Probiotic potential risk score
| ARGs | VFs | PGs | PPRS |
|---|---|---|---|
| 0 | 23 | 28 | 36.24 |
PPRS is classified as low-risk (≤4), medium-risk (4-6), and high-risk (≥6).
Antibiotic resistance genes
Comprehensive Antibiotic Resistance Database (CARD)
| Query ID | Begin | End | ARO name | ARO accession | CARD name | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
RGI v6.0.3 (Database: CARD Variants v4.0.2, Nov. 2023 release)
ResFinder
| Query ID | Begin | End | Resistance gene | Phenotype | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|
| No hit found | |||||||
ResFinder v4.6.0 (Database: resfinder_db, Aug. 2024 release)
AMRFinderPlus
| Query ID | Begin | End | Gene symbol | Sequence name | Method | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
AMRFinderPlus v4.0.3 (Database: Oct. 2024 release)
Virulence factors
Virulence Factor Database (VFDB)
| Query ID | qstart | qend | Gene name | e-value | VF name | VF category | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|---|
| DGFFODGD_1 | 1283486 | 1284745 | STER_RS07100 | 0.0 | Capsule | Immune modulation | 99.84 | 100.00 | WP_011681445 |
| DGFFODGD_1 | 1079876 | 1080469 | STR_RS05880 | 0.0 | Capsule | Immune modulation | 99.66 | 100.00 | WP_011226149 |
| DGFFODGD_1 | 43630 | 44469 | cbpD | 0.0 | Autolysin | Exoenzyme | 99.64 | 100.00 | WP_011226733 |
| DGFFODGD_1 | 1079876 | 1080469 | STER_RS06030 | 0.0 | Capsule | Immune modulation | 99.50 | 100.00 | WP_011226149 |
| DGFFODGD_1 | 1079876 | 1080469 | STU_RS15260 | 0.0 | Capsule | Immune modulation | 99.50 | 100.00 | WP_011226149 |
| DGFFODGD_1 | 1281526 | 1282494 | STER_RS07090 | 0.0 | Capsule | Immune modulation | 99.48 | 100.00 | WP_011681443 |
| DGFFODGD_1 | 849531 | 851189 | fbp54 | 0.0 | FBPs | Adherence | 99.46 | 100.00 | WP_011227179 |
| DGFFODGD_1 | 1282512 | 1283489 | STER_RS07095 | 0.0 | Capsule | Immune modulation | 99.39 | 100.00 | WP_011681444 |
| DGFFODGD_1 | 1115235 | 1115996 | srtA | 0.0 | Sortase A | Exoenzyme | 99.34 | 100.00 | - |
| DGFFODGD_1 | 966213 | 966812 | STR_RS05245 | 0.0 | Capsule | Immune modulation | 99.33 | 100.00 | WP_196767671 |
| DGFFODGD_1 | 968410 | 969141 | STR_RS05260 | 0.0 | Capsule | Immune modulation | 99.32 | 100.00 | WP_011227248 |
| DGFFODGD_1 | 1080469 | 1081338 | rfbA | 0.0 | Capsule | Immune modulation | 99.31 | 100.00 | WP_011681286 |
| DGFFODGD_1 | 968410 | 969141 | STU_RS14645 | 0.0 | Capsule | Immune modulation | 99.18 | 100.00 | WP_011226048 |
| DGFFODGD_1 | 945094 | 946509 | STER_RS05250 | 0.0 | Capsule | Immune modulation | 99.01 | 100.00 | WP_011681165 |
| DGFFODGD_1 | 968410 | 969141 | STER_RS05315 | 0.0 | Capsule | Immune modulation | 98.91 | 100.00 | WP_011681176 |
| DGFFODGD_1 | 1035034 | 1035823 | cshA | 0.0 | Cell surface hydrophobicity proteins | Adherence | 98.74 | 99.87 | - |
| DGFFODGD_1 | 969142 | 970596 | STR_RS05265 | 0.0 | Capsule | Immune modulation | 98.49 | 100.00 | WP_041827043 |
| DGFFODGD_1 | 965089 | 966048 | STR_RS05240 | 0.0 | Capsule | Immune modulation | 98.23 | 100.00 | WP_041827042 |
| DGFFODGD_1 | 969142 | 970596 | STU_RS14650 | 0.0 | Capsule | Immune modulation | 98.21 | 100.00 | WP_011226049 |
