Probiotic potential risk score
| ARGs | VFs | PGs | PPRS |
|---|---|---|---|
| 0 | 28 | 28 | 39.60 |
PPRS is classified as low-risk (≤4), medium-risk (4-6), and high-risk (≥6).
Antibiotic resistance genes
Comprehensive Antibiotic Resistance Database (CARD)
| Query ID | Begin | End | ARO name | ARO accession | CARD name | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
RGI v6.0.3 (Database: CARD Variants v4.0.2, Nov. 2023 release)
ResFinder
| Query ID | Begin | End | Resistance gene | Phenotype | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|
| No hit found | |||||||
ResFinder v4.6.0 (Database: resfinder_db, Aug. 2024 release)
AMRFinderPlus
| Query ID | Begin | End | Gene symbol | Sequence name | Method | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
AMRFinderPlus v4.0.3 (Database: Oct. 2024 release)
Virulence factors
Virulence Factor Database (VFDB)
| Query ID | qstart | qend | Gene name | e-value | VF name | VF category | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|---|
| OKLJPHFE_1 | 1321565 | 1322533 | STER_RS07090 | 0.0 | Capsule | Immune modulation | 100.00 | 100.00 | WP_011681443 |
| OKLJPHFE_1 | 1315513 | 1316715 | STER_RS07055 | 0.0 | Capsule | Immune modulation | 99.83 | 100.00 | WP_011681436 |
| OKLJPHFE_1 | 1318459 | 1319607 | STER_RS07070 | 0.0 | Capsule | Immune modulation | 99.83 | 100.00 | WP_011681439 |
| OKLJPHFE_1 | 1099809 | 1100402 | STR_RS05880 | 0.0 | Capsule | Immune modulation | 99.83 | 100.00 | WP_011226149 |
| OKLJPHFE_1 | 1313795 | 1315495 | STER_RS07050 | 0.0 | Capsule | Immune modulation | 99.82 | 100.00 | WP_041827753 |
| OKLJPHFE_1 | 1312048 | 1313793 | STR_RS06885 | 0.0 | Capsule | Immune modulation | 99.77 | 100.00 | WP_011227426 |
| OKLJPHFE_1 | 1317521 | 1318462 | STER_RS07065 | 0.0 | Capsule | Immune modulation | 99.68 | 100.00 | WP_011681438 |
| OKLJPHFE_1 | 1099809 | 1100402 | STER_RS06030 | 0.0 | Capsule | Immune modulation | 99.66 | 100.00 | WP_011226149 |
| OKLJPHFE_1 | 1099809 | 1100402 | STU_RS15260 | 0.0 | Capsule | Immune modulation | 99.66 | 100.00 | WP_011226149 |
| OKLJPHFE_1 | 1313795 | 1315495 | STR_RS06890 | 0.0 | Capsule | Immune modulation | 99.65 | 100.00 | WP_041827077 |
| OKLJPHFE_1 | 1315513 | 1316715 | STR_RS06895 | 0.0 | Capsule | Immune modulation | 99.58 | 100.00 | WP_011227428 |
| OKLJPHFE_1 | 1100402 | 1101271 | rfbA | 0.0 | Capsule | Immune modulation | 99.42 | 100.00 | WP_011681286 |
| OKLJPHFE_1 | 1322551 | 1323528 | STER_RS07095 | 0.0 | Capsule | Immune modulation | 99.39 | 100.00 | WP_011681444 |
| OKLJPHFE_1 | 1316715 | 1317521 | STER_RS07060 | 0.0 | Capsule | Immune modulation | 99.38 | 100.00 | WP_011681437 |
| OKLJPHFE_1 | 1317521 | 1318462 | STR_RS06905 | 0.0 | Capsule | Immune modulation | 99.36 | 100.00 | WP_011227430 |
