Probiotic potential risk score
| ARGs | VFs | PGs | PPRS |
|---|---|---|---|
| 0 | 22 | 30 | 37.20 |
PPRS is classified as low-risk (≤4), medium-risk (4-6), and high-risk (≥6).
Antibiotic resistance genes
Comprehensive Antibiotic Resistance Database (CARD)
| Query ID | Begin | End | ARO name | ARO accession | CARD name | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
RGI v6.0.3 (Database: CARD Variants v4.0.2, Nov. 2023 release)
ResFinder
| Query ID | Begin | End | Resistance gene | Phenotype | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|
| No hit found | |||||||
ResFinder v4.6.0 (Database: resfinder_db, Aug. 2024 release)
AMRFinderPlus
| Query ID | Begin | End | Gene symbol | Sequence name | Method | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
AMRFinderPlus v4.0.3 (Database: Oct. 2024 release)
Virulence factors
Virulence Factor Database (VFDB)
| Query ID | qstart | qend | Gene name | e-value | VF name | VF category | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|---|
| FKNCJPLF_1 | 1366400 | 1367659 | STER_RS07100 | 0.0 | Capsule | Immune modulation | 100.00 | 100.00 | WP_011681445 |
| FKNCJPLF_1 | 1132774 | 1133367 | STR_RS05880 | 0.0 | Capsule | Immune modulation | 100.00 | 100.00 | WP_011226149 |
| FKNCJPLF_1 | 43634 | 44473 | cbpD | 0.0 | Autolysin | Exoenzyme | 99.88 | 100.00 | WP_011226733 |
| FKNCJPLF_1 | 1132774 | 1133367 | STER_RS06030 | 0.0 | Capsule | Immune modulation | 99.83 | 100.00 | WP_011226149 |
| FKNCJPLF_1 | 1132774 | 1133367 | STU_RS15260 | 0.0 | Capsule | Immune modulation | 99.83 | 100.00 | WP_011226149 |
| FKNCJPLF_1 | 1365427 | 1366403 | STER_RS07095 | 0.0 | Capsule | Immune modulation | 99.59 | 99.90 | WP_011681444 |
| FKNCJPLF_1 | 914663 | 916321 | fbp54 | 0.0 | FBPs | Adherence | 99.52 | 100.00 | WP_011227179 |
| FKNCJPLF_1 | 1364441 | 1365409 | STER_RS07090 | 0.0 | Capsule | Immune modulation | 99.28 | 100.00 | WP_011681443 |
| FKNCJPLF_1 | 1168133 | 1168894 | srtA | 0.0 | Sortase A | Exoenzyme | 99.21 | 100.00 | - |
| FKNCJPLF_1 | 1133367 | 1134236 | rfbA | 0.0 | Capsule | Immune modulation | 99.08 | 100.00 | WP_011681286 |
| FKNCJPLF_1 | 1087953 | 1088743 | cshA | 0.0 | Cell surface hydrophobicity proteins | Adherence | 98.99 | 100.00 | - |
| FKNCJPLF_1 | 1021553 | 1022284 | STR_RS05260 | 0.0 | Capsule | Immune modulation | 98.50 | 100.00 | WP_011227248 |
| FKNCJPLF_1 | 1022285 | 1023745 | STER_RS05320 | 0.0 | Capsule | Immune modulation | 98.49 | 100.00 | WP_011681177 |
| FKNCJPLF_1 | 1363724 | 1364439 | STER_RS07085 | 0.0 | Capsule | Immune modulation | 98.32 | 99.86 | WP_011681442 |
| FKNCJPLF_1 | 1362608 | 1363378 | STER_RS07075 | 0.0 | Capsule | Immune modulation | 98.18 | 99.23 | WP_011681440 |
| FKNCJPLF_1 | 1021553 | 1022284 | STU_RS14645 | 0.0 | Capsule | Immune modulation | 97.81 | 100.00 | WP_011226048 |
| FKNCJPLF_1 | 1021553 | 1022284 | STER_RS05315 | 0.0 | Capsule | Immune modulation | 97.54 | 100.00 | WP_011681176 |
| FKNCJPLF_1 | 1022285 | 1023745 | STU_RS14650 | 0.0 | Capsule | Immune modulation | 97.47 | 100.21 | WP_011226049 |
| FKNCJPLF_1 | 1367778 | 1368629 | rfbD | 0.0 | Capsule | Immune modulation | 97.30 | 100.00 | WP_014621820 |
| FKNCJPLF_1 | 642961 | 647856 | SAG_RS09105 | 0.0 | Agglutinin receptor | Adherence | 96.89 | 100.00 | WP_000167699 |
