Probiotic potential risk score
| ARGs | VFs | PGs | PPRS |
|---|---|---|---|
| 0 | 28 | 28 | 39.60 |
PPRS is classified as low-risk (≤4), medium-risk (4-6), and high-risk (≥6).
Antibiotic resistance genes
Comprehensive Antibiotic Resistance Database (CARD)
| Query ID | Begin | End | ARO name | ARO accession | CARD name | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
RGI v6.0.3 (Database: CARD Variants v4.0.2, Nov. 2023 release)
ResFinder
| Query ID | Begin | End | Resistance gene | Phenotype | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|
| No hit found | |||||||
ResFinder v4.6.0 (Database: resfinder_db, Aug. 2024 release)
AMRFinderPlus
| Query ID | Begin | End | Gene symbol | Sequence name | Method | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
AMRFinderPlus v4.0.3 (Database: Oct. 2024 release)
Virulence factors
Virulence Factor Database (VFDB)
| Query ID | qstart | qend | Gene name | e-value | VF name | VF category | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|---|
| AKLKEDEL_1 | 1157351 | 1158220 | rfbA | 0.0 | Capsule | Immune modulation | 100.00 | 100.00 | WP_011681286 |
| AKLKEDEL_1 | 1156758 | 1157351 | STER_RS06030 | 0.0 | Capsule | Immune modulation | 100.00 | 100.00 | WP_011226149 |
| AKLKEDEL_1 | 1370411 | 1371217 | STER_RS07060 | 0.0 | Capsule | Immune modulation | 100.00 | 100.00 | WP_011681437 |
| AKLKEDEL_1 | 1378439 | 1379698 | STER_RS07100 | 0.0 | Capsule | Immune modulation | 100.00 | 100.00 | WP_011681445 |
| AKLKEDEL_1 | 1372155 | 1373303 | STER_RS07070 | 0.0 | Capsule | Immune modulation | 99.91 | 100.00 | WP_011681439 |
| AKLKEDEL_1 | 1156758 | 1157351 | STR_RS05880 | 0.0 | Capsule | Immune modulation | 99.83 | 100.00 | WP_011226149 |
| AKLKEDEL_1 | 1371217 | 1372158 | STR_RS06905 | 0.0 | Capsule | Immune modulation | 99.68 | 100.00 | WP_011227430 |
| AKLKEDEL_1 | 1156758 | 1157351 | STU_RS15260 | 0.0 | Capsule | Immune modulation | 99.66 | 100.00 | WP_011226149 |
| AKLKEDEL_1 | 1366037 | 1367782 | STER_RS07045 | 0.0 | Capsule | Immune modulation | 99.60 | 100.00 | WP_011681434 |
| AKLKEDEL_1 | 1377466 | 1378442 | STER_RS07095 | 0.0 | Capsule | Immune modulation | 99.59 | 99.90 | WP_011681444 |
| AKLKEDEL_1 | 921771 | 923429 | fbp54 | 0.0 | FBPs | Adherence | 99.58 | 100.00 | WP_011227179 |
| AKLKEDEL_1 | 1371217 | 1372158 | STER_RS07065 | 0.0 | Capsule | Immune modulation | 99.58 | 100.00 | WP_011681438 |
| AKLKEDEL_1 | 43637 | 44476 | cbpD | 0.0 | Autolysin | Exoenzyme | 99.52 | 100.00 | WP_011226733 |
| AKLKEDEL_1 | 1370411 | 1371217 | STR_RS06900 | 0.0 | Capsule | Immune modulation | 99.50 | 100.00 | WP_011227429 |
| AKLKEDEL_1 | 1372155 | 1373303 | STR_RS06910 | 0.0 | Capsule | Immune modulation | 99.30 | 100.00 | WP_011227431 |
| AKLKEDEL_1 | 1376480 | 1377448 | STER_RS07090 | 0.0 | Capsule | Immune modulation | 99.28 | 100.00 | WP_011681443 |
