Probiotic potential risk score
| ARGs | VFs | PGs | PPRS |
|---|---|---|---|
| 0 | 21 | 33 | 39.12 |
PPRS is classified as low-risk (≤4), medium-risk (4-6), and high-risk (≥6).
Antibiotic resistance genes
Comprehensive Antibiotic Resistance Database (CARD)
| Query ID | Begin | End | ARO name | ARO accession | CARD name | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
RGI v6.0.3 (Database: CARD Variants v4.0.2, Nov. 2023 release)
ResFinder
| Query ID | Begin | End | Resistance gene | Phenotype | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|
| No hit found | |||||||
ResFinder v4.6.0 (Database: resfinder_db, Aug. 2024 release)
AMRFinderPlus
| Query ID | Begin | End | Gene symbol | Sequence name | Method | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
AMRFinderPlus v4.0.3 (Database: Oct. 2024 release)
Virulence factors
Virulence Factor Database (VFDB)
| Query ID | qstart | qend | Gene name | e-value | VF name | VF category | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|---|
| KPOFCINO_54 | 414 | 1283 | rfbA | 0.0 | Capsule | Immune modulation | 100.00 | 100.00 | WP_011681286 |
| KPOFCINO_53 | 9348 | 10157 | STU_RS16245 | 0.0 | Capsule | Immune modulation | 99.88 | 100.00 | WP_002948020 |
| KPOFCINO_70 | 5132 | 6790 | fbp54 | 0.0 | FBPs | Adherence | 99.64 | 100.00 | WP_011227179 |
| KPOFCINO_53 | 7068 | 8123 | STU_RS16235 | 0.0 | Capsule | Immune modulation | 99.62 | 100.00 | WP_002948022 |
| KPOFCINO_86 | 3669 | 4400 | STER_RS05315 | 0.0 | Capsule | Immune modulation | 99.32 | 100.00 | WP_011681176 |
| KPOFCINO_53 | 8143 | 9348 | STU_RS16240 | 0.0 | Capsule | Immune modulation | 99.25 | 100.00 | WP_011226326 |
| KPOFCINO_53 | 11094 | 12242 | STU_RS16255 | 0.0 | Capsule | Immune modulation | 99.22 | 100.00 | WP_041828290 |
| KPOFCINO_53 | 10141 | 11097 | STU_RS16250 | 0.0 | Capsule | Immune modulation | 99.16 | 100.00 | WP_011226328 |
| KPOFCINO_53 | 5289 | 7071 | STU_RS16230 | 0.0 | Capsule | Immune modulation | 99.10 | 99.89 | WP_011226325 |
| KPOFCINO_2 | 16339 | 17307 | cbpD | 0.0 | Autolysin | Exoenzyme | 98.86 | 100.00 | WP_082302295 |
| KPOFCINO_86 | 3669 | 4400 | STU_RS14645 | 0.0 | Capsule | Immune modulation | 98.77 | 100.00 | WP_011226048 |
| KPOFCINO_86 | 3669 | 4400 | STR_RS05260 | 0.0 | Capsule | Immune modulation | 98.63 | 100.00 | WP_011227248 |
| KPOFCINO_86 | 4401 | 5861 | STER_RS05320 | 0.0 | Capsule | Immune modulation | 98.29 | 100.00 | WP_011681177 |
| KPOFCINO_93 | 25798 | 26559 | srtA | 0.0 | Sortase A | Exoenzyme | 97.64 | 100.00 | - |
| KPOFCINO_86 | 2968 | 3660 | STU_RS14640 | 0.0 | Capsule | Immune modulation | 97.55 | 100.00 | WP_011226047 |
