Probiotic potential risk score
| ARGs | VFs | PGs | PPRS |
|---|---|---|---|
| 0 | 26 | 29 | 38.95 |
PPRS is classified as low-risk (≤4), medium-risk (4-6), and high-risk (≥6).
Antibiotic resistance genes
Comprehensive Antibiotic Resistance Database (CARD)
| Query ID | Begin | End | ARO name | ARO accession | CARD name | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
RGI v6.0.3 (Database: CARD Variants v4.0.2, Nov. 2023 release)
ResFinder
| Query ID | Begin | End | Resistance gene | Phenotype | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|
| No hit found | |||||||
ResFinder v4.6.0 (Database: resfinder_db, Aug. 2024 release)
AMRFinderPlus
| Query ID | Begin | End | Gene symbol | Sequence name | Method | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
AMRFinderPlus v4.0.3 (Database: Oct. 2024 release)
Virulence factors
Virulence Factor Database (VFDB)
| Query ID | qstart | qend | Gene name | e-value | VF name | VF category | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|---|
| NGILHAAC_1 | 43634 | 44473 | cbpD | 0.0 | Autolysin | Exoenzyme | 100.00 | 100.00 | WP_011226733 |
| NGILHAAC_1 | 1091646 | 1092239 | STR_RS05880 | 0.0 | Capsule | Immune modulation | 99.83 | 100.00 | WP_011226149 |
| NGILHAAC_1 | 1288442 | 1289398 | STU_RS16250 | 0.0 | Capsule | Immune modulation | 99.79 | 100.00 | WP_011226328 |
| NGILHAAC_1 | 1287649 | 1288458 | STU_RS16245 | 0.0 | Capsule | Immune modulation | 99.75 | 100.00 | WP_002948020 |
| NGILHAAC_1 | 1091646 | 1092239 | STER_RS06030 | 0.0 | Capsule | Immune modulation | 99.66 | 100.00 | WP_011226149 |
| NGILHAAC_1 | 1091646 | 1092239 | STU_RS15260 | 0.0 | Capsule | Immune modulation | 99.66 | 100.00 | WP_011226149 |
| NGILHAAC_1 | 1289395 | 1290543 | STU_RS16255 | 0.0 | Capsule | Immune modulation | 99.65 | 100.00 | WP_041828290 |
| NGILHAAC_1 | 1294039 | 1294890 | rfbD | 0.0 | Capsule | Immune modulation | 99.53 | 100.00 | WP_014621820 |
| NGILHAAC_1 | 1285369 | 1286424 | STU_RS16235 | 0.0 | Capsule | Immune modulation | 99.53 | 100.00 | WP_002948022 |
| NGILHAAC_1 | 844656 | 846314 | fbp54 | 0.0 | FBPs | Adherence | 99.52 | 100.00 | WP_011227179 |
| NGILHAAC_1 | 1286444 | 1287649 | STU_RS16240 | 0.0 | Capsule | Immune modulation | 99.50 | 100.00 | WP_011226326 |
| NGILHAAC_1 | 1283588 | 1285372 | STU_RS16230 | 0.0 | Capsule | Immune modulation | 99.44 | 100.00 | WP_011226325 |
| NGILHAAC_1 | 978404 | 979003 | STR_RS05245 | 0.0 | Capsule | Immune modulation | 99.33 | 100.00 | WP_196767671 |
| NGILHAAC_1 | 1092239 | 1093108 | rfbA | 0.0 | Capsule | Immune modulation | 99.08 | 100.00 | WP_011681286 |
| NGILHAAC_1 | 957226 | 958641 | STER_RS05250 | 0.0 | Capsule | Immune modulation | 99.01 | 100.00 | WP_011681165 |
| NGILHAAC_1 | 1047120 | 1047910 | cshA | 0.0 | Cell surface hydrophobicity proteins | Adherence | 98.99 | 100.00 | - |
| NGILHAAC_1 | 1290652 | 1291662 | STU_RS16260 | 0.0 | Capsule | Immune modulation | 98.91 | 100.00 | WP_011226330 |
| NGILHAAC_1 | 1127003 | 1127764 | srtA | 0.0 | Sortase A | Exoenzyme | 98.82 | 100.00 | - |
| NGILHAAC_1 | 981339 | 982793 | STU_RS14650 | 0.0 | Capsule | Immune modulation | 98.76 | 100.00 | WP_011226049 |
| NGILHAAC_1 | 981339 | 982793 | STR_RS05265 | 0.0 | Capsule | Immune modulation | 98.62 | 100.00 | WP_041827043 |
