Probiotic potential risk score
| ARGs | VFs | PGs | PPRS |
|---|---|---|---|
| 0 | 26 | 34 | 42.80 |
PPRS is classified as low-risk (≤4), medium-risk (4-6), and high-risk (≥6).
Antibiotic resistance genes
Comprehensive Antibiotic Resistance Database (CARD)
| Query ID | Begin | End | ARO name | ARO accession | CARD name | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
RGI v6.0.3 (Database: CARD Variants v4.0.2, Nov. 2023 release)
ResFinder
| Query ID | Begin | End | Resistance gene | Phenotype | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|
| No hit found | |||||||
ResFinder v4.6.0 (Database: resfinder_db, Aug. 2024 release)
AMRFinderPlus
| Query ID | Begin | End | Gene symbol | Sequence name | Method | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
AMRFinderPlus v4.0.3 (Database: Oct. 2024 release)
Virulence factors
Virulence Factor Database (VFDB)
| Query ID | qstart | qend | Gene name | e-value | VF name | VF category | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|---|
| EOIICCNB_23 | 129490 | 130083 | STR_RS05880 | 0.0 | Capsule | Immune modulation | 100.00 | 100.00 | WP_011226149 |
| EOIICCNB_89 | 61525 | 62481 | STU_RS16250 | 0.0 | Capsule | Immune modulation | 99.90 | 100.00 | WP_011226328 |
| EOIICCNB_23 | 129490 | 130083 | STER_RS06030 | 0.0 | Capsule | Immune modulation | 99.83 | 100.00 | WP_011226149 |
| EOIICCNB_23 | 129490 | 130083 | STU_RS15260 | 0.0 | Capsule | Immune modulation | 99.83 | 100.00 | WP_011226149 |
| EOIICCNB_89 | 60380 | 61528 | STU_RS16255 | 0.0 | Capsule | Immune modulation | 99.83 | 100.00 | WP_041828290 |
| EOIICCNB_23 | 128621 | 129490 | rfbA | 0.0 | Capsule | Immune modulation | 99.66 | 100.00 | WP_011681286 |
| EOIICCNB_89 | 64499 | 65554 | STU_RS16235 | 0.0 | Capsule | Immune modulation | 99.62 | 100.00 | WP_002948022 |
| EOIICCNB_89 | 63274 | 64479 | STU_RS16240 | 0.0 | Capsule | Immune modulation | 99.58 | 100.00 | WP_011226326 |
| EOIICCNB_89 | 62465 | 63274 | STU_RS16245 | 0.0 | Capsule | Immune modulation | 99.51 | 100.00 | WP_002948020 |
| EOIICCNB_89 | 65551 | 67335 | STU_RS16230 | 0.0 | Capsule | Immune modulation | 99.50 | 100.00 | WP_011226325 |
| EOIICCNB_78 | 31931 | 33589 | fbp54 | 0.0 | FBPs | Adherence | 99.40 | 100.00 | WP_011227179 |
| EOIICCNB_2 | 69037 | 69729 | STU_RS14640 | 0.0 | Capsule | Immune modulation | 99.28 | 100.00 | WP_011226047 |
| EOIICCNB_2 | 74716 | 76131 | STER_RS05250 | 0.0 | Capsule | Immune modulation | 99.22 | 100.00 | WP_011681165 |
| EOIICCNB_2 | 68297 | 69028 | STR_RS05260 | 0.0 | Capsule | Immune modulation | 99.18 | 100.00 | WP_011227248 |
| EOIICCNB_2 | 69037 | 69729 | STR_RS05255 | 0.0 | Capsule | Immune modulation | 98.99 | 100.00 | WP_011227247 |
| EOIICCNB_2 | 69739 | 70479 | STER_RS05305 | 0.0 | Capsule | Immune modulation | 98.92 | 100.00 | WP_011681174 |
| EOIICCNB_2 | 69739 | 70479 | STU_RS14635 | 0.0 | Capsule | Immune modulation | 98.78 | 100.00 | WP_011226046 |
