Probiotic potential risk score
| ARGs | VFs | PGs | PPRS |
|---|---|---|---|
| 0 | 22 | 33 | 39.66 |
PPRS is classified as low-risk (≤4), medium-risk (4-6), and high-risk (≥6).
Antibiotic resistance genes
Comprehensive Antibiotic Resistance Database (CARD)
| Query ID | Begin | End | ARO name | ARO accession | CARD name | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
RGI v6.0.3 (Database: CARD Variants v4.0.2, Nov. 2023 release)
ResFinder
| Query ID | Begin | End | Resistance gene | Phenotype | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|
| No hit found | |||||||
ResFinder v4.6.0 (Database: resfinder_db, Aug. 2024 release)
AMRFinderPlus
| Query ID | Begin | End | Gene symbol | Sequence name | Method | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
AMRFinderPlus v4.0.3 (Database: Oct. 2024 release)
Virulence factors
Virulence Factor Database (VFDB)
| Query ID | qstart | qend | Gene name | e-value | VF name | VF category | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|---|
| JEGGKGOF_15 | 22104 | 22913 | STU_RS16245 | 0.0 | Capsule | Immune modulation | 100.00 | 100.00 | WP_002948020 |
| JEGGKGOF_2 | 52680 | 53273 | STR_RS05880 | 0.0 | Capsule | Immune modulation | 99.83 | 100.00 | WP_011226149 |
| JEGGKGOF_15 | 20019 | 21167 | STU_RS16255 | 0.0 | Capsule | Immune modulation | 99.74 | 100.00 | WP_041828290 |
| JEGGKGOF_15 | 24138 | 25193 | STU_RS16235 | 0.0 | Capsule | Immune modulation | 99.72 | 100.00 | WP_002948022 |
| JEGGKGOF_2 | 52680 | 53273 | STER_RS06030 | 0.0 | Capsule | Immune modulation | 99.66 | 100.00 | WP_011226149 |
| JEGGKGOF_2 | 52680 | 53273 | STU_RS15260 | 0.0 | Capsule | Immune modulation | 99.66 | 100.00 | WP_011226149 |
| JEGGKGOF_30 | 20695 | 21534 | cbpD | 0.0 | Autolysin | Exoenzyme | 99.64 | 100.00 | WP_011226733 |
| JEGGKGOF_15 | 21164 | 22120 | STU_RS16250 | 0.0 | Capsule | Immune modulation | 99.58 | 100.00 | WP_011226328 |
| JEGGKGOF_2 | 51811 | 52680 | rfbA | 0.0 | Capsule | Immune modulation | 99.42 | 100.00 | WP_011681286 |
| JEGGKGOF_15 | 22913 | 24118 | STU_RS16240 | 0.0 | Capsule | Immune modulation | 99.42 | 100.00 | WP_011226326 |
| JEGGKGOF_24 | 112 | 1770 | fbp54 | 0.0 | FBPs | Adherence | 99.40 | 100.00 | WP_011227179 |
| JEGGKGOF_15 | 25190 | 26972 | STU_RS16230 | 0.0 | Capsule | Immune modulation | 99.38 | 99.89 | WP_011226325 |
| JEGGKGOF_5 | 52081 | 52871 | cshA | 0.0 | Cell surface hydrophobicity proteins | Adherence | 98.74 | 100.00 | - |
