GCA_003287475.1 - 4 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

gnlProkkaKEIKEFLO_6 (original name was: gnl|Prokka|KEIKEFLO_6)

Region	Type	From	To	Most similar known cluster		Similarity
Region 4.1	cyclic-lactone-autoinducer	3,204	24,683

gnlProkkaKEIKEFLO_13 (original name was: gnl|Prokka|KEIKEFLO_13)

Region	Type	From	To	Most similar known cluster		Similarity
Region 11.1	ranthipeptide	333,564	355,229

gnlProkkaKEIKEFLO_36 (original name was: gnl|Prokka|KEIKEFLO_36)

Region	Type	From	To	Most similar known cluster		Similarity
Region 34.1	lanthipeptide-class-ii	1	7,795

gnlProkkaKEIKEFLO_50 (original name was: gnl|Prokka|KEIKEFLO_50)

Region	Type	From	To	Most similar known cluster		Similarity
Region 48.1	lassopeptide	1	1,718

Region	Type	From	To	Similarity
Region 4.1	cyclic-lactone-autoinducer	3,204	24,683
Region 11.1	ranthipeptide	333,564	355,229
Region 34.1	lanthipeptide-class-ii	1	7,795
Region 48.1	lassopeptide	1	1,718

Compact view

gnlProkkaKEIKEFLO_6 - Region 1 - cyclic-lactone-autoinducer

Download region GenBank file

Download region SVG

Location: 3,204 - 24,683 nt. (total: 21,480 nt) Show pHMM detection rules used

Region on contig edge.

cyclic-lactone-autoinducer: (TIGR04223 or AgrB)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

Gene overview

KnownClusterBlast

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Similar known gene clusters from MIBiG 3.1

No matches found.

gnlProkkaKEIKEFLO_13 - Region 1 - ranthipeptide

Download region GenBank file

Download region SVG

Location: 333,564 - 355,229 nt. (total: 21,666 nt) Show pHMM detection rules used

ranthipeptide: (TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085 or SPASM)) and minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716 or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or (YcaO or TIGR03604))))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

Gene overview

KnownClusterBlast

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Similar known gene clusters from MIBiG 3.1

No matches found.

gnlProkkaKEIKEFLO_36 - Region 1 - lanthipeptide-class-ii

Download region GenBank file

Download region SVG

Location: 1 - 7,795 nt. (total: 7,795 nt) Show pHMM detection rules used

Region on contig edge.

lanthipeptide-class-ii: cds(LANC_like and DUF4135)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

Gene overview

KnownClusterBlast

Lanthipeptides

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Similar known gene clusters from MIBiG 3.1

No matches found.

Lanthipeptide predictions

Lanthipeptide(s) for ctg34_4

ctg34_3

Leader:

MNSNEKHEEIDCAELERLAAFGG

Core:

SDDSQINPCSDVATTTAIISAISSVVSAISNISAAMTKVPACKPKG

Core with dehydrations:

DhaDDDhaQINPCysDhaDVADhbDhbDhbAIIDhaAIDhaDhaVVDhaAIDhaNIDhaAAMDhbKVPACysKPKG

MIBiG 3.1 matches for ctg34_3

17.4% BGC0001229 (SBI_06990): Lanthipeptide: SBI-06990 A1 or SBI-06989 A2

15

TTAIISAISSVVSAISNISAAMTKVPACKP

44

T II +SS T C+P

7

TVKIIFRVSSHFGGNGGFGLFCTLSKECQP

36

17.4% BGC0002130 (QKI29070.1): Lanthipeptide: cacaoidin

8

PCSDVATTTAIISAISS

24

PC+ A+ +A ISA +S

4

PCTIYASVSASISATAS

20

antiSMASH-DB 4.0 matches for ctg34_3

100.0% NZ_QVFA01000004.1: Lanthipeptides: DW882_RS14120_lanthipeptide

1

SDDSQINPCSDVATTTAIISAISSVVSAISNISAAMTKVPACKPKG

46

SDDSQINPCSDVATTTAIISAISSVVSAISNISAAMTKVPACKPKG

1

SDDSQINPCSDVATTTAIISAISSVVSAISNISAAMTKVPACKPKG

46

93.5% NZ_JAQCXO010000012.1and 1 other:

