Probiotic potential risk score
| ARGs | VFs | PGs | PPRS |
|---|---|---|---|
| 0 | 25 | 33 | 41.40 |
PPRS is classified as low-risk (≤4), medium-risk (4-6), and high-risk (≥6).
Antibiotic resistance genes
Comprehensive Antibiotic Resistance Database (CARD)
| Query ID | Begin | End | ARO name | ARO accession | CARD name | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
RGI v6.0.3 (Database: CARD Variants v4.0.2, Nov. 2023 release)
ResFinder
| Query ID | Begin | End | Resistance gene | Phenotype | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|
| No hit found | |||||||
ResFinder v4.6.0 (Database: resfinder_db, Aug. 2024 release)
AMRFinderPlus
| Query ID | Begin | End | Gene symbol | Sequence name | Method | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
AMRFinderPlus v4.0.3 (Database: Oct. 2024 release)
Virulence factors
Virulence Factor Database (VFDB)
| Query ID | qstart | qend | Gene name | e-value | VF name | VF category | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|---|
| IJJCEOHG_21 | 10374 | 11243 | rfbA | 0.0 | Capsule | Immune modulation | 100.00 | 100.00 | WP_011681286 |
| IJJCEOHG_21 | 9781 | 10374 | STER_RS06030 | 0.0 | Capsule | Immune modulation | 100.00 | 100.00 | WP_011226149 |
| IJJCEOHG_24 | 23196 | 24002 | STER_RS07060 | 0.0 | Capsule | Immune modulation | 100.00 | 100.00 | WP_011681437 |
| IJJCEOHG_21 | 9781 | 10374 | STR_RS05880 | 0.0 | Capsule | Immune modulation | 99.83 | 100.00 | WP_011226149 |
| IJJCEOHG_20 | 59379 | 60110 | STER_RS05315 | 0.0 | Capsule | Immune modulation | 99.73 | 100.00 | WP_011681176 |
| IJJCEOHG_24 | 18487 | 20232 | STR_RS06885 | 0.0 | Capsule | Immune modulation | 99.71 | 100.00 | WP_011227426 |
| IJJCEOHG_24 | 24002 | 24943 | STR_RS06905 | 0.0 | Capsule | Immune modulation | 99.68 | 100.00 | WP_011227430 |
| IJJCEOHG_21 | 9781 | 10374 | STU_RS15260 | 0.0 | Capsule | Immune modulation | 99.66 | 100.00 | WP_011226149 |
| IJJCEOHG_24 | 20336 | 21976 | STER_RS07050 | 0.0 | Capsule | Immune modulation | 99.63 | 96.47 | WP_041827753 |
| IJJCEOHG_19 | 13701 | 15359 | fbp54 | 0.0 | FBPs | Adherence | 99.58 | 100.00 | WP_011227179 |
| IJJCEOHG_24 | 24002 | 24943 | STER_RS07065 | 0.0 | Capsule | Immune modulation | 99.58 | 100.00 | WP_011681438 |
| IJJCEOHG_1 | 21027 | 21866 | cbpD | 0.0 | Autolysin | Exoenzyme | 99.52 | 100.00 | WP_011226733 |
| IJJCEOHG_24 | 21994 | 23196 | STER_RS07055 | 0.0 | Capsule | Immune modulation | 99.50 | 100.00 | WP_011681436 |
