Probiotic potential risk score
| ARGs | VFs | PGs | PPRS |
|---|---|---|---|
| 0 | 25 | 32 | 40.61 |
PPRS is classified as low-risk (≤4), medium-risk (4-6), and high-risk (≥6).
Antibiotic resistance genes
Comprehensive Antibiotic Resistance Database (CARD)
| Query ID | Begin | End | ARO name | ARO accession | CARD name | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
RGI v6.0.3 (Database: CARD Variants v4.0.2, Nov. 2023 release)
ResFinder
| Query ID | Begin | End | Resistance gene | Phenotype | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|
| No hit found | |||||||
ResFinder v4.6.0 (Database: resfinder_db, Aug. 2024 release)
AMRFinderPlus
| Query ID | Begin | End | Gene symbol | Sequence name | Method | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
AMRFinderPlus v4.0.3 (Database: Oct. 2024 release)
Virulence factors
Virulence Factor Database (VFDB)
| Query ID | qstart | qend | Gene name | e-value | VF name | VF category | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|---|
| PFGKIKKO_66 | 9364 | 10203 | cbpD | 0.0 | Autolysin | Exoenzyme | 100.00 | 100.00 | WP_011226733 |
| PFGKIKKO_29 | 15407 | 16000 | STR_RS05880 | 0.0 | Capsule | Immune modulation | 100.00 | 100.00 | WP_011226149 |
| PFGKIKKO_24 | 22534 | 23589 | STU_RS16235 | 0.0 | Capsule | Immune modulation | 100.00 | 100.00 | WP_002948022 |
| PFGKIKKO_24 | 19560 | 20516 | STU_RS16250 | 0.0 | Capsule | Immune modulation | 99.90 | 100.00 | WP_011226328 |
| PFGKIKKO_24 | 20500 | 21309 | STU_RS16245 | 0.0 | Capsule | Immune modulation | 99.88 | 100.00 | WP_002948020 |
| PFGKIKKO_29 | 15407 | 16000 | STER_RS06030 | 0.0 | Capsule | Immune modulation | 99.83 | 100.00 | WP_011226149 |
| PFGKIKKO_29 | 15407 | 16000 | STU_RS15260 | 0.0 | Capsule | Immune modulation | 99.83 | 100.00 | WP_011226149 |
| PFGKIKKO_24 | 23586 | 25370 | STU_RS16230 | 0.0 | Capsule | Immune modulation | 99.83 | 100.00 | WP_011226325 |
| PFGKIKKO_24 | 21309 | 22514 | STU_RS16240 | 0.0 | Capsule | Immune modulation | 99.83 | 100.00 | WP_011226326 |
| PFGKIKKO_24 | 18415 | 19563 | STU_RS16255 | 0.0 | Capsule | Immune modulation | 99.74 | 100.00 | WP_041828290 |
| PFGKIKKO_76 | 293 | 1951 | fbp54 | 0.0 | FBPs | Adherence | 99.46 | 100.00 | WP_011227179 |
| PFGKIKKO_116 | 781 | 1571 | cshA | 0.0 | Cell surface hydrophobicity proteins | Adherence | 99.37 | 100.00 | - |
