Probiotic potential risk score
| ARGs | VFs | PGs | PPRS |
|---|---|---|---|
| 0 | 22 | 32 | 38.83 |
PPRS is classified as low-risk (≤4), medium-risk (4-6), and high-risk (≥6).
Antibiotic resistance genes
Comprehensive Antibiotic Resistance Database (CARD)
| Query ID | Begin | End | ARO name | ARO accession | CARD name | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
RGI v6.0.3 (Database: CARD Variants v4.0.2, Nov. 2023 release)
ResFinder
| Query ID | Begin | End | Resistance gene | Phenotype | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|
| No hit found | |||||||
ResFinder v4.6.0 (Database: resfinder_db, Aug. 2024 release)
AMRFinderPlus
| Query ID | Begin | End | Gene symbol | Sequence name | Method | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
AMRFinderPlus v4.0.3 (Database: Oct. 2024 release)
Virulence factors
Virulence Factor Database (VFDB)
| Query ID | qstart | qend | Gene name | e-value | VF name | VF category | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|---|
| BHDKMDBO_83 | 233 | 1102 | rfbA | 0.0 | Capsule | Immune modulation | 100.00 | 100.00 | WP_011681286 |
| BHDKMDBO_83 | 1102 | 1695 | STER_RS06030 | 0.0 | Capsule | Immune modulation | 100.00 | 100.00 | WP_011226149 |
| BHDKMDBO_78 | 2247 | 3056 | STU_RS16245 | 0.0 | Capsule | Immune modulation | 99.88 | 100.00 | WP_002948020 |
| BHDKMDBO_83 | 1102 | 1695 | STR_RS05880 | 0.0 | Capsule | Immune modulation | 99.83 | 100.00 | WP_011226149 |
| BHDKMDBO_83 | 1102 | 1695 | STU_RS15260 | 0.0 | Capsule | Immune modulation | 99.66 | 100.00 | WP_011226149 |
| BHDKMDBO_130 | 1660 | 3318 | fbp54 | 0.0 | FBPs | Adherence | 99.64 | 100.00 | WP_011227179 |
| BHDKMDBO_78 | 4281 | 5336 | STU_RS16235 | 0.0 | Capsule | Immune modulation | 99.62 | 100.00 | WP_002948022 |
| BHDKMDBO_53 | 20778 | 21617 | cbpD | 0.0 | Autolysin | Exoenzyme | 99.52 | 100.00 | WP_011226733 |
| BHDKMDBO_121 | 1396 | 2127 | STER_RS05315 | 0.0 | Capsule | Immune modulation | 99.32 | 100.00 | WP_011681176 |
| BHDKMDBO_78 | 3056 | 4261 | STU_RS16240 | 0.0 | Capsule | Immune modulation | 99.25 | 100.00 | WP_011226326 |
| BHDKMDBO_78 | 162 | 1310 | STU_RS16255 | 0.0 | Capsule | Immune modulation | 99.22 | 100.00 | WP_041828290 |
| BHDKMDBO_78 | 1307 | 2263 | STU_RS16250 | 0.0 | Capsule | Immune modulation | 99.16 | 100.00 | WP_011226328 |
