| LAJCEHDN_26 | 9119 | 9712 | STR_RS05880 | 0.0 | Capsule | Immune modulation | 99.83 | 100.00 | WP_011226149 |
| LAJCEHDN_26 | 9119 | 9712 | STU_RS15260 | 0.0 | Capsule | Immune modulation | 99.66 | 100.00 | WP_011226149 |
| LAJCEHDN_53 | 68695 | 70353 | fbp54 | 0.0 | FBPs | Adherence | 99.58 | 100.00 | WP_011227179 |
| LAJCEHDN_42 | 9133 | 9972 | cbpD | 0.0 | Autolysin | Exoenzyme | 99.52 | 100.00 | WP_011226733 |
| LAJCEHDN_51 | 13904 | 14635 | STER_RS05315 | 0.0 | Capsule | Immune modulation | 98.77 | 100.00 | WP_011681176 |
| LAJCEHDN_43 | 52122 | 52910 | cshA | 0.0 | Cell surface hydrophobicity proteins | Adherence | 98.36 | 99.75 | - |
| LAJCEHDN_40 | 28868 | 29584 | STER_RS07085 | 0.0 | Capsule | Immune modulation | 98.33 | 100.00 | WP_011681442 |
| LAJCEHDN_51 | 13904 | 14635 | STU_RS14645 | 0.0 | Capsule | Immune modulation | 98.09 | 100.00 | WP_011226048 |
| LAJCEHDN_51 | 13904 | 14635 | STR_RS05260 | 0.0 | Capsule | Immune modulation | 97.81 | 100.00 | WP_011227248 |
| LAJCEHDN_51 | 12453 | 13193 | STER_RS05305 | 0.0 | Capsule | Immune modulation | 97.71 | 100.00 | WP_011681174 |
| LAJCEHDN_40 | 35206 | 36057 | rfbD | 0.0 | Capsule | Immune modulation | 97.65 | 100.00 | WP_014621820 |
| LAJCEHDN_65 | 2942 | 3703 | srtA | 0.0 | Sortase A | Exoenzyme | 97.64 | 100.00 | - |
| LAJCEHDN_51 | 14636 | 16091 | STER_RS05320 | 0.0 | Capsule | Immune modulation | 97.60 | 99.66 | WP_011681177 |
| LAJCEHDN_51 | 12453 | 13193 | STU_RS14635 | 0.0 | Capsule | Immune modulation | 97.57 | 100.00 | WP_011226046 |
| LAJCEHDN_51 | 12458 | 13193 | STR_RS05250 | 0.0 | Capsule | Immune modulation | 97.01 | 98.13 | WP_011227246 |
| LAJCEHDN_51 | 14636 | 16091 | STU_RS14650 | 0.0 | Capsule | Immune modulation | 96.84 | 99.86 | WP_011226049 |
| LAJCEHDN_40 | 27746 | 28522 | STER_RS07075 | 0.0 | Capsule | Immune modulation | 96.66 | 99.87 | WP_011681440 |
| LAJCEHDN_51 | 14636 | 16091 | STR_RS05265 | 0.0 | Capsule | Immune modulation | 96.08 | 99.86 | WP_041827043 |
| LAJCEHDN_51 | 11031 | 12396 | STER_RS05300 | 0.0 | Capsule | Immune modulation | 95.24 | 99.85 | WP_011681173 |
| LAJCEHDN_51 | 11029 | 12396 | STU_RS14630 | 0.0 | Capsule | Immune modulation | 94.30 | 100.00 | WP_011226045 |
| LAJCEHDN_51 | 13203 | 13895 | STU_RS14640 | 0.0 | Capsule | Immune modulation | 93.51 | 100.00 | WP_011226047 |
| LAJCEHDN_51 | 13203 | 13895 | STR_RS05255 | 0.0 | Capsule | Immune modulation | 93.22 | 100.00 | WP_011227247 |
