Probiotic potential risk score
| ARGs | VFs | PGs | PPRS |
|---|---|---|---|
| 0 | 26 | 30 | 39.70 |
PPRS is classified as low-risk (≤4), medium-risk (4-6), and high-risk (≥6).
Antibiotic resistance genes
Comprehensive Antibiotic Resistance Database (CARD)
| Query ID | Begin | End | ARO name | ARO accession | CARD name | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
RGI v6.0.3 (Database: CARD Variants v4.0.2, Nov. 2023 release)
ResFinder
| Query ID | Begin | End | Resistance gene | Phenotype | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|
| No hit found | |||||||
ResFinder v4.6.0 (Database: resfinder_db, Aug. 2024 release)
AMRFinderPlus
| Query ID | Begin | End | Gene symbol | Sequence name | Method | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
AMRFinderPlus v4.0.3 (Database: Oct. 2024 release)
Virulence factors
Virulence Factor Database (VFDB)
| Query ID | qstart | qend | Gene name | e-value | VF name | VF category | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|---|
| FEJAADPC_1 | 43632 | 44471 | cbpD | 0.0 | Autolysin | Exoenzyme | 100.00 | 100.00 | WP_011226733 |
| FEJAADPC_1 | 1136187 | 1136780 | STR_RS05880 | 0.0 | Capsule | Immune modulation | 100.00 | 100.00 | WP_011226149 |
| FEJAADPC_1 | 1136187 | 1136780 | STER_RS06030 | 0.0 | Capsule | Immune modulation | 99.83 | 100.00 | WP_011226149 |
| FEJAADPC_1 | 1136187 | 1136780 | STU_RS15260 | 0.0 | Capsule | Immune modulation | 99.83 | 100.00 | WP_011226149 |
| FEJAADPC_1 | 1365678 | 1366634 | STU_RS16250 | 0.0 | Capsule | Immune modulation | 99.79 | 100.00 | WP_011226328 |
| FEJAADPC_1 | 1360824 | 1362608 | STU_RS16230 | 0.0 | Capsule | Immune modulation | 99.66 | 100.00 | WP_011226325 |
| FEJAADPC_1 | 1366631 | 1367779 | STU_RS16255 | 0.0 | Capsule | Immune modulation | 99.65 | 100.00 | WP_041828290 |
| FEJAADPC_1 | 1364885 | 1365694 | STU_RS16245 | 0.0 | Capsule | Immune modulation | 99.63 | 100.00 | WP_002948020 |
| FEJAADPC_1 | 1362605 | 1363660 | STU_RS16235 | 0.0 | Capsule | Immune modulation | 99.53 | 100.00 | WP_002948022 |
| FEJAADPC_1 | 1363680 | 1364885 | STU_RS16240 | 0.0 | Capsule | Immune modulation | 99.50 | 100.00 | WP_011226326 |
| FEJAADPC_1 | 900659 | 902317 | fbp54 | 0.0 | FBPs | Adherence | 99.46 | 100.00 | WP_011227179 |
| FEJAADPC_1 | 1136780 | 1137649 | rfbA | 0.0 | Capsule | Immune modulation | 99.42 | 100.00 | WP_011681286 |
| FEJAADPC_1 | 1371275 | 1372126 | rfbD | 0.0 | Capsule | Immune modulation | 99.41 | 100.00 | WP_014621820 |
| FEJAADPC_1 | 1367888 | 1368898 | STU_RS16260 | 0.0 | Capsule | Immune modulation | 99.11 | 100.00 | WP_011226330 |
| FEJAADPC_1 | 1024986 | 1025717 | STU_RS14645 | 0.0 | Capsule | Immune modulation | 98.91 | 100.00 | WP_011226048 |
| FEJAADPC_1 | 1171547 | 1172308 | srtA | 0.0 | Sortase A | Exoenzyme | 98.69 | 100.00 | - |
| FEJAADPC_1 | 1024986 | 1025717 | STER_RS05315 | 0.0 | Capsule | Immune modulation | 98.63 | 100.00 | WP_011681176 |
| FEJAADPC_1 | 1091363 | 1092152 | cshA | 0.0 | Cell surface hydrophobicity proteins | Adherence | 98.48 | 99.87 | - |
| FEJAADPC_1 | 1023535 | 1024275 | STER_RS05305 | 0.0 | Capsule | Immune modulation | 98.25 | 100.00 | WP_011681174 |
| FEJAADPC_1 | 1368898 | 1370172 | STU_RS16265 | 0.0 | Capsule | Immune modulation | 98.20 | 100.00 | WP_011226331 |
| FEJAADPC_1 | 1025718 | 1027172 | STU_RS14650 | 0.0 | Capsule | Immune modulation | 98.14 | 100.00 | WP_011226049 |
