Probiotic potential risk score
| ARGs | VFs | PGs | PPRS |
|---|---|---|---|
| 0 | 23 | 29 | 37.01 |
PPRS is classified as low-risk (≤4), medium-risk (4-6), and high-risk (≥6).
Antibiotic resistance genes
Comprehensive Antibiotic Resistance Database (CARD)
| Query ID | Begin | End | ARO name | ARO accession | CARD name | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
RGI v6.0.3 (Database: CARD Variants v4.0.2, Nov. 2023 release)
ResFinder
| Query ID | Begin | End | Resistance gene | Phenotype | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|
| No hit found | |||||||
ResFinder v4.6.0 (Database: resfinder_db, Aug. 2024 release)
AMRFinderPlus
| Query ID | Begin | End | Gene symbol | Sequence name | Method | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
AMRFinderPlus v4.0.3 (Database: Oct. 2024 release)
Virulence factors
Virulence Factor Database (VFDB)
| Query ID | qstart | qend | Gene name | e-value | VF name | VF category | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|---|
| JPOGNOGE_1 | 271465 | 272334 | rfbA | 0.0 | Capsule | Immune modulation | 100.00 | 100.00 | WP_011681286 |
| JPOGNOGE_1 | 272334 | 272927 | STER_RS06030 | 0.0 | Capsule | Immune modulation | 100.00 | 100.00 | WP_011226149 |
| JPOGNOGE_1 | 58517 | 59326 | STU_RS16245 | 0.0 | Capsule | Immune modulation | 99.88 | 100.00 | WP_002948020 |
| JPOGNOGE_1 | 272334 | 272927 | STR_RS05880 | 0.0 | Capsule | Immune modulation | 99.83 | 100.00 | WP_011226149 |
| JPOGNOGE_1 | 272334 | 272927 | STU_RS15260 | 0.0 | Capsule | Immune modulation | 99.66 | 100.00 | WP_011226149 |
| JPOGNOGE_1 | 502802 | 504460 | fbp54 | 0.0 | FBPs | Adherence | 99.64 | 100.00 | WP_011227179 |
| JPOGNOGE_1 | 60551 | 61606 | STU_RS16235 | 0.0 | Capsule | Immune modulation | 99.62 | 100.00 | WP_002948022 |
| JPOGNOGE_1 | 1337130 | 1337969 | cbpD | 0.0 | Autolysin | Exoenzyme | 99.52 | 100.00 | WP_011226733 |
| JPOGNOGE_1 | 395402 | 396133 | STER_RS05315 | 0.0 | Capsule | Immune modulation | 99.32 | 100.00 | WP_011681176 |
| JPOGNOGE_1 | 59326 | 60531 | STU_RS16240 | 0.0 | Capsule | Immune modulation | 99.25 | 100.00 | WP_011226326 |
| JPOGNOGE_1 | 56432 | 57580 | STU_RS16255 | 0.0 | Capsule | Immune modulation | 99.22 | 100.00 | WP_041828290 |
| JPOGNOGE_1 | 57577 | 58533 | STU_RS16250 | 0.0 | Capsule | Immune modulation | 99.16 | 100.00 | WP_011226328 |
| JPOGNOGE_1 | 61603 | 63385 | STU_RS16230 | 0.0 | Capsule | Immune modulation | 99.10 | 99.89 | WP_011226325 |
| JPOGNOGE_1 | 395402 | 396133 | STU_RS14645 | 0.0 | Capsule | Immune modulation | 98.77 | 100.00 | WP_011226048 |
| JPOGNOGE_1 | 395402 | 396133 | STR_RS05260 | 0.0 | Capsule | Immune modulation | 98.63 | 100.00 | WP_011227248 |
| JPOGNOGE_1 | 328472 | 329265 | cshA | 0.0 | Cell surface hydrophobicity proteins | Adherence | 98.36 | 100.25 | - |
| JPOGNOGE_1 | 393941 | 395401 | STER_RS05320 | 0.0 | Capsule | Immune modulation | 98.29 | 100.00 | WP_011681177 |
| JPOGNOGE_1 | 236802 | 237563 | srtA | 0.0 | Sortase A | Exoenzyme | 97.64 | 100.00 | - |
| JPOGNOGE_1 | 396142 | 396834 | STU_RS14640 | 0.0 | Capsule | Immune modulation | 97.55 | 100.00 | WP_011226047 |
