Probiotic potential risk score
| ARGs | VFs | PGs | PPRS |
|---|---|---|---|
| 0 | 16 | 35 | 38.48 |
PPRS is classified as low-risk (≤4), medium-risk (4-6), and high-risk (≥6).
Antibiotic resistance genes
Comprehensive Antibiotic Resistance Database (CARD)
| Query ID | Begin | End | ARO name | ARO accession | CARD name | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
RGI v6.0.3 (Database: CARD Variants v4.0.2, Nov. 2023 release)
ResFinder
| Query ID | Begin | End | Resistance gene | Phenotype | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|
| No hit found | |||||||
ResFinder v4.6.0 (Database: resfinder_db, Aug. 2024 release)
AMRFinderPlus
| Query ID | Begin | End | Gene symbol | Sequence name | Method | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
AMRFinderPlus v4.0.3 (Database: Oct. 2024 release)
Virulence factors
Virulence Factor Database (VFDB)
| Query ID | qstart | qend | Gene name | e-value | VF name | VF category | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|---|
| OJCAFAII_10 | 13420 | 14151 | STER_RS05315 | 0.0 | Capsule | Immune modulation | 94.81 | 100.00 | WP_011681176 |
| OJCAFAII_10 | 13420 | 14151 | STU_RS14645 | 0.0 | Capsule | Immune modulation | 94.54 | 100.00 | WP_011226048 |
| OJCAFAII_22 | 72638 | 73489 | rfbD | 0.0 | Capsule | Immune modulation | 94.48 | 100.00 | WP_014621820 |
| OJCAFAII_22 | 76214 | 76930 | STER_RS07085 | 0.0 | Capsule | Immune modulation | 94.42 | 100.00 | WP_011681442 |
| OJCAFAII_10 | 13420 | 14151 | STR_RS05260 | 0.0 | Capsule | Immune modulation | 94.13 | 100.00 | WP_011227248 |
| OJCAFAII_22 | 77276 | 78046 | STER_RS07075 | 0.0 | Capsule | Immune modulation | 92.35 | 99.23 | WP_011681440 |
| OJCAFAII_52 | 59990 | 60583 | STR_RS05880 | 0.0 | Capsule | Immune modulation | 91.08 | 100.00 | WP_011226149 |
| OJCAFAII_44 | 91654 | 93312 | fbp54 | 0.0 | FBPs | Adherence | 90.96 | 99.94 | WP_011227179 |
| OJCAFAII_10 | 14152 | 15612 | STER_RS05320 | 0.0 | Capsule | Immune modulation | 90.92 | 99.86 | WP_011681177 |
| OJCAFAII_52 | 59990 | 60583 | STER_RS06030 | 0.0 | Capsule | Immune modulation | 90.91 | 100.00 | WP_011226149 |
| OJCAFAII_52 | 59990 | 60583 | STU_RS15260 | 0.0 | Capsule | Immune modulation | 90.91 | 100.00 | WP_011226149 |
| OJCAFAII_10 | 14152 | 15612 | STU_RS14650 | 0.0 | Capsule | Immune modulation | 90.78 | 100.00 | WP_011226049 |
| OJCAFAII_21 | 7680 | 8519 | cbpD | 0.0 | Autolysin | Exoenzyme | 90.36 | 100.00 | WP_011226733 |
| OJCAFAII_10 | 14152 | 15612 | STR_RS05265 | 0.0 | Capsule | Immune modulation | 89.97 | 100.00 | WP_041827043 |
| OJCAFAII_10 | 12719 | 13411 | STU_RS14640 | 0.0 | Capsule | Immune modulation | 89.90 | 100.00 | WP_011226047 |