| PFGKIKKO_29 | 14538 | 15407 | rfbA | 0.0 | Capsule | Immune modulation | 99.31 | 100.00 | WP_011681286 |
| PFGKIKKO_24 | 15756 | 16718 | STU_RS16260 | 0.0 | Capsule | Immune modulation | 98.96 | 95.25 | WP_011226330 |
| PFGKIKKO_61 | 8540 | 9301 | srtA | 0.0 | Sortase A | Exoenzyme | 98.82 | 100.00 | - |
| PFGKIKKO_39 | 14019 | 14750 | STR_RS05260 | 0.0 | Capsule | Immune modulation | 98.63 | 100.00 | WP_011227248 |
| PFGKIKKO_39 | 14019 | 14750 | STER_RS05315 | 0.0 | Capsule | Immune modulation | 98.50 | 100.00 | WP_011681176 |
| PFGKIKKO_39 | 14019 | 14750 | STU_RS14645 | 0.0 | Capsule | Immune modulation | 98.50 | 100.00 | WP_011226048 |
| PFGKIKKO_39 | 11145 | 12510 | STER_RS05300 | 0.0 | Capsule | Immune modulation | 97.95 | 99.85 | WP_011681173 |
| PFGKIKKO_39 | 14751 | 16206 | STER_RS05320 | 0.0 | Capsule | Immune modulation | 97.73 | 99.66 | WP_011681177 |
| PFGKIKKO_24 | 14482 | 15753 | STU_RS16265 | 0.0 | Capsule | Immune modulation | 97.41 | 99.76 | WP_011226331 |
| PFGKIKKO_39 | 13318 | 14010 | STR_RS05255 | 0.0 | Capsule | Immune modulation | 97.26 | 100.00 | WP_011227247 |
| PFGKIKKO_39 | 13318 | 14010 | STU_RS14640 | 0.0 | Capsule | Immune modulation | 97.26 | 100.00 | WP_011226047 |
| PFGKIKKO_24 | 12530 | 13381 | rfbD | 0.0 | Capsule | Immune modulation | 97.18 | 100.00 | WP_014621820 |
| PFGKIKKO_39 | 14751 | 16206 | STU_RS14650 | 0.0 | Capsule | Immune modulation | 97.11 | 99.86 | WP_011226049 |
| PFGKIKKO_39 | 14751 | 16206 | STR_RS05265 | 0.0 | Capsule | Immune modulation | 96.36 | 99.86 | WP_041827043 |
| PFGKIKKO_39 | 12571 | 13308 | STER_RS05305 | 0.0 | Capsule | Immune modulation | 95.94 | 99.60 | WP_011681174 |
| PFGKIKKO_39 | 12571 | 13308 | STU_RS14635 | 0.0 | Capsule | Immune modulation | 95.66 | 99.60 | WP_011226046 |
| PFGKIKKO_39 | 12573 | 13308 | STR_RS05250 | 0.0 | Capsule | Immune modulation | 95.65 | 98.13 | WP_011227246 |
| PFGKIKKO_44 | 11864 | 16759 | SAG_RS09105 | 0.0 | Agglutinin receptor | Adherence | 95.45 | 99.96 | WP_000167699 |
| PFGKIKKO_44 | 11864 | 16807 | SSU98_0978 | 0.0 | Agglutinin receptor | Adherence | 95.25 | 99.78 | YP_001200536 |
| PFGKIKKO_44 | 11864 | 16807 | SSU05_0965 | 0.0 | Agglutinin receptor | Adherence | 95.23 | 99.78 | YP_001198331 |
