Probiotic potential risk score
| ARGs | VFs | PGs | PPRS |
|---|---|---|---|
| 0 | 25 | 33 | 41.40 |
PPRS is classified as low-risk (≤4), medium-risk (4-6), and high-risk (≥6).
Antibiotic resistance genes
Comprehensive Antibiotic Resistance Database (CARD)
| Query ID | Begin | End | ARO name | ARO accession | CARD name | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
RGI v6.0.3 (Database: CARD Variants v4.0.2, Nov. 2023 release)
ResFinder
| Query ID | Begin | End | Resistance gene | Phenotype | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|
| No hit found | |||||||
ResFinder v4.6.0 (Database: resfinder_db, Aug. 2024 release)
AMRFinderPlus
| Query ID | Begin | End | Gene symbol | Sequence name | Method | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
AMRFinderPlus v4.0.3 (Database: Oct. 2024 release)
Virulence factors
Virulence Factor Database (VFDB)
| Query ID | qstart | qend | Gene name | e-value | VF name | VF category | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|---|
| CNGBMCEL_30 | 9594 | 10463 | rfbA | 0.0 | Capsule | Immune modulation | 100.00 | 100.00 | WP_011681286 |
| CNGBMCEL_30 | 9001 | 9594 | STER_RS06030 | 0.0 | Capsule | Immune modulation | 100.00 | 100.00 | WP_011226149 |
| CNGBMCEL_23 | 97808 | 99553 | STER_RS07045 | 0.0 | Capsule | Immune modulation | 100.00 | 100.00 | WP_011681434 |
| CNGBMCEL_23 | 96106 | 97806 | STER_RS07050 | 0.0 | Capsule | Immune modulation | 100.00 | 100.00 | WP_041827753 |
| CNGBMCEL_23 | 94886 | 96088 | STER_RS07055 | 0.0 | Capsule | Immune modulation | 100.00 | 100.00 | WP_011681436 |
| CNGBMCEL_23 | 94080 | 94886 | STER_RS07060 | 0.0 | Capsule | Immune modulation | 100.00 | 100.00 | WP_011681437 |
| CNGBMCEL_23 | 93139 | 94080 | STER_RS07065 | 0.0 | Capsule | Immune modulation | 100.00 | 100.00 | WP_011681438 |
| CNGBMCEL_23 | 91994 | 93142 | STER_RS07070 | 0.0 | Capsule | Immune modulation | 100.00 | 100.00 | WP_011681439 |
| CNGBMCEL_30 | 9001 | 9594 | STR_RS05880 | 0.0 | Capsule | Immune modulation | 99.83 | 100.00 | WP_011226149 |
| CNGBMCEL_23 | 96106 | 97806 | STR_RS06890 | 0.0 | Capsule | Immune modulation | 99.71 | 100.00 | WP_041827077 |
| CNGBMCEL_30 | 9001 | 9594 | STU_RS15260 | 0.0 | Capsule | Immune modulation | 99.66 | 100.00 | WP_011226149 |
| CNGBMCEL_23 | 91099 | 91875 | STER_RS07075 | 0.0 | Capsule | Immune modulation | 99.61 | 100.00 | WP_011681440 |
| CNGBMCEL_35 | 20680 | 21519 | cbpD | 0.0 | Autolysin | Exoenzyme | 99.52 | 100.00 | WP_011226733 |
| CNGBMCEL_27 | 54995 | 56653 | fbp54 | 0.0 | FBPs | Adherence | 99.52 | 100.00 | WP_011227179 |
| CNGBMCEL_23 | 94080 | 94886 | STR_RS06900 | 0.0 | Capsule | Immune modulation | 99.50 | 100.00 | WP_011227429 |