| OJCAFAII_10 | 12719 | 13411 | STR_RS05255 | 0.0 | Capsule | Immune modulation | 89.61 | 100.00 | WP_011227247 |
| OJCAFAII_10 | 12719 | 13411 | STER_RS05310 | 0.0 | Capsule | Immune modulation | 89.47 | 100.00 | WP_011681175 |
| OJCAFAII_54 | 31266 | 32569 | eno | 0.0 | Streptococcal enolase | Exoenzyme | 88.17 | 99.54 | WP_000022832 |
| OJCAFAII_11 | 14381 | 15394 | plr/gapA | 0.0 | Streptococcal plasmin receptor/GAPDH | Adherence | 85.67 | 99.90 | WP_002986042 |
| OJCAFAII_13 | 3665 | 4426 | srtA | 0.0 | Sortase A | Exoenzyme | 83.88 | 99.87 | - |
| OJCAFAII_52 | 60853 | 61899 | rfbB | 0.0 | Capsule | Immune modulation | 83.49 | 99.90 | WP_002263087 |
| OJCAFAII_53 | 89125 | 90408 | tig/ropA | 0.0 | Trigger factor | Stress survival | 80.84 | 99.61 | WP_000107753 |
| OJCAFAII_52 | 59121 | 59990 | rfbA | 0.0 | Capsule | Immune modulation | 80.28 | 99.77 | WP_002904719 |
| OJCAFAII_10 | 12039 | 12709 | STU_RS14635 | 2.61e-148 | Capsule | Immune modulation | 80.98 | 90.28 | WP_011226046 |
| OJCAFAII_10 | 12039 | 12709 | STER_RS05305 | 1.22e-146 | Capsule | Immune modulation | 80.83 | 90.28 | WP_011681174 |
| OJCAFAII_10 | 12107 | 12709 | STR_RS05250 | 1.23e-136 | Capsule | Immune modulation | 81.46 | 80.13 | WP_011227246 |
BLASTN v2.16.0 (Database: VFDB, Dec. 2024 release)
VirulenceFinder
| Query ID | Begin | End | Database | Virulence factor | Protein function | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
VirulenceFinder v2.0. 4 (Database: virulencefinder_db, Feb . 2024 release)
Pathogenic genes
PHI-base
| Query ID | qstart | qend | Gene name | e-value | Function | Identity | Coverage | Gene ID |
|---|---|---|---|---|---|---|---|---|
| OJCAFAII_13 | 7116 | 8099 | ldh(Sp_1220) | 0.0 | L-lactate dehydrogenase | 96.95 | 100.00 | AAK75326 |
| OJCAFAII_20 | 5164 | 6237 | MntE | 0.0 | manganese homeostasis | 96.09 | 99.72 | ABF32167 |
| OJCAFAII_11 | 141351 | 139045 | pfl2(Sp_0459) | 0.0 | formate acetyltransferase | 94.28 | 99.22 | AAK74619 |
| OJCAFAII_33 | 93743 | 95224 | SPD_0310 | 0.0 | UPF0371 protein SPD_0310 | 93.12 | 100.00 | ABJ54480 |
| OJCAFAII_20 | 24222 | 26468 | metE | 0.0 | methionine biosynthesis enzymes | 93.06 | 100.00 | AAK74738 |
| OJCAFAII_6 | 46993 | 46025 | spr0084 | 0.0 | pathogenitcity related | 92.88 | 98.48 | AAK98888 |
| OJCAFAII_21 | 23124 | 22153 | prsA2 | 0.0 | ribose-phosphate pyrophosphokinase | 91.67 | 100.00 | ABF36968 |
| OJCAFAII_33 | 7161 | 688 | PrtA | 0.0 | serine protease | 91.30 | 100.61 | ABJ55268 |
| OJCAFAII_52 | 34295 | 36025 | ptsI | 0.0 | phosphoenolpyruvate-protein phosphotransferase | 89.95 | 100.00 | AAK34199 |
| OJCAFAII_11 | 278713 | 279864 | potA | 0.0 | ABC transporter ATP-binding protein-spermidine/putrescine transport | 89.32 | 99.74 | AAL00050 |
