Probiotic potential risk score
| ARGs | VFs | PGs | PPRS |
|---|---|---|---|
| 0 | 22 | 30 | 37.20 |
PPRS is classified as low-risk (≤4), medium-risk (4-6), and high-risk (≥6).
Antibiotic resistance genes
Comprehensive Antibiotic Resistance Database (CARD)
| Query ID | Begin | End | ARO name | ARO accession | CARD name | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
RGI v6.0.3 (Database: CARD Variants v4.0.2, Nov. 2023 release)
ResFinder
| Query ID | Begin | End | Resistance gene | Phenotype | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|
| No hit found | |||||||
ResFinder v4.6.0 (Database: resfinder_db, Aug. 2024 release)
AMRFinderPlus
| Query ID | Begin | End | Gene symbol | Sequence name | Method | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
AMRFinderPlus v4.0.3 (Database: Oct. 2024 release)
Virulence factors
Virulence Factor Database (VFDB)
| Query ID | qstart | qend | Gene name | e-value | VF name | VF category | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|---|
| BKKIGPLG_1 | 1363836 | 1365095 | STER_RS07100 | 0.0 | Capsule | Immune modulation | 99.84 | 100.00 | WP_011681445 |
| BKKIGPLG_1 | 1149436 | 1150029 | STR_RS05880 | 0.0 | Capsule | Immune modulation | 99.50 | 100.00 | WP_011226149 |
| BKKIGPLG_1 | 1362863 | 1363839 | STER_RS07095 | 0.0 | Capsule | Immune modulation | 99.49 | 99.90 | WP_011681444 |
| BKKIGPLG_1 | 914855 | 916513 | fbp54 | 0.0 | FBPs | Adherence | 99.46 | 100.00 | WP_011227179 |
| BKKIGPLG_1 | 1149436 | 1150029 | STER_RS06030 | 0.0 | Capsule | Immune modulation | 99.33 | 100.00 | WP_011226149 |
| BKKIGPLG_1 | 1149436 | 1150029 | STU_RS15260 | 0.0 | Capsule | Immune modulation | 99.33 | 100.00 | WP_011226149 |
| BKKIGPLG_1 | 1361877 | 1362845 | STER_RS07090 | 0.0 | Capsule | Immune modulation | 99.28 | 100.00 | WP_011681443 |
| BKKIGPLG_1 | 1150029 | 1150898 | rfbA | 0.0 | Capsule | Immune modulation | 99.19 | 100.00 | WP_011681286 |
| BKKIGPLG_1 | 1038036 | 1038767 | STU_RS14645 | 0.0 | Capsule | Immune modulation | 99.04 | 100.00 | WP_011226048 |
| BKKIGPLG_1 | 1036585 | 1037325 | STER_RS05305 | 0.0 | Capsule | Immune modulation | 98.92 | 100.00 | WP_011681174 |
| BKKIGPLG_1 | 1038036 | 1038767 | STR_RS05260 | 0.0 | Capsule | Immune modulation | 98.91 | 100.00 | WP_011227248 |
| BKKIGPLG_1 | 1184794 | 1185555 | srtA | 0.0 | Sortase A | Exoenzyme | 98.82 | 100.00 | - |
| BKKIGPLG_1 | 1038036 | 1038767 | STER_RS05315 | 0.0 | Capsule | Immune modulation | 98.77 | 100.00 | WP_011681176 |
| BKKIGPLG_1 | 1036585 | 1037325 | STU_RS14635 | 0.0 | Capsule | Immune modulation | 98.52 | 100.00 | WP_011226046 |
| BKKIGPLG_1 | 1104618 | 1105407 | cshA | 0.0 | Cell surface hydrophobicity proteins | Adherence | 98.48 | 99.87 | - |
| BKKIGPLG_1 | 1361160 | 1361875 | STER_RS07085 | 0.0 | Capsule | Immune modulation | 98.46 | 99.86 | WP_011681442 |
| BKKIGPLG_1 | 1036590 | 1037325 | STR_RS05250 | 0.0 | Capsule | Immune modulation | 98.37 | 98.13 | WP_011227246 |
| BKKIGPLG_1 | 1038768 | 1040228 | STER_RS05320 | 0.0 | Capsule | Immune modulation | 97.88 | 100.00 | WP_011681177 |
| BKKIGPLG_1 | 1038768 | 1040228 | STU_RS14650 | 0.0 | Capsule | Immune modulation | 97.26 | 100.21 | WP_011226049 |
| BKKIGPLG_1 | 1360044 | 1360814 | STER_RS07075 | 0.0 | Capsule | Immune modulation | 97.15 | 99.10 | WP_011681440 |