| FKNCJPLF_1 | 1020102 | 1020842 | STER_RS05305 | 0.0 | Capsule | Immune modulation | 96.76 | 100.00 | WP_011681174 |
| FKNCJPLF_1 | 1022285 | 1023745 | STR_RS05265 | 0.0 | Capsule | Immune modulation | 96.65 | 100.21 | WP_041827043 |
| FKNCJPLF_1 | 1020102 | 1020842 | STU_RS14635 | 0.0 | Capsule | Immune modulation | 96.49 | 100.00 | WP_011226046 |
| FKNCJPLF_1 | 1020107 | 1020842 | STR_RS05250 | 0.0 | Capsule | Immune modulation | 96.20 | 98.13 | WP_011227246 |
| FKNCJPLF_1 | 1020852 | 1021544 | STR_RS05255 | 0.0 | Capsule | Immune modulation | 95.81 | 100.00 | WP_011227247 |
| FKNCJPLF_1 | 1020852 | 1021544 | STU_RS14640 | 0.0 | Capsule | Immune modulation | 95.81 | 100.00 | WP_011226047 |
| FKNCJPLF_1 | 642913 | 647856 | SSU98_0978 | 0.0 | Agglutinin receptor | Adherence | 95.81 | 99.82 | YP_001200536 |
| FKNCJPLF_1 | 642913 | 647856 | SSU05_0965 | 0.0 | Agglutinin receptor | Adherence | 95.79 | 99.82 | YP_001198331 |
| FKNCJPLF_1 | 1018678 | 1020045 | STU_RS14630 | 0.0 | Capsule | Immune modulation | 95.61 | 100.00 | WP_011226045 |
| FKNCJPLF_1 | 1018680 | 1020045 | STER_RS05300 | 0.0 | Capsule | Immune modulation | 94.29 | 99.85 | WP_011681173 |
| FKNCJPLF_1 | 1020852 | 1021544 | STER_RS05310 | 0.0 | Capsule | Immune modulation | 89.75 | 100.00 | WP_011681175 |
| FKNCJPLF_1 | 608219 | 609522 | eno | 0.0 | Streptococcal enolase | Exoenzyme | 88.09 | 99.54 | WP_000022832 |
| FKNCJPLF_1 | 1670978 | 1671988 | plr/gapA | 0.0 | Streptococcal plasmin receptor/GAPDH | Adherence | 86.92 | 99.51 | WP_002986042 |
| FKNCJPLF_1 | 144949 | 146232 | tig/ropA | 0.0 | Trigger factor | Stress survival | 80.65 | 99.77 | WP_000107753 |
| FKNCJPLF_1 | 1131299 | 1132345 | rfbB | 0.0 | Capsule | Immune modulation | 80.61 | 100.00 | WP_009659423 |
BLASTN v2.16.0 (Database: VFDB, Dec. 2024 release)
VirulenceFinder
| Query ID | Begin | End | Database | Virulence factor | Protein function | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
VirulenceFinder v2.0. 4 (Database: virulencefinder_db, Feb . 2024 release)
Pathogenic genes
PHI-base
| Query ID | qstart | qend | Gene name | e-value | Function | Identity | Coverage | Gene ID |
|---|---|---|---|---|---|---|---|---|
| FKNCJPLF_1 | 642940 | 647853 | B9H01_RS04765 | 0.0 | glucan-binding protein | 96.40 | 99.70 | AUS90958 |
| FKNCJPLF_1 | 1171581 | 1172564 | ldh(Sp_1220) | 0.0 | L-lactate dehydrogenase | 94.82 | 100.00 | AAK75326 |
| FKNCJPLF_1 | 774797 | 775870 | MntE | 0.0 | manganese homeostasis | 94.13 | 99.72 | ABF32167 |
| FKNCJPLF_1 | 524663 | 525631 | spr0084 | 0.0 | pathogenitcity related | 93.19 | 98.48 | AAK98888 |
| FKNCJPLF_1 | 1548405 | 1550708 | pfl2(Sp_0459) | 0.0 | formate acetyltransferase | 93.10 | 99.22 | AAK74619 |
| FKNCJPLF_1 | 1264831 | 1266312 | SPD_0310 | 0.0 | UPF0371 protein SPD_0310 | 92.11 | 100.00 | ABJ54480 |
| FKNCJPLF_1 | 795319 | 797565 | metE | 0.0 | methionine biosynthesis enzymes | 91.99 | 100.00 | AAK74738 |
| FKNCJPLF_1 | 63264 | 64262 | recA | 0.0 | DNA recombination and repair | 91.29 | 85.82 | AAL00560 |
| FKNCJPLF_1 | 27151 | 28122 | prsA2 | 0.0 | ribose-phosphate pyrophosphokinase | 90.12 | 100.00 | ABF36968 |
| FKNCJPLF_1 | 1418540 | 1417389 | potA | 0.0 | ABC transporter ATP-binding protein-spermidine/putrescine transport | 89.32 | 99.74 | AAL00050 |