| BHDKMDBO_78 | 5333 | 7115 | STU_RS16230 | 0.0 | Capsule | Immune modulation | 99.10 | 99.89 | WP_011226325 |
| BHDKMDBO_121 | 1396 | 2127 | STU_RS14645 | 0.0 | Capsule | Immune modulation | 98.77 | 100.00 | WP_011226048 |
| BHDKMDBO_127 | 2978 | 3598 | cshA | 0.0 | Cell surface hydrophobicity proteins | Adherence | 98.71 | 78.51 | - |
| BHDKMDBO_121 | 1396 | 2127 | STR_RS05260 | 0.0 | Capsule | Immune modulation | 98.63 | 100.00 | WP_011227248 |
| BHDKMDBO_121 | 1 | 1395 | STER_RS05320 | 0.0 | Capsule | Immune modulation | 98.21 | 95.48 | WP_011681177 |
| BHDKMDBO_35 | 24426 | 25187 | srtA | 0.0 | Sortase A | Exoenzyme | 97.64 | 100.00 | - |
| BHDKMDBO_121 | 2136 | 2828 | STU_RS14640 | 0.0 | Capsule | Immune modulation | 97.55 | 100.00 | WP_011226047 |
| BHDKMDBO_45 | 24695 | 25546 | rfbD | 0.0 | Capsule | Immune modulation | 97.30 | 100.00 | WP_014621820 |
| BHDKMDBO_121 | 2136 | 2828 | STR_RS05255 | 0.0 | Capsule | Immune modulation | 97.26 | 100.00 | WP_011227247 |
| BHDKMDBO_121 | 2838 | 3578 | STER_RS05305 | 0.0 | Capsule | Immune modulation | 97.03 | 100.00 | WP_011681174 |
| BHDKMDBO_121 | 2838 | 3578 | STU_RS14635 | 0.0 | Capsule | Immune modulation | 96.90 | 100.00 | WP_011226046 |
| BHDKMDBO_121 | 1 | 1395 | STU_RS14650 | 0.0 | Capsule | Immune modulation | 96.85 | 95.67 | WP_011226049 |
| BHDKMDBO_121 | 2838 | 3573 | STR_RS05250 | 0.0 | Capsule | Immune modulation | 96.47 | 98.13 | WP_011227246 |
| BHDKMDBO_121 | 1 | 1395 | STR_RS05265 | 0.0 | Capsule | Immune modulation | 96.13 | 95.67 | WP_041827043 |
| BHDKMDBO_121 | 2136 | 2828 | STER_RS05310 | 0.0 | Capsule | Immune modulation | 90.62 | 100.00 | WP_011681175 |
| BHDKMDBO_114 | 12817 | 14120 | eno | 0.0 | Streptococcal enolase | Exoenzyme | 88.10 | 99.46 | WP_000022832 |
| BHDKMDBO_67 | 14374 | 15384 | plr/gapA | 0.0 | Streptococcal plasmin receptor/GAPDH | Adherence | 87.46 | 99.80 | WP_002986042 |
| BHDKMDBO_70 | 59672 | 60955 | tig/ropA | 0.0 | Trigger factor | Stress survival | 80.73 | 99.77 | WP_000107753 |
| BHDKMDBO_83 | 2124 | 3170 | rfbB | 0.0 | Capsule | Immune modulation | 80.61 | 100.00 | WP_009659423 |
| BHDKMDBO_96 | 6521 | 7104 | SPD_RS01775 | 4.90e-149 | Capsule | Immune modulation | 83.08 | 96.20 | WP_001819836 |
| BHDKMDBO_121 | 3635 | 4491 | STU_RS14630 | 0.0 | Capsule | Immune modulation | 96.85 | 62.57 | WP_011226045 |
