Probiotic potential risk score


ARGs VFs PGs PPRS
1303143.15

PPRS is classified as low-risk (≤4), medium-risk (4-6), and high-risk (≥6).

Antibiotic resistance genes


Comprehensive Antibiotic Resistance Database (CARD)

Query ID Begin End ARO name ARO accession CARD name Identity Coverage Accession no.
No hit found

RGI v6.0.3 (Database: CARD Variants v4.0.2, Nov. 2023 release)

ResFinder

Query ID Begin End Resistance gene Phenotype Identity Coverage Accession no.
No hit found

ResFinder v4.6.0 (Database: resfinder_db, Aug. 2024 release)

AMRFinderPlus

Query ID Begin End Gene symbol Sequence name Method Identity Coverage Accession no.
IBOLCLPD_16668487222qacHquaternary ammonium compound efflux SMR transporter QacHBLASTX99.20100.00WP_000121134.1

AMRFinderPlus v4.0.3 (Database: Oct. 2024 release)

Virulence factors


Virulence Factor Database (VFDB)

Query ID qstart qend Gene name e-value VF name VF category Identity Coverage Accession no.
IBOLCLPD_1441054011256STER_RS070850.0CapsuleImmune modulation100.00100.00WP_011681442
IBOLCLPD_144957110539STER_RS070900.0CapsuleImmune modulation100.00100.00WP_011681443
IBOLCLPD_14818423587STER_RS070450.0CapsuleImmune modulation99.94100.00WP_011681434
IBOLCLPD_1481821780STER_RS070500.0CapsuleImmune modulation99.9494.00WP_041827753
IBOLCLPD_1441249713645STER_RS070700.0CapsuleImmune modulation99.91100.00WP_011681439
IBOLCLPD_5112602315STU_RS162350.0CapsuleImmune modulation99.91100.00WP_002948022
IBOLCLPD_1441364214583STER_RS070650.0CapsuleImmune modulation99.89100.00WP_011681438
IBOLCLPD_1441160212378STER_RS070750.0CapsuleImmune modulation99.87100.00WP_011681440
IBOLCLPD_1441538916509STER_RS070550.0CapsuleImmune modulation99.8293.18WP_011681436
IBOLCLPD_1481821780STR_RS068900.0CapsuleImmune modulation99.7594.00WP_041827077
IBOLCLPD_520982691STR_RS058800.0CapsuleImmune modulation99.66100.00WP_011226149
IBOLCLPD_1441458315389STER_RS070600.0CapsuleImmune modulation99.63100.00WP_011681437
IBOLCLPD_1441538916509STR_RS068950.0CapsuleImmune modulation99.5593.18WP_011227428
IBOLCLPD_520982691STER_RS060300.0CapsuleImmune modulation99.50100.00WP_011226149
IBOLCLPD_520982691STU_RS152600.0CapsuleImmune modulation99.50100.00WP_011226149
IBOLCLPD_51351240STU_RS162400.0CapsuleImmune modulation99.42100.00WP_011226326
IBOLCLPD_22198523643fbp540.0FBPsAdherence99.40100.00WP_011227179
IBOLCLPD_14485769553STER_RS070950.0CapsuleImmune modulation99.39100.00WP_011681444
IBOLCLPD_1441364214583STR_RS069050.0CapsuleImmune modulation99.36100.00WP_011227430
IBOLCLPD_1441249713645STR_RS069100.0CapsuleImmune modulation99.30100.00WP_011227431