| JEGGKGOF_2 | 17154 | 17915 | srtA | 0.0 | Sortase A | Exoenzyme | 98.69 | 100.00 | - |
| JEGGKGOF_27 | 12142 | 13596 | STU_RS14650 | 0.0 | Capsule | Immune modulation | 98.28 | 100.00 | WP_011226049 |
| JEGGKGOF_27 | 11410 | 12141 | STR_RS05260 | 0.0 | Capsule | Immune modulation | 98.22 | 100.00 | WP_011227248 |
| JEGGKGOF_60 | 2448 | 3863 | STER_RS05250 | 0.0 | Capsule | Immune modulation | 98.02 | 100.00 | WP_011681165 |
| JEGGKGOF_27 | 12142 | 13596 | STR_RS05265 | 0.0 | Capsule | Immune modulation | 97.87 | 100.00 | WP_041827043 |
| JEGGKGOF_27 | 11410 | 12141 | STU_RS14645 | 0.0 | Capsule | Immune modulation | 97.81 | 100.00 | WP_011226048 |
| JEGGKGOF_27 | 12142 | 13596 | STER_RS05320 | 0.0 | Capsule | Immune modulation | 97.40 | 99.79 | WP_011681177 |
| JEGGKGOF_27 | 9959 | 10699 | STER_RS05305 | 0.0 | Capsule | Immune modulation | 97.30 | 100.00 | WP_011681174 |
| JEGGKGOF_15 | 19065 | 19916 | rfbD | 0.0 | Capsule | Immune modulation | 96.83 | 100.00 | WP_014621820 |
| JEGGKGOF_27 | 9964 | 10699 | STR_RS05250 | 0.0 | Capsule | Immune modulation | 96.74 | 98.13 | WP_011227246 |
| JEGGKGOF_27 | 11410 | 12141 | STER_RS05315 | 0.0 | Capsule | Immune modulation | 96.72 | 100.00 | WP_011681176 |
| JEGGKGOF_27 | 9959 | 10699 | STU_RS14635 | 0.0 | Capsule | Immune modulation | 96.63 | 100.00 | WP_011226046 |
| JEGGKGOF_27 | 10709 | 11401 | STR_RS05255 | 0.0 | Capsule | Immune modulation | 95.81 | 100.00 | WP_011227247 |
| JEGGKGOF_27 | 10709 | 11401 | STU_RS14640 | 0.0 | Capsule | Immune modulation | 95.81 | 100.00 | WP_011226047 |
| JEGGKGOF_27 | 10709 | 11401 | STER_RS05310 | 0.0 | Capsule | Immune modulation | 89.75 | 100.00 | WP_011681175 |
| JEGGKGOF_1 | 17281 | 18584 | eno | 0.0 | Streptococcal enolase | Exoenzyme | 88.02 | 99.54 | WP_000022832 |
| JEGGKGOF_38 | 14288 | 15298 | plr/gapA | 0.0 | Streptococcal plasmin receptor/GAPDH | Adherence | 87.17 | 99.80 | WP_002986042 |
| JEGGKGOF_35 | 2266 | 3549 | tig/ropA | 0.0 | Trigger factor | Stress survival | 80.65 | 99.77 | WP_000107753 |
| JEGGKGOF_2 | 53702 | 54748 | rfbB | 0.0 | Capsule | Immune modulation | 80.61 | 100.00 | WP_009659423 |
BLASTN v2.16.0 (Database: VFDB, Dec. 2024 release)
VirulenceFinder
| Query ID | Begin | End | Database | Virulence factor | Protein function | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
VirulenceFinder v2.0. 4 (Database: virulencefinder_db, Feb . 2024 release)
