Probiotic potential risk score
| ARGs | VFs | PGs | PPRS |
|---|---|---|---|
| 0 | 25 | 28 | 37.54 |
PPRS is classified as low-risk (≤4), medium-risk (4-6), and high-risk (≥6).
Antibiotic resistance genes
Comprehensive Antibiotic Resistance Database (CARD)
| Query ID | Begin | End | ARO name | ARO accession | CARD name | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
RGI v6.0.3 (Database: CARD Variants v4.0.2, Nov. 2023 release)
ResFinder
| Query ID | Begin | End | Resistance gene | Phenotype | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|
| No hit found | |||||||
ResFinder v4.6.0 (Database: resfinder_db, Aug. 2024 release)
AMRFinderPlus
| Query ID | Begin | End | Gene symbol | Sequence name | Method | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
AMRFinderPlus v4.0.3 (Database: Oct. 2024 release)
Virulence factors
Virulence Factor Database (VFDB)
| Query ID | qstart | qend | Gene name | e-value | VF name | VF category | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|---|
| MJCNFBFF_1 | 45029 | 45868 | cbpD | 0.0 | Autolysin | Exoenzyme | 100.00 | 100.00 | WP_011226733 |
| MJCNFBFF_1 | 1112286 | 1112879 | STER_RS06030 | 0.0 | Capsule | Immune modulation | 100.00 | 100.00 | WP_011226149 |
| MJCNFBFF_1 | 1112879 | 1113748 | rfbA | 0.0 | Capsule | Immune modulation | 99.89 | 100.00 | WP_011681286 |
| MJCNFBFF_1 | 1112286 | 1112879 | STR_RS05880 | 0.0 | Capsule | Immune modulation | 99.83 | 100.00 | WP_011226149 |
| MJCNFBFF_1 | 1327224 | 1328033 | STU_RS16245 | 0.0 | Capsule | Immune modulation | 99.75 | 100.00 | WP_002948020 |
| MJCNFBFF_1 | 1326019 | 1327224 | STU_RS16240 | 0.0 | Capsule | Immune modulation | 99.67 | 100.00 | WP_011226326 |
| MJCNFBFF_1 | 1112286 | 1112879 | STU_RS15260 | 0.0 | Capsule | Immune modulation | 99.66 | 100.00 | WP_011226149 |
| MJCNFBFF_1 | 1328017 | 1328973 | STU_RS16250 | 0.0 | Capsule | Immune modulation | 99.58 | 100.00 | WP_011226328 |
| MJCNFBFF_1 | 1323163 | 1324947 | STU_RS16230 | 0.0 | Capsule | Immune modulation | 99.50 | 100.00 | WP_011226325 |
| MJCNFBFF_1 | 1324944 | 1325999 | STU_RS16235 | 0.0 | Capsule | Immune modulation | 99.43 | 100.00 | WP_002948022 |
| MJCNFBFF_1 | 874453 | 876111 | fbp54 | 0.0 | FBPs | Adherence | 99.34 | 100.00 | WP_011227179 |
| MJCNFBFF_1 | 987964 | 988695 | STER_RS05315 | 0.0 | Capsule | Immune modulation | 99.04 | 100.00 | WP_011681176 |
| MJCNFBFF_1 | 987964 | 988695 | STU_RS14645 | 0.0 | Capsule | Immune modulation | 98.77 | 100.00 | WP_011226048 |
| MJCNFBFF_1 | 1331814 | 1332776 | STU_RS16260 | 0.0 | Capsule | Immune modulation | 98.65 | 95.25 | WP_011226330 |
| MJCNFBFF_1 | 987964 | 988695 | STR_RS05260 | 0.0 | Capsule | Immune modulation | 98.63 | 100.00 | WP_011227248 |
| MJCNFBFF_1 | 1328970 | 1330118 | STU_RS16255 | 0.0 | Capsule | Immune modulation | 98.43 | 100.00 | WP_041828290 |
| MJCNFBFF_1 | 1055956 | 1056744 | cshA | 0.0 | Cell surface hydrophobicity proteins | Adherence | 98.36 | 99.75 | - |
| MJCNFBFF_1 | 978023 | 979438 | STER_RS05250 | 0.0 | Capsule | Immune modulation | 97.81 | 100.00 | WP_011681165 |
| MJCNFBFF_1 | 1149073 | 1149834 | srtA | 0.0 | Sortase A | Exoenzyme | 97.64 | 100.00 | - |
