Probiotic potential risk score
| ARGs | VFs | PGs | PPRS |
|---|---|---|---|
| 0 | 23 | 32 | 39.41 |
PPRS is classified as low-risk (≤4), medium-risk (4-6), and high-risk (≥6).
Antibiotic resistance genes
Comprehensive Antibiotic Resistance Database (CARD)
| Query ID | Begin | End | ARO name | ARO accession | CARD name | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
RGI v6.0.3 (Database: CARD Variants v4.0.2, Nov. 2023 release)
ResFinder
| Query ID | Begin | End | Resistance gene | Phenotype | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|
| No hit found | |||||||
ResFinder v4.6.0 (Database: resfinder_db, Aug. 2024 release)
AMRFinderPlus
| Query ID | Begin | End | Gene symbol | Sequence name | Method | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
AMRFinderPlus v4.0.3 (Database: Oct. 2024 release)
Virulence factors
Virulence Factor Database (VFDB)
| Query ID | qstart | qend | Gene name | e-value | VF name | VF category | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|---|
| OFBKCMCC_4 | 26658 | 27917 | STER_RS07100 | 0.0 | Capsule | Immune modulation | 99.84 | 100.00 | WP_011681445 |
| OFBKCMCC_13 | 61155 | 61748 | STR_RS05880 | 0.0 | Capsule | Immune modulation | 99.66 | 100.00 | WP_011226149 |
| OFBKCMCC_13 | 61155 | 61748 | STER_RS06030 | 0.0 | Capsule | Immune modulation | 99.50 | 100.00 | WP_011226149 |
| OFBKCMCC_13 | 61155 | 61748 | STU_RS15260 | 0.0 | Capsule | Immune modulation | 99.50 | 100.00 | WP_011226149 |
| OFBKCMCC_4 | 24698 | 25666 | STER_RS07090 | 0.0 | Capsule | Immune modulation | 99.48 | 100.00 | WP_011681443 |
| OFBKCMCC_20 | 319 | 1977 | fbp54 | 0.0 | FBPs | Adherence | 99.46 | 100.00 | WP_011227179 |
| OFBKCMCC_4 | 25684 | 26661 | STER_RS07095 | 0.0 | Capsule | Immune modulation | 99.39 | 100.00 | WP_011681444 |
| OFBKCMCC_13 | 25628 | 26389 | srtA | 0.0 | Sortase A | Exoenzyme | 99.34 | 100.00 | - |
| OFBKCMCC_27 | 3902 | 4501 | STR_RS05245 | 0.0 | Capsule | Immune modulation | 99.33 | 100.00 | WP_196767671 |
| OFBKCMCC_27 | 1573 | 2304 | STR_RS05260 | 0.0 | Capsule | Immune modulation | 99.32 | 100.00 | WP_011227248 |
| OFBKCMCC_13 | 60286 | 61155 | rfbA | 0.0 | Capsule | Immune modulation | 99.31 | 100.00 | WP_011681286 |
| OFBKCMCC_27 | 1573 | 2304 | STU_RS14645 | 0.0 | Capsule | Immune modulation | 99.18 | 100.00 | WP_011226048 |
| OFBKCMCC_29 | 3256 | 4671 | STER_RS05250 | 0.0 | Capsule | Immune modulation | 99.01 | 100.00 | WP_011681165 |
| OFBKCMCC_27 | 1573 | 2304 | STER_RS05315 | 0.0 | Capsule | Immune modulation | 98.91 | 100.00 | WP_011681176 |
| OFBKCMCC_13 | 105801 | 106590 | cshA | 0.0 | Cell surface hydrophobicity proteins | Adherence | 98.74 | 99.87 | - |
| OFBKCMCC_16 | 50777 | 51745 | cbpD | 0.0 | Autolysin | Exoenzyme | 98.66 | 100.00 | WP_082302295 |
