Probiotic potential risk score
| ARGs | VFs | PGs | PPRS |
|---|---|---|---|
| 0 | 22 | 33 | 39.66 |
PPRS is classified as low-risk (≤4), medium-risk (4-6), and high-risk (≥6).
Antibiotic resistance genes
Comprehensive Antibiotic Resistance Database (CARD)
| Query ID | Begin | End | ARO name | ARO accession | CARD name | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
RGI v6.0.3 (Database: CARD Variants v4.0.2, Nov. 2023 release)
ResFinder
| Query ID | Begin | End | Resistance gene | Phenotype | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|
| No hit found | |||||||
ResFinder v4.6.0 (Database: resfinder_db, Aug. 2024 release)
AMRFinderPlus
| Query ID | Begin | End | Gene symbol | Sequence name | Method | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
AMRFinderPlus v4.0.3 (Database: Oct. 2024 release)
Virulence factors
Virulence Factor Database (VFDB)
| Query ID | qstart | qend | Gene name | e-value | VF name | VF category | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|---|
| FDAJCDNG_7 | 16236 | 17045 | STU_RS16245 | 0.0 | Capsule | Immune modulation | 100.00 | 100.00 | WP_002948020 |
| FDAJCDNG_2 | 25406 | 25999 | STR_RS05880 | 0.0 | Capsule | Immune modulation | 99.83 | 100.00 | WP_011226149 |
| FDAJCDNG_7 | 17982 | 19130 | STU_RS16255 | 0.0 | Capsule | Immune modulation | 99.74 | 100.00 | WP_041828290 |
| FDAJCDNG_7 | 13956 | 15011 | STU_RS16235 | 0.0 | Capsule | Immune modulation | 99.72 | 100.00 | WP_002948022 |
| FDAJCDNG_2 | 25406 | 25999 | STER_RS06030 | 0.0 | Capsule | Immune modulation | 99.66 | 100.00 | WP_011226149 |
| FDAJCDNG_2 | 25406 | 25999 | STU_RS15260 | 0.0 | Capsule | Immune modulation | 99.66 | 100.00 | WP_011226149 |
| FDAJCDNG_17 | 26831 | 27670 | cbpD | 0.0 | Autolysin | Exoenzyme | 99.64 | 100.00 | WP_011226733 |
| FDAJCDNG_7 | 17029 | 17985 | STU_RS16250 | 0.0 | Capsule | Immune modulation | 99.58 | 100.00 | WP_011226328 |
| FDAJCDNG_2 | 24537 | 25406 | rfbA | 0.0 | Capsule | Immune modulation | 99.42 | 100.00 | WP_011681286 |
| FDAJCDNG_7 | 15031 | 16236 | STU_RS16240 | 0.0 | Capsule | Immune modulation | 99.42 | 100.00 | WP_011226326 |
| FDAJCDNG_25 | 113 | 1771 | fbp54 | 0.0 | FBPs | Adherence | 99.40 | 100.00 | WP_011227179 |
| FDAJCDNG_7 | 12177 | 13959 | STU_RS16230 | 0.0 | Capsule | Immune modulation | 99.38 | 99.89 | WP_011226325 |
| FDAJCDNG_34 | 16583 | 17373 | cshA | 0.0 | Cell surface hydrophobicity proteins | Adherence | 98.74 | 100.00 | - |
