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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
IOLKFBCL_00002	2.35e-40	-	-	-	S	-	-	-	Helix-turn-helix domain
IOLKFBCL_00003	5.14e-112	-	-	-	S	ko:K18955	-	ko00000,ko03000	Transcription factor WhiB
IOLKFBCL_00004	3.57e-130	-	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	AAA domain
IOLKFBCL_00005	7.39e-54	-	-	-	-	-	-	-	-
IOLKFBCL_00006	0.0	-	-	-	S	-	-	-	ATPases associated with a variety of cellular activities
IOLKFBCL_00007	2.17e-122	-	-	-	K	-	-	-	FR47-like protein
IOLKFBCL_00008	2.32e-152	-	3.1.3.3	-	E	ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01009	haloacid dehalogenase-like hydrolase
IOLKFBCL_00009	0.0	-	-	-	D	-	-	-	Cell surface antigen C-terminus
IOLKFBCL_00011	7.45e-51	-	-	-	-	-	-	-	-
IOLKFBCL_00012	1.67e-187	-	-	-	-	-	-	-	-
IOLKFBCL_00013	1.99e-303	-	-	-	L	-	-	-	PFAM Integrase catalytic
IOLKFBCL_00014	1.98e-181	-	-	-	L	-	-	-	IstB-like ATP binding protein
IOLKFBCL_00015	9.69e-45	-	-	-	S	-	-	-	PrgI family protein
IOLKFBCL_00016	0.0	-	-	-	U	-	-	-	type IV secretory pathway VirB4
IOLKFBCL_00017	1.87e-254	-	-	-	M	-	-	-	CHAP domain
IOLKFBCL_00018	1.74e-246	-	-	-	-	-	-	-	-
IOLKFBCL_00019	3.66e-58	-	-	-	-	-	-	-	-
IOLKFBCL_00020	8.15e-183	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
IOLKFBCL_00021	6.17e-261	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
IOLKFBCL_00023	4.11e-34	-	-	-	K	ko:K03088	-	ko00000,ko03021	Psort location Cytoplasmic, score
IOLKFBCL_00024	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
IOLKFBCL_00025	6.69e-142	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
IOLKFBCL_00026	4.66e-147	-	-	-	T	-	-	-	Histidine kinase
IOLKFBCL_00027	1.34e-137	-	-	-	K	-	-	-	COG COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IOLKFBCL_00028	1.69e-30	-	-	-	K	-	-	-	trisaccharide binding
IOLKFBCL_00029	6.49e-57	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
IOLKFBCL_00030	2.62e-152	-	-	-	M	-	-	-	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IOLKFBCL_00031	1.01e-164	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
IOLKFBCL_00032	2.94e-224	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
IOLKFBCL_00033	7.02e-114	-	-	-	-	-	-	-	-
IOLKFBCL_00034	3.57e-267	-	-	-	L	ko:K07485	-	ko00000	Transposase
IOLKFBCL_00036	1.87e-164	-	-	-	S	ko:K11939	-	ko00000,ko02000	EamA-like transporter family
IOLKFBCL_00037	1.37e-228	-	-	-	L	-	-	-	Transposase
IOLKFBCL_00038	1.19e-14	-	-	-	-	-	-	-	-
IOLKFBCL_00040	7.79e-16	intA	-	-	L	-	-	-	Phage integrase family
IOLKFBCL_00042	1.51e-26	-	-	-	-	-	-	-	-
IOLKFBCL_00043	3.87e-95	intA	-	-	L	-	-	-	Phage integrase family
IOLKFBCL_00044	1.95e-195	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
IOLKFBCL_00047	2.32e-212	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 7.50
IOLKFBCL_00048	8.96e-149	-	-	-	S	-	-	-	AAA ATPase domain
IOLKFBCL_00049	0.0	-	-	-	U	-	-	-	Drug resistance MFS transporter, drug H antiporter-2 family
IOLKFBCL_00050	1.29e-266	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
IOLKFBCL_00051	2.13e-173	-	-	-	L	-	-	-	Protein of unknown function (DUF1524)
IOLKFBCL_00052	5.08e-153	-	-	-	S	-	-	-	Oxidoreductase, aldo keto reductase family protein
IOLKFBCL_00053	0.0	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IOLKFBCL_00054	4.02e-140	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IOLKFBCL_00055	2.59e-213	tcsS2	-	-	T	-	-	-	Histidine kinase
IOLKFBCL_00056	3.65e-119	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
IOLKFBCL_00057	1.27e-112	tnp7109-2	-	-	L	ko:K07493	-	ko00000	Transposase, Mutator family
IOLKFBCL_00058	4.88e-62	tnp7109-2	-	-	L	ko:K07493	-	ko00000	Transposase, Mutator family
IOLKFBCL_00060	4.39e-19	-	-	-	L	-	-	-	Transposase
IOLKFBCL_00061	4.69e-218	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
IOLKFBCL_00063	1.71e-31	-	-	-	L	-	-	-	Transposase
IOLKFBCL_00065	2.53e-129	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
IOLKFBCL_00066	1.43e-301	-	-	-	-	-	-	-	-
IOLKFBCL_00067	1.95e-26	-	-	-	S	-	-	-	Bacteriocin (Lactococcin_972)
IOLKFBCL_00068	2.34e-34	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
IOLKFBCL_00069	5.88e-126	-	-	-	T	-	-	-	Histidine kinase
IOLKFBCL_00070	3.57e-311	-	-	-	U	ko:K02100	-	ko00000,ko02000	Sugar (and other) transporter
IOLKFBCL_00071	1.21e-142	-	-	-	V	ko:K06147,ko:K06148,ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter transmembrane region
IOLKFBCL_00072	4.6e-135	-	-	-	V	ko:K06147,ko:K06148,ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter transmembrane region
IOLKFBCL_00073	3.39e-31	araE	-	-	EGP	ko:K02100	-	ko00000,ko02000	Major facilitator Superfamily
IOLKFBCL_00074	0.0	fadD	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme
IOLKFBCL_00075	1.33e-171	-	3.2.1.51	GH29	G	ko:K01206	ko00511,map00511	ko00000,ko00001,ko01000,ko04147	Alpha-L-fucosidase
IOLKFBCL_00078	4.15e-262	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
IOLKFBCL_00079	1.65e-266	-	-	-	T	-	-	-	Histidine kinase
IOLKFBCL_00080	1.53e-138	-	-	-	K	-	-	-	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IOLKFBCL_00081	8.13e-93	-	-	-	V	ko:K01990,ko:K01992	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
IOLKFBCL_00082	3.12e-175	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
IOLKFBCL_00083	2.31e-166	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
IOLKFBCL_00084	1.22e-150	-	-	-	-	-	-	-	-
IOLKFBCL_00086	1.92e-91	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
IOLKFBCL_00087	2.15e-48	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
IOLKFBCL_00088	4.24e-97	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-stranded DNA-binding protein
IOLKFBCL_00089	2.77e-64	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
IOLKFBCL_00090	6.23e-243	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IOLKFBCL_00091	6.88e-171	-	-	-	S	ko:K06997	-	ko00000	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
IOLKFBCL_00092	0.0	-	-	-	S	ko:K03688	-	ko00000	ABC1 family
IOLKFBCL_00093	2.4e-51	-	-	-	S	-	-	-	granule-associated protein
IOLKFBCL_00094	1.98e-184	cobQ2	-	-	S	ko:K07009	-	ko00000	CobB/CobQ-like glutamine amidotransferase domain
IOLKFBCL_00095	0.0	murE	-	-	M	-	-	-	Domain of unknown function (DUF1727)
IOLKFBCL_00096	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
IOLKFBCL_00097	0.0	dinF	-	-	V	-	-	-	MatE
IOLKFBCL_00098	0.0	glnD	2.7.7.59	-	O	ko:K00990	ko02020,map02020	ko00000,ko00001,ko01000	Nucleotidyltransferase domain
IOLKFBCL_00099	7.34e-72	glnB	-	-	K	ko:K04751	ko02020,map02020	ko00000,ko00001	Nitrogen regulatory protein P-II
IOLKFBCL_00100	1.59e-304	amt	-	-	U	ko:K03320	-	ko00000,ko02000	Ammonium Transporter Family
IOLKFBCL_00101	1.78e-238	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
IOLKFBCL_00102	3.96e-23	-	-	-	-	-	-	-	-
IOLKFBCL_00103	8.23e-62	-	-	-	S	-	-	-	Protein of unknown function (DUF2089)
IOLKFBCL_00104	5.43e-157	icaR	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
IOLKFBCL_00105	9.5e-239	-	2.7.8.12	-	M	ko:K09809	-	ko00000,ko01000	Glycosyltransferase like family 2
IOLKFBCL_00106	0.0	-	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Peptidase family C69
IOLKFBCL_00108	1.64e-12	-	-	-	-	-	-	-	-
IOLKFBCL_00110	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
IOLKFBCL_00111	1.24e-235	opcA	-	-	G	-	-	-	Glucose-6-phosphate dehydrogenase subunit
IOLKFBCL_00112	2.51e-177	pgl	3.1.1.31	-	G	ko:K01057	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase
IOLKFBCL_00113	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
IOLKFBCL_00114	1.76e-295	-	-	-	S	-	-	-	Putative ABC-transporter type IV
IOLKFBCL_00115	0.0	-	-	-	S	ko:K01421	-	ko00000	YhgE Pip domain protein
IOLKFBCL_00116	0.0	-	-	-	S	ko:K01421	-	ko00000	YhgE Pip domain protein
IOLKFBCL_00117	2.34e-135	-	-	-	K	-	-	-	Psort location Cytoplasmic, score 8.87
IOLKFBCL_00118	9.42e-111	-	-	-	S	-	-	-	FMN_bind
IOLKFBCL_00119	4.85e-188	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IOLKFBCL_00120	3.66e-275	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
IOLKFBCL_00121	1.66e-287	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
IOLKFBCL_00122	1.28e-294	-	-	-	S	-	-	-	Predicted membrane protein (DUF2318)
IOLKFBCL_00123	1.43e-154	-	-	-	P	ko:K07230	-	ko00000,ko02000	Fe2+ transport protein
IOLKFBCL_00124	0.0	-	-	-	P	ko:K07243	-	ko00000,ko02000	Iron permease FTR1 family
IOLKFBCL_00125	0.0	-	-	-	-	-	-	-	-
IOLKFBCL_00127	2.21e-218	-	-	-	-	-	-	-	-
IOLKFBCL_00129	1e-82	-	-	-	-	-	-	-	-
IOLKFBCL_00130	1.31e-288	-	2.1.1.113	-	L	ko:K00590	-	ko00000,ko01000,ko02048	Belongs to the N(4) N(6)-methyltransferase family
IOLKFBCL_00131	4.49e-238	-	-	-	L	ko:K07485	-	ko00000	Transposase
IOLKFBCL_00132	5.06e-178	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
