Probiotic potential risk score
| ARGs | VFs | PGs | PPRS |
|---|---|---|---|
| 0 | 25 | 28 | 37.54 |
PPRS is classified as low-risk (≤4), medium-risk (4-6), and high-risk (≥6).
Antibiotic resistance genes
Comprehensive Antibiotic Resistance Database (CARD)
| Query ID | Begin | End | ARO name | ARO accession | CARD name | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
RGI v6.0.3 (Database: CARD Variants v4.0.2, Nov. 2023 release)
ResFinder
| Query ID | Begin | End | Resistance gene | Phenotype | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|
| No hit found | |||||||
ResFinder v4.6.0 (Database: resfinder_db, Aug. 2024 release)
AMRFinderPlus
| Query ID | Begin | End | Gene symbol | Sequence name | Method | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
AMRFinderPlus v4.0.3 (Database: Oct. 2024 release)
Virulence factors
Virulence Factor Database (VFDB)
| Query ID | qstart | qend | Gene name | e-value | VF name | VF category | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|---|
| FFLPICFJ_1 | 1131335 | 1132204 | rfbA | 0.0 | Capsule | Immune modulation | 100.00 | 100.00 | WP_011681286 |
| FFLPICFJ_1 | 1130742 | 1131335 | STER_RS06030 | 0.0 | Capsule | Immune modulation | 100.00 | 100.00 | WP_011226149 |
| FFLPICFJ_1 | 1348244 | 1349053 | STU_RS16245 | 0.0 | Capsule | Immune modulation | 99.88 | 100.00 | WP_002948020 |
| FFLPICFJ_1 | 1130742 | 1131335 | STR_RS05880 | 0.0 | Capsule | Immune modulation | 99.83 | 100.00 | WP_011226149 |
| FFLPICFJ_1 | 1349037 | 1349993 | STU_RS16250 | 0.0 | Capsule | Immune modulation | 99.79 | 100.00 | WP_011226328 |
| FFLPICFJ_1 | 1349990 | 1351138 | STU_RS16255 | 0.0 | Capsule | Immune modulation | 99.74 | 100.00 | WP_041828290 |
| FFLPICFJ_1 | 1130742 | 1131335 | STU_RS15260 | 0.0 | Capsule | Immune modulation | 99.66 | 100.00 | WP_011226149 |
| FFLPICFJ_1 | 1354634 | 1355485 | rfbD | 0.0 | Capsule | Immune modulation | 99.65 | 100.00 | WP_014621820 |
| FFLPICFJ_1 | 921488 | 923146 | fbp54 | 0.0 | FBPs | Adherence | 99.58 | 100.00 | WP_011227179 |
| FFLPICFJ_1 | 1347039 | 1348244 | STU_RS16240 | 0.0 | Capsule | Immune modulation | 99.58 | 100.00 | WP_011226326 |
| FFLPICFJ_1 | 1344183 | 1345967 | STU_RS16230 | 0.0 | Capsule | Immune modulation | 99.50 | 100.00 | WP_011226325 |
| FFLPICFJ_1 | 1351247 | 1352257 | STU_RS16260 | 0.0 | Capsule | Immune modulation | 99.50 | 100.00 | WP_011226330 |
| FFLPICFJ_1 | 1345964 | 1347019 | STU_RS16235 | 0.0 | Capsule | Immune modulation | 99.34 | 100.00 | WP_002948022 |
| FFLPICFJ_1 | 827450 | 828865 | STER_RS05250 | 0.0 | Capsule | Immune modulation | 99.15 | 100.00 | WP_011681165 |
| FFLPICFJ_1 | 1167525 | 1168286 | srtA | 0.0 | Sortase A | Exoenzyme | 98.82 | 100.00 | - |
| FFLPICFJ_1 | 43634 | 44473 | cbpD | 0.0 | Autolysin | Exoenzyme | 98.69 | 100.00 | WP_011226733 |
| FFLPICFJ_1 | 1070326 | 1071114 | cshA | 0.0 | Cell surface hydrophobicity proteins | Adherence | 98.48 | 99.75 | - |
| FFLPICFJ_1 | 802544 | 803275 | STU_RS14645 | 0.0 | Capsule | Immune modulation | 98.36 | 100.00 | WP_011226048 |
| FFLPICFJ_1 | 802544 | 803275 | STER_RS05315 | 0.0 | Capsule | Immune modulation | 98.09 | 100.00 | WP_011681176 |
| FFLPICFJ_1 | 802544 | 803275 | STR_RS05260 | 0.0 | Capsule | Immune modulation | 97.68 | 100.00 | WP_011227248 |
