Probiotic potential risk score
| ARGs | VFs | PGs | PPRS |
|---|---|---|---|
| 0 | 32 | 31 | 44.55 |
PPRS is classified as low-risk (≤4), medium-risk (4-6), and high-risk (≥6).
Antibiotic resistance genes
Comprehensive Antibiotic Resistance Database (CARD)
| Query ID | Begin | End | ARO name | ARO accession | CARD name | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
RGI v6.0.3 (Database: CARD Variants v4.0.2, Nov. 2023 release)
ResFinder
| Query ID | Begin | End | Resistance gene | Phenotype | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|
| No hit found | |||||||
ResFinder v4.6.0 (Database: resfinder_db, Aug. 2024 release)
AMRFinderPlus
| Query ID | Begin | End | Gene symbol | Sequence name | Method | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
AMRFinderPlus v4.0.3 (Database: Oct. 2024 release)
Virulence factors
Virulence Factor Database (VFDB)
| Query ID | qstart | qend | Gene name | e-value | VF name | VF category | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|---|
| ODFFANLH_13 | 128 | 967 | cbpD | 0.0 | Autolysin | Exoenzyme | 100.00 | 100.00 | WP_011226733 |
| ODFFANLH_9 | 6056 | 6679 | STU_RS14555 | 0.0 | Capsule | Immune modulation | 100.00 | 100.00 | WP_011226030 |
| ODFFANLH_9 | 8002 | 9402 | STU_RS14565 | 0.0 | Capsule | Immune modulation | 99.93 | 100.00 | WP_179970486 |
| ODFFANLH_41 | 49551 | 50810 | STER_RS07100 | 0.0 | Capsule | Immune modulation | 99.92 | 100.00 | WP_011681445 |
| ODFFANLH_9 | 4827 | 5945 | STU_RS14550 | 0.0 | Capsule | Immune modulation | 99.82 | 100.00 | WP_011226029 |
| ODFFANLH_9 | 6820 | 7995 | STU_RS14560 | 0.0 | Capsule | Immune modulation | 99.75 | 100.00 | WP_011226032 |
| ODFFANLH_23 | 96924 | 97517 | STR_RS05880 | 0.0 | Capsule | Immune modulation | 99.66 | 100.00 | WP_011226149 |
| ODFFANLH_41 | 51801 | 52769 | STER_RS07090 | 0.0 | Capsule | Immune modulation | 99.59 | 100.00 | WP_011681443 |
| ODFFANLH_34 | 92333 | 93991 | fbp54 | 0.0 | FBPs | Adherence | 99.58 | 100.00 | WP_011227179 |
| ODFFANLH_23 | 96924 | 97517 | STER_RS06030 | 0.0 | Capsule | Immune modulation | 99.50 | 100.00 | WP_011226149 |
| ODFFANLH_23 | 96924 | 97517 | STU_RS15260 | 0.0 | Capsule | Immune modulation | 99.50 | 100.00 | WP_011226149 |
| ODFFANLH_9 | 4086 | 4840 | STU_RS14545 | 0.0 | Capsule | Immune modulation | 99.47 | 99.87 | WP_011226028 |
| ODFFANLH_9 | 10918 | 11641 | STU_RS14575 | 0.0 | Capsule | Immune modulation | 99.31 | 99.72 | WP_041828375 |
| ODFFANLH_23 | 97517 | 98386 | rfbA | 0.0 | Capsule | Immune modulation | 99.19 | 100.00 | WP_011681286 |
| ODFFANLH_41 | 50807 | 51783 | STER_RS07095 | 0.0 | Capsule | Immune modulation | 99.18 | 99.90 | WP_011681444 |
| ODFFANLH_9 | 15580 | 16029 | STU_RS14620 | 0.0 | Capsule | Immune modulation | 99.11 | 100.00 | WP_011226042 |
| ODFFANLH_9 | 20136 | 20867 | STR_RS05260 | 0.0 | Capsule | Immune modulation | 99.04 | 100.00 | WP_011227248 |
| ODFFANLH_41 | 52771 | 53486 | STER_RS07085 | 0.0 | Capsule | Immune modulation | 99.02 | 99.86 | WP_011681442 |