IOLKFBCL_00133	8.81e-103	-	-	-	-	-	-	-	-
IOLKFBCL_00136	7.61e-228	-	-	-	S	ko:K07133	-	ko00000	Domain of unknown function (DUF4143)
IOLKFBCL_00137	8e-33	-	-	-	S	ko:K07133	-	ko00000	AAA domain
IOLKFBCL_00139	0.0	gltX	6.1.1.17	-	J	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IOLKFBCL_00140	3.96e-197	-	-	-	S	-	-	-	Protein of unknown function (DUF805)
IOLKFBCL_00141	8.26e-218	-	5.1.3.15	-	G	ko:K01792	ko00010,ko01100,ko01110,ko01120,ko01130,map00010,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Aldose 1-epimerase
IOLKFBCL_00142	9.75e-202	-	-	-	-	-	-	-	-
IOLKFBCL_00143	6.16e-159	-	-	-	G	-	-	-	Phosphoglycerate mutase family
IOLKFBCL_00144	0.0	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
IOLKFBCL_00145	1.83e-124	-	-	-	S	-	-	-	GtrA-like protein
IOLKFBCL_00146	5.49e-82	-	-	-	S	-	-	-	Macrophage migration inhibitory factor (MIF)
IOLKFBCL_00147	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Formate-tetrahydrofolate ligase
IOLKFBCL_00148	0.0	pepD	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Peptidase family C69
IOLKFBCL_00149	1.46e-135	-	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
IOLKFBCL_00150	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IOLKFBCL_00151	1.47e-50	hpr	-	-	G	ko:K11189	-	ko00000,ko02000	PTS HPr component phosphorylation site
IOLKFBCL_00152	1.6e-131	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
IOLKFBCL_00153	2.31e-259	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
IOLKFBCL_00154	3.65e-158	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IOLKFBCL_00155	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IOLKFBCL_00156	1.81e-212	-	-	-	I	-	-	-	PAP2 superfamily
IOLKFBCL_00157	0.0	pbp5	-	-	M	-	-	-	Transglycosylase
IOLKFBCL_00158	0.0	leuA	2.3.3.13	-	E	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IOLKFBCL_00159	0.0	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
IOLKFBCL_00160	1.25e-147	-	-	-	-	-	-	-	-
IOLKFBCL_00161	2.54e-267	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IOLKFBCL_00162	1.17e-125	ask	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	ACT domain
IOLKFBCL_00163	3.35e-169	ask	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Amino acid kinase family
IOLKFBCL_00164	1.06e-64	-	-	-	S	ko:K07133	-	ko00000	Psort location Cytoplasmic, score
IOLKFBCL_00165	8.03e-257	-	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
IOLKFBCL_00166	1.93e-139	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IOLKFBCL_00167	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III subunit gamma tau
IOLKFBCL_00168	9.91e-137	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
IOLKFBCL_00169	4.26e-272	-	2.7.1.107	-	I	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Diacylglycerol kinase catalytic domain protein
IOLKFBCL_00170	4.43e-70	-	-	-	S	-	-	-	TIGRFAM helicase secretion neighborhood TadE-like protein
IOLKFBCL_00171	3.54e-53	-	-	-	S	-	-	-	Protein of unknown function (DUF4244)
IOLKFBCL_00172	1.63e-131	-	-	-	NU	-	-	-	Type II secretion system (T2SS), protein F
IOLKFBCL_00173	1.72e-135	-	-	-	U	ko:K12510	-	ko00000,ko02044	Type ii secretion system
IOLKFBCL_00174	1.12e-245	cpaF	-	-	U	ko:K02283	-	ko00000,ko02035,ko02044	Type II IV secretion system protein
IOLKFBCL_00175	7.3e-120	-	-	-	D	-	-	-	bacterial-type flagellum organization
IOLKFBCL_00176	2.59e-171	dedA1	-	-	S	ko:K03975	-	ko00000	SNARE associated Golgi protein
IOLKFBCL_00177	5.91e-159	-	-	-	S	-	-	-	HAD hydrolase, family IA, variant 3
IOLKFBCL_00178	9.22e-181	-	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Oxidoreductase, short chain dehydrogenase reductase family protein
IOLKFBCL_00179	3.35e-291	-	-	-	C	-	-	-	Acyl-CoA reductase (LuxC)
IOLKFBCL_00180	6.13e-263	-	-	-	H	-	-	-	long-chain-fatty-acid--luciferin-component ligase, acyl-protein synthase
IOLKFBCL_00181	2.88e-270	-	-	-	F	-	-	-	Psort location CytoplasmicMembrane, score 10.00
IOLKFBCL_00182	5.09e-128	hspR	-	-	K	ko:K13640	-	ko00000,ko03000	transcriptional regulator, MerR family
IOLKFBCL_00183	3.79e-231	dnaJ	-	-	O	ko:K03686,ko:K05516	-	ko00000,ko03029,ko03036,ko03110	DnaJ molecular chaperone homology domain
IOLKFBCL_00184	2.8e-95	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
IOLKFBCL_00185	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
IOLKFBCL_00186	0.0	strK	3.1.3.1, 3.1.3.39	-	P	ko:K01077,ko:K04342	ko00521,ko00730,ko00790,ko01100,ko01130,ko02020,map00521,map00730,map00790,map01100,map01130,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	Alkaline phosphatase homologues
IOLKFBCL_00187	0.0	malQ	2.4.1.25	GH77	G	ko:K00705	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	4-alpha-glucanotransferase
IOLKFBCL_00188	4.02e-238	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
IOLKFBCL_00189	0.0	-	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha-amylase domain
IOLKFBCL_00190	5.06e-260	ilvC	1.1.1.86	-	H	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
IOLKFBCL_00191	1.09e-74	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
IOLKFBCL_00192	4.04e-91	bioM	-	-	P	ko:K16784	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
IOLKFBCL_00193	4.44e-65	bioN	-	-	P	ko:K16783	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
IOLKFBCL_00194	8.38e-259	ilvC	1.1.1.86	-	H	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
IOLKFBCL_00195	0.0	-	-	-	EGP	-	-	-	Sugar (and other) transporter
IOLKFBCL_00197	0.0	scrT	-	-	G	-	-	-	Transporter major facilitator family protein
IOLKFBCL_00198	0.0	gtfA	2.4.1.7	GH13	G	ko:K00690	ko00500,map00500	ko00000,ko00001,ko01000	Domain of unknown function (DUF1964)
IOLKFBCL_00199	3.83e-256	-	-	-	K	ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
IOLKFBCL_00200	5.18e-81	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IOLKFBCL_00201	4.08e-199	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IOLKFBCL_00202	0.0	-	-	-	P	ko:K03281	-	ko00000	Voltage gated chloride channel
IOLKFBCL_00203	9.71e-317	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IOLKFBCL_00204	7.23e-263	fbaA	4.1.2.13	-	G	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-bisphosphate aldolase class-II
IOLKFBCL_00205	2.85e-152	mug	3.2.2.28	-	L	ko:K03649	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Uracil DNA glycosylase superfamily
IOLKFBCL_00206	7.78e-262	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
IOLKFBCL_00208	1.55e-125	-	3.2.1.4	GH5,GH9	S	ko:K01179,ko:K21449	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000,ko02000	acid phosphatase activity
IOLKFBCL_00209	5.53e-205	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
IOLKFBCL_00210	0.0	fprA	1.18.1.2, 1.19.1.1	-	C	ko:K00528	-	ko00000,ko01000	Pyridine nucleotide-disulphide oxidoreductase
IOLKFBCL_00211	4.01e-260	-	-	-	M	-	-	-	LPXTG cell wall anchor motif
IOLKFBCL_00212	6.26e-125	-	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
IOLKFBCL_00213	1.81e-116	ureD	-	-	O	ko:K03190	-	ko00000	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
IOLKFBCL_00214	3.67e-127	ureG	-	-	KO	ko:K03189	-	ko00000	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
IOLKFBCL_00215	1.13e-101	ureF	-	-	J	ko:K03188	-	ko00000	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
IOLKFBCL_00216	9.64e-113	ureE	-	-	O	ko:K03187	-	ko00000	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
IOLKFBCL_00217	0.0	ureC	3.5.1.5	-	E	ko:K01427,ko:K01428	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120	ko00000,ko00001,ko01000	Urease alpha-subunit, N-terminal domain
IOLKFBCL_00218	6.14e-123	ureA	3.5.1.5	-	E	ko:K01430,ko:K14048	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120	ko00000,ko00001,ko01000	Urease, gamma subunit
IOLKFBCL_00219	2.66e-138	hoxN	-	-	U	ko:K07241	-	ko00000,ko02000	Belongs to the NiCoT transporter (TC 2.A.52) family
IOLKFBCL_00220	8.34e-128	urtE	-	-	E	ko:K11963	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
IOLKFBCL_00221	4.04e-147	urtD	-	-	S	ko:K11962	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid ATP-binding cassette transporter
IOLKFBCL_00222	2.7e-203	urtC	-	-	U	ko:K01998,ko:K11961	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid transport system / permease component
IOLKFBCL_00223	7.88e-165	urtB	-	-	U	ko:K11960	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid transport system / permease component
IOLKFBCL_00224	2.77e-247	urtA	-	-	E	ko:K11959	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Receptor family ligand binding region
IOLKFBCL_00225	0.0	-	3.6.3.4, 3.6.3.54	-	P	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	E1-E2 ATPase
IOLKFBCL_00226	0.0	degP	-	-	O	ko:K08372	ko02020,map02020	ko00000,ko00001,ko01000,ko01002	Domain present in PSD-95, Dlg, and ZO-1/2.
