Probiotic potential risk score
| ARGs | VFs | PGs | PPRS |
|---|---|---|---|
| 0 | 24 | 32 | 40.00 |
PPRS is classified as low-risk (≤4), medium-risk (4-6), and high-risk (≥6).
Antibiotic resistance genes
Comprehensive Antibiotic Resistance Database (CARD)
| Query ID | Begin | End | ARO name | ARO accession | CARD name | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
RGI v6.0.3 (Database: CARD Variants v4.0.2, Nov. 2023 release)
ResFinder
| Query ID | Begin | End | Resistance gene | Phenotype | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|
| No hit found | |||||||
ResFinder v4.6.0 (Database: resfinder_db, Aug. 2024 release)
AMRFinderPlus
| Query ID | Begin | End | Gene symbol | Sequence name | Method | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
AMRFinderPlus v4.0.3 (Database: Oct. 2024 release)
Virulence factors
Virulence Factor Database (VFDB)
| Query ID | qstart | qend | Gene name | e-value | VF name | VF category | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|---|
| CIJKMGPI_1 | 189018 | 190277 | STER_RS07100 | 0.0 | Capsule | Immune modulation | 99.76 | 100.00 | WP_011681445 |
| CIJKMGPI_1 | 191269 | 192237 | STER_RS07090 | 0.0 | Capsule | Immune modulation | 99.48 | 100.00 | WP_011681443 |
| CIJKMGPI_23 | 175534 | 176403 | rfbA | 0.0 | Capsule | Immune modulation | 99.42 | 100.00 | WP_011681286 |
| CIJKMGPI_1 | 190274 | 191251 | STER_RS07095 | 0.0 | Capsule | Immune modulation | 99.39 | 100.00 | WP_011681444 |
| CIJKMGPI_53 | 63119 | 64777 | fbp54 | 0.0 | FBPs | Adherence | 99.34 | 100.00 | WP_011227179 |
| CIJKMGPI_23 | 176403 | 176996 | STR_RS05880 | 0.0 | Capsule | Immune modulation | 99.33 | 100.00 | WP_011226149 |
| CIJKMGPI_23 | 176403 | 176996 | STER_RS06030 | 0.0 | Capsule | Immune modulation | 99.16 | 100.00 | WP_011226149 |
| CIJKMGPI_23 | 176403 | 176996 | STU_RS15260 | 0.0 | Capsule | Immune modulation | 99.16 | 100.00 | WP_011226149 |
| CIJKMGPI_23 | 140875 | 141636 | srtA | 0.0 | Sortase A | Exoenzyme | 99.08 | 100.00 | - |
| CIJKMGPI_50 | 14062 | 14793 | STER_RS05315 | 0.0 | Capsule | Immune modulation | 98.63 | 100.00 | WP_011681176 |
| CIJKMGPI_50 | 14062 | 14793 | STU_RS14645 | 0.0 | Capsule | Immune modulation | 98.36 | 100.00 | WP_011226048 |
| CIJKMGPI_50 | 14794 | 16248 | STR_RS05265 | 0.0 | Capsule | Immune modulation | 98.35 | 100.00 | WP_041827043 |
| CIJKMGPI_50 | 2634 | 4049 | STER_RS05250 | 0.0 | Capsule | Immune modulation | 98.31 | 100.00 | WP_011681165 |
| CIJKMGPI_20 | 1389 | 2177 | cshA | 0.0 | Cell surface hydrophobicity proteins | Adherence | 98.23 | 99.75 | - |
| CIJKMGPI_50 | 14062 | 14793 | STR_RS05260 | 0.0 | Capsule | Immune modulation | 98.22 | 100.00 | WP_011227248 |
| CIJKMGPI_1 | 192239 | 192954 | STER_RS07085 | 0.0 | Capsule | Immune modulation | 98.18 | 99.86 | WP_011681442 |
| CIJKMGPI_50 | 14794 | 16248 | STU_RS14650 | 0.0 | Capsule | Immune modulation | 98.01 | 100.00 | WP_011226049 |