| EOIICCNB_2 | 1461 | 2251 | cshA | 0.0 | Cell surface hydrophobicity proteins | Adherence | 98.74 | 99.87 | - |
| EOIICCNB_23 | 93963 | 94724 | srtA | 0.0 | Sortase A | Exoenzyme | 98.69 | 100.00 | - |
| EOIICCNB_89 | 57722 | 58684 | STU_RS16260 | 0.0 | Capsule | Immune modulation | 98.65 | 95.25 | WP_011226330 |
| EOIICCNB_89 | 56448 | 57722 | STU_RS16265 | 0.0 | Capsule | Immune modulation | 98.35 | 100.00 | WP_011226331 |
| EOIICCNB_2 | 68297 | 69028 | STU_RS14645 | 0.0 | Capsule | Immune modulation | 98.22 | 100.00 | WP_011226048 |
| EOIICCNB_2 | 69739 | 70474 | STR_RS05250 | 0.0 | Capsule | Immune modulation | 98.10 | 98.13 | WP_011227246 |
| EOIICCNB_2 | 66836 | 68296 | STER_RS05320 | 0.0 | Capsule | Immune modulation | 98.02 | 100.00 | WP_011681177 |
| EOIICCNB_2 | 68297 | 69028 | STER_RS05315 | 0.0 | Capsule | Immune modulation | 97.95 | 100.00 | WP_011681176 |
| EOIICCNB_89 | 54496 | 55347 | rfbD | 0.0 | Capsule | Immune modulation | 97.65 | 100.00 | WP_014621820 |
| EOIICCNB_1 | 255677 | 256637 | cbpD | 0.0 | Autolysin | Exoenzyme | 97.32 | 99.90 | WP_082302295 |
| EOIICCNB_2 | 70537 | 71904 | STU_RS14630 | 0.0 | Capsule | Immune modulation | 97.30 | 100.00 | WP_011226045 |
| EOIICCNB_2 | 66836 | 68296 | STU_RS14650 | 0.0 | Capsule | Immune modulation | 96.99 | 100.21 | WP_011226049 |
| EOIICCNB_1 | 54043 | 58996 | SSU98_0978 | 0.0 | Agglutinin receptor | Adherence | 96.19 | 100.00 | YP_001200536 |
| EOIICCNB_2 | 66836 | 68296 | STR_RS05265 | 0.0 | Capsule | Immune modulation | 96.17 | 100.21 | WP_041827043 |
| EOIICCNB_1 | 54043 | 58996 | SSU05_0965 | 0.0 | Agglutinin receptor | Adherence | 96.17 | 100.00 | YP_001198331 |
| EOIICCNB_1 | 54043 | 58938 | SAG_RS09105 | 0.0 | Agglutinin receptor | Adherence | 96.12 | 100.00 | WP_000167699 |
| EOIICCNB_2 | 70537 | 71900 | STER_RS05300 | 0.0 | Capsule | Immune modulation | 94.06 | 99.71 | WP_011681173 |
| EOIICCNB_2 | 69037 | 69729 | STER_RS05310 | 0.0 | Capsule | Immune modulation | 89.47 | 100.00 | WP_011681175 |
| EOIICCNB_1 | 92268 | 93571 | eno | 0.0 | Streptococcal enolase | Exoenzyme | 88.02 | 99.46 | WP_000022832 |
| EOIICCNB_19 | 14446 | 15456 | plr/gapA | 0.0 | Streptococcal plasmin receptor/GAPDH | Adherence | 87.02 | 99.51 | WP_002986042 |
| EOIICCNB_12 | 7281 | 8564 | tig/ropA | 0.0 | Trigger factor | Stress survival | 80.65 | 99.77 | WP_000107753 |
| EOIICCNB_23 | 130512 | 131558 | rfbB | 0.0 | Capsule | Immune modulation | 80.52 | 100.00 | WP_009659423 |
BLASTN v2.16.0 (Database: VFDB, Dec. 2024 release)
VirulenceFinder
| Query ID | Begin | End | Database | Virulence factor | Protein function | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
VirulenceFinder v2.0. 4 (Database: virulencefinder_db, Feb . 2024 release)
Pathogenic genes
PHI-base
| Query ID | qstart | qend | Gene name | e-value | Function | Identity | Coverage | Gene ID |
|---|---|---|---|---|---|---|---|---|