| LAJCEHDN_41 | 73183 | 74486 | eno | 0.0 | Streptococcal enolase | Exoenzyme | 88.10 | 99.46 | WP_000022832 |
| LAJCEHDN_51 | 13203 | 13895 | STER_RS05310 | 0.0 | Capsule | Immune modulation | 87.16 | 100.00 | WP_011681175 |
| LAJCEHDN_63 | 92 | 1102 | plr/gapA | 0.0 | Streptococcal plasmin receptor/GAPDH | Adherence | 86.54 | 99.41 | WP_002986042 |
| LAJCEHDN_87 | 2309 | 3592 | tig/ropA | 0.0 | Trigger factor | Stress survival | 80.65 | 99.77 | WP_000107753 |
| LAJCEHDN_26 | 7644 | 8690 | rfbB | 0.0 | Capsule | Immune modulation | 80.61 | 100.00 | WP_009659423 |
BLASTN v2.16.0 (Database: VFDB, Dec. 2024 release)
VirulenceFinder
| Query ID | Begin | End | Database | Virulence factor | Protein function | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
VirulenceFinder v2.0. 4 (Database: virulencefinder_db, Feb . 2024 release)
Pathogenic genes
PHI-base
| Query ID | qstart | qend | Gene name | e-value | Function | Identity | Coverage | Gene ID |
|---|---|---|---|---|---|---|---|---|
| LAJCEHDN_65 | 6390 | 7373 | ldh(Sp_1220) | 0.0 | L-lactate dehydrogenase | 94.82 | 100.00 | AAK75326 |
| LAJCEHDN_77 | 13878 | 12805 | MntE | 0.0 | manganese homeostasis | 94.41 | 99.72 | ABF32167 |
| LAJCEHDN_41 | 158171 | 157203 | spr0084 | 0.0 | pathogenitcity related | 93.19 | 98.48 | AAK98888 |
| LAJCEHDN_40 | 199869 | 202172 | pfl2(Sp_0459) | 0.0 | formate acetyltransferase | 92.84 | 99.22 | AAK74619 |
| LAJCEHDN_48 | 21340 | 23586 | metE | 0.0 | methionine biosynthesis enzymes | 91.99 | 100.00 | AAK74738 |
| LAJCEHDN_60 | 12695 | 11214 | SPD_0310 | 0.0 | UPF0371 protein SPD_0310 | 91.90 | 100.00 | ABJ54480 |
| LAJCEHDN_57 | 2059 | 1067 | recA | 0.0 | DNA recombination and repair | 91.24 | 85.31 | AAL00560 |
| LAJCEHDN_72 | 15483 | 14512 | prsA2 | 0.0 | ribose-phosphate pyrophosphokinase | 90.12 | 100.00 | ABF36968 |
| LAJCEHDN_40 | 86077 | 84926 | potA | 0.0 | ABC transporter ATP-binding protein-spermidine/putrescine transport | 89.32 | 99.74 | AAL00050 |
| LAJCEHDN_40 | 49117 | 47129 | uvrB | 0.0 | excinuclease ABC, B subunit | 88.99 | 100.00 | AE014259_2 |
| LAJCEHDN_88 | 9898 | 11628 | ptsI | 0.0 | phosphoenolpyruvate-protein phosphotransferase | 88.04 | 100.00 | AAK34199 |
| LAJCEHDN_56 | 80229 | 78751 | IMPDH | 0.0 | inosine-5'-monophosphate dehydrogenase | 87.42 | 100.00 | ADE32434 |
| LAJCEHDN_41 | 74486 | 73185 | Eno | 0.0 | enolase | 86.21 | 99.77 | ABP90468 |
| LAJCEHDN_56 | 65040 | 63148 | gidA | 0.0 | tRNA uridine 5-carboxymethylaminomethyl modification enzyme | 86.05 | 98.90 | ABP91129 |
