Probiotic potential risk score
| ARGs | VFs | PGs | PPRS |
|---|---|---|---|
| 0 | 25 | 29 | 38.29 |
PPRS is classified as low-risk (≤4), medium-risk (4-6), and high-risk (≥6).
Antibiotic resistance genes
Comprehensive Antibiotic Resistance Database (CARD)
| Query ID | Begin | End | ARO name | ARO accession | CARD name | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
RGI v6.0.3 (Database: CARD Variants v4.0.2, Nov. 2023 release)
ResFinder
| Query ID | Begin | End | Resistance gene | Phenotype | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|
| No hit found | |||||||
ResFinder v4.6.0 (Database: resfinder_db, Aug. 2024 release)
AMRFinderPlus
| Query ID | Begin | End | Gene symbol | Sequence name | Method | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
AMRFinderPlus v4.0.3 (Database: Oct. 2024 release)
Virulence factors
Virulence Factor Database (VFDB)
| Query ID | qstart | qend | Gene name | e-value | VF name | VF category | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|---|
| OKAKFCAE_1 | 1125195 | 1126064 | rfbA | 0.0 | Capsule | Immune modulation | 100.00 | 100.00 | WP_011681286 |
| OKAKFCAE_1 | 1124602 | 1125195 | STER_RS06030 | 0.0 | Capsule | Immune modulation | 100.00 | 100.00 | WP_011226149 |
| OKAKFCAE_1 | 1124602 | 1125195 | STR_RS05880 | 0.0 | Capsule | Immune modulation | 99.83 | 100.00 | WP_011226149 |
| OKAKFCAE_1 | 1340152 | 1341108 | STU_RS16250 | 0.0 | Capsule | Immune modulation | 99.79 | 100.00 | WP_011226328 |
| OKAKFCAE_1 | 1339359 | 1340168 | STU_RS16245 | 0.0 | Capsule | Immune modulation | 99.75 | 100.00 | WP_002948020 |
| OKAKFCAE_1 | 1341105 | 1342253 | STU_RS16255 | 0.0 | Capsule | Immune modulation | 99.74 | 100.00 | WP_041828290 |
| OKAKFCAE_1 | 1124602 | 1125195 | STU_RS15260 | 0.0 | Capsule | Immune modulation | 99.66 | 100.00 | WP_011226149 |
| OKAKFCAE_1 | 1338154 | 1339359 | STU_RS16240 | 0.0 | Capsule | Immune modulation | 99.58 | 100.00 | WP_011226326 |
| OKAKFCAE_1 | 1335298 | 1337082 | STU_RS16230 | 0.0 | Capsule | Immune modulation | 99.55 | 100.00 | WP_011226325 |
| OKAKFCAE_1 | 1345749 | 1346600 | rfbD | 0.0 | Capsule | Immune modulation | 99.53 | 100.00 | WP_014621820 |
| OKAKFCAE_1 | 43685 | 44524 | cbpD | 0.0 | Autolysin | Exoenzyme | 99.52 | 100.00 | WP_011226733 |
| OKAKFCAE_1 | 1342362 | 1343372 | STU_RS16260 | 0.0 | Capsule | Immune modulation | 99.50 | 100.00 | WP_011226330 |
| OKAKFCAE_1 | 1337079 | 1338134 | STU_RS16235 | 0.0 | Capsule | Immune modulation | 99.43 | 100.00 | WP_002948022 |
| OKAKFCAE_1 | 889517 | 891175 | fbp54 | 0.0 | FBPs | Adherence | 99.34 | 100.00 | WP_011227179 |
| OKAKFCAE_1 | 1001651 | 1002382 | STER_RS05315 | 0.0 | Capsule | Immune modulation | 99.04 | 100.00 | WP_011681176 |
| OKAKFCAE_1 | 1001651 | 1002382 | STU_RS14645 | 0.0 | Capsule | Immune modulation | 98.77 | 100.00 | WP_011226048 |
| OKAKFCAE_1 | 1001651 | 1002382 | STR_RS05260 | 0.0 | Capsule | Immune modulation | 98.63 | 100.00 | WP_011227248 |
| OKAKFCAE_1 | 1068385 | 1069173 | cshA | 0.0 | Cell surface hydrophobicity proteins | Adherence | 98.36 | 99.75 | - |
| OKAKFCAE_1 | 991710 | 993125 | STER_RS05250 | 0.0 | Capsule | Immune modulation | 97.81 | 100.00 | WP_011681165 |
| OKAKFCAE_1 | 1161387 | 1162148 | srtA | 0.0 | Sortase A | Exoenzyme | 97.64 | 100.00 | - |