IOLKFBCL_00227	0.0	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
IOLKFBCL_00230	4.84e-72	-	-	-	S	-	-	-	PfpI family
IOLKFBCL_00231	4.14e-93	-	-	-	O	-	-	-	Hsp20/alpha crystallin family
IOLKFBCL_00232	8.94e-163	-	-	-	S	ko:K11068	-	ko00000,ko02042	Haemolysin-III related
IOLKFBCL_00233	5.86e-68	-	-	-	S	-	-	-	Putative heavy-metal-binding
IOLKFBCL_00234	1.64e-98	mutT	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
IOLKFBCL_00235	0.0	-	-	-	KL	-	-	-	Domain of unknown function (DUF3427)
IOLKFBCL_00236	1.53e-208	-	-	-	M	-	-	-	Glycosyltransferase like family 2
IOLKFBCL_00237	5.55e-143	-	-	-	S	ko:K07005	-	ko00000	Pyridoxamine 5'-phosphate oxidase
IOLKFBCL_00238	6.74e-245	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IOLKFBCL_00239	0.0	lysX	-	-	S	-	-	-	Uncharacterised conserved protein (DUF2156)
IOLKFBCL_00240	1.47e-285	-	-	-	S	-	-	-	Putative esterase
IOLKFBCL_00241	4.22e-188	-	-	-	EG	-	-	-	EamA-like transporter family
IOLKFBCL_00242	3.04e-262	pldB	3.1.1.5	-	I	ko:K01048	ko00564,map00564	ko00000,ko00001,ko01000	Serine aminopeptidase, S33
IOLKFBCL_00243	0.0	pepX	3.4.14.5	-	E	ko:K01278	ko04974,map04974	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	Dipeptidyl peptidase IV (DPP IV) N-terminal region
IOLKFBCL_00244	6.12e-166	fhaA	-	-	T	-	-	-	Protein of unknown function (DUF2662)
IOLKFBCL_00245	1.73e-82	fhaB	-	-	T	-	-	-	Inner membrane component of T3SS, cytoplasmic domain
IOLKFBCL_00246	0.0	pstP	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	Sigma factor PP2C-like phosphatases
IOLKFBCL_00247	0.0	rodA	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
IOLKFBCL_00248	0.0	pbpA	-	-	M	ko:K05364	ko00550,map00550	ko00000,ko00001,ko01011	penicillin-binding protein
IOLKFBCL_00249	3.11e-221	pknA	2.7.11.1	-	T	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	Protein tyrosine kinase
IOLKFBCL_00250	0.0	pknB	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	Protein tyrosine kinase
IOLKFBCL_00251	7.5e-153	trpG	2.6.1.85, 4.1.3.27	-	EH	ko:K01658,ko:K01664	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	para-aminobenzoate synthase glutamine amidotransferase component II
IOLKFBCL_00252	1.5e-297	srtB	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
IOLKFBCL_00253	1.64e-156	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF881)
IOLKFBCL_00254	3.01e-106	crgA	-	-	D	-	-	-	Involved in cell division
IOLKFBCL_00255	9.63e-162	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Rhomboid family
IOLKFBCL_00256	2.06e-46	-	-	-	-	-	-	-	-
IOLKFBCL_00257	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
IOLKFBCL_00258	4.68e-99	-	-	-	I	-	-	-	Sterol carrier protein
IOLKFBCL_00259	5.79e-306	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
IOLKFBCL_00260	2.63e-265	-	-	-	T	-	-	-	Histidine kinase
IOLKFBCL_00261	5.37e-146	-	-	-	K	-	-	-	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IOLKFBCL_00262	4.19e-58	-	-	-	S	-	-	-	Protein of unknown function (DUF3073)
IOLKFBCL_00263	4.29e-254	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
IOLKFBCL_00264	9.06e-136	-	-	-	S	-	-	-	Nucleotidyl transferase AbiEii toxin, Type IV TA system
IOLKFBCL_00265	8.11e-72	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
IOLKFBCL_00266	0.0	-	-	-	E	ko:K11928	-	ko00000,ko02000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IOLKFBCL_00267	1.65e-120	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
IOLKFBCL_00268	1.48e-14	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
IOLKFBCL_00269	0.0	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
IOLKFBCL_00270	0.0	ppc	4.1.1.31	-	H	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
IOLKFBCL_00272	0.0	-	-	-	M	-	-	-	Domain of unknown function (DUF1906)
IOLKFBCL_00275	1.92e-141	-	-	-	-	-	-	-	-
IOLKFBCL_00277	4.51e-198	-	-	-	L	ko:K03546	-	ko00000,ko03400	ATPase involved in DNA repair
IOLKFBCL_00278	5.6e-45	ppc	4.1.1.31	-	H	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
IOLKFBCL_00280	2.38e-83	-	-	-	M	-	-	-	Domain of unknown function (DUF1906)
IOLKFBCL_00281	2.49e-186	-	-	-	P	ko:K02031,ko:K02032,ko:K13892	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
IOLKFBCL_00282	1.73e-121	-	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	PFAM binding-protein-dependent transport systems inner membrane component
IOLKFBCL_00283	1.64e-157	appB	-	-	P	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	PFAM binding-protein-dependent transport systems inner membrane component
IOLKFBCL_00284	2.76e-239	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	family 5
IOLKFBCL_00285	1.34e-12	-	-	-	-	-	-	-	-
IOLKFBCL_00286	0.0	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative ATP-dependent DNA helicase recG C-terminal
IOLKFBCL_00287	1.62e-294	-	-	-	S	ko:K07133	-	ko00000	AAA domain
IOLKFBCL_00288	3.8e-226	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOLKFBCL_00289	7.54e-211	-	-	-	P	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOLKFBCL_00290	0.0	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
IOLKFBCL_00292	0.0	-	-	-	P	-	-	-	Domain of unknown function (DUF4976)
IOLKFBCL_00293	2.75e-245	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
IOLKFBCL_00294	0.0	-	-	-	C	ko:K06871	-	ko00000	Iron-sulfur cluster-binding domain
IOLKFBCL_00295	1.64e-171	-	-	-	S	ko:K07090	-	ko00000	Sulfite exporter TauE/SafE
IOLKFBCL_00297	8.9e-123	-	-	-	C	ko:K06871	-	ko00000	radical SAM
IOLKFBCL_00298	8.86e-107	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IOLKFBCL_00299	8.83e-106	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
IOLKFBCL_00300	3.37e-229	-	-	-	L	-	-	-	Transposase
IOLKFBCL_00301	2.54e-183	-	-	-	S	ko:K07133	-	ko00000	Domain of unknown function (DUF4143)
IOLKFBCL_00302	2.65e-306	-	-	-	EGP	ko:K08177	-	ko00000,ko02000	Major Facilitator Superfamily
IOLKFBCL_00303	0.0	-	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Thioredoxin domain
IOLKFBCL_00304	9.71e-138	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	C-terminal domain of 1-Cys peroxiredoxin
IOLKFBCL_00305	1.28e-155	cah	4.2.1.1	-	P	ko:K01673	ko00910,map00910	ko00000,ko00001,ko01000	Reversible hydration of carbon dioxide
IOLKFBCL_00306	5.94e-87	-	-	-	V	ko:K01990,ko:K21397	-	ko00000,ko00002,ko02000	Forkhead associated domain
IOLKFBCL_00307	5.24e-258	-	-	-	S	-	-	-	AAA ATPase domain
IOLKFBCL_00308	3.36e-305	-	-	-	P	ko:K03699	-	ko00000,ko02042	Transporter associated domain
IOLKFBCL_00309	5.42e-110	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
IOLKFBCL_00310	4.39e-191	gnd	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	6-phosphogluconate dehydrogenase, C-terminal domain
IOLKFBCL_00311	8.79e-112	gntK	2.7.1.12, 2.7.1.71	-	F	ko:K00851,ko:K00891	ko00030,ko00400,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00400,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Shikimate kinase
IOLKFBCL_00312	5.1e-294	gnuT	-	-	EG	ko:K03299	-	ko00000,ko02000	GntP family permease
IOLKFBCL_00313	5.44e-119	-	-	-	K	-	-	-	FCD
IOLKFBCL_00314	1.24e-187	-	-	-	S	ko:K07043	-	ko00000	Protein of unknown function DUF45
IOLKFBCL_00315	6.13e-257	-	-	-	S	ko:K07133	-	ko00000	Domain of unknown function (DUF4143)
IOLKFBCL_00316	5.22e-34	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
IOLKFBCL_00317	4.19e-24	-	-	-	K	-	-	-	Transcriptional regulator, rpir family
IOLKFBCL_00318	6.71e-144	-	-	-	P	ko:K02044	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, phosphonate, periplasmic substrate-binding protein
IOLKFBCL_00319	1.7e-104	phnC	3.6.3.28	-	P	ko:K02041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
IOLKFBCL_00320	5.11e-101	-	-	-	U	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOLKFBCL_00321	8.22e-105	ptxC	-	-	U	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOLKFBCL_00322	2.19e-74	-	-	-	F	-	-	-	Calcineurin-like phosphoesterase
IOLKFBCL_00326	1.49e-48	-	-	-	-	-	-	-	-
IOLKFBCL_00327	1.35e-55	-	-	-	L	-	-	-	PFAM Integrase catalytic
IOLKFBCL_00328	3.58e-38	-	-	-	L	-	-	-	RelB antitoxin
IOLKFBCL_00330	1.24e-86	-	-	-	K	-	-	-	Transcriptional regulator, rpir family
IOLKFBCL_00331	3.12e-166	-	-	-	P	ko:K02012	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
IOLKFBCL_00332	1.94e-245	-	-	-	P	ko:K02011	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport systems inner membrane component
IOLKFBCL_00333	2.66e-126	-	3.6.3.30	-	E	ko:K02010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