| IJJCEOHG_24 | 23196 | 24002 | STR_RS06900 | 0.0 | Capsule | Immune modulation | 99.50 | 100.00 | WP_011227429 |
| IJJCEOHG_24 | 20336 | 21976 | STR_RS06890 | 0.0 | Capsule | Immune modulation | 99.45 | 96.47 | WP_041827077 |
| IJJCEOHG_24 | 21994 | 23196 | STR_RS06895 | 0.0 | Capsule | Immune modulation | 99.42 | 100.00 | WP_011227428 |
| IJJCEOHG_24 | 28749 | 30023 | STU_RS16265 | 0.0 | Capsule | Immune modulation | 98.98 | 100.00 | WP_011226331 |
| IJJCEOHG_24 | 27787 | 28749 | STU_RS16260 | 0.0 | Capsule | Immune modulation | 98.86 | 95.25 | WP_011226330 |
| IJJCEOHG_20 | 57928 | 58668 | STER_RS05305 | 0.0 | Capsule | Immune modulation | 98.52 | 100.00 | WP_011681174 |
| IJJCEOHG_20 | 57928 | 58668 | STU_RS14635 | 0.0 | Capsule | Immune modulation | 98.38 | 100.00 | WP_011226046 |
| IJJCEOHG_24 | 18487 | 20232 | STER_RS07045 | 0.0 | Capsule | Immune modulation | 98.17 | 100.00 | WP_011681434 |
| IJJCEOHG_24 | 31126 | 31977 | rfbD | 0.0 | Capsule | Immune modulation | 98.12 | 100.00 | WP_014621820 |
| IJJCEOHG_20 | 57933 | 58668 | STR_RS05250 | 0.0 | Capsule | Immune modulation | 98.10 | 98.13 | WP_011227246 |
| IJJCEOHG_20 | 59379 | 60110 | STR_RS05260 | 0.0 | Capsule | Immune modulation | 97.95 | 100.00 | WP_011227248 |
| IJJCEOHG_20 | 59379 | 60110 | STU_RS14645 | 0.0 | Capsule | Immune modulation | 97.81 | 100.00 | WP_011226048 |
| IJJCEOHG_21 | 45145 | 45906 | srtA | 0.0 | Sortase A | Exoenzyme | 97.77 | 100.00 | - |
| IJJCEOHG_20 | 60111 | 61571 | STER_RS05320 | 0.0 | Capsule | Immune modulation | 97.67 | 100.00 | WP_011681177 |
| IJJCEOHG_20 | 60111 | 61571 | STU_RS14650 | 0.0 | Capsule | Immune modulation | 96.51 | 100.21 | WP_011226049 |
| IJJCEOHG_20 | 60111 | 61571 | STR_RS05265 | 0.0 | Capsule | Immune modulation | 95.69 | 100.21 | WP_041827043 |
| IJJCEOHG_20 | 56507 | 57872 | STER_RS05300 | 0.0 | Capsule | Immune modulation | 95.39 | 99.85 | WP_011681173 |
| IJJCEOHG_20 | 56505 | 57872 | STU_RS14630 | 0.0 | Capsule | Immune modulation | 94.37 | 100.00 | WP_011226045 |
| IJJCEOHG_20 | 125993 | 126771 | cshA | 0.0 | Cell surface hydrophobicity proteins | Adherence | 93.19 | 99.37 | - |
| IJJCEOHG_24 | 24940 | 26085 | STR_RS06910 | 0.0 | Capsule | Immune modulation | 93.02 | 99.74 | WP_011227431 |
| IJJCEOHG_24 | 24940 | 26085 | STER_RS07070 | 0.0 | Capsule | Immune modulation | 92.76 | 99.74 | WP_011681439 |
| IJJCEOHG_20 | 58678 | 59370 | STER_RS05310 | 0.0 | Capsule | Immune modulation | 92.50 | 100.00 | WP_011681175 |
| IJJCEOHG_9 | 95232 | 96535 | eno | 0.0 | Streptococcal enolase | Exoenzyme | 88.10 | 99.46 | WP_000022832 |