| OKAKFCAE_1 | 1343375 | 1344646 | STU_RS16265 | 0.0 | Capsule | Immune modulation | 97.48 | 99.76 | WP_011226331 |
| OKAKFCAE_1 | 1002383 | 1003843 | STER_RS05320 | 0.0 | Capsule | Immune modulation | 97.47 | 100.00 | WP_011681177 |
| OKAKFCAE_1 | 1002383 | 1003843 | STU_RS14650 | 0.0 | Capsule | Immune modulation | 96.85 | 100.21 | WP_011226049 |
| OKAKFCAE_1 | 1002383 | 1003843 | STR_RS05265 | 0.0 | Capsule | Immune modulation | 95.89 | 100.21 | WP_041827043 |
| OKAKFCAE_1 | 1000950 | 1001642 | STR_RS05255 | 0.0 | Capsule | Immune modulation | 95.40 | 99.86 | WP_011227247 |
| OKAKFCAE_1 | 1000950 | 1001642 | STU_RS14640 | 0.0 | Capsule | Immune modulation | 95.40 | 99.86 | WP_011226047 |
| OKAKFCAE_1 | 998760 | 1000125 | STER_RS05300 | 0.0 | Capsule | Immune modulation | 95.17 | 99.85 | WP_011681173 |
| OKAKFCAE_1 | 1000182 | 1000940 | STER_RS05305 | 0.0 | Capsule | Immune modulation | 93.94 | 100.94 | WP_011681174 |
| OKAKFCAE_1 | 998758 | 1000125 | STU_RS14630 | 0.0 | Capsule | Immune modulation | 93.93 | 100.00 | WP_011226045 |
| OKAKFCAE_1 | 1000182 | 1000940 | STU_RS14635 | 0.0 | Capsule | Immune modulation | 93.81 | 100.94 | WP_011226046 |
| OKAKFCAE_1 | 1000187 | 1000940 | STR_RS05250 | 0.0 | Capsule | Immune modulation | 93.24 | 99.07 | WP_011227246 |
| OKAKFCAE_1 | 1000950 | 1001642 | STER_RS05310 | 0.0 | Capsule | Immune modulation | 89.47 | 100.00 | WP_011681175 |
| OKAKFCAE_1 | 622167 | 623470 | eno | 0.0 | Streptococcal enolase | Exoenzyme | 88.10 | 99.46 | WP_000022832 |
| OKAKFCAE_1 | 1637383 | 1638393 | plr/gapA | 0.0 | Streptococcal plasmin receptor/GAPDH | Adherence | 87.45 | 99.90 | WP_002986042 |
| OKAKFCAE_1 | 160733 | 162016 | tig/ropA | 0.0 | Trigger factor | Stress survival | 80.65 | 99.77 | WP_000107753 |
| OKAKFCAE_1 | 1123127 | 1124173 | rfbB | 0.0 | Capsule | Immune modulation | 80.61 | 100.00 | WP_009659423 |
BLASTN v2.16.0 (Database: VFDB, Dec. 2024 release)
VirulenceFinder
| Query ID | Begin | End | Database | Virulence factor | Protein function | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
VirulenceFinder v2.0. 4 (Database: virulencefinder_db, Feb . 2024 release)
Pathogenic genes
PHI-base
| Query ID | qstart | qend | Gene name | e-value | Function | Identity | Coverage | Gene ID |
|---|---|---|---|---|---|---|---|---|
| OKAKFCAE_1 | 1164835 | 1165818 | ldh(Sp_1220) | 0.0 | L-lactate dehydrogenase | 94.82 | 100.00 | AAK75326 |
| OKAKFCAE_1 | 729838 | 730911 | MntE | 0.0 | manganese homeostasis | 94.41 | 99.72 | ABF32167 |
| OKAKFCAE_1 | 537446 | 538414 | spr0084 | 0.0 | pathogenitcity related | 93.19 | 98.48 | AAK98888 |
| OKAKFCAE_1 | 1514374 | 1516677 | pfl2(Sp_0459) | 0.0 | formate acetyltransferase | 92.97 | 99.22 | AAK74619 |
| OKAKFCAE_1 | 1240198 | 1241679 | SPD_0310 | 0.0 | UPF0371 protein SPD_0310 | 92.31 | 100.00 | ABJ54480 |
| OKAKFCAE_1 | 766305 | 768551 | metE | 0.0 | methionine biosynthesis enzymes | 91.99 | 100.00 | AAK74738 |
| OKAKFCAE_1 | 65873 | 66865 | recA | 0.0 | DNA recombination and repair | 91.24 | 85.31 | AAL00560 |
| OKAKFCAE_1 | 27201 | 28172 | prsA2 | 0.0 | ribose-phosphate pyrophosphokinase | 90.12 | 100.00 | ABF36968 |
| OKAKFCAE_1 | 1398903 | 1397752 | potA | 0.0 | ABC transporter ATP-binding protein-spermidine/putrescine transport | 89.32 | 99.74 | AAL00050 |