| ODFFANLH_9 | 20136 | 20867 | STER_RS05315 | 0.0 | Capsule | Immune modulation | 98.91 | 100.00 | WP_011681176 |
| ODFFANLH_23 | 52106 | 52893 | cshA | 0.0 | Cell surface hydrophobicity proteins | Adherence | 98.86 | 99.62 | - |
| ODFFANLH_9 | 16038 | 17035 | STU_RS14625* | 0.0 | Capsule | Immune modulation | 98.80 | 100.00 | - |
| ODFFANLH_9 | 18685 | 19425 | STER_RS05305 | 0.0 | Capsule | Immune modulation | 98.78 | 100.00 | WP_011681174 |
| ODFFANLH_23 | 132285 | 133046 | srtA | 0.0 | Sortase A | Exoenzyme | 98.56 | 100.00 | - |
| ODFFANLH_9 | 18690 | 19425 | STR_RS05250 | 0.0 | Capsule | Immune modulation | 98.10 | 98.13 | WP_011227246 |
| ODFFANLH_9 | 20868 | 22328 | STER_RS05320 | 0.0 | Capsule | Immune modulation | 97.81 | 100.00 | WP_011681177 |
| ODFFANLH_9 | 20136 | 20867 | STU_RS14645 | 0.0 | Capsule | Immune modulation | 97.81 | 100.00 | WP_011226048 |
| ODFFANLH_9 | 18685 | 19425 | STU_RS14635 | 0.0 | Capsule | Immune modulation | 97.71 | 100.00 | WP_011226046 |
| ODFFANLH_9 | 9899 | 10891 | STU_RS14570 | 0.0 | Capsule | Immune modulation | 97.38 | 100.00 | WP_011226034 |
| ODFFANLH_9 | 20868 | 22328 | STU_RS14650 | 0.0 | Capsule | Immune modulation | 97.19 | 100.21 | WP_011226049 |
| ODFFANLH_41 | 48581 | 49432 | rfbD | 0.0 | Capsule | Immune modulation | 97.07 | 100.00 | WP_014621820 |
| ODFFANLH_41 | 53832 | 54602 | STER_RS07075 | 0.0 | Capsule | Immune modulation | 97.02 | 99.10 | WP_011681440 |
| ODFFANLH_9 | 20868 | 22328 | STR_RS05265 | 0.0 | Capsule | Immune modulation | 96.78 | 100.21 | WP_041827043 |
| ODFFANLH_9 | 17268 | 18631 | STER_RS05300 | 0.0 | Capsule | Immune modulation | 94.87 | 99.71 | WP_011681173 |
| ODFFANLH_9 | 17264 | 18631 | STU_RS14630 | 0.0 | Capsule | Immune modulation | 94.01 | 100.00 | WP_011226045 |
| ODFFANLH_9 | 15095 | 15580 | STU_RS14615 | 0.0 | Capsule | Immune modulation | 90.76 | 99.79 | WP_011226041 |
| ODFFANLH_9 | 19435 | 20127 | STR_RS05255 | 0.0 | Capsule | Immune modulation | 90.48 | 100.00 | WP_011227247 |
| ODFFANLH_9 | 19435 | 20127 | STU_RS14640 | 0.0 | Capsule | Immune modulation | 90.48 | 100.00 | WP_011226047 |
| ODFFANLH_9 | 19435 | 20127 | STER_RS05310 | 0.0 | Capsule | Immune modulation | 89.32 | 100.00 | WP_011681175 |
| ODFFANLH_1 | 119250 | 120553 | eno | 0.0 | Streptococcal enolase | Exoenzyme | 88.09 | 99.54 | WP_000022832 |
| ODFFANLH_21 | 183 | 1193 | plr/gapA | 0.0 | Streptococcal plasmin receptor/GAPDH | Adherence | 86.73 | 99.51 | WP_002986042 |
| ODFFANLH_23 | 95449 | 96495 | rfbB | 0.0 | Capsule | Immune modulation | 80.71 | 100.00 | WP_009659423 |
| ODFFANLH_3 | 62887 | 64170 | tig/ropA | 0.0 | Trigger factor | Stress survival | 80.50 | 99.77 | WP_000107753 |
| ODFFANLH_9 | 11709 | 12047 | STU_RS19955 | 1.16e-175 | Capsule | Immune modulation | 99.70 | 100.00 | WP_148148905 |
BLASTN v2.16.0 (Database: VFDB, Dec. 2024 release)
VirulenceFinder