| PFGKIKKO_39 | 11143 | 12510 | STU_RS14630 | 0.0 | Capsule | Immune modulation | 94.59 | 100.00 | WP_011226045 |
| PFGKIKKO_39 | 13318 | 14010 | STER_RS05310 | 0.0 | Capsule | Immune modulation | 88.20 | 99.71 | WP_011681175 |
| PFGKIKKO_95 | 3385 | 4688 | eno | 0.0 | Streptococcal enolase | Exoenzyme | 88.02 | 99.54 | WP_000022832 |
| PFGKIKKO_81 | 182 | 1192 | plr/gapA | 0.0 | Streptococcal plasmin receptor/GAPDH | Adherence | 86.92 | 99.51 | WP_002986042 |
| PFGKIKKO_29 | 16429 | 17475 | rfbB | 0.0 | Capsule | Immune modulation | 80.71 | 100.00 | WP_009659423 |
| PFGKIKKO_30 | 5704 | 6987 | tig/ropA | 0.0 | Trigger factor | Stress survival | 80.65 | 99.77 | WP_000107753 |
BLASTN v2.16.0 (Database: VFDB, Dec. 2024 release)
VirulenceFinder
| Query ID | Begin | End | Database | Virulence factor | Protein function | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
VirulenceFinder v2.0. 4 (Database: virulencefinder_db, Feb . 2024 release)
Pathogenic genes
PHI-base
| Query ID | qstart | qend | Gene name | e-value | Function | Identity | Coverage | Gene ID |
|---|---|---|---|---|---|---|---|---|
| PFGKIKKO_44 | 16780 | 11867 | B9H01_RS04765 | 0.0 | glucan-binding protein | 96.40 | 99.70 | AUS90958 |
| PFGKIKKO_61 | 5853 | 4870 | ldh(Sp_1220) | 0.0 | L-lactate dehydrogenase | 94.82 | 100.00 | AAK75326 |
| PFGKIKKO_97 | 2125 | 3198 | MntE | 0.0 | manganese homeostasis | 94.41 | 99.72 | ABF32167 |
| PFGKIKKO_41 | 15531 | 13228 | pfl2(Sp_0459) | 0.0 | formate acetyltransferase | 93.23 | 99.22 | AAK74619 |
| PFGKIKKO_96 | 20893 | 19925 | spr0084 | 0.0 | pathogenitcity related | 93.19 | 98.48 | AAK98888 |
| PFGKIKKO_27 | 4227 | 2746 | SPD_0310 | 0.0 | UPF0371 protein SPD_0310 | 92.11 | 100.00 | ABJ54480 |
| PFGKIKKO_49 | 4942 | 7188 | metE | 0.0 | methionine biosynthesis enzymes | 91.86 | 100.00 | AAK74738 |
| PFGKIKKO_14 | 1 | 957 | prsA2 | 0.0 | ribose-phosphate pyrophosphokinase | 90.60 | 98.46 | ABF36968 |
| PFGKIKKO_2 | 28508 | 27357 | potA | 0.0 | ABC transporter ATP-binding protein-spermidine/putrescine transport | 89.32 | 99.74 | AAL00050 |
| PFGKIKKO_50 | 6666 | 4936 | ptsI | 0.0 | phosphoenolpyruvate-protein phosphotransferase | 87.87 | 100.00 | AAK34199 |
| PFGKIKKO_85 | 25983 | 24505 | IMPDH | 0.0 | inosine-5'-monophosphate dehydrogenase | 87.42 | 100.00 | ADE32434 |