| OKLJPHFE_1 | 1318459 | 1319607 | STR_RS06910 | 0.0 | Capsule | Immune modulation | 99.22 | 100.00 | WP_011227431 |
| OKLJPHFE_1 | 851125 | 852783 | fbp54 | 0.0 | FBPs | Adherence | 99.16 | 100.00 | WP_011227179 |
| OKLJPHFE_1 | 1316715 | 1317521 | STR_RS06900 | 0.0 | Capsule | Immune modulation | 99.13 | 100.00 | WP_011227429 |
| OKLJPHFE_1 | 968250 | 968981 | STU_RS14645 | 0.0 | Capsule | Immune modulation | 98.77 | 100.00 | WP_011226048 |
| OKLJPHFE_1 | 968250 | 968981 | STR_RS05260 | 0.0 | Capsule | Immune modulation | 98.63 | 100.00 | WP_011227248 |
| OKLJPHFE_1 | 1046509 | 1047297 | cshA | 0.0 | Cell surface hydrophobicity proteins | Adherence | 98.61 | 99.75 | - |
| OKLJPHFE_1 | 1135165 | 1135926 | srtA | 0.0 | Sortase A | Exoenzyme | 98.56 | 100.00 | - |
| OKLJPHFE_1 | 966799 | 967539 | STER_RS05305 | 0.0 | Capsule | Immune modulation | 98.52 | 100.00 | WP_011681174 |
| OKLJPHFE_1 | 968250 | 968981 | STER_RS05315 | 0.0 | Capsule | Immune modulation | 98.50 | 100.00 | WP_011681176 |
| OKLJPHFE_1 | 1320848 | 1321564 | STER_RS07085 | 0.0 | Capsule | Immune modulation | 98.33 | 100.00 | WP_011681442 |
| OKLJPHFE_1 | 1312048 | 1313793 | STER_RS07045 | 0.0 | Capsule | Immune modulation | 98.11 | 100.00 | WP_011681434 |
| OKLJPHFE_1 | 966799 | 967539 | STU_RS14635 | 0.0 | Capsule | Immune modulation | 98.11 | 100.00 | WP_011226046 |
| OKLJPHFE_1 | 1324902 | 1325753 | rfbD | 0.0 | Capsule | Immune modulation | 98.00 | 100.00 | WP_014621820 |
| OKLJPHFE_1 | 968982 | 970442 | STER_RS05320 | 0.0 | Capsule | Immune modulation | 97.88 | 100.00 | WP_011681177 |
| OKLJPHFE_1 | 966804 | 967539 | STR_RS05250 | 0.0 | Capsule | Immune modulation | 97.83 | 98.13 | WP_011227246 |
| OKLJPHFE_1 | 1319726 | 1320502 | STER_RS07075 | 0.0 | Capsule | Immune modulation | 97.04 | 99.87 | WP_011681440 |
| OKLJPHFE_1 | 968982 | 970442 | STU_RS14650 | 0.0 | Capsule | Immune modulation | 96.85 | 100.21 | WP_011226049 |
| OKLJPHFE_1 | 967549 | 968241 | STU_RS14640 | 0.0 | Capsule | Immune modulation | 96.68 | 100.00 | WP_011226047 |
| OKLJPHFE_1 | 1323525 | 1324783 | STER_RS07100 | 0.0 | Capsule | Immune modulation | 96.51 | 99.92 | WP_011681445 |
| OKLJPHFE_1 | 967549 | 968241 | STR_RS05255 | 0.0 | Capsule | Immune modulation | 96.39 | 100.00 | WP_011227247 |
| OKLJPHFE_1 | 968982 | 970442 | STR_RS05265 | 0.0 | Capsule | Immune modulation | 96.23 | 100.21 | WP_041827043 |
| OKLJPHFE_1 | 965377 | 966742 | STER_RS05300 | 0.0 | Capsule | Immune modulation | 95.61 | 99.85 | WP_011681173 |
| OKLJPHFE_1 | 965375 | 966742 | STU_RS14630 | 0.0 | Capsule | Immune modulation | 94.66 | 100.00 | WP_011226045 |
| OKLJPHFE_1 | 967549 | 968241 | STER_RS05310 | 0.0 | Capsule | Immune modulation | 92.06 | 100.00 | WP_011681175 |