| MJCNFBFF_1 | 1332779 | 1334050 | STU_RS16265 | 0.0 | Capsule | Immune modulation | 97.64 | 99.76 | WP_011226331 |
| MJCNFBFF_1 | 988696 | 990156 | STER_RS05320 | 0.0 | Capsule | Immune modulation | 97.47 | 100.00 | WP_011681177 |
| MJCNFBFF_1 | 1335153 | 1336004 | rfbD | 0.0 | Capsule | Immune modulation | 97.42 | 100.00 | WP_014621820 |
| MJCNFBFF_1 | 988696 | 990156 | STU_RS14650 | 0.0 | Capsule | Immune modulation | 96.85 | 100.21 | WP_011226049 |
| MJCNFBFF_1 | 988696 | 990156 | STR_RS05265 | 0.0 | Capsule | Immune modulation | 95.89 | 100.21 | WP_041827043 |
| MJCNFBFF_1 | 985073 | 986438 | STER_RS05300 | 0.0 | Capsule | Immune modulation | 95.17 | 99.85 | WP_011681173 |
| MJCNFBFF_1 | 987263 | 987955 | STR_RS05255 | 0.0 | Capsule | Immune modulation | 95.11 | 99.86 | WP_011227247 |
| MJCNFBFF_1 | 987263 | 987955 | STU_RS14640 | 0.0 | Capsule | Immune modulation | 95.11 | 99.86 | WP_011226047 |
| MJCNFBFF_1 | 985071 | 986438 | STU_RS14630 | 0.0 | Capsule | Immune modulation | 93.93 | 100.00 | WP_011226045 |
| MJCNFBFF_1 | 986495 | 987253 | STER_RS05305 | 0.0 | Capsule | Immune modulation | 93.54 | 100.94 | WP_011681174 |
| MJCNFBFF_1 | 986495 | 987253 | STU_RS14635 | 0.0 | Capsule | Immune modulation | 93.41 | 100.94 | WP_011226046 |
| MJCNFBFF_1 | 986500 | 987253 | STR_RS05250 | 0.0 | Capsule | Immune modulation | 93.10 | 99.07 | WP_011227246 |
| MJCNFBFF_1 | 987263 | 987955 | STER_RS05310 | 0.0 | Capsule | Immune modulation | 89.18 | 100.00 | WP_011681175 |
| MJCNFBFF_1 | 613117 | 614420 | eno | 0.0 | Streptococcal enolase | Exoenzyme | 88.18 | 99.46 | WP_000022832 |
| MJCNFBFF_1 | 1630883 | 1631893 | plr/gapA | 0.0 | Streptococcal plasmin receptor/GAPDH | Adherence | 87.45 | 99.90 | WP_002986042 |
| MJCNFBFF_1 | 148848 | 150131 | tig/ropA | 0.0 | Trigger factor | Stress survival | 80.73 | 99.77 | WP_000107753 |
| MJCNFBFF_1 | 1110811 | 1111857 | rfbB | 0.0 | Capsule | Immune modulation | 80.61 | 100.00 | WP_009659423 |
BLASTN v2.16.0 (Database: VFDB, Dec. 2024 release)
VirulenceFinder
| Query ID | Begin | End | Database | Virulence factor | Protein function | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
VirulenceFinder v2.0. 4 (Database: virulencefinder_db, Feb . 2024 release)
Pathogenic genes
PHI-base
| Query ID | qstart | qend | Gene name | e-value | Function | Identity | Coverage | Gene ID |
|---|---|---|---|---|---|---|---|---|
| MJCNFBFF_1 | 717922 | 718995 | MntE | 0.0 | manganese homeostasis | 94.97 | 99.72 | ABF32167 |
| MJCNFBFF_1 | 1152521 | 1153504 | ldh(Sp_1220) | 0.0 | L-lactate dehydrogenase | 94.82 | 100.00 | AAK75326 |
| MJCNFBFF_1 | 529414 | 530382 | spr0084 | 0.0 | pathogenitcity related | 93.19 | 98.48 | AAK98888 |
| MJCNFBFF_1 | 1506499 | 1508802 | pfl2(Sp_0459) | 0.0 | formate acetyltransferase | 92.97 | 99.22 | AAK74619 |
| MJCNFBFF_1 | 1227886 | 1229367 | SPD_0310 | 0.0 | UPF0371 protein SPD_0310 | 92.31 | 100.00 | ABJ54480 |
| MJCNFBFF_1 | 740658 | 742904 | metE | 0.0 | methionine biosynthesis enzymes | 91.99 | 100.00 | AAK74738 |
| MJCNFBFF_1 | 64659 | 65651 | recA | 0.0 | DNA recombination and repair | 91.24 | 85.31 | AAL00560 |
| MJCNFBFF_1 | 28545 | 29516 | prsA2 | 0.0 | ribose-phosphate pyrophosphokinase | 90.12 | 100.00 | ABF36968 |