IOLKFBCL_00334	2.28e-143	cpdA	2.1.2.2, 3.1.3.48, 3.1.4.17, 3.1.4.53	-	T	ko:K01104,ko:K01120,ko:K03651,ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,ko02025,map00230,map00670,map01100,map01110,map01130,map02025	ko00000,ko00001,ko00002,ko01000	protein tyrosine phosphatase activity
IOLKFBCL_00335	9.28e-317	gdhA	1.4.1.4	-	E	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
IOLKFBCL_00336	0.0	-	-	-	S	ko:K06921	-	ko00000	ATPase domain predominantly from Archaea
IOLKFBCL_00337	1.08e-105	-	-	-	S	-	-	-	Transmembrane domain of unknown function (DUF3566)
IOLKFBCL_00338	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IOLKFBCL_00339	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IOLKFBCL_00340	2.31e-105	-	-	-	S	-	-	-	Protein of unknown function (DUF721)
IOLKFBCL_00341	1.93e-284	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IOLKFBCL_00342	6.2e-264	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
IOLKFBCL_00343	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IOLKFBCL_00344	3.25e-20	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
IOLKFBCL_00345	5.81e-45	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
IOLKFBCL_00346	4.24e-224	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Membrane protein insertase, YidC Oxa1 family
IOLKFBCL_00347	2.13e-118	jag	-	-	S	ko:K06346	-	ko00000	Putative single-stranded nucleic acids-binding domain
IOLKFBCL_00348	2.41e-157	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
IOLKFBCL_00349	1.49e-227	parA	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	CobQ CobB MinD ParA nucleotide binding domain protein
IOLKFBCL_00350	3.36e-292	parB	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
IOLKFBCL_00351	3.71e-236	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
IOLKFBCL_00352	0.0	-	-	-	KLT	ko:K03980	-	ko00000,ko01011,ko02000	MviN-like protein
IOLKFBCL_00353	9.77e-269	mviN	-	-	KLT	ko:K03980	-	ko00000,ko01011,ko02000	MviN-like protein
IOLKFBCL_00354	0.0	-	-	-	-	-	-	-	-
IOLKFBCL_00355	1.66e-262	mutT4	-	-	L	-	-	-	Belongs to the Nudix hydrolase family
IOLKFBCL_00356	0.0	pcnA	2.7.7.19, 2.7.7.72	-	J	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	Probable RNA and SrmB- binding site of polymerase A
IOLKFBCL_00357	3.83e-139	-	-	-	S	-	-	-	LytR cell envelope-related transcriptional attenuator
IOLKFBCL_00358	1.8e-220	ispE	2.7.1.148	-	F	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
IOLKFBCL_00359	2.74e-213	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
IOLKFBCL_00360	2.61e-280	rpfB	-	-	S	ko:K21688	-	ko00000	G5
IOLKFBCL_00362	6.2e-172	-	-	-	O	-	-	-	Thioredoxin
IOLKFBCL_00363	0.0	-	-	-	KLT	-	-	-	Protein tyrosine kinase
IOLKFBCL_00364	1.62e-57	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
IOLKFBCL_00365	1.03e-106	nrdI	-	-	F	ko:K03647	-	ko00000	Probably involved in ribonucleotide reductase function
IOLKFBCL_00366	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IOLKFBCL_00368	7.28e-243	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IOLKFBCL_00369	3.15e-277	-	-	-	M	-	-	-	Glycosyltransferase like family 2
IOLKFBCL_00370	1.47e-267	ugpC	-	-	E	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
IOLKFBCL_00371	0.0	-	-	-	KLT	-	-	-	Domain of unknown function (DUF4032)
IOLKFBCL_00372	2.64e-220	rlmB	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IOLKFBCL_00373	1.27e-257	-	-	-	EGP	-	-	-	Transmembrane secretion effector
IOLKFBCL_00374	0.0	-	-	-	S	ko:K07133	-	ko00000	Domain of unknown function (DUF4143)
IOLKFBCL_00375	4.7e-60	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
IOLKFBCL_00376	9.63e-73	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Extracellular solute-binding protein
IOLKFBCL_00377	1.39e-95	-	-	-	G	ko:K02025	-	ko00000,ko00002,ko02000	PFAM binding-protein-dependent transport systems inner membrane component
IOLKFBCL_00378	9.88e-92	-	-	-	G	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport systems inner membrane component
IOLKFBCL_00379	4.62e-14	-	-	-	L	-	-	-	Transposase DDE domain
IOLKFBCL_00380	7.59e-61	-	-	-	L	-	-	-	Transposase
IOLKFBCL_00381	4.27e-121	-	-	-	-	-	-	-	-
IOLKFBCL_00382	3.02e-281	-	-	-	G	-	-	-	Domain of unknown function (DUF4091)
IOLKFBCL_00383	0.0	nagE	2.7.1.193	-	G	ko:K02802,ko:K02803,ko:K02804	ko00520,ko02060,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
IOLKFBCL_00384	2.15e-110	-	2.7.1.208	-	G	ko:K02777,ko:K20107,ko:K20108	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
IOLKFBCL_00385	4.12e-21	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
IOLKFBCL_00386	0.0	pacL2	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	Cation transporter/ATPase, N-terminus
IOLKFBCL_00387	8.83e-210	-	-	-	G	-	-	-	Glycosyl hydrolase, family 20, catalytic domain
IOLKFBCL_00388	2.58e-220	-	-	-	U	ko:K06956	-	ko00000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
IOLKFBCL_00389	4.31e-184	-	-	-	-	-	-	-	-
IOLKFBCL_00390	4.97e-143	dcd	3.5.4.13	-	F	ko:K01494	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dCTP deaminase family
IOLKFBCL_00391	1.31e-93	scrK	-	-	G	-	-	-	pfkB family carbohydrate kinase
IOLKFBCL_00392	6.76e-114	-	-	-	K	ko:K02444	-	ko00000,ko03000	DeoR C terminal sensor domain
IOLKFBCL_00393	3.76e-233	-	3.2.1.86	GT4	G	ko:K01222	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Family 4 glycosyl hydrolase
IOLKFBCL_00394	3.87e-162	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
IOLKFBCL_00395	3.44e-138	-	-	-	G	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOLKFBCL_00396	6.09e-110	-	-	-	G	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOLKFBCL_00397	0.0	-	3.2.1.24	GH38	G	ko:K01191	ko00511,map00511	ko00000,ko00001,ko01000,ko04131	Alpha mannosidase, middle domain
IOLKFBCL_00398	1.81e-153	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
IOLKFBCL_00399	2.85e-50	-	-	-	S	-	-	-	Membrane
IOLKFBCL_00400	1.34e-178	-	-	-	-	-	-	-	-
IOLKFBCL_00401	2.07e-187	-	-	-	S	ko:K06999	-	ko00000	Phospholipase/Carboxylesterase
IOLKFBCL_00402	0.0	nhaP	-	-	P	ko:K03316	-	ko00000	Sodium/hydrogen exchanger family
IOLKFBCL_00403	3.4e-106	tadA	3.5.4.1, 3.5.4.33	-	FJ	ko:K01485,ko:K11991	ko00240,ko00330,ko01100,map00240,map00330,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
IOLKFBCL_00404	0.0	-	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Glycosyl hydrolase family 36 N-terminal domain
IOLKFBCL_00405	3.08e-285	-	-	-	GK	-	-	-	ROK family
IOLKFBCL_00406	2.68e-311	-	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
IOLKFBCL_00407	2.7e-208	-	-	-	G	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOLKFBCL_00408	7.15e-197	-	-	-	G	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOLKFBCL_00409	4.38e-10	-	-	-	L	-	-	-	Transposase
IOLKFBCL_00410	0.0	-	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
IOLKFBCL_00411	1.76e-296	ilvA	4.3.1.19	-	E	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Pyridoxal-phosphate dependent enzyme
IOLKFBCL_00412	2.72e-187	cobB2	-	-	K	ko:K12410	-	ko00000,ko01000	Sir2 family
IOLKFBCL_00413	8.53e-117	-	-	-	S	-	-	-	Helix-turn-helix
IOLKFBCL_00414	7.62e-138	-	-	-	E	-	-	-	haloacid dehalogenase-like hydrolase
IOLKFBCL_00415	2.54e-209	-	-	-	G	-	-	-	Phosphoglycerate mutase family
IOLKFBCL_00416	2.31e-296	rutG	-	-	F	ko:K02824,ko:K03458	-	ko00000,ko02000	Permease family
IOLKFBCL_00418	0.0	-	-	-	JKL	-	-	-	helicase superfamily c-terminal domain
IOLKFBCL_00419	5.27e-37	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
IOLKFBCL_00420	3.36e-42	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
IOLKFBCL_00421	0.0	nplT	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain
IOLKFBCL_00422	3.63e-69	pitB	-	-	P	ko:K03306	-	ko00000	Phosphate transporter family
IOLKFBCL_00423	5.51e-147	-	-	-	P	ko:K07220	-	ko00000	Protein of unknown function DUF47
IOLKFBCL_00424	8.95e-142	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
IOLKFBCL_00425	9.07e-283	-	-	-	T	-	-	-	Histidine kinase
IOLKFBCL_00426	2.12e-14	-	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	Cation transporter/ATPase, N-terminus
IOLKFBCL_00427	2.07e-236	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
IOLKFBCL_00428	2.74e-284	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
IOLKFBCL_00429	4.33e-315	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