| FDAJCDNG_18 | 17153 | 17914 | srtA | 0.0 | Sortase A | Exoenzyme | 98.69 | 100.00 | - |
| FDAJCDNG_21 | 11773 | 13227 | STU_RS14650 | 0.0 | Capsule | Immune modulation | 98.28 | 100.00 | WP_011226049 |
| FDAJCDNG_21 | 13228 | 13959 | STR_RS05260 | 0.0 | Capsule | Immune modulation | 98.22 | 100.00 | WP_011227248 |
| FDAJCDNG_61 | 2448 | 3863 | STER_RS05250 | 0.0 | Capsule | Immune modulation | 98.02 | 100.00 | WP_011681165 |
| FDAJCDNG_21 | 11773 | 13227 | STR_RS05265 | 0.0 | Capsule | Immune modulation | 97.87 | 100.00 | WP_041827043 |
| FDAJCDNG_21 | 13228 | 13959 | STU_RS14645 | 0.0 | Capsule | Immune modulation | 97.81 | 100.00 | WP_011226048 |
| FDAJCDNG_21 | 11773 | 13227 | STER_RS05320 | 0.0 | Capsule | Immune modulation | 97.40 | 99.79 | WP_011681177 |
| FDAJCDNG_21 | 14670 | 15410 | STER_RS05305 | 0.0 | Capsule | Immune modulation | 97.30 | 100.00 | WP_011681174 |
| FDAJCDNG_7 | 19233 | 20084 | rfbD | 0.0 | Capsule | Immune modulation | 96.83 | 100.00 | WP_014621820 |
| FDAJCDNG_21 | 14670 | 15405 | STR_RS05250 | 0.0 | Capsule | Immune modulation | 96.74 | 98.13 | WP_011227246 |
| FDAJCDNG_21 | 13228 | 13959 | STER_RS05315 | 0.0 | Capsule | Immune modulation | 96.72 | 100.00 | WP_011681176 |
| FDAJCDNG_21 | 14670 | 15410 | STU_RS14635 | 0.0 | Capsule | Immune modulation | 96.63 | 100.00 | WP_011226046 |
| FDAJCDNG_21 | 13968 | 14660 | STR_RS05255 | 0.0 | Capsule | Immune modulation | 95.81 | 100.00 | WP_011227247 |
| FDAJCDNG_21 | 13968 | 14660 | STU_RS14640 | 0.0 | Capsule | Immune modulation | 95.81 | 100.00 | WP_011226047 |
| FDAJCDNG_21 | 13968 | 14660 | STER_RS05310 | 0.0 | Capsule | Immune modulation | 89.75 | 100.00 | WP_011681175 |
| FDAJCDNG_12 | 16111 | 17414 | eno | 0.0 | Streptococcal enolase | Exoenzyme | 88.02 | 99.54 | WP_000022832 |
| FDAJCDNG_32 | 14288 | 15298 | plr/gapA | 0.0 | Streptococcal plasmin receptor/GAPDH | Adherence | 87.17 | 99.80 | WP_002986042 |
| FDAJCDNG_29 | 2112 | 3395 | tig/ropA | 0.0 | Trigger factor | Stress survival | 80.65 | 99.77 | WP_000107753 |
| FDAJCDNG_2 | 26428 | 27474 | rfbB | 0.0 | Capsule | Immune modulation | 80.61 | 100.00 | WP_009659423 |
BLASTN v2.16.0 (Database: VFDB, Dec. 2024 release)
VirulenceFinder
| Query ID | Begin | End | Database | Virulence factor | Protein function | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
VirulenceFinder v2.0. 4 (Database: virulencefinder_db, Feb . 2024 release)
Pathogenic genes
PHI-base
| Query ID | qstart | qend | Gene name | e-value | Function | Identity | Coverage | Gene ID |