| KPOFCINO_30 | 333 | 1184 | rfbD | 0.0 | Capsule | Immune modulation | 97.30 | 100.00 | WP_014621820 |
| KPOFCINO_86 | 2968 | 3660 | STR_RS05255 | 0.0 | Capsule | Immune modulation | 97.26 | 100.00 | WP_011227247 |
| KPOFCINO_86 | 2218 | 2958 | STER_RS05305 | 0.0 | Capsule | Immune modulation | 97.03 | 100.00 | WP_011681174 |
| KPOFCINO_86 | 2218 | 2958 | STU_RS14635 | 0.0 | Capsule | Immune modulation | 96.90 | 100.00 | WP_011226046 |
| KPOFCINO_86 | 4401 | 5861 | STU_RS14650 | 0.0 | Capsule | Immune modulation | 96.85 | 100.21 | WP_011226049 |
| KPOFCINO_86 | 2223 | 2958 | STR_RS05250 | 0.0 | Capsule | Immune modulation | 96.47 | 98.13 | WP_011227246 |
| KPOFCINO_86 | 4401 | 5861 | STR_RS05265 | 0.0 | Capsule | Immune modulation | 95.89 | 100.21 | WP_041827043 |
| KPOFCINO_86 | 794 | 2161 | STU_RS14630 | 0.0 | Capsule | Immune modulation | 95.11 | 99.93 | WP_011226045 |
| KPOFCINO_86 | 796 | 2161 | STER_RS05300 | 0.0 | Capsule | Immune modulation | 94.66 | 99.78 | WP_011681173 |
| KPOFCINO_86 | 2968 | 3660 | STER_RS05310 | 0.0 | Capsule | Immune modulation | 90.62 | 100.00 | WP_011681175 |
| KPOFCINO_38 | 10222 | 11525 | eno | 0.0 | Streptococcal enolase | Exoenzyme | 88.10 | 99.46 | WP_000022832 |
| KPOFCINO_42 | 139 | 1149 | plr/gapA | 0.0 | Streptococcal plasmin receptor/GAPDH | Adherence | 87.46 | 99.80 | WP_002986042 |
| KPOFCINO_81 | 2232 | 3515 | tig/ropA | 0.0 | Trigger factor | Stress survival | 80.73 | 99.77 | WP_000107753 |
| KPOFCINO_66 | 619 | 1665 | rfbB | 0.0 | Capsule | Immune modulation | 80.61 | 100.00 | WP_009659423 |
| KPOFCINO_69 | 1185 | 1768 | SPD_RS01775 | 4.90e-149 | Capsule | Immune modulation | 83.08 | 96.20 | WP_001819836 |
| KPOFCINO_54 | 1 | 414 | STER_RS06030 | 0.0 | Capsule | Immune modulation | 100.00 | 69.70 | WP_011226149 |
| KPOFCINO_54 | 1 | 414 | STR_RS05880 | 0.0 | Capsule | Immune modulation | 100.00 | 69.70 | WP_011226149 |
| KPOFCINO_54 | 1 | 414 | STU_RS15260 | 0.0 | Capsule | Immune modulation | 100.00 | 69.70 | WP_011226149 |
| KPOFCINO_3 | 1 | 542 | cshA | 0.0 | Cell surface hydrophobicity proteins | Adherence | 98.52 | 68.39 | - |
BLASTN v2.16.0 (Database: VFDB, Dec. 2024 release)
VirulenceFinder
| Query ID | Begin | End | Database | Virulence factor | Protein function | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
VirulenceFinder v2.0. 4 (Database: virulencefinder_db, Feb . 2024 release)
Pathogenic genes
PHI-base
| Query ID | qstart | qend | Gene name | e-value | Function | Identity | Coverage | Gene ID |
|---|---|---|---|---|---|---|---|---|
| KPOFCINO_93 | 23111 | 22128 | ldh(Sp_1220) | 0.0 | L-lactate dehydrogenase | 94.82 | 100.00 | AAK75326 |
| KPOFCINO_35 | 10262 | 9189 | MntE | 0.0 | manganese homeostasis | 94.41 | 99.72 | ABF32167 |
