Probiotic potential risk score
| ARGs | VFs | PGs | PPRS |
|---|---|---|---|
| 0 | 20 | 33 | 38.59 |
PPRS is classified as low-risk (≤4), medium-risk (4-6), and high-risk (≥6).
Antibiotic resistance genes
Comprehensive Antibiotic Resistance Database (CARD)
| Query ID | Begin | End | ARO name | ARO accession | CARD name | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
RGI v6.0.3 (Database: CARD Variants v4.0.2, Nov. 2023 release)
ResFinder
| Query ID | Begin | End | Resistance gene | Phenotype | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|
| No hit found | |||||||
ResFinder v4.6.0 (Database: resfinder_db, Aug. 2024 release)
AMRFinderPlus
| Query ID | Begin | End | Gene symbol | Sequence name | Method | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
AMRFinderPlus v4.0.3 (Database: Oct. 2024 release)
Virulence factors
Virulence Factor Database (VFDB)
| Query ID | qstart | qend | Gene name | e-value | VF name | VF category | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|---|
| CLCPEIHJ_101 | 9591 | 10460 | rfbA | 0.0 | Capsule | Immune modulation | 100.00 | 100.00 | WP_011681286 |
| CLCPEIHJ_101 | 8998 | 9591 | STER_RS06030 | 0.0 | Capsule | Immune modulation | 100.00 | 100.00 | WP_011226149 |
| CLCPEIHJ_99 | 157659 | 158627 | STER_RS07090 | 0.0 | Capsule | Immune modulation | 100.00 | 100.00 | WP_011681443 |
| CLCPEIHJ_101 | 8998 | 9591 | STR_RS05880 | 0.0 | Capsule | Immune modulation | 99.83 | 100.00 | WP_011226149 |
| CLCPEIHJ_101 | 8998 | 9591 | STU_RS15260 | 0.0 | Capsule | Immune modulation | 99.66 | 100.00 | WP_011226149 |
| CLCPEIHJ_53 | 13044 | 14702 | fbp54 | 0.0 | FBPs | Adherence | 99.58 | 100.00 | WP_011227179 |
| CLCPEIHJ_99 | 156664 | 157641 | STER_RS07095 | 0.0 | Capsule | Immune modulation | 99.39 | 100.00 | WP_011681444 |
| CLCPEIHJ_101 | 44360 | 45121 | srtA | 0.0 | Sortase A | Exoenzyme | 98.82 | 100.00 | - |
| CLCPEIHJ_59 | 1074 | 1814 | STU_RS14635 | 0.0 | Capsule | Immune modulation | 98.52 | 100.00 | WP_011226046 |
| CLCPEIHJ_59 | 1074 | 1814 | STER_RS05305 | 0.0 | Capsule | Immune modulation | 98.38 | 100.00 | WP_011681174 |
| CLCPEIHJ_112 | 817 | 1610 | cshA | 0.0 | Cell surface hydrophobicity proteins | Adherence | 98.36 | 100.25 | - |
| CLCPEIHJ_99 | 158628 | 159344 | STER_RS07085 | 0.0 | Capsule | Immune modulation | 98.19 | 100.00 | WP_011681442 |