IBOLCLPD_1441458315389STR_RS069000.0CapsuleImmune modulation99.13100.00WP_011227429
IBOLCLPD_512292098rfbA0.0CapsuleImmune modulation99.08100.00WP_011681286
IBOLCLPD_15422653234cbpD0.0AutolysinExoenzyme98.76100.00WP_082302295
IBOLCLPD_16729023663srtA0.0Sortase AExoenzyme98.69100.00-
IBOLCLPD_14463517202rfbD0.0CapsuleImmune modulation98.47100.00WP_014621820
IBOLCLPD_12713172105cshA0.0Cell surface hydrophobicity proteinsAdherence98.3699.75-
IBOLCLPD_14818423587STR_RS068850.0CapsuleImmune modulation98.28100.00WP_011227426
IBOLCLPD_622303690STER_RS053200.0CapsuleImmune modulation97.88100.00WP_011681177
IBOLCLPD_636914422STER_RS053150.0CapsuleImmune modulation97.40100.00WP_011681176
IBOLCLPD_636914422STU_RS146450.0CapsuleImmune modulation97.40100.00WP_011226048
IBOLCLPD_636914422STR_RS052600.0CapsuleImmune modulation97.27100.00WP_011227248
IBOLCLPD_622303690STU_RS146500.0CapsuleImmune modulation97.26100.21WP_011226049
IBOLCLPD_644315123STU_RS146400.0CapsuleImmune modulation97.26100.00WP_011226047
IBOLCLPD_644315123STR_RS052550.0CapsuleImmune modulation96.97100.00WP_011227247
IBOLCLPD_622303690STR_RS052650.0CapsuleImmune modulation96.44100.21WP_041827043
IBOLCLPD_14473218579STER_RS071000.0CapsuleImmune modulation96.4399.92WP_011681445
IBOLCLPD_11238968791SAG_RS091050.0Agglutinin receptorAdherence95.8199.96WP_000167699
IBOLCLPD_11238488791SSU98_09780.0Agglutinin receptorAdherence95.7399.78YP_001200536
IBOLCLPD_11238488791SSU05_09650.0Agglutinin receptorAdherence95.7199.78YP_001198331
IBOLCLPD_20638835248STER_RS053000.0CapsuleImmune modulation95.3199.85WP_011681173
IBOLCLPD_20638815248STU_RS146300.0CapsuleImmune modulation94.37100.00WP_011226045
IBOLCLPD_644315123STER_RS053100.0CapsuleImmune modulation90.77100.00WP_011681175
IBOLCLPD_121305eno0.0Streptococcal enolaseExoenzyme87.9499.54WP_000022832
IBOLCLPD_14114592469plr/gapA0.0Streptococcal plasmin receptor/GAPDHAdherence86.7499.41WP_002986042
IBOLCLPD_1441458315389SGO_RS050200.0CapsuleImmune modulation83.27100.00WP_012000440
IBOLCLPD_13625773860tig/ropA0.0Trigger factorStress survival80.7399.77WP_000107753
IBOLCLPD_531214167rfbB0.0CapsuleImmune modulation80.61100.00WP_009659423
IBOLCLPD_19511851768SPD_RS017758.73e-146CapsuleImmune modulation82.7396.20WP_001819836
IBOLCLPD_20653055760STU_RS146350.0CapsuleImmune modulation98.9061.54WP_011226046
IBOLCLPD_20653055760STER_RS053050.0CapsuleImmune modulation97.8161.54WP_011681174
IBOLCLPD_20653105760STR_RS052500.0CapsuleImmune modulation97.3460.13WP_011227246
IBOLCLPD_1441538916126SGO_RS050250.0CapsuleImmune modulation84.9660.29WP_012000441