IOLKFBCL_00430	0.0	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative ATP-dependent DNA helicase recG C-terminal
IOLKFBCL_00431	1.65e-133	-	-	-	S	-	-	-	PIN domain
IOLKFBCL_00432	2.69e-116	-	-	-	K	-	-	-	Helix-turn-helix domain
IOLKFBCL_00434	4.71e-31	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
IOLKFBCL_00435	1.08e-29	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
IOLKFBCL_00436	2.47e-134	-	-	-	-	-	-	-	-
IOLKFBCL_00437	1.67e-259	-	-	-	-	-	-	-	-
IOLKFBCL_00438	2.51e-143	pepE	3.4.13.21	-	E	ko:K05995	-	ko00000,ko01000,ko01002	Peptidase family S51
IOLKFBCL_00439	8.75e-138	pncA	3.5.1.19	-	Q	ko:K08281	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Isochorismatase family
IOLKFBCL_00440	1.37e-95	gloA	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IOLKFBCL_00441	2.06e-208	-	-	-	M	-	-	-	pfam nlp p60
IOLKFBCL_00442	1.25e-203	-	-	-	I	-	-	-	Serine aminopeptidase, S33
IOLKFBCL_00443	4.22e-50	-	-	-	S	-	-	-	Protein of unknown function (DUF2975)
IOLKFBCL_00444	5.21e-41	-	-	-	K	ko:K07727	-	ko00000,ko03000	Cro/C1-type HTH DNA-binding domain
IOLKFBCL_00445	4.08e-305	pbuX	-	-	F	ko:K03458	-	ko00000	Permease family
IOLKFBCL_00446	6.02e-135	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
IOLKFBCL_00447	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
IOLKFBCL_00448	2.11e-85	-	-	-	S	-	-	-	Domain of unknown function (DUF4418)
IOLKFBCL_00449	3.5e-272	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
IOLKFBCL_00450	9.92e-193	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
IOLKFBCL_00451	1.29e-141	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
IOLKFBCL_00452	1.92e-196	-	-	-	S	ko:K07010	-	ko00000,ko01002	Peptidase C26
IOLKFBCL_00453	1.43e-115	-	3.5.4.5	-	F	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	cytidine deaminase activity
IOLKFBCL_00454	7.72e-70	-	-	-	S	-	-	-	SdpI/YhfL protein family
IOLKFBCL_00455	5.99e-143	-	-	-	E	-	-	-	Transglutaminase-like superfamily
IOLKFBCL_00456	6.1e-85	-	-	-	T	-	-	-	PemK-like, MazF-like toxin of type II toxin-antitoxin system
IOLKFBCL_00457	2.55e-65	-	-	-	L	ko:K07473	-	ko00000,ko02048	RelB antitoxin
IOLKFBCL_00458	2.43e-166	-	5.4.2.12	-	G	ko:K15634	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Phosphoglycerate mutase family
IOLKFBCL_00459	8.24e-83	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF948)
IOLKFBCL_00460	2.29e-48	-	-	-	-	-	-	-	-
IOLKFBCL_00461	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IOLKFBCL_00462	6.41e-103	ruvX	-	-	L	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IOLKFBCL_00463	7.79e-263	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IOLKFBCL_00464	2.5e-100	-	3.4.23.43	-	S	ko:K02654	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	Type IV leader peptidase family
IOLKFBCL_00465	7.77e-280	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
IOLKFBCL_00466	0.0	aroB	2.7.1.71, 4.2.3.4	-	H	ko:K01735,ko:K13829	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
IOLKFBCL_00467	2.09e-104	aroQ	4.2.1.10	-	E	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a trans-dehydration via an enolate intermediate
IOLKFBCL_00468	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
IOLKFBCL_00469	0.0	sufB	-	-	O	ko:K09014	-	ko00000	FeS assembly protein SufB
IOLKFBCL_00470	5.91e-299	sufD	-	-	O	ko:K09015	-	ko00000	FeS assembly protein SufD
IOLKFBCL_00471	3.98e-184	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
IOLKFBCL_00472	6.21e-303	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IOLKFBCL_00473	1.18e-132	iscU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
IOLKFBCL_00474	1e-144	-	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
IOLKFBCL_00475	1.79e-306	glgC	2.7.7.27	-	H	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
IOLKFBCL_00476	3.08e-209	spoU2	-	-	J	-	-	-	SpoU rRNA Methylase family
IOLKFBCL_00478	1.28e-183	-	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
IOLKFBCL_00479	9.63e-77	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	Scavenger mRNA decapping enzyme C-term binding
IOLKFBCL_00480	2.38e-272	phoH	-	-	T	ko:K06217	-	ko00000	PhoH-like protein
IOLKFBCL_00481	1.44e-132	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
IOLKFBCL_00482	0.0	corC	-	-	S	-	-	-	CBS domain
IOLKFBCL_00483	1.61e-233	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IOLKFBCL_00484	0.0	fadD2	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme
IOLKFBCL_00485	5.23e-258	pntA	1.6.1.2	-	C	ko:K00324	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	NAD(P) transhydrogenase subunit alpha part 1 K00324
IOLKFBCL_00486	5.05e-58	pntAB	1.6.1.2	-	C	ko:K00324	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	4TM region of pyridine nucleotide transhydrogenase, mitoch
IOLKFBCL_00487	1.43e-308	pntB	1.6.1.2	-	C	ko:K00325	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
IOLKFBCL_00488	1.08e-247	-	-	-	S	ko:K06889	-	ko00000	alpha beta
IOLKFBCL_00489	1.54e-112	ctc	-	-	J	ko:K02897	ko03010,map03010	ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
IOLKFBCL_00490	2.61e-286	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Amino-transferase class IV
IOLKFBCL_00492	2.02e-32	-	-	-	S	-	-	-	Putative phage holin Dp-1
IOLKFBCL_00493	1.43e-74	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
IOLKFBCL_00494	1.1e-26	-	-	-	-	-	-	-	-
IOLKFBCL_00500	4.39e-205	-	-	-	S	-	-	-	cellulase activity
IOLKFBCL_00502	1.16e-180	-	-	-	DNT	-	-	-	domain protein
IOLKFBCL_00505	1.49e-90	-	-	-	-	-	-	-	-
IOLKFBCL_00508	1.93e-84	-	-	-	-	-	-	-	-
IOLKFBCL_00509	2.76e-52	-	-	-	-	-	-	-	-
IOLKFBCL_00510	1.54e-150	-	-	-	S	-	-	-	Phage major capsid protein E
IOLKFBCL_00511	4.44e-69	-	-	-	-	-	-	-	-
IOLKFBCL_00512	1.04e-07	-	-	-	-	-	-	-	-
IOLKFBCL_00513	4.69e-114	-	-	-	-	-	-	-	-
IOLKFBCL_00514	1.34e-265	-	-	-	-	-	-	-	-
IOLKFBCL_00515	0.0	-	-	-	S	-	-	-	Terminase
IOLKFBCL_00524	1.32e-168	tenA	3.5.99.2	-	K	ko:K03707	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
IOLKFBCL_00525	1.5e-102	-	-	-	S	-	-	-	phosphoesterase or phosphohydrolase
IOLKFBCL_00526	1.18e-27	-	-	-	S	-	-	-	Aldo/keto reductase family
IOLKFBCL_00527	2.77e-15	-	-	-	S	-	-	-	Aldo/keto reductase family
IOLKFBCL_00528	3.08e-214	-	-	-	I	-	-	-	alpha/beta hydrolase fold
IOLKFBCL_00529	6.45e-215	CP_1020	-	-	S	-	-	-	zinc ion binding
IOLKFBCL_00530	1.31e-163	-	-	-	S	-	-	-	Plasmid pRiA4b ORF-3-like protein
IOLKFBCL_00531	1.4e-43	rarD	-	-	S	ko:K05786	-	ko00000,ko02000	EamA-like transporter family
IOLKFBCL_00534	1.75e-21	-	-	-	E	-	-	-	Rard protein
IOLKFBCL_00535	1.17e-253	-	-	-	L	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
IOLKFBCL_00536	9.97e-42	-	-	-	S	-	-	-	MazG-like family
IOLKFBCL_00537	1.43e-09	-	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
IOLKFBCL_00538	3.63e-76	CP_1020	-	-	S	-	-	-	zinc ion binding
IOLKFBCL_00539	9.56e-179	-	-	-	-	-	-	-	-
IOLKFBCL_00540	7.59e-122	bcp	1.11.1.15	-	O	ko:K03564	-	ko00000,ko01000	Redoxin
IOLKFBCL_00542	2.96e-206	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
IOLKFBCL_00543	3.44e-201	ylmA	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
IOLKFBCL_00544	6.25e-308	glgA	2.4.1.342	GT4	G	ko:K16148	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000,ko01003	Starch synthase catalytic domain
IOLKFBCL_00545	1.98e-105	-	-	-	-	-	-	-	-
IOLKFBCL_00546	0.0	-	-	-	S	-	-	-	Glycosyl hydrolases related to GH101 family, GH129
IOLKFBCL_00547	0.0	dppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, family 5
IOLKFBCL_00548	0.0	gltD	1.4.1.13, 1.4.1.14	-	C	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
IOLKFBCL_00549	0.0	gltB	1.4.1.13, 1.4.1.14, 1.4.7.1	-	E	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	glutamate synthase NADPH large subunit
IOLKFBCL_00550	7.3e-227	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
IOLKFBCL_00553	2.78e-176	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
IOLKFBCL_00554	1.17e-226	hemN	-	-	H	-	-	-	Involved in the biosynthesis of porphyrin-containing compound
IOLKFBCL_00555	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
IOLKFBCL_00556	6.75e-47	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
IOLKFBCL_00557	1.98e-162	-	-	-	S	-	-	-	UPF0126 domain
IOLKFBCL_00558	2.55e-148	mazG	3.6.1.66	-	S	ko:K02428,ko:K02499	ko00230,map00230	ko00000,ko00001,ko01000,ko03036	Psort location Cytoplasmic, score 8.87
IOLKFBCL_00559	1.38e-130	-	-	-	L	-	-	-	Phage integrase family