| FEJAADPC_1 | 1012400 | 1013854 | STR_RS05265 | 0.0 | Capsule | Immune modulation | 98.01 | 100.00 | WP_041827043 |
| FEJAADPC_1 | 1023535 | 1024275 | STU_RS14635 | 0.0 | Capsule | Immune modulation | 97.98 | 100.00 | WP_011226046 |
| FEJAADPC_1 | 1023540 | 1024275 | STR_RS05250 | 0.0 | Capsule | Immune modulation | 97.83 | 98.13 | WP_011227246 |
| FEJAADPC_1 | 1025718 | 1027172 | STER_RS05320 | 0.0 | Capsule | Immune modulation | 97.06 | 99.73 | WP_011681177 |
| FEJAADPC_1 | 1024285 | 1024977 | STR_RS05255 | 0.0 | Capsule | Immune modulation | 96.97 | 100.00 | WP_011227247 |
| FEJAADPC_1 | 1024285 | 1024977 | STU_RS14640 | 0.0 | Capsule | Immune modulation | 96.97 | 100.00 | WP_011226047 |
| FEJAADPC_1 | 626293 | 631188 | SAG_RS09105 | 0.0 | Agglutinin receptor | Adherence | 96.94 | 100.00 | WP_000167699 |
| FEJAADPC_1 | 626245 | 631188 | SSU98_0978 | 0.0 | Agglutinin receptor | Adherence | 95.77 | 99.82 | YP_001200536 |
| FEJAADPC_1 | 626245 | 631188 | SSU05_0965 | 0.0 | Agglutinin receptor | Adherence | 95.75 | 99.82 | YP_001198331 |
| FEJAADPC_1 | 1024285 | 1024977 | STER_RS05310 | 0.0 | Capsule | Immune modulation | 91.63 | 100.00 | WP_011681175 |
| FEJAADPC_1 | 591536 | 592839 | eno | 0.0 | Streptococcal enolase | Exoenzyme | 88.17 | 99.54 | WP_000022832 |
| FEJAADPC_1 | 1656539 | 1657549 | plr/gapA | 0.0 | Streptococcal plasmin receptor/GAPDH | Adherence | 86.82 | 99.51 | WP_002986042 |
| FEJAADPC_1 | 147791 | 149074 | tig/ropA | 0.0 | Trigger factor | Stress survival | 80.50 | 99.77 | WP_000107753 |
| FEJAADPC_1 | 1134712 | 1135758 | rfbB | 0.0 | Capsule | Immune modulation | 80.42 | 100.00 | WP_009659423 |
| FEJAADPC_1 | 1009433 | 1010016 | SPD_RS01775 | 1.10e-146 | Capsule | Immune modulation | 83.08 | 96.20 | WP_001819836 |
| FEJAADPC_1 | 1011935 | 1012399 | STR_RS05260 | 0.0 | Capsule | Immune modulation | 98.71 | 63.52 | WP_011227248 |
BLASTN v2.16.0 (Database: VFDB, Dec. 2024 release)
VirulenceFinder
| Query ID | Begin | End | Database | Virulence factor | Protein function | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
VirulenceFinder v2.0. 4 (Database: virulencefinder_db, Feb . 2024 release)
Pathogenic genes
PHI-base
| Query ID | qstart | qend | Gene name | e-value | Function | Identity | Coverage | Gene ID |
|---|---|---|---|---|---|---|---|---|
| FEJAADPC_1 | 626272 | 631185 | B9H01_RS04765 | 0.0 | glucan-binding protein | 96.34 | 99.70 | AUS90958 |
| FEJAADPC_1 | 1174995 | 1175978 | ldh(Sp_1220) | 0.0 | L-lactate dehydrogenase | 94.82 | 100.00 | AAK75326 |
| FEJAADPC_1 | 759509 | 760582 | MntE | 0.0 | manganese homeostasis | 94.41 | 99.72 | ABF32167 |
| FEJAADPC_1 | 1539773 | 1542076 | pfl2(Sp_0459) | 0.0 | formate acetyltransferase | 92.97 | 99.22 | AAK74619 |
| FEJAADPC_1 | 507899 | 508867 | spr0084 | 0.0 | pathogenitcity related | 92.88 | 98.48 | AAK98888 |
| FEJAADPC_1 | 780031 | 782277 | metE | 0.0 | methionine biosynthesis enzymes | 91.99 | 100.00 | AAK74738 |
| FEJAADPC_1 | 1268678 | 1270159 | SPD_0310 | 0.0 | UPF0371 protein SPD_0310 | 91.90 | 100.00 | ABJ54480 |
| FEJAADPC_1 | 63270 | 64268 | recA | 0.0 | DNA recombination and repair | 91.29 | 85.82 | AAL00560 |
| FEJAADPC_1 | 27150 | 28121 | prsA2 | 0.0 | ribose-phosphate pyrophosphokinase | 90.12 | 100.00 | ABF36968 |
| FEJAADPC_1 | 1423193 | 1422042 | potA | 0.0 | ABC transporter ATP-binding protein-spermidine/putrescine transport | 89.32 | 99.74 | AAL00050 |