| BHDKMDBO_121 | 3635 | 4491 | STER_RS05300 | 0.0 | Capsule | Immune modulation | 95.22 | 62.57 | WP_011681173 |
BLASTN v2.16.0 (Database: VFDB, Dec. 2024 release)
VirulenceFinder
| Query ID | Begin | End | Database | Virulence factor | Protein function | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
VirulenceFinder v2.0. 4 (Database: virulencefinder_db, Feb . 2024 release)
Pathogenic genes
PHI-base
| Query ID | qstart | qend | Gene name | e-value | Function | Identity | Coverage | Gene ID |
|---|---|---|---|---|---|---|---|---|
| BHDKMDBO_35 | 21739 | 20756 | ldh(Sp_1220) | 0.0 | L-lactate dehydrogenase | 94.82 | 100.00 | AAK75326 |
| BHDKMDBO_69 | 5415 | 6488 | MntE | 0.0 | manganese homeostasis | 94.41 | 99.72 | ABF32167 |
| BHDKMDBO_1 | 75913 | 78216 | pfl2(Sp_0459) | 0.0 | formate acetyltransferase | 92.97 | 99.22 | AAK74619 |
| BHDKMDBO_62 | 10048 | 9080 | spr0084 | 0.0 | pathogenitcity related | 92.57 | 98.48 | AAK98888 |
| BHDKMDBO_103 | 8475 | 6994 | SPD_0310 | 0.0 | UPF0371 protein SPD_0310 | 92.31 | 100.00 | ABJ54480 |
| BHDKMDBO_95 | 6022 | 8268 | metE | 0.0 | methionine biosynthesis enzymes | 91.99 | 100.00 | AAK74738 |
| BHDKMDBO_53 | 1986 | 988 | recA | 0.0 | DNA recombination and repair | 91.29 | 85.82 | AAL00560 |
| BHDKMDBO_57 | 15363 | 14392 | prsA2 | 0.0 | ribose-phosphate pyrophosphokinase | 90.12 | 100.00 | ABF36968 |
| BHDKMDBO_48 | 23732 | 22581 | potA | 0.0 | ABC transporter ATP-binding protein-spermidine/putrescine transport | 89.32 | 99.74 | AAL00050 |
| BHDKMDBO_45 | 11523 | 13511 | uvrB | 0.0 | excinuclease ABC, B subunit | 88.99 | 100.00 | AE014259_2 |
| BHDKMDBO_43 | 7376 | 9106 | ptsI | 0.0 | phosphoenolpyruvate-protein phosphotransferase | 88.39 | 100.00 | AAK34199 |
| BHDKMDBO_64 | 2807 | 1329 | IMPDH | 0.0 | inosine-5'-monophosphate dehydrogenase | 87.63 | 100.00 | ADE32434 |
| BHDKMDBO_114 | 12817 | 14118 | Eno | 0.0 | enolase | 86.21 | 99.77 | ABP90468 |
| BHDKMDBO_49 | 12070 | 10178 | gidA | 0.0 | tRNA uridine 5-carboxymethylaminomethyl modification enzyme | 85.74 | 98.90 | ABP91129 |
| BHDKMDBO_89 | 6122 | 7831 | PGM | 0.0 | phosphoglucomutase | 84.06 | 99.65 | ACH87041 |
| BHDKMDBO_54 | 19074 | 20084 | pdh | 0.0 | pyruvate dehydrogenase | 83.09 | 99.70 | ABP91006 |
| BHDKMDBO_92 | 48400 | 46508 | PepO | 0.0 | endopeptidase | 80.19 | 100.00 | ABF32980 |
| BHDKMDBO_42 | 1635 | 745 | bglB | 2.07e-180 | putative phospho--glucosidase | 88.89 | 99.66 | AAK33487 |