Pathogenic genes
PHI-base
| Query ID | qstart | qend | Gene name | e-value | Function | Identity | Coverage | Gene ID |
|---|---|---|---|---|---|---|---|---|
| JEGGKGOF_2 | 14467 | 13484 | ldh(Sp_1220) | 0.0 | L-lactate dehydrogenase | 94.82 | 100.00 | AAK75326 |
| JEGGKGOF_22 | 9032 | 7959 | MntE | 0.0 | manganese homeostasis | 94.41 | 99.72 | ABF32167 |
| JEGGKGOF_3 | 17070 | 14767 | pfl2(Sp_0459) | 0.0 | formate acetyltransferase | 93.23 | 99.22 | AAK74619 |
| JEGGKGOF_10 | 33904 | 32936 | spr0084 | 0.0 | pathogenitcity related | 92.57 | 98.48 | AAK98888 |
| JEGGKGOF_36 | 5602 | 7848 | metE | 0.0 | methionine biosynthesis enzymes | 91.86 | 100.00 | AAK74738 |
| JEGGKGOF_7 | 48576 | 50057 | SPD_0310 | 0.0 | UPF0371 protein SPD_0310 | 91.70 | 100.00 | ABJ54480 |
| JEGGKGOF_30 | 1906 | 914 | recA | 0.0 | DNA recombination and repair | 91.24 | 85.31 | AAL00560 |
| JEGGKGOF_33 | 3269 | 4240 | prsA2 | 0.0 | ribose-phosphate pyrophosphokinase | 90.12 | 100.00 | ABF36968 |
| JEGGKGOF_20 | 23234 | 22083 | potA | 0.0 | ABC transporter ATP-binding protein-spermidine/putrescine transport | 89.06 | 99.74 | AAL00050 |
| JEGGKGOF_15 | 4145 | 6133 | uvrB | 0.0 | excinuclease ABC, B subunit | 88.99 | 100.00 | AE014259_2 |
| JEGGKGOF_2 | 30663 | 32393 | ptsI | 0.0 | phosphoenolpyruvate-protein phosphotransferase | 87.69 | 100.00 | AAK34199 |
| JEGGKGOF_25 | 26985 | 28463 | IMPDH | 0.0 | inosine-5'-monophosphate dehydrogenase | 87.42 | 100.00 | ADE32434 |
| JEGGKGOF_1 | 17281 | 18582 | Eno | 0.0 | enolase | 86.21 | 99.77 | ABP90468 |
| JEGGKGOF_9 | 13769 | 15661 | gidA | 0.0 | tRNA uridine 5-carboxymethylaminomethyl modification enzyme | 86.05 | 98.90 | ABP91129 |
| JEGGKGOF_36 | 10774 | 9065 | PGM | 0.0 | phosphoglucomutase | 83.71 | 99.65 | ACH87041 |
| JEGGKGOF_6 | 55109 | 54099 | pdh | 0.0 | pyruvate dehydrogenase | 83.09 | 99.70 | ABP91006 |
| JEGGKGOF_13 | 29839 | 31200 | mnmE | 0.0 | central tRNA-modifying GTPase | 82.02 | 99.56 | ABP90420 |
| JEGGKGOF_6 | 4797 | 6689 | PepO | 0.0 | endopeptidase | 80.03 | 100.00 | ABF32980 |
| JEGGKGOF_1 | 2837 | 3727 | bglB | 6.57e-180 | putative phospho--glucosidase | 88.89 | 99.66 | AAK33487 |
| JEGGKGOF_16 | 1475 | 537 | SP_0676 | 2.77e-169 | transcription facot | 81.15 | 97.20 | AAK74821 |
| JEGGKGOF_36 | 8040 | 8897 | metF | 7.65e-167 | methionine biosynthesis enzymes | 86.36 | 99.31 | AAK74739 |
