Probiotic potential risk score
| ARGs | VFs | PGs | PPRS |
|---|---|---|---|
| 0 | 22 | 28 | 35.61 |
PPRS is classified as low-risk (≤4), medium-risk (4-6), and high-risk (≥6).
Antibiotic resistance genes
Comprehensive Antibiotic Resistance Database (CARD)
| Query ID | Begin | End | ARO name | ARO accession | CARD name | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
RGI v6.0.3 (Database: CARD Variants v4.0.2, Nov. 2023 release)
ResFinder
| Query ID | Begin | End | Resistance gene | Phenotype | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|
| No hit found | |||||||
ResFinder v4.6.0 (Database: resfinder_db, Aug. 2024 release)
AMRFinderPlus
| Query ID | Begin | End | Gene symbol | Sequence name | Method | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
AMRFinderPlus v4.0.3 (Database: Oct. 2024 release)
Virulence factors
Virulence Factor Database (VFDB)
| Query ID | qstart | qend | Gene name | e-value | VF name | VF category | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|---|
| OACGODDC_1 | 1079571 | 1080164 | STR_RS05880 | 0.0 | Capsule | Immune modulation | 100.00 | 100.00 | WP_011226149 |
| OACGODDC_1 | 967583 | 968275 | STU_RS14640 | 0.0 | Capsule | Immune modulation | 99.86 | 100.00 | WP_011226047 |
| OACGODDC_1 | 1079571 | 1080164 | STER_RS06030 | 0.0 | Capsule | Immune modulation | 99.83 | 100.00 | WP_011226149 |
| OACGODDC_1 | 1079571 | 1080164 | STU_RS15260 | 0.0 | Capsule | Immune modulation | 99.83 | 100.00 | WP_011226149 |
| OACGODDC_1 | 1292408 | 1293667 | STER_RS07100 | 0.0 | Capsule | Immune modulation | 99.76 | 100.00 | WP_011681445 |
| OACGODDC_1 | 43553 | 44392 | cbpD | 0.0 | Autolysin | Exoenzyme | 99.64 | 100.00 | WP_011226733 |
| OACGODDC_1 | 1290449 | 1291417 | STER_RS07090 | 0.0 | Capsule | Immune modulation | 99.59 | 100.00 | WP_011681443 |
| OACGODDC_1 | 843264 | 844922 | fbp54 | 0.0 | FBPs | Adherence | 99.52 | 100.00 | WP_011227179 |
| OACGODDC_1 | 1291435 | 1292411 | STER_RS07095 | 0.0 | Capsule | Immune modulation | 99.49 | 99.90 | WP_011681444 |
| OACGODDC_1 | 967583 | 968275 | STR_RS05255 | 0.0 | Capsule | Immune modulation | 99.28 | 100.00 | WP_011227247 |
| OACGODDC_1 | 1080164 | 1081033 | rfbA | 0.0 | Capsule | Immune modulation | 99.19 | 100.00 | WP_011681286 |
| OACGODDC_1 | 968284 | 969015 | STER_RS05315 | 0.0 | Capsule | Immune modulation | 99.18 | 100.00 | WP_011681176 |
| OACGODDC_1 | 1034753 | 1035543 | cshA | 0.0 | Cell surface hydrophobicity proteins | Adherence | 99.11 | 100.00 | - |
| OACGODDC_1 | 1114933 | 1115694 | srtA | 0.0 | Sortase A | Exoenzyme | 99.08 | 100.00 | - |
| OACGODDC_1 | 968284 | 969015 | STU_RS14645 | 0.0 | Capsule | Immune modulation | 98.63 | 100.00 | WP_011226048 |
| OACGODDC_1 | 968284 | 969015 | STR_RS05260 | 0.0 | Capsule | Immune modulation | 98.50 | 100.00 | WP_011227248 |
| OACGODDC_1 | 1289732 | 1290447 | STER_RS07085 | 0.0 | Capsule | Immune modulation | 98.18 | 99.86 | WP_011681442 |
| OACGODDC_1 | 1288616 | 1289386 | STER_RS07075 | 0.0 | Capsule | Immune modulation | 97.92 | 99.23 | WP_011681440 |