| LAJCEHDN_48 | 26511 | 24802 | PGM | 0.0 | phosphoglucomutase | 84.06 | 99.65 | ACH87041 |
| LAJCEHDN_58 | 54990 | 53980 | pdh | 0.0 | pyruvate dehydrogenase | 83.09 | 99.70 | ABP91006 |
| LAJCEHDN_53 | 46697 | 48058 | mnmE | 0.0 | central tRNA-modifying GTPase | 82.24 | 99.56 | ABP90420 |
| LAJCEHDN_58 | 4720 | 6612 | PepO | 0.0 | endopeptidase | 80.03 | 100.00 | ABF32980 |
| LAJCEHDN_41 | 88921 | 88031 | bglB | 4.87e-179 | putative phospho--glucosidase | 88.55 | 99.66 | AAK33487 |
| LAJCEHDN_66 | 3938 | 3000 | SP_0676 | 6.25e-169 | transcription facot | 81.15 | 97.20 | AAK74821 |
| LAJCEHDN_48 | 23778 | 24635 | metF | 4.14e-166 | methionine biosynthesis enzymes | 86.36 | 99.31 | AAK74739 |
| LAJCEHDN_43 | 24442 | 23738 | covR | 2.28e-132 | responder protein | 85.53 | 100.00 | AAK71319 |
| LAJCEHDN_60 | 44754 | 45425 | rr01 | 1.11e-125 | response regulator | 83.93 | 99.56 | CAB54566 |
| LAJCEHDN_48 | 30465 | 31133 | CiaR | 7.57e-125 | two-component response regulator | 87.00 | 99.55 | AAK74935 |
| LAJCEHDN_48 | 30465 | 31136 | ciaR | 7.38e-123 | two component system response regulator | 84.82 | 99.12 | AIK75708 |
| LAJCEHDN_43 | 24442 | 23738 | walR | 9.61e-123 | DNA-binding response regulator | 82.13 | 100.00 | ANC99504 |
| LAJCEHDN_47 | 16139 | 16825 | CovR | 1.29e-119 | serves to repress GAS virulence factor-encoding genes | 80.79 | 100.00 | ACE75886 |
| LAJCEHDN_57 | 755 | 360 | SpxA2 | 3.65e-76 | transcriptional regulator | 90.91 | 100.00 | ERL21461 |
| LAJCEHDN_53 | 35338 | 34937 | SpxA1 | 1.69e-67 | transcriptional regulator | 80.60 | 100.00 | ERL19273 |
| LAJCEHDN_81 | 25610 | 25323 | spr0479 | 2.96e-49 | essential gene | 86.46 | 98.97 | AAK99283 |
| LAJCEHDN_76 | 60824 | 61078 | spr1327 | 1.24e-45 | essential gene | 95.29 | 100.00 | AAL00131 |
| LAJCEHDN_56 | 31396 | 31659 | spr0175 | 4.13e-42 | pathogenitcity related | 84.09 | 100.00 | AAK98979 |
| LAJCEHDN_56 | 32223 | 32489 | spr0177 | 9.03e-34 | essential gene | 84.27 | 88.12 | AAK98981 |
| LAJCEHDN_87 | 3750 | 4250 | RopE (M5005_Spy_1611) | 1.66e-76 | probable DNA-directed RNA polymerase subunit delta | 81.44 | 87.43 | AAK34603 |
| LAJCEHDN_40 | 199869 | 202166 | PFL (B9H01_RS01125) | 0.0 | formate C-acetyltransferase | 82.81 | 98.08 | MYN69560 |
| LAJCEHDN_58 | 19128 | 20147 | ilvC (SPD_0406) | 0.0 | ketol-acid reductoisomerase (NADP(+)) | 95.88 | 100.00 | ABJ55451 |