IOLKFBCL_00560	9.2e-68	-	-	-	S	-	-	-	Protein of unknown function (DUF4065)
IOLKFBCL_00561	4.56e-21	-	-	-	-	-	-	-	-
IOLKFBCL_00573	3.13e-15	-	-	-	O	-	-	-	COG0330 Membrane protease subunits, stomatin prohibitin homologs
IOLKFBCL_00575	0.000157	wag31	-	-	D	-	-	-	Cell division initiation protein
IOLKFBCL_00576	2.52e-85	-	-	-	L	-	-	-	PDDEXK-like domain of unknown function (DUF3799)
IOLKFBCL_00578	4.21e-07	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-stranded DNA-binding protein
IOLKFBCL_00579	6.26e-42	-	-	-	V	-	-	-	HNH endonuclease
IOLKFBCL_00585	1.02e-65	-	-	-	L	-	-	-	tRNA (guanine-N2-)-methyltransferase activity
IOLKFBCL_00594	3.61e-10	whiB	-	-	K	ko:K18955	-	ko00000,ko03000	Transcription factor WhiB
IOLKFBCL_00605	1.81e-50	-	-	-	-	-	-	-	-
IOLKFBCL_00606	1.45e-32	-	-	-	-	-	-	-	-
IOLKFBCL_00608	1.33e-90	-	-	-	K	ko:K07741	-	ko00000	BRO family, N-terminal domain
IOLKFBCL_00611	8.42e-44	-	-	-	-	-	-	-	-
IOLKFBCL_00616	1.25e-53	-	-	-	L	ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family
IOLKFBCL_00621	4.84e-65	-	-	-	T	-	-	-	Toxic component of a toxin-antitoxin (TA) module
IOLKFBCL_00622	5.17e-46	-	-	-	L	ko:K07473	-	ko00000,ko02048	RelB antitoxin
IOLKFBCL_00631	1.26e-18	-	-	-	K	-	-	-	Helix-turn-helix domain
IOLKFBCL_00633	2.12e-188	-	-	-	K	-	-	-	Bacterial transcriptional regulator
IOLKFBCL_00634	1.49e-170	-	-	-	K	-	-	-	Sugar-specific transcriptional regulator TrmB
IOLKFBCL_00635	1.32e-177	-	-	-	QT	-	-	-	PucR C-terminal helix-turn-helix domain
IOLKFBCL_00636	0.0	-	-	-	-	-	-	-	-
IOLKFBCL_00637	2.25e-190	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Biotin/lipoate A/B protein ligase family
IOLKFBCL_00638	7.91e-19	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
IOLKFBCL_00639	0.0	accC	6.3.4.14, 6.4.1.2, 6.4.1.3	-	I	ko:K11263	ko00061,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase L chain, ATP binding domain protein
IOLKFBCL_00640	0.0	pccB	-	-	I	-	-	-	Carboxyl transferase domain
IOLKFBCL_00641	0.0	fas	-	-	I	ko:K11533	ko00061,ko01100,ko01212,ko04931,map00061,map01100,map01212,map04931	ko00000,ko00001,ko00002,ko01000,ko01004	Beta-ketoacyl synthase, C-terminal domain
IOLKFBCL_00642	2.89e-123	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
IOLKFBCL_00643	2.79e-32	dexB	2.4.1.7, 3.2.1.20, 3.2.1.51, 3.2.1.70, 3.2.1.93, 3.2.1.97	GH101,GH13,GH29,GH31	G	ko:K00690,ko:K01187,ko:K01206,ko:K01215,ko:K01226,ko:K17624	ko00052,ko00500,ko00511,ko01100,map00052,map00500,map00511,map01100	ko00000,ko00001,ko01000,ko04147	hydrolase activity, hydrolyzing O-glycosyl compounds
IOLKFBCL_00645	1.23e-09	-	-	-	-	-	-	-	-
IOLKFBCL_00646	7.07e-103	-	-	-	-	-	-	-	-
IOLKFBCL_00647	0.0	-	-	-	M	-	-	-	Conserved repeat domain
IOLKFBCL_00648	2.13e-128	-	-	-	M	-	-	-	domain protein
IOLKFBCL_00649	9.61e-120	-	-	-	S	-	-	-	AIPR protein
IOLKFBCL_00650	7.59e-108	-	-	-	-	-	-	-	-
IOLKFBCL_00651	2.56e-151	-	-	-	-	-	-	-	-
IOLKFBCL_00652	2.49e-231	-	-	-	L	-	-	-	Transposase
IOLKFBCL_00653	1.08e-120	-	-	-	S	ko:K06999	-	ko00000	Phospholipase/Carboxylesterase
IOLKFBCL_00654	5.15e-247	trmI	2.1.1.219, 2.1.1.220	-	J	ko:K07442	-	ko00000,ko01000,ko03016	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
IOLKFBCL_00655	3.11e-124	sixA	-	-	T	ko:K08296	-	ko00000,ko01000	Phosphoglycerate mutase family
IOLKFBCL_00656	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
IOLKFBCL_00657	6.39e-198	metF	1.5.1.20	-	E	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	Methylenetetrahydrofolate reductase
IOLKFBCL_00658	9.88e-239	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
IOLKFBCL_00659	0.0	glnE	2.7.7.42, 2.7.7.89	-	H	ko:K00982	-	ko00000,ko01000	Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell
IOLKFBCL_00660	4.82e-227	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
IOLKFBCL_00661	3.7e-96	pyrI	-	-	F	ko:K00610	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002	Aspartate carbamoyltransferase regulatory chain, allosteric domain protein
IOLKFBCL_00662	0.0	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
IOLKFBCL_00663	1.74e-223	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the OMP decarboxylase family. Type 2 subfamily
IOLKFBCL_00664	2.74e-203	pyrK	-	-	C	ko:K02823	ko00240,ko01100,map00240,map01100	ko00000,ko00001	Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B
IOLKFBCL_00665	3.42e-233	pyrD	1.3.1.14	-	F	ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
IOLKFBCL_00666	1.33e-159	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
IOLKFBCL_00667	1.08e-39	-	-	-	-	-	-	-	-
IOLKFBCL_00668	1.51e-259	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
IOLKFBCL_00669	2.56e-220	-	-	-	K	-	-	-	Bacterial regulatory helix-turn-helix protein, lysR family
IOLKFBCL_00670	1.3e-87	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter transmembrane region
IOLKFBCL_00671	3.74e-155	-	3.8.1.2	-	S	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
IOLKFBCL_00672	0.0	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IOLKFBCL_00673	3.24e-293	-	2.6.1.1	-	E	ko:K11358	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Psort location Cytoplasmic, score 8.87
IOLKFBCL_00674	1.44e-140	-	-	-	KL	-	-	-	DEAD-like helicases superfamily
IOLKFBCL_00675	8.97e-73	-	-	-	KL	-	-	-	DEAD-like helicases superfamily
IOLKFBCL_00676	1.92e-58	-	-	-	K	-	-	-	Protein of unknown function, DUF488
IOLKFBCL_00678	3.89e-05	-	-	-	S	-	-	-	Virulence protein RhuM family
IOLKFBCL_00679	1.45e-72	-	-	-	S	-	-	-	Virulence protein RhuM family
IOLKFBCL_00681	6.36e-21	-	-	-	S	ko:K09974	-	ko00000	Domain of unknown function (DUF1287)
IOLKFBCL_00682	1.69e-200	-	-	-	-	-	-	-	-
IOLKFBCL_00683	3.4e-98	-	-	-	-	-	-	-	-
IOLKFBCL_00684	4.1e-84	-	-	-	K	-	-	-	Protein of unknown function, DUF488
IOLKFBCL_00685	5.32e-11	-	-	-	-	-	-	-	-
IOLKFBCL_00686	0.0	-	-	-	S	ko:K01421	-	ko00000	YhgE Pip domain protein
IOLKFBCL_00687	0.0	-	-	-	S	ko:K01421	-	ko00000	YhgE Pip domain protein
IOLKFBCL_00688	6.35e-181	nfrA	-	-	C	-	-	-	Nitroreductase family
IOLKFBCL_00689	5.29e-78	-	-	-	S	-	-	-	Protein of unknown function (DUF4235)
IOLKFBCL_00690	3.42e-174	gpm2	3.1.3.73	-	G	ko:K02226	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Phosphoglycerate mutase family
IOLKFBCL_00691	3.71e-316	amyE	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
IOLKFBCL_00692	7.73e-233	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
IOLKFBCL_00693	9.46e-200	msmF	-	-	G	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOLKFBCL_00694	3.69e-195	-	-	-	G	ko:K02026,ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
IOLKFBCL_00695	4.7e-136	-	-	-	S	-	-	-	Protein of unknown function, DUF624
IOLKFBCL_00696	1.65e-93	-	-	-	L	-	-	-	Transposase
IOLKFBCL_00697	0.0	-	-	-	S	ko:K06921	-	ko00000	ATPase domain predominantly from Archaea
IOLKFBCL_00698	0.0	aroP	-	-	E	ko:K03293,ko:K11732	-	ko00000,ko02000	aromatic amino acid transport protein AroP K03293
IOLKFBCL_00699	7.06e-132	-	-	-	K	-	-	-	Transcriptional regulator C-terminal region
IOLKFBCL_00700	1.44e-164	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
IOLKFBCL_00701	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
IOLKFBCL_00702	0.0	-	-	-	E	ko:K03293	-	ko00000	Amino acid permease
IOLKFBCL_00703	2.11e-101	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
IOLKFBCL_00704	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
IOLKFBCL_00705	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter transmembrane region
IOLKFBCL_00706	4.38e-205	-	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
IOLKFBCL_00710	7.49e-243	-	-	-	L	-	-	-	PFAM Integrase catalytic
IOLKFBCL_00711	1.93e-17	-	-	-	-	-	-	-	-
IOLKFBCL_00713	1.22e-18	fabD	2.3.1.39	-	I	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	malonyl CoA-acyl carrier protein transacylase
IOLKFBCL_00714	1.71e-176	-	-	-	Q	-	-	-	Ketoacyl-synthetase C-terminal extension
IOLKFBCL_00715	1.62e-143	-	-	-	Q	-	-	-	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IOLKFBCL_00716	1.04e-233	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
IOLKFBCL_00717	1.4e-145	-	-	-	-	-	-	-	-
IOLKFBCL_00718	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IOLKFBCL_00719	1.37e-58	-	-	-	-	-	-	-	-
IOLKFBCL_00720	8.72e-184	-	-	-	G	ko:K17318	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
IOLKFBCL_00721	2.2e-192	-	-	-	G	ko:K17319	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOLKFBCL_00722	1.39e-194	-	-	-	G	ko:K17320	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOLKFBCL_00723	1.18e-35	-	-	-	S	-	-	-	Unextendable partial coding region