| CLCPEIHJ_59 | 372 | 1064 | STR_RS05255 | 0.0 | Capsule | Immune modulation | 98.12 | 100.00 | WP_011227247 |
| CLCPEIHJ_59 | 372 | 1064 | STU_RS14640 | 0.0 | Capsule | Immune modulation | 98.12 | 100.00 | WP_011226047 |
| CLCPEIHJ_59 | 1074 | 1809 | STR_RS05250 | 0.0 | Capsule | Immune modulation | 97.83 | 98.13 | WP_011227246 |
| CLCPEIHJ_51 | 46576 | 47535 | cbpD | 0.0 | Autolysin | Exoenzyme | 97.42 | 99.90 | WP_082302295 |
| CLCPEIHJ_99 | 154439 | 155290 | rfbD | 0.0 | Capsule | Immune modulation | 97.07 | 100.00 | WP_014621820 |
| CLCPEIHJ_99 | 159690 | 160460 | STER_RS07075 | 0.0 | Capsule | Immune modulation | 96.89 | 99.10 | WP_011681440 |
| CLCPEIHJ_99 | 155409 | 156667 | STER_RS07100 | 0.0 | Capsule | Immune modulation | 96.51 | 99.92 | WP_011681445 |
| CLCPEIHJ_59 | 1871 | 3238 | STU_RS14630 | 0.0 | Capsule | Immune modulation | 96.42 | 100.00 | WP_011226045 |
| CLCPEIHJ_59 | 1871 | 3236 | STER_RS05300 | 0.0 | Capsule | Immune modulation | 94.14 | 99.85 | WP_011681173 |
| CLCPEIHJ_59 | 372 | 1064 | STER_RS05310 | 0.0 | Capsule | Immune modulation | 89.90 | 100.00 | WP_011681175 |
| CLCPEIHJ_104 | 95732 | 97035 | eno | 0.0 | Streptococcal enolase | Exoenzyme | 88.10 | 99.46 | WP_000022832 |
| CLCPEIHJ_57 | 533 | 1543 | plr/gapA | 0.0 | Streptococcal plasmin receptor/GAPDH | Adherence | 87.46 | 99.80 | WP_002986042 |
| CLCPEIHJ_33 | 59453 | 60736 | tig/ropA | 0.0 | Trigger factor | Stress survival | 80.73 | 99.77 | WP_000107753 |
| CLCPEIHJ_101 | 7523 | 8569 | rfbB | 0.0 | Capsule | Immune modulation | 80.52 | 100.00 | WP_009659423 |
| CLCPEIHJ_68 | 2015 | 2598 | SPD_RS01775 | 1.35e-152 | Capsule | Immune modulation | 83.42 | 96.20 | WP_001819836 |
| CLCPEIHJ_32 | 249 | 713 | STR_RS05260 | 0.0 | Capsule | Immune modulation | 98.71 | 63.52 | WP_011227248 |
| CLCPEIHJ_32 | 249 | 713 | STER_RS05315 | 0.0 | Capsule | Immune modulation | 97.85 | 63.52 | WP_011681176 |
| CLCPEIHJ_32 | 249 | 713 | STU_RS14645 | 0.0 | Capsule | Immune modulation | 97.20 | 63.52 | WP_011226048 |
BLASTN v2.16.0 (Database: VFDB, Dec. 2024 release)
VirulenceFinder
| Query ID | Begin | End | Database | Virulence factor | Protein function | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
VirulenceFinder v2.0. 4 (Database: virulencefinder_db, Feb . 2024 release)
Pathogenic genes
PHI-base
| Query ID | qstart | qend | Gene name | e-value | Function | Identity | Coverage | Gene ID |