| KPOFCINO_1 | 137382 | 139685 | pfl2(Sp_0459) | 0.0 | formate acetyltransferase | 92.97 | 99.22 | AAK74619 |
| KPOFCINO_49 | 29580 | 28612 | spr0084 | 0.0 | pathogenitcity related | 92.57 | 98.48 | AAK98888 |
| KPOFCINO_60 | 48616 | 47135 | SPD_0310 | 0.0 | UPF0371 protein SPD_0310 | 92.31 | 100.00 | ABJ54480 |
| KPOFCINO_43 | 4099 | 6345 | metE | 0.0 | methionine biosynthesis enzymes | 91.99 | 100.00 | AAK74738 |
| KPOFCINO_31 | 20233 | 21231 | recA | 0.0 | DNA recombination and repair | 91.29 | 85.82 | AAL00560 |
| KPOFCINO_41 | 1 | 957 | prsA2 | 0.0 | ribose-phosphate pyrophosphokinase | 90.60 | 98.46 | ABF36968 |
| KPOFCINO_1 | 16161 | 15010 | potA | 0.0 | ABC transporter ATP-binding protein-spermidine/putrescine transport | 89.32 | 99.74 | AAL00050 |
| KPOFCINO_30 | 14356 | 12368 | uvrB | 0.0 | excinuclease ABC, B subunit | 88.99 | 100.00 | AE014259_2 |
| KPOFCINO_57 | 10383 | 8653 | ptsI | 0.0 | phosphoenolpyruvate-protein phosphotransferase | 88.39 | 100.00 | AAK34199 |
| KPOFCINO_37 | 14098 | 15576 | IMPDH | 0.0 | inosine-5'-monophosphate dehydrogenase | 87.63 | 100.00 | ADE32434 |
| KPOFCINO_38 | 11525 | 10224 | Eno | 0.0 | enolase | 86.21 | 99.77 | ABP90468 |
| KPOFCINO_28 | 11878 | 13770 | gidA | 0.0 | tRNA uridine 5-carboxymethylaminomethyl modification enzyme | 85.74 | 98.90 | ABP91129 |
| KPOFCINO_94 | 4400 | 3249 | mnmE | 0.0 | central tRNA-modifying GTPase | 84.64 | 84.03 | ABP90420 |
| KPOFCINO_43 | 9270 | 7561 | PGM | 0.0 | phosphoglucomutase | 84.06 | 99.65 | ACH87041 |
| KPOFCINO_32 | 2031 | 1021 | pdh | 0.0 | pyruvate dehydrogenase | 83.09 | 99.70 | ABP91006 |
| KPOFCINO_71 | 48400 | 46508 | PepO | 0.0 | endopeptidase | 80.19 | 100.00 | ABF32980 |
| KPOFCINO_38 | 25961 | 25071 | bglB | 4.57e-180 | putative phospho--glucosidase | 88.89 | 99.66 | AAK33487 |
| KPOFCINO_46 | 12541 | 13479 | SP_0676 | 1.72e-169 | transcription facot | 81.15 | 97.20 | AAK74821 |
| KPOFCINO_43 | 6537 | 7394 | metF | 2.04e-166 | methionine biosynthesis enzymes | 86.01 | 99.31 | AAK74739 |
| KPOFCINO_22 | 2966 | 2262 | covR | 2.47e-132 | responder protein | 85.11 | 100.00 | AAK71319 |
| KPOFCINO_13 | 25043 | 24372 | rr01 | 5.63e-126 | response regulator | 83.93 | 99.56 | CAB54566 |
| KPOFCINO_43 | 13225 | 13893 | CiaR | 7.06e-125 | two-component response regulator | 86.10 | 99.55 | AAK74935 |
| KPOFCINO_22 | 2966 | 2262 | walR | 8.49e-123 | DNA-binding response regulator | 81.70 | 100.00 | ANC99504 |
| KPOFCINO_43 | 13225 | 13896 | ciaR | 9.56e-123 | two component system response regulator | 83.93 | 99.12 | AIK75708 |
| KPOFCINO_25 | 8020 | 7334 | CovR | 4.03e-120 | serves to repress GAS virulence factor-encoding genes | 81.22 | 100.00 | ACE75886 |
