Probiotic potential risk score
| ARGs | VFs | PGs | PPRS |
|---|---|---|---|
| 0 | 16 | 36 | 39.40 |
PPRS is classified as low-risk (≤4), medium-risk (4-6), and high-risk (≥6).
Antibiotic resistance genes
Comprehensive Antibiotic Resistance Database (CARD)
| Query ID | Begin | End | ARO name | ARO accession | CARD name | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
RGI v6.0.3 (Database: CARD Variants v4.0.2, Nov. 2023 release)
ResFinder
| Query ID | Begin | End | Resistance gene | Phenotype | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|
| No hit found | |||||||
ResFinder v4.6.0 (Database: resfinder_db, Aug. 2024 release)
AMRFinderPlus
| Query ID | Begin | End | Gene symbol | Sequence name | Method | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
AMRFinderPlus v4.0.3 (Database: Oct. 2024 release)
Virulence factors
Virulence Factor Database (VFDB)
| Query ID | qstart | qend | Gene name | e-value | VF name | VF category | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|---|
| KGIDHJJC_3 | 11366 | 12097 | STR_RS05260 | 0.0 | Capsule | Immune modulation | 94.54 | 100.00 | WP_011227248 |
| KGIDHJJC_45 | 117511 | 118362 | rfbD | 0.0 | Capsule | Immune modulation | 94.48 | 100.00 | WP_014621820 |
| KGIDHJJC_45 | 121087 | 121803 | STER_RS07085 | 0.0 | Capsule | Immune modulation | 94.42 | 100.00 | WP_011681442 |
| KGIDHJJC_3 | 11366 | 12097 | STU_RS14645 | 0.0 | Capsule | Immune modulation | 93.85 | 100.00 | WP_011226048 |
| KGIDHJJC_3 | 11366 | 12097 | STER_RS05315 | 0.0 | Capsule | Immune modulation | 93.58 | 100.00 | WP_011681176 |
| KGIDHJJC_45 | 122149 | 122919 | STER_RS07075 | 0.0 | Capsule | Immune modulation | 92.48 | 99.23 | WP_011681440 |
| KGIDHJJC_3 | 9905 | 11365 | STER_RS05320 | 0.0 | Capsule | Immune modulation | 91.26 | 99.86 | WP_011681177 |
| KGIDHJJC_22 | 137642 | 138235 | STR_RS05880 | 0.0 | Capsule | Immune modulation | 91.08 | 100.00 | WP_011226149 |
| KGIDHJJC_22 | 137642 | 138235 | STER_RS06030 | 0.0 | Capsule | Immune modulation | 90.91 | 100.00 | WP_011226149 |
| KGIDHJJC_22 | 137642 | 138235 | STU_RS15260 | 0.0 | Capsule | Immune modulation | 90.91 | 100.00 | WP_011226149 |
| KGIDHJJC_3 | 9905 | 11365 | STU_RS14650 | 0.0 | Capsule | Immune modulation | 90.65 | 100.00 | WP_011226049 |
| KGIDHJJC_11 | 21385 | 23042 | fbp54 | 0.0 | FBPs | Adherence | 90.36 | 99.88 | WP_011227179 |
| KGIDHJJC_3 | 9905 | 11365 | STR_RS05265 | 0.0 | Capsule | Immune modulation | 89.97 | 100.00 | WP_041827043 |
| KGIDHJJC_3 | 12106 | 12798 | STU_RS14640 | 0.0 | Capsule | Immune modulation | 89.90 | 100.00 | WP_011226047 |
| KGIDHJJC_3 | 12106 | 12798 | STR_RS05255 | 0.0 | Capsule | Immune modulation | 89.61 | 100.00 | WP_011227247 |