| DGFFODGD_1 | 1279693 | 1280463 | STER_RS07075 | 0.0 | Capsule | Immune modulation | 97.92 | 99.23 | WP_011681440 |
| DGFFODGD_1 | 1280809 | 1281524 | STER_RS07085 | 0.0 | Capsule | Immune modulation | 97.91 | 99.86 | WP_011681442 |
| DGFFODGD_1 | 967709 | 968401 | STR_RS05255 | 0.0 | Capsule | Immune modulation | 97.69 | 100.00 | WP_011227247 |
| DGFFODGD_1 | 967709 | 968401 | STU_RS14640 | 0.0 | Capsule | Immune modulation | 97.69 | 100.00 | WP_011226047 |
| DGFFODGD_1 | 966964 | 967699 | STER_RS05305 | 0.0 | Capsule | Immune modulation | 97.55 | 99.33 | WP_011681174 |
| DGFFODGD_1 | 969142 | 970596 | STER_RS05320 | 0.0 | Capsule | Immune modulation | 97.33 | 99.79 | WP_011681177 |
| DGFFODGD_1 | 966950 | 967699 | STR_RS05250 | 0.0 | Capsule | Immune modulation | 96.93 | 100.00 | WP_011227246 |
| DGFFODGD_1 | 966964 | 967699 | STU_RS14635 | 0.0 | Capsule | Immune modulation | 96.88 | 99.33 | WP_011226046 |
| DGFFODGD_1 | 1284864 | 1285715 | rfbD | 0.0 | Capsule | Immune modulation | 96.36 | 100.00 | WP_014621820 |
| DGFFODGD_1 | 967709 | 968401 | STER_RS05310 | 0.0 | Capsule | Immune modulation | 90.48 | 100.00 | WP_011681175 |
| DGFFODGD_1 | 591992 | 593295 | eno | 0.0 | Streptococcal enolase | Exoenzyme | 88.17 | 99.54 | WP_000022832 |
| DGFFODGD_1 | 1570517 | 1571527 | plr/gapA | 0.0 | Streptococcal plasmin receptor/GAPDH | Adherence | 86.82 | 99.51 | WP_002986042 |
| DGFFODGD_1 | 1078401 | 1079447 | rfbB | 0.0 | Capsule | Immune modulation | 80.71 | 100.00 | WP_009659423 |
| DGFFODGD_1 | 145200 | 146483 | tig/ropA | 0.0 | Trigger factor | Stress survival | 80.65 | 99.77 | WP_000107753 |
BLASTN v2.16.0 (Database: VFDB, Dec. 2024 release)
VirulenceFinder
| Query ID | Begin | End | Database | Virulence factor | Protein function | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
VirulenceFinder v2.0. 4 (Database: virulencefinder_db, Feb . 2024 release)
Pathogenic genes
PHI-base
| Query ID | qstart | qend | Gene name | e-value | Function | Identity | Coverage | Gene ID |
|---|---|---|---|---|---|---|---|---|
| DGFFODGD_1 | 1118683 | 1119666 | ldh(Sp_1220) | 0.0 | L-lactate dehydrogenase | 94.82 | 100.00 | AAK75326 |
| DGFFODGD_1 | 693063 | 694136 | MntE | 0.0 | manganese homeostasis | 94.41 | 99.72 | ABF32167 |
| DGFFODGD_1 | 508451 | 509419 | spr0084 | 0.0 | pathogenitcity related | 93.19 | 98.48 | AAK98888 |
| DGFFODGD_1 | 1450111 | 1452414 | pfl2(Sp_0459) | 0.0 | formate acetyltransferase | 93.10 | 99.22 | AAK74619 |
| DGFFODGD_1 | 1182293 | 1183774 | SPD_0310 | 0.0 | UPF0371 protein SPD_0310 | 92.11 | 100.00 | ABJ54480 |
| DGFFODGD_1 | 713584 | 715830 | metE | 0.0 | methionine biosynthesis enzymes | 91.86 | 100.00 | AAK74738 |
| DGFFODGD_1 | 27147 | 28118 | prsA2 | 0.0 | ribose-phosphate pyrophosphokinase | 90.12 | 100.00 | ABF36968 |
| DGFFODGD_1 | 1336354 | 1335203 | potA | 0.0 | ABC transporter ATP-binding protein-spermidine/putrescine transport | 89.06 | 99.74 | AAL00050 |
| DGFFODGD_1 | 1298963 | 1296975 | uvrB | 0.0 | excinuclease ABC, B subunit | 88.99 | 100.00 | AE014259_2 |