| KPOFCINO_31 | 21507 | 21881 | SpxA2 | 1.37e-71 | transcriptional regulator | 91.20 | 94.70 | ERL21461 |
| KPOFCINO_34 | 292 | 693 | SpxA1 | 3.56e-68 | transcriptional regulator | 80.60 | 100.00 | ERL19273 |
| KPOFCINO_45 | 13893 | 14180 | spr0479 | 1.12e-49 | essential gene | 86.46 | 98.97 | AAK99283 |
| KPOFCINO_19 | 24547 | 24801 | spr1327 | 5.12e-46 | essential gene | 95.29 | 100.00 | AAL00131 |
| KPOFCINO_104 | 15505 | 15768 | spr0175 | 1.45e-42 | pathogenitcity related | 84.09 | 100.00 | AAK98979 |
| KPOFCINO_104 | 16332 | 16598 | spr0177 | 3.16e-34 | essential gene | 84.27 | 88.12 | AAK98981 |
| KPOFCINO_81 | 3673 | 4173 | RopE (M5005_Spy_1611) | 1.77e-77 | probable DNA-directed RNA polymerase subunit delta | 81.44 | 87.43 | AAK34603 |
| KPOFCINO_1 | 137382 | 139679 | PFL (B9H01_RS01125) | 0.0 | formate C-acetyltransferase | 82.94 | 98.08 | MYN69560 |
| KPOFCINO_71 | 33941 | 32922 | ilvC (SPD_0406) | 0.0 | ketol-acid reductoisomerase (NADP(+)) | 96.47 | 100.00 | ABJ55451 |
BLASTX v2.16.0 (Database: PHI base v4.16, May. 2024 release)
Plasmid
PlasmidFinder
| Query ID | Begin | End | Plasmid | Query / Template | Identity | Accession no. |
|---|---|---|---|---|---|---|
| No hit found | ||||||
PlasmidFinder v 2.1.6 (Database: plasmidfinder_db v 2.2.0 , Nov. 2024 release)
PlasmidHunter
| Query ID | Prediction | Chromosome | Plasmid |
|---|---|---|---|
| KPOFCINO_1 | 0.0 | 1.0 | 0.0 |
| KPOFCINO_2 | 0.0 | 1.0 | 0.0 |
| KPOFCINO_3 | 0.0 | 1.0 | 0.0 |
| KPOFCINO_4 | 0.0 | 1.0 | 0.0 |
| KPOFCINO_5 | 0.0 | 1.0 | 0.0 |
| KPOFCINO_6 | 0.0 | 1.0 | 0.0 |
| KPOFCINO_7 | 0.0 | 1.0 | 0.0 |
| KPOFCINO_8 | 0.0 | 1.0 | 0.0 |
| KPOFCINO_9 | 0.0 | 1.0 | 0.0 |
| KPOFCINO_10 | 0.0 | 1.0 | 0.0 |
| KPOFCINO_11 | 1.0 | 0.0 | 1.0 |
| KPOFCINO_12 | 1.0 | 0.0 | 1.0 |
| KPOFCINO_13 | 0.0 | 1.0 | 0.0 |
| KPOFCINO_15 | 0.0 | 1.0 | 0.0 |
| KPOFCINO_16 | 0.0 | 1.0 | 0.0 |
| KPOFCINO_17 | 0.0 | 1.0 | 0.0 |
| KPOFCINO_19 | 0.0 | 1.0 | 0.0 |
| KPOFCINO_20 | 0.0 | 1.0 | 0.0 |
| KPOFCINO_21 | 0.0 | 1.0 | 0.0 |
| KPOFCINO_22 | 0.0 | 1.0 | 0.0 |
| KPOFCINO_23 | 0.0 | 1.0 | 0.0 |
| KPOFCINO_24 | 0.0 | 1.0 | 0.0 |
| KPOFCINO_25 | 0.0 | 1.0 | 0.0 |
| KPOFCINO_26 | 0.0 | 1.0 | 0.0 |
| KPOFCINO_27 | 0.0 | 1.0 | 0.0 |
| KPOFCINO_28 | 0.0 | 1.0 | 0.0 |
| KPOFCINO_29 | 0.0 | 1.0 | 0.0 |
| KPOFCINO_30 | 0.0 | 1.0 | 0.0 |
| KPOFCINO_31 | 0.0 | 1.0 | 0.0 |
| KPOFCINO_32 | 0.0 | 1.0 | 0.0 |
| KPOFCINO_33 | 0.0 | 1.0 | 0.0 |
| KPOFCINO_34 | 0.0 | 1.0 | 0.0 |
| KPOFCINO_35 | 0.0 | 1.0 | 0.0 |
| KPOFCINO_36 | 0.0 | 1.0 | 0.0 |
| KPOFCINO_37 | 0.0 | 1.0 | 0.0 |
| KPOFCINO_38 | 0.0 | 1.0 | 0.0 |
| KPOFCINO_39 | 0.0 | 1.0 | 0.0 |
| KPOFCINO_40 | 0.0 | 1.0 | 0.0 |