| OFBKCMCC_27 | 118 | 1572 | STR_RS05265 | 0.0 | Capsule | Immune modulation | 98.49 | 100.00 | WP_041827043 |
| OFBKCMCC_27 | 4666 | 5625 | STR_RS05240 | 0.0 | Capsule | Immune modulation | 98.23 | 100.00 | WP_041827042 |
| OFBKCMCC_27 | 118 | 1572 | STU_RS14650 | 0.0 | Capsule | Immune modulation | 98.21 | 100.00 | WP_011226049 |
| OFBKCMCC_4 | 22865 | 23635 | STER_RS07075 | 0.0 | Capsule | Immune modulation | 97.92 | 99.23 | WP_011681440 |
| OFBKCMCC_4 | 23981 | 24696 | STER_RS07085 | 0.0 | Capsule | Immune modulation | 97.91 | 99.86 | WP_011681442 |
| OFBKCMCC_27 | 2313 | 3005 | STR_RS05255 | 0.0 | Capsule | Immune modulation | 97.69 | 100.00 | WP_011227247 |
| OFBKCMCC_27 | 2313 | 3005 | STU_RS14640 | 0.0 | Capsule | Immune modulation | 97.69 | 100.00 | WP_011226047 |
| OFBKCMCC_27 | 3015 | 3750 | STER_RS05305 | 0.0 | Capsule | Immune modulation | 97.55 | 99.33 | WP_011681174 |
| OFBKCMCC_27 | 118 | 1572 | STER_RS05320 | 0.0 | Capsule | Immune modulation | 97.33 | 99.79 | WP_011681177 |
| OFBKCMCC_27 | 3015 | 3764 | STR_RS05250 | 0.0 | Capsule | Immune modulation | 96.93 | 100.00 | WP_011227246 |
| OFBKCMCC_27 | 3015 | 3750 | STU_RS14635 | 0.0 | Capsule | Immune modulation | 96.88 | 99.33 | WP_011226046 |
| OFBKCMCC_4 | 28036 | 28887 | rfbD | 0.0 | Capsule | Immune modulation | 96.36 | 100.00 | WP_014621820 |
| OFBKCMCC_27 | 2313 | 3005 | STER_RS05310 | 0.0 | Capsule | Immune modulation | 90.48 | 100.00 | WP_011681175 |
| OFBKCMCC_24 | 108360 | 109663 | eno | 0.0 | Streptococcal enolase | Exoenzyme | 88.17 | 99.54 | WP_000022832 |
| OFBKCMCC_95 | 14309 | 15319 | plr/gapA | 0.0 | Streptococcal plasmin receptor/GAPDH | Adherence | 86.82 | 99.51 | WP_002986042 |
| OFBKCMCC_13 | 62177 | 63223 | rfbB | 0.0 | Capsule | Immune modulation | 80.71 | 100.00 | WP_009659423 |
| OFBKCMCC_75 | 2339 | 3622 | tig/ropA | 0.0 | Trigger factor | Stress survival | 80.65 | 99.77 | WP_000107753 |
BLASTN v2.16.0 (Database: VFDB, Dec. 2024 release)
VirulenceFinder
| Query ID | Begin | End | Database | Virulence factor | Protein function | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
VirulenceFinder v2.0. 4 (Database: virulencefinder_db, Feb . 2024 release)
Pathogenic genes
PHI-base
| Query ID | qstart | qend | Gene name | e-value | Function | Identity | Coverage | Gene ID |
|---|---|---|---|---|---|---|---|---|
| OFBKCMCC_13 | 22941 | 21958 | ldh(Sp_1220) | 0.0 | L-lactate dehydrogenase | 94.82 | 100.00 | AAK75326 |
| OFBKCMCC_24 | 209431 | 210504 | MntE | 0.0 | manganese homeostasis | 94.41 | 99.72 | ABF32167 |
| OFBKCMCC_24 | 24819 | 25787 | spr0084 | 0.0 | pathogenitcity related | 93.19 | 98.48 | AAK98888 |
| OFBKCMCC_12 | 136979 | 139282 | pfl2(Sp_0459) | 0.0 | formate acetyltransferase | 93.10 | 99.22 | AAK74619 |
| OFBKCMCC_71 | 60994 | 59513 | SPD_0310 | 0.0 | UPF0371 protein SPD_0310 | 92.11 | 100.00 | ABJ54480 |