| FEJAADPC_1 | 1387096 | 1385108 | uvrB | 0.0 | excinuclease ABC, B subunit | 88.99 | 100.00 | AE014259_2 |
| FEJAADPC_1 | 1158799 | 1157069 | ptsI | 0.0 | phosphoenolpyruvate-protein phosphotransferase | 87.69 | 100.00 | AAK34199 |
| FEJAADPC_1 | 1854484 | 1853006 | IMPDH | 0.0 | inosine-5'-monophosphate dehydrogenase | 87.63 | 100.00 | ADE32434 |
| FEJAADPC_1 | 591536 | 592837 | Eno | 0.0 | enolase | 86.21 | 99.77 | ABP90468 |
| FEJAADPC_1 | 1839288 | 1837396 | gidA | 0.0 | tRNA uridine 5-carboxymethylaminomethyl modification enzyme | 86.05 | 98.90 | ABP91129 |
| FEJAADPC_1 | 785203 | 783494 | PGM | 0.0 | phosphoglucomutase | 83.89 | 99.65 | ACH87041 |
| FEJAADPC_1 | 1698504 | 1699514 | pdh | 0.0 | pyruvate dehydrogenase | 83.09 | 99.70 | ABP91006 |
| FEJAADPC_1 | 926319 | 924967 | mnmE | 0.0 | central tRNA-modifying GTPase | 82.12 | 98.91 | ABP90420 |
| FEJAADPC_1 | 1748767 | 1746875 | PepO | 0.0 | endopeptidase | 80.03 | 100.00 | ABF32980 |
| FEJAADPC_1 | 577103 | 577993 | bglB | 1.34e-178 | putative phospho--glucosidase | 88.89 | 99.66 | AAK33487 |
| FEJAADPC_1 | 843122 | 842187 | SP_0676 | 7.44e-168 | transcription facot | 81.73 | 96.89 | AAK74821 |
| FEJAADPC_1 | 782469 | 783326 | metF | 1.51e-164 | methionine biosynthesis enzymes | 86.01 | 99.31 | AAK74739 |
| FEJAADPC_1 | 1063669 | 1062965 | covR | 1.07e-130 | responder protein | 85.11 | 100.00 | AAK71319 |
| FEJAADPC_1 | 1240625 | 1239954 | rr01 | 4.20e-125 | response regulator | 84.38 | 99.56 | CAB54566 |
| FEJAADPC_1 | 1063669 | 1062965 | walR | 5.38e-121 | DNA-binding response regulator | 81.28 | 100.00 | ANC99504 |
| FEJAADPC_1 | 789157 | 789825 | CiaR | 6.44e-120 | two-component response regulator | 85.65 | 99.55 | AAK74935 |
| FEJAADPC_1 | 789157 | 789828 | ciaR | 6.28e-118 | two component system response regulator | 83.48 | 99.12 | AIK75708 |
| FEJAADPC_1 | 296688 | 297374 | CovR | 1.01e-117 | serves to repress GAS virulence factor-encoding genes | 80.79 | 100.00 | ACE75886 |
| FEJAADPC_1 | 64544 | 64939 | SpxA2 | 3.73e-74 | transcriptional regulator | 90.91 | 100.00 | ERL21461 |
| FEJAADPC_1 | 937486 | 937887 | SpxA1 | 3.79e-66 | transcriptional regulator | 80.60 | 100.00 | ERL19273 |
| FEJAADPC_1 | 149232 | 149732 | RopE (M5005_Spy_1611) | 4.95e-75 | probable DNA-directed RNA polymerase subunit delta | 81.44 | 87.43 | AAK34603 |
| FEJAADPC_1 | 1539773 | 1542070 | PFL (B9H01_RS01125) | 0.0 | formate C-acetyltransferase | 82.94 | 98.08 | MYN69560 |
| FEJAADPC_1 | 1734366 | 1733347 | ilvC (SPD_0406) | 0.0 | ketol-acid reductoisomerase (NADP(+)) | 96.47 | 100.00 | ABJ55451 |
BLASTX v2.16.0 (Database: PHI base v4.16, May. 2024 release)
Plasmid
PlasmidFinder
| Query ID | Begin | End | Plasmid | Query / Template | Identity | Accession no. |
|---|---|---|---|---|---|---|
| No hit found | ||||||
PlasmidFinder v 2.1.6 (Database: plasmidfinder_db v 2.2.0 , Nov. 2024 release)
PlasmidHunter
| Query ID | Prediction | Chromosome | Plasmid |
|---|---|---|---|
| FEJAADPC_1 | 0.0 | 1.0 | 0.0 |
| FEJAADPC_2 | 0.0 | 1.0 | 0.0 |
PlasmidHunter v 1.4.5 (Database: May. 2024 release)
Prophage
Phigaro
| Query ID | Begin | End | Transposable | Taxonomy | pVOGs |
|---|---|---|---|---|---|
| FEJAADPC_1 | 648114 | 651003 | False | Unknown | VOG9403, VOG9404, VOG6396, VOG6396, VOG9405 |
Phigaro v2.4.0 (Database: Jan. 2024 release)