| PFGKIKKO_24 | 1 | 1485 | uvrB | 0.0 | excinuclease ABC, B subunit | 87.07 | 74.66 | AE014259_2 |
| PFGKIKKO_95 | 4688 | 3387 | Eno | 0.0 | enolase | 86.21 | 99.77 | ABP90468 |
| PFGKIKKO_85 | 11248 | 9356 | gidA | 0.0 | tRNA uridine 5-carboxymethylaminomethyl modification enzyme | 85.74 | 98.90 | ABP91129 |
| PFGKIKKO_42 | 10009 | 11115 | recA | 0.0 | DNA recombination and repair | 84.91 | 95.36 | AAL00560 |
| PFGKIKKO_49 | 10113 | 8404 | PGM | 0.0 | phosphoglucomutase | 83.71 | 99.65 | ACH87041 |
| PFGKIKKO_36 | 2031 | 1021 | pdh | 0.0 | pyruvate dehydrogenase | 83.09 | 99.70 | ABP91006 |
| PFGKIKKO_89 | 2158 | 797 | mnmE | 0.0 | central tRNA-modifying GTPase | 82.24 | 99.56 | ABP90420 |
| PFGKIKKO_22 | 13314 | 12424 | bglB | 2.56e-180 | putative phospho--glucosidase | 88.89 | 99.66 | AAK33487 |
| PFGKIKKO_64 | 1217 | 282 | SP_0676 | 4.24e-170 | transcription facot | 81.73 | 96.89 | AAK74821 |
| PFGKIKKO_49 | 7380 | 8237 | metF | 7.32e-167 | methionine biosynthesis enzymes | 86.36 | 99.31 | AAK74739 |
| PFGKIKKO_37 | 11888 | 12592 | covR | 3.81e-132 | responder protein | 84.68 | 100.00 | AAK71319 |
| PFGKIKKO_49 | 14067 | 14735 | CiaR | 2.70e-122 | two-component response regulator | 85.65 | 99.55 | AAK74935 |
| PFGKIKKO_37 | 11888 | 12592 | walR | 2.73e-122 | DNA-binding response regulator | 80.85 | 100.00 | ANC99504 |
| PFGKIKKO_49 | 14067 | 14738 | ciaR | 3.04e-120 | two component system response regulator | 83.48 | 99.12 | AIK75708 |
| PFGKIKKO_57 | 7827 | 7141 | CovR | 7.03e-120 | serves to repress GAS virulence factor-encoding genes | 80.79 | 100.00 | ACE75886 |
| PFGKIKKO_42 | 11298 | 11672 | SpxA2 | 1.11e-71 | transcriptional regulator | 91.20 | 94.70 | ERL21461 |
| PFGKIKKO_86 | 6298 | 6699 | SpxA1 | 1.45e-68 | transcriptional regulator | 80.60 | 100.00 | ERL19273 |
| PFGKIKKO_107 | 13664 | 13951 | spr0479 | 2.98e-49 | essential gene | 86.46 | 98.97 | AAK99283 |
| PFGKIKKO_52 | 55643 | 55933 | spr0177 | 1.88e-46 | essential gene | 81.00 | 98.02 | AAK98981 |
| PFGKIKKO_55 | 4249 | 4503 | spr1327 | 2.10e-46 | essential gene | 95.29 | 100.00 | AAL00131 |
| PFGKIKKO_52 | 54840 | 55103 | spr0175 | 3.69e-42 | pathogenitcity related | 84.09 | 100.00 | AAK98979 |
| PFGKIKKO_30 | 7145 | 7645 | RopE (M5005_Spy_1611) | 2.15e-76 | probable DNA-directed RNA polymerase subunit delta | 81.44 | 87.43 | AAK34603 |