| KGIDHJJC_3 | 12106 | 12798 | STER_RS05310 | 0.0 | Capsule | Immune modulation | 89.47 | 100.00 | WP_011681175 |
| KGIDHJJC_45 | 30317 | 31156 | cbpD | 0.0 | Autolysin | Exoenzyme | 89.06 | 99.88 | WP_011226733 |
| KGIDHJJC_47 | 38295 | 39598 | eno | 0.0 | Streptococcal enolase | Exoenzyme | 87.25 | 99.54 | WP_000022832 |
| KGIDHJJC_4 | 36792 | 37802 | plr/gapA | 0.0 | Streptococcal plasmin receptor/GAPDH | Adherence | 86.28 | 99.80 | WP_002986042 |
| KGIDHJJC_11 | 176473 | 177234 | srtA | 0.0 | Sortase A | Exoenzyme | 83.88 | 99.87 | - |
| KGIDHJJC_22 | 138505 | 139551 | rfbB | 0.0 | Capsule | Immune modulation | 83.59 | 99.90 | WP_002263087 |
| KGIDHJJC_33 | 1785 | 3068 | tig/ropA | 0.0 | Trigger factor | Stress survival | 80.68 | 99.61 | WP_000107753 |
| KGIDHJJC_22 | 136773 | 137642 | rfbA | 0.0 | Capsule | Immune modulation | 80.28 | 99.77 | WP_002904719 |
| KGIDHJJC_3 | 12808 | 13478 | STU_RS14635 | 6.96e-150 | Capsule | Immune modulation | 81.13 | 90.28 | WP_011226046 |
| KGIDHJJC_3 | 12808 | 13478 | STER_RS05305 | 3.24e-148 | Capsule | Immune modulation | 80.98 | 90.28 | WP_011681174 |
| KGIDHJJC_3 | 12808 | 13478 | STR_RS05250 | 3.28e-138 | Capsule | Immune modulation | 80.09 | 89.20 | WP_011227246 |
BLASTN v2.16.0 (Database: VFDB, Dec. 2024 release)
VirulenceFinder
| Query ID | Begin | End | Database | Virulence factor | Protein function | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
VirulenceFinder v2.0. 4 (Database: virulencefinder_db, Feb . 2024 release)
Pathogenic genes
PHI-base
| Query ID | qstart | qend | Gene name | e-value | Function | Identity | Coverage | Gene ID |
|---|---|---|---|---|---|---|---|---|
| KGIDHJJC_11 | 179924 | 180907 | ldh(Sp_1220) | 0.0 | L-lactate dehydrogenase | 96.95 | 100.00 | AAK75326 |
| KGIDHJJC_11 | 168335 | 167262 | MntE | 0.0 | manganese homeostasis | 96.09 | 99.72 | ABF32167 |
| KGIDHJJC_43 | 9285 | 6979 | pfl2(Sp_0459) | 0.0 | formate acetyltransferase | 94.41 | 99.22 | AAK74619 |
| KGIDHJJC_11 | 321915 | 323396 | SPD_0310 | 0.0 | UPF0371 protein SPD_0310 | 93.12 | 100.00 | ABJ54480 |
| KGIDHJJC_5 | 36813 | 35845 | spr0084 | 0.0 | pathogenitcity related | 92.88 | 98.48 | AAK98888 |
| KGIDHJJC_11 | 148216 | 145970 | metE | 0.0 | methionine biosynthesis enzymes | 92.66 | 100.00 | AAK74738 |
| KGIDHJJC_8 | 25522 | 24551 | prsA2 | 0.0 | ribose-phosphate pyrophosphokinase | 91.67 | 100.00 | ABF36968 |
| KGIDHJJC_11 | 239106 | 232633 | PrtA | 0.0 | serine protease | 91.30 | 100.61 | ABJ55268 |
| KGIDHJJC_22 | 111397 | 113127 | ptsI | 0.0 | phosphoenolpyruvate-protein phosphotransferase | 90.12 | 100.00 | AAK34199 |
| KGIDHJJC_45 | 103809 | 105797 | uvrB | 0.0 | excinuclease ABC, B subunit | 89.59 | 100.00 | AE014259_2 |