| OKLJPHFE_1 | 21766 | 22605 | cbpD | 0.0 | Autolysin | Exoenzyme | 90.00 | 100.00 | WP_011226733 |
| OKLJPHFE_1 | 595280 | 596583 | eno | 0.0 | Streptococcal enolase | Exoenzyme | 88.02 | 99.46 | WP_000022832 |
| OKLJPHFE_1 | 1610407 | 1611417 | plr/gapA | 0.0 | Streptococcal plasmin receptor/GAPDH | Adherence | 86.43 | 99.51 | WP_002986042 |
| OKLJPHFE_1 | 1316715 | 1317521 | SGO_RS05020 | 0.0 | Capsule | Immune modulation | 83.27 | 100.00 | WP_012000440 |
| OKLJPHFE_1 | 1098333 | 1099379 | rfbB | 0.0 | Capsule | Immune modulation | 80.61 | 100.00 | WP_009659423 |
| OKLJPHFE_1 | 111389 | 112672 | tig/ropA | 0.0 | Trigger factor | Stress survival | 80.50 | 99.77 | WP_000107753 |
| OKLJPHFE_1 | 957215 | 957798 | SPD_RS01775 | 5.17e-145 | Capsule | Immune modulation | 82.91 | 96.20 | WP_001819836 |
| OKLJPHFE_1 | 1315978 | 1316715 | SGO_RS05025 | 0.0 | Capsule | Immune modulation | 84.96 | 60.29 | WP_012000441 |
BLASTN v2.16.0 (Database: VFDB, Dec. 2024 release)
VirulenceFinder
| Query ID | Begin | End | Database | Virulence factor | Protein function | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
VirulenceFinder v2.0. 4 (Database: virulencefinder_db, Feb . 2024 release)
Pathogenic genes
PHI-base
| Query ID | qstart | qend | Gene name | e-value | Function | Identity | Coverage | Gene ID |
|---|---|---|---|---|---|---|---|---|
| OKLJPHFE_1 | 707339 | 708412 | MntE | 0.0 | manganese homeostasis | 94.97 | 99.72 | ABF32167 |
| OKLJPHFE_1 | 1138613 | 1139596 | ldh(Sp_1220) | 0.0 | L-lactate dehydrogenase | 94.51 | 100.00 | AAK75326 |
| OKLJPHFE_1 | 1479035 | 1481338 | pfl2(Sp_0459) | 0.0 | formate acetyltransferase | 92.97 | 99.22 | AAK74619 |
| OKLJPHFE_1 | 512966 | 513934 | spr0084 | 0.0 | pathogenitcity related | 92.88 | 98.48 | AAK98888 |
| OKLJPHFE_1 | 1212903 | 1214384 | SPD_0310 | 0.0 | UPF0371 protein SPD_0310 | 91.90 | 100.00 | ABJ54480 |
| OKLJPHFE_1 | 727867 | 730113 | metE | 0.0 | methionine biosynthesis enzymes | 91.86 | 100.00 | AAK74738 |
| OKLJPHFE_1 | 44443 | 45441 | recA | 0.0 | DNA recombination and repair | 91.29 | 85.82 | AAL00560 |
| OKLJPHFE_1 | 6488 | 7459 | prsA2 | 0.0 | ribose-phosphate pyrophosphokinase | 90.12 | 100.00 | ABF36968 |
| OKLJPHFE_1 | 1367280 | 1366129 | potA | 0.0 | ABC transporter ATP-binding protein-spermidine/putrescine transport | 89.32 | 99.74 | AAL00050 |
| OKLJPHFE_1 | 1339286 | 1337298 | uvrB | 0.0 | excinuclease ABC, B subunit | 88.84 | 100.00 | AE014259_2 |
| OKLJPHFE_1 | 1122422 | 1120692 | ptsI | 0.0 | phosphoenolpyruvate-protein phosphotransferase | 88.56 | 100.00 | AAK34199 |
| OKLJPHFE_1 | 1791090 | 1789612 | IMPDH | 0.0 | inosine-5'-monophosphate dehydrogenase | 87.83 | 100.00 | ADE32434 |
