Probiotic potential risk score
| ARGs | VFs | PGs | PPRS |
|---|---|---|---|
| 0 | 23 | 27 | 35.47 |
PPRS is classified as low-risk (≤4), medium-risk (4-6), and high-risk (≥6).
Antibiotic resistance genes
Comprehensive Antibiotic Resistance Database (CARD)
| Query ID | Begin | End | ARO name | ARO accession | CARD name | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
RGI v6.0.3 (Database: CARD Variants v4.0.2, Nov. 2023 release)
ResFinder
| Query ID | Begin | End | Resistance gene | Phenotype | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|
| No hit found | |||||||
ResFinder v4.6.0 (Database: resfinder_db, Aug. 2024 release)
AMRFinderPlus
| Query ID | Begin | End | Gene symbol | Sequence name | Method | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
AMRFinderPlus v4.0.3 (Database: Oct. 2024 release)
Virulence factors
Virulence Factor Database (VFDB)
| Query ID | qstart | qend | Gene name | e-value | VF name | VF category | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|---|
| KIAAFJHI_1 | 1301407 | 1302216 | STU_RS16245 | 0.0 | Capsule | Immune modulation | 99.88 | 100.00 | WP_002948020 |
| KIAAFJHI_1 | 1302200 | 1303156 | STU_RS16250 | 0.0 | Capsule | Immune modulation | 99.69 | 100.00 | WP_011226328 |
| KIAAFJHI_1 | 859300 | 860958 | fbp54 | 0.0 | FBPs | Adherence | 99.58 | 100.00 | WP_011227179 |
| KIAAFJHI_1 | 1300202 | 1301407 | STU_RS16240 | 0.0 | Capsule | Immune modulation | 99.58 | 100.00 | WP_011226326 |
| KIAAFJHI_1 | 43611 | 44450 | cbpD | 0.0 | Autolysin | Exoenzyme | 99.52 | 100.00 | WP_011226733 |
| KIAAFJHI_1 | 1086795 | 1087664 | rfbA | 0.0 | Capsule | Immune modulation | 99.42 | 100.00 | WP_011681286 |
| KIAAFJHI_1 | 1086202 | 1086795 | STR_RS05880 | 0.0 | Capsule | Immune modulation | 99.33 | 100.00 | WP_011226149 |
| KIAAFJHI_1 | 1041375 | 1042165 | cshA | 0.0 | Cell surface hydrophobicity proteins | Adherence | 99.24 | 100.00 | - |
| KIAAFJHI_1 | 1299127 | 1300182 | STU_RS16235 | 0.0 | Capsule | Immune modulation | 99.24 | 100.00 | WP_002948022 |
| KIAAFJHI_1 | 1086202 | 1086795 | STER_RS06030 | 0.0 | Capsule | Immune modulation | 99.16 | 100.00 | WP_011226149 |
| KIAAFJHI_1 | 1086202 | 1086795 | STU_RS15260 | 0.0 | Capsule | Immune modulation | 99.16 | 100.00 | WP_011226149 |
| KIAAFJHI_1 | 1297348 | 1299130 | STU_RS16230 | 0.0 | Capsule | Immune modulation | 99.16 | 99.89 | WP_011226325 |
| KIAAFJHI_1 | 1303153 | 1304301 | STU_RS16255 | 0.0 | Capsule | Immune modulation | 99.13 | 100.00 | WP_041828290 |
| KIAAFJHI_1 | 1305731 | 1306582 | rfbD | 0.0 | Capsule | Immune modulation | 99.06 | 100.00 | WP_014621820 |
| KIAAFJHI_1 | 974695 | 975426 | STER_RS05315 | 0.0 | Capsule | Immune modulation | 98.91 | 100.00 | WP_011681176 |
| KIAAFJHI_1 | 1121583 | 1122344 | srtA | 0.0 | Sortase A | Exoenzyme | 98.82 | 100.00 | - |
| KIAAFJHI_1 | 964707 | 966122 | STER_RS05250 | 0.0 | Capsule | Immune modulation | 98.80 | 100.00 | WP_011681165 |
| KIAAFJHI_1 | 974695 | 975426 | STU_RS14645 | 0.0 | Capsule | Immune modulation | 98.63 | 100.00 | WP_011226048 |
| KIAAFJHI_1 | 974695 | 975426 | STR_RS05260 | 0.0 | Capsule | Immune modulation | 98.50 | 100.00 | WP_011227248 |