| FFLPICFJ_1 | 1352260 | 1353531 | STU_RS16265 | 0.0 | Capsule | Immune modulation | 97.48 | 99.76 | WP_011226331 |
| FFLPICFJ_1 | 801083 | 802543 | STER_RS05320 | 0.0 | Capsule | Immune modulation | 97.06 | 100.00 | WP_011681177 |
| FFLPICFJ_1 | 803986 | 804726 | STER_RS05305 | 0.0 | Capsule | Immune modulation | 97.03 | 100.00 | WP_011681174 |
| FFLPICFJ_1 | 803986 | 804726 | STU_RS14635 | 0.0 | Capsule | Immune modulation | 96.36 | 100.00 | WP_011226046 |
| FFLPICFJ_1 | 801083 | 802543 | STU_RS14650 | 0.0 | Capsule | Immune modulation | 96.30 | 100.21 | WP_011226049 |
| FFLPICFJ_1 | 801083 | 802543 | STR_RS05265 | 0.0 | Capsule | Immune modulation | 96.17 | 100.21 | WP_041827043 |
| FFLPICFJ_1 | 803986 | 804721 | STR_RS05250 | 0.0 | Capsule | Immune modulation | 96.06 | 98.13 | WP_011227246 |
| FFLPICFJ_1 | 804783 | 806146 | STU_RS14630 | 0.0 | Capsule | Immune modulation | 95.53 | 99.71 | WP_011226045 |
| FFLPICFJ_1 | 803284 | 803976 | STR_RS05255 | 0.0 | Capsule | Immune modulation | 95.40 | 99.86 | WP_011227247 |
| FFLPICFJ_1 | 803284 | 803976 | STU_RS14640 | 0.0 | Capsule | Immune modulation | 95.40 | 99.86 | WP_011226047 |
| FFLPICFJ_1 | 804783 | 806150 | STER_RS05300 | 0.0 | Capsule | Immune modulation | 94.52 | 99.93 | WP_011681173 |
| FFLPICFJ_1 | 803284 | 803976 | STER_RS05310 | 0.0 | Capsule | Immune modulation | 89.47 | 100.00 | WP_011681175 |
| FFLPICFJ_1 | 606688 | 607991 | eno | 0.0 | Streptococcal enolase | Exoenzyme | 88.10 | 99.46 | WP_000022832 |
| FFLPICFJ_1 | 1642467 | 1643477 | plr/gapA | 0.0 | Streptococcal plasmin receptor/GAPDH | Adherence | 87.46 | 99.80 | WP_002986042 |
| FFLPICFJ_1 | 148008 | 149291 | tig/ropA | 0.0 | Trigger factor | Stress survival | 80.73 | 99.77 | WP_000107753 |
| FFLPICFJ_1 | 1129267 | 1130313 | rfbB | 0.0 | Capsule | Immune modulation | 80.61 | 100.00 | WP_009659423 |
BLASTN v2.16.0 (Database: VFDB, Dec. 2024 release)
VirulenceFinder
| Query ID | Begin | End | Database | Virulence factor | Protein function | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
VirulenceFinder v2.0. 4 (Database: virulencefinder_db, Feb . 2024 release)
Pathogenic genes
PHI-base
| Query ID | qstart | qend | Gene name | e-value | Function | Identity | Coverage | Gene ID |
|---|---|---|---|---|---|---|---|---|
| FFLPICFJ_1 | 1170973 | 1171956 | ldh(Sp_1220) | 0.0 | L-lactate dehydrogenase | 94.82 | 100.00 | AAK75326 |
| FFLPICFJ_1 | 716231 | 717304 | MntE | 0.0 | manganese homeostasis | 94.41 | 99.72 | ABF32167 |
| FFLPICFJ_1 | 1520452 | 1522755 | pfl2(Sp_0459) | 0.0 | formate acetyltransferase | 92.97 | 99.22 | AAK74619 |
| FFLPICFJ_1 | 523053 | 524021 | spr0084 | 0.0 | pathogenitcity related | 92.57 | 98.48 | AAK98888 |
| FFLPICFJ_1 | 1245634 | 1247115 | SPD_0310 | 0.0 | UPF0371 protein SPD_0310 | 92.31 | 100.00 | ABJ54480 |
| FFLPICFJ_1 | 744609 | 746855 | metE | 0.0 | methionine biosynthesis enzymes | 91.99 | 100.00 | AAK74738 |
| FFLPICFJ_1 | 63264 | 64256 | recA | 0.0 | DNA recombination and repair | 91.24 | 85.31 | AAL00560 |
| FFLPICFJ_1 | 27148 | 28119 | prsA2 | 0.0 | ribose-phosphate pyrophosphokinase | 90.12 | 100.00 | ABF36968 |
| FFLPICFJ_1 | 1406759 | 1405608 | potA | 0.0 | ABC transporter ATP-binding protein-spermidine/putrescine transport | 89.32 | 99.74 | AAL00050 |
