Probiotic potential risk score
| ARGs | VFs | PGs | PPRS |
|---|---|---|---|
| 0 | 18 | 29 | 34.13 |
PPRS is classified as low-risk (≤4), medium-risk (4-6), and high-risk (≥6).
Antibiotic resistance genes
Comprehensive Antibiotic Resistance Database (CARD)
| Query ID | Begin | End | ARO name | ARO accession | CARD name | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
RGI v6.0.3 (Database: CARD Variants v4.0.2, Nov. 2023 release)
ResFinder
| Query ID | Begin | End | Resistance gene | Phenotype | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|
| No hit found | |||||||
ResFinder v4.6.0 (Database: resfinder_db, Aug. 2024 release)
AMRFinderPlus
| Query ID | Begin | End | Gene symbol | Sequence name | Method | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
AMRFinderPlus v4.0.3 (Database: Oct. 2024 release)
Virulence factors
Virulence Factor Database (VFDB)
| Query ID | qstart | qend | Gene name | e-value | VF name | VF category | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|---|
| BEMHMKMP_1 | 1129517 | 1130386 | rfbA | 0.0 | Capsule | Immune modulation | 100.00 | 100.00 | WP_011681286 |
| BEMHMKMP_1 | 1128924 | 1129517 | STER_RS06030 | 0.0 | Capsule | Immune modulation | 100.00 | 100.00 | WP_011226149 |
| BEMHMKMP_1 | 1128924 | 1129517 | STR_RS05880 | 0.0 | Capsule | Immune modulation | 99.83 | 100.00 | WP_011226149 |
| BEMHMKMP_1 | 1128924 | 1129517 | STU_RS15260 | 0.0 | Capsule | Immune modulation | 99.66 | 100.00 | WP_011226149 |
| BEMHMKMP_1 | 902701 | 904359 | fbp54 | 0.0 | FBPs | Adherence | 99.58 | 100.00 | WP_011227179 |
| BEMHMKMP_1 | 44929 | 45768 | cbpD | 0.0 | Autolysin | Exoenzyme | 99.52 | 100.00 | WP_011226733 |
| BEMHMKMP_1 | 1007332 | 1008063 | STER_RS05315 | 0.0 | Capsule | Immune modulation | 98.77 | 100.00 | WP_011681176 |
| BEMHMKMP_1 | 1074031 | 1074819 | cshA | 0.0 | Cell surface hydrophobicity proteins | Adherence | 98.36 | 99.75 | - |
| BEMHMKMP_1 | 1360005 | 1360721 | STER_RS07085 | 0.0 | Capsule | Immune modulation | 98.33 | 100.00 | WP_011681442 |
| BEMHMKMP_1 | 1007332 | 1008063 | STU_RS14645 | 0.0 | Capsule | Immune modulation | 98.09 | 100.00 | WP_011226048 |
| BEMHMKMP_1 | 1007332 | 1008063 | STR_RS05260 | 0.0 | Capsule | Immune modulation | 97.81 | 100.00 | WP_011227248 |
| BEMHMKMP_1 | 1005881 | 1006621 | STER_RS05305 | 0.0 | Capsule | Immune modulation | 97.71 | 100.00 | WP_011681174 |
| BEMHMKMP_1 | 1366343 | 1367194 | rfbD | 0.0 | Capsule | Immune modulation | 97.65 | 100.00 | WP_014621820 |
| BEMHMKMP_1 | 1165710 | 1166471 | srtA | 0.0 | Sortase A | Exoenzyme | 97.64 | 100.00 | - |
| BEMHMKMP_1 | 1008064 | 1009519 | STER_RS05320 | 0.0 | Capsule | Immune modulation | 97.60 | 99.66 | WP_011681177 |
| BEMHMKMP_1 | 1005881 | 1006621 | STU_RS14635 | 0.0 | Capsule | Immune modulation | 97.57 | 100.00 | WP_011226046 |
| BEMHMKMP_1 | 1005886 | 1006621 | STR_RS05250 | 0.0 | Capsule | Immune modulation | 97.01 | 98.13 | WP_011227246 |
| BEMHMKMP_1 | 1008064 | 1009519 | STU_RS14650 | 0.0 | Capsule | Immune modulation | 96.84 | 99.86 | WP_011226049 |