| KGIDHJJC_43 | 138792 | 139943 | potA | 0.0 | ABC transporter ATP-binding protein-spermidine/putrescine transport | 89.58 | 99.74 | AAL00050 |
| KGIDHJJC_2 | 54395 | 52917 | IMPDH | 0.0 | inosine-5'-monophosphate dehydrogenase | 87.83 | 100.00 | ADE32434 |
| KGIDHJJC_47 | 39598 | 38297 | Eno | 0.0 | enolase | 86.44 | 99.77 | ABP90468 |
| KGIDHJJC_2 | 38615 | 36723 | gidA | 0.0 | tRNA uridine 5-carboxymethylaminomethyl modification enzyme | 85.42 | 98.90 | ABP91129 |
| KGIDHJJC_11 | 143052 | 144761 | PGM | 0.0 | phosphoglucomutase | 84.76 | 99.65 | ACH87041 |
| KGIDHJJC_18 | 12592 | 13683 | recA | 0.0 | DNA recombination and repair | 84.64 | 95.36 | AAL00560 |
| KGIDHJJC_46 | 29814 | 30824 | pdh | 0.0 | pyruvate dehydrogenase | 83.09 | 99.70 | ABP91006 |
| KGIDHJJC_11 | 5822 | 7183 | mnmE | 0.0 | central tRNA-modifying GTPase | 82.89 | 99.56 | ABP90420 |
| KGIDHJJC_47 | 54005 | 53115 | bglB | 1.02e-177 | putative phospho--glucosidase | 87.20 | 99.66 | AAK33487 |
| KGIDHJJC_11 | 145780 | 144923 | metF | 1.12e-169 | methionine biosynthesis enzymes | 87.76 | 99.31 | AAK74739 |
| KGIDHJJC_11 | 101489 | 102439 | SP_0676 | 1.62e-169 | transcription facot | 81.39 | 98.45 | AAK74821 |
| KGIDHJJC_22 | 74512 | 73655 | mtsA | 6.61e-152 | substrate-binding lipoprotein of manganese transporter | 80.49 | 92.86 | AIK76191 |
| KGIDHJJC_45 | 117511 | 118332 | GacA | 3.99e-148 | dTDP-4-dehydrorhamnose reductas | 80.66 | 96.48 | AAZ51220 |
| KGIDHJJC_24 | 3903 | 3199 | covR | 1.38e-128 | responder protein | 85.53 | 100.00 | AAK71319 |
| KGIDHJJC_11 | 260925 | 260254 | rr01 | 7.24e-127 | response regulator | 84.82 | 99.56 | CAB54566 |
| KGIDHJJC_11 | 138375 | 137704 | ciaR | 3.23e-125 | two component system response regulator | 86.16 | 99.12 | AIK75708 |
| KGIDHJJC_11 | 138375 | 137707 | CiaR | 5.98e-125 | two-component response regulator | 87.44 | 99.55 | AAK74935 |
| KGIDHJJC_24 | 3903 | 3199 | walR | 4.03e-122 | DNA-binding response regulator | 82.13 | 100.00 | ANC99504 |
| KGIDHJJC_33 | 156929 | 157615 | CovR | 1.62e-120 | serves to repress GAS virulence factor-encoding genes | 82.10 | 100.00 | ACE75886 |
| KGIDHJJC_18 | 13856 | 14251 | SpxA2 | 1.41e-76 | transcriptional regulator | 91.67 | 100.00 | ERL21461 |
| KGIDHJJC_9 | 24200 | 23799 | SpxA1 | 1.90e-70 | transcriptional regulator | 82.09 | 100.00 | ERL19273 |
| KGIDHJJC_6 | 6237 | 5851 | GrpE | 1.16e-64 | protein grpE | 82.95 | 75.29 | ABP89267 |
| KGIDHJJC_33 | 180133 | 180420 | spr0479 | 5.12e-48 | essential gene | 85.42 | 98.97 | AAK99283 |
| KGIDHJJC_15 | 17076 | 17330 | spr1327 | 8.87e-46 | essential gene | 92.94 | 100.00 | AAL00131 |