|---|---|---|---|---|---|---|---|---|
| FDAJCDNG_18 | 14466 | 13483 | ldh(Sp_1220) | 0.0 | L-lactate dehydrogenase | 94.82 | 100.00 | AAK75326 |
| FDAJCDNG_11 | 26166 | 27239 | MntE | 0.0 | manganese homeostasis | 94.41 | 99.72 | ABF32167 |
| FDAJCDNG_23 | 17070 | 14767 | pfl2(Sp_0459) | 0.0 | formate acetyltransferase | 93.23 | 99.22 | AAK74619 |
| FDAJCDNG_1 | 33905 | 32937 | spr0084 | 0.0 | pathogenitcity related | 92.57 | 98.48 | AAK98888 |
| FDAJCDNG_28 | 11358 | 9112 | metE | 0.0 | methionine biosynthesis enzymes | 91.86 | 100.00 | AAK74738 |
| FDAJCDNG_13 | 13659 | 12178 | SPD_0310 | 0.0 | UPF0371 protein SPD_0310 | 91.70 | 100.00 | ABJ54480 |
| FDAJCDNG_17 | 8042 | 7050 | recA | 0.0 | DNA recombination and repair | 91.24 | 85.31 | AAL00560 |
| FDAJCDNG_27 | 15292 | 14321 | prsA2 | 0.0 | ribose-phosphate pyrophosphokinase | 90.12 | 100.00 | ABF36968 |
| FDAJCDNG_8 | 24147 | 22996 | potA | 0.0 | ABC transporter ATP-binding protein-spermidine/putrescine transport | 89.06 | 99.74 | AAL00050 |
| FDAJCDNG_7 | 35004 | 33016 | uvrB | 0.0 | excinuclease ABC, B subunit | 88.99 | 100.00 | AE014259_2 |
| FDAJCDNG_2 | 3389 | 5119 | ptsI | 0.0 | phosphoenolpyruvate-protein phosphotransferase | 87.69 | 100.00 | AAK34199 |
| FDAJCDNG_16 | 1540 | 62 | IMPDH | 0.0 | inosine-5'-monophosphate dehydrogenase | 87.42 | 100.00 | ADE32434 |
| FDAJCDNG_12 | 16111 | 17412 | Eno | 0.0 | enolase | 86.21 | 99.77 | ABP90468 |
| FDAJCDNG_67 | 45752 | 43860 | gidA | 0.0 | tRNA uridine 5-carboxymethylaminomethyl modification enzyme | 86.05 | 98.90 | ABP91129 |
| FDAJCDNG_28 | 6186 | 7895 | PGM | 0.0 | phosphoglucomutase | 83.71 | 99.65 | ACH87041 |
| FDAJCDNG_45 | 55011 | 54001 | pdh | 0.0 | pyruvate dehydrogenase | 83.09 | 99.70 | ABP91006 |
| FDAJCDNG_3 | 14076 | 12715 | mnmE | 0.0 | central tRNA-modifying GTPase | 82.02 | 99.56 | ABP90420 |
| FDAJCDNG_45 | 4699 | 6591 | PepO | 0.0 | endopeptidase | 80.03 | 100.00 | ABF32980 |
| FDAJCDNG_12 | 1667 | 2557 | bglB | 6.48e-180 | putative phospho--glucosidase | 88.89 | 99.66 | AAK33487 |
| FDAJCDNG_5 | 1262 | 324 | SP_0676 | 2.76e-169 | transcription facot | 81.15 | 97.20 | AAK74821 |
| FDAJCDNG_28 | 8920 | 8063 | metF | 7.86e-167 | methionine biosynthesis enzymes | 86.36 | 99.31 | AAK74739 |
| FDAJCDNG_34 | 45068 | 45772 | covR | 5.90e-131 | responder protein | 84.68 | 100.00 | AAK71319 |
| FDAJCDNG_15 | 16473 | 15802 | rr01 | 9.14e-126 | response regulator | 83.93 | 99.56 | CAB54566 |