| BHDKMDBO_113 | 1422 | 484 | SP_0676 | 1.97e-172 | transcription facot | 81.15 | 97.20 | AAK74821 |
| BHDKMDBO_89 | 8753 | 7998 | metF | 2.04e-149 | methionine biosynthesis enzymes | 88.09 | 87.50 | AAK74739 |
| BHDKMDBO_2 | 24814 | 25518 | covR | 7.93e-133 | responder protein | 85.53 | 100.00 | AAK71319 |
| BHDKMDBO_103 | 27455 | 28126 | rr01 | 7.62e-126 | response regulator | 83.93 | 99.56 | CAB54566 |
| BHDKMDBO_89 | 2167 | 1499 | CiaR | 3.93e-125 | two-component response regulator | 86.10 | 99.55 | AAK74935 |
| BHDKMDBO_2 | 24814 | 25518 | walR | 3.34e-123 | DNA-binding response regulator | 82.13 | 100.00 | ANC99504 |
| BHDKMDBO_89 | 2167 | 1496 | ciaR | 5.33e-123 | two component system response regulator | 83.93 | 99.12 | AIK75708 |
| BHDKMDBO_47 | 16345 | 17031 | CovR | 3.95e-120 | serves to repress GAS virulence factor-encoding genes | 81.22 | 100.00 | ACE75886 |
| BHDKMDBO_53 | 712 | 338 | SpxA2 | 1.37e-71 | transcriptional regulator | 91.20 | 94.70 | ERL21461 |
| BHDKMDBO_66 | 7096 | 6695 | SpxA1 | 3.23e-68 | transcriptional regulator | 80.60 | 100.00 | ERL19273 |
| BHDKMDBO_60 | 4058 | 3771 | spr0479 | 1.37e-49 | essential gene | 86.46 | 98.97 | AAK99283 |
| BHDKMDBO_81 | 47954 | 48208 | spr1327 | 8.61e-46 | essential gene | 95.29 | 100.00 | AAL00131 |
| BHDKMDBO_125 | 22068 | 21805 | spr0175 | 1.45e-42 | pathogenitcity related | 84.09 | 100.00 | AAK98979 |
| BHDKMDBO_125 | 21241 | 20975 | spr0177 | 3.16e-34 | essential gene | 84.27 | 88.12 | AAK98981 |
| BHDKMDBO_70 | 59514 | 59014 | RopE (M5005_Spy_1611) | 1.67e-76 | probable DNA-directed RNA polymerase subunit delta | 81.44 | 87.43 | AAK34603 |
| BHDKMDBO_1 | 75913 | 78210 | PFL (B9H01_RS01125) | 0.0 | formate C-acetyltransferase | 82.94 | 98.08 | MYN69560 |
| BHDKMDBO_92 | 33941 | 32922 | ilvC (SPD_0406) | 0.0 | ketol-acid reductoisomerase (NADP(+)) | 96.47 | 100.00 | ABJ55451 |
| BHDKMDBO_68 | 2 | 937 | mnmE | 5.96e-157 | central tRNA-modifying GTPase | 83.01 | 68.27 | ABP90420 |
BLASTX v2.16.0 (Database: PHI base v4.16, May. 2024 release)
Plasmid
PlasmidFinder
| Query ID | Begin | End | Plasmid | Query / Template | Identity | Accession no. |
|---|---|---|---|---|---|---|
| No hit found | ||||||
PlasmidFinder v 2.1.6 (Database: plasmidfinder_db v 2.2.0 , Nov. 2024 release)
PlasmidHunter
| Query ID | Prediction | Chromosome | Plasmid |