BLASTX v2.16.0 (Database: PHI base v4.16, May. 2024 release)
Plasmid
PlasmidFinder
| Query ID | Begin | End | Plasmid | Query / Template | Identity | Accession no. |
|---|---|---|---|---|---|---|
| No hit found | ||||||
PlasmidFinder v 2.1.6 (Database: plasmidfinder_db v 2.2.0 , Nov. 2024 release)
PlasmidHunter
| Query ID | Prediction | Chromosome | Plasmid |
|---|---|---|---|
| LAJCEHDN_3 | 1.0 | 0.0 | 1.0 |
| LAJCEHDN_8 | 0.0 | 1.0 | 0.0 |
| LAJCEHDN_10 | 1.0 | 0.0 | 1.0 |
| LAJCEHDN_12 | 0.0 | 1.0 | 0.0 |
| LAJCEHDN_26 | 0.0 | 1.0 | 0.0 |
| LAJCEHDN_29 | 0.0 | 1.0 | 0.0 |
| LAJCEHDN_40 | 0.0 | 1.0 | 0.0 |
| LAJCEHDN_41 | 0.0 | 1.0 | 0.0 |
| LAJCEHDN_42 | 0.0 | 1.0 | 0.0 |
| LAJCEHDN_43 | 0.0 | 1.0 | 0.0 |
| LAJCEHDN_44 | 0.0 | 1.0 | 0.0 |
| LAJCEHDN_45 | 0.0 | 1.0 | 0.0 |
| LAJCEHDN_46 | 0.0 | 1.0 | 0.0 |
| LAJCEHDN_47 | 0.0 | 1.0 | 0.0 |
| LAJCEHDN_48 | 0.0 | 1.0 | 0.0 |
| LAJCEHDN_49 | 0.0 | 1.0 | 0.0 |
| LAJCEHDN_50 | 0.0 | 1.0 | 0.0 |
| LAJCEHDN_51 | 0.0 | 1.0 | 0.0 |
| LAJCEHDN_52 | 0.0 | 1.0 | 0.0 |
| LAJCEHDN_53 | 0.0 | 1.0 | 0.0 |
| LAJCEHDN_54 | 0.0 | 1.0 | 0.0 |
| LAJCEHDN_56 | 0.0 | 1.0 | 0.0 |
| LAJCEHDN_57 | 0.0 | 1.0 | 0.0 |
| LAJCEHDN_58 | 0.0 | 1.0 | 0.0 |
| LAJCEHDN_60 | 0.0 | 1.0 | 0.0 |
| LAJCEHDN_61 | 0.0 | 1.0 | 0.0 |
| LAJCEHDN_62 | 0.0 | 1.0 | 0.0 |
| LAJCEHDN_63 | 0.0 | 1.0 | 0.0 |
| LAJCEHDN_64 | 0.0 | 1.0 | 0.0 |
| LAJCEHDN_65 | 0.0 | 1.0 | 0.0 |
| LAJCEHDN_66 | 0.0 | 1.0 | 0.0 |
| LAJCEHDN_67 | 1.0 | 0.0 | 1.0 |
| LAJCEHDN_68 | 0.0 | 1.0 | 0.0 |
| LAJCEHDN_69 | 0.0 | 1.0 | 0.0 |
| LAJCEHDN_70 | 1.0 | 0.0 | 1.0 |
| LAJCEHDN_72 | 0.0 | 1.0 | 0.0 |
| LAJCEHDN_74 | 0.0 | 1.0 | 0.0 |
| LAJCEHDN_75 | 1.0 | 0.0 | 1.0 |
| LAJCEHDN_76 | 0.0 | 1.0 | 0.0 |
| LAJCEHDN_77 | 0.0 | 1.0 | 0.0 |
| LAJCEHDN_78 | 0.0 | 1.0 | 0.0 |
| LAJCEHDN_79 | 0.0 | 1.0 | 0.0 |
| LAJCEHDN_80 | 0.0 | 1.0 | 0.0 |
| LAJCEHDN_81 | 0.0 | 1.0 | 0.0 |
| LAJCEHDN_82 | 0.0 | 1.0 | 0.0 |
| LAJCEHDN_83 | 0.0 | 1.0 | 0.0 |
| LAJCEHDN_84 | 0.0 | 1.0 | 0.0 |
| LAJCEHDN_85 | 0.0 | 1.0 | 0.0 |
| LAJCEHDN_86 | 1.0 | 0.0 | 1.0 |
| LAJCEHDN_87 | 0.0 | 1.0 | 0.0 |
| LAJCEHDN_88 | 0.0 | 1.0 | 0.0 |
| LAJCEHDN_90 | 0.0 | 1.0 | 0.0 |
| LAJCEHDN_93 | 0.0 | 1.0 | 0.0 |
| LAJCEHDN_94 | 1.0 | 0.0 | 1.0 |
| LAJCEHDN_106 | 0.0 | 1.0 | 0.0 |
PlasmidHunter v 1.4.5 (Database: May. 2024 release)
Prophage
Phigaro
| Query ID | Begin | End | Transposable | Taxonomy | pVOGs |
|---|---|---|---|---|---|
| No hit found | |||||
Phigaro v2.4.0 (Database: Jan. 2024 release)