| Query ID | Begin | End | Database | Virulence factor | Protein function | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
VirulenceFinder v2.0. 4 (Database: virulencefinder_db, Feb . 2024 release)
Pathogenic genes
PHI-base
| Query ID | qstart | qend | Gene name | e-value | Function | Identity | Coverage | Gene ID |
|---|---|---|---|---|---|---|---|---|
| ODFFANLH_23 | 135733 | 136716 | ldh(Sp_1220) | 0.0 | L-lactate dehydrogenase | 94.82 | 100.00 | AAK75326 |
| ODFFANLH_1 | 13754 | 12681 | MntE | 0.0 | manganese homeostasis | 94.41 | 99.72 | ABF32167 |
| ODFFANLH_1 | 202762 | 201794 | spr0084 | 0.0 | pathogenitcity related | 93.19 | 98.48 | AAK98888 |
| ODFFANLH_12 | 55572 | 57875 | pfl2(Sp_0459) | 0.0 | formate acetyltransferase | 92.97 | 99.22 | AAK74619 |
| ODFFANLH_10 | 5568 | 7814 | metE | 0.0 | methionine biosynthesis enzymes | 91.99 | 100.00 | AAK74738 |
| ODFFANLH_38 | 62944 | 61463 | SPD_0310 | 0.0 | UPF0371 protein SPD_0310 | 91.90 | 100.00 | ABJ54480 |
| ODFFANLH_13 | 20626 | 21624 | recA | 0.0 | DNA recombination and repair | 90.99 | 85.82 | AAL00560 |
| ODFFANLH_14 | 1 | 957 | prsA2 | 0.0 | ribose-phosphate pyrophosphokinase | 90.60 | 98.46 | ABF36968 |
| ODFFANLH_2 | 66506 | 67657 | potA | 0.0 | ABC transporter ATP-binding protein-spermidine/putrescine transport | 89.32 | 99.74 | AAL00050 |
| ODFFANLH_41 | 35515 | 37503 | uvrB | 0.0 | excinuclease ABC, B subunit | 88.99 | 100.00 | AE014259_2 |
| ODFFANLH_40 | 27185 | 28663 | IMPDH | 0.0 | inosine-5'-monophosphate dehydrogenase | 87.63 | 100.00 | ADE32434 |
| ODFFANLH_23 | 119537 | 117807 | ptsI | 0.0 | phosphoenolpyruvate-protein phosphotransferase | 87.52 | 100.00 | AAK34199 |
| ODFFANLH_1 | 120553 | 119252 | Eno | 0.0 | enolase | 86.21 | 99.77 | ABP90468 |
| ODFFANLH_40 | 41919 | 43811 | gidA | 0.0 | tRNA uridine 5-carboxymethylaminomethyl modification enzyme | 85.74 | 98.90 | ABP91129 |
| ODFFANLH_10 | 10739 | 9030 | PGM | 0.0 | phosphoglucomutase | 83.89 | 99.65 | ACH87041 |
| ODFFANLH_42 | 19065 | 20075 | pdh | 0.0 | pyruvate dehydrogenase | 83.38 | 99.70 | ABP91006 |
| ODFFANLH_34 | 68105 | 69466 | mnmE | 0.0 | central tRNA-modifying GTPase | 82.02 | 99.56 | ABP90420 |
| ODFFANLH_42 | 69388 | 67496 | PepO | 0.0 | endopeptidase | 80.03 | 100.00 | ABF32980 |
| ODFFANLH_1 | 134984 | 134094 | bglB | 3.67e-178 | putative phospho--glucosidase | 88.55 | 99.66 | AAK33487 |
| ODFFANLH_10 | 8006 | 8863 | metF | 1.22e-166 | methionine biosynthesis enzymes | 86.36 | 99.31 | AAK74739 |
| ODFFANLH_4 | 41562 | 42500 | SP_0676 | 1.44e-157 | transcription facot | 81.15 | 97.20 | AAK74821 |
| ODFFANLH_23 | 24410 | 23706 | covR | 2.99e-131 | responder protein | 84.68 | 100.00 | AAK71319 |
| ODFFANLH_23 | 24410 | 23706 | walR | 2.14e-121 | DNA-binding response regulator | 80.85 | 100.00 | ANC99504 |
| ODFFANLH_39 | 7667 | 6981 | CovR | 4.94e-119 | serves to repress GAS virulence factor-encoding genes | 80.79 | 100.00 | ACE75886 |
| ODFFANLH_10 | 14693 | 15361 | CiaR | 6.03e-119 | two-component response regulator | 84.31 | 99.55 | AAK74935 |