| BKKIGPLG_1 | 1038768 | 1040228 | STR_RS05265 | 0.0 | Capsule | Immune modulation | 97.12 | 100.21 | WP_041827043 |
| BKKIGPLG_1 | 634483 | 639378 | SAG_RS09105 | 0.0 | Agglutinin receptor | Adherence | 96.94 | 100.00 | WP_000167699 |
| BKKIGPLG_1 | 1365214 | 1366065 | rfbD | 0.0 | Capsule | Immune modulation | 96.24 | 100.00 | WP_014621820 |
| BKKIGPLG_1 | 634435 | 639378 | SSU98_0978 | 0.0 | Agglutinin receptor | Adherence | 95.77 | 99.82 | YP_001200536 |
| BKKIGPLG_1 | 634435 | 639378 | SSU05_0965 | 0.0 | Agglutinin receptor | Adherence | 95.75 | 99.82 | YP_001198331 |
| BKKIGPLG_1 | 1035164 | 1036529 | STER_RS05300 | 0.0 | Capsule | Immune modulation | 94.88 | 99.85 | WP_011681173 |
| BKKIGPLG_1 | 1037335 | 1038027 | STR_RS05255 | 0.0 | Capsule | Immune modulation | 94.37 | 100.00 | WP_011227247 |
| BKKIGPLG_1 | 1037335 | 1038027 | STU_RS14640 | 0.0 | Capsule | Immune modulation | 94.37 | 100.00 | WP_011226047 |
| BKKIGPLG_1 | 1035162 | 1036529 | STU_RS14630 | 0.0 | Capsule | Immune modulation | 93.93 | 100.00 | WP_011226045 |
| BKKIGPLG_1 | 1037335 | 1038027 | STER_RS05310 | 0.0 | Capsule | Immune modulation | 90.62 | 100.00 | WP_011681175 |
| BKKIGPLG_1 | 599743 | 601046 | eno | 0.0 | Streptococcal enolase | Exoenzyme | 88.17 | 99.54 | WP_000022832 |
| BKKIGPLG_1 | 42416 | 43255 | cbpD | 0.0 | Autolysin | Exoenzyme | 87.31 | 99.76 | WP_011226733 |
| BKKIGPLG_1 | 1646872 | 1647882 | plr/gapA | 0.0 | Streptococcal plasmin receptor/GAPDH | Adherence | 86.73 | 99.51 | WP_002986042 |
| BKKIGPLG_1 | 1147960 | 1149006 | rfbB | 0.0 | Capsule | Immune modulation | 80.61 | 100.00 | WP_009659423 |
| BKKIGPLG_1 | 149509 | 150792 | tig/ropA | 0.0 | Trigger factor | Stress survival | 80.58 | 99.77 | WP_000107753 |
BLASTN v2.16.0 (Database: VFDB, Dec. 2024 release)
VirulenceFinder
| Query ID | Begin | End | Database | Virulence factor | Protein function | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
VirulenceFinder v2.0. 4 (Database: virulencefinder_db, Feb . 2024 release)
Pathogenic genes
PHI-base
| Query ID | qstart | qend | Gene name | e-value | Function | Identity | Coverage | Gene ID |
|---|---|---|---|---|---|---|---|---|
| BKKIGPLG_1 | 634462 | 639375 | B9H01_RS04765 | 0.0 | glucan-binding protein | 96.34 | 99.70 | AUS90958 |
| BKKIGPLG_1 | 1188242 | 1189225 | ldh(Sp_1220) | 0.0 | L-lactate dehydrogenase | 94.82 | 100.00 | AAK75326 |
| BKKIGPLG_1 | 762326 | 763399 | MntE | 0.0 | manganese homeostasis | 94.41 | 99.72 | ABF32167 |
| BKKIGPLG_1 | 514118 | 515086 | spr0084 | 0.0 | pathogenitcity related | 93.19 | 98.48 | AAK98888 |
| BKKIGPLG_1 | 1522803 | 1525106 | pfl2(Sp_0459) | 0.0 | formate acetyltransferase | 92.97 | 99.22 | AAK74619 |
| BKKIGPLG_1 | 790767 | 793013 | metE | 0.0 | methionine biosynthesis enzymes | 91.99 | 100.00 | AAK74738 |
| BKKIGPLG_1 | 1265737 | 1267218 | SPD_0310 | 0.0 | UPF0371 protein SPD_0310 | 91.70 | 100.00 | ABJ54480 |
| BKKIGPLG_1 | 63747 | 64745 | recA | 0.0 | DNA recombination and repair | 91.29 | 85.82 | AAL00560 |
| BKKIGPLG_1 | 27143 | 28114 | prsA2 | 0.0 | ribose-phosphate pyrophosphokinase | 89.81 | 100.00 | ABF36968 |
| BKKIGPLG_1 | 1407456 | 1406305 | potA | 0.0 | ABC transporter ATP-binding protein-spermidine/putrescine transport | 89.32 | 99.74 | AAL00050 |