| EOIICCNB_1 | 58974 | 54046 | B9H01_RS04765 | 0.0 | glucan-binding protein | 95.50 | 100.00 | AUS90958 |
| EOIICCNB_23 | 91276 | 90293 | ldh(Sp_1220) | 0.0 | L-lactate dehydrogenase | 94.82 | 100.00 | AAK75326 |
| EOIICCNB_67 | 31915 | 30842 | MntE | 0.0 | manganese homeostasis | 94.41 | 99.72 | ABF32167 |
| EOIICCNB_56 | 9669 | 7366 | pfl2(Sp_0459) | 0.0 | formate acetyltransferase | 92.84 | 99.22 | AAK74619 |
| EOIICCNB_1 | 180697 | 179729 | spr0084 | 0.0 | pathogenitcity related | 92.57 | 98.48 | AAK98888 |
| EOIICCNB_67 | 11392 | 9146 | metE | 0.0 | methionine biosynthesis enzymes | 91.99 | 100.00 | AAK74738 |
| EOIICCNB_23 | 11150 | 9669 | SPD_0310 | 0.0 | UPF0371 protein SPD_0310 | 91.70 | 100.00 | ABJ54480 |
| EOIICCNB_20 | 12156 | 13154 | recA | 0.0 | DNA recombination and repair | 91.29 | 85.82 | AAL00560 |
| EOIICCNB_16 | 4298 | 5269 | prsA2 | 0.0 | ribose-phosphate pyrophosphokinase | 90.12 | 100.00 | ABF36968 |
| EOIICCNB_89 | 5280 | 6431 | potA | 0.0 | ABC transporter ATP-binding protein-spermidine/putrescine transport | 89.32 | 99.74 | AAL00050 |
| EOIICCNB_89 | 41319 | 43307 | uvrB | 0.0 | excinuclease ABC, B subunit | 88.99 | 100.00 | AE014259_2 |
| EOIICCNB_23 | 107471 | 109201 | ptsI | 0.0 | phosphoenolpyruvate-protein phosphotransferase | 88.04 | 100.00 | AAK34199 |
| EOIICCNB_34 | 27979 | 29457 | IMPDH | 0.0 | inosine-5'-monophosphate dehydrogenase | 87.42 | 100.00 | ADE32434 |
| EOIICCNB_1 | 93571 | 92270 | Eno | 0.0 | enolase | 86.44 | 99.77 | ABP90468 |
| EOIICCNB_34 | 42714 | 44606 | gidA | 0.0 | tRNA uridine 5-carboxymethylaminomethyl modification enzyme | 85.89 | 98.90 | ABP91129 |
| EOIICCNB_67 | 6221 | 7930 | PGM | 0.0 | phosphoglucomutase | 84.06 | 99.65 | ACH87041 |
| EOIICCNB_8 | 23442 | 22432 | pdh | 0.0 | pyruvate dehydrogenase | 82.79 | 99.70 | ABP91006 |
| EOIICCNB_78 | 59359 | 57998 | mnmE | 0.0 | central tRNA-modifying GTPase | 82.24 | 99.56 | ABP90420 |
| EOIICCNB_7 | 4764 | 6656 | PepO | 0.0 | endopeptidase | 80.03 | 100.00 | ABF32980 |
| EOIICCNB_1 | 108011 | 107121 | bglB | 8.44e-179 | putative phospho--glucosidase | 88.55 | 99.66 | AAK33487 |
| EOIICCNB_10 | 15969 | 16904 | SP_0676 | 1.08e-169 | transcription facot | 81.73 | 96.89 | AAK74821 |
| EOIICCNB_67 | 8954 | 8097 | metF | 8.40e-166 | methionine biosynthesis enzymes | 86.36 | 99.31 | AAK74739 |
| EOIICCNB_2 | 29986 | 30690 | covR | 1.80e-132 | responder protein | 85.53 | 100.00 | AAK71319 |
| EOIICCNB_23 | 39167 | 39838 | rr01 | 2.96e-125 | response regulator | 83.93 | 99.56 | CAB54566 |
| EOIICCNB_2 | 29986 | 30690 | walR | 7.60e-123 | DNA-binding response regulator | 82.13 | 100.00 | ANC99504 |
| EOIICCNB_12 | 161647 | 162333 | CovR | 1.03e-118 | serves to repress GAS virulence factor-encoding genes | 80.79 | 100.00 | ACE75886 |
| EOIICCNB_67 | 2267 | 1599 | CiaR | 1.11e-118 | two-component response regulator | 84.31 | 99.55 | AAK74935 |
| EOIICCNB_67 | 2267 | 1596 | ciaR | 1.09e-116 | two component system response regulator | 82.14 | 99.12 | AIK75708 |