| PFGKIKKO_41 | 15531 | 13234 | PFL (B9H01_RS01125) | 0.0 | formate C-acetyltransferase | 83.07 | 98.08 | MYN69560 |
| PFGKIKKO_23 | 33947 | 32928 | ilvC (SPD_0406) | 0.0 | ketol-acid reductoisomerase (NADP(+)) | 96.47 | 100.00 | ABJ55451 |
BLASTX v2.16.0 (Database: PHI base v4.16, May. 2024 release)
Plasmid
PlasmidFinder
| Query ID | Begin | End | Plasmid | Query / Template | Identity | Accession no. |
|---|---|---|---|---|---|---|
| No hit found | ||||||
PlasmidFinder v 2.1.6 (Database: plasmidfinder_db v 2.2.0 , Nov. 2024 release)
PlasmidHunter
| Query ID | Prediction | Chromosome | Plasmid |
|---|---|---|---|
| PFGKIKKO_1 | 0.0 | 1.0 | 0.0 |
| PFGKIKKO_2 | 0.0 | 1.0 | 0.0 |
| PFGKIKKO_3 | 0.0 | 1.0 | 0.0 |
| PFGKIKKO_4 | 0.0 | 1.0 | 0.0 |
| PFGKIKKO_5 | 0.0 | 1.0 | 0.0 |
| PFGKIKKO_6 | 0.0 | 1.0 | 0.0 |
| PFGKIKKO_7 | 0.0 | 1.0 | 0.0 |
| PFGKIKKO_8 | 0.0 | 1.0 | 0.0 |
| PFGKIKKO_9 | 0.0 | 1.0 | 0.0 |
| PFGKIKKO_10 | 0.0 | 1.0 | 0.0 |
| PFGKIKKO_11 | 0.0 | 1.0 | 0.0 |
| PFGKIKKO_12 | 0.0 | 1.0 | 0.0 |
| PFGKIKKO_13 | 0.0 | 1.0 | 0.0 |
| PFGKIKKO_14 | 0.0 | 1.0 | 0.0 |
| PFGKIKKO_22 | 0.0 | 1.0 | 0.0 |
| PFGKIKKO_23 | 0.0 | 1.0 | 0.0 |
| PFGKIKKO_24 | 0.0 | 1.0 | 0.0 |
| PFGKIKKO_25 | 0.0 | 1.0 | 0.0 |
| PFGKIKKO_26 | 0.0 | 1.0 | 0.0 |
| PFGKIKKO_27 | 0.0 | 1.0 | 0.0 |
| PFGKIKKO_28 | 0.0 | 1.0 | 0.0 |
| PFGKIKKO_29 | 0.0 | 1.0 | 0.0 |
| PFGKIKKO_30 | 0.0 | 1.0 | 0.0 |
| PFGKIKKO_31 | 0.0 | 1.0 | 0.0 |
| PFGKIKKO_32 | 0.0 | 1.0 | 0.0 |
| PFGKIKKO_33 | 0.0 | 1.0 | 0.0 |
| PFGKIKKO_34 | 0.0 | 1.0 | 0.0 |
| PFGKIKKO_35 | 0.0 | 1.0 | 0.0 |
| PFGKIKKO_36 | 0.0 | 1.0 | 0.0 |
| PFGKIKKO_37 | 0.0 | 1.0 | 0.0 |
| PFGKIKKO_38 | 0.0 | 1.0 | 0.0 |
| PFGKIKKO_39 | 0.0 | 1.0 | 0.0 |
| PFGKIKKO_40 | 0.0 | 1.0 | 0.0 |
| PFGKIKKO_41 | 0.0 | 1.0 | 0.0 |
| PFGKIKKO_42 | 0.0 | 1.0 | 0.0 |
| PFGKIKKO_43 | 0.0 | 1.0 | 0.0 |
| PFGKIKKO_44 | 0.0 | 1.0 | 0.0 |
| PFGKIKKO_45 | 0.0 | 1.0 | 0.0 |
| PFGKIKKO_46 | 0.0 | 1.0 | 0.0 |
| PFGKIKKO_47 | 0.0 | 1.0 | 0.0 |
| PFGKIKKO_48 | 0.0 | 1.0 | 0.0 |
| PFGKIKKO_49 | 0.0 | 1.0 | 0.0 |
| PFGKIKKO_50 | 0.0 | 1.0 | 0.0 |
| PFGKIKKO_51 | 0.0 | 1.0 | 0.0 |
| PFGKIKKO_52 | 0.0 | 1.0 | 0.0 |
| PFGKIKKO_53 | 0.0 | 1.0 | 0.0 |
| PFGKIKKO_54 | 0.0 | 1.0 | 0.0 |
| PFGKIKKO_55 | 0.0 | 1.0 | 0.0 |
| PFGKIKKO_56 | 0.0 | 1.0 | 0.0 |