| KIAAFJHI_1 | 973994 | 974686 | STR_RS05255 | 0.0 | Capsule | Immune modulation | 97.83 | 100.00 | WP_011227247 |
| KIAAFJHI_1 | 973994 | 974686 | STU_RS14640 | 0.0 | Capsule | Immune modulation | 97.83 | 100.00 | WP_011226047 |
| KIAAFJHI_1 | 975427 | 976887 | STER_RS05320 | 0.0 | Capsule | Immune modulation | 97.60 | 100.00 | WP_011681177 |
| KIAAFJHI_1 | 973246 | 973984 | STER_RS05305 | 0.0 | Capsule | Immune modulation | 97.56 | 99.73 | WP_011681174 |
| KIAAFJHI_1 | 975427 | 976887 | STU_RS14650 | 0.0 | Capsule | Immune modulation | 96.99 | 100.21 | WP_011226049 |
| KIAAFJHI_1 | 973246 | 973984 | STU_RS14635 | 0.0 | Capsule | Immune modulation | 96.89 | 99.73 | WP_011226046 |
| KIAAFJHI_1 | 973249 | 973984 | STR_RS05250 | 0.0 | Capsule | Immune modulation | 96.74 | 98.13 | WP_011227246 |
| KIAAFJHI_1 | 975427 | 976887 | STR_RS05265 | 0.0 | Capsule | Immune modulation | 96.03 | 100.21 | WP_041827043 |
| KIAAFJHI_1 | 971819 | 973186 | STU_RS14630 | 0.0 | Capsule | Immune modulation | 94.96 | 100.00 | WP_011226045 |
| KIAAFJHI_1 | 971821 | 973186 | STER_RS05300 | 0.0 | Capsule | Immune modulation | 94.36 | 99.85 | WP_011681173 |
| KIAAFJHI_1 | 973994 | 974686 | STER_RS05310 | 0.0 | Capsule | Immune modulation | 90.04 | 100.00 | WP_011681175 |
| KIAAFJHI_1 | 611334 | 612637 | eno | 0.0 | Streptococcal enolase | Exoenzyme | 88.09 | 99.54 | WP_000022832 |
| KIAAFJHI_1 | 1585738 | 1586748 | plr/gapA | 0.0 | Streptococcal plasmin receptor/GAPDH | Adherence | 86.82 | 99.51 | WP_002986042 |
| KIAAFJHI_1 | 1084726 | 1085772 | rfbB | 0.0 | Capsule | Immune modulation | 80.61 | 100.00 | WP_009659423 |
| KIAAFJHI_1 | 148417 | 149700 | tig/ropA | 0.0 | Trigger factor | Stress survival | 80.26 | 99.77 | WP_000107753 |
BLASTN v2.16.0 (Database: VFDB, Dec. 2024 release)
VirulenceFinder
| Query ID | Begin | End | Database | Virulence factor | Protein function | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
VirulenceFinder v2.0. 4 (Database: virulencefinder_db, Feb . 2024 release)
Pathogenic genes
PHI-base
| Query ID | qstart | qend | Gene name | e-value | Function | Identity | Coverage | Gene ID |
|---|---|---|---|---|---|---|---|---|
| KIAAFJHI_1 | 1125031 | 1126014 | ldh(Sp_1220) | 0.0 | L-lactate dehydrogenase | 94.82 | 100.00 | AAK75326 |
| KIAAFJHI_1 | 720055 | 721128 | MntE | 0.0 | manganese homeostasis | 94.41 | 99.72 | ABF32167 |
| KIAAFJHI_1 | 529307 | 530275 | spr0084 | 0.0 | pathogenitcity related | 93.19 | 98.48 | AAK98888 |
| KIAAFJHI_1 | 1464615 | 1466918 | pfl2(Sp_0459) | 0.0 | formate acetyltransferase | 92.84 | 99.22 | AAK74619 |
| KIAAFJHI_1 | 740577 | 742823 | metE | 0.0 | methionine biosynthesis enzymes | 91.99 | 100.00 | AAK74738 |
| KIAAFJHI_1 | 1209609 | 1211090 | SPD_0310 | 0.0 | UPF0371 protein SPD_0310 | 91.90 | 100.00 | ABJ54480 |
| KIAAFJHI_1 | 65476 | 66474 | recA | 0.0 | DNA recombination and repair | 91.29 | 85.82 | AAL00560 |
| KIAAFJHI_1 | 27131 | 28102 | prsA2 | 0.0 | ribose-phosphate pyrophosphokinase | 90.12 | 100.00 | ABF36968 |