| CIJKMGPI_1 | 193300 | 194076 | STER_RS07075 | 0.0 | Capsule | Immune modulation | 97.81 | 100.00 | WP_011681440 |
| CIJKMGPI_50 | 12611 | 13351 | STU_RS14635 | 0.0 | Capsule | Immune modulation | 97.71 | 100.00 | WP_011226046 |
| CIJKMGPI_50 | 13361 | 14053 | STR_RS05255 | 0.0 | Capsule | Immune modulation | 97.69 | 100.00 | WP_011227247 |
| CIJKMGPI_50 | 13361 | 14053 | STU_RS14640 | 0.0 | Capsule | Immune modulation | 97.69 | 100.00 | WP_011226047 |
| CIJKMGPI_50 | 12611 | 13351 | STER_RS05305 | 0.0 | Capsule | Immune modulation | 97.57 | 100.00 | WP_011681174 |
| CIJKMGPI_1 | 188048 | 188899 | rfbD | 0.0 | Capsule | Immune modulation | 97.30 | 100.00 | WP_014621820 |
| CIJKMGPI_50 | 12616 | 13351 | STR_RS05250 | 0.0 | Capsule | Immune modulation | 97.28 | 98.13 | WP_011227246 |
| CIJKMGPI_50 | 14794 | 16248 | STER_RS05320 | 0.0 | Capsule | Immune modulation | 97.12 | 99.79 | WP_011681177 |
| CIJKMGPI_12 | 18388 | 19380 | cbpD | 0.0 | Autolysin | Exoenzyme | 96.47 | 102.37 | WP_082302295 |
| CIJKMGPI_50 | 11187 | 12554 | STU_RS14630 | 0.0 | Capsule | Immune modulation | 95.25 | 100.00 | WP_011226045 |
| CIJKMGPI_2 | 28820 | 33764 | SSU98_0978 | 0.0 | Agglutinin receptor | Adherence | 94.28 | 99.80 | YP_001200536 |
| CIJKMGPI_2 | 28820 | 33764 | SSU05_0965 | 0.0 | Agglutinin receptor | Adherence | 94.26 | 99.80 | YP_001198331 |
| CIJKMGPI_2 | 28869 | 33764 | SAG_RS09105 | 0.0 | Agglutinin receptor | Adherence | 94.18 | 100.00 | WP_000167699 |
| CIJKMGPI_50 | 11189 | 12554 | STER_RS05300 | 0.0 | Capsule | Immune modulation | 93.27 | 99.85 | WP_011681173 |
| CIJKMGPI_50 | 13361 | 14053 | STER_RS05310 | 0.0 | Capsule | Immune modulation | 91.05 | 100.00 | WP_011681175 |
| CIJKMGPI_12 | 176659 | 177962 | eno | 0.0 | Streptococcal enolase | Exoenzyme | 88.09 | 99.54 | WP_000022832 |
| CIJKMGPI_45 | 84804 | 85814 | plr/gapA | 0.0 | Streptococcal plasmin receptor/GAPDH | Adherence | 87.45 | 99.90 | WP_002986042 |
| CIJKMGPI_23 | 177426 | 178472 | rfbB | 0.0 | Capsule | Immune modulation | 80.42 | 100.00 | WP_009659423 |
| CIJKMGPI_51 | 63046 | 64329 | tig/ropA | 0.0 | Trigger factor | Stress survival | 80.19 | 99.77 | WP_000107753 |
| CIJKMGPI_50 | 266 | 852 | SPD_RS01775 | 4.35e-143 | Capsule | Immune modulation | 82.48 | 96.70 | WP_001819836 |
BLASTN v2.16.0 (Database: VFDB, Dec. 2024 release)
VirulenceFinder
| Query ID | Begin | End | Database | Virulence factor | Protein function | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
VirulenceFinder v2.0. 4 (Database: virulencefinder_db, Feb . 2024 release)
Pathogenic genes
PHI-base
| Query ID | qstart | qend | Gene name | e-value | Function | Identity | Coverage | Gene ID |
|---|---|---|---|---|---|---|---|---|
| CIJKMGPI_2 | 28833 | 33761 | B9H01_RS04765 | 0.0 | glucan-binding protein | 94.83 | 100.00 | AUS90958 |
| CIJKMGPI_23 | 138188 | 137205 | ldh(Sp_1220) | 0.0 | L-lactate dehydrogenase | 94.82 | 100.00 | AAK75326 |