| OJCAFAII_22 | 58936 | 60924 | uvrB | 0.0 | excinuclease ABC, B subunit | 89.29 | 100.00 | AE014259_2 |
| OJCAFAII_15 | 25880 | 27358 | IMPDH | 0.0 | inosine-5'-monophosphate dehydrogenase | 87.83 | 100.00 | ADE32434 |
| OJCAFAII_54 | 32569 | 31268 | Eno | 0.0 | enolase | 86.44 | 99.77 | ABP90468 |
| OJCAFAII_4 | 57065 | 55173 | gidA | 0.0 | tRNA uridine 5-carboxymethylaminomethyl modification enzyme | 85.74 | 98.90 | ABP91129 |
| OJCAFAII_27 | 14921 | 16012 | recA | 0.0 | DNA recombination and repair | 84.91 | 95.36 | AAL00560 |
| OJCAFAII_50 | 2038 | 329 | PGM | 0.0 | phosphoglucomutase | 84.59 | 99.65 | ACH87041 |
| OJCAFAII_51 | 78039 | 77029 | pdh | 0.0 | pyruvate dehydrogenase | 83.38 | 99.70 | ABP91006 |
| OJCAFAII_44 | 77728 | 79089 | mnmE | 0.0 | central tRNA-modifying GTPase | 82.89 | 99.56 | ABP90420 |
| OJCAFAII_54 | 46983 | 46093 | bglB | 8.74e-179 | putative phospho--glucosidase | 87.88 | 99.66 | AAK33487 |
| OJCAFAII_20 | 26658 | 27515 | metF | 1.17e-169 | methionine biosynthesis enzymes | 87.06 | 99.31 | AAK74739 |
| OJCAFAII_50 | 43578 | 42640 | SP_0676 | 4.98e-169 | transcription facot | 81.47 | 97.20 | AAK74821 |
| OJCAFAII_22 | 72638 | 73459 | GacA | 7.13e-148 | dTDP-4-dehydrorhamnose reductas | 80.66 | 96.48 | AAZ51220 |
| OJCAFAII_40 | 3964 | 3260 | covR | 8.01e-130 | responder protein | 85.53 | 100.00 | AAK71319 |
| OJCAFAII_33 | 25140 | 24469 | rr01 | 2.65e-127 | response regulator | 84.82 | 99.56 | CAB54566 |
| OJCAFAII_50 | 6704 | 7375 | ciaR | 1.06e-125 | two component system response regulator | 86.16 | 99.12 | AIK75708 |
| OJCAFAII_50 | 6704 | 7372 | CiaR | 1.96e-125 | two-component response regulator | 87.44 | 99.55 | AAK74935 |
| OJCAFAII_40 | 3964 | 3260 | walR | 3.98e-123 | DNA-binding response regulator | 82.13 | 100.00 | ANC99504 |
| OJCAFAII_3 | 27494 | 28180 | CovR | 5.35e-121 | serves to repress GAS virulence factor-encoding genes | 82.10 | 100.00 | ACE75886 |
| OJCAFAII_27 | 16186 | 16581 | SpxA2 | 1.65e-76 | transcriptional regulator | 91.67 | 100.00 | ERL21461 |
| OJCAFAII_44 | 66270 | 65869 | SpxA1 | 7.41e-70 | transcriptional regulator | 82.09 | 100.00 | ERL19273 |
| OJCAFAII_25 | 6825 | 6412 | GrpE | 1.49e-68 | protein grpE | 81.88 | 80.59 | ABP89267 |
| OJCAFAII_3 | 50697 | 50984 | spr0479 | 3.51e-48 | essential gene | 85.42 | 98.97 | AAK99283 |
| OJCAFAII_12 | 16864 | 17118 | spr1327 | 1.35e-46 | essential gene | 94.12 | 100.00 | AAL00131 |
| OJCAFAII_4 | 7412 | 7675 | spr0175 | 3.27e-43 | pathogenitcity related | 85.23 | 100.00 | AAK98979 |
| OJCAFAII_4 | 8237 | 8503 | spr0177 | 7.26e-42 | essential gene | 83.15 | 88.12 | AAK98981 |
| OJCAFAII_53 | 88958 | 88467 | RopE (M5005_Spy_1611) | 4.45e-73 | probable DNA-directed RNA polymerase subunit delta | 83.54 | 85.86 | AAK34603 |