| JEGGKGOF_5 | 24386 | 23682 | covR | 5.90e-131 | responder protein | 84.68 | 100.00 | AAK71319 |
| JEGGKGOF_7 | 16473 | 15802 | rr01 | 1.94e-125 | response regulator | 83.93 | 99.56 | CAB54566 |
| JEGGKGOF_36 | 14728 | 15396 | CiaR | 1.56e-122 | two-component response regulator | 85.65 | 99.55 | AAK74935 |
| JEGGKGOF_5 | 24386 | 23682 | walR | 2.56e-122 | DNA-binding response regulator | 81.28 | 100.00 | ANC99504 |
| JEGGKGOF_36 | 14728 | 15399 | ciaR | 1.87e-120 | two component system response regulator | 83.48 | 99.12 | AIK75708 |
| JEGGKGOF_28 | 6887 | 6201 | CovR | 1.22e-119 | serves to repress GAS virulence factor-encoding genes | 80.79 | 100.00 | ACE75886 |
| JEGGKGOF_30 | 617 | 222 | SpxA2 | 4.31e-76 | transcriptional regulator | 90.91 | 100.00 | ERL21461 |
| JEGGKGOF_13 | 18563 | 18162 | SpxA1 | 8.88e-68 | transcriptional regulator | 80.60 | 100.00 | ERL19273 |
| JEGGKGOF_18 | 13106 | 13393 | spr0479 | 3.12e-49 | essential gene | 86.46 | 98.97 | AAK99283 |
| JEGGKGOF_4 | 61988 | 62242 | spr1327 | 1.07e-45 | essential gene | 95.29 | 100.00 | AAL00131 |
| JEGGKGOF_9 | 47395 | 47132 | spr0175 | 2.84e-42 | pathogenitcity related | 84.09 | 100.00 | AAK98979 |
| JEGGKGOF_9 | 46592 | 46302 | spr0177 | 3.63e-37 | essential gene | 80.00 | 98.02 | AAK98981 |
| JEGGKGOF_35 | 3707 | 4207 | RopE (M5005_Spy_1611) | 4.46e-77 | probable DNA-directed RNA polymerase subunit delta | 81.44 | 87.43 | AAK34603 |
| JEGGKGOF_3 | 17070 | 14773 | PFL (B9H01_RS01125) | 0.0 | formate C-acetyltransferase | 83.07 | 98.08 | MYN69560 |
| JEGGKGOF_6 | 19259 | 20278 | ilvC (SPD_0406) | 0.0 | ketol-acid reductoisomerase (NADP(+)) | 96.47 | 100.00 | ABJ55451 |
BLASTX v2.16.0 (Database: PHI base v4.16, May. 2024 release)
Plasmid
PlasmidFinder
| Query ID | Begin | End | Plasmid | Query / Template | Identity | Accession no. |
|---|---|---|---|---|---|---|
| No hit found | ||||||
PlasmidFinder v 2.1.6 (Database: plasmidfinder_db v 2.2.0 , Nov. 2024 release)
PlasmidHunter
| Query ID | Prediction | Chromosome | Plasmid |
|---|---|---|---|
| JEGGKGOF_1 | 0.0 | 1.0 | 0.0 |
| JEGGKGOF_2 | 0.0 | 1.0 | 0.0 |
| JEGGKGOF_3 | 0.0 | 1.0 | 0.0 |
| JEGGKGOF_4 | 0.0 | 1.0 | 0.0 |
| JEGGKGOF_5 | 0.0 | 1.0 | 0.0 |
| JEGGKGOF_6 | 0.0 | 1.0 | 0.0 |
| JEGGKGOF_7 | 0.0 | 1.0 | 0.0 |
| JEGGKGOF_8 | 0.0 | 1.0 | 0.0 |
| JEGGKGOF_9 | 0.0 | 1.0 | 0.0 |
| JEGGKGOF_10 | 0.0 | 1.0 | 0.0 |
| JEGGKGOF_11 | 0.0 | 1.0 | 0.0 |
| JEGGKGOF_12 | 0.0 | 1.0 | 0.0 |