| BEMHMKMP_1 | 1358883 | 1359659 | STER_RS07075 | 0.0 | Capsule | Immune modulation | 96.66 | 99.87 | WP_011681440 |
| BEMHMKMP_1 | 1008064 | 1009519 | STR_RS05265 | 0.0 | Capsule | Immune modulation | 96.08 | 99.86 | WP_041827043 |
| BEMHMKMP_1 | 1004459 | 1005824 | STER_RS05300 | 0.0 | Capsule | Immune modulation | 95.24 | 99.85 | WP_011681173 |
| BEMHMKMP_1 | 1004457 | 1005824 | STU_RS14630 | 0.0 | Capsule | Immune modulation | 94.30 | 100.00 | WP_011226045 |
| BEMHMKMP_1 | 1006631 | 1007323 | STU_RS14640 | 0.0 | Capsule | Immune modulation | 93.51 | 100.00 | WP_011226047 |
| BEMHMKMP_1 | 1006631 | 1007323 | STR_RS05255 | 0.0 | Capsule | Immune modulation | 93.22 | 100.00 | WP_011227247 |
| BEMHMKMP_1 | 636846 | 638149 | eno | 0.0 | Streptococcal enolase | Exoenzyme | 88.10 | 99.46 | WP_000022832 |
| BEMHMKMP_1 | 1006631 | 1007323 | STER_RS05310 | 0.0 | Capsule | Immune modulation | 87.16 | 100.00 | WP_011681175 |
| BEMHMKMP_1 | 1653924 | 1654934 | plr/gapA | 0.0 | Streptococcal plasmin receptor/GAPDH | Adherence | 86.54 | 99.41 | WP_002986042 |
| BEMHMKMP_1 | 155728 | 157011 | tig/ropA | 0.0 | Trigger factor | Stress survival | 80.65 | 99.77 | WP_000107753 |
| BEMHMKMP_1 | 1127449 | 1128495 | rfbB | 0.0 | Capsule | Immune modulation | 80.61 | 100.00 | WP_009659423 |
BLASTN v2.16.0 (Database: VFDB, Dec. 2024 release)
VirulenceFinder
| Query ID | Begin | End | Database | Virulence factor | Protein function | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
VirulenceFinder v2.0. 4 (Database: virulencefinder_db, Feb . 2024 release)
Pathogenic genes
PHI-base
| Query ID | qstart | qend | Gene name | e-value | Function | Identity | Coverage | Gene ID |
|---|---|---|---|---|---|---|---|---|
| BEMHMKMP_1 | 740127 | 741200 | MntE | 0.0 | manganese homeostasis | 94.41 | 99.72 | ABF32167 |
| BEMHMKMP_1 | 553161 | 554129 | spr0084 | 0.0 | pathogenitcity related | 93.19 | 98.48 | AAK98888 |
| BEMHMKMP_1 | 1531002 | 1533305 | pfl2(Sp_0459) | 0.0 | formate acetyltransferase | 92.97 | 99.22 | AAK74619 |
| BEMHMKMP_1 | 776688 | 778934 | metE | 0.0 | methionine biosynthesis enzymes | 91.99 | 100.00 | AAK74738 |
| BEMHMKMP_1 | 1249505 | 1250986 | SPD_0310 | 0.0 | UPF0371 protein SPD_0310 | 91.90 | 100.00 | ABJ54480 |
| BEMHMKMP_1 | 71533 | 72525 | recA | 0.0 | DNA recombination and repair | 91.24 | 85.31 | AAL00560 |
| BEMHMKMP_1 | 27199 | 28170 | prsA2 | 0.0 | ribose-phosphate pyrophosphokinase | 90.12 | 100.00 | ABF36968 |
| BEMHMKMP_1 | 1417213 | 1416062 | potA | 0.0 | ABC transporter ATP-binding protein-spermidine/putrescine transport | 89.32 | 99.74 | AAL00050 |
| BEMHMKMP_1 | 1380254 | 1378266 | uvrB | 0.0 | excinuclease ABC, B subunit | 88.99 | 100.00 | AE014259_2 |
| BEMHMKMP_1 | 1152961 | 1151231 | ptsI | 0.0 | phosphoenolpyruvate-protein phosphotransferase | 88.04 | 100.00 | AAK34199 |
| BEMHMKMP_1 | 1848918 | 1847440 | IMPDH | 0.0 | inosine-5'-monophosphate dehydrogenase | 87.42 | 100.00 | ADE32434 |