| JPOGNOGE_1 | 54157 | 55008 | rfbD | 0.0 | Capsule | Immune modulation | 97.30 | 100.00 | WP_014621820 |
| JPOGNOGE_1 | 396142 | 396834 | STR_RS05255 | 0.0 | Capsule | Immune modulation | 97.26 | 100.00 | WP_011227247 |
| JPOGNOGE_1 | 396844 | 397584 | STER_RS05305 | 0.0 | Capsule | Immune modulation | 97.03 | 100.00 | WP_011681174 |
| JPOGNOGE_1 | 396844 | 397584 | STU_RS14635 | 0.0 | Capsule | Immune modulation | 96.90 | 100.00 | WP_011226046 |
| JPOGNOGE_1 | 393941 | 395401 | STU_RS14650 | 0.0 | Capsule | Immune modulation | 96.85 | 100.21 | WP_011226049 |
| JPOGNOGE_1 | 396844 | 397579 | STR_RS05250 | 0.0 | Capsule | Immune modulation | 96.47 | 98.13 | WP_011227246 |
| JPOGNOGE_1 | 393941 | 395401 | STR_RS05265 | 0.0 | Capsule | Immune modulation | 95.89 | 100.21 | WP_041827043 |
| JPOGNOGE_1 | 397641 | 399008 | STU_RS14630 | 0.0 | Capsule | Immune modulation | 95.11 | 99.93 | WP_011226045 |
| JPOGNOGE_1 | 397641 | 399006 | STER_RS05300 | 0.0 | Capsule | Immune modulation | 94.66 | 99.78 | WP_011681173 |
| JPOGNOGE_1 | 396142 | 396834 | STER_RS05310 | 0.0 | Capsule | Immune modulation | 90.62 | 100.00 | WP_011681175 |
| JPOGNOGE_1 | 774094 | 775397 | eno | 0.0 | Streptococcal enolase | Exoenzyme | 88.10 | 99.46 | WP_000022832 |
| JPOGNOGE_1 | 1591902 | 1592912 | plr/gapA | 0.0 | Streptococcal plasmin receptor/GAPDH | Adherence | 87.46 | 99.80 | WP_002986042 |
| JPOGNOGE_1 | 1235250 | 1236533 | tig/ropA | 0.0 | Trigger factor | Stress survival | 80.73 | 99.77 | WP_000107753 |
| JPOGNOGE_1 | 273356 | 274402 | rfbB | 0.0 | Capsule | Immune modulation | 80.61 | 100.00 | WP_009659423 |
| JPOGNOGE_1 | 409267 | 409850 | SPD_RS01775 | 1.08e-146 | Capsule | Immune modulation | 83.08 | 96.20 | WP_001819836 |
BLASTN v2.16.0 (Database: VFDB, Dec. 2024 release)
VirulenceFinder
| Query ID | Begin | End | Database | Virulence factor | Protein function | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
VirulenceFinder v2.0. 4 (Database: virulencefinder_db, Feb . 2024 release)
Pathogenic genes
PHI-base
| Query ID | qstart | qend | Gene name | e-value | Function | Identity | Coverage | Gene ID |
|---|---|---|---|---|---|---|---|---|
| JPOGNOGE_1 | 234115 | 233132 | ldh(Sp_1220) | 0.0 | L-lactate dehydrogenase | 94.82 | 100.00 | AAK75326 |
| JPOGNOGE_1 | 659389 | 658316 | MntE | 0.0 | manganese homeostasis | 94.41 | 99.72 | ABF32167 |
| JPOGNOGE_1 | 1715042 | 1712739 | pfl2(Sp_0459) | 0.0 | formate acetyltransferase | 92.97 | 99.22 | AAK74619 |
| JPOGNOGE_1 | 857627 | 856659 | spr0084 | 0.0 | pathogenitcity related | 92.57 | 98.48 | AAK98888 |
| JPOGNOGE_1 | 163038 | 161557 | SPD_0310 | 0.0 | UPF0371 protein SPD_0310 | 92.31 | 100.00 | ABJ54480 |
| JPOGNOGE_1 | 638863 | 636617 | metE | 0.0 | methionine biosynthesis enzymes | 91.99 | 100.00 | AAK74738 |
| JPOGNOGE_1 | 1318338 | 1317340 | recA | 0.0 | DNA recombination and repair | 91.29 | 85.82 | AAL00560 |
| JPOGNOGE_1 | 1354451 | 1353480 | prsA2 | 0.0 | ribose-phosphate pyrophosphokinase | 90.12 | 100.00 | ABF36968 |
| JPOGNOGE_1 | 4506 | 5657 | potA | 0.0 | ABC transporter ATP-binding protein-spermidine/putrescine transport | 89.32 | 99.74 | AAL00050 |