| FDAJCDNG_28 | 2232 | 1564 | CiaR | 1.61e-122 | two-component response regulator | 85.65 | 99.55 | AAK74935 |
| FDAJCDNG_34 | 45068 | 45772 | walR | 2.56e-122 | DNA-binding response regulator | 81.28 | 100.00 | ANC99504 |
| FDAJCDNG_28 | 2232 | 1561 | ciaR | 1.92e-120 | two component system response regulator | 83.48 | 99.12 | AIK75708 |
| FDAJCDNG_22 | 16041 | 16727 | CovR | 1.22e-119 | serves to repress GAS virulence factor-encoding genes | 80.79 | 100.00 | ACE75886 |
| FDAJCDNG_17 | 6753 | 6358 | SpxA2 | 5.53e-76 | transcriptional regulator | 90.91 | 100.00 | ERL21461 |
| FDAJCDNG_3 | 25352 | 25753 | SpxA1 | 8.90e-68 | transcriptional regulator | 80.60 | 100.00 | ERL19273 |
| FDAJCDNG_6 | 27648 | 27361 | spr0479 | 3.11e-49 | essential gene | 86.46 | 98.97 | AAK99283 |
| FDAJCDNG_1 | 64862 | 64608 | spr1327 | 1.89e-45 | essential gene | 95.29 | 100.00 | AAL00131 |
| FDAJCDNG_67 | 12126 | 12389 | spr0175 | 2.84e-42 | pathogenitcity related | 84.09 | 100.00 | AAK98979 |
| FDAJCDNG_67 | 12929 | 13219 | spr0177 | 3.62e-37 | essential gene | 80.00 | 98.02 | AAK98981 |
| FDAJCDNG_29 | 3553 | 4053 | RopE (M5005_Spy_1611) | 4.42e-77 | probable DNA-directed RNA polymerase subunit delta | 81.44 | 87.43 | AAK34603 |
| FDAJCDNG_23 | 17070 | 14773 | PFL (B9H01_RS01125) | 0.0 | formate C-acetyltransferase | 83.07 | 98.08 | MYN69560 |
| FDAJCDNG_45 | 19161 | 20180 | ilvC (SPD_0406) | 0.0 | ketol-acid reductoisomerase (NADP(+)) | 96.47 | 100.00 | ABJ55451 |
BLASTX v2.16.0 (Database: PHI base v4.16, May. 2024 release)
Plasmid
PlasmidFinder
| Query ID | Begin | End | Plasmid | Query / Template | Identity | Accession no. |
|---|---|---|---|---|---|---|
| No hit found | ||||||
PlasmidFinder v 2.1.6 (Database: plasmidfinder_db v 2.2.0 , Nov. 2024 release)
PlasmidHunter
| Query ID | Prediction | Chromosome | Plasmid |
|---|---|---|---|
| FDAJCDNG_1 | 0.0 | 1.0 | 0.0 |
| FDAJCDNG_2 | 0.0 | 1.0 | 0.0 |
| FDAJCDNG_3 | 0.0 | 1.0 | 0.0 |
| FDAJCDNG_4 | 0.0 | 1.0 | 0.0 |
| FDAJCDNG_5 | 0.0 | 1.0 | 0.0 |
| FDAJCDNG_6 | 0.0 | 1.0 | 0.0 |
| FDAJCDNG_7 | 0.0 | 1.0 | 0.0 |
| FDAJCDNG_8 | 0.0 | 1.0 | 0.0 |
| FDAJCDNG_9 | 0.0 | 1.0 | 0.0 |
| FDAJCDNG_10 | 0.0 | 1.0 | 0.0 |
| FDAJCDNG_11 | 0.0 | 1.0 | 0.0 |
| FDAJCDNG_12 | 0.0 | 1.0 | 0.0 |
| FDAJCDNG_13 | 0.0 | 1.0 | 0.0 |
| FDAJCDNG_14 | 0.0 | 1.0 | 0.0 |
| FDAJCDNG_15 | 0.0 | 1.0 | 0.0 |
| FDAJCDNG_16 | 0.0 | 1.0 | 0.0 |
| FDAJCDNG_17 | 0.0 | 1.0 | 0.0 |
| FDAJCDNG_18 | 0.0 | 1.0 | 0.0 |
| FDAJCDNG_19 | 0.0 | 1.0 | 0.0 |