| JEGGKGOF_13 | 0.0 | 1.0 | 0.0 |
| JEGGKGOF_14 | 0.0 | 1.0 | 0.0 |
| JEGGKGOF_15 | 0.0 | 1.0 | 0.0 |
| JEGGKGOF_16 | 0.0 | 1.0 | 0.0 |
| JEGGKGOF_17 | 0.0 | 1.0 | 0.0 |
| JEGGKGOF_18 | 0.0 | 1.0 | 0.0 |
| JEGGKGOF_19 | 0.0 | 1.0 | 0.0 |
| JEGGKGOF_20 | 0.0 | 1.0 | 0.0 |
| JEGGKGOF_21 | 0.0 | 1.0 | 0.0 |
| JEGGKGOF_22 | 0.0 | 1.0 | 0.0 |
| JEGGKGOF_23 | 0.0 | 1.0 | 0.0 |
| JEGGKGOF_24 | 0.0 | 1.0 | 0.0 |
| JEGGKGOF_25 | 0.0 | 1.0 | 0.0 |
| JEGGKGOF_26 | 0.0 | 1.0 | 0.0 |
| JEGGKGOF_27 | 0.0 | 1.0 | 0.0 |
| JEGGKGOF_28 | 0.0 | 1.0 | 0.0 |
| JEGGKGOF_29 | 0.0 | 1.0 | 0.0 |
| JEGGKGOF_30 | 0.0 | 1.0 | 0.0 |
| JEGGKGOF_31 | 0.0 | 1.0 | 0.0 |
| JEGGKGOF_32 | 0.0 | 1.0 | 0.0 |
| JEGGKGOF_33 | 0.0 | 1.0 | 0.0 |
| JEGGKGOF_34 | 0.0 | 1.0 | 0.0 |
| JEGGKGOF_35 | 0.0 | 1.0 | 0.0 |
| JEGGKGOF_36 | 0.0 | 1.0 | 0.0 |
| JEGGKGOF_37 | 0.0 | 1.0 | 0.0 |
| JEGGKGOF_38 | 0.0 | 1.0 | 0.0 |
| JEGGKGOF_39 | 0.0 | 1.0 | 0.0 |
| JEGGKGOF_40 | 0.0 | 1.0 | 0.0 |
| JEGGKGOF_41 | 0.0 | 1.0 | 0.0 |
| JEGGKGOF_42 | 0.0 | 1.0 | 0.0 |
| JEGGKGOF_43 | 0.0 | 1.0 | 0.0 |
| JEGGKGOF_44 | 1.0 | 0.0 | 1.0 |
| JEGGKGOF_45 | 0.0 | 1.0 | 0.0 |
| JEGGKGOF_46 | 1.0 | 0.0 | 1.0 |
| JEGGKGOF_47 | 0.0 | 1.0 | 0.0 |
| JEGGKGOF_48 | 0.0 | 1.0 | 0.0 |
| JEGGKGOF_49 | 1.0 | 0.0 | 1.0 |
| JEGGKGOF_50 | 0.0 | 1.0 | 0.0 |
| JEGGKGOF_51 | 0.0 | 1.0 | 0.0 |
| JEGGKGOF_52 | 0.0 | 1.0 | 0.0 |
| JEGGKGOF_53 | 1.0 | 0.0 | 1.0 |
| JEGGKGOF_54 | 0.0 | 1.0 | 0.0 |
| JEGGKGOF_55 | 1.0 | 0.0 | 1.0 |
| JEGGKGOF_56 | 1.0 | 0.0 | 1.0 |
| JEGGKGOF_58 | 0.0 | 1.0 | 0.0 |
| JEGGKGOF_59 | 0.0 | 1.0 | 0.0 |
| JEGGKGOF_60 | 1.0 | 0.0 | 1.0 |
| JEGGKGOF_61 | 0.0 | 1.0 | 0.0 |
| JEGGKGOF_62 | 0.0 | 1.0 | 0.0 |
| JEGGKGOF_63 | 0.0 | 1.0 | 0.0 |
| JEGGKGOF_64 | 0.0 | 1.0 | 0.0 |
| JEGGKGOF_65 | 1.0 | 0.0 | 1.0 |
| JEGGKGOF_66 | 0.0 | 1.0 | 0.0 |
| JEGGKGOF_67 | 1.0 | 0.0 | 1.0 |
| JEGGKGOF_68 | 0.0 | 1.0 | 0.0 |
| JEGGKGOF_69 | 1.0 | 0.0 | 1.0 |
| JEGGKGOF_70 | 0.0 | 1.0 | 0.0 |
| JEGGKGOF_71 | 0.0 | 1.0 | 0.0 |
| JEGGKGOF_72 | 0.0 | 1.0 | 0.0 |
| JEGGKGOF_73 | 0.0 | 1.0 | 0.0 |
| JEGGKGOF_74 | 0.0 | 1.0 | 0.0 |
| JEGGKGOF_75 | 0.0 | 1.0 | 0.0 |
| JEGGKGOF_76 | 1.0 | 0.0 | 1.0 |
| JEGGKGOF_77 | 1.0 | 0.0 | 1.0 |
PlasmidHunter v 1.4.5 (Database: May. 2024 release)
Prophage
Phigaro
| Query ID | Begin | End | Transposable | Taxonomy | pVOGs |
|---|---|---|---|---|---|
| No hit found | |||||
Phigaro v2.4.0 (Database: Jan. 2024 release)