Probiotic potential risk score
| ARGs | VFs | PGs | PPRS |
|---|---|---|---|
| 10 | 10 | 9 | 16.76 |
PPRS is classified as low-risk (≤4), medium-risk (4-6), and high-risk (≥6).
Antibiotic resistance genes
Comprehensive Antibiotic Resistance Database (CARD)
| Query ID | Begin | End | ARO name | ARO accession | CARD name | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| OICBPDGN_48 | 84755 | 85093 | ykkC | ARO:3003063 | ykkC | 98.21 | 100.00 | AL009126.1 |
| OICBPDGN_48 | 84438 | 84755 | ykkD | ARO:3003064 | ykkD | 98.10 | 100.00 | AL009126.1 |
| OICBPDGN_3 | 59870 | 61516 | vmlR | ARO:3004476 | vmlR | 98.36 | 100.18 | NC_000964.3 |
| OICBPDGN_40 | 47999 | 49438 | lmrB | ARO:3002813 | lmrB | 99.58 | 100.42 | JYFL01000006.1 |
| OICBPDGN_40 | 35184 | 36104 | mphK | ARO:3004541 | mphK | 98.68 | 100.00 | CP010314.1 |
| OICBPDGN_16 | 27309 | 29879 | Bacillus subtilis mprF | ARO:3003324 | Bsub_mprF | 99.53 | 100.00 | AL009126.3 |
| OICBPDGN_12 | 23942 | 24796 | aadK | ARO:3002627 | aadK | 98.59 | 100.00 | AL009126.1 |
| OICBPDGN_15 | 19002 | 19595 | tmrB | ARO:3003059 | tmrB | 99.49 | 100.00 | AL009126.3 |
| OICBPDGN_12 | 6845 | 8047 | blt | ARO:3003006 | blt | 98.00 | 100.00 | L32599.1 |
RGI v6.0.3 (Database: CARD Variants v4.0.2, Nov. 2023 release)
ResFinder
| Query ID | Begin | End | Resistance gene | Phenotype | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|
| OICBPDGN_12 | 23942 | 24796 | aadK | Streptomycin | 98.83 | 100.00 | M26879 |
| OICBPDGN_40 | 35184 | 36104 | mph(K) | Spiramycin, Telithromycin | 98.05 | 100.00 | NC_000964 |
ResFinder v4.6.0 (Database: resfinder_db, Aug. 2024 release)
AMRFinderPlus
| Query ID | Begin | End | Gene symbol | Sequence name | Method | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| OICBPDGN_40 | 35184 | 36092 | mphK | macrolide 2'-phosphotransferase MphK | BLASTX | 98.68 | 99.02 | WP_003246254.1 |
| OICBPDGN_12 | 23945 | 24796 | aadK | aminoglycoside 6-adenylyltransferase AadK | BLASTX | 98.59 | 100.00 | WP_003229862.1 |
| OICBPDGN_3 | 59873 | 61516 | vmlR | ABC-F type ribosomal protection protein VmlR | BLASTX | 98.36 | 100.00 | WP_003234144.1 |
| OICBPDGN_9 | 40885 | 41403 | satA | streptothricin N-acetyltransferase SatA | BLASTX | 90.75 | 100.00 | WP_003242546.1 |
AMRFinderPlus v4.0.3 (Database: Oct. 2024 release)
Virulence factors
Virulence Factor Database (VFDB)