BLASTN v2.16.0 (Database: VFDB, Dec. 2024 release)

VirulenceFinder

Query ID Begin End Database Virulence factor Protein function Identity Coverage Accession no.
No hit found

VirulenceFinder v2.0. 4 (Database: virulencefinder_db, Feb . 2024 release)

Pathogenic genes


PHI-base

Query ID qstart qend Gene name e-value Function Identity Coverage Gene ID
IBOLCLPD_11238758788B9H01_RS047650.0glucan-binding protein97.1999.70AUS90958
IBOLCLPD_1341365512582MntE0.0manganese homeostasis94.9799.72ABF32167
IBOLCLPD_16763507333ldh(Sp_1220)0.0L-lactate dehydrogenase94.82100.00AAK75326
IBOLCLPD_16270728553SPD_03100.0UPF0371 protein SPD_031091.90100.00ABJ54480
IBOLCLPD_1351301510769metE0.0methionine biosynthesis enzymes91.72100.00AAK74738
IBOLCLPD_20152996300recA0.0DNA recombination and repair91.0286.08AAL00560
IBOLCLPD_1631218511214prsA20.0ribose-phosphate pyrophosphokinase90.12100.00ABF36968
IBOLCLPD_13045105661potA0.0ABC transporter ATP-binding protein-spermidine/putrescine transport89.3299.74AAL00050
IBOLCLPD_14975879575uvrB0.0excinuclease ABC, B subunit89.14100.00AE014259_2
IBOLCLPD_57950511235ptsI0.0phosphoenolpyruvate-protein phosphotransferase88.04100.00AAK34199
IBOLCLPD_197114719993IMPDH0.0inosine-5'-monophosphate dehydrogenase87.83100.00ADE32434
IBOLCLPD_113054Eno0.0enolase85.9899.77ABP90468
IBOLCLPD_1521285610964gidA0.0tRNA uridine 5-carboxymethylaminomethyl modification enzyme85.4298.90ABP91129
IBOLCLPD_13578449553PGM0.0phosphoglucomutase84.0699.65ACH87041
IBOLCLPD_682006521075pdh0.0pyruvate dehydrogenase83.0999.70ABP91006
IBOLCLPD_285969957mnmE0.0central tRNA-modifying GTPase82.0299.56ABP90420
IBOLCLPD_1281704715155PepO0.0endopeptidase80.03100.00ABF32980
IBOLCLPD_11573714847bglB4.93e-180putative phospho--glucosidase88.8999.66AAK33487
IBOLCLPD_13129673905SP_06767.50e-169transcription facot81.1597.20AAK74821
IBOLCLPD_135105779720metF5.23e-167methionine biosynthesis enzymes86.3699.31AAK74739
IBOLCLPD_352438923685covR7.32e-133responder protein85.53100.00AAK71319
IBOLCLPD_13538903222CiaR5.75e-126two-component response regulator87.4499.55AAK74935
IBOLCLPD_13538903219ciaR6.17e-124two component system response regulator85.2799.12AIK75708
IBOLCLPD_352438923685walR3.08e-123DNA-binding response regulator82.13100.00ANC99504
IBOLCLPD_15763625676CovR2.21e-120serves to repress GAS virulence factor-encoding genes81.22100.00ACE75886
IBOLCLPD_20743334620spr04791.72e-49essential gene84.3898.97AAK99283
IBOLCLPD_17925362282spr13271.35e-46essential gene95.29100.00AAL00131
IBOLCLPD_1131252912266spr01751.15e-41pathogenitcity related82.95100.00AAK98979
IBOLCLPD_1131170211436spr01774.83e-34essential gene84.2788.12AAK98981
IBOLCLPD_13640184518RopE (M5005_Spy_1611)3.46e-77probable DNA-directed RNA polymerase subunit delta82.0487.43AAK34603
IBOLCLPD_24108949704AUS90997 (B9H01_RS07385)0.0site-specific integrase88.6799.50AUS90997
IBOLCLPD_12826101591ilvC (SPD_0406)0.0ketol-acid reductoisomerase (NADP(+))96.47100.00ABJ55451
IBOLCLPD_853191494HMPREF0351_10118 (WxL locusC)0.0involved in bile salt stress and endocarditis pathogenesis100.00100.00HMPREF0351_10118
IBOLCLPD_3732052735rr014.18e-87response regulator84.7169.78CAB54566

BLASTX v2.16.0 (Database: PHI base v4.16, May. 2024 release)

Plasmid


PlasmidFinder

Query ID Begin End Plasmid Query / Template Identity Accession no.
No hit found

PlasmidFinder v 2.1.6 (Database: plasmidfinder_db v 2.2.0 , Nov. 2024 release)