| AKLKEDEL_1 | 1193544 | 1194305 | srtA | 0.0 | Sortase A | Exoenzyme | 99.08 | 100.00 | - |
| AKLKEDEL_1 | 1029981 | 1030712 | STER_RS05315 | 0.0 | Capsule | Immune modulation | 98.50 | 100.00 | WP_011681176 |
| AKLKEDEL_1 | 1099104 | 1099897 | cshA | 0.0 | Cell surface hydrophobicity proteins | Adherence | 98.36 | 100.25 | - |
| AKLKEDEL_1 | 1030713 | 1032167 | STR_RS05265 | 0.0 | Capsule | Immune modulation | 98.35 | 100.00 | WP_041827043 |
| AKLKEDEL_1 | 1375763 | 1376478 | STER_RS07085 | 0.0 | Capsule | Immune modulation | 98.32 | 99.86 | WP_011681442 |
| AKLKEDEL_1 | 1018553 | 1019968 | STER_RS05250 | 0.0 | Capsule | Immune modulation | 98.31 | 100.00 | WP_011681165 |
| AKLKEDEL_1 | 1029981 | 1030712 | STU_RS14645 | 0.0 | Capsule | Immune modulation | 98.22 | 100.00 | WP_011226048 |
| AKLKEDEL_1 | 1374641 | 1375417 | STER_RS07075 | 0.0 | Capsule | Immune modulation | 98.20 | 100.00 | WP_011681440 |
| AKLKEDEL_1 | 1029981 | 1030712 | STR_RS05260 | 0.0 | Capsule | Immune modulation | 98.09 | 100.00 | WP_011227248 |
| AKLKEDEL_1 | 1030713 | 1032167 | STU_RS14650 | 0.0 | Capsule | Immune modulation | 98.01 | 100.00 | WP_011226049 |
| AKLKEDEL_1 | 1366037 | 1367782 | STR_RS06885 | 0.0 | Capsule | Immune modulation | 97.94 | 100.00 | WP_011227426 |
| AKLKEDEL_1 | 1028530 | 1029270 | STU_RS14635 | 0.0 | Capsule | Immune modulation | 97.84 | 100.00 | WP_011226046 |
| AKLKEDEL_1 | 1028530 | 1029270 | STER_RS05305 | 0.0 | Capsule | Immune modulation | 97.71 | 100.00 | WP_011681174 |
| AKLKEDEL_1 | 1029280 | 1029972 | STR_RS05255 | 0.0 | Capsule | Immune modulation | 97.69 | 100.00 | WP_011227247 |
| AKLKEDEL_1 | 1029280 | 1029972 | STU_RS14640 | 0.0 | Capsule | Immune modulation | 97.69 | 100.00 | WP_011226047 |
| AKLKEDEL_1 | 1379817 | 1380668 | rfbD | 0.0 | Capsule | Immune modulation | 97.42 | 100.00 | WP_014621820 |
| AKLKEDEL_1 | 1028535 | 1029270 | STR_RS05250 | 0.0 | Capsule | Immune modulation | 97.42 | 98.13 | WP_011227246 |
| AKLKEDEL_1 | 1030713 | 1032167 | STER_RS05320 | 0.0 | Capsule | Immune modulation | 97.12 | 99.79 | WP_011681177 |
| AKLKEDEL_1 | 1027106 | 1028473 | STU_RS14630 | 0.0 | Capsule | Immune modulation | 95.25 | 100.00 | WP_011226045 |
| AKLKEDEL_1 | 1027108 | 1028473 | STER_RS05300 | 0.0 | Capsule | Immune modulation | 93.27 | 99.85 | WP_011681173 |
| AKLKEDEL_1 | 1029280 | 1029972 | STER_RS05310 | 0.0 | Capsule | Immune modulation | 91.05 | 100.00 | WP_011681175 |
| AKLKEDEL_1 | 614097 | 615400 | eno | 0.0 | Streptococcal enolase | Exoenzyme | 88.10 | 99.46 | WP_000022832 |
| AKLKEDEL_1 | 1671914 | 1672924 | plr/gapA | 0.0 | Streptococcal plasmin receptor/GAPDH | Adherence | 86.54 | 99.41 | WP_002986042 |
| AKLKEDEL_1 | 1369188 | 1370411 | SGO_RS05025 | 0.0 | Capsule | Immune modulation | 84.52 | 99.92 | WP_012000441 |