| OFBKCMCC_79 | 5577 | 7823 | metE | 0.0 | methionine biosynthesis enzymes | 91.86 | 100.00 | AAK74738 |
| OFBKCMCC_74 | 3311 | 4282 | prsA2 | 0.0 | ribose-phosphate pyrophosphokinase | 90.12 | 100.00 | ABF36968 |
| OFBKCMCC_12 | 23222 | 22071 | potA | 0.0 | ABC transporter ATP-binding protein-spermidine/putrescine transport | 89.06 | 99.74 | AAL00050 |
| OFBKCMCC_4 | 42135 | 40147 | uvrB | 0.0 | excinuclease ABC, B subunit | 88.99 | 100.00 | AE014259_2 |
| OFBKCMCC_13 | 39136 | 40866 | ptsI | 0.0 | phosphoenolpyruvate-protein phosphotransferase | 87.69 | 100.00 | AAK34199 |
| OFBKCMCC_64 | 27041 | 28519 | IMPDH | 0.0 | inosine-5'-monophosphate dehydrogenase | 87.63 | 100.00 | ADE32434 |
| OFBKCMCC_24 | 108360 | 109661 | Eno | 0.0 | enolase | 86.21 | 99.77 | ABP90468 |
| OFBKCMCC_64 | 41776 | 43668 | gidA | 0.0 | tRNA uridine 5-carboxymethylaminomethyl modification enzyme | 85.89 | 98.90 | ABP91129 |
| OFBKCMCC_22 | 19862 | 20968 | recA | 0.0 | DNA recombination and repair | 84.91 | 95.36 | AAL00560 |
| OFBKCMCC_79 | 10748 | 9039 | PGM | 0.0 | phosphoglucomutase | 83.71 | 99.65 | ACH87041 |
| OFBKCMCC_46 | 55002 | 53992 | pdh | 0.0 | pyruvate dehydrogenase | 83.38 | 99.70 | ABP91006 |
| OFBKCMCC_84 | 24570 | 23209 | mnmE | 0.0 | central tRNA-modifying GTPase | 82.24 | 99.56 | ABP90420 |
| OFBKCMCC_46 | 4722 | 6614 | PepO | 0.0 | endopeptidase | 80.03 | 100.00 | ABF32980 |
| OFBKCMCC_24 | 93929 | 94819 | bglB | 1.60e-179 | putative phospho--glucosidase | 88.89 | 99.66 | AAK33487 |
| OFBKCMCC_72 | 41114 | 42052 | SP_0676 | 2.01e-169 | transcription facot | 81.47 | 97.20 | AAK74821 |
| OFBKCMCC_79 | 8015 | 8872 | metF | 7.63e-167 | methionine biosynthesis enzymes | 86.36 | 99.31 | AAK74739 |
| OFBKCMCC_13 | 134306 | 135010 | covR | 2.99e-131 | responder protein | 84.68 | 100.00 | AAK71319 |
| OFBKCMCC_71 | 79957 | 80628 | rr01 | 1.11e-126 | response regulator | 84.82 | 99.56 | CAB54566 |
| OFBKCMCC_79 | 14701 | 15369 | CiaR | 1.53e-123 | two-component response regulator | 86.55 | 99.55 | AAK74935 |
| OFBKCMCC_79 | 14701 | 15372 | ciaR | 1.45e-121 | two component system response regulator | 84.38 | 99.12 | AIK75708 |
| OFBKCMCC_13 | 134306 | 135010 | walR | 2.15e-121 | DNA-binding response regulator | 80.85 | 100.00 | ANC99504 |
| OFBKCMCC_6 | 83722 | 84408 | CovR | 4.93e-119 | serves to repress GAS virulence factor-encoding genes | 80.79 | 100.00 | ACE75886 |
| OFBKCMCC_22 | 21152 | 21526 | SpxA2 | 1.35e-71 | transcriptional regulator | 91.20 | 94.70 | ERL21461 |
| OFBKCMCC_73 | 25449 | 25162 | spr0479 | 3.33e-49 | essential gene | 86.46 | 98.97 | AAK99283 |
| OFBKCMCC_16 | 9898 | 9644 | spr1327 | 1.63e-45 | essential gene | 95.29 | 100.00 | AAL00131 |
| OFBKCMCC_64 | 75382 | 75119 | spr0175 | 5.30e-42 | pathogenitcity related | 84.09 | 100.00 | AAK98979 |
