Probiotic potential risk score
| ARGs | VFs | PGs | PPRS |
|---|---|---|---|
| 0 | 23 | 33 | 40.22 |
PPRS is classified as low-risk (≤4), medium-risk (4-6), and high-risk (≥6).
Antibiotic resistance genes
Comprehensive Antibiotic Resistance Database (CARD)
| Query ID | Begin | End | ARO name | ARO accession | CARD name | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
RGI v6.0.3 (Database: CARD Variants v4.0.2, Nov. 2023 release)
ResFinder
| Query ID | Begin | End | Resistance gene | Phenotype | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|
| No hit found | |||||||
ResFinder v4.6.0 (Database: resfinder_db, Aug. 2024 release)
AMRFinderPlus
| Query ID | Begin | End | Gene symbol | Sequence name | Method | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
AMRFinderPlus v4.0.3 (Database: Oct. 2024 release)
Virulence factors
Virulence Factor Database (VFDB)
| Query ID | qstart | qend | Gene name | e-value | VF name | VF category | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|---|
| DMPCFEOA_1 | 93160 | 93753 | STR_RS05880 | 0.0 | Capsule | Immune modulation | 100.00 | 100.00 | WP_011226149 |
| DMPCFEOA_1 | 93160 | 93753 | STER_RS06030 | 0.0 | Capsule | Immune modulation | 99.83 | 100.00 | WP_011226149 |
| DMPCFEOA_1 | 93160 | 93753 | STU_RS15260 | 0.0 | Capsule | Immune modulation | 99.83 | 100.00 | WP_011226149 |
| DMPCFEOA_12 | 34531 | 35790 | STER_RS07100 | 0.0 | Capsule | Immune modulation | 99.76 | 100.00 | WP_011681445 |
| DMPCFEOA_4 | 39222 | 39821 | STR_RS05245 | 0.0 | Capsule | Immune modulation | 99.67 | 100.00 | WP_196767671 |
| DMPCFEOA_1 | 93753 | 94622 | rfbA | 0.0 | Capsule | Immune modulation | 99.66 | 100.00 | WP_011681286 |
| DMPCFEOA_15 | 7189 | 8028 | cbpD | 0.0 | Autolysin | Exoenzyme | 99.64 | 100.00 | WP_011226733 |
| DMPCFEOA_3 | 13601 | 15259 | fbp54 | 0.0 | FBPs | Adherence | 99.40 | 100.00 | WP_011227179 |
| DMPCFEOA_12 | 33558 | 34534 | STER_RS07095 | 0.0 | Capsule | Immune modulation | 99.39 | 99.90 | WP_011681444 |
| DMPCFEOA_12 | 32572 | 33540 | STER_RS07090 | 0.0 | Capsule | Immune modulation | 99.28 | 100.00 | WP_011681443 |
| DMPCFEOA_1 | 128520 | 129281 | srtA | 0.0 | Sortase A | Exoenzyme | 98.95 | 100.00 | - |
| DMPCFEOA_4 | 41419 | 42150 | STU_RS14645 | 0.0 | Capsule | Immune modulation | 98.77 | 100.00 | WP_011226048 |
| DMPCFEOA_1 | 43767 | 44557 | cshA | 0.0 | Cell surface hydrophobicity proteins | Adherence | 98.74 | 100.00 | - |
| DMPCFEOA_4 | 38098 | 39057 | STR_RS05240 | 0.0 | Capsule | Immune modulation | 98.65 | 100.00 | WP_041827042 |
| DMPCFEOA_4 | 39973 | 40708 | STU_RS14635 | 0.0 | Capsule | Immune modulation | 98.64 | 99.33 | WP_011226046 |
| DMPCFEOA_4 | 37214 | 37945 | STR_RS05220 | 0.0 | Capsule | Immune modulation | 98.63 | 75.08 | WP_011227240 |
