Probiotic potential risk score
| ARGs | VFs | PGs | PPRS |
|---|---|---|---|
| 0 | 23 | 33 | 40.22 |
PPRS is classified as low-risk (≤4), medium-risk (4-6), and high-risk (≥6).
Antibiotic resistance genes
Comprehensive Antibiotic Resistance Database (CARD)
| Query ID | Begin | End | ARO name | ARO accession | CARD name | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
RGI v6.0.3 (Database: CARD Variants v4.0.2, Nov. 2023 release)
ResFinder
| Query ID | Begin | End | Resistance gene | Phenotype | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|
| No hit found | |||||||
ResFinder v4.6.0 (Database: resfinder_db, Aug. 2024 release)
AMRFinderPlus
| Query ID | Begin | End | Gene symbol | Sequence name | Method | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
AMRFinderPlus v4.0.3 (Database: Oct. 2024 release)
Virulence factors
Virulence Factor Database (VFDB)
| Query ID | qstart | qend | Gene name | e-value | VF name | VF category | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|---|
| OKDPILCH_11 | 9492 | 10361 | rfbA | 0.0 | Capsule | Immune modulation | 100.00 | 100.00 | WP_011681286 |
| OKDPILCH_11 | 8899 | 9492 | STER_RS06030 | 0.0 | Capsule | Immune modulation | 100.00 | 100.00 | WP_011226149 |
| OKDPILCH_5 | 33598 | 34407 | STU_RS16245 | 0.0 | Capsule | Immune modulation | 99.88 | 100.00 | WP_002948020 |
| OKDPILCH_4 | 109307 | 110767 | STER_RS05320 | 0.0 | Capsule | Immune modulation | 99.86 | 100.00 | WP_011681177 |
| OKDPILCH_11 | 8899 | 9492 | STR_RS05880 | 0.0 | Capsule | Immune modulation | 99.83 | 100.00 | WP_011226149 |
| OKDPILCH_5 | 32658 | 33614 | STU_RS16250 | 0.0 | Capsule | Immune modulation | 99.79 | 100.00 | WP_011226328 |
| OKDPILCH_5 | 31513 | 32661 | STU_RS16255 | 0.0 | Capsule | Immune modulation | 99.74 | 100.00 | WP_041828290 |
| OKDPILCH_11 | 8899 | 9492 | STU_RS15260 | 0.0 | Capsule | Immune modulation | 99.66 | 100.00 | WP_011226149 |
| OKDPILCH_1 | 219331 | 220474 | cshA | 0.0 | Cell surface hydrophobicity proteins | Adherence | 99.65 | 100.00 | - |
| OKDPILCH_3 | 13365 | 15023 | fbp54 | 0.0 | FBPs | Adherence | 99.64 | 100.00 | WP_011227179 |
| OKDPILCH_14 | 20658 | 21497 | cbpD | 0.0 | Autolysin | Exoenzyme | 99.52 | 100.00 | WP_011226733 |
| OKDPILCH_5 | 36684 | 38468 | STU_RS16230 | 0.0 | Capsule | Immune modulation | 99.50 | 100.00 | WP_011226325 |
| OKDPILCH_5 | 34407 | 35612 | STU_RS16240 | 0.0 | Capsule | Immune modulation | 99.50 | 100.00 | WP_011226326 |
| OKDPILCH_5 | 35632 | 36687 | STU_RS16235 | 0.0 | Capsule | Immune modulation | 99.43 | 100.00 | WP_002948022 |
| OKDPILCH_4 | 110768 | 111499 | STER_RS05315 | 0.0 | Capsule | Immune modulation | 99.32 | 100.00 | WP_011681176 |
| OKDPILCH_4 | 112210 | 112950 | STER_RS05305 | 0.0 | Capsule | Immune modulation | 98.52 | 100.00 | WP_011681174 |