| OACGODDC_1 | 969016 | 970476 | STER_RS05320 | 0.0 | Capsule | Immune modulation | 97.88 | 100.00 | WP_011681177 |
| OACGODDC_1 | 969016 | 970476 | STU_RS14650 | 0.0 | Capsule | Immune modulation | 96.99 | 100.21 | WP_011226049 |
| OACGODDC_1 | 965408 | 966773 | STER_RS05300 | 0.0 | Capsule | Immune modulation | 96.41 | 99.85 | WP_011681173 |
| OACGODDC_1 | 1293786 | 1294637 | rfbD | 0.0 | Capsule | Immune modulation | 96.36 | 100.00 | WP_014621820 |
| OACGODDC_1 | 969016 | 970476 | STR_RS05265 | 0.0 | Capsule | Immune modulation | 96.17 | 100.21 | WP_041827043 |
| OACGODDC_1 | 966830 | 967573 | STER_RS05305 | 0.0 | Capsule | Immune modulation | 95.70 | 100.13 | WP_011681174 |
| OACGODDC_1 | 966830 | 967573 | STU_RS14635 | 0.0 | Capsule | Immune modulation | 95.56 | 100.13 | WP_011226046 |
| OACGODDC_1 | 966835 | 967573 | STR_RS05250 | 0.0 | Capsule | Immune modulation | 94.72 | 98.27 | WP_011227246 |
| OACGODDC_1 | 965406 | 966773 | STU_RS14630 | 0.0 | Capsule | Immune modulation | 93.28 | 100.00 | WP_011226045 |
| OACGODDC_1 | 967583 | 968275 | STER_RS05310 | 0.0 | Capsule | Immune modulation | 89.75 | 100.00 | WP_011681175 |
| OACGODDC_1 | 593451 | 594754 | eno | 0.0 | Streptococcal enolase | Exoenzyme | 88.17 | 99.54 | WP_000022832 |
| OACGODDC_1 | 1568802 | 1569812 | plr/gapA | 0.0 | Streptococcal plasmin receptor/GAPDH | Adherence | 86.92 | 99.51 | WP_002986042 |
| OACGODDC_1 | 146968 | 148251 | tig/ropA | 0.0 | Trigger factor | Stress survival | 80.58 | 99.77 | WP_000107753 |
| OACGODDC_1 | 1078096 | 1079142 | rfbB | 0.0 | Capsule | Immune modulation | 80.42 | 100.00 | WP_009659423 |
| OACGODDC_1 | 957246 | 957829 | SPD_RS01775 | 2.26e-143 | Capsule | Immune modulation | 82.73 | 96.20 | WP_001819836 |
BLASTN v2.16.0 (Database: VFDB, Dec. 2024 release)
VirulenceFinder
| Query ID | Begin | End | Database | Virulence factor | Protein function | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
VirulenceFinder v2.0. 4 (Database: virulencefinder_db, Feb . 2024 release)
Pathogenic genes
PHI-base
| Query ID | qstart | qend | Gene name | e-value | Function | Identity | Coverage | Gene ID |
|---|---|---|---|---|---|---|---|---|
| OACGODDC_1 | 1118381 | 1119364 | ldh(Sp_1220) | 0.0 | L-lactate dehydrogenase | 94.82 | 100.00 | AAK75326 |
| OACGODDC_1 | 694066 | 695139 | MntE | 0.0 | manganese homeostasis | 94.41 | 99.72 | ABF32167 |
| OACGODDC_1 | 511202 | 512170 | spr0084 | 0.0 | pathogenitcity related | 93.19 | 98.48 | AAK98888 |
| OACGODDC_1 | 1450999 | 1453302 | pfl2(Sp_0459) | 0.0 | formate acetyltransferase | 93.10 | 99.22 | AAK74619 |
| OACGODDC_1 | 724218 | 726464 | metE | 0.0 | methionine biosynthesis enzymes | 91.99 | 100.00 | AAK74738 |
| OACGODDC_1 | 1192876 | 1194357 | SPD_0310 | 0.0 | UPF0371 protein SPD_0310 | 91.90 | 100.00 | ABJ54480 |
| OACGODDC_1 | 64055 | 65047 | recA | 0.0 | DNA recombination and repair | 91.24 | 85.31 | AAL00560 |
| OACGODDC_1 | 27072 | 28043 | prsA2 | 0.0 | ribose-phosphate pyrophosphokinase | 90.12 | 100.00 | ABF36968 |
| OACGODDC_1 | 1335721 | 1334570 | potA | 0.0 | ABC transporter ATP-binding protein-spermidine/putrescine transport | 89.06 | 99.74 | AAL00050 |