| EOIICCNB_20 | 13430 | 13825 | SpxA2 | 2.80e-76 | transcriptional regulator | 90.91 | 100.00 | ERL21461 |
| EOIICCNB_78 | 70620 | 71021 | SpxA1 | 1.84e-67 | transcriptional regulator | 80.60 | 100.00 | ERL19273 |
| EOIICCNB_12 | 184060 | 184347 | spr0479 | 1.46e-48 | essential gene | 86.46 | 98.97 | AAK99283 |
| EOIICCNB_1 | 215262 | 215008 | spr1327 | 4.44e-45 | essential gene | 95.29 | 100.00 | AAL00131 |
| EOIICCNB_34 | 76327 | 76064 | spr0175 | 5.48e-42 | pathogenitcity related | 84.09 | 100.00 | AAK98979 |
| EOIICCNB_34 | 75500 | 75234 | spr0177 | 9.69e-34 | essential gene | 84.27 | 88.12 | AAK98981 |
| EOIICCNB_12 | 8722 | 9222 | RopE (M5005_Spy_1611) | 5.06e-76 | probable DNA-directed RNA polymerase subunit delta | 81.44 | 87.43 | AAK34603 |
| EOIICCNB_56 | 9669 | 7372 | PFL (B9H01_RS01125) | 0.0 | formate C-acetyltransferase | 82.81 | 98.08 | MYN69560 |
| EOIICCNB_7 | 19221 | 20240 | ilvC (SPD_0406) | 0.0 | ketol-acid reductoisomerase (NADP(+)) | 96.47 | 100.00 | ABJ55451 |
BLASTX v2.16.0 (Database: PHI base v4.16, May. 2024 release)
Plasmid
PlasmidFinder
| Query ID | Begin | End | Plasmid | Query / Template | Identity | Accession no. |
|---|---|---|---|---|---|---|
| No hit found | ||||||
PlasmidFinder v 2.1.6 (Database: plasmidfinder_db v 2.2.0 , Nov. 2024 release)
PlasmidHunter
| Query ID | Prediction | Chromosome | Plasmid |
|---|---|---|---|
| EOIICCNB_1 | 0.0 | 1.0 | 0.0 |
| EOIICCNB_2 | 0.0 | 1.0 | 0.0 |
| EOIICCNB_3 | 0.0 | 1.0 | 0.0 |
| EOIICCNB_4 | 0.0 | 1.0 | 0.0 |
| EOIICCNB_5 | 0.0 | 1.0 | 0.0 |
| EOIICCNB_6 | 0.0 | 1.0 | 0.0 |
| EOIICCNB_7 | 0.0 | 1.0 | 0.0 |
| EOIICCNB_8 | 0.0 | 1.0 | 0.0 |
| EOIICCNB_9 | 0.0 | 1.0 | 0.0 |
| EOIICCNB_10 | 0.0 | 1.0 | 0.0 |
| EOIICCNB_11 | 0.0 | 1.0 | 0.0 |
| EOIICCNB_12 | 0.0 | 1.0 | 0.0 |
| EOIICCNB_13 | 0.0 | 1.0 | 0.0 |
| EOIICCNB_14 | 0.0 | 1.0 | 0.0 |
| EOIICCNB_15 | 0.0 | 1.0 | 0.0 |
| EOIICCNB_16 | 0.0 | 1.0 | 0.0 |
| EOIICCNB_17 | 0.0 | 1.0 | 0.0 |
| EOIICCNB_18 | 0.0 | 1.0 | 0.0 |
| EOIICCNB_19 | 0.0 | 1.0 | 0.0 |
| EOIICCNB_20 | 0.0 | 1.0 | 0.0 |
| EOIICCNB_21 | 0.0 | 1.0 | 0.0 |
| EOIICCNB_22 | 0.0 | 1.0 | 0.0 |
| EOIICCNB_23 | 0.0 | 1.0 | 0.0 |
| EOIICCNB_24 | 0.0 | 1.0 | 0.0 |
| EOIICCNB_25 | 0.0 | 1.0 | 0.0 |
| EOIICCNB_26 | 1.0 | 0.0 | 1.0 |
| EOIICCNB_27 | 1.0 | 0.0 | 1.0 |
| EOIICCNB_28 | 1.0 | 0.0 | 1.0 |
| EOIICCNB_30 | 0.0 | 1.0 | 0.0 |
| EOIICCNB_31 | 1.0 | 0.0 | 1.0 |
| EOIICCNB_32 | 0.0 | 1.0 | 0.0 |
| EOIICCNB_33 | 0.0 | 1.0 | 0.0 |
| EOIICCNB_34 | 0.0 | 1.0 | 0.0 |
| EOIICCNB_35 | 1.0 | 0.0 | 1.0 |
| EOIICCNB_45 | 0.0 | 1.0 | 0.0 |
| EOIICCNB_56 | 0.0 | 1.0 | 0.0 |
| EOIICCNB_67 | 0.0 | 1.0 | 0.0 |
| EOIICCNB_78 | 0.0 | 1.0 | 0.0 |
| EOIICCNB_89 | 0.0 | 1.0 | 0.0 |
PlasmidHunter v 1.4.5 (Database: May. 2024 release)
Prophage
Phigaro
| Query ID | Begin | End | Transposable | Taxonomy | pVOGs |
|---|---|---|---|---|---|
| No hit found | |||||
Phigaro v2.4.0 (Database: Jan. 2024 release)