Probiotic potential risk score
| ARGs | VFs | PGs | PPRS |
|---|---|---|---|
| 0 | 23 | 30 | 37.80 |
PPRS is classified as low-risk (≤4), medium-risk (4-6), and high-risk (≥6).
Antibiotic resistance genes
Comprehensive Antibiotic Resistance Database (CARD)
| Query ID | Begin | End | ARO name | ARO accession | CARD name | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
RGI v6.0.3 (Database: CARD Variants v4.0.2, Nov. 2023 release)
ResFinder
| Query ID | Begin | End | Resistance gene | Phenotype | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|
| No hit found | |||||||
ResFinder v4.6.0 (Database: resfinder_db, Aug. 2024 release)
AMRFinderPlus
| Query ID | Begin | End | Gene symbol | Sequence name | Method | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
AMRFinderPlus v4.0.3 (Database: Oct. 2024 release)
Virulence factors
Virulence Factor Database (VFDB)
| Query ID | qstart | qend | Gene name | e-value | VF name | VF category | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|---|
| ONEGGOAA_1 | 43689 | 44528 | cbpD | 0.0 | Autolysin | Exoenzyme | 99.76 | 100.00 | WP_011226733 |
| ONEGGOAA_1 | 1381065 | 1382324 | STER_RS07100 | 0.0 | Capsule | Immune modulation | 99.76 | 100.00 | WP_011681445 |
| ONEGGOAA_1 | 897842 | 899500 | fbp54 | 0.0 | FBPs | Adherence | 99.52 | 100.00 | WP_011227179 |
| ONEGGOAA_1 | 1158656 | 1159249 | STR_RS05880 | 0.0 | Capsule | Immune modulation | 99.50 | 100.00 | WP_011226149 |
| ONEGGOAA_1 | 1380092 | 1381068 | STER_RS07095 | 0.0 | Capsule | Immune modulation | 99.39 | 99.90 | WP_011681444 |
| ONEGGOAA_1 | 1379106 | 1380074 | STER_RS07090 | 0.0 | Capsule | Immune modulation | 99.38 | 100.00 | WP_011681443 |
| ONEGGOAA_1 | 1158656 | 1159249 | STER_RS06030 | 0.0 | Capsule | Immune modulation | 99.33 | 100.00 | WP_011226149 |
| ONEGGOAA_1 | 1158656 | 1159249 | STU_RS15260 | 0.0 | Capsule | Immune modulation | 99.33 | 100.00 | WP_011226149 |
| ONEGGOAA_1 | 1159249 | 1160118 | rfbA | 0.0 | Capsule | Immune modulation | 99.19 | 100.00 | WP_011681286 |
| ONEGGOAA_1 | 1047238 | 1047969 | STU_RS14645 | 0.0 | Capsule | Immune modulation | 98.77 | 100.00 | WP_011226048 |
| ONEGGOAA_1 | 1113832 | 1114622 | cshA | 0.0 | Cell surface hydrophobicity proteins | Adherence | 98.74 | 99.87 | - |
| ONEGGOAA_1 | 1047238 | 1047969 | STER_RS05315 | 0.0 | Capsule | Immune modulation | 98.63 | 100.00 | WP_011681176 |
| ONEGGOAA_1 | 1194018 | 1194779 | srtA | 0.0 | Sortase A | Exoenzyme | 98.56 | 100.00 | - |
| ONEGGOAA_1 | 1047238 | 1047969 | STR_RS05260 | 0.0 | Capsule | Immune modulation | 98.50 | 100.00 | WP_011227248 |
| ONEGGOAA_1 | 1378389 | 1379104 | STER_RS07085 | 0.0 | Capsule | Immune modulation | 98.05 | 99.86 | WP_011681442 |
| ONEGGOAA_1 | 1045787 | 1046527 | STER_RS05305 | 0.0 | Capsule | Immune modulation | 97.98 | 100.00 | WP_011681174 |
| ONEGGOAA_1 | 1377267 | 1378043 | STER_RS07075 | 0.0 | Capsule | Immune modulation | 97.68 | 100.00 | WP_011681440 |
| ONEGGOAA_1 | 1047970 | 1049430 | STER_RS05320 | 0.0 | Capsule | Immune modulation | 97.60 | 100.00 | WP_011681177 |
| ONEGGOAA_1 | 1045787 | 1046527 | STU_RS14635 | 0.0 | Capsule | Immune modulation | 97.30 | 100.00 | WP_011226046 |
| ONEGGOAA_1 | 1045792 | 1046527 | STR_RS05250 | 0.0 | Capsule | Immune modulation | 97.01 | 98.13 | WP_011227246 |
