Probiotic potential risk score
| ARGs | VFs | PGs | PPRS |
|---|---|---|---|
| 0 | 26 | 28 | 38.21 |
PPRS is classified as low-risk (≤4), medium-risk (4-6), and high-risk (≥6).
Antibiotic resistance genes
Comprehensive Antibiotic Resistance Database (CARD)
| Query ID | Begin | End | ARO name | ARO accession | CARD name | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
RGI v6.0.3 (Database: CARD Variants v4.0.2, Nov. 2023 release)
ResFinder
| Query ID | Begin | End | Resistance gene | Phenotype | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|
| No hit found | |||||||
ResFinder v4.6.0 (Database: resfinder_db, Aug. 2024 release)
AMRFinderPlus
| Query ID | Begin | End | Gene symbol | Sequence name | Method | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
AMRFinderPlus v4.0.3 (Database: Oct. 2024 release)
Virulence factors
Virulence Factor Database (VFDB)
| Query ID | qstart | qend | Gene name | e-value | VF name | VF category | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|---|
| DBALAGAI_1 | 43633 | 44472 | cbpD | 0.0 | Autolysin | Exoenzyme | 100.00 | 100.00 | WP_011226733 |
| DBALAGAI_1 | 1080104 | 1080697 | STR_RS05880 | 0.0 | Capsule | Immune modulation | 99.83 | 100.00 | WP_011226149 |
| DBALAGAI_1 | 1080104 | 1080697 | STER_RS06030 | 0.0 | Capsule | Immune modulation | 99.66 | 100.00 | WP_011226149 |
| DBALAGAI_1 | 1080104 | 1080697 | STU_RS15260 | 0.0 | Capsule | Immune modulation | 99.66 | 100.00 | WP_011226149 |
| DBALAGAI_1 | 1285998 | 1286849 | rfbD | 0.0 | Capsule | Immune modulation | 99.53 | 100.00 | WP_014621820 |
| DBALAGAI_1 | 845862 | 847520 | fbp54 | 0.0 | FBPs | Adherence | 99.46 | 100.00 | WP_011227179 |
| DBALAGAI_1 | 966856 | 967455 | STR_RS05245 | 0.0 | Capsule | Immune modulation | 99.33 | 100.00 | WP_196767671 |
| DBALAGAI_1 | 1281358 | 1282502 | STU_RS16255 | 0.0 | Capsule | Immune modulation | 99.30 | 99.83 | WP_041828290 |
| DBALAGAI_1 | 1275596 | 1277376 | STU_RS16230 | 0.0 | Capsule | Immune modulation | 99.22 | 99.78 | WP_011226325 |
| DBALAGAI_1 | 1080697 | 1081566 | rfbA | 0.0 | Capsule | Immune modulation | 99.08 | 100.00 | WP_011681286 |
| DBALAGAI_1 | 945677 | 947092 | STER_RS05250 | 0.0 | Capsule | Immune modulation | 99.01 | 100.00 | WP_011681165 |
| DBALAGAI_1 | 1279629 | 1280431 | STU_RS16245 | 0.0 | Capsule | Immune modulation | 99.01 | 99.14 | WP_002948020 |
| DBALAGAI_1 | 1035578 | 1036368 | cshA | 0.0 | Cell surface hydrophobicity proteins | Adherence | 98.99 | 100.00 | - |
| DBALAGAI_1 | 1282611 | 1283621 | STU_RS16260 | 0.0 | Capsule | Immune modulation | 98.91 | 100.00 | WP_011226330 |
| DBALAGAI_1 | 1115457 | 1116218 | srtA | 0.0 | Sortase A | Exoenzyme | 98.82 | 100.00 | - |
| DBALAGAI_1 | 969791 | 971245 | STU_RS14650 | 0.0 | Capsule | Immune modulation | 98.76 | 100.00 | WP_011226049 |
| DBALAGAI_1 | 1280415 | 1281361 | STU_RS16250 | 0.0 | Capsule | Immune modulation | 98.75 | 99.27 | WP_011226328 |
| DBALAGAI_1 | 969791 | 971245 | STR_RS05265 | 0.0 | Capsule | Immune modulation | 98.62 | 100.00 | WP_041827043 |
| DBALAGAI_1 | 1277373 | 1278418 | STU_RS16235 | 0.0 | Capsule | Immune modulation | 98.58 | 99.05 | WP_002948022 |
| DBALAGAI_1 | 1278437 | 1279629 | STU_RS16240 | 0.0 | Capsule | Immune modulation | 98.42 | 99.17 | WP_011226326 |