| CNGBMCEL_23 | 93139 | 94080 | STR_RS06905 | 0.0 | Capsule | Immune modulation | 99.47 | 100.00 | WP_011227430 |
| CNGBMCEL_23 | 94886 | 96088 | STR_RS06895 | 0.0 | Capsule | Immune modulation | 99.42 | 100.00 | WP_011227428 |
| CNGBMCEL_57 | 13719 | 14450 | STER_RS05315 | 0.0 | Capsule | Immune modulation | 99.32 | 100.00 | WP_011681176 |
| CNGBMCEL_23 | 91994 | 93142 | STR_RS06910 | 0.0 | Capsule | Immune modulation | 99.22 | 100.00 | WP_011227431 |
| CNGBMCEL_57 | 13719 | 14450 | STU_RS14645 | 0.0 | Capsule | Immune modulation | 98.77 | 100.00 | WP_011226048 |
| CNGBMCEL_57 | 13719 | 14450 | STR_RS05260 | 0.0 | Capsule | Immune modulation | 98.63 | 100.00 | WP_011227248 |
| CNGBMCEL_23 | 97808 | 99553 | STR_RS06885 | 0.0 | Capsule | Immune modulation | 98.22 | 100.00 | WP_011227426 |
| CNGBMCEL_23 | 90037 | 90753 | STER_RS07085 | 0.0 | Capsule | Immune modulation | 98.19 | 100.00 | WP_011681442 |
| CNGBMCEL_57 | 14451 | 15911 | STER_RS05320 | 0.0 | Capsule | Immune modulation | 97.67 | 100.00 | WP_011681177 |
| CNGBMCEL_30 | 44360 | 45121 | srtA | 0.0 | Sortase A | Exoenzyme | 97.64 | 100.00 | - |
| CNGBMCEL_23 | 85043 | 85894 | rfbD | 0.0 | Capsule | Immune modulation | 97.53 | 100.00 | WP_014621820 |
| CNGBMCEL_57 | 14451 | 15911 | STU_RS14650 | 0.0 | Capsule | Immune modulation | 96.51 | 100.21 | WP_011226049 |
| CNGBMCEL_57 | 12268 | 13008 | STER_RS05305 | 0.0 | Capsule | Immune modulation | 95.95 | 100.00 | WP_011681174 |
| CNGBMCEL_57 | 14451 | 15911 | STR_RS05265 | 0.0 | Capsule | Immune modulation | 95.69 | 100.21 | WP_041827043 |
| CNGBMCEL_57 | 12268 | 13008 | STU_RS14635 | 0.0 | Capsule | Immune modulation | 95.55 | 100.00 | WP_011226046 |
| CNGBMCEL_57 | 13018 | 13710 | STU_RS14640 | 0.0 | Capsule | Immune modulation | 95.53 | 100.00 | WP_011226047 |
| CNGBMCEL_57 | 12273 | 13008 | STR_RS05250 | 0.0 | Capsule | Immune modulation | 95.25 | 98.13 | WP_011227246 |
| CNGBMCEL_57 | 13018 | 13710 | STR_RS05255 | 0.0 | Capsule | Immune modulation | 95.24 | 100.00 | WP_011227247 |
| CNGBMCEL_57 | 10844 | 12211 | STU_RS14630 | 0.0 | Capsule | Immune modulation | 94.81 | 99.93 | WP_011226045 |
| CNGBMCEL_57 | 10846 | 12211 | STER_RS05300 | 0.0 | Capsule | Immune modulation | 94.44 | 99.71 | WP_011681173 |
| CNGBMCEL_106 | 43969 | 44747 | cshA | 0.0 | Cell surface hydrophobicity proteins | Adherence | 93.19 | 99.37 | - |
| CNGBMCEL_57 | 13018 | 13710 | STER_RS05310 | 0.0 | Capsule | Immune modulation | 92.78 | 100.00 | WP_011681175 |
| CNGBMCEL_64 | 94579 | 95882 | eno | 0.0 | Streptococcal enolase | Exoenzyme | 88.10 | 99.46 | WP_000022832 |