|---|---|---|---|---|---|---|---|---|
| CLCPEIHJ_101 | 47808 | 48791 | ldh(Sp_1220) | 0.0 | L-lactate dehydrogenase | 94.82 | 100.00 | AAK75326 |
| CLCPEIHJ_40 | 13756 | 12683 | MntE | 0.0 | manganese homeostasis | 94.41 | 99.72 | ABF32167 |
| CLCPEIHJ_104 | 12095 | 13063 | spr0084 | 0.0 | pathogenitcity related | 93.19 | 98.48 | AAK98888 |
| CLCPEIHJ_41 | 2286 | 4589 | pfl2(Sp_0459) | 0.0 | formate acetyltransferase | 92.97 | 99.22 | AAK74619 |
| CLCPEIHJ_114 | 47521 | 49002 | SPD_0310 | 0.0 | UPF0371 protein SPD_0310 | 92.31 | 100.00 | ABJ54480 |
| CLCPEIHJ_34 | 44060 | 41814 | metE | 0.0 | methionine biosynthesis enzymes | 91.72 | 100.00 | AAK74738 |
| CLCPEIHJ_107 | 2028 | 1030 | recA | 0.0 | DNA recombination and repair | 91.29 | 85.82 | AAL00560 |
| CLCPEIHJ_50 | 119 | 1090 | prsA2 | 0.0 | ribose-phosphate pyrophosphokinase | 90.12 | 100.00 | ABF36968 |
| CLCPEIHJ_99 | 113403 | 114554 | potA | 0.0 | ABC transporter ATP-binding protein-spermidine/putrescine transport | 89.06 | 99.74 | AAL00050 |
| CLCPEIHJ_99 | 141400 | 143388 | uvrB | 0.0 | excinuclease ABC, B subunit | 88.84 | 100.00 | AE014259_2 |
| CLCPEIHJ_101 | 31612 | 29882 | ptsI | 0.0 | phosphoenolpyruvate-protein phosphotransferase | 88.04 | 100.00 | AAK34199 |
| CLCPEIHJ_106 | 71620 | 70142 | IMPDH | 0.0 | inosine-5'-monophosphate dehydrogenase | 87.42 | 100.00 | ADE32434 |
| CLCPEIHJ_104 | 95732 | 97033 | Eno | 0.0 | enolase | 86.21 | 99.77 | ABP90468 |
| CLCPEIHJ_106 | 56431 | 54539 | gidA | 0.0 | tRNA uridine 5-carboxymethylaminomethyl modification enzyme | 86.05 | 98.90 | ABP91129 |
| CLCPEIHJ_52 | 2047 | 338 | PGM | 0.0 | phosphoglucomutase | 84.06 | 99.65 | ACH87041 |
| CLCPEIHJ_113 | 2073 | 1063 | pdh | 0.0 | pyruvate dehydrogenase | 83.09 | 99.70 | ABP91006 |
| CLCPEIHJ_37 | 30208 | 31569 | mnmE | 0.0 | central tRNA-modifying GTPase | 82.24 | 99.56 | ABP90420 |
| CLCPEIHJ_108 | 48441 | 46549 | PepO | 0.0 | endopeptidase | 80.19 | 100.00 | ABF32980 |
| CLCPEIHJ_104 | 81297 | 82187 | bglB | 8.49e-180 | putative phospho--glucosidase | 88.89 | 99.66 | AAK33487 |
| CLCPEIHJ_105 | 39594 | 40529 | SP_0676 | 1.75e-169 | transcription facot | 81.73 | 96.89 | AAK74821 |
| CLCPEIHJ_34 | 41622 | 40765 | metF | 4.05e-166 | methionine biosynthesis enzymes | 86.36 | 99.31 | AAK74739 |