|---|---|---|---|
| BHDKMDBO_1 | 0.0 | 1.0 | 0.0 |
| BHDKMDBO_2 | 0.0 | 1.0 | 0.0 |
| BHDKMDBO_3 | 0.0 | 1.0 | 0.0 |
| BHDKMDBO_4 | 0.0 | 1.0 | 0.0 |
| BHDKMDBO_5 | 0.0 | 1.0 | 0.0 |
| BHDKMDBO_6 | 0.0 | 1.0 | 0.0 |
| BHDKMDBO_7 | 0.0 | 1.0 | 0.0 |
| BHDKMDBO_8 | 0.0 | 1.0 | 0.0 |
| BHDKMDBO_10 | 0.0 | 1.0 | 0.0 |
| BHDKMDBO_11 | 0.0 | 1.0 | 0.0 |
| BHDKMDBO_12 | 0.0 | 1.0 | 0.0 |
| BHDKMDBO_13 | 0.0 | 1.0 | 0.0 |
| BHDKMDBO_14 | 0.0 | 1.0 | 0.0 |
| BHDKMDBO_15 | 1.0 | 0.0 | 1.0 |
| BHDKMDBO_16 | 0.0 | 1.0 | 0.0 |
| BHDKMDBO_17 | 0.0 | 1.0 | 0.0 |
| BHDKMDBO_18 | 0.0 | 1.0 | 0.0 |
| BHDKMDBO_20 | 0.0 | 1.0 | 0.0 |
| BHDKMDBO_21 | 0.0 | 1.0 | 0.0 |
| BHDKMDBO_22 | 0.0 | 1.0 | 0.0 |
| BHDKMDBO_23 | 1.0 | 0.0 | 1.0 |
| BHDKMDBO_24 | 0.0 | 1.0 | 0.0 |
| BHDKMDBO_25 | 0.0 | 1.0 | 0.0 |
| BHDKMDBO_26 | 0.0 | 1.0 | 0.0 |
| BHDKMDBO_27 | 0.0 | 1.0 | 0.0 |
| BHDKMDBO_28 | 0.0 | 1.0 | 0.0 |
| BHDKMDBO_29 | 0.0 | 1.0 | 0.0 |
| BHDKMDBO_30 | 0.0 | 1.0 | 0.0 |
| BHDKMDBO_31 | 0.0 | 1.0 | 0.0 |
| BHDKMDBO_32 | 0.0 | 1.0 | 0.0 |
| BHDKMDBO_33 | 0.0 | 1.0 | 0.0 |
| BHDKMDBO_34 | 0.0 | 1.0 | 0.0 |
| BHDKMDBO_35 | 0.0 | 1.0 | 0.0 |
| BHDKMDBO_36 | 1.0 | 0.0 | 1.0 |
| BHDKMDBO_37 | 0.0 | 1.0 | 0.0 |
| BHDKMDBO_38 | 0.0 | 1.0 | 0.0 |
| BHDKMDBO_39 | 0.0 | 1.0 | 0.0 |
| BHDKMDBO_42 | 0.0 | 1.0 | 0.0 |
| BHDKMDBO_43 | 0.0 | 1.0 | 0.0 |
| BHDKMDBO_44 | 0.0 | 1.0 | 0.0 |
| BHDKMDBO_45 | 0.0 | 1.0 | 0.0 |
| BHDKMDBO_46 | 0.0 | 1.0 | 0.0 |
| BHDKMDBO_47 | 0.0 | 1.0 | 0.0 |
| BHDKMDBO_48 | 0.0 | 1.0 | 0.0 |
| BHDKMDBO_49 | 0.0 | 1.0 | 0.0 |
| BHDKMDBO_50 | 0.0 | 1.0 | 0.0 |
| BHDKMDBO_51 | 0.0 | 1.0 | 0.0 |
| BHDKMDBO_52 | 0.0 | 1.0 | 0.0 |
| BHDKMDBO_53 | 0.0 | 1.0 | 0.0 |
| BHDKMDBO_54 | 0.0 | 1.0 | 0.0 |
| BHDKMDBO_55 | 0.0 | 1.0 | 0.0 |
| BHDKMDBO_56 | 0.0 | 1.0 | 0.0 |
| BHDKMDBO_57 | 0.0 | 1.0 | 0.0 |
| BHDKMDBO_58 | 0.0 | 1.0 | 0.0 |
| BHDKMDBO_59 | 0.0 | 1.0 | 0.0 |
| BHDKMDBO_60 | 0.0 | 1.0 | 0.0 |
| BHDKMDBO_61 | 0.0 | 1.0 | 0.0 |
| BHDKMDBO_62 | 0.0 | 1.0 | 0.0 |
| BHDKMDBO_63 | 0.0 | 1.0 | 0.0 |
| BHDKMDBO_64 | 0.0 | 1.0 | 0.0 |
| BHDKMDBO_65 | 0.0 | 1.0 | 0.0 |
| BHDKMDBO_66 | 0.0 | 1.0 | 0.0 |
| BHDKMDBO_67 | 0.0 | 1.0 | 0.0 |
| BHDKMDBO_68 | 0.0 | 1.0 | 0.0 |
| BHDKMDBO_69 | 0.0 | 1.0 | 0.0 |
| BHDKMDBO_70 | 0.0 | 1.0 | 0.0 |
| BHDKMDBO_71 | 0.0 | 1.0 | 0.0 |
| BHDKMDBO_72 | 0.0 | 1.0 | 0.0 |
| BHDKMDBO_73 | 0.0 | 1.0 | 0.0 |