| CNGBMCEL_56 | 14314 | 15324 | plr/gapA | 0.0 | Streptococcal plasmin receptor/GAPDH | Adherence | 87.46 | 99.80 | WP_002986042 |
| CNGBMCEL_23 | 94080 | 94886 | SGO_RS05020 | 0.0 | Capsule | Immune modulation | 82.90 | 100.00 | WP_012000440 |
| CNGBMCEL_14 | 2307 | 3590 | tig/ropA | 0.0 | Trigger factor | Stress survival | 80.73 | 99.77 | WP_000107753 |
| CNGBMCEL_30 | 7526 | 8572 | rfbB | 0.0 | Capsule | Immune modulation | 80.61 | 100.00 | WP_009659423 |
| CNGBMCEL_57 | 1224 | 1807 | SPD_RS01775 | 1.66e-148 | Capsule | Immune modulation | 83.08 | 96.20 | WP_001819836 |
| CNGBMCEL_23 | 94886 | 95623 | SGO_RS05025 | 0.0 | Capsule | Immune modulation | 84.96 | 60.29 | WP_012000441 |
BLASTN v2.16.0 (Database: VFDB, Dec. 2024 release)
VirulenceFinder
| Query ID | Begin | End | Database | Virulence factor | Protein function | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
VirulenceFinder v2.0. 4 (Database: virulencefinder_db, Feb . 2024 release)
Pathogenic genes
PHI-base
| Query ID | qstart | qend | Gene name | e-value | Function | Identity | Coverage | Gene ID |
|---|---|---|---|---|---|---|---|---|
| CNGBMCEL_30 | 47808 | 48791 | ldh(Sp_1220) | 0.0 | L-lactate dehydrogenase | 94.82 | 100.00 | AAK75326 |
| CNGBMCEL_32 | 13767 | 12694 | MntE | 0.0 | manganese homeostasis | 94.41 | 99.72 | ABF32167 |
| CNGBMCEL_25 | 53037 | 54098 | SPD_0310 | 0.0 | UPF0371 protein SPD_0310 | 93.22 | 71.66 | ABJ54480 |
| CNGBMCEL_97 | 87908 | 90211 | pfl2(Sp_0459) | 0.0 | formate acetyltransferase | 93.10 | 99.22 | AAK74619 |
| CNGBMCEL_64 | 12351 | 13319 | spr0084 | 0.0 | pathogenitcity related | 92.57 | 98.48 | AAK98888 |
| CNGBMCEL_24 | 11398 | 9152 | metE | 0.0 | methionine biosynthesis enzymes | 91.99 | 100.00 | AAK74738 |
| CNGBMCEL_35 | 1888 | 890 | recA | 0.0 | DNA recombination and repair | 91.29 | 85.82 | AAL00560 |
| CNGBMCEL_80 | 15403 | 14432 | prsA2 | 0.0 | ribose-phosphate pyrophosphokinase | 90.12 | 100.00 | ABF36968 |
| CNGBMCEL_23 | 35854 | 37005 | potA | 0.0 | ABC transporter ATP-binding protein-spermidine/putrescine transport | 89.32 | 99.74 | AAL00050 |
| CNGBMCEL_23 | 71683 | 73671 | uvrB | 0.0 | excinuclease ABC, B subunit | 88.99 | 100.00 | AE014259_2 |
| CNGBMCEL_30 | 31610 | 29880 | ptsI | 0.0 | phosphoenolpyruvate-protein phosphotransferase | 88.22 | 100.00 | AAK34199 |
| CNGBMCEL_7 | 26845 | 25367 | IMPDH | 0.0 | inosine-5'-monophosphate dehydrogenase | 87.42 | 100.00 | ADE32434 |
| CNGBMCEL_64 | 94579 | 95880 | Eno | 0.0 | enolase | 86.21 | 99.77 | ABP90468 |
| CNGBMCEL_7 | 12109 | 10217 | gidA | 0.0 | tRNA uridine 5-carboxymethylaminomethyl modification enzyme | 85.74 | 98.90 | ABP91129 |
| CNGBMCEL_24 | 6227 | 7936 | PGM | 0.0 | phosphoglucomutase | 84.06 | 99.65 | ACH87041 |