| ONEGGOAA_1 | 1047970 | 1049430 | STU_RS14650 | 0.0 | Capsule | Immune modulation | 96.58 | 100.21 | WP_011226049 |
| ONEGGOAA_1 | 1382443 | 1383294 | rfbD | 0.0 | Capsule | Immune modulation | 96.24 | 100.00 | WP_014621820 |
| ONEGGOAA_1 | 622940 | 627835 | SAG_RS09105 | 0.0 | Agglutinin receptor | Adherence | 95.98 | 99.98 | WP_000167699 |
| ONEGGOAA_1 | 1047970 | 1049430 | STR_RS05265 | 0.0 | Capsule | Immune modulation | 95.96 | 100.21 | WP_041827043 |
| ONEGGOAA_1 | 622892 | 627835 | SSU98_0978 | 0.0 | Agglutinin receptor | Adherence | 95.65 | 99.78 | YP_001200536 |
| ONEGGOAA_1 | 622892 | 627835 | SSU05_0965 | 0.0 | Agglutinin receptor | Adherence | 95.63 | 99.78 | YP_001198331 |
| ONEGGOAA_1 | 1044364 | 1045729 | STER_RS05300 | 0.0 | Capsule | Immune modulation | 95.24 | 99.85 | WP_011681173 |
| ONEGGOAA_1 | 1044362 | 1045729 | STU_RS14630 | 0.0 | Capsule | Immune modulation | 95.17 | 100.00 | WP_011226045 |
| ONEGGOAA_1 | 1046537 | 1047229 | STER_RS05310 | 0.0 | Capsule | Immune modulation | 90.19 | 100.00 | WP_011681175 |
| ONEGGOAA_1 | 1046537 | 1047229 | STR_RS05255 | 0.0 | Capsule | Immune modulation | 89.61 | 100.00 | WP_011227247 |
| ONEGGOAA_1 | 1046537 | 1047229 | STU_RS14640 | 0.0 | Capsule | Immune modulation | 89.61 | 100.00 | WP_011226047 |
| ONEGGOAA_1 | 588194 | 589497 | eno | 0.0 | Streptococcal enolase | Exoenzyme | 88.24 | 99.54 | WP_000022832 |
| ONEGGOAA_1 | 1668664 | 1669674 | plr/gapA | 0.0 | Streptococcal plasmin receptor/GAPDH | Adherence | 86.92 | 99.51 | WP_002986042 |
| ONEGGOAA_1 | 148937 | 150220 | tig/ropA | 0.0 | Trigger factor | Stress survival | 80.58 | 99.77 | WP_000107753 |
| ONEGGOAA_1 | 1157180 | 1158226 | rfbB | 0.0 | Capsule | Immune modulation | 80.42 | 100.00 | WP_009659423 |
| ONEGGOAA_1 | 1034691 | 1035274 | SPD_RS01775 | 5.14e-145 | Capsule | Immune modulation | 82.91 | 96.20 | WP_001819836 |
BLASTN v2.16.0 (Database: VFDB, Dec. 2024 release)
VirulenceFinder
| Query ID | Begin | End | Database | Virulence factor | Protein function | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
VirulenceFinder v2.0. 4 (Database: virulencefinder_db, Feb . 2024 release)
Pathogenic genes
PHI-base
| Query ID | qstart | qend | Gene name | e-value | Function | Identity | Coverage | Gene ID |
|---|---|---|---|---|---|---|---|---|
| ONEGGOAA_1 | 622919 | 627832 | B9H01_RS04765 | 0.0 | glucan-binding protein | 97.07 | 99.70 | AUS90958 |
| ONEGGOAA_1 | 1197466 | 1198449 | ldh(Sp_1220) | 0.0 | L-lactate dehydrogenase | 94.82 | 100.00 | AAK75326 |
| ONEGGOAA_1 | 745173 | 746246 | MntE | 0.0 | manganese homeostasis | 94.41 | 99.72 | ABF32167 |
| ONEGGOAA_1 | 505992 | 506960 | spr0084 | 0.0 | pathogenitcity related | 93.19 | 98.48 | AAK98888 |
| ONEGGOAA_1 | 1546014 | 1548317 | pfl2(Sp_0459) | 0.0 | formate acetyltransferase | 93.10 | 99.22 | AAK74619 |
| ONEGGOAA_1 | 773889 | 776135 | metE | 0.0 | methionine biosynthesis enzymes | 91.99 | 100.00 | AAK74738 |
| ONEGGOAA_1 | 1277481 | 1278962 | SPD_0310 | 0.0 | UPF0371 protein SPD_0310 | 91.90 | 100.00 | ABJ54480 |
| ONEGGOAA_1 | 65609 | 66601 | recA | 0.0 | DNA recombination and repair | 91.24 | 85.31 | AAL00560 |
| ONEGGOAA_1 | 27208 | 28179 | prsA2 | 0.0 | ribose-phosphate pyrophosphokinase | 90.12 | 100.00 | ABF36968 |