| CLCPEIHJ_34 | 24442 | 23738 | covR | 1.16e-132 | responder protein | 85.53 | 100.00 | AAK71319 |
| CLCPEIHJ_114 | 28544 | 27873 | rr01 | 9.77e-126 | response regulator | 83.93 | 99.56 | CAB54566 |
| CLCPEIHJ_34 | 24442 | 23738 | walR | 4.90e-123 | DNA-binding response regulator | 82.13 | 100.00 | ANC99504 |
| CLCPEIHJ_9 | 7709 | 7023 | CovR | 6.33e-120 | serves to repress GAS virulence factor-encoding genes | 80.79 | 100.00 | ACE75886 |
| CLCPEIHJ_52 | 6001 | 6669 | CiaR | 8.50e-120 | two-component response regulator | 84.31 | 99.55 | AAK74935 |
| CLCPEIHJ_52 | 6001 | 6672 | ciaR | 8.36e-118 | two component system response regulator | 82.14 | 99.12 | AIK75708 |
| CLCPEIHJ_107 | 754 | 380 | SpxA2 | 8.99e-72 | transcriptional regulator | 91.20 | 94.70 | ERL21461 |
| CLCPEIHJ_37 | 18849 | 18448 | SpxA1 | 6.40e-68 | transcriptional regulator | 80.60 | 100.00 | ERL19273 |
| CLCPEIHJ_100 | 25606 | 25319 | spr0479 | 3.00e-49 | essential gene | 86.46 | 98.97 | AAK99283 |
| CLCPEIHJ_51 | 5689 | 5435 | spr1327 | 6.90e-45 | essential gene | 94.12 | 100.00 | AAL00131 |
| CLCPEIHJ_106 | 13841 | 14104 | spr0175 | 3.80e-42 | pathogenitcity related | 84.09 | 100.00 | AAK98979 |
| CLCPEIHJ_106 | 14668 | 14934 | spr0177 | 8.31e-34 | essential gene | 84.27 | 88.12 | AAK98981 |
| CLCPEIHJ_33 | 59295 | 58795 | RopE (M5005_Spy_1611) | 1.67e-76 | probable DNA-directed RNA polymerase subunit delta | 81.44 | 87.43 | AAK34603 |
| CLCPEIHJ_41 | 2286 | 4583 | PFL (B9H01_RS01125) | 0.0 | formate C-acetyltransferase | 82.94 | 98.08 | MYN69560 |
| CLCPEIHJ_108 | 33980 | 32961 | ilvC (SPD_0406) | 0.0 | ketol-acid reductoisomerase (NADP(+)) | 96.47 | 100.00 | ABJ55451 |
BLASTX v2.16.0 (Database: PHI base v4.16, May. 2024 release)
Plasmid
PlasmidFinder
| Query ID | Begin | End | Plasmid | Query / Template | Identity | Accession no. |
|---|---|---|---|---|---|---|
| No hit found | ||||||
PlasmidFinder v 2.1.6 (Database: plasmidfinder_db v 2.2.0 , Nov. 2024 release)
PlasmidHunter
| Query ID | Prediction | Chromosome | Plasmid |
|---|---|---|---|
| CLCPEIHJ_9 | 0.0 | 1.0 | 0.0 |
| CLCPEIHJ_14 | 1.0 | 0.0 | 1.0 |
| CLCPEIHJ_19 | 0.0 | 1.0 | 0.0 |
| CLCPEIHJ_28 | 0.0 | 1.0 | 0.0 |
| CLCPEIHJ_33 | 0.0 | 1.0 | 0.0 |
| CLCPEIHJ_34 | 0.0 | 1.0 | 0.0 |
| CLCPEIHJ_35 | 0.0 | 1.0 | 0.0 |
| CLCPEIHJ_36 | 0.0 | 1.0 | 0.0 |
| CLCPEIHJ_37 | 0.0 | 1.0 | 0.0 |
| CLCPEIHJ_38 | 0.0 | 1.0 | 0.0 |