| CNGBMCEL_79 | 51953 | 52963 | pdh | 0.0 | pyruvate dehydrogenase | 83.09 | 99.70 | ABP91006 |
| CNGBMCEL_27 | 30211 | 31572 | mnmE | 0.0 | central tRNA-modifying GTPase | 82.24 | 99.56 | ABP90420 |
| CNGBMCEL_28 | 5291 | 7183 | PepO | 0.0 | endopeptidase | 80.19 | 100.00 | ABF32980 |
| CNGBMCEL_64 | 80144 | 81034 | bglB | 1.12e-179 | putative phospho--glucosidase | 88.89 | 99.66 | AAK33487 |
| CNGBMCEL_54 | 39528 | 40463 | SP_0676 | 5.91e-169 | transcription facot | 81.41 | 96.89 | AAK74821 |
| CNGBMCEL_24 | 8960 | 8103 | metF | 1.40e-166 | methionine biosynthesis enzymes | 86.36 | 99.31 | AAK74739 |
| CNGBMCEL_106 | 72583 | 73287 | covR | 2.28e-132 | responder protein | 85.53 | 100.00 | AAK71319 |
| CNGBMCEL_25 | 28423 | 27752 | rr01 | 9.99e-125 | response regulator | 83.48 | 99.56 | CAB54566 |
| CNGBMCEL_106 | 72583 | 73287 | walR | 9.61e-123 | DNA-binding response regulator | 82.13 | 100.00 | ANC99504 |
| CNGBMCEL_18 | 16072 | 16758 | CovR | 1.27e-119 | serves to repress GAS virulence factor-encoding genes | 80.79 | 100.00 | ACE75886 |
| CNGBMCEL_24 | 2273 | 1605 | CiaR | 1.87e-119 | two-component response regulator | 84.31 | 99.55 | AAK74935 |
| CNGBMCEL_24 | 2273 | 1602 | ciaR | 1.84e-117 | two component system response regulator | 82.14 | 99.12 | AIK75708 |
| CNGBMCEL_35 | 614 | 240 | SpxA2 | 1.34e-71 | transcriptional regulator | 91.20 | 94.70 | ERL21461 |
| CNGBMCEL_27 | 18850 | 18449 | SpxA1 | 1.41e-67 | transcriptional regulator | 80.60 | 100.00 | ERL19273 |
| CNGBMCEL_52 | 25605 | 25318 | spr0479 | 6.95e-49 | essential gene | 85.42 | 98.97 | AAK99283 |
| CNGBMCEL_87 | 60807 | 61061 | spr1327 | 1.05e-45 | essential gene | 95.29 | 100.00 | AAL00131 |
| CNGBMCEL_62 | 23213 | 22950 | spr0175 | 1.49e-42 | pathogenitcity related | 84.09 | 100.00 | AAK98979 |
| CNGBMCEL_62 | 22386 | 22120 | spr0177 | 3.26e-34 | essential gene | 84.27 | 88.12 | AAK98981 |
| CNGBMCEL_14 | 3748 | 4248 | RopE (M5005_Spy_1611) | 1.67e-76 | probable DNA-directed RNA polymerase subunit delta | 81.44 | 87.43 | AAK34603 |
| CNGBMCEL_97 | 87908 | 90205 | PFL (B9H01_RS01125) | 0.0 | formate C-acetyltransferase | 83.07 | 98.08 | MYN69560 |
| CNGBMCEL_28 | 19749 | 20768 | ilvC (SPD_0406) | 0.0 | ketol-acid reductoisomerase (NADP(+)) | 96.47 | 100.00 | ABJ55451 |
BLASTX v2.16.0 (Database: PHI base v4.16, May. 2024 release)
Plasmid
PlasmidFinder
| Query ID | Begin | End | Plasmid | Query / Template | Identity | Accession no. |
|---|---|---|---|---|---|---|
| No hit found | ||||||
PlasmidFinder v 2.1.6 (Database: plasmidfinder_db v 2.2.0 , Nov. 2024 release)
PlasmidHunter
| Query ID | Prediction | Chromosome | Plasmid |
|---|---|---|---|