| BEMHMKMP_1 | 636846 | 638147 | Eno | 0.0 | enolase | 86.21 | 99.77 | ABP90468 |
| BEMHMKMP_1 | 1833730 | 1831838 | gidA | 0.0 | tRNA uridine 5-carboxymethylaminomethyl modification enzyme | 86.05 | 98.90 | ABP91129 |
| BEMHMKMP_1 | 781859 | 780150 | PGM | 0.0 | phosphoglucomutase | 84.06 | 99.65 | ACH87041 |
| BEMHMKMP_1 | 1695915 | 1696925 | pdh | 0.0 | pyruvate dehydrogenase | 83.09 | 99.70 | ABP91006 |
| BEMHMKMP_1 | 926246 | 924996 | mnmE | 0.0 | central tRNA-modifying GTPase | 80.91 | 91.47 | ABP90420 |
| BEMHMKMP_1 | 1746154 | 1744262 | PepO | 0.0 | endopeptidase | 80.03 | 100.00 | ABF32980 |
| BEMHMKMP_1 | 622411 | 623301 | bglB | 5.27e-178 | putative phospho--glucosidase | 88.55 | 99.66 | AAK33487 |
| BEMHMKMP_1 | 1169349 | 1170140 | ldh(Sp_1220) | 4.15e-175 | L-lactate dehydrogenase | 95.08 | 80.49 | AAK75326 |
| BEMHMKMP_1 | 842916 | 841978 | SP_0676 | 2.36e-167 | transcription facot | 81.15 | 97.20 | AAK74821 |
| BEMHMKMP_1 | 779126 | 779983 | metF | 1.54e-164 | methionine biosynthesis enzymes | 86.36 | 99.31 | AAK74739 |
| BEMHMKMP_1 | 1046351 | 1045647 | covR | 4.40e-131 | responder protein | 85.53 | 100.00 | AAK71319 |
| BEMHMKMP_1 | 1217142 | 1216471 | rr01 | 3.02e-124 | response regulator | 83.93 | 99.56 | CAB54566 |
| BEMHMKMP_1 | 785813 | 786481 | CiaR | 2.80e-123 | two-component response regulator | 87.00 | 99.55 | AAK74935 |
| BEMHMKMP_1 | 1046351 | 1045647 | walR | 1.85e-121 | DNA-binding response regulator | 82.13 | 100.00 | ANC99504 |
| BEMHMKMP_1 | 785813 | 786484 | ciaR | 2.73e-121 | two component system response regulator | 84.82 | 99.12 | AIK75708 |
| BEMHMKMP_1 | 310114 | 310800 | CovR | 1.01e-117 | serves to repress GAS virulence factor-encoding genes | 80.79 | 100.00 | ACE75886 |
| BEMHMKMP_1 | 72837 | 73232 | SpxA2 | 3.72e-74 | transcriptional regulator | 90.91 | 100.00 | ERL21461 |
| BEMHMKMP_1 | 937714 | 938115 | SpxA1 | 3.78e-66 | transcriptional regulator | 80.60 | 100.00 | ERL19273 |
| BEMHMKMP_1 | 157169 | 157669 | RopE (M5005_Spy_1611) | 4.94e-75 | probable DNA-directed RNA polymerase subunit delta | 81.44 | 87.43 | AAK34603 |
| BEMHMKMP_1 | 1531002 | 1533299 | PFL (B9H01_RS01125) | 0.0 | formate C-acetyltransferase | 82.94 | 98.08 | MYN69560 |
| BEMHMKMP_1 | 1731777 | 1730758 | ilvC (SPD_0406) | 0.0 | ketol-acid reductoisomerase (NADP(+)) | 95.88 | 100.00 | ABJ55451 |
BLASTX v2.16.0 (Database: PHI base v4.16, May. 2024 release)
Plasmid
PlasmidFinder
| Query ID | Begin | End | Plasmid | Query / Template | Identity | Accession no. |
|---|---|---|---|---|---|---|
| No hit found | ||||||
PlasmidFinder v 2.1.6 (Database: plasmidfinder_db v 2.2.0 , Nov. 2024 release)
PlasmidHunter
| Query ID | Prediction | Chromosome | Plasmid |
|---|---|---|---|
| BEMHMKMP_1 | 0.0 | 1.0 | 0.0 |
PlasmidHunter v 1.4.5 (Database: May. 2024 release)
Prophage
Phigaro
| Query ID | Begin | End | Transposable | Taxonomy | pVOGs |
|---|---|---|---|---|---|
| No hit found | |||||
Phigaro v2.4.0 (Database: Jan. 2024 release)