Probiotic potential risk score
| ARGs | VFs | PGs | PPRS |
|---|---|---|---|
| 0 | 26 | 29 | 38.95 |
PPRS is classified as low-risk (≤4), medium-risk (4-6), and high-risk (≥6).
Antibiotic resistance genes
Comprehensive Antibiotic Resistance Database (CARD)
| Query ID | Begin | End | ARO name | ARO accession | CARD name | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
RGI v6.0.3 (Database: CARD Variants v4.0.2, Nov. 2023 release)
ResFinder
| Query ID | Begin | End | Resistance gene | Phenotype | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|
| No hit found | |||||||
ResFinder v4.6.0 (Database: resfinder_db, Aug. 2024 release)
AMRFinderPlus
| Query ID | Begin | End | Gene symbol | Sequence name | Method | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
AMRFinderPlus v4.0.3 (Database: Oct. 2024 release)
Virulence factors
Virulence Factor Database (VFDB)
| Query ID | qstart | qend | Gene name | e-value | VF name | VF category | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|---|
| BPLBJJKO_1 | 1135956 | 1136825 | rfbA | 0.0 | Capsule | Immune modulation | 100.00 | 100.00 | WP_011681286 |
| BPLBJJKO_1 | 1135363 | 1135956 | STER_RS06030 | 0.0 | Capsule | Immune modulation | 100.00 | 100.00 | WP_011226149 |
| BPLBJJKO_1 | 1354574 | 1355542 | STER_RS07090 | 0.0 | Capsule | Immune modulation | 100.00 | 100.00 | WP_011681443 |
| BPLBJJKO_1 | 1006831 | 1007523 | STU_RS14640 | 0.0 | Capsule | Immune modulation | 100.00 | 100.00 | WP_011226047 |
| BPLBJJKO_1 | 826678 | 827301 | STU_RS14555 | 0.0 | Capsule | Immune modulation | 99.84 | 100.00 | WP_011226030 |
| BPLBJJKO_1 | 1135363 | 1135956 | STR_RS05880 | 0.0 | Capsule | Immune modulation | 99.83 | 100.00 | WP_011226149 |
| BPLBJJKO_1 | 1135363 | 1135956 | STU_RS15260 | 0.0 | Capsule | Immune modulation | 99.66 | 100.00 | WP_011226149 |
| BPLBJJKO_1 | 827412 | 828530 | STU_RS14550 | 0.0 | Capsule | Immune modulation | 99.64 | 100.00 | WP_011226029 |
| BPLBJJKO_1 | 43623 | 44462 | cbpD | 0.0 | Autolysin | Exoenzyme | 99.52 | 100.00 | WP_011226733 |
| BPLBJJKO_1 | 899092 | 900750 | fbp54 | 0.0 | FBPs | Adherence | 99.52 | 100.00 | WP_011227179 |
| BPLBJJKO_1 | 1006831 | 1007523 | STR_RS05255 | 0.0 | Capsule | Immune modulation | 99.42 | 100.00 | WP_011227247 |
| BPLBJJKO_1 | 1355560 | 1356537 | STER_RS07095 | 0.0 | Capsule | Immune modulation | 99.28 | 100.00 | WP_011681444 |
| BPLBJJKO_1 | 1172146 | 1172907 | srtA | 0.0 | Sortase A | Exoenzyme | 99.21 | 100.00 | - |
| BPLBJJKO_1 | 992088 | 993503 | STER_RS05250 | 0.0 | Capsule | Immune modulation | 98.73 | 100.00 | WP_011681165 |
| BPLBJJKO_1 | 1007532 | 1008263 | STU_RS14645 | 0.0 | Capsule | Immune modulation | 98.36 | 100.00 | WP_011226048 |
| BPLBJJKO_1 | 1353857 | 1354573 | STER_RS07085 | 0.0 | Capsule | Immune modulation | 98.19 | 100.00 | WP_011681442 |
| BPLBJJKO_1 | 1007532 | 1008263 | STER_RS05315 | 0.0 | Capsule | Immune modulation | 98.09 | 100.00 | WP_011681176 |
| BPLBJJKO_1 | 1077770 | 1078565 | cshA | 0.0 | Cell surface hydrophobicity proteins | Adherence | 97.87 | 100.51 | - |
| BPLBJJKO_1 | 1007532 | 1008263 | STR_RS05260 | 0.0 | Capsule | Immune modulation | 97.68 | 100.00 | WP_011227248 |
| BPLBJJKO_1 | 1008264 | 1009724 | STER_RS05320 | 0.0 | Capsule | Immune modulation | 97.12 | 100.00 | WP_011681177 |
| BPLBJJKO_1 | 1357911 | 1358762 | rfbD | 0.0 | Capsule | Immune modulation | 97.07 | 100.00 | WP_014621820 |