| OKDPILCH_4 | 112210 | 112950 | STU_RS14635 | 0.0 | Capsule | Immune modulation | 98.38 | 100.00 | WP_011226046 |
| OKDPILCH_4 | 110768 | 111499 | STR_RS05260 | 0.0 | Capsule | Immune modulation | 98.36 | 100.00 | WP_011227248 |
| OKDPILCH_4 | 110768 | 111499 | STU_RS14645 | 0.0 | Capsule | Immune modulation | 98.22 | 100.00 | WP_011226048 |
| OKDPILCH_11 | 44262 | 45023 | srtA | 0.0 | Sortase A | Exoenzyme | 98.03 | 100.00 | - |
| OKDPILCH_4 | 112210 | 112945 | STR_RS05250 | 0.0 | Capsule | Immune modulation | 97.83 | 98.13 | WP_011227246 |
| OKDPILCH_4 | 109307 | 110767 | STU_RS14650 | 0.0 | Capsule | Immune modulation | 97.33 | 100.21 | WP_011226049 |
| OKDPILCH_4 | 111508 | 112200 | STU_RS14640 | 0.0 | Capsule | Immune modulation | 96.83 | 100.00 | WP_011226047 |
| OKDPILCH_4 | 109307 | 110767 | STR_RS05265 | 0.0 | Capsule | Immune modulation | 96.78 | 100.21 | WP_041827043 |
| OKDPILCH_5 | 27160 | 28011 | rfbD | 0.0 | Capsule | Immune modulation | 96.60 | 100.00 | WP_014621820 |
| OKDPILCH_4 | 113007 | 114374 | STU_RS14630 | 0.0 | Capsule | Immune modulation | 96.27 | 100.00 | WP_011226045 |
| OKDPILCH_4 | 111508 | 112200 | STR_RS05255 | 0.0 | Capsule | Immune modulation | 96.25 | 100.00 | WP_011227247 |
| OKDPILCH_4 | 113007 | 114372 | STER_RS05300 | 0.0 | Capsule | Immune modulation | 95.09 | 99.85 | WP_011681173 |
| OKDPILCH_4 | 111508 | 112200 | STER_RS05310 | 0.0 | Capsule | Immune modulation | 92.78 | 100.00 | WP_011681175 |
| OKDPILCH_5 | 29114 | 30388 | STU_RS16265 | 0.0 | Capsule | Immune modulation | 91.06 | 100.00 | WP_011226331 |
| OKDPILCH_1 | 117700 | 119003 | eno | 0.0 | Streptococcal enolase | Exoenzyme | 88.10 | 99.46 | WP_000022832 |
| OKDPILCH_24 | 14220 | 15230 | plr/gapA | 0.0 | Streptococcal plasmin receptor/GAPDH | Adherence | 87.56 | 99.80 | WP_002986042 |
| OKDPILCH_12 | 57245 | 58528 | tig/ropA | 0.0 | Trigger factor | Stress survival | 80.73 | 99.77 | WP_000107753 |
| OKDPILCH_11 | 7424 | 8470 | rfbB | 0.0 | Capsule | Immune modulation | 80.61 | 100.00 | WP_009659423 |
BLASTN v2.16.0 (Database: VFDB, Dec. 2024 release)
VirulenceFinder
| Query ID | Begin | End | Database | Virulence factor | Protein function | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
VirulenceFinder v2.0. 4 (Database: virulencefinder_db, Feb . 2024 release)
Pathogenic genes
PHI-base
| Query ID | qstart | qend | Gene name | e-value | Function | Identity | Coverage | Gene ID |
|---|---|---|---|---|---|---|---|---|
| OKDPILCH_11 | 47710 | 48693 | ldh(Sp_1220) | 0.0 | L-lactate dehydrogenase | 94.82 | 100.00 | AAK75326 |
| OKDPILCH_1 | 13921 | 12848 | MntE | 0.0 | manganese homeostasis | 94.41 | 99.72 | ABF32167 |
| OKDPILCH_2 | 46051 | 43748 | pfl2(Sp_0459) | 0.0 | formate acetyltransferase | 92.97 | 99.22 | AAK74619 |