| DMPCFEOA_4 | 41419 | 42150 | STER_RS05315 | 0.0 | Capsule | Immune modulation | 98.50 | 100.00 | WP_011681176 |
| DMPCFEOA_4 | 42151 | 43605 | STU_RS14650 | 0.0 | Capsule | Immune modulation | 98.42 | 100.00 | WP_011226049 |
| DMPCFEOA_4 | 39973 | 40708 | STER_RS05305 | 0.0 | Capsule | Immune modulation | 98.37 | 99.33 | WP_011681174 |
| DMPCFEOA_12 | 31855 | 32570 | STER_RS07085 | 0.0 | Capsule | Immune modulation | 98.32 | 99.86 | WP_011681442 |
| DMPCFEOA_4 | 39959 | 40708 | STR_RS05250 | 0.0 | Capsule | Immune modulation | 98.27 | 100.00 | WP_011227246 |
| DMPCFEOA_4 | 41419 | 42150 | STR_RS05260 | 0.0 | Capsule | Immune modulation | 98.09 | 100.00 | WP_011227248 |
| DMPCFEOA_12 | 35909 | 36760 | rfbD | 0.0 | Capsule | Immune modulation | 98.00 | 100.00 | WP_014621820 |
| DMPCFEOA_4 | 42151 | 43600 | STR_RS05265 | 0.0 | Capsule | Immune modulation | 97.72 | 99.66 | WP_041827043 |
| DMPCFEOA_12 | 30733 | 31509 | STER_RS07075 | 0.0 | Capsule | Immune modulation | 97.56 | 99.87 | WP_011681440 |
| DMPCFEOA_4 | 42151 | 43605 | STER_RS05320 | 0.0 | Capsule | Immune modulation | 96.72 | 99.79 | WP_011681177 |
| DMPCFEOA_4 | 40718 | 41410 | STR_RS05255 | 0.0 | Capsule | Immune modulation | 95.96 | 100.00 | WP_011227247 |
| DMPCFEOA_4 | 40718 | 41410 | STU_RS14640 | 0.0 | Capsule | Immune modulation | 95.96 | 100.00 | WP_011226047 |
| DMPCFEOA_4 | 40718 | 41410 | STER_RS05310 | 0.0 | Capsule | Immune modulation | 90.04 | 100.00 | WP_011681175 |
| DMPCFEOA_67 | 52910 | 54213 | eno | 0.0 | Streptococcal enolase | Exoenzyme | 88.09 | 99.54 | WP_000022832 |
| DMPCFEOA_23 | 95275 | 96285 | plr/gapA | 0.0 | Streptococcal plasmin receptor/GAPDH | Adherence | 86.92 | 99.51 | WP_002986042 |
| DMPCFEOA_24 | 5583 | 6866 | tig/ropA | 0.0 | Trigger factor | Stress survival | 80.65 | 99.77 | WP_000107753 |
| DMPCFEOA_1 | 91685 | 92731 | rfbB | 0.0 | Capsule | Immune modulation | 80.52 | 100.00 | WP_009659423 |
BLASTN v2.16.0 (Database: VFDB, Dec. 2024 release)
VirulenceFinder
| Query ID | Begin | End | Database | Virulence factor | Protein function | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
VirulenceFinder v2.0. 4 (Database: virulencefinder_db, Feb . 2024 release)
Pathogenic genes
PHI-base
| Query ID | qstart | qend | Gene name | e-value | Function | Identity | Coverage | Gene ID |
|---|---|---|---|---|---|---|---|---|
| DMPCFEOA_1 | 131968 | 132951 | ldh(Sp_1220) | 0.0 | L-lactate dehydrogenase | 94.82 | 100.00 | AAK75326 |
| DMPCFEOA_5 | 9192 | 8119 | MntE | 0.0 | manganese homeostasis | 94.41 | 99.72 | ABF32167 |
| DMPCFEOA_45 | 67899 | 66931 | spr0084 | 0.0 | pathogenitcity related | 93.19 | 98.48 | AAK98888 |
| DMPCFEOA_8 | 28053 | 25750 | pfl2(Sp_0459) | 0.0 | formate acetyltransferase | 93.10 | 99.22 | AAK74619 |