| CLCPEIHJ_39 | 0.0 | 1.0 | 0.0 |
| CLCPEIHJ_40 | 0.0 | 1.0 | 0.0 |
| CLCPEIHJ_41 | 0.0 | 1.0 | 0.0 |
| CLCPEIHJ_42 | 0.0 | 1.0 | 0.0 |
| CLCPEIHJ_43 | 0.0 | 1.0 | 0.0 |
| CLCPEIHJ_44 | 1.0 | 0.0 | 1.0 |
| CLCPEIHJ_45 | 0.0 | 1.0 | 0.0 |
| CLCPEIHJ_46 | 0.0 | 1.0 | 0.0 |
| CLCPEIHJ_47 | 0.0 | 1.0 | 0.0 |
| CLCPEIHJ_50 | 0.0 | 1.0 | 0.0 |
| CLCPEIHJ_51 | 0.0 | 1.0 | 0.0 |
| CLCPEIHJ_52 | 0.0 | 1.0 | 0.0 |
| CLCPEIHJ_53 | 0.0 | 1.0 | 0.0 |
| CLCPEIHJ_54 | 1.0 | 0.0 | 1.0 |
| CLCPEIHJ_55 | 0.0 | 1.0 | 0.0 |
| CLCPEIHJ_56 | 1.0 | 0.0 | 1.0 |
| CLCPEIHJ_57 | 0.0 | 1.0 | 0.0 |
| CLCPEIHJ_58 | 1.0 | 0.0 | 1.0 |
| CLCPEIHJ_59 | 0.0 | 1.0 | 0.0 |
| CLCPEIHJ_60 | 1.0 | 0.0 | 1.0 |
| CLCPEIHJ_61 | 0.0 | 1.0 | 0.0 |
| CLCPEIHJ_62 | 0.0 | 1.0 | 0.0 |
| CLCPEIHJ_63 | 0.0 | 1.0 | 0.0 |
| CLCPEIHJ_64 | 0.0 | 1.0 | 0.0 |
| CLCPEIHJ_65 | 0.0 | 1.0 | 0.0 |
| CLCPEIHJ_66 | 0.0 | 1.0 | 0.0 |
| CLCPEIHJ_68 | 0.0 | 1.0 | 0.0 |
| CLCPEIHJ_69 | 1.0 | 0.0 | 1.0 |
| CLCPEIHJ_70 | 0.0 | 1.0 | 0.0 |
| CLCPEIHJ_71 | 0.0 | 1.0 | 0.0 |
| CLCPEIHJ_72 | 0.0 | 1.0 | 0.0 |
| CLCPEIHJ_73 | 0.0 | 1.0 | 0.0 |
| CLCPEIHJ_74 | 0.0 | 1.0 | 0.0 |
| CLCPEIHJ_75 | 0.0 | 1.0 | 0.0 |
| CLCPEIHJ_76 | 0.0 | 1.0 | 0.0 |
| CLCPEIHJ_79 | 0.0 | 1.0 | 0.0 |
| CLCPEIHJ_80 | 0.0 | 1.0 | 0.0 |
| CLCPEIHJ_83 | 0.0 | 1.0 | 0.0 |
| CLCPEIHJ_93 | 0.0 | 1.0 | 0.0 |
| CLCPEIHJ_97 | 0.0 | 1.0 | 0.0 |
| CLCPEIHJ_98 | 0.0 | 1.0 | 0.0 |
| CLCPEIHJ_99 | 0.0 | 1.0 | 0.0 |
| CLCPEIHJ_100 | 0.0 | 1.0 | 0.0 |
| CLCPEIHJ_101 | 0.0 | 1.0 | 0.0 |
| CLCPEIHJ_102 | 0.0 | 1.0 | 0.0 |
| CLCPEIHJ_103 | 0.0 | 1.0 | 0.0 |
| CLCPEIHJ_104 | 0.0 | 1.0 | 0.0 |
| CLCPEIHJ_105 | 0.0 | 1.0 | 0.0 |
| CLCPEIHJ_106 | 0.0 | 1.0 | 0.0 |
| CLCPEIHJ_107 | 0.0 | 1.0 | 0.0 |
| CLCPEIHJ_108 | 0.0 | 1.0 | 0.0 |
| CLCPEIHJ_109 | 0.0 | 1.0 | 0.0 |
| CLCPEIHJ_110 | 0.0 | 1.0 | 0.0 |
| CLCPEIHJ_112 | 0.0 | 1.0 | 0.0 |
| CLCPEIHJ_113 | 0.0 | 1.0 | 0.0 |
| CLCPEIHJ_114 | 0.0 | 1.0 | 0.0 |
| CLCPEIHJ_115 | 0.0 | 1.0 | 0.0 |
| CLCPEIHJ_116 | 0.0 | 1.0 | 0.0 |
| CLCPEIHJ_117 | 0.0 | 1.0 | 0.0 |
| CLCPEIHJ_119 | 0.0 | 1.0 | 0.0 |
| CLCPEIHJ_120 | 0.0 | 1.0 | 0.0 |
| CLCPEIHJ_122 | 0.0 | 1.0 | 0.0 |
PlasmidHunter v 1.4.5 (Database: May. 2024 release)
Prophage
Phigaro
| Query ID | Begin | End | Transposable | Taxonomy | pVOGs |
|---|---|---|---|---|---|
| No hit found | |||||
Phigaro v2.4.0 (Database: Jan. 2024 release)