| MJCNFBFF_1 | 1389581 | 1388430 | potA | 0.0 | ABC transporter ATP-binding protein-spermidine/putrescine transport | 89.32 | 99.74 | AAL00050 |
| MJCNFBFF_1 | 1350992 | 1349004 | uvrB | 0.0 | excinuclease ABC, B subunit | 88.99 | 100.00 | AE014259_2 |
| MJCNFBFF_1 | 1136323 | 1134593 | ptsI | 0.0 | phosphoenolpyruvate-protein phosphotransferase | 88.04 | 100.00 | AAK34199 |
| MJCNFBFF_1 | 1840066 | 1838588 | IMPDH | 0.0 | inosine-5'-monophosphate dehydrogenase | 87.42 | 100.00 | ADE32434 |
| MJCNFBFF_1 | 613117 | 614418 | Eno | 0.0 | enolase | 86.21 | 99.77 | ABP90468 |
| MJCNFBFF_1 | 1824876 | 1822984 | gidA | 0.0 | tRNA uridine 5-carboxymethylaminomethyl modification enzyme | 86.05 | 98.90 | ABP91129 |
| MJCNFBFF_1 | 745829 | 744120 | PGM | 0.0 | phosphoglucomutase | 83.89 | 99.65 | ACH87041 |
| MJCNFBFF_1 | 1672855 | 1673865 | pdh | 0.0 | pyruvate dehydrogenase | 83.09 | 99.70 | ABP91006 |
| MJCNFBFF_1 | 898168 | 896807 | mnmE | 0.0 | central tRNA-modifying GTPase | 82.24 | 99.56 | ABP90420 |
| MJCNFBFF_1 | 1726021 | 1724129 | PepO | 0.0 | endopeptidase | 80.03 | 100.00 | ABF32980 |
| MJCNFBFF_1 | 598682 | 599572 | bglB | 1.33e-178 | putative phospho--glucosidase | 88.89 | 99.66 | AAK33487 |
| MJCNFBFF_1 | 813642 | 812704 | SP_0676 | 2.36e-167 | transcription facot | 81.15 | 97.20 | AAK74821 |
| MJCNFBFF_1 | 743096 | 743953 | metF | 8.64e-165 | methionine biosynthesis enzymes | 86.36 | 99.31 | AAK74739 |
| MJCNFBFF_1 | 1026852 | 1026148 | covR | 4.38e-131 | responder protein | 85.53 | 100.00 | AAK71319 |
| MJCNFBFF_1 | 1208912 | 1208241 | rr01 | 4.14e-126 | response regulator | 84.82 | 99.56 | CAB54566 |
| MJCNFBFF_1 | 1026852 | 1026148 | walR | 1.84e-121 | DNA-binding response regulator | 82.13 | 100.00 | ANC99504 |
| MJCNFBFF_1 | 306681 | 307367 | CovR | 1.01e-117 | serves to repress GAS virulence factor-encoding genes | 80.79 | 100.00 | ACE75886 |
| MJCNFBFF_1 | 749783 | 750451 | CiaR | 2.02e-117 | two-component response regulator | 84.31 | 99.55 | AAK74935 |
| MJCNFBFF_1 | 749783 | 750454 | ciaR | 1.99e-115 | two component system response regulator | 82.14 | 99.12 | AIK75708 |
| MJCNFBFF_1 | 65963 | 66358 | SpxA2 | 3.70e-74 | transcriptional regulator | 90.91 | 100.00 | ERL21461 |
| MJCNFBFF_1 | 150289 | 150789 | RopE (M5005_Spy_1611) | 4.92e-75 | probable DNA-directed RNA polymerase subunit delta | 81.44 | 87.43 | AAK34603 |
| MJCNFBFF_1 | 1506499 | 1508796 | PFL (B9H01_RS01125) | 0.0 | formate C-acetyltransferase | 82.94 | 98.08 | MYN69560 |
| MJCNFBFF_1 | 1711564 | 1710545 | ilvC (SPD_0406) | 0.0 | ketol-acid reductoisomerase (NADP(+)) | 95.88 | 100.00 | ABJ55451 |
BLASTX v2.16.0 (Database: PHI base v4.16, May. 2024 release)
Plasmid
PlasmidFinder
| Query ID | Begin | End | Plasmid | Query / Template | Identity | Accession no. |
|---|---|---|---|---|---|---|
| No hit found | ||||||
PlasmidFinder v 2.1.6 (Database: plasmidfinder_db v 2.2.0 , Nov. 2024 release)
PlasmidHunter
| Query ID | Prediction | Chromosome | Plasmid |
|---|---|---|---|
| MJCNFBFF_1 | 0.0 | 1.0 | 0.0 |
PlasmidHunter v 1.4.5 (Database: May. 2024 release)
Prophage
Phigaro
| Query ID | Begin | End | Transposable | Taxonomy | pVOGs |
|---|---|---|---|---|---|
| No hit found | |||||
Phigaro v2.4.0 (Database: Jan. 2024 release)