NZ_QVFB01000013.1 Lanthipeptides: DW855_RS14250_lanthipeptide

Lanthipeptides: PGY55_RS14505_lanthipeptide

1

SDDSQINPCSDVATTTAIISAISSVVSAISNISAAMTKVPACKPKG

46

SDDSQINPCSDVATTTAII AISSVVSAIS ISAAM+KVPACKPKG

1

SDDSQINPCSDVATTTAIIGAISSVVSAISTISAAMSKVPACKPKG

46

30.4% NZ_BQXZ01000001.1and 1 other:

NZ_BQXZ01000001.1 Lanthipeptides: OCU69_RS05005_lanthipeptide

Lanthipeptides: OCU69_RS05005_lanthipeptide

16

TAIISAISSVVSAISNISAAMTKVPACKPK

45

T I+SAIS+ V++ + ISA T AC K

2

TPIVSAISATVASATAISALFTVTSACTTK

31

with 5 more sequence matches

26.1% NZ_CP086141.1and 1 other:

NZ_CP086141.1 Lanthipeptides: LL065_RS24780_lanthipeptide

Lanthipeptides: LL065_RS24780_lanthipeptide

15

TTAIISAISSVVSAISNISAAMTKVPAC

42

TT ++SAIS+ V++ + +SA T AC

1

TTPVVSAISATVASATAVSALFTVTSAC

28

23.9% NZ_QXPZ01000025.1: Lanthipeptides: D3H64_RS06235_lanthipeptide

15

TTAIISAISSVVSAISNISAAMTKVPAC

42

TT ++AIS++ ISN +TK +C

17

TTPELTAISALTVGISNF---VTKFKSC

41

21.7% NZ_CP086141.1and 1 other:

NZ_CP086141.1 Lanthipeptides: LL065_RS24780_lanthipeptide

Lanthipeptides: LL065_RS24780_lanthipeptide

19

ISAISSVVSAISNISAAMTKVPAC

42

+SAIS+ V++ + +SA T AC

1

VSAISATVASATAVSALFTVTSAC

24

17.4% NZ_CP036170.1and 1 other:

NZ_CP036170.1 Lanthipeptides: allorf_1760547_1760705_lanthipeptide

Lanthipeptides: allorf_1772186_1772344_lanthipeptide

13

ATTTAIISAISSVVSAISNISAAMTKVPACKPK

45

++ T +SA S ++ SN+ + +P C +

3

SSATPFLSASSECLATFSNLEMQHSPIPVCNFR

35

17.4% NZ_FOBB01000013.1: Lanthipeptides: BMZ54_RS31540_lanthipeptide

25

VVSAISNISAAMTKVPACKPKG

46

++ AIS A T P C +G

16

ILGAISYAECASTGQPTCNTQG

37

Legend:

Dha: Didehydroalanine
Dhb: Didehydrobutyrine

Lanthipeptides

Core peptide predictions

ctg34_3 - Class II

Cleavage pHMM score: -2.80

RODEO score: 0

Monoisotopic mass: 4314.3 Da

Molecular weight: 4316.9 Da

Number of bridges: 2

Alternative weights: (assuming N unmodified Ser/Thr residues); 4334.9 Da N = 1; 4352.9 Da N = 2; 4370.9 Da N = 3; 4389.0 Da N = 4; 4407.0 Da N = 5; 4425.0 Da N = 6; 4443.0 Da N = 7; 4461.0 Da N = 8; 4479.1 Da N = 9; 4497.1 Da N = 10; 4515.1 Da N = 11

gnlProkkaKEIKEFLO_50 - Region 1 - lassopeptide

Download region GenBank file

Download region SVG

Location: 1 - 1,718 nt. (total: 1,718 nt) Show pHMM detection rules used

Region on contig edge.

lassopeptide: (PF13471 and Asn_synthase or micJ25 or mcjC)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

Gene overview

KnownClusterBlast

Lasso peptides

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Similar known gene clusters from MIBiG 3.1

No matches found.

Lasso peptide predictions

Lassopeptides - No core peptides found.

Lasso peptides

Core peptide predictions

No core peptides found.