| DMPCFEOA_1 | 230237 | 231718 | SPD_0310 | 0.0 | UPF0371 protein SPD_0310 | 92.51 | 100.00 | ABJ54480 |
| DMPCFEOA_18 | 6027 | 8273 | metE | 0.0 | methionine biosynthesis enzymes | 92.12 | 100.00 | AAK74738 |
| DMPCFEOA_20 | 2026 | 1028 | recA | 0.0 | DNA recombination and repair | 91.29 | 85.82 | AAL00560 |
| DMPCFEOA_15 | 24511 | 23540 | prsA2 | 0.0 | ribose-phosphate pyrophosphokinase | 89.81 | 100.00 | ABF36968 |
| DMPCFEOA_12 | 78149 | 76998 | potA | 0.0 | ABC transporter ATP-binding protein-spermidine/putrescine transport | 89.06 | 99.74 | AAL00050 |
| DMPCFEOA_12 | 50105 | 48117 | uvrB | 0.0 | excinuclease ABC, B subunit | 88.99 | 100.00 | AE014259_2 |
| DMPCFEOA_1 | 115773 | 114043 | ptsI | 0.0 | phosphoenolpyruvate-protein phosphotransferase | 88.04 | 100.00 | AAK34199 |
| DMPCFEOA_56 | 493 | 1971 | IMPDH | 0.0 | inosine-5'-monophosphate dehydrogenase | 88.03 | 100.00 | ADE32434 |
| DMPCFEOA_67 | 54213 | 52912 | Eno | 0.0 | enolase | 86.44 | 99.77 | ABP90468 |
| DMPCFEOA_56 | 15689 | 17581 | gidA | 0.0 | tRNA uridine 5-carboxymethylaminomethyl modification enzyme | 86.05 | 98.90 | ABP91129 |
| DMPCFEOA_18 | 11198 | 9489 | PGM | 0.0 | phosphoglucomutase | 83.71 | 99.65 | ACH87041 |
| DMPCFEOA_34 | 22624 | 23634 | pdh | 0.0 | pyruvate dehydrogenase | 82.79 | 99.70 | ABP91006 |
| DMPCFEOA_3 | 33092 | 31731 | mnmE | 0.0 | central tRNA-modifying GTPase | 82.02 | 99.56 | ABP90420 |
| DMPCFEOA_34 | 72942 | 71050 | PepO | 0.0 | endopeptidase | 80.03 | 100.00 | ABF32980 |
| DMPCFEOA_67 | 68652 | 67762 | bglB | 5.11e-180 | putative phospho--glucosidase | 88.89 | 99.66 | AAK33487 |
| DMPCFEOA_6 | 17045 | 16107 | SP_0676 | 3.77e-169 | transcription facot | 81.15 | 97.20 | AAK74821 |
| DMPCFEOA_18 | 8465 | 9322 | metF | 7.86e-167 | methionine biosynthesis enzymes | 86.36 | 99.31 | AAK74739 |
| DMPCFEOA_1 | 16081 | 15377 | covR | 5.59e-132 | responder protein | 85.53 | 100.00 | AAK71319 |
| DMPCFEOA_1 | 198604 | 197933 | rr01 | 3.62e-124 | response regulator | 83.48 | 99.56 | CAB54566 |
| DMPCFEOA_1 | 16081 | 15377 | walR | 2.35e-122 | DNA-binding response regulator | 82.13 | 100.00 | ANC99504 |
| DMPCFEOA_89 | 49423 | 48737 | CovR | 3.62e-119 | serves to repress GAS virulence factor-encoding genes | 80.79 | 100.00 | ACE75886 |
| DMPCFEOA_18 | 15152 | 15820 | CiaR | 6.26e-119 | two-component response regulator | 84.31 | 99.55 | AAK74935 |
| DMPCFEOA_18 | 15152 | 15823 | ciaR | 4.84e-116 | two component system response regulator | 81.70 | 99.12 | AIK75708 |
| DMPCFEOA_20 | 752 | 378 | SpxA2 | 9.09e-72 | transcriptional regulator | 91.20 | 94.70 | ERL21461 |
| DMPCFEOA_3 | 44512 | 44913 | SpxA1 | 1.33e-67 | transcriptional regulator | 80.60 | 100.00 | ERL19273 |
| DMPCFEOA_89 | 27031 | 26744 | spr0479 | 9.43e-49 | essential gene | 85.42 | 98.97 | AAK99283 |
