Probiotic potential risk score
| ARGs | VFs | PGs | PPRS |
|---|---|---|---|
| 0 | 27 | 32 | 41.87 |
PPRS is classified as low-risk (≤4), medium-risk (4-6), and high-risk (≥6).
Antibiotic resistance genes
Comprehensive Antibiotic Resistance Database (CARD)
| Query ID | Begin | End | ARO name | ARO accession | CARD name | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
RGI v6.0.3 (Database: CARD Variants v4.0.2, Nov. 2023 release)
ResFinder
| Query ID | Begin | End | Resistance gene | Phenotype | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|
| No hit found | |||||||
ResFinder v4.6.0 (Database: resfinder_db, Aug. 2024 release)
AMRFinderPlus
| Query ID | Begin | End | Gene symbol | Sequence name | Method | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
AMRFinderPlus v4.0.3 (Database: Oct. 2024 release)
Virulence factors
Virulence Factor Database (VFDB)
| Query ID | qstart | qend | Gene name | e-value | VF name | VF category | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|---|
| ONOMJNGG_48 | 60393 | 61262 | rfbA | 0.0 | Capsule | Immune modulation | 100.00 | 100.00 | WP_011681286 |
| ONOMJNGG_48 | 61262 | 61855 | STER_RS06030 | 0.0 | Capsule | Immune modulation | 100.00 | 100.00 | WP_011226149 |
| ONOMJNGG_23 | 1141 | 2284 | cshA | 0.0 | Cell surface hydrophobicity proteins | Adherence | 99.91 | 100.00 | - |
| ONOMJNGG_48 | 61262 | 61855 | STR_RS05880 | 0.0 | Capsule | Immune modulation | 99.83 | 100.00 | WP_011226149 |
| ONOMJNGG_45 | 81765 | 82214 | STU_RS14620 | 0.0 | Capsule | Immune modulation | 99.78 | 100.00 | WP_011226042 |
| ONOMJNGG_11 | 288325 | 289134 | STU_RS16245 | 0.0 | Capsule | Immune modulation | 99.75 | 100.00 | WP_002948020 |
| ONOMJNGG_48 | 61262 | 61855 | STU_RS15260 | 0.0 | Capsule | Immune modulation | 99.66 | 100.00 | WP_011226149 |
| ONOMJNGG_11 | 281893 | 282744 | rfbD | 0.0 | Capsule | Immune modulation | 99.65 | 100.00 | WP_014621820 |
| ONOMJNGG_33 | 96238 | 97896 | fbp54 | 0.0 | FBPs | Adherence | 99.64 | 100.00 | WP_011227179 |
| ONOMJNGG_11 | 291411 | 293195 | STU_RS16230 | 0.0 | Capsule | Immune modulation | 99.61 | 100.00 | WP_011226325 |
| ONOMJNGG_11 | 287385 | 288341 | STU_RS16250 | 0.0 | Capsule | Immune modulation | 99.58 | 100.00 | WP_011226328 |
| ONOMJNGG_11 | 285121 | 286131 | STU_RS16260 | 0.0 | Capsule | Immune modulation | 99.50 | 100.00 | WP_011226330 |
| ONOMJNGG_11 | 289134 | 290339 | STU_RS16240 | 0.0 | Capsule | Immune modulation | 99.09 | 100.00 | WP_011226326 |
| ONOMJNGG_11 | 290359 | 291414 | STU_RS16235 | 0.0 | Capsule | Immune modulation | 99.05 | 100.00 | WP_002948022 |
| ONOMJNGG_45 | 77654 | 78346 | STU_RS14640 | 0.0 | Capsule | Immune modulation | 98.99 | 100.00 | WP_011226047 |
| ONOMJNGG_11 | 286240 | 287388 | STU_RS16255 | 0.0 | Capsule | Immune modulation | 98.96 | 100.00 | WP_041828290 |
| ONOMJNGG_45 | 80762 | 81756 | STU_RS14625* | 0.0 | Capsule | Immune modulation | 98.70 | 99.90 | - |