| OKAKFCAE_1 | 1361891 | 1359903 | uvrB | 0.0 | excinuclease ABC, B subunit | 88.99 | 100.00 | AE014259_2 |
| OKAKFCAE_1 | 1148639 | 1146909 | ptsI | 0.0 | phosphoenolpyruvate-protein phosphotransferase | 88.04 | 100.00 | AAK34199 |
| OKAKFCAE_1 | 1856326 | 1854848 | IMPDH | 0.0 | inosine-5'-monophosphate dehydrogenase | 87.42 | 100.00 | ADE32434 |
| OKAKFCAE_1 | 622167 | 623468 | Eno | 0.0 | enolase | 86.21 | 99.77 | ABP90468 |
| OKAKFCAE_1 | 1841137 | 1839245 | gidA | 0.0 | tRNA uridine 5-carboxymethylaminomethyl modification enzyme | 86.05 | 98.90 | ABP91129 |
| OKAKFCAE_1 | 771476 | 769767 | PGM | 0.0 | phosphoglucomutase | 83.89 | 99.65 | ACH87041 |
| OKAKFCAE_1 | 1681064 | 1682074 | pdh | 0.0 | pyruvate dehydrogenase | 83.09 | 99.70 | ABP91006 |
| OKAKFCAE_1 | 915396 | 914035 | mnmE | 0.0 | central tRNA-modifying GTPase | 82.24 | 99.56 | ABP90420 |
| OKAKFCAE_1 | 1732758 | 1730866 | PepO | 0.0 | endopeptidase | 80.03 | 100.00 | ABF32980 |
| OKAKFCAE_1 | 607732 | 608622 | bglB | 5.34e-177 | putative phospho--glucosidase | 88.22 | 99.66 | AAK33487 |
| OKAKFCAE_1 | 830842 | 829904 | SP_0676 | 2.37e-167 | transcription facot | 81.15 | 97.20 | AAK74821 |
| OKAKFCAE_1 | 768743 | 769600 | metF | 8.71e-165 | methionine biosynthesis enzymes | 86.36 | 99.31 | AAK74739 |
| OKAKFCAE_1 | 1040551 | 1039847 | covR | 4.41e-131 | responder protein | 85.53 | 100.00 | AAK71319 |
| OKAKFCAE_1 | 1221222 | 1220551 | rr01 | 3.03e-124 | response regulator | 83.93 | 99.56 | CAB54566 |
| OKAKFCAE_1 | 1040551 | 1039847 | walR | 1.86e-121 | DNA-binding response regulator | 82.13 | 100.00 | ANC99504 |
| OKAKFCAE_1 | 775430 | 776098 | CiaR | 9.48e-118 | two-component response regulator | 84.75 | 99.55 | AAK74935 |
| OKAKFCAE_1 | 315220 | 315906 | CovR | 1.01e-117 | serves to repress GAS virulence factor-encoding genes | 80.79 | 100.00 | ACE75886 |
| OKAKFCAE_1 | 775430 | 776101 | ciaR | 1.03e-115 | two component system response regulator | 82.59 | 99.12 | AIK75708 |
| OKAKFCAE_1 | 67177 | 67572 | SpxA2 | 3.21e-73 | transcriptional regulator | 90.15 | 100.00 | ERL21461 |
| OKAKFCAE_1 | 926754 | 927155 | SpxA1 | 3.79e-66 | transcriptional regulator | 80.60 | 100.00 | ERL19273 |
| OKAKFCAE_1 | 162174 | 162674 | RopE (M5005_Spy_1611) | 4.96e-75 | probable DNA-directed RNA polymerase subunit delta | 81.44 | 87.43 | AAK34603 |
| OKAKFCAE_1 | 1514374 | 1516671 | PFL (B9H01_RS01125) | 0.0 | formate C-acetyltransferase | 82.94 | 98.08 | MYN69560 |
| OKAKFCAE_1 | 1718349 | 1717330 | ilvC (SPD_0406) | 0.0 | ketol-acid reductoisomerase (NADP(+)) | 95.88 | 100.00 | ABJ55451 |
BLASTX v2.16.0 (Database: PHI base v4.16, May. 2024 release)
Plasmid
PlasmidFinder
| Query ID | Begin | End | Plasmid | Query / Template | Identity | Accession no. |
|---|---|---|---|---|---|---|
| No hit found | ||||||
PlasmidFinder v 2.1.6 (Database: plasmidfinder_db v 2.2.0 , Nov. 2024 release)
PlasmidHunter
| Query ID | Prediction | Chromosome | Plasmid |
|---|---|---|---|
| OKAKFCAE_1 | 0.0 | 1.0 | 0.0 |
PlasmidHunter v 1.4.5 (Database: May. 2024 release)
Prophage
Phigaro
| Query ID | Begin | End | Transposable | Taxonomy | pVOGs |
|---|---|---|---|---|---|
| No hit found | |||||
Phigaro v2.4.0 (Database: Jan. 2024 release)