| JPOGNOGE_1 | 40985 | 42973 | uvrB | 0.0 | excinuclease ABC, B subunit | 88.99 | 100.00 | AE014259_2 |
| JPOGNOGE_1 | 250314 | 252044 | ptsI | 0.0 | phosphoenolpyruvate-protein phosphotransferase | 88.39 | 100.00 | AAK34199 |
| JPOGNOGE_1 | 1394093 | 1395571 | IMPDH | 0.0 | inosine-5'-monophosphate dehydrogenase | 87.63 | 100.00 | ADE32434 |
| JPOGNOGE_1 | 775397 | 774096 | Eno | 0.0 | enolase | 86.21 | 99.77 | ABP90468 |
| JPOGNOGE_1 | 1408829 | 1410721 | gidA | 0.0 | tRNA uridine 5-carboxymethylaminomethyl modification enzyme | 85.74 | 98.90 | ABP91129 |
| JPOGNOGE_1 | 633692 | 635401 | PGM | 0.0 | phosphoglucomutase | 84.06 | 99.65 | ACH87041 |
| JPOGNOGE_1 | 1549497 | 1548487 | pdh | 0.0 | pyruvate dehydrogenase | 83.09 | 99.70 | ABP91006 |
| JPOGNOGE_1 | 477515 | 478876 | mnmE | 0.0 | central tRNA-modifying GTPase | 82.24 | 99.56 | ABP90420 |
| JPOGNOGE_1 | 1497493 | 1499385 | PepO | 0.0 | endopeptidase | 80.19 | 100.00 | ABF32980 |
| JPOGNOGE_1 | 789833 | 788943 | bglB | 1.32e-178 | putative phospho--glucosidase | 88.89 | 99.66 | AAK33487 |
| JPOGNOGE_1 | 562612 | 563550 | SP_0676 | 2.33e-167 | transcription facot | 81.15 | 97.20 | AAK74821 |
| JPOGNOGE_1 | 636425 | 635568 | metF | 2.52e-164 | methionine biosynthesis enzymes | 86.01 | 99.31 | AAK74739 |
| JPOGNOGE_1 | 357100 | 357804 | covR | 4.33e-131 | responder protein | 85.53 | 100.00 | AAK71319 |
| JPOGNOGE_1 | 182017 | 182688 | rr01 | 2.97e-124 | response regulator | 83.93 | 99.56 | CAB54566 |
| JPOGNOGE_1 | 629737 | 629069 | CiaR | 8.62e-123 | two-component response regulator | 86.10 | 99.55 | AAK74935 |
| JPOGNOGE_1 | 357100 | 357804 | walR | 1.82e-121 | DNA-binding response regulator | 82.13 | 100.00 | ANC99504 |
| JPOGNOGE_1 | 629737 | 629066 | ciaR | 1.17e-120 | two component system response regulator | 83.93 | 99.12 | AIK75708 |
| JPOGNOGE_1 | 1082112 | 1081426 | CovR | 3.06e-118 | serves to repress GAS virulence factor-encoding genes | 81.22 | 100.00 | ACE75886 |
| JPOGNOGE_1 | 1317064 | 1316690 | SpxA2 | 1.14e-69 | transcriptional regulator | 91.20 | 94.70 | ERL21461 |
| JPOGNOGE_1 | 466097 | 465696 | SpxA1 | 3.72e-66 | transcriptional regulator | 80.60 | 100.00 | ERL19273 |
| JPOGNOGE_1 | 1235092 | 1234592 | RopE (M5005_Spy_1611) | 4.86e-75 | probable DNA-directed RNA polymerase subunit delta | 81.44 | 87.43 | AAK34603 |
| JPOGNOGE_1 | 1715042 | 1712745 | PFL (B9H01_RS01125) | 0.0 | formate C-acetyltransferase | 82.94 | 98.08 | MYN69560 |
| JPOGNOGE_1 | 1511952 | 1512971 | ilvC (SPD_0406) | 0.0 | ketol-acid reductoisomerase (NADP(+)) | 96.47 | 100.00 | ABJ55451 |
BLASTX v2.16.0 (Database: PHI base v4.16, May. 2024 release)
Plasmid
PlasmidFinder
| Query ID | Begin | End | Plasmid | Query / Template | Identity | Accession no. |
|---|---|---|---|---|---|---|
| No hit found | ||||||
PlasmidFinder v 2.1.6 (Database: plasmidfinder_db v 2.2.0 , Nov. 2024 release)
PlasmidHunter
| Query ID | Prediction | Chromosome | Plasmid |
|---|---|---|---|
| JPOGNOGE_1 | 0.0 | 1.0 | 0.0 |
PlasmidHunter v 1.4.5 (Database: May. 2024 release)
Prophage
Phigaro
| Query ID | Begin | End | Transposable | Taxonomy | pVOGs |
|---|---|---|---|---|---|
| No hit found | |||||
Phigaro v2.4.0 (Database: Jan. 2024 release)