| OKLJPHFE_1 | 595280 | 596581 | Eno | 0.0 | enolase | 86.44 | 99.77 | ABP90468 |
| OKLJPHFE_1 | 1776031 | 1774139 | gidA | 0.0 | tRNA uridine 5-carboxymethylaminomethyl modification enzyme | 85.74 | 98.90 | ABP91129 |
| OKLJPHFE_1 | 733038 | 731329 | PGM | 0.0 | phosphoglucomutase | 84.06 | 99.65 | ACH87041 |
| OKLJPHFE_1 | 1649198 | 1650208 | pdh | 0.0 | pyruvate dehydrogenase | 82.79 | 99.70 | ABP91006 |
| OKLJPHFE_1 | 885654 | 884293 | mnmE | 0.0 | central tRNA-modifying GTPase | 81.80 | 99.56 | ABP90420 |
| OKLJPHFE_1 | 1699711 | 1697819 | PepO | 0.0 | endopeptidase | 80.19 | 100.00 | ABF32980 |
| OKLJPHFE_1 | 580851 | 581741 | bglB | 1.35e-178 | putative phospho--glucosidase | 88.89 | 99.66 | AAK33487 |
| OKLJPHFE_1 | 791835 | 790897 | SP_0676 | 2.39e-167 | transcription facot | 81.15 | 97.20 | AAK74821 |
| OKLJPHFE_1 | 730305 | 731162 | metF | 1.83e-165 | methionine biosynthesis enzymes | 86.71 | 99.31 | AAK74739 |
| OKLJPHFE_1 | 1008148 | 1007444 | covR | 3.53e-130 | responder protein | 84.68 | 100.00 | AAK71319 |
| OKLJPHFE_1 | 1193932 | 1193261 | rr01 | 1.29e-125 | response regulator | 84.38 | 99.56 | CAB54566 |
| OKLJPHFE_1 | 736991 | 737659 | CiaR | 9.13e-124 | two-component response regulator | 87.00 | 99.55 | AAK74935 |
| OKLJPHFE_1 | 736991 | 737662 | ciaR | 2.58e-121 | two component system response regulator | 84.82 | 99.12 | AIK75708 |
| OKLJPHFE_1 | 1008148 | 1007444 | walR | 9.25e-121 | DNA-binding response regulator | 81.70 | 100.00 | ANC99504 |
| OKLJPHFE_1 | 267829 | 268515 | CovR | 1.02e-117 | serves to repress GAS virulence factor-encoding genes | 80.79 | 100.00 | ACE75886 |
| OKLJPHFE_1 | 45717 | 46112 | SpxA2 | 3.76e-74 | transcriptional regulator | 90.91 | 100.00 | ERL21461 |
| OKLJPHFE_1 | 112830 | 113330 | RopE (M5005_Spy_1611) | 9.47e-75 | probable DNA-directed RNA polymerase subunit delta | 81.44 | 87.43 | AAK34603 |
| OKLJPHFE_1 | 1479035 | 1481332 | PFL (B9H01_RS01125) | 0.0 | formate C-acetyltransferase | 82.94 | 98.08 | MYN69560 |
| OKLJPHFE_1 | 1685326 | 1684307 | ilvC (SPD_0406) | 0.0 | ketol-acid reductoisomerase (NADP(+)) | 96.18 | 100.00 | ABJ55451 |
BLASTX v2.16.0 (Database: PHI base v4.16, May. 2024 release)
Plasmid
PlasmidFinder
| Query ID | Begin | End | Plasmid | Query / Template | Identity | Accession no. |
|---|---|---|---|---|---|---|
| No hit found | ||||||
PlasmidFinder v 2.1.6 (Database: plasmidfinder_db v 2.2.0 , Nov. 2024 release)
PlasmidHunter
| Query ID | Prediction | Chromosome | Plasmid |
|---|---|---|---|
| OKLJPHFE_1 | 0.0 | 1.0 | 0.0 |
PlasmidHunter v 1.4.5 (Database: May. 2024 release)
Prophage
Phigaro
| Query ID | Begin | End | Transposable | Taxonomy | pVOGs |
|---|---|---|---|---|---|
| No hit found | |||||
Phigaro v2.4.0 (Database: Jan. 2024 release)