| BPLBJJKO_1 | 1352741 | 1353511 | STER_RS07075 | 0.0 | Capsule | Immune modulation | 96.89 | 99.10 | WP_011681440 |
| BPLBJJKO_1 | 1356534 | 1357792 | STER_RS07100 | 0.0 | Capsule | Immune modulation | 96.43 | 99.92 | WP_011681445 |
| BPLBJJKO_1 | 1008264 | 1009724 | STU_RS14650 | 0.0 | Capsule | Immune modulation | 96.37 | 100.21 | WP_011226049 |
| BPLBJJKO_1 | 1008264 | 1009724 | STR_RS05265 | 0.0 | Capsule | Immune modulation | 96.23 | 100.21 | WP_041827043 |
| BPLBJJKO_1 | 824312 | 825307 | STU_RS14625* | 0.0 | Capsule | Immune modulation | 94.58 | 99.90 | - |
| BPLBJJKO_1 | 1004641 | 1006006 | STER_RS05300 | 0.0 | Capsule | Immune modulation | 94.08 | 99.78 | WP_011681173 |
| BPLBJJKO_1 | 1006063 | 1006821 | STER_RS05305 | 0.0 | Capsule | Immune modulation | 94.07 | 101.75 | WP_011681174 |
| BPLBJJKO_1 | 1006063 | 1006821 | STU_RS14635 | 0.0 | Capsule | Immune modulation | 94.07 | 101.35 | WP_011226046 |
| BPLBJJKO_1 | 1006068 | 1006821 | STR_RS05250 | 0.0 | Capsule | Immune modulation | 93.37 | 99.47 | WP_011227246 |
| BPLBJJKO_1 | 1004639 | 1006006 | STU_RS14630 | 0.0 | Capsule | Immune modulation | 93.21 | 99.93 | WP_011226045 |
| BPLBJJKO_1 | 1006831 | 1007523 | STER_RS05310 | 0.0 | Capsule | Immune modulation | 89.90 | 100.00 | WP_011681175 |
| BPLBJJKO_1 | 634587 | 635890 | eno | 0.0 | Streptococcal enolase | Exoenzyme | 88.10 | 99.46 | WP_000022832 |
| BPLBJJKO_1 | 1654926 | 1655936 | plr/gapA | 0.0 | Streptococcal plasmin receptor/GAPDH | Adherence | 87.45 | 99.90 | WP_002986042 |
| BPLBJJKO_1 | 157242 | 158525 | tig/ropA | 0.0 | Trigger factor | Stress survival | 80.81 | 99.77 | WP_000107753 |
| BPLBJJKO_1 | 1133888 | 1134934 | rfbB | 0.0 | Capsule | Immune modulation | 80.61 | 100.00 | WP_009659423 |
| BPLBJJKO_1 | 825316 | 825765 | STU_RS14620 | 1.36e-175 | Capsule | Immune modulation | 91.78 | 100.00 | WP_011226042 |
| BPLBJJKO_1 | 825765 | 826072 | STU_RS14615 | 1.15e-111 | Capsule | Immune modulation | 90.91 | 63.37 | WP_011226041 |
BLASTN v2.16.0 (Database: VFDB, Dec. 2024 release)
VirulenceFinder
| Query ID | Begin | End | Database | Virulence factor | Protein function | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
VirulenceFinder v2.0. 4 (Database: virulencefinder_db, Feb . 2024 release)
Pathogenic genes
PHI-base
| Query ID | qstart | qend | Gene name | e-value | Function | Identity | Coverage | Gene ID |
|---|---|---|---|---|---|---|---|---|
| BPLBJJKO_1 | 737271 | 738344 | MntE | 0.0 | manganese homeostasis | 94.97 | 99.72 | ABF32167 |
| BPLBJJKO_1 | 1175594 | 1176577 | ldh(Sp_1220) | 0.0 | L-lactate dehydrogenase | 94.51 | 100.00 | AAK75326 |
| BPLBJJKO_1 | 1532822 | 1535125 | pfl2(Sp_0459) | 0.0 | formate acetyltransferase | 93.10 | 99.22 | AAK74619 |
| BPLBJJKO_1 | 552305 | 553273 | spr0084 | 0.0 | pathogenitcity related | 92.88 | 98.48 | AAK98888 |
| BPLBJJKO_1 | 1247357 | 1248838 | SPD_0310 | 0.0 | UPF0371 protein SPD_0310 | 92.11 | 100.00 | ABJ54480 |
| BPLBJJKO_1 | 759218 | 761464 | metE | 0.0 | methionine biosynthesis enzymes | 91.86 | 100.00 | AAK74738 |
| BPLBJJKO_1 | 75736 | 76728 | recA | 0.0 | DNA recombination and repair | 91.24 | 85.31 | AAL00560 |
| BPLBJJKO_1 | 27141 | 28112 | prsA2 | 0.0 | ribose-phosphate pyrophosphokinase | 90.12 | 100.00 | ABF36968 |
| BPLBJJKO_1 | 1409677 | 1408526 | potA | 0.0 | ABC transporter ATP-binding protein-spermidine/putrescine transport | 89.32 | 99.74 | AAL00050 |