| CIJKMGPI_34 | 44447 | 43374 | MntE | 0.0 | manganese homeostasis | 94.69 | 99.72 | ABF32167 |
| CIJKMGPI_1 | 15607 | 13304 | pfl2(Sp_0459) | 0.0 | formate acetyltransferase | 92.97 | 99.22 | AAK74619 |
| CIJKMGPI_12 | 94934 | 95902 | spr0084 | 0.0 | pathogenitcity related | 92.88 | 98.48 | AAK98888 |
| CIJKMGPI_23 | 68132 | 66651 | SPD_0310 | 0.0 | UPF0371 protein SPD_0310 | 92.11 | 100.00 | ABJ54480 |
| CIJKMGPI_34 | 11366 | 9120 | metE | 0.0 | methionine biosynthesis enzymes | 91.99 | 100.00 | AAK74738 |
| CIJKMGPI_16 | 2062 | 1064 | recA | 0.0 | DNA recombination and repair | 91.29 | 85.82 | AAL00560 |
| CIJKMGPI_18 | 15392 | 14421 | prsA2 | 0.0 | ribose-phosphate pyrophosphokinase | 90.12 | 100.00 | ABF36968 |
| CIJKMGPI_1 | 138977 | 140128 | potA | 0.0 | ABC transporter ATP-binding protein-spermidine/putrescine transport | 89.32 | 99.74 | AAL00050 |
| CIJKMGPI_1 | 174799 | 176787 | uvrB | 0.0 | excinuclease ABC, B subunit | 88.99 | 100.00 | AE014259_2 |
| CIJKMGPI_52 | 28707 | 30185 | IMPDH | 0.0 | inosine-5'-monophosphate dehydrogenase | 87.63 | 100.00 | ADE32434 |
| CIJKMGPI_23 | 154383 | 156113 | ptsI | 0.0 | phosphoenolpyruvate-protein phosphotransferase | 87.52 | 100.00 | AAK34199 |
| CIJKMGPI_52 | 43442 | 45334 | gidA | 0.0 | tRNA uridine 5-carboxymethylaminomethyl modification enzyme | 86.05 | 98.90 | ABP91129 |
| CIJKMGPI_12 | 176659 | 177960 | Eno | 0.0 | enolase | 85.98 | 99.77 | ABP90468 |
| CIJKMGPI_34 | 6195 | 7904 | PGM | 0.0 | phosphoglucomutase | 83.89 | 99.65 | ACH87041 |
| CIJKMGPI_25 | 2103 | 1093 | pdh | 0.0 | pyruvate dehydrogenase | 83.09 | 99.70 | ABP91006 |
| CIJKMGPI_53 | 38627 | 39988 | mnmE | 0.0 | central tRNA-modifying GTPase | 82.24 | 99.56 | ABP90420 |
| CIJKMGPI_12 | 162234 | 163124 | bglB | 1.53e-179 | putative phospho--glucosidase | 88.89 | 99.66 | AAK33487 |
| CIJKMGPI_19 | 7028 | 7966 | SP_0676 | 2.30e-169 | transcription facot | 81.15 | 97.20 | AAK74821 |
| CIJKMGPI_34 | 8928 | 8071 | metF | 3.24e-165 | methionine biosynthesis enzymes | 86.01 | 99.31 | AAK74739 |
| CIJKMGPI_50 | 53064 | 52360 | covR | 6.28e-132 | responder protein | 85.53 | 100.00 | AAK71319 |
| CIJKMGPI_23 | 96213 | 96884 | rr01 | 1.58e-125 | response regulator | 83.93 | 99.56 | CAB54566 |
| CIJKMGPI_50 | 53064 | 52360 | walR | 3.43e-122 | DNA-binding response regulator | 81.70 | 100.00 | ANC99504 |
| CIJKMGPI_14 | 9209 | 8523 | CovR | 1.35e-119 | serves to repress GAS virulence factor-encoding genes | 80.79 | 100.00 | ACE75886 |
| CIJKMGPI_34 | 2238 | 1570 | CiaR | 6.56e-119 | two-component response regulator | 84.75 | 99.55 | AAK74935 |
| CIJKMGPI_34 | 2238 | 1567 | ciaR | 7.12e-117 | two component system response regulator | 82.59 | 99.12 | AIK75708 |
| CIJKMGPI_16 | 788 | 414 | SpxA2 | 2.69e-71 | transcriptional regulator | 90.40 | 94.70 | ERL21461 |