| FKNCJPLF_1 | 1381668 | 1379680 | uvrB | 0.0 | excinuclease ABC, B subunit | 88.99 | 100.00 | AE014259_2 |
| FKNCJPLF_1 | 1155385 | 1153655 | ptsI | 0.0 | phosphoenolpyruvate-protein phosphotransferase | 88.04 | 100.00 | AAK34199 |
| FKNCJPLF_1 | 1860023 | 1858545 | IMPDH | 0.0 | inosine-5'-monophosphate dehydrogenase | 87.63 | 100.00 | ADE32434 |
| FKNCJPLF_1 | 608219 | 609520 | Eno | 0.0 | enolase | 86.21 | 99.77 | ABP90468 |
| FKNCJPLF_1 | 1844800 | 1842908 | gidA | 0.0 | tRNA uridine 5-carboxymethylaminomethyl modification enzyme | 86.05 | 98.90 | ABP91129 |
| FKNCJPLF_1 | 800490 | 798781 | PGM | 0.0 | phosphoglucomutase | 83.89 | 99.65 | ACH87041 |
| FKNCJPLF_1 | 1712950 | 1713960 | pdh | 0.0 | pyruvate dehydrogenase | 83.09 | 99.70 | ABP91006 |
| FKNCJPLF_1 | 941522 | 940161 | mnmE | 0.0 | central tRNA-modifying GTPase | 82.24 | 99.56 | ABP90420 |
| FKNCJPLF_1 | 1763270 | 1761378 | PepO | 0.0 | endopeptidase | 80.19 | 100.00 | ABF32980 |
| FKNCJPLF_1 | 593790 | 594680 | bglB | 5.51e-178 | putative phospho--glucosidase | 88.55 | 99.66 | AAK33487 |
| FKNCJPLF_1 | 859916 | 858978 | SP_0676 | 8.29e-168 | transcription facot | 81.47 | 97.20 | AAK74821 |
| FKNCJPLF_1 | 797757 | 798614 | metF | 8.73e-165 | methionine biosynthesis enzymes | 86.36 | 99.31 | AAK74739 |
| FKNCJPLF_1 | 1060312 | 1059608 | covR | 6.83e-131 | responder protein | 85.53 | 100.00 | AAK71319 |
| FKNCJPLF_1 | 1237224 | 1236553 | rr01 | 4.22e-125 | response regulator | 84.38 | 99.56 | CAB54566 |
| FKNCJPLF_1 | 1060312 | 1059608 | walR | 3.23e-121 | DNA-binding response regulator | 81.70 | 100.00 | ANC99504 |
| FKNCJPLF_1 | 293879 | 294565 | CovR | 1.02e-117 | serves to repress GAS virulence factor-encoding genes | 80.79 | 100.00 | ACE75886 |
| FKNCJPLF_1 | 804444 | 805112 | CiaR | 7.17e-117 | two-component response regulator | 83.86 | 99.55 | AAK74935 |
| FKNCJPLF_1 | 804444 | 805115 | ciaR | 7.13e-115 | two component system response regulator | 81.70 | 99.12 | AIK75708 |
| FKNCJPLF_1 | 64538 | 64933 | SpxA2 | 3.74e-74 | transcriptional regulator | 90.91 | 100.00 | ERL21461 |
| FKNCJPLF_1 | 952679 | 953080 | SpxA1 | 3.80e-66 | transcriptional regulator | 80.60 | 100.00 | ERL19273 |
| FKNCJPLF_1 | 146390 | 146890 | RopE (M5005_Spy_1611) | 9.97e-75 | probable DNA-directed RNA polymerase subunit delta | 80.84 | 87.43 | AAK34603 |
| FKNCJPLF_1 | 1548405 | 1550702 | PFL (B9H01_RS01125) | 0.0 | formate C-acetyltransferase | 83.07 | 98.08 | MYN69560 |
| FKNCJPLF_1 | 1748813 | 1747794 | ilvC (SPD_0406) | 0.0 | ketol-acid reductoisomerase (NADP(+)) | 96.47 | 100.00 | ABJ55451 |
BLASTX v2.16.0 (Database: PHI base v4.16, May. 2024 release)
Plasmid
PlasmidFinder
| Query ID | Begin | End | Plasmid | Query / Template | Identity | Accession no. |
|---|---|---|---|---|---|---|
| No hit found | ||||||
PlasmidFinder v 2.1.6 (Database: plasmidfinder_db v 2.2.0 , Nov. 2024 release)
PlasmidHunter
| Query ID | Prediction | Chromosome | Plasmid |
|---|---|---|---|
| FKNCJPLF_1 | 0.0 | 1.0 | 0.0 |
PlasmidHunter v 1.4.5 (Database: May. 2024 release)
Prophage
Phigaro
| Query ID | Begin | End | Transposable | Taxonomy | pVOGs |
|---|---|---|---|---|---|
| FKNCJPLF_1 | 664782 | 667671 | False | Unknown | VOG9403, VOG9404, VOG6396, VOG6396, VOG9405 |
Phigaro v2.4.0 (Database: Jan. 2024 release)