IOLKFBCL_00724	0.0	-	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	MCRA family
IOLKFBCL_00725	1.83e-98	-	-	-	S	-	-	-	Domain of unknown function (DUF4186)
IOLKFBCL_00726	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III alpha subunit
IOLKFBCL_00727	2.75e-166	-	-	-	S	ko:K07058	-	ko00000	Virulence factor BrkB
IOLKFBCL_00728	4e-127	-	-	-	-	-	-	-	-
IOLKFBCL_00729	9.81e-68	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
IOLKFBCL_00730	2.49e-229	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
IOLKFBCL_00731	8.56e-116	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
IOLKFBCL_00732	6.92e-142	-	-	-	V	-	-	-	DivIVA protein
IOLKFBCL_00733	3.18e-56	-	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
IOLKFBCL_00734	2.78e-103	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
IOLKFBCL_00735	1.5e-259	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IOLKFBCL_00736	1.08e-304	dus	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IOLKFBCL_00737	0.0	glyQS	6.1.1.14	-	J	ko:K01880	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of glycine to tRNA(Gly)
IOLKFBCL_00738	3.06e-211	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
IOLKFBCL_00739	0.0	thiC	4.1.99.17	-	H	ko:K03147	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
IOLKFBCL_00740	5.8e-290	-	-	-	O	ko:K13525	ko04141,ko05134,map04141,map05134	ko00000,ko00001,ko00002,ko03019,ko04131,ko04147	AAA domain (Cdc48 subfamily)
IOLKFBCL_00741	1.24e-186	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
IOLKFBCL_00742	2.73e-80	-	-	-	S	-	-	-	Thiamine-binding protein
IOLKFBCL_00743	3.71e-86	-	-	-	T	-	-	-	Histidine kinase
IOLKFBCL_00744	2.35e-23	-	-	-	-	-	-	-	-
IOLKFBCL_00745	0.0	-	-	-	O	ko:K13963	ko05146,map05146	ko00000,ko00001	SERine Proteinase INhibitors
IOLKFBCL_00746	2.17e-243	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
IOLKFBCL_00747	6.47e-303	lacY	-	-	P	ko:K02532	-	ko00000,ko02000	LacY proton/sugar symporter
IOLKFBCL_00748	0.0	fosC	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 32 family
IOLKFBCL_00749	3.12e-177	-	-	-	P	-	-	-	Binding-protein-dependent transport system inner membrane component
IOLKFBCL_00750	1.63e-259	-	-	-	P	-	-	-	NMT1/THI5 like
IOLKFBCL_00751	2.74e-265	-	-	-	F	-	-	-	nucleoside hydrolase
IOLKFBCL_00752	4.53e-196	uppS	2.5.1.31, 2.5.1.86, 2.5.1.88	-	H	ko:K00806,ko:K14215,ko:K21273	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IOLKFBCL_00753	7.4e-145	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
IOLKFBCL_00754	0.0	-	-	-	I	-	-	-	acetylesterase activity
IOLKFBCL_00755	1.14e-294	ispG	1.17.7.1, 1.17.7.3	-	I	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
IOLKFBCL_00756	1.28e-274	dxr	1.1.1.267	-	I	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
IOLKFBCL_00757	0.0	-	-	-	NU	-	-	-	Tfp pilus assembly protein FimV
IOLKFBCL_00759	2.15e-65	-	-	-	S	-	-	-	Protein of unknown function (DUF3052)
IOLKFBCL_00760	4.86e-202	sdrC	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
IOLKFBCL_00761	0.0	-	-	-	S	-	-	-	Zincin-like metallopeptidase
IOLKFBCL_00762	0.0	uvrD2	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
IOLKFBCL_00763	0.0	mphA	-	-	S	-	-	-	Aminoglycoside phosphotransferase
IOLKFBCL_00764	1.13e-44	-	-	-	S	-	-	-	Protein of unknown function (DUF3107)
IOLKFBCL_00765	1.8e-215	PPA1328	3.1.3.97, 3.1.4.57	-	S	ko:K07053,ko:K20859	ko00440,map00440	ko00000,ko00001,ko01000	DNA polymerase alpha chain like domain
IOLKFBCL_00766	1.8e-164	-	-	-	S	-	-	-	Vitamin K epoxide reductase
IOLKFBCL_00767	1.93e-210	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine
IOLKFBCL_00768	1.34e-189	murI	5.1.1.3	-	M	ko:K01776	ko00471,ko01100,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
IOLKFBCL_00769	4.89e-201	-	-	-	S	-	-	-	Patatin-like phospholipase
IOLKFBCL_00770	5.52e-171	hflK	-	-	O	-	-	-	prohibitin homologues
IOLKFBCL_00771	2.37e-143	tcyA/tcyB	-	-	E	ko:K02029,ko:K02424,ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Binding-protein-dependent transport system inner membrane component
IOLKFBCL_00772	4.62e-184	-	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Bacterial periplasmic substrate-binding proteins
IOLKFBCL_00773	1.19e-177	ehuA	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
IOLKFBCL_00774	4.77e-306	-	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Cys/Met metabolism PLP-dependent enzyme
IOLKFBCL_00775	3.12e-293	-	-	-	S	ko:K01436	-	ko00000,ko01000,ko01002	Peptidase dimerisation domain
IOLKFBCL_00776	0.0	-	-	-	E	ko:K01996	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
IOLKFBCL_00777	0.0	-	-	-	E	ko:K01997,ko:K01998	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid transport system / permease component
IOLKFBCL_00778	1.45e-280	-	-	-	E	ko:K01999	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Receptor family ligand binding region
IOLKFBCL_00779	5.85e-253	-	4.1.1.37	-	H	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Uroporphyrinogen decarboxylase (URO-D)
IOLKFBCL_00780	4.46e-185	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IOLKFBCL_00781	2.84e-199	-	-	-	E	-	-	-	Glyoxalase-like domain
IOLKFBCL_00782	2.28e-57	-	-	-	O	-	-	-	Glutaredoxin
IOLKFBCL_00783	9.3e-291	metC1	4.4.1.8	-	E	ko:K01760	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Cys/Met metabolism PLP-dependent enzyme
IOLKFBCL_00784	1.1e-165	glnH	-	-	ET	ko:K02030,ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
IOLKFBCL_00785	2.19e-144	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ATP binding protein of ABC transporter for glutamate aspartate K02028
IOLKFBCL_00786	1.31e-142	glnP	-	-	E	ko:K02029,ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOLKFBCL_00787	2.04e-125	glnP2	-	-	E	ko:K02029	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOLKFBCL_00788	3.56e-152	-	-	-	S	ko:K06999	-	ko00000	Phospholipase/Carboxylesterase
IOLKFBCL_00789	0.0	tetM	-	-	J	ko:K18220	-	br01600,ko00000,ko01504	Elongation factor G, domain IV
IOLKFBCL_00790	3.16e-169	-	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Exonuclease, DNA polymerase III, epsilon subunit family
IOLKFBCL_00792	4.38e-134	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
IOLKFBCL_00793	2.09e-214	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
IOLKFBCL_00794	0.0	carB	6.3.5.5	-	EF	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase large chain, oligomerisation domain
IOLKFBCL_00795	1.05e-303	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarA family
IOLKFBCL_00796	1.72e-122	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IOLKFBCL_00797	7.09e-136	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IOLKFBCL_00798	1.52e-145	-	-	-	V	ko:K02068	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
IOLKFBCL_00799	4.66e-164	-	-	-	V	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
IOLKFBCL_00800	0.0	-	-	-	G	-	-	-	Glycosyl hydrolase family 20, domain 2
IOLKFBCL_00801	7.45e-257	mrp	-	-	D	ko:K03593	-	ko00000,ko03029,ko03036	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
IOLKFBCL_00802	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IOLKFBCL_00803	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeat
IOLKFBCL_00804	0.0	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IOLKFBCL_00805	1.2e-178	-	-	-	P	ko:K16784	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
IOLKFBCL_00806	1.25e-284	-	-	-	E	-	-	-	Aminotransferase class I and II
IOLKFBCL_00807	1.56e-179	ppgK	2.7.1.2, 2.7.1.63	-	GK	ko:K00845,ko:K00886	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
IOLKFBCL_00808	5.22e-257	-	-	-	S	-	-	-	Glycosyltransferase, group 2 family protein
IOLKFBCL_00809	2.87e-138	-	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
IOLKFBCL_00810	0.0	-	-	-	GP	ko:K16785,ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
IOLKFBCL_00811	7.75e-62	-	-	-	J	ko:K07574	-	ko00000,ko03009	CRS1_YhbY
IOLKFBCL_00812	8.24e-71	-	-	-	S	ko:K08972	-	ko00000	Mycobacterial 4 TMS phage holin, superfamily IV
IOLKFBCL_00813	6.5e-106	-	-	-	J	-	-	-	TM2 domain
IOLKFBCL_00814	9.11e-236	-	-	-	EH	-	-	-	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
IOLKFBCL_00815	8.57e-316	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