| OKDPILCH_1 | 201237 | 200269 | spr0084 | 0.0 | pathogenitcity related | 92.88 | 98.48 | AAK98888 |
| OKDPILCH_8 | 69093 | 70574 | SPD_0310 | 0.0 | UPF0371 protein SPD_0310 | 92.11 | 100.00 | ABJ54480 |
| OKDPILCH_23 | 5485 | 7731 | metE | 0.0 | methionine biosynthesis enzymes | 91.99 | 100.00 | AAK74738 |
| OKDPILCH_14 | 1866 | 868 | recA | 0.0 | DNA recombination and repair | 91.29 | 85.82 | AAL00560 |
| OKDPILCH_14 | 37981 | 37010 | prsA2 | 0.0 | ribose-phosphate pyrophosphokinase | 90.12 | 100.00 | ABF36968 |
| OKDPILCH_2 | 167448 | 168599 | potA | 0.0 | ABC transporter ATP-binding protein-spermidine/putrescine transport | 89.32 | 99.74 | AAL00050 |
| OKDPILCH_5 | 12190 | 14178 | uvrB | 0.0 | excinuclease ABC, B subunit | 88.99 | 100.00 | AE014259_2 |
| OKDPILCH_11 | 31511 | 29781 | ptsI | 0.0 | phosphoenolpyruvate-protein phosphotransferase | 87.69 | 100.00 | AAK34199 |
| OKDPILCH_9 | 63932 | 62454 | IMPDH | 0.0 | inosine-5'-monophosphate dehydrogenase | 87.63 | 100.00 | ADE32434 |
| OKDPILCH_1 | 119003 | 117702 | Eno | 0.0 | enolase | 86.21 | 99.77 | ABP90468 |
| OKDPILCH_9 | 49199 | 47307 | gidA | 0.0 | tRNA uridine 5-carboxymethylaminomethyl modification enzyme | 85.74 | 98.90 | ABP91129 |
| OKDPILCH_23 | 10656 | 8947 | PGM | 0.0 | phosphoglucomutase | 84.06 | 99.65 | ACH87041 |
| OKDPILCH_10 | 54712 | 53702 | pdh | 0.0 | pyruvate dehydrogenase | 83.09 | 99.70 | ABP91006 |
| OKDPILCH_3 | 41286 | 39925 | mnmE | 0.0 | central tRNA-modifying GTPase | 82.24 | 99.56 | ABP90420 |
| OKDPILCH_10 | 4398 | 6290 | PepO | 0.0 | endopeptidase | 80.19 | 100.00 | ABF32980 |
| OKDPILCH_1 | 133438 | 132548 | bglB | 6.26e-179 | putative phospho--glucosidase | 88.55 | 99.66 | AAK33487 |
| OKDPILCH_3 | 147147 | 148085 | SP_0676 | 2.01e-168 | transcription facot | 81.15 | 97.20 | AAK74821 |
| OKDPILCH_23 | 7923 | 8780 | metF | 1.33e-166 | methionine biosynthesis enzymes | 86.36 | 99.31 | AAK74739 |
| OKDPILCH_4 | 72517 | 73221 | covR | 3.02e-132 | responder protein | 85.53 | 100.00 | AAK71319 |
| OKDPILCH_8 | 31230 | 30559 | rr01 | 1.33e-125 | response regulator | 83.93 | 99.56 | CAB54566 |
| OKDPILCH_4 | 72517 | 73221 | walR | 1.27e-122 | DNA-binding response regulator | 82.13 | 100.00 | ANC99504 |
| OKDPILCH_23 | 14610 | 15278 | CiaR | 4.51e-122 | two-component response regulator | 85.20 | 99.55 | AAK74935 |
| OKDPILCH_23 | 14610 | 15281 | ciaR | 6.59e-120 | two component system response regulator | 83.04 | 99.12 | AIK75708 |
| OKDPILCH_6 | 94486 | 95172 | CovR | 5.54e-119 | serves to repress GAS virulence factor-encoding genes | 80.79 | 100.00 | ACE75886 |
| OKDPILCH_14 | 592 | 218 | SpxA2 | 2.55e-71 | transcriptional regulator | 91.20 | 94.70 | ERL21461 |
| OKDPILCH_3 | 52751 | 53152 | SpxA1 | 3.22e-67 | transcriptional regulator | 80.60 | 100.00 | ERL19273 |