| AKLKEDEL_1 | 1370411 | 1371217 | SGO_RS05020 | 0.0 | Capsule | Immune modulation | 82.90 | 100.00 | WP_012000440 |
| AKLKEDEL_1 | 144599 | 145882 | tig/ropA | 0.0 | Trigger factor | Stress survival | 80.73 | 99.77 | WP_000107753 |
| AKLKEDEL_1 | 1155283 | 1156329 | rfbB | 0.0 | Capsule | Immune modulation | 80.61 | 100.00 | WP_009659423 |
| AKLKEDEL_1 | 1016185 | 1016771 | SPD_RS01775 | 1.12e-141 | Capsule | Immune modulation | 82.48 | 96.70 | WP_001819836 |
| AKLKEDEL_1 | 1369674 | 1370411 | STER_RS07055 | 0.0 | Capsule | Immune modulation | 98.10 | 61.35 | WP_011681436 |
| AKLKEDEL_1 | 1369674 | 1370411 | STR_RS06895 | 0.0 | Capsule | Immune modulation | 97.83 | 61.35 | WP_011227428 |
BLASTN v2.16.0 (Database: VFDB, Dec. 2024 release)
VirulenceFinder
| Query ID | Begin | End | Database | Virulence factor | Protein function | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
VirulenceFinder v2.0. 4 (Database: virulencefinder_db, Feb . 2024 release)
Pathogenic genes
PHI-base
| Query ID | qstart | qend | Gene name | e-value | Function | Identity | Coverage | Gene ID |
|---|---|---|---|---|---|---|---|---|
| AKLKEDEL_1 | 765819 | 766892 | MntE | 0.0 | manganese homeostasis | 94.97 | 99.72 | ABF32167 |
| AKLKEDEL_1 | 1196992 | 1197975 | ldh(Sp_1220) | 0.0 | L-lactate dehydrogenase | 94.82 | 100.00 | AAK75326 |
| AKLKEDEL_1 | 1547374 | 1549677 | pfl2(Sp_0459) | 0.0 | formate acetyltransferase | 92.97 | 99.22 | AAK74619 |
| AKLKEDEL_1 | 530408 | 531376 | spr0084 | 0.0 | pathogenitcity related | 92.88 | 98.48 | AAK98888 |
| AKLKEDEL_1 | 1266026 | 1267507 | SPD_0310 | 0.0 | UPF0371 protein SPD_0310 | 92.31 | 100.00 | ABJ54480 |
| AKLKEDEL_1 | 800318 | 802564 | metE | 0.0 | methionine biosynthesis enzymes | 91.86 | 100.00 | AAK74738 |
| AKLKEDEL_1 | 64418 | 65416 | recA | 0.0 | DNA recombination and repair | 91.29 | 85.82 | AAL00560 |
| AKLKEDEL_1 | 27154 | 28125 | prsA2 | 0.0 | ribose-phosphate pyrophosphokinase | 90.12 | 100.00 | ABF36968 |
| AKLKEDEL_1 | 1432349 | 1431198 | potA | 0.0 | ABC transporter ATP-binding protein-spermidine/putrescine transport | 89.32 | 99.74 | AAL00050 |
| AKLKEDEL_1 | 1393706 | 1391718 | uvrB | 0.0 | excinuclease ABC, B subunit | 88.69 | 100.00 | AE014259_2 |
| AKLKEDEL_1 | 1180794 | 1179064 | ptsI | 0.0 | phosphoenolpyruvate-protein phosphotransferase | 88.04 | 100.00 | AAK34199 |
| AKLKEDEL_1 | 1866591 | 1865113 | IMPDH | 0.0 | inosine-5'-monophosphate dehydrogenase | 87.42 | 100.00 | ADE32434 |
| AKLKEDEL_1 | 614097 | 615398 | Eno | 0.0 | enolase | 86.21 | 99.77 | ABP90468 |
| AKLKEDEL_1 | 1851403 | 1849511 | gidA | 0.0 | tRNA uridine 5-carboxymethylaminomethyl modification enzyme | 86.05 | 98.90 | ABP91129 |
| AKLKEDEL_1 | 805489 | 803780 | PGM | 0.0 | phosphoglucomutase | 83.89 | 99.65 | ACH87041 |
| AKLKEDEL_1 | 1713881 | 1714891 | pdh | 0.0 | pyruvate dehydrogenase | 83.09 | 99.70 | ABP91006 |