| FFLPICFJ_1 | 1370455 | 1368467 | uvrB | 0.0 | excinuclease ABC, B subunit | 88.84 | 100.00 | AE014259_2 |
| FFLPICFJ_1 | 1154778 | 1153048 | ptsI | 0.0 | phosphoenolpyruvate-protein phosphotransferase | 88.04 | 100.00 | AAK34199 |
| FFLPICFJ_1 | 1846497 | 1845019 | IMPDH | 0.0 | inosine-5'-monophosphate dehydrogenase | 87.42 | 100.00 | ADE32434 |
| FFLPICFJ_1 | 606688 | 607989 | Eno | 0.0 | enolase | 86.21 | 99.77 | ABP90468 |
| FFLPICFJ_1 | 1046692 | 1048401 | PGM | 0.0 | phosphoglucomutase | 84.06 | 99.65 | ACH87041 |
| FFLPICFJ_1 | 1685759 | 1686769 | pdh | 0.0 | pyruvate dehydrogenase | 83.09 | 99.70 | ABP91006 |
| FFLPICFJ_1 | 893593 | 894954 | mnmE | 0.0 | central tRNA-modifying GTPase | 82.24 | 99.56 | ABP90420 |
| FFLPICFJ_1 | 1736126 | 1734234 | PepO | 0.0 | endopeptidase | 80.19 | 100.00 | ABF32980 |
| FFLPICFJ_1 | 592252 | 593142 | bglB | 5.27e-178 | putative phospho--glucosidase | 88.55 | 99.66 | AAK33487 |
| FFLPICFJ_1 | 976951 | 977886 | SP_0676 | 7.40e-168 | transcription facot | 81.73 | 96.89 | AAK74821 |
| FFLPICFJ_1 | 747047 | 747904 | metF | 1.53e-164 | methionine biosynthesis enzymes | 86.36 | 99.31 | AAK74739 |
| FFLPICFJ_1 | 764228 | 764932 | covR | 4.39e-131 | responder protein | 85.53 | 100.00 | AAK71319 |
| FFLPICFJ_1 | 1226659 | 1225988 | rr01 | 3.01e-124 | response regulator | 83.93 | 99.56 | CAB54566 |
| FFLPICFJ_1 | 764228 | 764932 | walR | 1.85e-121 | DNA-binding response regulator | 82.13 | 100.00 | ANC99504 |
| FFLPICFJ_1 | 303688 | 304374 | CovR | 1.03e-117 | serves to repress GAS virulence factor-encoding genes | 80.79 | 100.00 | ACE75886 |
| FFLPICFJ_1 | 1042738 | 1042070 | CiaR | 2.03e-117 | two-component response regulator | 84.31 | 99.55 | AAK74935 |
| FFLPICFJ_1 | 1042738 | 1042067 | ciaR | 1.99e-115 | two component system response regulator | 82.14 | 99.12 | AIK75708 |
| FFLPICFJ_1 | 64553 | 64948 | SpxA2 | 3.71e-74 | transcriptional regulator | 90.91 | 100.00 | ERL21461 |
| FFLPICFJ_1 | 882230 | 881829 | SpxA1 | 3.77e-66 | transcriptional regulator | 80.60 | 100.00 | ERL19273 |
| FFLPICFJ_1 | 149449 | 149949 | RopE (M5005_Spy_1611) | 4.93e-75 | probable DNA-directed RNA polymerase subunit delta | 81.44 | 87.43 | AAK34603 |
| FFLPICFJ_1 | 1520452 | 1522749 | PFL (B9H01_RS01125) | 0.0 | formate C-acetyltransferase | 82.94 | 98.08 | MYN69560 |
| FFLPICFJ_1 | 1721670 | 1720651 | ilvC (SPD_0406) | 0.0 | ketol-acid reductoisomerase (NADP(+)) | 96.47 | 100.00 | ABJ55451 |
| FFLPICFJ_1 | 1830623 | 1829415 | gidA | 0.0 | tRNA uridine 5-carboxymethylaminomethyl modification enzyme | 84.61 | 63.17 | ABP91129 |
BLASTX v2.16.0 (Database: PHI base v4.16, May. 2024 release)
Plasmid
PlasmidFinder
| Query ID | Begin | End | Plasmid | Query / Template | Identity | Accession no. |
|---|---|---|---|---|---|---|
| No hit found | ||||||
PlasmidFinder v 2.1.6 (Database: plasmidfinder_db v 2.2.0 , Nov. 2024 release)
PlasmidHunter
| Query ID | Prediction | Chromosome | Plasmid |
|---|---|---|---|
| FFLPICFJ_1 | 0.0 | 1.0 | 0.0 |
PlasmidHunter v 1.4.5 (Database: May. 2024 release)
Prophage
Phigaro
| Query ID | Begin | End | Transposable | Taxonomy | pVOGs |
|---|---|---|---|---|---|
| No hit found | |||||
Phigaro v2.4.0 (Database: Jan. 2024 release)