| FDAJCDNG_20 | 0.0 | 1.0 | 0.0 |
| FDAJCDNG_21 | 0.0 | 1.0 | 0.0 |
| FDAJCDNG_22 | 0.0 | 1.0 | 0.0 |
| FDAJCDNG_23 | 0.0 | 1.0 | 0.0 |
| FDAJCDNG_24 | 0.0 | 1.0 | 0.0 |
| FDAJCDNG_25 | 0.0 | 1.0 | 0.0 |
| FDAJCDNG_26 | 0.0 | 1.0 | 0.0 |
| FDAJCDNG_27 | 0.0 | 1.0 | 0.0 |
| FDAJCDNG_28 | 0.0 | 1.0 | 0.0 |
| FDAJCDNG_29 | 0.0 | 1.0 | 0.0 |
| FDAJCDNG_30 | 0.0 | 1.0 | 0.0 |
| FDAJCDNG_31 | 0.0 | 1.0 | 0.0 |
| FDAJCDNG_32 | 0.0 | 1.0 | 0.0 |
| FDAJCDNG_33 | 0.0 | 1.0 | 0.0 |
| FDAJCDNG_34 | 0.0 | 1.0 | 0.0 |
| FDAJCDNG_35 | 0.0 | 1.0 | 0.0 |
| FDAJCDNG_36 | 0.0 | 1.0 | 0.0 |
| FDAJCDNG_37 | 0.0 | 1.0 | 0.0 |
| FDAJCDNG_38 | 0.0 | 1.0 | 0.0 |
| FDAJCDNG_39 | 0.0 | 1.0 | 0.0 |
| FDAJCDNG_40 | 0.0 | 1.0 | 0.0 |
| FDAJCDNG_41 | 1.0 | 0.0 | 1.0 |
| FDAJCDNG_42 | 1.0 | 0.0 | 1.0 |
| FDAJCDNG_43 | 0.0 | 1.0 | 0.0 |
| FDAJCDNG_44 | 0.0 | 1.0 | 0.0 |
| FDAJCDNG_45 | 0.0 | 1.0 | 0.0 |
| FDAJCDNG_46 | 0.0 | 1.0 | 0.0 |
| FDAJCDNG_47 | 1.0 | 0.0 | 1.0 |
| FDAJCDNG_48 | 0.0 | 1.0 | 0.0 |
| FDAJCDNG_49 | 0.0 | 1.0 | 0.0 |
| FDAJCDNG_50 | 0.0 | 1.0 | 0.0 |
| FDAJCDNG_51 | 0.0 | 1.0 | 0.0 |
| FDAJCDNG_52 | 0.0 | 1.0 | 0.0 |
| FDAJCDNG_53 | 1.0 | 0.0 | 1.0 |
| FDAJCDNG_54 | 0.0 | 1.0 | 0.0 |
| FDAJCDNG_55 | 1.0 | 0.0 | 1.0 |
| FDAJCDNG_56 | 0.0 | 1.0 | 0.0 |
| FDAJCDNG_57 | 1.0 | 0.0 | 1.0 |
| FDAJCDNG_58 | 0.0 | 1.0 | 0.0 |
| FDAJCDNG_59 | 0.0 | 1.0 | 0.0 |
| FDAJCDNG_60 | 0.0 | 1.0 | 0.0 |
| FDAJCDNG_61 | 1.0 | 0.0 | 1.0 |
| FDAJCDNG_62 | 0.0 | 1.0 | 0.0 |
| FDAJCDNG_63 | 0.0 | 1.0 | 0.0 |
| FDAJCDNG_64 | 0.0 | 1.0 | 0.0 |
| FDAJCDNG_65 | 0.0 | 1.0 | 0.0 |
| FDAJCDNG_66 | 0.0 | 1.0 | 0.0 |
| FDAJCDNG_67 | 0.0 | 1.0 | 0.0 |
| FDAJCDNG_68 | 0.0 | 1.0 | 0.0 |
| FDAJCDNG_69 | 0.0 | 1.0 | 0.0 |
| FDAJCDNG_70 | 1.0 | 0.0 | 1.0 |
| FDAJCDNG_71 | 1.0 | 0.0 | 1.0 |
| FDAJCDNG_72 | 1.0 | 0.0 | 1.0 |
| FDAJCDNG_73 | 0.0 | 1.0 | 0.0 |
| FDAJCDNG_74 | 1.0 | 0.0 | 1.0 |
| FDAJCDNG_75 | 0.0 | 1.0 | 0.0 |
| FDAJCDNG_76 | 0.0 | 1.0 | 0.0 |
| FDAJCDNG_77 | 0.0 | 1.0 | 0.0 |
| FDAJCDNG_78 | 0.0 | 1.0 | 0.0 |
| FDAJCDNG_79 | 0.0 | 1.0 | 0.0 |
| FDAJCDNG_80 | 0.0 | 1.0 | 0.0 |
| FDAJCDNG_81 | 0.0 | 1.0 | 0.0 |
| FDAJCDNG_82 | 0.0 | 1.0 | 0.0 |
| FDAJCDNG_83 | 0.0 | 1.0 | 0.0 |
| FDAJCDNG_84 | 1.0 | 0.0 | 1.0 |
| FDAJCDNG_85 | 0.0 | 1.0 | 0.0 |
| FDAJCDNG_89 | 0.0 | 1.0 | 0.0 |
PlasmidHunter v 1.4.5 (Database: May. 2024 release)
Prophage
Phigaro
| Query ID | Begin | End | Transposable | Taxonomy | pVOGs |
|---|---|---|---|---|---|
| No hit found | |||||
Phigaro v2.4.0 (Database: Jan. 2024 release)