| ONOMJNGG_45 | 77654 | 78346 | STR_RS05255 | 0.0 | Capsule | Immune modulation | 98.41 | 100.00 | WP_011227247 |
| ONOMJNGG_45 | 76914 | 77645 | STER_RS05315 | 0.0 | Capsule | Immune modulation | 97.68 | 100.00 | WP_011681176 |
| ONOMJNGG_45 | 76914 | 77645 | STU_RS14645 | 0.0 | Capsule | Immune modulation | 97.68 | 100.00 | WP_011226048 |
| ONOMJNGG_48 | 25731 | 26492 | srtA | 0.0 | Sortase A | Exoenzyme | 97.64 | 100.00 | - |
| ONOMJNGG_22 | 77462 | 78421 | cbpD | 0.0 | Autolysin | Exoenzyme | 97.63 | 99.90 | WP_082302295 |
| ONOMJNGG_45 | 75453 | 76913 | STER_RS05320 | 0.0 | Capsule | Immune modulation | 97.54 | 100.00 | WP_011681177 |
| ONOMJNGG_11 | 283847 | 285118 | STU_RS16265 | 0.0 | Capsule | Immune modulation | 97.48 | 99.76 | WP_011226331 |
| ONOMJNGG_45 | 78356 | 79096 | STER_RS05305 | 0.0 | Capsule | Immune modulation | 96.90 | 100.00 | WP_011681174 |
| ONOMJNGG_45 | 78356 | 79096 | STU_RS14635 | 0.0 | Capsule | Immune modulation | 96.76 | 100.00 | WP_011226046 |
| ONOMJNGG_45 | 75453 | 76913 | STU_RS14650 | 0.0 | Capsule | Immune modulation | 96.51 | 100.21 | WP_011226049 |
| ONOMJNGG_45 | 78356 | 79091 | STR_RS05250 | 0.0 | Capsule | Immune modulation | 95.92 | 98.13 | WP_011227246 |
| ONOMJNGG_45 | 75453 | 76913 | STR_RS05265 | 0.0 | Capsule | Immune modulation | 95.83 | 100.21 | WP_041827043 |
| ONOMJNGG_45 | 79153 | 80518 | STER_RS05300 | 0.0 | Capsule | Immune modulation | 94.14 | 99.85 | WP_011681173 |
| ONOMJNGG_45 | 79153 | 80520 | STU_RS14630 | 0.0 | Capsule | Immune modulation | 94.01 | 100.00 | WP_011226045 |
| ONOMJNGG_45 | 77654 | 78346 | STER_RS05310 | 0.0 | Capsule | Immune modulation | 90.33 | 100.00 | WP_011681175 |
| ONOMJNGG_14 | 3059 | 4362 | eno | 0.0 | Streptococcal enolase | Exoenzyme | 88.18 | 99.46 | WP_000022832 |
| ONOMJNGG_17 | 211 | 1221 | plr/gapA | 0.0 | Streptococcal plasmin receptor/GAPDH | Adherence | 86.54 | 99.41 | WP_002986042 |
| ONOMJNGG_2 | 5522 | 6805 | tig/ropA | 0.0 | Trigger factor | Stress survival | 80.73 | 99.77 | WP_000107753 |
| ONOMJNGG_48 | 62284 | 63330 | rfbB | 0.0 | Capsule | Immune modulation | 80.61 | 100.00 | WP_009659423 |
| ONOMJNGG_45 | 88919 | 89502 | SPD_RS01775 | 5.48e-143 | Capsule | Immune modulation | 82.56 | 96.20 | WP_001819836 |
| ONOMJNGG_45 | 86536 | 87000 | STR_RS05260 | 0.0 | Capsule | Immune modulation | 98.28 | 63.52 | WP_011227248 |
| ONOMJNGG_45 | 82214 | 82521 | STU_RS14615 | 2.51e-151 | Capsule | Immune modulation | 98.38 | 63.37 | WP_011226041 |
BLASTN v2.16.0 (Database: VFDB, Dec. 2024 release)
VirulenceFinder
| Query ID | Begin | End | Database | Virulence factor | Protein function | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
VirulenceFinder v2.0. 4 (Database: virulencefinder_db, Feb . 2024 release)
Pathogenic genes
PHI-base
| Query ID | qstart | qend | Gene name | e-value | Function | Identity | Coverage | Gene ID |