PlasmidHunter

Query ID Prediction Chromosome Plasmid
IBOLCLPD_10.01.00.0
IBOLCLPD_20.01.00.0
IBOLCLPD_30.01.00.0
IBOLCLPD_40.01.00.0
IBOLCLPD_50.01.00.0
IBOLCLPD_60.01.00.0
IBOLCLPD_70.01.00.0
IBOLCLPD_81.00.01.0
IBOLCLPD_90.01.00.0
IBOLCLPD_100.01.00.0
IBOLCLPD_110.01.00.0
IBOLCLPD_120.01.00.0
IBOLCLPD_130.01.00.0
IBOLCLPD_140.01.00.0
IBOLCLPD_150.01.00.0
IBOLCLPD_160.01.00.0
IBOLCLPD_170.01.00.0
IBOLCLPD_180.01.00.0
IBOLCLPD_190.01.00.0
IBOLCLPD_200.01.00.0
IBOLCLPD_211.00.01.0
IBOLCLPD_221.00.01.0
IBOLCLPD_230.01.00.0
IBOLCLPD_240.01.00.0
IBOLCLPD_250.01.00.0
IBOLCLPD_260.01.00.0
IBOLCLPD_270.01.00.0
IBOLCLPD_280.01.00.0
IBOLCLPD_290.01.00.0
IBOLCLPD_300.01.00.0
IBOLCLPD_310.01.00.0
IBOLCLPD_320.01.00.0
IBOLCLPD_331.00.01.0
IBOLCLPD_341.00.01.0
IBOLCLPD_350.01.00.0
IBOLCLPD_360.01.00.0
IBOLCLPD_370.01.00.0
IBOLCLPD_380.01.00.0
IBOLCLPD_391.00.01.0
IBOLCLPD_401.00.01.0
IBOLCLPD_420.01.00.0
IBOLCLPD_430.01.00.0
IBOLCLPD_440.01.00.0
IBOLCLPD_451.00.01.0
IBOLCLPD_460.01.00.0
IBOLCLPD_471.00.01.0
IBOLCLPD_480.01.00.0
IBOLCLPD_490.01.00.0
IBOLCLPD_500.01.00.0
IBOLCLPD_510.01.00.0
IBOLCLPD_520.01.00.0
IBOLCLPD_531.00.01.0
IBOLCLPD_540.01.00.0
IBOLCLPD_550.01.00.0
IBOLCLPD_560.01.00.0
IBOLCLPD_570.01.00.0
IBOLCLPD_581.00.01.0
IBOLCLPD_590.01.00.0
IBOLCLPD_600.01.00.0
IBOLCLPD_611.00.01.0
IBOLCLPD_620.01.00.0
IBOLCLPD_630.01.00.0
IBOLCLPD_641.00.01.0
IBOLCLPD_650.01.00.0
IBOLCLPD_660.01.00.0
IBOLCLPD_680.01.00.0
IBOLCLPD_690.01.00.0
IBOLCLPD_710.01.00.0
IBOLCLPD_720.01.00.0
IBOLCLPD_731.00.01.0
IBOLCLPD_740.01.00.0
IBOLCLPD_750.01.00.0
IBOLCLPD_760.01.00.0
IBOLCLPD_770.01.00.0
IBOLCLPD_781.00.01.0
IBOLCLPD_790.01.00.0
IBOLCLPD_801.00.01.0
IBOLCLPD_810.01.00.0
IBOLCLPD_821.00.01.0
IBOLCLPD_830.01.00.0
IBOLCLPD_841.00.01.0
IBOLCLPD_851.00.01.0
IBOLCLPD_861.00.01.0
IBOLCLPD_870.01.00.0
IBOLCLPD_880.01.00.0
IBOLCLPD_891.00.01.0
IBOLCLPD_900.01.00.0
IBOLCLPD_910.01.00.0
IBOLCLPD_931.00.01.0
IBOLCLPD_941.00.01.0
IBOLCLPD_951.00.01.0
IBOLCLPD_960.01.00.0
IBOLCLPD_970.01.00.0
IBOLCLPD_980.01.00.0
IBOLCLPD_990.01.00.0
IBOLCLPD_1001.00.01.0
IBOLCLPD_1010.01.00.0
IBOLCLPD_1021.00.01.0
IBOLCLPD_1031.00.01.0
IBOLCLPD_1041.00.01.0
IBOLCLPD_1050.01.00.0
IBOLCLPD_1060.01.00.0
IBOLCLPD_1071.00.01.0
IBOLCLPD_1080.01.00.0
IBOLCLPD_1090.01.00.0
IBOLCLPD_1100.01.00.0
IBOLCLPD_1110.01.00.0
IBOLCLPD_1120.01.00.0
IBOLCLPD_1130.01.00.0
IBOLCLPD_1141.00.01.0
IBOLCLPD_1151.00.01.0
IBOLCLPD_1160.01.00.0
IBOLCLPD_1170.01.00.0
IBOLCLPD_1180.01.00.0
IBOLCLPD_1191.00.01.0
IBOLCLPD_1201.00.01.0
IBOLCLPD_1211.00.01.0
IBOLCLPD_1220.01.00.0