| BPLBJJKO_1 | 1372060 | 1370072 | uvrB | 0.0 | excinuclease ABC, B subunit | 88.99 | 100.00 | AE014259_2 |
| BPLBJJKO_1 | 1159397 | 1157667 | ptsI | 0.0 | phosphoenolpyruvate-protein phosphotransferase | 87.69 | 100.00 | AAK34199 |
| BPLBJJKO_1 | 1843262 | 1841784 | IMPDH | 0.0 | inosine-5'-monophosphate dehydrogenase | 87.63 | 100.00 | ADE32434 |
| BPLBJJKO_1 | 634587 | 635888 | Eno | 0.0 | enolase | 86.21 | 99.77 | ABP90468 |
| BPLBJJKO_1 | 1828074 | 1826182 | gidA | 0.0 | tRNA uridine 5-carboxymethylaminomethyl modification enzyme | 86.05 | 98.90 | ABP91129 |
| BPLBJJKO_1 | 764389 | 762680 | PGM | 0.0 | phosphoglucomutase | 83.89 | 99.65 | ACH87041 |
| BPLBJJKO_1 | 1699762 | 1700772 | pdh | 0.0 | pyruvate dehydrogenase | 83.09 | 99.70 | ABP91006 |
| BPLBJJKO_1 | 928102 | 926741 | mnmE | 0.0 | central tRNA-modifying GTPase | 82.24 | 99.56 | ABP90420 |
| BPLBJJKO_1 | 1750120 | 1748228 | PepO | 0.0 | endopeptidase | 80.19 | 100.00 | ABF32980 |
| BPLBJJKO_1 | 620151 | 621041 | bglB | 1.33e-178 | putative phospho--glucosidase | 88.89 | 99.66 | AAK33487 |
| BPLBJJKO_1 | 833205 | 832267 | SP_0676 | 2.36e-167 | transcription facot | 81.15 | 97.20 | AAK74821 |
| BPLBJJKO_1 | 761656 | 762513 | metF | 8.65e-165 | methionine biosynthesis enzymes | 86.36 | 99.31 | AAK74739 |
| BPLBJJKO_1 | 1047981 | 1047277 | covR | 4.38e-131 | responder protein | 85.53 | 100.00 | AAK71319 |
| BPLBJJKO_1 | 1228352 | 1227681 | rr01 | 1.50e-123 | response regulator | 83.48 | 99.56 | CAB54566 |
| BPLBJJKO_1 | 768343 | 769011 | CiaR | 2.79e-123 | two-component response regulator | 87.00 | 99.55 | AAK74935 |
| BPLBJJKO_1 | 1047981 | 1047277 | walR | 1.85e-121 | DNA-binding response regulator | 82.13 | 100.00 | ANC99504 |
| BPLBJJKO_1 | 768343 | 769014 | ciaR | 2.72e-121 | two component system response regulator | 84.82 | 99.12 | AIK75708 |
| BPLBJJKO_1 | 311628 | 312314 | CovR | 3.68e-118 | serves to repress GAS virulence factor-encoding genes | 81.22 | 100.00 | ACE75886 |
| BPLBJJKO_1 | 77025 | 77420 | SpxA2 | 3.71e-74 | transcriptional regulator | 90.91 | 100.00 | ERL21461 |
| BPLBJJKO_1 | 939464 | 939865 | SpxA1 | 3.76e-66 | transcriptional regulator | 80.60 | 100.00 | ERL19273 |
| BPLBJJKO_1 | 158683 | 159183 | RopE (M5005_Spy_1611) | 4.92e-75 | probable DNA-directed RNA polymerase subunit delta | 81.44 | 87.43 | AAK34603 |
| BPLBJJKO_1 | 1532822 | 1535119 | PFL (B9H01_RS01125) | 0.0 | formate C-acetyltransferase | 83.07 | 98.08 | MYN69560 |
| BPLBJJKO_1 | 1735647 | 1734628 | ilvC (SPD_0406) | 0.0 | ketol-acid reductoisomerase (NADP(+)) | 96.47 | 100.00 | ABJ55451 |
BLASTX v2.16.0 (Database: PHI base v4.16, May. 2024 release)
Plasmid
PlasmidFinder
| Query ID | Begin | End | Plasmid | Query / Template | Identity | Accession no. |
|---|---|---|---|---|---|---|
| BPLBJJKO_2 | 1 | 1050 | repUS31 | 1050 / 1050 | 100.00 | AY312234 |
PlasmidFinder v 2.1.6 (Database: plasmidfinder_db v 2.2.0 , Nov. 2024 release)
PlasmidHunter
| Query ID | Prediction | Chromosome | Plasmid |
|---|---|---|---|
| BPLBJJKO_1 | 0.0 | 1.0 | 0.0 |
| BPLBJJKO_2 | 1.0 | 0.0 | 1.0 |
PlasmidHunter v 1.4.5 (Database: May. 2024 release)
Prophage
Phigaro
| Query ID | Begin | End | Transposable | Taxonomy | pVOGs |
|---|---|---|---|---|---|
| No hit found | |||||
Phigaro v2.4.0 (Database: Jan. 2024 release)