| NGILHAAC_1 | 977280 | 978239 | STR_RS05240 | 0.0 | Capsule | Immune modulation | 98.23 | 100.00 | WP_041827042 |
| NGILHAAC_1 | 1291662 | 1292936 | STU_RS16265 | 0.0 | Capsule | Immune modulation | 98.20 | 100.00 | WP_011226331 |
| NGILHAAC_1 | 979155 | 979890 | STER_RS05305 | 0.0 | Capsule | Immune modulation | 97.96 | 99.33 | WP_011681174 |
| NGILHAAC_1 | 979155 | 979890 | STU_RS14635 | 0.0 | Capsule | Immune modulation | 97.83 | 99.33 | WP_011226046 |
| NGILHAAC_1 | 980607 | 981338 | STER_RS05315 | 0.0 | Capsule | Immune modulation | 97.68 | 100.00 | WP_011681176 |
| NGILHAAC_1 | 979141 | 979890 | STR_RS05250 | 0.0 | Capsule | Immune modulation | 97.47 | 100.00 | WP_011227246 |
| NGILHAAC_1 | 980607 | 981338 | STU_RS14645 | 0.0 | Capsule | Immune modulation | 97.27 | 100.00 | WP_011226048 |
| NGILHAAC_1 | 981339 | 982793 | STER_RS05320 | 0.0 | Capsule | Immune modulation | 97.06 | 99.79 | WP_011681177 |
| NGILHAAC_1 | 980607 | 981338 | STR_RS05260 | 0.0 | Capsule | Immune modulation | 96.86 | 100.00 | WP_011227248 |
| NGILHAAC_1 | 979900 | 980581 | STU_RS14640 | 0.0 | Capsule | Immune modulation | 93.25 | 98.41 | WP_011226047 |
| NGILHAAC_1 | 979900 | 980581 | STR_RS05255 | 0.0 | Capsule | Immune modulation | 92.96 | 98.41 | WP_011227247 |
| NGILHAAC_1 | 596279 | 597582 | eno | 0.0 | Streptococcal enolase | Exoenzyme | 87.86 | 99.54 | WP_000022832 |
| NGILHAAC_1 | 1578498 | 1579508 | plr/gapA | 0.0 | Streptococcal plasmin receptor/GAPDH | Adherence | 86.92 | 99.51 | WP_002986042 |
| NGILHAAC_1 | 979900 | 980581 | STER_RS05310 | 0.0 | Capsule | Immune modulation | 85.92 | 98.41 | WP_011681175 |
| NGILHAAC_1 | 140673 | 141956 | tig/ropA | 0.0 | Trigger factor | Stress survival | 80.58 | 99.77 | WP_000107753 |
| NGILHAAC_1 | 1090171 | 1091217 | rfbB | 0.0 | Capsule | Immune modulation | 80.33 | 100.00 | WP_009659423 |
BLASTN v2.16.0 (Database: VFDB, Dec. 2024 release)
VirulenceFinder
| Query ID | Begin | End | Database | Virulence factor | Protein function | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
VirulenceFinder v2.0. 4 (Database: virulencefinder_db, Feb . 2024 release)
Pathogenic genes
PHI-base
| Query ID | qstart | qend | Gene name | e-value | Function | Identity | Coverage | Gene ID |
|---|---|---|---|---|---|---|---|---|
| NGILHAAC_1 | 1130451 | 1131434 | ldh(Sp_1220) | 0.0 | L-lactate dehydrogenase | 94.82 | 100.00 | AAK75326 |
| NGILHAAC_1 | 698238 | 699311 | MntE | 0.0 | manganese homeostasis | 94.41 | 99.72 | ABF32167 |
| NGILHAAC_1 | 1457828 | 1460131 | pfl2(Sp_0459) | 0.0 | formate acetyltransferase | 93.10 | 99.22 | AAK74619 |
| NGILHAAC_1 | 514070 | 515038 | spr0084 | 0.0 | pathogenitcity related | 92.57 | 98.48 | AAK98888 |
| NGILHAAC_1 | 1202574 | 1204055 | SPD_0310 | 0.0 | UPF0371 protein SPD_0310 | 92.11 | 100.00 | ABJ54480 |
| NGILHAAC_1 | 726487 | 728733 | metE | 0.0 | methionine biosynthesis enzymes | 91.99 | 100.00 | AAK74738 |
| NGILHAAC_1 | 64579 | 65577 | recA | 0.0 | DNA recombination and repair | 91.29 | 85.82 | AAL00560 |
| NGILHAAC_1 | 27153 | 28124 | prsA2 | 0.0 | ribose-phosphate pyrophosphokinase | 90.12 | 100.00 | ABF36968 |
| NGILHAAC_1 | 1337866 | 1336715 | potA | 0.0 | ABC transporter ATP-binding protein-spermidine/putrescine transport | 89.32 | 99.74 | AAL00050 |