IBOLCLPD_1230.01.00.0
IBOLCLPD_1240.01.00.0
IBOLCLPD_1250.01.00.0
IBOLCLPD_1260.01.00.0
IBOLCLPD_1270.01.00.0
IBOLCLPD_1280.01.00.0
IBOLCLPD_1290.01.00.0
IBOLCLPD_1300.01.00.0
IBOLCLPD_1310.01.00.0
IBOLCLPD_1320.01.00.0
IBOLCLPD_1330.01.00.0
IBOLCLPD_1340.01.00.0
IBOLCLPD_1350.01.00.0
IBOLCLPD_1360.01.00.0
IBOLCLPD_1370.01.00.0
IBOLCLPD_1380.01.00.0
IBOLCLPD_1390.01.00.0
IBOLCLPD_1400.01.00.0
IBOLCLPD_1410.01.00.0
IBOLCLPD_1420.01.00.0
IBOLCLPD_1430.01.00.0
IBOLCLPD_1440.01.00.0
IBOLCLPD_1450.01.00.0
IBOLCLPD_1460.01.00.0
IBOLCLPD_1470.01.00.0
IBOLCLPD_1480.01.00.0
IBOLCLPD_1490.01.00.0
IBOLCLPD_1500.01.00.0
IBOLCLPD_1510.01.00.0
IBOLCLPD_1520.01.00.0
IBOLCLPD_1530.01.00.0
IBOLCLPD_1540.01.00.0
IBOLCLPD_1550.01.00.0
IBOLCLPD_1560.01.00.0
IBOLCLPD_1570.01.00.0
IBOLCLPD_1580.01.00.0
IBOLCLPD_1590.01.00.0
IBOLCLPD_1600.01.00.0
IBOLCLPD_1610.01.00.0
IBOLCLPD_1620.01.00.0
IBOLCLPD_1630.01.00.0
IBOLCLPD_1640.01.00.0
IBOLCLPD_1650.01.00.0
IBOLCLPD_1661.00.01.0
IBOLCLPD_1670.01.00.0
IBOLCLPD_1680.01.00.0
IBOLCLPD_1690.01.00.0
IBOLCLPD_1700.01.00.0
IBOLCLPD_1710.01.00.0
IBOLCLPD_1720.01.00.0
IBOLCLPD_1730.01.00.0
IBOLCLPD_1740.01.00.0
IBOLCLPD_1750.01.00.0
IBOLCLPD_1760.01.00.0
IBOLCLPD_1770.01.00.0
IBOLCLPD_1780.01.00.0
IBOLCLPD_1790.01.00.0
IBOLCLPD_1800.01.00.0
IBOLCLPD_1810.01.00.0
IBOLCLPD_1820.01.00.0
IBOLCLPD_1830.01.00.0
IBOLCLPD_1840.01.00.0
IBOLCLPD_1851.00.01.0
IBOLCLPD_1860.01.00.0
IBOLCLPD_1870.01.00.0
IBOLCLPD_1880.01.00.0
IBOLCLPD_1890.01.00.0
IBOLCLPD_1900.01.00.0
IBOLCLPD_1910.01.00.0
IBOLCLPD_1920.01.00.0
IBOLCLPD_1930.01.00.0
IBOLCLPD_1940.01.00.0
IBOLCLPD_1950.01.00.0
IBOLCLPD_1961.00.01.0
IBOLCLPD_1970.01.00.0
IBOLCLPD_1980.01.00.0
IBOLCLPD_1990.01.00.0
IBOLCLPD_2000.01.00.0
IBOLCLPD_2010.01.00.0
IBOLCLPD_2020.01.00.0
IBOLCLPD_2030.01.00.0
IBOLCLPD_2040.01.00.0
IBOLCLPD_2051.00.01.0
IBOLCLPD_2060.01.00.0
IBOLCLPD_2070.01.00.0

PlasmidHunter v 1.4.5 (Database: May. 2024 release)

Prophage


Phigaro

Query ID Begin End Transposable Taxonomy pVOGs
IBOLCLPD_164101139099FalseSiphoviridaeVOG3301, VOG3300, VOG3299, VOG4649, VOG0054, VOG3424, VOG3298, VOG4782, VOG0647, VOG4599, VOG4605, VOG0800, VOG0725, VOG0799, VOG0724, VOG5660, VOG0723, VOG4713, VOG3435, VOG1887, VOG3434, VOG4555, VOG4564, VOG0720, VOG4544, VOG0796, VOG0198, VOG0658, VOG0044, VOG0657, VOG0152, VOG0044, VOG0152, VOG0656, VOG3468, VOG0655, VOG4693, VOG0226, VOG0685, VOG0283, VOG3430, VOG0189, VOG4566, VOG0651, VOG8482, VOG3478, VOG9469, VOG1564, VOG3622, VOG0743

Phigaro v2.4.0 (Database: Jan. 2024 release)


Insertion sequence (IS) elements