| IJJCEOHG_20 | 58678 | 59370 | STU_RS14640 | 0.0 | Capsule | Immune modulation | 87.88 | 100.00 | WP_011226047 |
| IJJCEOHG_20 | 58678 | 59370 | STR_RS05255 | 0.0 | Capsule | Immune modulation | 87.59 | 100.00 | WP_011227247 |
| IJJCEOHG_28 | 916 | 1926 | plr/gapA | 0.0 | Streptococcal plasmin receptor/GAPDH | Adherence | 87.46 | 99.80 | WP_002986042 |
| IJJCEOHG_24 | 23196 | 24002 | SGO_RS05020 | 0.0 | Capsule | Immune modulation | 82.90 | 100.00 | WP_012000440 |
| IJJCEOHG_4 | 6935 | 8218 | tig/ropA | 0.0 | Trigger factor | Stress survival | 80.73 | 99.77 | WP_000107753 |
| IJJCEOHG_21 | 8306 | 9352 | rfbB | 0.0 | Capsule | Immune modulation | 80.61 | 100.00 | WP_009659423 |
| IJJCEOHG_20 | 46974 | 47557 | SPD_RS01775 | 1.01e-147 | Capsule | Immune modulation | 83.11 | 96.04 | WP_001819836 |
| IJJCEOHG_24 | 22459 | 23196 | SGO_RS05025 | 0.0 | Capsule | Immune modulation | 84.96 | 60.29 | WP_012000441 |
BLASTN v2.16.0 (Database: VFDB, Dec. 2024 release)
VirulenceFinder
| Query ID | Begin | End | Database | Virulence factor | Protein function | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
VirulenceFinder v2.0. 4 (Database: virulencefinder_db, Feb . 2024 release)
Pathogenic genes
PHI-base
| Query ID | qstart | qend | Gene name | e-value | Function | Identity | Coverage | Gene ID |
|---|---|---|---|---|---|---|---|---|
| IJJCEOHG_12 | 25547 | 26620 | MntE | 0.0 | manganese homeostasis | 94.41 | 99.72 | ABF32167 |
| IJJCEOHG_21 | 48593 | 49576 | ldh(Sp_1220) | 0.0 | L-lactate dehydrogenase | 94.21 | 100.00 | AAK75326 |
| IJJCEOHG_9 | 12987 | 13955 | spr0084 | 0.0 | pathogenitcity related | 93.19 | 98.48 | AAK98888 |
| IJJCEOHG_26 | 67557 | 69860 | pfl2(Sp_0459) | 0.0 | formate acetyltransferase | 92.97 | 99.22 | AAK74619 |
| IJJCEOHG_22 | 57393 | 58874 | SPD_0310 | 0.0 | UPF0371 protein SPD_0310 | 92.71 | 100.00 | ABJ54480 |
| IJJCEOHG_13 | 6897 | 9143 | metE | 0.0 | methionine biosynthesis enzymes | 91.99 | 100.00 | AAK74738 |
| IJJCEOHG_1 | 40658 | 41656 | recA | 0.0 | DNA recombination and repair | 91.29 | 85.82 | AAL00560 |
| IJJCEOHG_1 | 4543 | 5514 | prsA2 | 0.0 | ribose-phosphate pyrophosphokinase | 90.12 | 100.00 | ABF36968 |
| IJJCEOHG_25 | 24170 | 23019 | potA | 0.0 | ABC transporter ATP-binding protein-spermidine/putrescine transport | 89.32 | 99.74 | AAL00050 |
| IJJCEOHG_24 | 45153 | 43165 | uvrB | 0.0 | excinuclease ABC, B subunit | 88.84 | 100.00 | AE014259_2 |