| OJCAFAII_11 | 141351 | 139051 | PFL (B9H01_RS01125) | 0.0 | formate C-acetyltransferase | 82.97 | 98.08 | MYN69560 |
| OJCAFAII_51 | 41363 | 42382 | ilvC (SPD_0406) | 0.0 | ketol-acid reductoisomerase (NADP(+)) | 85.88 | 100.00 | ABJ55451 |
| OJCAFAII_44 | 106297 | 105758 | pnuC | 1.52e-94 | NAD salvage pathway importer | 83.89 | 66.91 | AAK75931 |
BLASTX v2.16.0 (Database: PHI base v4.16, May. 2024 release)
Plasmid
PlasmidFinder
| Query ID | Begin | End | Plasmid | Query / Template | Identity | Accession no. |
|---|---|---|---|---|---|---|
| No hit found | ||||||
PlasmidFinder v 2.1.6 (Database: plasmidfinder_db v 2.2.0 , Nov. 2024 release)
PlasmidHunter
| Query ID | Prediction | Chromosome | Plasmid |
|---|---|---|---|
| OJCAFAII_1 | 0.0 | 1.0 | 0.0 |
| OJCAFAII_2 | 0.0 | 1.0 | 0.0 |
| OJCAFAII_3 | 0.0 | 1.0 | 0.0 |
| OJCAFAII_4 | 0.0 | 1.0 | 0.0 |
| OJCAFAII_5 | 0.0 | 1.0 | 0.0 |
| OJCAFAII_6 | 0.0 | 1.0 | 0.0 |
| OJCAFAII_7 | 1.0 | 0.0 | 1.0 |
| OJCAFAII_8 | 1.0 | 0.0 | 1.0 |
| OJCAFAII_9 | 0.0 | 1.0 | 0.0 |
| OJCAFAII_10 | 0.0 | 1.0 | 0.0 |
| OJCAFAII_11 | 0.0 | 1.0 | 0.0 |
| OJCAFAII_12 | 0.0 | 1.0 | 0.0 |
| OJCAFAII_13 | 0.0 | 1.0 | 0.0 |
| OJCAFAII_14 | 0.0 | 1.0 | 0.0 |
| OJCAFAII_15 | 0.0 | 1.0 | 0.0 |
| OJCAFAII_16 | 0.0 | 1.0 | 0.0 |
| OJCAFAII_17 | 0.0 | 1.0 | 0.0 |
| OJCAFAII_18 | 1.0 | 0.0 | 1.0 |
| OJCAFAII_19 | 0.0 | 1.0 | 0.0 |
| OJCAFAII_20 | 0.0 | 1.0 | 0.0 |
| OJCAFAII_21 | 0.0 | 1.0 | 0.0 |
| OJCAFAII_22 | 0.0 | 1.0 | 0.0 |
| OJCAFAII_23 | 0.0 | 1.0 | 0.0 |
| OJCAFAII_24 | 0.0 | 1.0 | 0.0 |
| OJCAFAII_25 | 0.0 | 1.0 | 0.0 |
| OJCAFAII_26 | 0.0 | 1.0 | 0.0 |
| OJCAFAII_27 | 0.0 | 1.0 | 0.0 |
| OJCAFAII_28 | 1.0 | 0.0 | 1.0 |
| OJCAFAII_29 | 0.0 | 1.0 | 0.0 |
| OJCAFAII_30 | 1.0 | 0.0 | 1.0 |
| OJCAFAII_31 | 1.0 | 0.0 | 1.0 |
| OJCAFAII_32 | 0.0 | 1.0 | 0.0 |
| OJCAFAII_33 | 0.0 | 1.0 | 0.0 |
| OJCAFAII_34 | 1.0 | 0.0 | 1.0 |
| OJCAFAII_35 | 0.0 | 1.0 | 0.0 |
| OJCAFAII_36 | 0.0 | 1.0 | 0.0 |
| OJCAFAII_37 | 0.0 | 1.0 | 0.0 |
| OJCAFAII_40 | 0.0 | 1.0 | 0.0 |
| OJCAFAII_41 | 0.0 | 1.0 | 0.0 |
| OJCAFAII_42 | 1.0 | 0.0 | 1.0 |
| OJCAFAII_43 | 0.0 | 1.0 | 0.0 |
| OJCAFAII_44 | 0.0 | 1.0 | 0.0 |
| OJCAFAII_45 | 0.0 | 1.0 | 0.0 |
| OJCAFAII_46 | 0.0 | 1.0 | 0.0 |
| OJCAFAII_48 | 0.0 | 1.0 | 0.0 |
| OJCAFAII_49 | 0.0 | 1.0 | 0.0 |
| OJCAFAII_50 | 0.0 | 1.0 | 0.0 |
| OJCAFAII_51 | 0.0 | 1.0 | 0.0 |
| OJCAFAII_52 | 0.0 | 1.0 | 0.0 |
| OJCAFAII_53 | 0.0 | 1.0 | 0.0 |
| OJCAFAII_54 | 0.0 | 1.0 | 0.0 |
PlasmidHunter v 1.4.5 (Database: May. 2024 release)
Prophage
Phigaro
| Query ID | Begin | End | Transposable | Taxonomy | pVOGs |
|---|---|---|---|---|---|
| No hit found | |||||
Phigaro v2.4.0 (Database: Jan. 2024 release)