| PFGKIKKO_57 | 0.0 | 1.0 | 0.0 |
| PFGKIKKO_58 | 0.0 | 1.0 | 0.0 |
| PFGKIKKO_59 | 0.0 | 1.0 | 0.0 |
| PFGKIKKO_60 | 0.0 | 1.0 | 0.0 |
| PFGKIKKO_61 | 0.0 | 1.0 | 0.0 |
| PFGKIKKO_62 | 0.0 | 1.0 | 0.0 |
| PFGKIKKO_63 | 0.0 | 1.0 | 0.0 |
| PFGKIKKO_64 | 0.0 | 1.0 | 0.0 |
| PFGKIKKO_65 | 0.0 | 1.0 | 0.0 |
| PFGKIKKO_66 | 0.0 | 1.0 | 0.0 |
| PFGKIKKO_67 | 0.0 | 1.0 | 0.0 |
| PFGKIKKO_68 | 0.0 | 1.0 | 0.0 |
| PFGKIKKO_69 | 1.0 | 0.0 | 1.0 |
| PFGKIKKO_70 | 0.0 | 1.0 | 0.0 |
| PFGKIKKO_71 | 0.0 | 1.0 | 0.0 |
| PFGKIKKO_72 | 0.0 | 1.0 | 0.0 |
| PFGKIKKO_73 | 0.0 | 1.0 | 0.0 |
| PFGKIKKO_74 | 0.0 | 1.0 | 0.0 |
| PFGKIKKO_75 | 0.0 | 1.0 | 0.0 |
| PFGKIKKO_76 | 0.0 | 1.0 | 0.0 |
| PFGKIKKO_77 | 1.0 | 0.0 | 1.0 |
| PFGKIKKO_78 | 0.0 | 1.0 | 0.0 |
| PFGKIKKO_79 | 0.0 | 1.0 | 0.0 |
| PFGKIKKO_80 | 0.0 | 1.0 | 0.0 |
| PFGKIKKO_81 | 0.0 | 1.0 | 0.0 |
| PFGKIKKO_82 | 0.0 | 1.0 | 0.0 |
| PFGKIKKO_83 | 0.0 | 1.0 | 0.0 |
| PFGKIKKO_84 | 0.0 | 1.0 | 0.0 |
| PFGKIKKO_85 | 0.0 | 1.0 | 0.0 |
| PFGKIKKO_86 | 0.0 | 1.0 | 0.0 |
| PFGKIKKO_87 | 0.0 | 1.0 | 0.0 |
| PFGKIKKO_88 | 0.0 | 1.0 | 0.0 |
| PFGKIKKO_89 | 0.0 | 1.0 | 0.0 |
| PFGKIKKO_90 | 0.0 | 1.0 | 0.0 |
| PFGKIKKO_91 | 0.0 | 1.0 | 0.0 |
| PFGKIKKO_92 | 0.0 | 1.0 | 0.0 |
| PFGKIKKO_93 | 0.0 | 1.0 | 0.0 |
| PFGKIKKO_94 | 0.0 | 1.0 | 0.0 |
| PFGKIKKO_95 | 0.0 | 1.0 | 0.0 |
| PFGKIKKO_96 | 0.0 | 1.0 | 0.0 |
| PFGKIKKO_97 | 0.0 | 1.0 | 0.0 |
| PFGKIKKO_98 | 0.0 | 1.0 | 0.0 |
| PFGKIKKO_99 | 0.0 | 1.0 | 0.0 |
| PFGKIKKO_100 | 0.0 | 1.0 | 0.0 |
| PFGKIKKO_101 | 0.0 | 1.0 | 0.0 |
| PFGKIKKO_102 | 1.0 | 0.0 | 1.0 |
| PFGKIKKO_103 | 0.0 | 1.0 | 0.0 |
| PFGKIKKO_104 | 0.0 | 1.0 | 0.0 |
| PFGKIKKO_105 | 0.0 | 1.0 | 0.0 |
| PFGKIKKO_106 | 0.0 | 1.0 | 0.0 |
| PFGKIKKO_107 | 0.0 | 1.0 | 0.0 |
| PFGKIKKO_108 | 0.0 | 1.0 | 0.0 |
| PFGKIKKO_109 | 0.0 | 1.0 | 0.0 |
| PFGKIKKO_110 | 1.0 | 0.0 | 1.0 |
| PFGKIKKO_111 | 0.0 | 1.0 | 0.0 |
| PFGKIKKO_112 | 0.0 | 1.0 | 0.0 |
| PFGKIKKO_113 | 0.0 | 1.0 | 0.0 |
| PFGKIKKO_114 | 1.0 | 0.0 | 1.0 |
| PFGKIKKO_115 | 0.0 | 1.0 | 0.0 |
| PFGKIKKO_116 | 0.0 | 1.0 | 0.0 |
| PFGKIKKO_117 | 1.0 | 0.0 | 1.0 |
PlasmidHunter v 1.4.5 (Database: May. 2024 release)
Prophage
Phigaro
| Query ID | Begin | End | Transposable | Taxonomy | pVOGs |
|---|---|---|---|---|---|
| No hit found | |||||
Phigaro v2.4.0 (Database: Jan. 2024 release)