| IJJCEOHG_21 | 32394 | 30664 | ptsI | 0.0 | phosphoenolpyruvate-protein phosphotransferase | 88.04 | 100.00 | AAK34199 |
| IJJCEOHG_32 | 73857 | 72379 | IMPDH | 0.0 | inosine-5'-monophosphate dehydrogenase | 87.63 | 100.00 | ADE32434 |
| IJJCEOHG_9 | 95232 | 96533 | Eno | 0.0 | enolase | 86.21 | 99.77 | ABP90468 |
| IJJCEOHG_32 | 59119 | 57227 | gidA | 0.0 | tRNA uridine 5-carboxymethylaminomethyl modification enzyme | 85.74 | 98.90 | ABP91129 |
| IJJCEOHG_13 | 12068 | 10359 | PGM | 0.0 | phosphoglucomutase | 84.06 | 99.65 | ACH87041 |
| IJJCEOHG_29 | 22769 | 23779 | pdh | 0.0 | pyruvate dehydrogenase | 82.79 | 99.70 | ABP91006 |
| IJJCEOHG_19 | 40336 | 38975 | mnmE | 0.0 | central tRNA-modifying GTPase | 82.24 | 99.56 | ABP90420 |
| IJJCEOHG_29 | 73087 | 71195 | PepO | 0.0 | endopeptidase | 80.19 | 100.00 | ABF32980 |
| IJJCEOHG_9 | 80797 | 81687 | bglB | 1.21e-179 | putative phospho--glucosidase | 88.89 | 99.66 | AAK33487 |
| IJJCEOHG_18 | 12374 | 11439 | SP_0676 | 2.09e-169 | transcription facot | 81.73 | 96.89 | AAK74821 |
| IJJCEOHG_13 | 9335 | 10192 | metF | 1.68e-166 | methionine biosynthesis enzymes | 86.36 | 99.31 | AAK74739 |
| IJJCEOHG_20 | 98361 | 97657 | covR | 4.04e-132 | responder protein | 85.53 | 100.00 | AAK71319 |
| IJJCEOHG_22 | 29289 | 28618 | rr01 | 1.15e-125 | response regulator | 83.93 | 99.56 | CAB54566 |
| IJJCEOHG_20 | 98361 | 97657 | walR | 1.70e-122 | DNA-binding response regulator | 82.13 | 100.00 | ANC99504 |
| IJJCEOHG_13 | 16022 | 16690 | CiaR | 2.24e-119 | two-component response regulator | 84.31 | 99.55 | AAK74935 |
| IJJCEOHG_4 | 159833 | 160519 | CovR | 9.11e-119 | serves to repress GAS virulence factor-encoding genes | 80.79 | 100.00 | ACE75886 |
| IJJCEOHG_13 | 16022 | 16693 | ciaR | 2.20e-117 | two component system response regulator | 82.14 | 99.12 | AIK75708 |
| IJJCEOHG_1 | 41932 | 42306 | SpxA2 | 2.68e-71 | transcriptional regulator | 91.20 | 94.70 | ERL21461 |
| IJJCEOHG_19 | 51801 | 52202 | SpxA1 | 1.34e-67 | transcriptional regulator | 80.60 | 100.00 | ERL19273 |
| IJJCEOHG_5 | 14773 | 15060 | spr0479 | 3.11e-49 | essential gene | 86.46 | 98.97 | AAK99283 |
| IJJCEOHG_7 | 100484 | 100738 | spr1327 | 1.32e-44 | essential gene | 94.12 | 100.00 | AAL00131 |
| IJJCEOHG_32 | 14529 | 14792 | spr0175 | 3.91e-42 | pathogenitcity related | 84.09 | 100.00 | AAK98979 |
| IJJCEOHG_32 | 15356 | 15622 | spr0177 | 8.54e-34 | essential gene | 84.27 | 88.12 | AAK98981 |
| IJJCEOHG_4 | 8376 | 8876 | RopE (M5005_Spy_1611) | 4.46e-76 | probable DNA-directed RNA polymerase subunit delta | 81.44 | 87.43 | AAK34603 |