| BKKIGPLG_1 | 1379455 | 1377467 | uvrB | 0.0 | excinuclease ABC, B subunit | 88.99 | 100.00 | AE014259_2 |
| BKKIGPLG_1 | 1172046 | 1170316 | ptsI | 0.0 | phosphoenolpyruvate-protein phosphotransferase | 87.69 | 100.00 | AAK34199 |
| BKKIGPLG_1 | 1865952 | 1864474 | IMPDH | 0.0 | inosine-5'-monophosphate dehydrogenase | 87.63 | 100.00 | ADE32434 |
| BKKIGPLG_1 | 599743 | 601044 | Eno | 0.0 | enolase | 86.21 | 99.77 | ABP90468 |
| BKKIGPLG_1 | 1850757 | 1848865 | gidA | 0.0 | tRNA uridine 5-carboxymethylaminomethyl modification enzyme | 86.05 | 98.90 | ABP91129 |
| BKKIGPLG_1 | 795938 | 794229 | PGM | 0.0 | phosphoglucomutase | 83.89 | 99.65 | ACH87041 |
| BKKIGPLG_1 | 1690269 | 1691279 | pdh | 0.0 | pyruvate dehydrogenase | 83.09 | 99.70 | ABP91006 |
| BKKIGPLG_1 | 940826 | 939465 | mnmE | 0.0 | central tRNA-modifying GTPase | 82.02 | 99.56 | ABP90420 |
| BKKIGPLG_1 | 1740529 | 1738637 | PepO | 0.0 | endopeptidase | 80.03 | 100.00 | ABF32980 |
| BKKIGPLG_1 | 585312 | 586202 | bglB | 1.35e-178 | putative phospho--glucosidase | 88.89 | 99.66 | AAK33487 |
| BKKIGPLG_1 | 857860 | 856922 | SP_0676 | 8.32e-168 | transcription facot | 81.47 | 97.20 | AAK74821 |
| BKKIGPLG_1 | 793205 | 794062 | metF | 8.76e-165 | methionine biosynthesis enzymes | 86.36 | 99.31 | AAK74739 |
| BKKIGPLG_1 | 1076937 | 1076233 | covR | 1.08e-130 | responder protein | 85.11 | 100.00 | AAK71319 |
| BKKIGPLG_1 | 1233585 | 1232914 | rr01 | 4.89e-126 | response regulator | 84.82 | 99.56 | CAB54566 |
| BKKIGPLG_1 | 1076937 | 1076233 | walR | 5.41e-121 | DNA-binding response regulator | 81.28 | 100.00 | ANC99504 |
| BKKIGPLG_1 | 799892 | 800560 | CiaR | 1.24e-118 | two-component response regulator | 84.75 | 99.55 | AAK74935 |
| BKKIGPLG_1 | 299959 | 300645 | CovR | 1.02e-117 | serves to repress GAS virulence factor-encoding genes | 80.79 | 100.00 | ACE75886 |
| BKKIGPLG_1 | 799892 | 800563 | ciaR | 1.12e-116 | two component system response regulator | 82.59 | 99.12 | AIK75708 |
| BKKIGPLG_1 | 65021 | 65416 | SpxA2 | 3.75e-74 | transcriptional regulator | 90.91 | 100.00 | ERL21461 |
| BKKIGPLG_1 | 952187 | 952588 | SpxA1 | 3.81e-66 | transcriptional regulator | 80.60 | 100.00 | ERL19273 |
| BKKIGPLG_1 | 150950 | 151450 | RopE (M5005_Spy_1611) | 4.98e-75 | probable DNA-directed RNA polymerase subunit delta | 81.44 | 87.43 | AAK34603 |
| BKKIGPLG_1 | 1522803 | 1525100 | PFL (B9H01_RS01125) | 0.0 | formate C-acetyltransferase | 82.94 | 98.08 | MYN69560 |
| BKKIGPLG_1 | 1726129 | 1725110 | ilvC (SPD_0406) | 0.0 | ketol-acid reductoisomerase (NADP(+)) | 96.18 | 100.00 | ABJ55451 |
BLASTX v2.16.0 (Database: PHI base v4.16, May. 2024 release)
Plasmid
PlasmidFinder
| Query ID | Begin | End | Plasmid | Query / Template | Identity | Accession no. |
|---|---|---|---|---|---|---|
| No hit found | ||||||
PlasmidFinder v 2.1.6 (Database: plasmidfinder_db v 2.2.0 , Nov. 2024 release)
PlasmidHunter
| Query ID | Prediction | Chromosome | Plasmid |
|---|---|---|---|
| BKKIGPLG_1 | 0.0 | 1.0 | 0.0 |
PlasmidHunter v 1.4.5 (Database: May. 2024 release)
Prophage
Phigaro
| Query ID | Begin | End | Transposable | Taxonomy | pVOGs |
|---|---|---|---|---|---|
| No hit found | |||||
Phigaro v2.4.0 (Database: Jan. 2024 release)