| OACGODDC_1 | 1307706 | 1305718 | uvrB | 0.0 | excinuclease ABC, B subunit | 88.99 | 100.00 | AE014259_2 |
| OACGODDC_1 | 1102185 | 1100455 | ptsI | 0.0 | phosphoenolpyruvate-protein phosphotransferase | 87.69 | 100.00 | AAK34199 |
| OACGODDC_1 | 1761415 | 1759937 | IMPDH | 0.0 | inosine-5'-monophosphate dehydrogenase | 87.22 | 100.00 | ADE32434 |
| OACGODDC_1 | 593451 | 594752 | Eno | 0.0 | enolase | 86.21 | 99.77 | ABP90468 |
| OACGODDC_1 | 1746219 | 1744327 | gidA | 0.0 | tRNA uridine 5-carboxymethylaminomethyl modification enzyme | 86.05 | 98.90 | ABP91129 |
| OACGODDC_1 | 729389 | 727680 | PGM | 0.0 | phosphoglucomutase | 83.89 | 99.65 | ACH87041 |
| OACGODDC_1 | 1612914 | 1613924 | pdh | 0.0 | pyruvate dehydrogenase | 83.09 | 99.70 | ABP91006 |
| OACGODDC_1 | 869110 | 867749 | mnmE | 0.0 | central tRNA-modifying GTPase | 82.24 | 99.56 | ABP90420 |
| OACGODDC_1 | 1664655 | 1662763 | PepO | 0.0 | endopeptidase | 80.03 | 100.00 | ABF32980 |
| OACGODDC_1 | 579021 | 579911 | bglB | 1.27e-178 | putative phospho--glucosidase | 88.89 | 99.66 | AAK33487 |
| OACGODDC_1 | 788767 | 787829 | SP_0676 | 7.86e-168 | transcription facot | 81.47 | 97.20 | AAK74821 |
| OACGODDC_1 | 726656 | 727513 | metF | 8.27e-165 | methionine biosynthesis enzymes | 86.36 | 99.31 | AAK74739 |
| OACGODDC_1 | 1007168 | 1006464 | covR | 1.02e-130 | responder protein | 85.11 | 100.00 | AAK71319 |
| OACGODDC_1 | 1164785 | 1164114 | rr01 | 2.82e-125 | response regulator | 84.38 | 99.56 | CAB54566 |
| OACGODDC_1 | 1007168 | 1006464 | walR | 5.11e-121 | DNA-binding response regulator | 81.28 | 100.00 | ANC99504 |
| OACGODDC_1 | 297562 | 298248 | CovR | 9.62e-118 | serves to repress GAS virulence factor-encoding genes | 80.79 | 100.00 | ACE75886 |
| OACGODDC_1 | 733343 | 734011 | CiaR | 1.93e-117 | two-component response regulator | 84.31 | 99.55 | AAK74935 |
| OACGODDC_1 | 733343 | 734014 | ciaR | 1.90e-115 | two component system response regulator | 82.14 | 99.12 | AIK75708 |
| OACGODDC_1 | 65344 | 65739 | SpxA2 | 3.54e-74 | transcriptional regulator | 90.91 | 100.00 | ERL21461 |
| OACGODDC_1 | 148409 | 148909 | RopE (M5005_Spy_1611) | 4.71e-75 | probable DNA-directed RNA polymerase subunit delta | 81.44 | 87.43 | AAK34603 |
| OACGODDC_1 | 1450999 | 1453296 | PFL (B9H01_RS01125) | 0.0 | formate C-acetyltransferase | 83.07 | 98.08 | MYN69560 |
| OACGODDC_1 | 1650196 | 1649177 | ilvC (SPD_0406) | 0.0 | ketol-acid reductoisomerase (NADP(+)) | 96.47 | 100.00 | ABJ55451 |
BLASTX v2.16.0 (Database: PHI base v4.16, May. 2024 release)
Plasmid
PlasmidFinder
| Query ID | Begin | End | Plasmid | Query / Template | Identity | Accession no. |
|---|---|---|---|---|---|---|
| No hit found | ||||||
PlasmidFinder v 2.1.6 (Database: plasmidfinder_db v 2.2.0 , Nov. 2024 release)
PlasmidHunter
| Query ID | Prediction | Chromosome | Plasmid |
|---|---|---|---|
| OACGODDC_1 | 0.0 | 1.0 | 0.0 |
PlasmidHunter v 1.4.5 (Database: May. 2024 release)
Prophage
Phigaro
| Query ID | Begin | End | Transposable | Taxonomy | pVOGs |
|---|---|---|---|---|---|
| No hit found | |||||
Phigaro v2.4.0 (Database: Jan. 2024 release)