| DBALAGAI_1 | 965732 | 966691 | STR_RS05240 | 0.0 | Capsule | Immune modulation | 98.23 | 100.00 | WP_041827042 |
| DBALAGAI_1 | 1283621 | 1284895 | STU_RS16265 | 0.0 | Capsule | Immune modulation | 98.20 | 100.00 | WP_011226331 |
| DBALAGAI_1 | 967607 | 968342 | STER_RS05305 | 0.0 | Capsule | Immune modulation | 97.96 | 99.33 | WP_011681174 |
| DBALAGAI_1 | 967607 | 968342 | STU_RS14635 | 0.0 | Capsule | Immune modulation | 97.83 | 99.33 | WP_011226046 |
| DBALAGAI_1 | 969059 | 969790 | STER_RS05315 | 0.0 | Capsule | Immune modulation | 97.68 | 100.00 | WP_011681176 |
| DBALAGAI_1 | 967593 | 968342 | STR_RS05250 | 0.0 | Capsule | Immune modulation | 97.47 | 100.00 | WP_011227246 |
| DBALAGAI_1 | 969059 | 969790 | STU_RS14645 | 0.0 | Capsule | Immune modulation | 97.27 | 100.00 | WP_011226048 |
| DBALAGAI_1 | 969791 | 971245 | STER_RS05320 | 0.0 | Capsule | Immune modulation | 97.06 | 99.79 | WP_011681177 |
| DBALAGAI_1 | 969059 | 969790 | STR_RS05260 | 0.0 | Capsule | Immune modulation | 96.86 | 100.00 | WP_011227248 |
| DBALAGAI_1 | 968352 | 969033 | STU_RS14640 | 0.0 | Capsule | Immune modulation | 93.25 | 98.41 | WP_011226047 |
| DBALAGAI_1 | 968352 | 969033 | STR_RS05255 | 0.0 | Capsule | Immune modulation | 92.96 | 98.41 | WP_011227247 |
| DBALAGAI_1 | 597515 | 598818 | eno | 0.0 | Streptococcal enolase | Exoenzyme | 87.86 | 99.54 | WP_000022832 |
| DBALAGAI_1 | 1570443 | 1571453 | plr/gapA | 0.0 | Streptococcal plasmin receptor/GAPDH | Adherence | 86.92 | 99.51 | WP_002986042 |
| DBALAGAI_1 | 968352 | 969033 | STER_RS05310 | 0.0 | Capsule | Immune modulation | 85.92 | 98.41 | WP_011681175 |
| DBALAGAI_1 | 146477 | 147760 | tig/ropA | 0.0 | Trigger factor | Stress survival | 80.58 | 99.77 | WP_000107753 |
| DBALAGAI_1 | 1078629 | 1079675 | rfbB | 0.0 | Capsule | Immune modulation | 80.33 | 100.00 | WP_009659423 |
BLASTN v2.16.0 (Database: VFDB, Dec. 2024 release)
VirulenceFinder
| Query ID | Begin | End | Database | Virulence factor | Protein function | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
VirulenceFinder v2.0. 4 (Database: virulencefinder_db, Feb . 2024 release)
Pathogenic genes
PHI-base
| Query ID | qstart | qend | Gene name | e-value | Function | Identity | Coverage | Gene ID |
|---|---|---|---|---|---|---|---|---|
| DBALAGAI_1 | 1118905 | 1119888 | ldh(Sp_1220) | 0.0 | L-lactate dehydrogenase | 94.82 | 100.00 | AAK75326 |
| DBALAGAI_1 | 699470 | 700543 | MntE | 0.0 | manganese homeostasis | 94.41 | 99.72 | ABF32167 |
| DBALAGAI_1 | 1449778 | 1452081 | pfl2(Sp_0459) | 0.0 | formate acetyltransferase | 93.10 | 99.22 | AAK74619 |
| DBALAGAI_1 | 515307 | 516275 | spr0084 | 0.0 | pathogenitcity related | 92.57 | 98.48 | AAK98888 |
| DBALAGAI_1 | 1191020 | 1192501 | SPD_0310 | 0.0 | UPF0371 protein SPD_0310 | 92.11 | 100.00 | ABJ54480 |
| DBALAGAI_1 | 727719 | 729965 | metE | 0.0 | methionine biosynthesis enzymes | 91.99 | 100.00 | AAK74738 |
| DBALAGAI_1 | 64577 | 65575 | recA | 0.0 | DNA recombination and repair | 91.29 | 85.82 | AAL00560 |
| DBALAGAI_1 | 27151 | 28122 | prsA2 | 0.0 | ribose-phosphate pyrophosphokinase | 90.12 | 100.00 | ABF36968 |