| KIAAFJHI_1 | 1349244 | 1348093 | potA | 0.0 | ABC transporter ATP-binding protein-spermidine/putrescine transport | 89.32 | 99.74 | AAL00050 |
| KIAAFJHI_1 | 1321236 | 1319248 | uvrB | 0.0 | excinuclease ABC, B subunit | 88.99 | 100.00 | AE014259_2 |
| KIAAFJHI_1 | 1108835 | 1107105 | ptsI | 0.0 | phosphoenolpyruvate-protein phosphotransferase | 87.69 | 100.00 | AAK34199 |
| KIAAFJHI_1 | 1785770 | 1784292 | IMPDH | 0.0 | inosine-5'-monophosphate dehydrogenase | 87.63 | 100.00 | ADE32434 |
| KIAAFJHI_1 | 1771036 | 1769144 | gidA | 0.0 | tRNA uridine 5-carboxymethylaminomethyl modification enzyme | 86.05 | 98.90 | ABP91129 |
| KIAAFJHI_1 | 611334 | 612635 | Eno | 0.0 | enolase | 85.98 | 99.77 | ABP90468 |
| KIAAFJHI_1 | 745748 | 744039 | PGM | 0.0 | phosphoglucomutase | 83.89 | 99.65 | ACH87041 |
| KIAAFJHI_1 | 1627696 | 1628706 | pdh | 0.0 | pyruvate dehydrogenase | 83.09 | 99.70 | ABP91006 |
| KIAAFJHI_1 | 884845 | 883484 | mnmE | 0.0 | central tRNA-modifying GTPase | 82.24 | 99.56 | ABP90420 |
| KIAAFJHI_1 | 596907 | 597797 | bglB | 1.29e-177 | putative phospho--glucosidase | 88.55 | 99.66 | AAK33487 |
| KIAAFJHI_1 | 803756 | 802821 | SP_0676 | 7.16e-168 | transcription facot | 81.73 | 96.89 | AAK74821 |
| KIAAFJHI_1 | 743015 | 743872 | metF | 4.51e-164 | methionine biosynthesis enzymes | 86.01 | 99.31 | AAK74739 |
| KIAAFJHI_1 | 1013688 | 1012984 | covR | 4.25e-131 | responder protein | 85.53 | 100.00 | AAK71319 |
| KIAAFJHI_1 | 1181493 | 1180822 | rr01 | 3.86e-125 | response regulator | 84.38 | 99.56 | CAB54566 |
| KIAAFJHI_1 | 1013688 | 1012984 | walR | 1.79e-121 | DNA-binding response regulator | 82.13 | 100.00 | ANC99504 |
| KIAAFJHI_1 | 749702 | 750370 | CiaR | 9.12e-118 | two-component response regulator | 84.75 | 99.55 | AAK74935 |
| KIAAFJHI_1 | 313221 | 313907 | CovR | 9.76e-118 | serves to repress GAS virulence factor-encoding genes | 80.79 | 100.00 | ACE75886 |
| KIAAFJHI_1 | 749702 | 750373 | ciaR | 9.89e-116 | two component system response regulator | 82.59 | 99.12 | AIK75708 |
| KIAAFJHI_1 | 66750 | 67124 | SpxA2 | 1.12e-69 | transcriptional regulator | 91.20 | 94.70 | ERL21461 |
| KIAAFJHI_1 | 149858 | 150358 | RopE (M5005_Spy_1611) | 9.58e-75 | probable DNA-directed RNA polymerase subunit delta | 80.84 | 87.43 | AAK34603 |
| KIAAFJHI_1 | 1464615 | 1466912 | PFL (B9H01_RS01125) | 0.0 | formate C-acetyltransferase | 82.81 | 98.08 | MYN69560 |
| KIAAFJHI_1 | 1663559 | 1662540 | ilvC (SPD_0406) | 0.0 | ketol-acid reductoisomerase (NADP(+)) | 96.18 | 100.00 | ABJ55451 |
BLASTX v2.16.0 (Database: PHI base v4.16, May. 2024 release)
Plasmid
PlasmidFinder
| Query ID | Begin | End | Plasmid | Query / Template | Identity | Accession no. |
|---|---|---|---|---|---|---|
| No hit found | ||||||
PlasmidFinder v 2.1.6 (Database: plasmidfinder_db v 2.2.0 , Nov. 2024 release)
PlasmidHunter
| Query ID | Prediction | Chromosome | Plasmid |
|---|---|---|---|
| KIAAFJHI_1 | 0.0 | 1.0 | 0.0 |
PlasmidHunter v 1.4.5 (Database: May. 2024 release)
Prophage
Phigaro
| Query ID | Begin | End | Transposable | Taxonomy | pVOGs |
|---|---|---|---|---|---|
| No hit found | |||||
Phigaro v2.4.0 (Database: Jan. 2024 release)