| Query ID | qstart | qend | Gene name | e-value | VF name | VF category | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|---|
| OICBPDGN_8 | 29572 | 30753 | capB | 0.0 | Capsule | Immune modulation | 99.66 | 100.00 | NP_391471 |
| OICBPDGN_26 | 35582 | 36367 | dhbA | 0.0 | Bacillibactin | Nutritional/Metabolic factor | 99.49 | 100.00 | NP_391080 |
| OICBPDGN_8 | 27947 | 29089 | capA | 0.0 | Capsule | Immune modulation | 99.30 | 100.00 | NP_391469 |
| OICBPDGN_26 | 24590 | 31726 | dhbF | 0.0 | Bacillibactin | Nutritional/Metabolic factor | 99.30 | 100.00 | NP_391076 |
| OICBPDGN_67 | 19800 | 21563 | dep/capD | 0.0 | Capsule | Immune modulation | 99.04 | 100.00 | NP_389723 |
| OICBPDGN_26 | 31746 | 32684 | dhbB | 0.0 | Bacillibactin | Nutritional/Metabolic factor | 99.04 | 100.00 | NP_391077 |
| OICBPDGN_26 | 34360 | 35556 | dhbC | 0.0 | Bacillibactin | Nutritional/Metabolic factor | 99.00 | 100.00 | NP_391079 |
| OICBPDGN_30 | 32646 | 33287 | hlyIII | 0.0 | Hemolysin III | Exotoxin | 98.91 | 100.00 | NP_390062 |
| OICBPDGN_8 | 29108 | 29557 | capC | 0.0 | Capsule | Immune modulation | 98.89 | 100.00 | NP_391470 |
| OICBPDGN_26 | 32712 | 34331 | dhbE | 0.0 | Bacillibactin | Nutritional/Metabolic factor | 96.73 | 100.00 | NP_391078 |
BLASTN v2.16.0 (Database: VFDB, Dec. 2024 release)
VirulenceFinder
| Query ID | Begin | End | Database | Virulence factor | Protein function | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
VirulenceFinder v2.0. 4 (Database: virulencefinder_db, Feb . 2024 release)
Pathogenic genes
PHI-base
| Query ID | qstart | qend | Gene name | e-value | Function | Identity | Coverage | Gene ID |
|---|---|---|---|---|---|---|---|---|
| OICBPDGN_6 | 31926 | 33062 | tufA | 0.0 | elongation factor Tu | 84.96 | 95.69 | AHM69299 |
| OICBPDGN_64 | 11359 | 10490 | pdxS | 1.95e-151 | encodes the putative pyridoxal 5'-phosphate synthase subunit PdxS | 83.45 | 98.31 | ACE61268 |
| OICBPDGN_7 | 116467 | 117243 | CodY | 1.70e-125 | nutrient-responsive regulator | 81.08 | 100.00 | ACJ80679 |
| OICBPDGN_24 | 4347 | 4916 | ClpP | 2.96e-100 | part of proteolytic complex | 81.05 | 97.44 | BAB94595 |
| OICBPDGN_83 | 3747 | 4139 | spxA1 | 2.93e-72 | redox-responsive transcription factor | 83.97 | 100.00 | AAF21893 |
| OICBPDGN_83 | 3747 | 4139 | spx | 1.75e-70 | essential gene which is a thiol/oxidative stress sensor | 80.15 | 100.00 | BAB57159 |