| DGFFODGD_1 | 1102488 | 1100758 | ptsI | 0.0 | phosphoenolpyruvate-protein phosphotransferase | 87.69 | 100.00 | AAK34199 |
| DGFFODGD_1 | 1756205 | 1754727 | IMPDH | 0.0 | inosine-5'-monophosphate dehydrogenase | 87.63 | 100.00 | ADE32434 |
| DGFFODGD_1 | 591992 | 593293 | Eno | 0.0 | enolase | 86.21 | 99.77 | ABP90468 |
| DGFFODGD_1 | 1741470 | 1739578 | gidA | 0.0 | tRNA uridine 5-carboxymethylaminomethyl modification enzyme | 85.89 | 98.90 | ABP91129 |
| DGFFODGD_1 | 63264 | 64370 | recA | 0.0 | DNA recombination and repair | 84.91 | 95.36 | AAL00560 |
| DGFFODGD_1 | 718755 | 717046 | PGM | 0.0 | phosphoglucomutase | 83.71 | 99.65 | ACH87041 |
| DGFFODGD_1 | 1612501 | 1613511 | pdh | 0.0 | pyruvate dehydrogenase | 83.38 | 99.70 | ABP91006 |
| DGFFODGD_1 | 877198 | 875837 | mnmE | 0.0 | central tRNA-modifying GTPase | 82.24 | 99.56 | ABP90420 |
| DGFFODGD_1 | 1662781 | 1660889 | PepO | 0.0 | endopeptidase | 80.03 | 100.00 | ABF32980 |
| DGFFODGD_1 | 577561 | 578451 | bglB | 1.27e-178 | putative phospho--glucosidase | 88.89 | 99.66 | AAK33487 |
| DGFFODGD_1 | 781707 | 780769 | SP_0676 | 7.83e-168 | transcription facot | 81.47 | 97.20 | AAK74821 |
| DGFFODGD_1 | 716022 | 716879 | metF | 8.25e-165 | methionine biosynthesis enzymes | 86.36 | 99.31 | AAK74739 |
| DGFFODGD_1 | 1007318 | 1006614 | covR | 3.34e-130 | responder protein | 84.68 | 100.00 | AAK71319 |
| DGFFODGD_1 | 1163330 | 1162659 | rr01 | 1.95e-125 | response regulator | 84.82 | 99.56 | CAB54566 |
| DGFFODGD_1 | 722708 | 723376 | CiaR | 1.64e-121 | two-component response regulator | 86.55 | 99.55 | AAK74935 |
| DGFFODGD_1 | 1007318 | 1006614 | walR | 2.40e-120 | DNA-binding response regulator | 80.85 | 100.00 | ANC99504 |
| DGFFODGD_1 | 722708 | 723379 | ciaR | 1.55e-119 | two component system response regulator | 84.38 | 99.12 | AIK75708 |
| DGFFODGD_1 | 294057 | 294743 | CovR | 9.60e-118 | serves to repress GAS virulence factor-encoding genes | 80.79 | 100.00 | ACE75886 |
| DGFFODGD_1 | 64554 | 64928 | SpxA2 | 1.10e-69 | transcriptional regulator | 91.20 | 94.70 | ERL21461 |
| DGFFODGD_1 | 146641 | 147141 | RopE (M5005_Spy_1611) | 4.69e-75 | probable DNA-directed RNA polymerase subunit delta | 81.44 | 87.43 | AAK34603 |
| DGFFODGD_1 | 1450111 | 1452408 | PFL (B9H01_RS01125) | 0.0 | formate C-acetyltransferase | 83.07 | 98.08 | MYN69560 |
| DGFFODGD_1 | 1648366 | 1647347 | ilvC (SPD_0406) | 0.0 | ketol-acid reductoisomerase (NADP(+)) | 96.47 | 100.00 | ABJ55451 |
BLASTX v2.16.0 (Database: PHI base v4.16, May. 2024 release)
Plasmid
PlasmidFinder
| Query ID | Begin | End | Plasmid | Query / Template | Identity | Accession no. |
|---|---|---|---|---|---|---|
| No hit found | ||||||
PlasmidFinder v 2.1.6 (Database: plasmidfinder_db v 2.2.0 , Nov. 2024 release)
PlasmidHunter
| Query ID | Prediction | Chromosome | Plasmid |
|---|---|---|---|
| DGFFODGD_1 | 0.0 | 1.0 | 0.0 |
PlasmidHunter v 1.4.5 (Database: May. 2024 release)
Prophage
Phigaro
| Query ID | Begin | End | Transposable | Taxonomy | pVOGs |
|---|---|---|---|---|---|
| No hit found | |||||
Phigaro v2.4.0 (Database: Jan. 2024 release)