| ODFFANLH_10 | 14693 | 15364 | ciaR | 7.27e-117 | two component system response regulator | 82.14 | 99.12 | AIK75708 |
| ODFFANLH_13 | 21900 | 22295 | SpxA2 | 4.45e-76 | transcriptional regulator | 90.91 | 100.00 | ERL21461 |
| ODFFANLH_6 | 13672 | 13959 | spr0479 | 2.98e-49 | essential gene | 86.46 | 98.97 | AAK99283 |
| ODFFANLH_1 | 237435 | 237181 | spr1327 | 4.45e-45 | essential gene | 95.29 | 100.00 | AAL00131 |
| ODFFANLH_40 | 75552 | 75289 | spr0175 | 3.95e-42 | pathogenitcity related | 84.09 | 100.00 | AAK98979 |
| ODFFANLH_40 | 74725 | 74459 | spr0177 | 6.98e-34 | essential gene | 84.27 | 88.12 | AAK98981 |
| ODFFANLH_3 | 62729 | 62229 | RopE (M5005_Spy_1611) | 1.78e-76 | probable DNA-directed RNA polymerase subunit delta | 81.44 | 87.43 | AAK34603 |
| ODFFANLH_12 | 55572 | 57869 | PFL (B9H01_RS01125) | 0.0 | formate C-acetyltransferase | 82.94 | 98.08 | MYN69560 |
| ODFFANLH_42 | 54928 | 53909 | ilvC (SPD_0406) | 0.0 | ketol-acid reductoisomerase (NADP(+)) | 96.18 | 100.00 | ABJ55451 |
BLASTX v2.16.0 (Database: PHI base v4.16, May. 2024 release)
Plasmid
PlasmidFinder
| Query ID | Begin | End | Plasmid | Query / Template | Identity | Accession no. |
|---|---|---|---|---|---|---|
| ODFFANLH_24 | 943 | 1890 | rep37 | 950 / 948 | 94.84 | AF177167 |
PlasmidFinder v 2.1.6 (Database: plasmidfinder_db v 2.2.0 , Nov. 2024 release)
PlasmidHunter
| Query ID | Prediction | Chromosome | Plasmid |
|---|---|---|---|
| ODFFANLH_1 | 0.0 | 1.0 | 0.0 |
| ODFFANLH_2 | 0.0 | 1.0 | 0.0 |
| ODFFANLH_3 | 0.0 | 1.0 | 0.0 |
| ODFFANLH_4 | 0.0 | 1.0 | 0.0 |
| ODFFANLH_5 | 0.0 | 1.0 | 0.0 |
| ODFFANLH_6 | 0.0 | 1.0 | 0.0 |
| ODFFANLH_7 | 0.0 | 1.0 | 0.0 |
| ODFFANLH_8 | 0.0 | 1.0 | 0.0 |
| ODFFANLH_9 | 0.0 | 1.0 | 0.0 |
| ODFFANLH_10 | 0.0 | 1.0 | 0.0 |
| ODFFANLH_11 | 0.0 | 1.0 | 0.0 |
| ODFFANLH_12 | 0.0 | 1.0 | 0.0 |
| ODFFANLH_13 | 0.0 | 1.0 | 0.0 |
| ODFFANLH_14 | 0.0 | 1.0 | 0.0 |
| ODFFANLH_15 | 0.0 | 1.0 | 0.0 |
| ODFFANLH_16 | 0.0 | 1.0 | 0.0 |
| ODFFANLH_17 | 0.0 | 1.0 | 0.0 |
| ODFFANLH_18 | 0.0 | 1.0 | 0.0 |
| ODFFANLH_20 | 1.0 | 0.0 | 1.0 |
| ODFFANLH_21 | 0.0 | 1.0 | 0.0 |
| ODFFANLH_22 | 0.0 | 1.0 | 0.0 |
| ODFFANLH_23 | 0.0 | 1.0 | 0.0 |
| ODFFANLH_24 | 1.0 | 0.0 | 1.0 |
| ODFFANLH_25 | 0.0 | 1.0 | 0.0 |
| ODFFANLH_26 | 0.0 | 1.0 | 0.0 |
| ODFFANLH_27 | 1.0 | 0.0 | 1.0 |
| ODFFANLH_28 | 1.0 | 0.0 | 1.0 |
| ODFFANLH_29 | 0.0 | 1.0 | 0.0 |
| ODFFANLH_30 | 0.0 | 1.0 | 0.0 |
| ODFFANLH_31 | 0.0 | 1.0 | 0.0 |
| ODFFANLH_32 | 0.0 | 1.0 | 0.0 |
| ODFFANLH_34 | 0.0 | 1.0 | 0.0 |
| ODFFANLH_38 | 0.0 | 1.0 | 0.0 |
| ODFFANLH_39 | 0.0 | 1.0 | 0.0 |
| ODFFANLH_40 | 0.0 | 1.0 | 0.0 |
| ODFFANLH_41 | 0.0 | 1.0 | 0.0 |
| ODFFANLH_42 | 0.0 | 1.0 | 0.0 |
PlasmidHunter v 1.4.5 (Database: May. 2024 release)
Prophage
Phigaro
| Query ID | Begin | End | Transposable | Taxonomy | pVOGs |
|---|---|---|---|---|---|
| No hit found | |||||
Phigaro v2.4.0 (Database: Jan. 2024 release)