|---|---|---|---|---|---|---|---|---|
| ONOMJNGG_48 | 23044 | 22061 | ldh(Sp_1220) | 0.0 | L-lactate dehydrogenase | 94.82 | 100.00 | AAK75326 |
| ONOMJNGG_9 | 13831 | 12758 | MntE | 0.0 | manganese homeostasis | 94.41 | 99.72 | ABF32167 |
| ONOMJNGG_11 | 116470 | 114167 | pfl2(Sp_0459) | 0.0 | formate acetyltransferase | 93.10 | 99.22 | AAK74619 |
| ONOMJNGG_46 | 79486 | 78518 | spr0084 | 0.0 | pathogenitcity related | 92.88 | 98.48 | AAK98888 |
| ONOMJNGG_47 | 13376 | 11895 | SPD_0310 | 0.0 | UPF0371 protein SPD_0310 | 92.31 | 100.00 | ABJ54480 |
| ONOMJNGG_13 | 11393 | 9147 | metE | 0.0 | methionine biosynthesis enzymes | 91.99 | 100.00 | AAK74738 |
| ONOMJNGG_8 | 40529 | 41527 | recA | 0.0 | DNA recombination and repair | 91.29 | 85.82 | AAL00560 |
| ONOMJNGG_8 | 4414 | 5385 | prsA2 | 0.0 | ribose-phosphate pyrophosphokinase | 90.12 | 100.00 | ABF36968 |
| ONOMJNGG_11 | 230580 | 231731 | potA | 0.0 | ABC transporter ATP-binding protein-spermidine/putrescine transport | 89.32 | 99.74 | AAL00050 |
| ONOMJNGG_11 | 266926 | 268914 | uvrB | 0.0 | excinuclease ABC, B subunit | 88.84 | 100.00 | AE014259_2 |
| ONOMJNGG_48 | 39242 | 40972 | ptsI | 0.0 | phosphoenolpyruvate-protein phosphotransferase | 88.22 | 100.00 | AAK34199 |
| ONOMJNGG_1 | 13940 | 15418 | IMPDH | 0.0 | inosine-5'-monophosphate dehydrogenase | 87.63 | 100.00 | ADE32434 |
| ONOMJNGG_14 | 3059 | 4360 | Eno | 0.0 | enolase | 86.21 | 99.77 | ABP90468 |
| ONOMJNGG_1 | 28676 | 30568 | gidA | 0.0 | tRNA uridine 5-carboxymethylaminomethyl modification enzyme | 85.74 | 98.90 | ABP91129 |
| ONOMJNGG_13 | 6222 | 7931 | PGM | 0.0 | phosphoglucomutase | 84.06 | 99.65 | ACH87041 |
| ONOMJNGG_42 | 22718 | 23728 | pdh | 0.0 | pyruvate dehydrogenase | 83.09 | 99.70 | ABP91006 |
| ONOMJNGG_33 | 61442 | 62803 | mnmE | 0.0 | central tRNA-modifying GTPase | 82.24 | 99.56 | ABP90420 |
| ONOMJNGG_42 | 73060 | 71168 | PepO | 0.0 | endopeptidase | 80.19 | 100.00 | ABF32980 |
| ONOMJNGG_46 | 11638 | 10748 | bglB | 6.23e-180 | putative phospho--glucosidase | 88.89 | 99.66 | AAK33487 |
| ONOMJNGG_4 | 39728 | 40666 | SP_0676 | 6.52e-169 | transcription facot | 81.15 | 97.20 | AAK74821 |
| ONOMJNGG_13 | 8955 | 8098 | metF | 1.55e-166 | methionine biosynthesis enzymes | 86.36 | 99.31 | AAK74739 |
| ONOMJNGG_45 | 38635 | 39339 | covR | 2.16e-132 | responder protein | 85.53 | 100.00 | AAK71319 |
| ONOMJNGG_47 | 45520 | 46191 | rr01 | 1.20e-125 | response regulator | 83.93 | 99.56 | CAB54566 |
| ONOMJNGG_45 | 38635 | 39339 | walR | 9.12e-123 | DNA-binding response regulator | 82.13 | 100.00 | ANC99504 |
| ONOMJNGG_13 | 2267 | 1599 | CiaR | 2.07e-119 | two-component response regulator | 84.31 | 99.55 | AAK74935 |
| ONOMJNGG_44 | 7775 | 7089 | CovR | 5.41e-119 | serves to repress GAS virulence factor-encoding genes | 80.79 | 100.00 | ACE75886 |
| ONOMJNGG_13 | 2267 | 1596 | ciaR | 2.03e-117 | two component system response regulator | 82.14 | 99.12 | AIK75708 |