| CIJKMGPI_8 | 20164 | 19877 | spr0479 | 2.55e-49 | essential gene | 86.46 | 98.97 | AAK99283 |
| CIJKMGPI_12 | 60266 | 60520 | spr1327 | 3.17e-45 | essential gene | 95.29 | 100.00 | AAL00131 |
| CIJKMGPI_5 | 10365 | 10102 | spr0175 | 2.06e-42 | pathogenitcity related | 84.09 | 100.00 | AAK98979 |
| CIJKMGPI_5 | 9562 | 9272 | spr0177 | 1.21e-37 | essential gene | 81.00 | 98.02 | AAK98981 |
| CIJKMGPI_51 | 62888 | 62388 | RopE (M5005_Spy_1611) | 1.84e-76 | probable DNA-directed RNA polymerase subunit delta | 81.44 | 87.43 | AAK34603 |
| CIJKMGPI_1 | 15607 | 13310 | PFL (B9H01_RS01125) | 0.0 | formate C-acetyltransferase | 82.94 | 98.08 | MYN69560 |
| CIJKMGPI_3 | 18970 | 19989 | ilvC (SPD_0406) | 0.0 | ketol-acid reductoisomerase (NADP(+)) | 96.18 | 100.00 | ABJ55451 |
BLASTX v2.16.0 (Database: PHI base v4.16, May. 2024 release)
Plasmid
PlasmidFinder
| Query ID | Begin | End | Plasmid | Query / Template | Identity | Accession no. |
|---|---|---|---|---|---|---|
| No hit found | ||||||
PlasmidFinder v 2.1.6 (Database: plasmidfinder_db v 2.2.0 , Nov. 2024 release)
PlasmidHunter
| Query ID | Prediction | Chromosome | Plasmid |
|---|---|---|---|
| CIJKMGPI_1 | 0.0 | 1.0 | 0.0 |
| CIJKMGPI_2 | 0.0 | 1.0 | 0.0 |
| CIJKMGPI_3 | 0.0 | 1.0 | 0.0 |
| CIJKMGPI_4 | 0.0 | 1.0 | 0.0 |
| CIJKMGPI_5 | 0.0 | 1.0 | 0.0 |
| CIJKMGPI_6 | 0.0 | 1.0 | 0.0 |
| CIJKMGPI_7 | 0.0 | 1.0 | 0.0 |
| CIJKMGPI_8 | 0.0 | 1.0 | 0.0 |
| CIJKMGPI_9 | 0.0 | 1.0 | 0.0 |
| CIJKMGPI_10 | 0.0 | 1.0 | 0.0 |
| CIJKMGPI_11 | 0.0 | 1.0 | 0.0 |
| CIJKMGPI_12 | 0.0 | 1.0 | 0.0 |
| CIJKMGPI_13 | 0.0 | 1.0 | 0.0 |
| CIJKMGPI_14 | 0.0 | 1.0 | 0.0 |
| CIJKMGPI_15 | 0.0 | 1.0 | 0.0 |
| CIJKMGPI_16 | 0.0 | 1.0 | 0.0 |
| CIJKMGPI_17 | 0.0 | 1.0 | 0.0 |
| CIJKMGPI_18 | 0.0 | 1.0 | 0.0 |
| CIJKMGPI_19 | 0.0 | 1.0 | 0.0 |
| CIJKMGPI_20 | 0.0 | 1.0 | 0.0 |
| CIJKMGPI_21 | 0.0 | 1.0 | 0.0 |
| CIJKMGPI_22 | 1.0 | 0.0 | 1.0 |
| CIJKMGPI_23 | 0.0 | 1.0 | 0.0 |
| CIJKMGPI_24 | 0.0 | 1.0 | 0.0 |
| CIJKMGPI_25 | 0.0 | 1.0 | 0.0 |
| CIJKMGPI_26 | 0.0 | 1.0 | 0.0 |
| CIJKMGPI_27 | 0.0 | 1.0 | 0.0 |
| CIJKMGPI_28 | 0.0 | 1.0 | 0.0 |
| CIJKMGPI_29 | 1.0 | 0.0 | 1.0 |
| CIJKMGPI_31 | 0.0 | 1.0 | 0.0 |
| CIJKMGPI_32 | 1.0 | 0.0 | 1.0 |
| CIJKMGPI_33 | 1.0 | 0.0 | 1.0 |
| CIJKMGPI_34 | 0.0 | 1.0 | 0.0 |
| CIJKMGPI_35 | 0.0 | 1.0 | 0.0 |
| CIJKMGPI_36 | 0.0 | 1.0 | 0.0 |
| CIJKMGPI_37 | 0.0 | 1.0 | 0.0 |
| CIJKMGPI_38 | 0.0 | 1.0 | 0.0 |
| CIJKMGPI_39 | 0.0 | 1.0 | 0.0 |
| CIJKMGPI_40 | 1.0 | 0.0 | 1.0 |
| CIJKMGPI_41 | 0.0 | 1.0 | 0.0 |
| CIJKMGPI_42 | 0.0 | 1.0 | 0.0 |
| CIJKMGPI_45 | 0.0 | 1.0 | 0.0 |
| CIJKMGPI_50 | 0.0 | 1.0 | 0.0 |
| CIJKMGPI_51 | 0.0 | 1.0 | 0.0 |
| CIJKMGPI_52 | 0.0 | 1.0 | 0.0 |
| CIJKMGPI_53 | 0.0 | 1.0 | 0.0 |
PlasmidHunter v 1.4.5 (Database: May. 2024 release)
Prophage
Phigaro
| Query ID | Begin | End | Transposable | Taxonomy | pVOGs |
|---|---|---|---|---|---|
| No hit found | |||||
Phigaro v2.4.0 (Database: Jan. 2024 release)