| ONEGGOAA_1 | 1432177 | 1431026 | potA | 0.0 | ABC transporter ATP-binding protein-spermidine/putrescine transport | 89.06 | 99.74 | AAL00050 |
| ONEGGOAA_1 | 1396544 | 1394556 | uvrB | 0.0 | excinuclease ABC, B subunit | 88.99 | 100.00 | AE014259_2 |
| ONEGGOAA_1 | 1181269 | 1179539 | ptsI | 0.0 | phosphoenolpyruvate-protein phosphotransferase | 87.87 | 100.00 | AAK34199 |
| ONEGGOAA_1 | 1861060 | 1859582 | IMPDH | 0.0 | inosine-5'-monophosphate dehydrogenase | 87.42 | 100.00 | ADE32434 |
| ONEGGOAA_1 | 588194 | 589495 | Eno | 0.0 | enolase | 86.21 | 99.77 | ABP90468 |
| ONEGGOAA_1 | 1846293 | 1844401 | gidA | 0.0 | tRNA uridine 5-carboxymethylaminomethyl modification enzyme | 85.89 | 98.90 | ABP91129 |
| ONEGGOAA_1 | 779060 | 777351 | PGM | 0.0 | phosphoglucomutase | 83.54 | 99.65 | ACH87041 |
| ONEGGOAA_1 | 1713037 | 1714047 | pdh | 0.0 | pyruvate dehydrogenase | 83.09 | 99.70 | ABP91006 |
| ONEGGOAA_1 | 926262 | 924901 | mnmE | 0.0 | central tRNA-modifying GTPase | 82.24 | 99.56 | ABP90420 |
| ONEGGOAA_1 | 1763303 | 1761411 | PepO | 0.0 | endopeptidase | 80.19 | 100.00 | ABF32980 |
| ONEGGOAA_1 | 573763 | 574653 | bglB | 1.34e-178 | putative phospho--glucosidase | 88.89 | 99.66 | AAK33487 |
| ONEGGOAA_1 | 838609 | 837671 | SP_0676 | 8.30e-168 | transcription facot | 81.47 | 97.20 | AAK74821 |
| ONEGGOAA_1 | 776327 | 777184 | metF | 8.73e-165 | methionine biosynthesis enzymes | 86.36 | 99.31 | AAK74739 |
| ONEGGOAA_1 | 1086261 | 1085557 | covR | 1.08e-130 | responder protein | 85.11 | 100.00 | AAK71319 |
| ONEGGOAA_1 | 1249874 | 1249203 | rr01 | 2.98e-125 | response regulator | 84.38 | 99.56 | CAB54566 |
| ONEGGOAA_1 | 1086261 | 1085557 | walR | 5.40e-121 | DNA-binding response regulator | 81.28 | 100.00 | ANC99504 |
| ONEGGOAA_1 | 783014 | 783682 | CiaR | 6.16e-121 | two-component response regulator | 86.10 | 99.55 | AAK74935 |
| ONEGGOAA_1 | 783014 | 783685 | ciaR | 4.81e-119 | two component system response regulator | 83.93 | 99.12 | AIK75708 |
| ONEGGOAA_1 | 297830 | 298516 | CovR | 1.02e-117 | serves to repress GAS virulence factor-encoding genes | 80.79 | 100.00 | ACE75886 |
| ONEGGOAA_1 | 66883 | 67278 | SpxA2 | 3.74e-74 | transcriptional regulator | 90.91 | 100.00 | ERL21461 |
| ONEGGOAA_1 | 937678 | 938079 | SpxA1 | 3.80e-66 | transcriptional regulator | 80.60 | 100.00 | ERL19273 |
| ONEGGOAA_1 | 150378 | 150878 | RopE (M5005_Spy_1611) | 9.98e-75 | probable DNA-directed RNA polymerase subunit delta | 80.84 | 87.43 | AAK34603 |
| ONEGGOAA_1 | 1546014 | 1548311 | PFL (B9H01_RS01125) | 0.0 | formate C-acetyltransferase | 83.07 | 98.08 | MYN69560 |
| ONEGGOAA_1 | 1748898 | 1747879 | ilvC (SPD_0406) | 0.0 | ketol-acid reductoisomerase (NADP(+)) | 96.47 | 100.00 | ABJ55451 |
BLASTX v2.16.0 (Database: PHI base v4.16, May. 2024 release)
Plasmid
PlasmidFinder
| Query ID | Begin | End | Plasmid | Query / Template | Identity | Accession no. |
|---|---|---|---|---|---|---|
| No hit found | ||||||
PlasmidFinder v 2.1.6 (Database: plasmidfinder_db v 2.2.0 , Nov. 2024 release)
PlasmidHunter
| Query ID | Prediction | Chromosome | Plasmid |
|---|---|---|---|
| ONEGGOAA_1 | 0.0 | 1.0 | 0.0 |
PlasmidHunter v 1.4.5 (Database: May. 2024 release)
Prophage
Phigaro
| Query ID | Begin | End | Transposable | Taxonomy | pVOGs |
|---|---|---|---|---|---|
| No hit found | |||||
Phigaro v2.4.0 (Database: Jan. 2024 release)