| OKDPILCH_15 | 13755 | 14042 | spr0479 | 2.99e-49 | essential gene | 86.46 | 98.97 | AAK99283 |
| OKDPILCH_16 | 10726 | 10980 | spr1327 | 4.97e-46 | essential gene | 95.29 | 100.00 | AAL00131 |
| OKDPILCH_9 | 15578 | 15841 | spr0175 | 2.99e-42 | pathogenitcity related | 84.09 | 100.00 | AAK98979 |
| OKDPILCH_9 | 16405 | 16671 | spr0177 | 6.54e-34 | essential gene | 84.27 | 88.12 | AAK98981 |
| OKDPILCH_12 | 57087 | 56587 | RopE (M5005_Spy_1611) | 1.68e-76 | probable DNA-directed RNA polymerase subunit delta | 81.44 | 87.43 | AAK34603 |
| OKDPILCH_2 | 46051 | 43754 | PFL (B9H01_RS01125) | 0.0 | formate C-acetyltransferase | 82.94 | 98.08 | MYN69560 |
| OKDPILCH_10 | 18855 | 19874 | ilvC (SPD_0406) | 0.0 | ketol-acid reductoisomerase (NADP(+)) | 96.47 | 100.00 | ABJ55451 |
BLASTX v2.16.0 (Database: PHI base v4.16, May. 2024 release)
Plasmid
PlasmidFinder
| Query ID | Begin | End | Plasmid | Query / Template | Identity | Accession no. |
|---|---|---|---|---|---|---|
| No hit found | ||||||
PlasmidFinder v 2.1.6 (Database: plasmidfinder_db v 2.2.0 , Nov. 2024 release)
PlasmidHunter
| Query ID | Prediction | Chromosome | Plasmid |
|---|---|---|---|
| OKDPILCH_1 | 0.0 | 1.0 | 0.0 |
| OKDPILCH_2 | 0.0 | 1.0 | 0.0 |
| OKDPILCH_3 | 0.0 | 1.0 | 0.0 |
| OKDPILCH_4 | 0.0 | 1.0 | 0.0 |
| OKDPILCH_5 | 0.0 | 1.0 | 0.0 |
| OKDPILCH_6 | 0.0 | 1.0 | 0.0 |
| OKDPILCH_7 | 0.0 | 1.0 | 0.0 |
| OKDPILCH_8 | 0.0 | 1.0 | 0.0 |
| OKDPILCH_9 | 0.0 | 1.0 | 0.0 |
| OKDPILCH_10 | 0.0 | 1.0 | 0.0 |
| OKDPILCH_11 | 0.0 | 1.0 | 0.0 |
| OKDPILCH_12 | 0.0 | 1.0 | 0.0 |
| OKDPILCH_13 | 0.0 | 1.0 | 0.0 |
| OKDPILCH_14 | 0.0 | 1.0 | 0.0 |
| OKDPILCH_15 | 0.0 | 1.0 | 0.0 |
| OKDPILCH_16 | 0.0 | 1.0 | 0.0 |
| OKDPILCH_17 | 0.0 | 1.0 | 0.0 |
| OKDPILCH_18 | 0.0 | 1.0 | 0.0 |
| OKDPILCH_19 | 0.0 | 1.0 | 0.0 |
| OKDPILCH_20 | 0.0 | 1.0 | 0.0 |
| OKDPILCH_21 | 0.0 | 1.0 | 0.0 |
| OKDPILCH_22 | 0.0 | 1.0 | 0.0 |
| OKDPILCH_23 | 0.0 | 1.0 | 0.0 |
| OKDPILCH_24 | 0.0 | 1.0 | 0.0 |
| OKDPILCH_25 | 0.0 | 1.0 | 0.0 |
| OKDPILCH_26 | 0.0 | 1.0 | 0.0 |
| OKDPILCH_27 | 0.0 | 1.0 | 0.0 |
| OKDPILCH_28 | 1.0 | 0.0 | 1.0 |
| OKDPILCH_29 | 0.0 | 1.0 | 0.0 |
| OKDPILCH_31 | 1.0 | 0.0 | 1.0 |
| OKDPILCH_32 | 0.0 | 1.0 | 0.0 |
| OKDPILCH_33 | 1.0 | 0.0 | 1.0 |
| OKDPILCH_34 | 1.0 | 0.0 | 1.0 |
| OKDPILCH_35 | 0.0 | 1.0 | 0.0 |
| OKDPILCH_36 | 1.0 | 0.0 | 1.0 |
| OKDPILCH_37 | 0.0 | 1.0 | 0.0 |
| OKDPILCH_38 | 0.0 | 1.0 | 0.0 |
| OKDPILCH_39 | 1.0 | 0.0 | 1.0 |
| OKDPILCH_40 | 0.0 | 1.0 | 0.0 |
| OKDPILCH_41 | 0.0 | 1.0 | 0.0 |
PlasmidHunter v 1.4.5 (Database: May. 2024 release)
Prophage
Phigaro
| Query ID | Begin | End | Transposable | Taxonomy | pVOGs |
|---|---|---|---|---|---|
| No hit found | |||||
Phigaro v2.4.0 (Database: Jan. 2024 release)