| NGILHAAC_1 | 1309860 | 1307872 | uvrB | 0.0 | excinuclease ABC, B subunit | 88.99 | 100.00 | AE014259_2 |
| NGILHAAC_1 | 1114256 | 1112526 | ptsI | 0.0 | phosphoenolpyruvate-protein phosphotransferase | 87.69 | 100.00 | AAK34199 |
| NGILHAAC_1 | 1803820 | 1802342 | IMPDH | 0.0 | inosine-5'-monophosphate dehydrogenase | 87.63 | 100.00 | ADE32434 |
| NGILHAAC_1 | 596279 | 597580 | Eno | 0.0 | enolase | 86.21 | 99.77 | ABP90468 |
| NGILHAAC_1 | 1788625 | 1786733 | gidA | 0.0 | tRNA uridine 5-carboxymethylaminomethyl modification enzyme | 86.05 | 98.90 | ABP91129 |
| NGILHAAC_1 | 731659 | 729950 | PGM | 0.0 | phosphoglucomutase | 83.89 | 99.65 | ACH87041 |
| NGILHAAC_1 | 1622156 | 1623166 | pdh | 0.0 | pyruvate dehydrogenase | 83.09 | 99.70 | ABP91006 |
| NGILHAAC_1 | 873008 | 871647 | mnmE | 0.0 | central tRNA-modifying GTPase | 82.02 | 99.56 | ABP90420 |
| NGILHAAC_1 | 1672423 | 1670531 | PepO | 0.0 | endopeptidase | 80.03 | 100.00 | ABF32980 |
| NGILHAAC_1 | 581847 | 582737 | bglB | 2.85e-178 | putative phospho--glucosidase | 88.55 | 99.66 | AAK33487 |
| NGILHAAC_1 | 791004 | 790066 | SP_0676 | 8.05e-168 | transcription facot | 81.47 | 97.20 | AAK74821 |
| NGILHAAC_1 | 728925 | 729782 | metF | 1.47e-164 | methionine biosynthesis enzymes | 86.01 | 99.31 | AAK74739 |
| NGILHAAC_1 | 1019488 | 1018784 | covR | 4.77e-131 | responder protein | 85.53 | 100.00 | AAK71319 |
| NGILHAAC_1 | 1183604 | 1182933 | rr01 | 5.41e-125 | response regulator | 84.38 | 99.56 | CAB54566 |
| NGILHAAC_1 | 1019488 | 1018784 | walR | 2.21e-121 | DNA-binding response regulator | 81.70 | 100.00 | ANC99504 |
| NGILHAAC_1 | 735613 | 736281 | CiaR | 3.86e-120 | two-component response regulator | 85.65 | 99.55 | AAK74935 |
| NGILHAAC_1 | 735613 | 736284 | ciaR | 5.49e-118 | two component system response regulator | 83.48 | 99.12 | AIK75708 |
| NGILHAAC_1 | 289591 | 290277 | CovR | 3.93e-117 | serves to repress GAS virulence factor-encoding genes | 80.35 | 100.00 | ACE75886 |
| NGILHAAC_1 | 65853 | 66227 | SpxA2 | 1.13e-69 | transcriptional regulator | 91.20 | 94.70 | ERL21461 |
| NGILHAAC_1 | 884365 | 884766 | SpxA1 | 3.68e-66 | transcriptional regulator | 80.60 | 100.00 | ERL19273 |
| NGILHAAC_1 | 142114 | 142614 | RopE (M5005_Spy_1611) | 4.82e-75 | probable DNA-directed RNA polymerase subunit delta | 81.44 | 87.43 | AAK34603 |
| NGILHAAC_1 | 1457828 | 1460125 | PFL (B9H01_RS01125) | 0.0 | formate C-acetyltransferase | 83.07 | 98.08 | MYN69560 |
| NGILHAAC_1 | 1658023 | 1657004 | ilvC (SPD_0406) | 0.0 | ketol-acid reductoisomerase (NADP(+)) | 96.47 | 100.00 | ABJ55451 |
BLASTX v2.16.0 (Database: PHI base v4.16, May. 2024 release)
Plasmid
PlasmidFinder
| Query ID | Begin | End | Plasmid | Query / Template | Identity | Accession no. |
|---|---|---|---|---|---|---|
| No hit found | ||||||
PlasmidFinder v 2.1.6 (Database: plasmidfinder_db v 2.2.0 , Nov. 2024 release)
PlasmidHunter
| Query ID | Prediction | Chromosome | Plasmid |
|---|---|---|---|
| NGILHAAC_1 | 0.0 | 1.0 | 0.0 |
PlasmidHunter v 1.4.5 (Database: May. 2024 release)
Prophage
Phigaro
| Query ID | Begin | End | Transposable | Taxonomy | pVOGs |
|---|---|---|---|---|---|
| No hit found | |||||
Phigaro v2.4.0 (Database: Jan. 2024 release)