| BHDKMDBO_74 | 0.0 | 1.0 | 0.0 |
| BHDKMDBO_75 | 0.0 | 1.0 | 0.0 |
| BHDKMDBO_76 | 0.0 | 1.0 | 0.0 |
| BHDKMDBO_77 | 0.0 | 1.0 | 0.0 |
| BHDKMDBO_78 | 0.0 | 1.0 | 0.0 |
| BHDKMDBO_79 | 0.0 | 1.0 | 0.0 |
| BHDKMDBO_80 | 0.0 | 1.0 | 0.0 |
| BHDKMDBO_81 | 0.0 | 1.0 | 0.0 |
| BHDKMDBO_82 | 0.0 | 1.0 | 0.0 |
| BHDKMDBO_83 | 0.0 | 1.0 | 0.0 |
| BHDKMDBO_84 | 0.0 | 1.0 | 0.0 |
| BHDKMDBO_85 | 0.0 | 1.0 | 0.0 |
| BHDKMDBO_86 | 0.0 | 1.0 | 0.0 |
| BHDKMDBO_87 | 0.0 | 1.0 | 0.0 |
| BHDKMDBO_88 | 0.0 | 1.0 | 0.0 |
| BHDKMDBO_89 | 0.0 | 1.0 | 0.0 |
| BHDKMDBO_90 | 0.0 | 1.0 | 0.0 |
| BHDKMDBO_91 | 0.0 | 1.0 | 0.0 |
| BHDKMDBO_92 | 0.0 | 1.0 | 0.0 |
| BHDKMDBO_93 | 0.0 | 1.0 | 0.0 |
| BHDKMDBO_94 | 0.0 | 1.0 | 0.0 |
| BHDKMDBO_95 | 0.0 | 1.0 | 0.0 |
| BHDKMDBO_96 | 0.0 | 1.0 | 0.0 |
| BHDKMDBO_97 | 0.0 | 1.0 | 0.0 |
| BHDKMDBO_98 | 0.0 | 1.0 | 0.0 |
| BHDKMDBO_99 | 0.0 | 1.0 | 0.0 |
| BHDKMDBO_100 | 0.0 | 1.0 | 0.0 |
| BHDKMDBO_101 | 0.0 | 1.0 | 0.0 |
| BHDKMDBO_102 | 0.0 | 1.0 | 0.0 |
| BHDKMDBO_103 | 0.0 | 1.0 | 0.0 |
| BHDKMDBO_104 | 1.0 | 0.0 | 1.0 |
| BHDKMDBO_105 | 0.0 | 1.0 | 0.0 |
| BHDKMDBO_106 | 0.0 | 1.0 | 0.0 |
| BHDKMDBO_107 | 0.0 | 1.0 | 0.0 |
| BHDKMDBO_108 | 0.0 | 1.0 | 0.0 |
| BHDKMDBO_109 | 0.0 | 1.0 | 0.0 |
| BHDKMDBO_110 | 0.0 | 1.0 | 0.0 |
| BHDKMDBO_111 | 0.0 | 1.0 | 0.0 |
| BHDKMDBO_112 | 0.0 | 1.0 | 0.0 |
| BHDKMDBO_113 | 0.0 | 1.0 | 0.0 |
| BHDKMDBO_114 | 0.0 | 1.0 | 0.0 |
| BHDKMDBO_115 | 0.0 | 1.0 | 0.0 |
| BHDKMDBO_116 | 1.0 | 0.0 | 1.0 |
| BHDKMDBO_117 | 0.0 | 1.0 | 0.0 |
| BHDKMDBO_118 | 0.0 | 1.0 | 0.0 |
| BHDKMDBO_119 | 0.0 | 1.0 | 0.0 |
| BHDKMDBO_120 | 0.0 | 1.0 | 0.0 |
| BHDKMDBO_121 | 0.0 | 1.0 | 0.0 |
| BHDKMDBO_122 | 0.0 | 1.0 | 0.0 |
| BHDKMDBO_123 | 0.0 | 1.0 | 0.0 |
| BHDKMDBO_124 | 0.0 | 1.0 | 0.0 |
| BHDKMDBO_125 | 0.0 | 1.0 | 0.0 |
| BHDKMDBO_126 | 0.0 | 1.0 | 0.0 |
| BHDKMDBO_127 | 0.0 | 1.0 | 0.0 |
| BHDKMDBO_128 | 1.0 | 0.0 | 1.0 |
| BHDKMDBO_129 | 0.0 | 1.0 | 0.0 |
| BHDKMDBO_130 | 1.0 | 0.0 | 1.0 |
| BHDKMDBO_131 | 0.0 | 1.0 | 0.0 |
| BHDKMDBO_132 | 0.0 | 1.0 | 0.0 |
| BHDKMDBO_133 | 0.0 | 1.0 | 0.0 |
| BHDKMDBO_134 | 0.0 | 1.0 | 0.0 |
| BHDKMDBO_135 | 0.0 | 1.0 | 0.0 |
PlasmidHunter v 1.4.5 (Database: May. 2024 release)
Prophage
Phigaro
| Query ID | Begin | End | Transposable | Taxonomy | pVOGs |
|---|---|---|---|---|---|
| No hit found | |||||
Phigaro v2.4.0 (Database: Jan. 2024 release)