| DMPCFEOA_78 | 5711 | 5457 | spr1327 | 1.01e-45 | essential gene | 95.29 | 100.00 | AAL00131 |
| DMPCFEOA_56 | 58262 | 57999 | spr0175 | 3.43e-42 | pathogenitcity related | 84.09 | 100.00 | AAK98979 |
| DMPCFEOA_56 | 57459 | 57169 | spr0177 | 4.37e-37 | essential gene | 80.00 | 98.02 | AAK98981 |
| DMPCFEOA_24 | 5425 | 4925 | RopE (M5005_Spy_1611) | 1.17e-76 | probable DNA-directed RNA polymerase subunit delta | 81.44 | 87.43 | AAK34603 |
| DMPCFEOA_8 | 28053 | 25756 | PFL (B9H01_RS01125) | 0.0 | formate C-acetyltransferase | 83.07 | 98.08 | MYN69560 |
| DMPCFEOA_34 | 58482 | 57463 | ilvC (SPD_0406) | 0.0 | ketol-acid reductoisomerase (NADP(+)) | 96.47 | 100.00 | ABJ55451 |
BLASTX v2.16.0 (Database: PHI base v4.16, May. 2024 release)
Plasmid
PlasmidFinder
| Query ID | Begin | End | Plasmid | Query / Template | Identity | Accession no. |
|---|---|---|---|---|---|---|
| No hit found | ||||||
PlasmidFinder v 2.1.6 (Database: plasmidfinder_db v 2.2.0 , Nov. 2024 release)
PlasmidHunter
| Query ID | Prediction | Chromosome | Plasmid |
|---|---|---|---|
| DMPCFEOA_1 | 0.0 | 1.0 | 0.0 |
| DMPCFEOA_2 | 0.0 | 1.0 | 0.0 |
| DMPCFEOA_3 | 0.0 | 1.0 | 0.0 |
| DMPCFEOA_4 | 0.0 | 1.0 | 0.0 |
| DMPCFEOA_5 | 0.0 | 1.0 | 0.0 |
| DMPCFEOA_6 | 0.0 | 1.0 | 0.0 |
| DMPCFEOA_7 | 0.0 | 1.0 | 0.0 |
| DMPCFEOA_8 | 0.0 | 1.0 | 0.0 |
| DMPCFEOA_9 | 0.0 | 1.0 | 0.0 |
| DMPCFEOA_10 | 0.0 | 1.0 | 0.0 |
| DMPCFEOA_11 | 0.0 | 1.0 | 0.0 |
| DMPCFEOA_12 | 0.0 | 1.0 | 0.0 |
| DMPCFEOA_13 | 0.0 | 1.0 | 0.0 |
| DMPCFEOA_14 | 0.0 | 1.0 | 0.0 |
| DMPCFEOA_15 | 0.0 | 1.0 | 0.0 |
| DMPCFEOA_16 | 0.0 | 1.0 | 0.0 |
| DMPCFEOA_17 | 0.0 | 1.0 | 0.0 |
| DMPCFEOA_18 | 0.0 | 1.0 | 0.0 |
| DMPCFEOA_19 | 0.0 | 1.0 | 0.0 |
| DMPCFEOA_20 | 0.0 | 1.0 | 0.0 |
| DMPCFEOA_21 | 0.0 | 1.0 | 0.0 |
| DMPCFEOA_22 | 0.0 | 1.0 | 0.0 |
| DMPCFEOA_23 | 0.0 | 1.0 | 0.0 |
| DMPCFEOA_24 | 0.0 | 1.0 | 0.0 |
| DMPCFEOA_25 | 0.0 | 1.0 | 0.0 |
| DMPCFEOA_26 | 0.0 | 1.0 | 0.0 |
| DMPCFEOA_27 | 0.0 | 1.0 | 0.0 |
| DMPCFEOA_28 | 0.0 | 1.0 | 0.0 |
| DMPCFEOA_30 | 0.0 | 1.0 | 0.0 |
| DMPCFEOA_31 | 0.0 | 1.0 | 0.0 |
| DMPCFEOA_32 | 0.0 | 1.0 | 0.0 |
| DMPCFEOA_33 | 0.0 | 1.0 | 0.0 |
| DMPCFEOA_34 | 0.0 | 1.0 | 0.0 |
| DMPCFEOA_35 | 0.0 | 1.0 | 0.0 |
| DMPCFEOA_36 | 1.0 | 0.0 | 1.0 |
| DMPCFEOA_37 | 0.0 | 1.0 | 0.0 |
| DMPCFEOA_38 | 0.0 | 1.0 | 0.0 |
| DMPCFEOA_39 | 0.0 | 1.0 | 0.0 |
| DMPCFEOA_45 | 0.0 | 1.0 | 0.0 |
| DMPCFEOA_56 | 0.0 | 1.0 | 0.0 |
| DMPCFEOA_67 | 0.0 | 1.0 | 0.0 |
| DMPCFEOA_78 | 0.0 | 1.0 | 0.0 |
| DMPCFEOA_89 | 0.0 | 1.0 | 0.0 |
PlasmidHunter v 1.4.5 (Database: May. 2024 release)
Prophage
Phigaro
| Query ID | Begin | End | Transposable | Taxonomy | pVOGs |
|---|---|---|---|---|---|
| No hit found | |||||
Phigaro v2.4.0 (Database: Jan. 2024 release)