| CNGBMCEL_7 | 0.0 | 1.0 | 0.0 |
| CNGBMCEL_8 | 0.0 | 1.0 | 0.0 |
| CNGBMCEL_9 | 0.0 | 1.0 | 0.0 |
| CNGBMCEL_10 | 0.0 | 1.0 | 0.0 |
| CNGBMCEL_11 | 0.0 | 1.0 | 0.0 |
| CNGBMCEL_12 | 1.0 | 0.0 | 1.0 |
| CNGBMCEL_13 | 0.0 | 1.0 | 0.0 |
| CNGBMCEL_14 | 0.0 | 1.0 | 0.0 |
| CNGBMCEL_16 | 0.0 | 1.0 | 0.0 |
| CNGBMCEL_18 | 0.0 | 1.0 | 0.0 |
| CNGBMCEL_19 | 0.0 | 1.0 | 0.0 |
| CNGBMCEL_20 | 0.0 | 1.0 | 0.0 |
| CNGBMCEL_22 | 0.0 | 1.0 | 0.0 |
| CNGBMCEL_23 | 0.0 | 1.0 | 0.0 |
| CNGBMCEL_24 | 0.0 | 1.0 | 0.0 |
| CNGBMCEL_25 | 0.0 | 1.0 | 0.0 |
| CNGBMCEL_26 | 0.0 | 1.0 | 0.0 |
| CNGBMCEL_27 | 0.0 | 1.0 | 0.0 |
| CNGBMCEL_28 | 0.0 | 1.0 | 0.0 |
| CNGBMCEL_29 | 0.0 | 1.0 | 0.0 |
| CNGBMCEL_30 | 0.0 | 1.0 | 0.0 |
| CNGBMCEL_31 | 0.0 | 1.0 | 0.0 |
| CNGBMCEL_32 | 0.0 | 1.0 | 0.0 |
| CNGBMCEL_34 | 0.0 | 1.0 | 0.0 |
| CNGBMCEL_35 | 0.0 | 1.0 | 0.0 |
| CNGBMCEL_36 | 0.0 | 1.0 | 0.0 |
| CNGBMCEL_38 | 0.0 | 1.0 | 0.0 |
| CNGBMCEL_40 | 0.0 | 1.0 | 0.0 |
| CNGBMCEL_41 | 0.0 | 1.0 | 0.0 |
| CNGBMCEL_42 | 0.0 | 1.0 | 0.0 |
| CNGBMCEL_43 | 0.0 | 1.0 | 0.0 |
| CNGBMCEL_44 | 0.0 | 1.0 | 0.0 |
| CNGBMCEL_46 | 0.0 | 1.0 | 0.0 |
| CNGBMCEL_47 | 0.0 | 1.0 | 0.0 |
| CNGBMCEL_48 | 0.0 | 1.0 | 0.0 |
| CNGBMCEL_49 | 0.0 | 1.0 | 0.0 |
| CNGBMCEL_51 | 1.0 | 0.0 | 1.0 |
| CNGBMCEL_52 | 0.0 | 1.0 | 0.0 |
| CNGBMCEL_53 | 0.0 | 1.0 | 0.0 |
| CNGBMCEL_54 | 0.0 | 1.0 | 0.0 |
| CNGBMCEL_56 | 0.0 | 1.0 | 0.0 |
| CNGBMCEL_57 | 0.0 | 1.0 | 0.0 |
| CNGBMCEL_58 | 0.0 | 1.0 | 0.0 |
| CNGBMCEL_59 | 0.0 | 1.0 | 0.0 |
| CNGBMCEL_61 | 0.0 | 1.0 | 0.0 |
| CNGBMCEL_62 | 0.0 | 1.0 | 0.0 |
| CNGBMCEL_64 | 0.0 | 1.0 | 0.0 |
| CNGBMCEL_65 | 0.0 | 1.0 | 0.0 |
| CNGBMCEL_66 | 0.0 | 1.0 | 0.0 |
| CNGBMCEL_67 | 0.0 | 1.0 | 0.0 |
| CNGBMCEL_68 | 0.0 | 1.0 | 0.0 |
| CNGBMCEL_69 | 0.0 | 1.0 | 0.0 |
| CNGBMCEL_71 | 1.0 | 0.0 | 1.0 |
| CNGBMCEL_73 | 0.0 | 1.0 | 0.0 |
| CNGBMCEL_74 | 0.0 | 1.0 | 0.0 |
| CNGBMCEL_76 | 0.0 | 1.0 | 0.0 |
| CNGBMCEL_78 | 0.0 | 1.0 | 0.0 |
| CNGBMCEL_79 | 0.0 | 1.0 | 0.0 |
| CNGBMCEL_80 | 0.0 | 1.0 | 0.0 |
| CNGBMCEL_83 | 0.0 | 1.0 | 0.0 |
| CNGBMCEL_85 | 0.0 | 1.0 | 0.0 |
| CNGBMCEL_86 | 1.0 | 0.0 | 1.0 |
| CNGBMCEL_87 | 0.0 | 1.0 | 0.0 |
| CNGBMCEL_89 | 1.0 | 0.0 | 1.0 |
| CNGBMCEL_92 | 0.0 | 1.0 | 0.0 |
| CNGBMCEL_96 | 0.0 | 1.0 | 0.0 |
| CNGBMCEL_97 | 0.0 | 1.0 | 0.0 |
| CNGBMCEL_101 | 0.0 | 1.0 | 0.0 |
| CNGBMCEL_106 | 0.0 | 1.0 | 0.0 |
| CNGBMCEL_107 | 1.0 | 0.0 | 1.0 |
| CNGBMCEL_108 | 1.0 | 0.0 | 1.0 |
| CNGBMCEL_125 | 0.0 | 1.0 | 0.0 |
PlasmidHunter v 1.4.5 (Database: May. 2024 release)
Prophage
Phigaro
| Query ID | Begin | End | Transposable | Taxonomy | pVOGs |
|---|---|---|---|---|---|
| No hit found | |||||
Phigaro v2.4.0 (Database: Jan. 2024 release)