| OICBPDGN_29 | 20616 | 20858 | SpoVG | 7.51e-39 | RNA-binding protein | 81.48 | 79.41 | AAT02994 |
| OICBPDGN_3 | 13880 | 14077 | CspA | 3.90e-32 | cold shock protein | 90.91 | 100.00 | CAA62903 |
| OICBPDGN_30 | 44517 | 44711 | CspD | 4.65e-29 | cold shock protein | 81.54 | 98.48 | CAC99957 |
| OICBPDGN_74 | 32004 | 31810 | CspB | 3.77e-28 | cold shock protein | 83.08 | 98.48 | CAD00094 |
BLASTX v2.16.0 (Database: PHI base v4.16, May. 2024 release)
Plasmid
PlasmidFinder
| Query ID | Begin | End | Plasmid | Query / Template | Identity | Accession no. |
|---|---|---|---|---|---|---|
| OICBPDGN_14 | 4501 | 4668 | Col(SD853) | 168 / 194 | 86.90 | NC015392 |
PlasmidFinder v 2.1.6 (Database: plasmidfinder_db v 2.2.0 , Nov. 2024 release)
PlasmidHunter
| Query ID | Prediction | Chromosome | Plasmid |
|---|---|---|---|
| OICBPDGN_1 | 0.0 | 1.0 | 0.0 |
| OICBPDGN_2 | 0.0 | 1.0 | 0.0 |
| OICBPDGN_3 | 0.0 | 1.0 | 0.0 |
| OICBPDGN_4 | 0.0 | 1.0 | 0.0 |
| OICBPDGN_5 | 0.0 | 1.0 | 0.0 |
| OICBPDGN_6 | 0.0 | 1.0 | 0.0 |
| OICBPDGN_7 | 0.0 | 1.0 | 0.0 |
| OICBPDGN_8 | 0.0 | 1.0 | 0.0 |
| OICBPDGN_9 | 0.0 | 1.0 | 0.0 |
| OICBPDGN_10 | 0.0 | 1.0 | 0.0 |
| OICBPDGN_11 | 0.0 | 1.0 | 0.0 |
| OICBPDGN_12 | 0.0 | 1.0 | 0.0 |
| OICBPDGN_13 | 0.0 | 1.0 | 0.0 |
| OICBPDGN_14 | 1.0 | 0.0 | 1.0 |
| OICBPDGN_15 | 0.0 | 1.0 | 0.0 |
| OICBPDGN_16 | 0.0 | 1.0 | 0.0 |
| OICBPDGN_17 | 0.0 | 1.0 | 0.0 |
| OICBPDGN_18 | 0.0 | 1.0 | 0.0 |
| OICBPDGN_19 | 0.0 | 1.0 | 0.0 |
| OICBPDGN_20 | 0.0 | 1.0 | 0.0 |
| OICBPDGN_21 | 0.0 | 1.0 | 0.0 |
| OICBPDGN_22 | 0.0 | 1.0 | 0.0 |
| OICBPDGN_23 | 0.0 | 1.0 | 0.0 |
| OICBPDGN_24 | 0.0 | 1.0 | 0.0 |
| OICBPDGN_25 | 0.0 | 1.0 | 0.0 |
| OICBPDGN_26 | 0.0 | 1.0 | 0.0 |
| OICBPDGN_27 | 0.0 | 1.0 | 0.0 |
| OICBPDGN_28 | 0.0 | 1.0 | 0.0 |
| OICBPDGN_29 | 0.0 | 1.0 | 0.0 |
| OICBPDGN_30 | 0.0 | 1.0 | 0.0 |
| OICBPDGN_31 | 0.0 | 1.0 | 0.0 |
| OICBPDGN_32 | 0.0 | 1.0 | 0.0 |
| OICBPDGN_33 | 0.0 | 1.0 | 0.0 |
| OICBPDGN_34 | 0.0 | 1.0 | 0.0 |
| OICBPDGN_35 | 0.0 | 1.0 | 0.0 |
| OICBPDGN_36 | 0.0 | 1.0 | 0.0 |
| OICBPDGN_37 | 0.0 | 1.0 | 0.0 |
| OICBPDGN_38 | 0.0 | 1.0 | 0.0 |
| OICBPDGN_39 | 0.0 | 1.0 | 0.0 |
| OICBPDGN_40 | 0.0 | 1.0 | 0.0 |
| OICBPDGN_41 | 0.0 | 1.0 | 0.0 |
| OICBPDGN_42 | 0.0 | 1.0 | 0.0 |
| OICBPDGN_43 | 0.0 | 1.0 | 0.0 |