| KGIDHJJC_2 | 7442 | 7705 | spr0175 | 3.18e-43 | pathogenitcity related | 85.23 | 100.00 | AAK98979 |
| KGIDHJJC_2 | 8267 | 8533 | spr0177 | 7.07e-42 | essential gene | 83.15 | 88.12 | AAK98981 |
| KGIDHJJC_33 | 3235 | 3726 | RopE (M5005_Spy_1611) | 9.36e-73 | probable DNA-directed RNA polymerase subunit delta | 82.93 | 85.86 | AAK34603 |
| KGIDHJJC_43 | 9285 | 6985 | PFL (B9H01_RS01125) | 0.0 | formate C-acetyltransferase | 83.22 | 98.08 | MYN69560 |
| KGIDHJJC_46 | 65954 | 64935 | ilvC (SPD_0406) | 0.0 | ketol-acid reductoisomerase (NADP(+)) | 85.88 | 100.00 | ABJ55451 |
BLASTX v2.16.0 (Database: PHI base v4.16, May. 2024 release)
Plasmid
PlasmidFinder
| Query ID | Begin | End | Plasmid | Query / Template | Identity | Accession no. |
|---|---|---|---|---|---|---|
| No hit found | ||||||
PlasmidFinder v 2.1.6 (Database: plasmidfinder_db v 2.2.0 , Nov. 2024 release)
PlasmidHunter
| Query ID | Prediction | Chromosome | Plasmid |
|---|---|---|---|
| KGIDHJJC_1 | 0.0 | 1.0 | 0.0 |
| KGIDHJJC_2 | 0.0 | 1.0 | 0.0 |
| KGIDHJJC_3 | 0.0 | 1.0 | 0.0 |
| KGIDHJJC_4 | 0.0 | 1.0 | 0.0 |
| KGIDHJJC_5 | 0.0 | 1.0 | 0.0 |
| KGIDHJJC_6 | 0.0 | 1.0 | 0.0 |
| KGIDHJJC_7 | 0.0 | 1.0 | 0.0 |
| KGIDHJJC_8 | 0.0 | 1.0 | 0.0 |
| KGIDHJJC_9 | 0.0 | 1.0 | 0.0 |
| KGIDHJJC_10 | 0.0 | 1.0 | 0.0 |
| KGIDHJJC_11 | 0.0 | 1.0 | 0.0 |
| KGIDHJJC_12 | 0.0 | 1.0 | 0.0 |
| KGIDHJJC_13 | 0.0 | 1.0 | 0.0 |
| KGIDHJJC_14 | 0.0 | 1.0 | 0.0 |
| KGIDHJJC_15 | 0.0 | 1.0 | 0.0 |
| KGIDHJJC_16 | 0.0 | 1.0 | 0.0 |
| KGIDHJJC_17 | 0.0 | 1.0 | 0.0 |
| KGIDHJJC_18 | 0.0 | 1.0 | 0.0 |
| KGIDHJJC_19 | 0.0 | 1.0 | 0.0 |
| KGIDHJJC_20 | 0.0 | 1.0 | 0.0 |
| KGIDHJJC_21 | 1.0 | 0.0 | 1.0 |
| KGIDHJJC_22 | 0.0 | 1.0 | 0.0 |
| KGIDHJJC_23 | 0.0 | 1.0 | 0.0 |
| KGIDHJJC_24 | 0.0 | 1.0 | 0.0 |
| KGIDHJJC_25 | 0.0 | 1.0 | 0.0 |
| KGIDHJJC_26 | 1.0 | 0.0 | 1.0 |
| KGIDHJJC_28 | 0.0 | 1.0 | 0.0 |
| KGIDHJJC_29 | 0.0 | 1.0 | 0.0 |
| KGIDHJJC_30 | 0.0 | 1.0 | 0.0 |
| KGIDHJJC_32 | 0.0 | 1.0 | 0.0 |
| KGIDHJJC_33 | 0.0 | 1.0 | 0.0 |
| KGIDHJJC_34 | 0.0 | 1.0 | 0.0 |
| KGIDHJJC_35 | 0.0 | 1.0 | 0.0 |
| KGIDHJJC_36 | 0.0 | 1.0 | 0.0 |
| KGIDHJJC_37 | 0.0 | 1.0 | 0.0 |
| KGIDHJJC_38 | 0.0 | 1.0 | 0.0 |
| KGIDHJJC_39 | 0.0 | 1.0 | 0.0 |
| KGIDHJJC_40 | 0.0 | 1.0 | 0.0 |
| KGIDHJJC_41 | 1.0 | 0.0 | 1.0 |
| KGIDHJJC_42 | 0.0 | 1.0 | 0.0 |
| KGIDHJJC_43 | 0.0 | 1.0 | 0.0 |
| KGIDHJJC_44 | 0.0 | 1.0 | 0.0 |
| KGIDHJJC_45 | 0.0 | 1.0 | 0.0 |
| KGIDHJJC_46 | 0.0 | 1.0 | 0.0 |
| KGIDHJJC_47 | 0.0 | 1.0 | 0.0 |
| KGIDHJJC_48 | 0.0 | 1.0 | 0.0 |
PlasmidHunter v 1.4.5 (Database: May. 2024 release)
Prophage
Phigaro
| Query ID | Begin | End | Transposable | Taxonomy | pVOGs |
|---|---|---|---|---|---|
| No hit found | |||||
Phigaro v2.4.0 (Database: Jan. 2024 release)