| AKLKEDEL_1 | 949897 | 948536 | mnmE | 0.0 | central tRNA-modifying GTPase | 81.58 | 99.56 | ABP90420 |
| AKLKEDEL_1 | 1764216 | 1762324 | PepO | 0.0 | endopeptidase | 80.03 | 100.00 | ABF32980 |
| AKLKEDEL_1 | 599662 | 600552 | bglB | 1.35e-178 | putative phospho--glucosidase | 88.89 | 99.66 | AAK33487 |
| AKLKEDEL_1 | 863496 | 862558 | SP_0676 | 2.39e-167 | transcription facot | 81.15 | 97.20 | AAK74821 |
| AKLKEDEL_1 | 802756 | 803613 | metF | 9.03e-166 | methionine biosynthesis enzymes | 86.71 | 99.31 | AAK74739 |
| AKLKEDEL_1 | 1069014 | 1068310 | covR | 4.44e-131 | responder protein | 85.53 | 100.00 | AAK71319 |
| AKLKEDEL_1 | 1247050 | 1246379 | rr01 | 3.04e-124 | response regulator | 83.93 | 99.56 | CAB54566 |
| AKLKEDEL_1 | 1069014 | 1068310 | walR | 1.87e-121 | DNA-binding response regulator | 82.13 | 100.00 | ANC99504 |
| AKLKEDEL_1 | 303622 | 304308 | CovR | 1.02e-117 | serves to repress GAS virulence factor-encoding genes | 80.79 | 100.00 | ACE75886 |
| AKLKEDEL_1 | 809443 | 810111 | CiaR | 2.05e-117 | two-component response regulator | 84.31 | 99.55 | AAK74935 |
| AKLKEDEL_1 | 809443 | 810114 | ciaR | 2.01e-115 | two component system response regulator | 82.14 | 99.12 | AIK75708 |
| AKLKEDEL_1 | 65692 | 66066 | SpxA2 | 1.17e-69 | transcriptional regulator | 91.20 | 94.70 | ERL21461 |
| AKLKEDEL_1 | 146040 | 146540 | RopE (M5005_Spy_1611) | 4.99e-75 | probable DNA-directed RNA polymerase subunit delta | 81.44 | 87.43 | AAK34603 |
| AKLKEDEL_1 | 1547374 | 1549671 | PFL (B9H01_RS01125) | 0.0 | formate C-acetyltransferase | 82.94 | 98.08 | MYN69560 |
| AKLKEDEL_1 | 1749765 | 1748746 | ilvC (SPD_0406) | 0.0 | ketol-acid reductoisomerase (NADP(+)) | 96.47 | 100.00 | ABJ55451 |
BLASTX v2.16.0 (Database: PHI base v4.16, May. 2024 release)
Plasmid
PlasmidFinder
| Query ID | Begin | End | Plasmid | Query / Template | Identity | Accession no. |
|---|---|---|---|---|---|---|
| No hit found | ||||||
PlasmidFinder v 2.1.6 (Database: plasmidfinder_db v 2.2.0 , Nov. 2024 release)
PlasmidHunter
| Query ID | Prediction | Chromosome | Plasmid |
|---|---|---|---|
| AKLKEDEL_1 | 0.0 | 1.0 | 0.0 |
PlasmidHunter v 1.4.5 (Database: May. 2024 release)
Prophage
Phigaro
| Query ID | Begin | End | Transposable | Taxonomy | pVOGs |
|---|---|---|---|---|---|
| AKLKEDEL_1 | 615459 | 657022 | False | Siphoviridae | VOG0275, VOG7656, VOG4602, VOG6127, VOG3622, VOG1564, VOG9469, VOG3478, VOG0651, VOG4566, VOG0189, VOG3430, VOG0283, VOG0685, VOG0226, VOG10904, VOG4693, VOG0655, VOG3468, VOG0656, VOG4571, VOG0152, VOG9667, VOG0657, VOG0658, VOG0198, VOG4694, VOG4052, VOG3300, VOG3299, VOG0796, VOG4544, VOG0720, VOG4564, VOG3434, VOG1887, VOG3435, VOG4713, VOG0723, VOG5660, VOG0724, VOG0799, VOG0725, VOG0800, VOG3636, VOG4605, VOG4599, VOG0647, VOG4782, VOG3298, VOG0641, VOG0054 |
Phigaro v2.4.0 (Database: Jan. 2024 release)