| ONOMJNGG_8 | 41803 | 42177 | SpxA2 | 2.63e-71 | transcriptional regulator | 91.20 | 94.70 | ERL21461 |
| ONOMJNGG_10 | 25621 | 25334 | spr0479 | 2.95e-49 | essential gene | 86.46 | 98.97 | AAK99283 |
| ONOMJNGG_22 | 119305 | 119559 | spr1327 | 1.86e-45 | essential gene | 95.29 | 100.00 | AAL00131 |
| ONOMJNGG_16 | 1288 | 1025 | spr0175 | 6.78e-43 | pathogenitcity related | 84.09 | 100.00 | AAK98979 |
| ONOMJNGG_16 | 461 | 195 | spr0177 | 1.48e-34 | essential gene | 84.27 | 88.12 | AAK98981 |
| ONOMJNGG_2 | 6963 | 7463 | RopE (M5005_Spy_1611) | 1.75e-76 | probable DNA-directed RNA polymerase subunit delta | 81.44 | 87.43 | AAK34603 |
| ONOMJNGG_11 | 116470 | 114173 | PFL (B9H01_RS01125) | 0.0 | formate C-acetyltransferase | 83.07 | 98.08 | MYN69560 |
| ONOMJNGG_42 | 58601 | 57582 | ilvC (SPD_0406) | 0.0 | ketol-acid reductoisomerase (NADP(+)) | 96.47 | 100.00 | ABJ55451 |
BLASTX v2.16.0 (Database: PHI base v4.16, May. 2024 release)
Plasmid
PlasmidFinder
| Query ID | Begin | End | Plasmid | Query / Template | Identity | Accession no. |
|---|---|---|---|---|---|---|
| No hit found | ||||||
PlasmidFinder v 2.1.6 (Database: plasmidfinder_db v 2.2.0 , Nov. 2024 release)
PlasmidHunter
| Query ID | Prediction | Chromosome | Plasmid |
|---|---|---|---|
| ONOMJNGG_1 | 0.0 | 1.0 | 0.0 |
| ONOMJNGG_2 | 0.0 | 1.0 | 0.0 |
| ONOMJNGG_3 | 0.0 | 1.0 | 0.0 |
| ONOMJNGG_4 | 0.0 | 1.0 | 0.0 |
| ONOMJNGG_5 | 0.0 | 1.0 | 0.0 |
| ONOMJNGG_6 | 0.0 | 1.0 | 0.0 |
| ONOMJNGG_7 | 0.0 | 1.0 | 0.0 |
| ONOMJNGG_8 | 0.0 | 1.0 | 0.0 |
| ONOMJNGG_9 | 0.0 | 1.0 | 0.0 |
| ONOMJNGG_10 | 0.0 | 1.0 | 0.0 |
| ONOMJNGG_11 | 0.0 | 1.0 | 0.0 |
| ONOMJNGG_12 | 0.0 | 1.0 | 0.0 |
| ONOMJNGG_13 | 0.0 | 1.0 | 0.0 |
| ONOMJNGG_14 | 0.0 | 1.0 | 0.0 |
| ONOMJNGG_15 | 0.0 | 1.0 | 0.0 |
| ONOMJNGG_16 | 0.0 | 1.0 | 0.0 |
| ONOMJNGG_17 | 0.0 | 1.0 | 0.0 |
| ONOMJNGG_18 | 0.0 | 1.0 | 0.0 |
| ONOMJNGG_19 | 0.0 | 1.0 | 0.0 |
| ONOMJNGG_20 | 0.0 | 1.0 | 0.0 |
| ONOMJNGG_21 | 0.0 | 1.0 | 0.0 |
| ONOMJNGG_22 | 0.0 | 1.0 | 0.0 |
| ONOMJNGG_23 | 0.0 | 1.0 | 0.0 |
| ONOMJNGG_24 | 1.0 | 0.0 | 1.0 |
| ONOMJNGG_26 | 0.0 | 1.0 | 0.0 |
| ONOMJNGG_27 | 1.0 | 0.0 | 1.0 |
| ONOMJNGG_28 | 0.0 | 1.0 | 0.0 |
| ONOMJNGG_29 | 0.0 | 1.0 | 0.0 |
| ONOMJNGG_30 | 0.0 | 1.0 | 0.0 |
| ONOMJNGG_31 | 0.0 | 1.0 | 0.0 |
| ONOMJNGG_32 | 0.0 | 1.0 | 0.0 |
| ONOMJNGG_33 | 0.0 | 1.0 | 0.0 |
| ONOMJNGG_34 | 0.0 | 1.0 | 0.0 |
| ONOMJNGG_35 | 0.0 | 1.0 | 0.0 |
| ONOMJNGG_36 | 0.0 | 1.0 | 0.0 |
| ONOMJNGG_42 | 0.0 | 1.0 | 0.0 |
| ONOMJNGG_44 | 0.0 | 1.0 | 0.0 |
| ONOMJNGG_45 | 0.0 | 1.0 | 0.0 |
| ONOMJNGG_46 | 0.0 | 1.0 | 0.0 |
| ONOMJNGG_47 | 0.0 | 1.0 | 0.0 |
| ONOMJNGG_48 | 0.0 | 1.0 | 0.0 |
PlasmidHunter v 1.4.5 (Database: May. 2024 release)
Prophage
Phigaro
| Query ID | Begin | End | Transposable | Taxonomy | pVOGs |
|---|---|---|---|---|---|
| No hit found | |||||
Phigaro v2.4.0 (Database: Jan. 2024 release)