| KPOFCINO_41 | 0.0 | 1.0 | 0.0 |
| KPOFCINO_42 | 0.0 | 1.0 | 0.0 |
| KPOFCINO_43 | 0.0 | 1.0 | 0.0 |
| KPOFCINO_44 | 0.0 | 1.0 | 0.0 |
| KPOFCINO_45 | 0.0 | 1.0 | 0.0 |
| KPOFCINO_46 | 0.0 | 1.0 | 0.0 |
| KPOFCINO_47 | 0.0 | 1.0 | 0.0 |
| KPOFCINO_48 | 0.0 | 1.0 | 0.0 |
| KPOFCINO_49 | 0.0 | 1.0 | 0.0 |
| KPOFCINO_50 | 0.0 | 1.0 | 0.0 |
| KPOFCINO_51 | 0.0 | 1.0 | 0.0 |
| KPOFCINO_52 | 0.0 | 1.0 | 0.0 |
| KPOFCINO_53 | 0.0 | 1.0 | 0.0 |
| KPOFCINO_54 | 0.0 | 1.0 | 0.0 |
| KPOFCINO_55 | 0.0 | 1.0 | 0.0 |
| KPOFCINO_56 | 0.0 | 1.0 | 0.0 |
| KPOFCINO_57 | 0.0 | 1.0 | 0.0 |
| KPOFCINO_58 | 0.0 | 1.0 | 0.0 |
| KPOFCINO_59 | 0.0 | 1.0 | 0.0 |
| KPOFCINO_60 | 0.0 | 1.0 | 0.0 |
| KPOFCINO_61 | 0.0 | 1.0 | 0.0 |
| KPOFCINO_62 | 0.0 | 1.0 | 0.0 |
| KPOFCINO_63 | 0.0 | 1.0 | 0.0 |
| KPOFCINO_64 | 0.0 | 1.0 | 0.0 |
| KPOFCINO_65 | 0.0 | 1.0 | 0.0 |
| KPOFCINO_66 | 0.0 | 1.0 | 0.0 |
| KPOFCINO_67 | 0.0 | 1.0 | 0.0 |
| KPOFCINO_68 | 0.0 | 1.0 | 0.0 |
| KPOFCINO_69 | 0.0 | 1.0 | 0.0 |
| KPOFCINO_70 | 0.0 | 1.0 | 0.0 |
| KPOFCINO_71 | 0.0 | 1.0 | 0.0 |
| KPOFCINO_72 | 0.0 | 1.0 | 0.0 |
| KPOFCINO_73 | 0.0 | 1.0 | 0.0 |
| KPOFCINO_74 | 0.0 | 1.0 | 0.0 |
| KPOFCINO_75 | 0.0 | 1.0 | 0.0 |
| KPOFCINO_76 | 0.0 | 1.0 | 0.0 |
| KPOFCINO_77 | 0.0 | 1.0 | 0.0 |
| KPOFCINO_78 | 0.0 | 1.0 | 0.0 |
| KPOFCINO_79 | 0.0 | 1.0 | 0.0 |
| KPOFCINO_80 | 1.0 | 0.0 | 1.0 |
| KPOFCINO_81 | 0.0 | 1.0 | 0.0 |
| KPOFCINO_82 | 0.0 | 1.0 | 0.0 |
| KPOFCINO_83 | 0.0 | 1.0 | 0.0 |
| KPOFCINO_84 | 0.0 | 1.0 | 0.0 |
| KPOFCINO_85 | 0.0 | 1.0 | 0.0 |
| KPOFCINO_86 | 0.0 | 1.0 | 0.0 |
| KPOFCINO_87 | 0.0 | 1.0 | 0.0 |
| KPOFCINO_88 | 0.0 | 1.0 | 0.0 |
| KPOFCINO_89 | 0.0 | 1.0 | 0.0 |
| KPOFCINO_90 | 0.0 | 1.0 | 0.0 |
| KPOFCINO_91 | 0.0 | 1.0 | 0.0 |
| KPOFCINO_92 | 1.0 | 0.0 | 1.0 |
| KPOFCINO_93 | 0.0 | 1.0 | 0.0 |
| KPOFCINO_94 | 0.0 | 1.0 | 0.0 |
| KPOFCINO_95 | 0.0 | 1.0 | 0.0 |
| KPOFCINO_96 | 0.0 | 1.0 | 0.0 |
| KPOFCINO_97 | 0.0 | 1.0 | 0.0 |
| KPOFCINO_98 | 0.0 | 1.0 | 0.0 |
| KPOFCINO_99 | 0.0 | 1.0 | 0.0 |
| KPOFCINO_101 | 0.0 | 1.0 | 0.0 |
| KPOFCINO_102 | 0.0 | 1.0 | 0.0 |
| KPOFCINO_104 | 0.0 | 1.0 | 0.0 |
| KPOFCINO_105 | 0.0 | 1.0 | 0.0 |
| KPOFCINO_106 | 0.0 | 1.0 | 0.0 |
| KPOFCINO_107 | 0.0 | 1.0 | 0.0 |
| KPOFCINO_108 | 0.0 | 1.0 | 0.0 |
| KPOFCINO_109 | 0.0 | 1.0 | 0.0 |
| KPOFCINO_110 | 0.0 | 1.0 | 0.0 |
| KPOFCINO_111 | 0.0 | 1.0 | 0.0 |
| KPOFCINO_112 | 0.0 | 1.0 | 0.0 |
| KPOFCINO_113 | 0.0 | 1.0 | 0.0 |
| KPOFCINO_114 | 0.0 | 1.0 | 0.0 |
PlasmidHunter v 1.4.5 (Database: May. 2024 release)
Prophage
Phigaro
| Query ID | Begin | End | Transposable | Taxonomy | pVOGs |
|---|---|---|---|---|---|
| No hit found | |||||
Phigaro v2.4.0 (Database: Jan. 2024 release)