| OICBPDGN_44 | 0.0 | 1.0 | 0.0 |
| OICBPDGN_45 | 0.0 | 1.0 | 0.0 |
| OICBPDGN_46 | 1.0 | 0.0 | 1.0 |
| OICBPDGN_47 | 0.0 | 1.0 | 0.0 |
| OICBPDGN_48 | 0.0 | 1.0 | 0.0 |
| OICBPDGN_50 | 1.0 | 0.0 | 1.0 |
| OICBPDGN_51 | 0.0 | 1.0 | 0.0 |
| OICBPDGN_52 | 0.0 | 1.0 | 0.0 |
| OICBPDGN_53 | 0.0 | 1.0 | 0.0 |
| OICBPDGN_54 | 0.0 | 1.0 | 0.0 |
| OICBPDGN_55 | 0.0 | 1.0 | 0.0 |
| OICBPDGN_56 | 0.0 | 1.0 | 0.0 |
| OICBPDGN_57 | 0.0 | 1.0 | 0.0 |
| OICBPDGN_58 | 0.0 | 1.0 | 0.0 |
| OICBPDGN_59 | 0.0 | 1.0 | 0.0 |
| OICBPDGN_60 | 0.0 | 1.0 | 0.0 |
| OICBPDGN_61 | 0.0 | 1.0 | 0.0 |
| OICBPDGN_62 | 0.0 | 1.0 | 0.0 |
| OICBPDGN_63 | 1.0 | 0.0 | 1.0 |
| OICBPDGN_64 | 0.0 | 1.0 | 0.0 |
| OICBPDGN_65 | 0.0 | 1.0 | 0.0 |
| OICBPDGN_66 | 1.0 | 0.0 | 1.0 |
| OICBPDGN_67 | 0.0 | 1.0 | 0.0 |
| OICBPDGN_68 | 0.0 | 1.0 | 0.0 |
| OICBPDGN_69 | 0.0 | 1.0 | 0.0 |
| OICBPDGN_70 | 1.0 | 0.0 | 1.0 |
| OICBPDGN_71 | 1.0 | 0.0 | 1.0 |
| OICBPDGN_72 | 0.0 | 1.0 | 0.0 |
| OICBPDGN_74 | 0.0 | 1.0 | 0.0 |
| OICBPDGN_75 | 0.0 | 1.0 | 0.0 |
| OICBPDGN_76 | 0.0 | 1.0 | 0.0 |
| OICBPDGN_77 | 0.0 | 1.0 | 0.0 |
| OICBPDGN_78 | 0.0 | 1.0 | 0.0 |
| OICBPDGN_79 | 0.0 | 1.0 | 0.0 |
| OICBPDGN_80 | 1.0 | 0.0 | 1.0 |
| OICBPDGN_81 | 0.0 | 1.0 | 0.0 |
| OICBPDGN_82 | 0.0 | 1.0 | 0.0 |
| OICBPDGN_83 | 0.0 | 1.0 | 0.0 |
| OICBPDGN_84 | 0.0 | 1.0 | 0.0 |
| OICBPDGN_85 | 1.0 | 0.0 | 1.0 |
| OICBPDGN_86 | 0.0 | 1.0 | 0.0 |
| OICBPDGN_87 | 1.0 | 0.0 | 1.0 |
| OICBPDGN_88 | 0.0 | 1.0 | 0.0 |
| OICBPDGN_89 | 1.0 | 0.0 | 1.0 |
| OICBPDGN_90 | 0.0 | 1.0 | 0.0 |
| OICBPDGN_91 | 0.0 | 1.0 | 0.0 |
| OICBPDGN_93 | 1.0 | 0.0 | 1.0 |
| OICBPDGN_95 | 0.0 | 1.0 | 0.0 |
| OICBPDGN_96 | 1.0 | 0.0 | 1.0 |
| OICBPDGN_97 | 1.0 | 0.0 | 1.0 |
| OICBPDGN_98 | 1.0 | 0.0 | 1.0 |
| OICBPDGN_99 | 0.0 | 1.0 | 0.0 |
PlasmidHunter v 1.4.5 (Database: May. 2024 release)
Prophage
Phigaro
| Query ID | Begin | End | Transposable | Taxonomy | pVOGs |
|---|---|---|---|---|---|
| OICBPDGN_44 | 4946 | 15476 | True | Siphoviridae | VOG6587, VOG0189, VOG4566, VOG7581, VOG9667, VOG9667, VOG1563, VOG0275, VOG0275 |
| OICBPDGN_48 | 114557 | 141240 | False | Myoviridae | VOG0753, VOG4705, VOG7718, VOG4862, VOG4691, VOG4550, VOG3894, VOG4885, VOG4865, VOG6163, VOG3892, VOG3891, VOG3890, VOG0749, VOG4685, VOG4773, VOG10227, VOG0796, VOG5447, VOG4843, VOG0189, VOG3490 |
Phigaro v2.4.0 (Database: Jan. 2024 release)