| DBALAGAI_1 | 1329825 | 1328674 | potA | 0.0 | ABC transporter ATP-binding protein-spermidine/putrescine transport | 89.32 | 99.74 | AAL00050 |
| DBALAGAI_1 | 1301819 | 1299831 | uvrB | 0.0 | excinuclease ABC, B subunit | 88.99 | 100.00 | AE014259_2 |
| DBALAGAI_1 | 1102712 | 1100982 | ptsI | 0.0 | phosphoenolpyruvate-protein phosphotransferase | 87.69 | 100.00 | AAK34199 |
| DBALAGAI_1 | 1761024 | 1759546 | IMPDH | 0.0 | inosine-5'-monophosphate dehydrogenase | 87.63 | 100.00 | ADE32434 |
| DBALAGAI_1 | 597515 | 598816 | Eno | 0.0 | enolase | 86.21 | 99.77 | ABP90468 |
| DBALAGAI_1 | 1745829 | 1743937 | gidA | 0.0 | tRNA uridine 5-carboxymethylaminomethyl modification enzyme | 86.05 | 98.90 | ABP91129 |
| DBALAGAI_1 | 732891 | 731182 | PGM | 0.0 | phosphoglucomutase | 83.89 | 99.65 | ACH87041 |
| DBALAGAI_1 | 1614100 | 1615110 | pdh | 0.0 | pyruvate dehydrogenase | 83.09 | 99.70 | ABP91006 |
| DBALAGAI_1 | 874131 | 872770 | mnmE | 0.0 | central tRNA-modifying GTPase | 82.02 | 99.56 | ABP90420 |
| DBALAGAI_1 | 1664365 | 1662473 | PepO | 0.0 | endopeptidase | 80.03 | 100.00 | ABF32980 |
| DBALAGAI_1 | 583084 | 583974 | bglB | 2.79e-178 | putative phospho--glucosidase | 88.55 | 99.66 | AAK33487 |
| DBALAGAI_1 | 792235 | 791297 | SP_0676 | 7.86e-168 | transcription facot | 81.47 | 97.20 | AAK74821 |
| DBALAGAI_1 | 730157 | 731014 | metF | 1.43e-164 | methionine biosynthesis enzymes | 86.01 | 99.31 | AAK74739 |
| DBALAGAI_1 | 1007946 | 1007242 | covR | 6.47e-131 | responder protein | 85.53 | 100.00 | AAK71319 |
| DBALAGAI_1 | 1172051 | 1171380 | rr01 | 5.29e-125 | response regulator | 84.38 | 99.56 | CAB54566 |
| DBALAGAI_1 | 1007946 | 1007242 | walR | 3.06e-121 | DNA-binding response regulator | 81.70 | 100.00 | ANC99504 |
| DBALAGAI_1 | 736845 | 737513 | CiaR | 3.77e-120 | two-component response regulator | 85.65 | 99.55 | AAK74935 |
| DBALAGAI_1 | 736845 | 737516 | ciaR | 5.36e-118 | two component system response regulator | 83.48 | 99.12 | AIK75708 |
| DBALAGAI_1 | 295394 | 296080 | CovR | 3.84e-117 | serves to repress GAS virulence factor-encoding genes | 80.35 | 100.00 | ACE75886 |
| DBALAGAI_1 | 885488 | 885889 | SpxA1 | 3.60e-66 | transcriptional regulator | 80.60 | 100.00 | ERL19273 |
| DBALAGAI_1 | 147918 | 148418 | RopE (M5005_Spy_1611) | 4.71e-75 | probable DNA-directed RNA polymerase subunit delta | 81.44 | 87.43 | AAK34603 |
| DBALAGAI_1 | 1449778 | 1452075 | PFL (B9H01_RS01125) | 0.0 | formate C-acetyltransferase | 83.07 | 98.08 | MYN69560 |
| DBALAGAI_1 | 1649965 | 1648946 | ilvC (SPD_0406) | 0.0 | ketol-acid reductoisomerase (NADP(+)) | 96.47 | 100.00 | ABJ55451 |
BLASTX v2.16.0 (Database: PHI base v4.16, May. 2024 release)
Plasmid
PlasmidFinder
| Query ID | Begin | End | Plasmid | Query / Template | Identity | Accession no. |
|---|---|---|---|---|---|---|
| No hit found | ||||||
PlasmidFinder v 2.1.6 (Database: plasmidfinder_db v 2.2.0 , Nov. 2024 release)
PlasmidHunter
| Query ID | Prediction | Chromosome | Plasmid |
|---|---|---|---|
| DBALAGAI_1 | 0.0 | 1.0 | 0.0 |
PlasmidHunter v 1.4.5 (Database: May. 2024 release)
Prophage
Phigaro
| Query ID | Begin | End | Transposable | Taxonomy | pVOGs |
|---|---|---|---|---|---|
| No hit found | |||||
Phigaro v2.4.0 (Database: Jan. 2024 release)