| IJJCEOHG_26 | 67557 | 69854 | PFL (B9H01_RS01125) | 0.0 | formate C-acetyltransferase | 82.94 | 98.08 | MYN69560 |
| IJJCEOHG_29 | 58633 | 57614 | ilvC (SPD_0406) | 0.0 | ketol-acid reductoisomerase (NADP(+)) | 96.47 | 100.00 | ABJ55451 |
BLASTX v2.16.0 (Database: PHI base v4.16, May. 2024 release)
Plasmid
PlasmidFinder
| Query ID | Begin | End | Plasmid | Query / Template | Identity | Accession no. |
|---|---|---|---|---|---|---|
| No hit found | ||||||
PlasmidFinder v 2.1.6 (Database: plasmidfinder_db v 2.2.0 , Nov. 2024 release)
PlasmidHunter
| Query ID | Prediction | Chromosome | Plasmid |
|---|---|---|---|
| IJJCEOHG_1 | 0.0 | 1.0 | 0.0 |
| IJJCEOHG_2 | 0.0 | 1.0 | 0.0 |
| IJJCEOHG_3 | 0.0 | 1.0 | 0.0 |
| IJJCEOHG_4 | 0.0 | 1.0 | 0.0 |
| IJJCEOHG_5 | 0.0 | 1.0 | 0.0 |
| IJJCEOHG_6 | 0.0 | 1.0 | 0.0 |
| IJJCEOHG_7 | 0.0 | 1.0 | 0.0 |
| IJJCEOHG_8 | 0.0 | 1.0 | 0.0 |
| IJJCEOHG_9 | 0.0 | 1.0 | 0.0 |
| IJJCEOHG_10 | 0.0 | 1.0 | 0.0 |
| IJJCEOHG_11 | 0.0 | 1.0 | 0.0 |
| IJJCEOHG_12 | 0.0 | 1.0 | 0.0 |
| IJJCEOHG_13 | 0.0 | 1.0 | 0.0 |
| IJJCEOHG_14 | 0.0 | 1.0 | 0.0 |
| IJJCEOHG_15 | 0.0 | 1.0 | 0.0 |
| IJJCEOHG_16 | 0.0 | 1.0 | 0.0 |
| IJJCEOHG_17 | 1.0 | 0.0 | 1.0 |
| IJJCEOHG_18 | 0.0 | 1.0 | 0.0 |
| IJJCEOHG_19 | 0.0 | 1.0 | 0.0 |
| IJJCEOHG_20 | 0.0 | 1.0 | 0.0 |
| IJJCEOHG_21 | 0.0 | 1.0 | 0.0 |
| IJJCEOHG_22 | 0.0 | 1.0 | 0.0 |
| IJJCEOHG_23 | 0.0 | 1.0 | 0.0 |
| IJJCEOHG_24 | 0.0 | 1.0 | 0.0 |
| IJJCEOHG_25 | 0.0 | 1.0 | 0.0 |
| IJJCEOHG_26 | 0.0 | 1.0 | 0.0 |
| IJJCEOHG_27 | 0.0 | 1.0 | 0.0 |
| IJJCEOHG_28 | 0.0 | 1.0 | 0.0 |
| IJJCEOHG_29 | 0.0 | 1.0 | 0.0 |
| IJJCEOHG_30 | 1.0 | 0.0 | 1.0 |
| IJJCEOHG_31 | 0.0 | 1.0 | 0.0 |
| IJJCEOHG_32 | 0.0 | 1.0 | 0.0 |
| IJJCEOHG_33 | 0.0 | 1.0 | 0.0 |
| IJJCEOHG_34 | 0.0 | 1.0 | 0.0 |
| IJJCEOHG_35 | 0.0 | 1.0 | 0.0 |
| IJJCEOHG_36 | 0.0 | 1.0 | 0.0 |
| IJJCEOHG_37 | 0.0 | 1.0 | 0.0 |
| IJJCEOHG_38 | 0.0 | 1.0 | 0.0 |
| IJJCEOHG_39 | 1.0 | 0.0 | 1.0 |
| IJJCEOHG_40 | 0.0 | 1.0 | 0.0 |
| IJJCEOHG_41 | 0.0 | 1.0 | 0.0 |
| IJJCEOHG_42 | 1.0 | 0.0 | 1.0 |
| IJJCEOHG_43 | 0.0 | 1.0 | 0.0 |
| IJJCEOHG_44 | 0.0 | 1.0 | 0.0 |
| IJJCEOHG_45 | 0.0 | 1.0 | 0.0 |
| IJJCEOHG_46 | 1.0 | 0.0 | 1.0 |
| IJJCEOHG_48 | 0.0 | 1.0 | 0.0 |
PlasmidHunter v 1.4.5 (Database: May. 2024 release)
Prophage
Phigaro
| Query ID | Begin | End | Transposable | Taxonomy | pVOGs |
|---|---|---|---|---|---|
| No hit found | |||||
Phigaro v2.4.0 (Database: Jan. 2024 release)