| OFBKCMCC_64 | 74555 | 74289 | spr0177 | 9.35e-34 | essential gene | 84.27 | 88.12 | AAK98981 |
| OFBKCMCC_75 | 3780 | 4280 | RopE (M5005_Spy_1611) | 1.76e-76 | probable DNA-directed RNA polymerase subunit delta | 81.44 | 87.43 | AAK34603 |
| OFBKCMCC_12 | 136979 | 139276 | PFL (B9H01_RS01125) | 0.0 | formate C-acetyltransferase | 83.07 | 98.08 | MYN69560 |
| OFBKCMCC_46 | 19137 | 20156 | ilvC (SPD_0406) | 0.0 | ketol-acid reductoisomerase (NADP(+)) | 96.47 | 100.00 | ABJ55451 |
BLASTX v2.16.0 (Database: PHI base v4.16, May. 2024 release)
Plasmid
PlasmidFinder
| Query ID | Begin | End | Plasmid | Query / Template | Identity | Accession no. |
|---|---|---|---|---|---|---|
| No hit found | ||||||
PlasmidFinder v 2.1.6 (Database: plasmidfinder_db v 2.2.0 , Nov. 2024 release)
PlasmidHunter
| Query ID | Prediction | Chromosome | Plasmid |
|---|---|---|---|
| OFBKCMCC_4 | 0.0 | 1.0 | 0.0 |
| OFBKCMCC_5 | 0.0 | 1.0 | 0.0 |
| OFBKCMCC_6 | 0.0 | 1.0 | 0.0 |
| OFBKCMCC_7 | 0.0 | 1.0 | 0.0 |
| OFBKCMCC_8 | 0.0 | 1.0 | 0.0 |
| OFBKCMCC_9 | 0.0 | 1.0 | 0.0 |
| OFBKCMCC_10 | 0.0 | 1.0 | 0.0 |
| OFBKCMCC_11 | 0.0 | 1.0 | 0.0 |
| OFBKCMCC_12 | 0.0 | 1.0 | 0.0 |
| OFBKCMCC_13 | 0.0 | 1.0 | 0.0 |
| OFBKCMCC_14 | 0.0 | 1.0 | 0.0 |
| OFBKCMCC_15 | 0.0 | 1.0 | 0.0 |
| OFBKCMCC_16 | 0.0 | 1.0 | 0.0 |
| OFBKCMCC_17 | 0.0 | 1.0 | 0.0 |
| OFBKCMCC_19 | 1.0 | 0.0 | 1.0 |
| OFBKCMCC_20 | 0.0 | 1.0 | 0.0 |
| OFBKCMCC_21 | 0.0 | 1.0 | 0.0 |
| OFBKCMCC_22 | 0.0 | 1.0 | 0.0 |
| OFBKCMCC_23 | 0.0 | 1.0 | 0.0 |
| OFBKCMCC_24 | 0.0 | 1.0 | 0.0 |
| OFBKCMCC_25 | 0.0 | 1.0 | 0.0 |
| OFBKCMCC_26 | 0.0 | 1.0 | 0.0 |
| OFBKCMCC_27 | 0.0 | 1.0 | 0.0 |
| OFBKCMCC_28 | 0.0 | 1.0 | 0.0 |
| OFBKCMCC_29 | 1.0 | 0.0 | 1.0 |
| OFBKCMCC_30 | 0.0 | 1.0 | 0.0 |
| OFBKCMCC_32 | 0.0 | 1.0 | 0.0 |
| OFBKCMCC_33 | 1.0 | 0.0 | 1.0 |
| OFBKCMCC_34 | 1.0 | 0.0 | 1.0 |
| OFBKCMCC_35 | 0.0 | 1.0 | 0.0 |
| OFBKCMCC_36 | 1.0 | 0.0 | 1.0 |
| OFBKCMCC_37 | 1.0 | 0.0 | 1.0 |
| OFBKCMCC_40 | 0.0 | 1.0 | 0.0 |
| OFBKCMCC_41 | 0.0 | 1.0 | 0.0 |
| OFBKCMCC_46 | 0.0 | 1.0 | 0.0 |
| OFBKCMCC_56 | 0.0 | 1.0 | 0.0 |
| OFBKCMCC_62 | 0.0 | 1.0 | 0.0 |
| OFBKCMCC_64 | 0.0 | 1.0 | 0.0 |
| OFBKCMCC_71 | 0.0 | 1.0 | 0.0 |
| OFBKCMCC_72 | 0.0 | 1.0 | 0.0 |
| OFBKCMCC_73 | 0.0 | 1.0 | 0.0 |
| OFBKCMCC_74 | 0.0 | 1.0 | 0.0 |
| OFBKCMCC_75 | 0.0 | 1.0 | 0.0 |
| OFBKCMCC_76 | 0.0 | 1.0 | 0.0 |
| OFBKCMCC_77 | 0.0 | 1.0 | 0.0 |
| OFBKCMCC_78 | 0.0 | 1.0 | 0.0 |
| OFBKCMCC_79 | 0.0 | 1.0 | 0.0 |
| OFBKCMCC_80 | 0.0 | 1.0 | 0.0 |
| OFBKCMCC_84 | 0.0 | 1.0 | 0.0 |
| OFBKCMCC_93 | 0.0 | 1.0 | 0.0 |
| OFBKCMCC_95 | 0.0 | 1.0 | 0.0 |
PlasmidHunter v 1.4.5 (Database: May. 2024 release)
Prophage
Phigaro
| Query ID | Begin | End | Transposable | Taxonomy | pVOGs |
|---|---|---|---|---|---|
| No hit found | |||||
Phigaro v2.4.0 (Database: Jan. 2024 release)