IOLKFBCL_00816	1.92e-314	rarA	-	-	L	ko:K07478	-	ko00000	Recombination factor protein RarA
IOLKFBCL_00817	0.0	-	-	-	L	-	-	-	DEAD DEAH box helicase
IOLKFBCL_00818	7.07e-250	-	-	-	S	-	-	-	Polyphosphate kinase 2 (PPK2)
IOLKFBCL_00819	4.97e-31	-	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	5'-nucleotidase, C-terminal domain
IOLKFBCL_00820	0.0	-	-	-	I	-	-	-	PAP2 superfamily
IOLKFBCL_00821	3.82e-238	gluD	-	-	E	ko:K10007	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOLKFBCL_00822	3.05e-137	gluC	-	-	E	ko:K10006	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOLKFBCL_00823	1.98e-194	gluB	-	-	ET	ko:K10005	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
IOLKFBCL_00824	7.84e-181	gluA	-	-	E	ko:K10008	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding protein of ABC transporter for glutamate K02028
IOLKFBCL_00825	3.55e-232	-	-	-	S	-	-	-	Protein of unknown function (DUF559)
IOLKFBCL_00826	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
IOLKFBCL_00827	0.0	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Histidyl-tRNA synthetase
IOLKFBCL_00828	0.0	-	-	-	S	-	-	-	Domain of Unknown Function (DUF349)
IOLKFBCL_00829	0.0	-	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	5'-nucleotidase, C-terminal domain
IOLKFBCL_00830	3.69e-181	-	3.5.2.10	-	S	ko:K01470	ko00330,map00330	ko00000,ko00001,ko01000	Creatinine amidohydrolase
IOLKFBCL_00831	1.82e-316	proP	-	-	EGP	ko:K03762	-	ko00000,ko02000	Sugar (and other) transporter
IOLKFBCL_00832	0.0	-	-	-	QT	-	-	-	Purine catabolism regulatory protein-like family
IOLKFBCL_00833	0.0	codA	3.5.4.1, 3.5.4.21	-	F	ko:K01485,ko:K03365	ko00240,ko00330,ko01100,map00240,map00330,map01100	ko00000,ko00001,ko01000	Amidohydrolase family
IOLKFBCL_00834	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	ATPase family associated with various cellular activities (AAA)
IOLKFBCL_00835	1.67e-223	uspA	-	-	T	-	-	-	Belongs to the universal stress protein A family
IOLKFBCL_00836	3.16e-247	-	-	-	S	-	-	-	Protein of unknown function (DUF3027)
IOLKFBCL_00837	1.01e-86	cspB	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
IOLKFBCL_00838	0.0	phoR	2.7.13.3	-	T	ko:K02484	-	ko00000,ko01000,ko01001,ko02022	ATPase histidine kinase DNA gyrase B HSP90 domain protein
IOLKFBCL_00839	2.26e-170	phoP	-	-	KT	ko:K02483	-	ko00000,ko02022	Response regulator receiver domain protein
IOLKFBCL_00840	5.32e-113	-	-	-	-	-	-	-	-
IOLKFBCL_00841	2.78e-55	-	-	-	S	-	-	-	Proteins of 100 residues with WXG
IOLKFBCL_00842	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
IOLKFBCL_00843	2.18e-51	cspA	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
IOLKFBCL_00844	8.52e-95	-	-	-	S	-	-	-	LytR cell envelope-related transcriptional attenuator
IOLKFBCL_00845	1.02e-171	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
IOLKFBCL_00846	6.79e-249	moxR	-	-	S	ko:K03924	-	ko00000,ko01000	ATPase family associated with various cellular activities (AAA)
IOLKFBCL_00847	1.04e-219	-	-	-	S	-	-	-	Protein of unknown function DUF58
IOLKFBCL_00848	3.68e-117	-	-	-	-	-	-	-	-
IOLKFBCL_00849	1.51e-237	-	-	-	S	ko:K07114	-	ko00000,ko02000	von Willebrand factor (vWF) type A domain
IOLKFBCL_00850	7.86e-224	-	-	-	S	ko:K07114	-	ko00000,ko02000	von Willebrand factor (vWF) type A domain
IOLKFBCL_00851	3.86e-90	-	-	-	-	-	-	-	-
IOLKFBCL_00852	1.33e-69	-	-	-	-	-	-	-	-
IOLKFBCL_00853	0.0	-	-	-	S	-	-	-	PGAP1-like protein
IOLKFBCL_00854	0.0	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Adenylosuccinate lyase C-terminal
IOLKFBCL_00855	0.0	-	-	-	S	-	-	-	Lysylphosphatidylglycerol synthase TM region
IOLKFBCL_00856	3.31e-57	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Belongs to the bacterial histone-like protein family
IOLKFBCL_00859	2.38e-77	-	-	-	-	-	-	-	-
IOLKFBCL_00860	5.58e-317	-	-	-	L	-	-	-	PFAM Integrase catalytic
IOLKFBCL_00861	2.33e-49	-	-	-	L	ko:K07483	-	ko00000	Integrase core domain
IOLKFBCL_00862	7.6e-53	-	-	-	L	ko:K07483	-	ko00000	Psort location Cytoplasmic, score 8.87
IOLKFBCL_00863	2.76e-68	-	-	-	FG	-	-	-	bis(5'-adenosyl)-triphosphatase activity
IOLKFBCL_00864	3.48e-218	uxaC	5.3.1.12	-	G	ko:K01812	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Glucuronate isomerase
IOLKFBCL_00865	5.93e-242	mtlD	1.1.1.57, 1.1.1.58	-	G	ko:K00040,ko:K00041	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Mannitol dehydrogenase C-terminal domain
IOLKFBCL_00866	1.82e-295	-	4.2.1.8	-	M	ko:K08323	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	mandelate racemase muconate lactonizing
IOLKFBCL_00867	2.21e-286	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
IOLKFBCL_00868	4.05e-89	-	-	-	K	ko:K02529,ko:K05499	-	ko00000,ko03000	Periplasmic binding proteins and sugar binding domain of LacI family
IOLKFBCL_00869	6.63e-68	-	-	-	K	ko:K02529,ko:K05499	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
IOLKFBCL_00870	2.82e-122	-	-	-	G	ko:K16210	-	ko00000,ko02000	MFS/sugar transport protein
IOLKFBCL_00871	0.0	-	-	-	L	-	-	-	PFAM Integrase catalytic
IOLKFBCL_00872	1.12e-182	uxuT	-	-	G	ko:K03292,ko:K16210	-	ko00000,ko02000	MFS/sugar transport protein
IOLKFBCL_00873	7.51e-16	-	-	-	L	-	-	-	Helix-turn-helix domain
IOLKFBCL_00874	7.83e-83	-	-	-	L	-	-	-	PFAM Integrase catalytic
IOLKFBCL_00875	2.28e-58	-	-	-	L	-	-	-	Transposase, Mutator family
IOLKFBCL_00876	8.14e-201	-	-	-	I	-	-	-	type I phosphodiesterase nucleotide pyrophosphatase
IOLKFBCL_00877	4.28e-254	-	-	-	E	ko:K02052	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
IOLKFBCL_00878	9.99e-198	-	-	-	U	ko:K02053	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOLKFBCL_00879	4.24e-195	-	-	-	U	ko:K02054	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOLKFBCL_00880	1.28e-256	-	-	-	P	ko:K02055	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
IOLKFBCL_00881	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IOLKFBCL_00882	9.15e-308	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I II
IOLKFBCL_00883	8.6e-206	nanA	4.1.3.3, 4.3.3.7	-	EM	ko:K01639,ko:K01714	ko00261,ko00300,ko00520,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map00520,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Dihydrodipicolinate synthetase family
IOLKFBCL_00884	5.48e-181	oppF	-	-	E	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
IOLKFBCL_00885	0.0	oppCD2	-	-	EP	ko:K02031,ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Oligopeptide/dipeptide transporter, C-terminal region
IOLKFBCL_00886	9.16e-215	oppB6	-	-	EP	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOLKFBCL_00887	0.0	oppA7	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
IOLKFBCL_00888	0.0	neu	3.2.1.18	GH33	G	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	ko00000,ko00001,ko01000,ko02042	BNR repeat-like domain
IOLKFBCL_00889	1.59e-147	nanE	5.1.3.9	-	G	ko:K01788	ko00520,map00520	ko00000,ko00001,ko01000	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
IOLKFBCL_00890	4.56e-153	-	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
IOLKFBCL_00891	4.06e-181	-	-	-	L	-	-	-	Domain of unknown function (DUF4862)
IOLKFBCL_00892	9.68e-138	-	-	-	K	-	-	-	FCD
IOLKFBCL_00893	3.08e-222	-	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
IOLKFBCL_00894	7.25e-206	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IOLKFBCL_00895	1.73e-16	iunH2	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Inosine-uridine preferring nucleoside hydrolase
IOLKFBCL_00896	5.61e-240	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
IOLKFBCL_00897	7.79e-211	rihB	3.2.2.1, 3.2.2.8	-	F	ko:K01239,ko:K01250,ko:K10213	ko00230,ko00240,ko00760,ko01100,map00230,map00240,map00760,map01100	ko00000,ko00001,ko01000	Inosine-uridine preferring nucleoside hydrolase
IOLKFBCL_00898	3.06e-173	rbsR	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
IOLKFBCL_00899	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter transmembrane region
IOLKFBCL_00900	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
IOLKFBCL_00901	0.0	-	3.1.4.52	-	T	ko:K14051	ko02024,ko02026,map02024,map02026	ko00000,ko00001,ko01000	Putative diguanylate phosphodiesterase
IOLKFBCL_00902	1.54e-144	-	-	-	S	-	-	-	Domain of unknown function (DUF4956)
IOLKFBCL_00903	3.07e-200	-	-	-	P	-	-	-	VTC domain
IOLKFBCL_00904	0.0	-	-	-	M	ko:K06330	-	ko00000	CotH kinase protein
IOLKFBCL_00905	0.0	-	-	-	S	ko:K21012	ko02025,map02025	ko00000,ko00001	Putative exopolysaccharide Exporter (EPS-E)
IOLKFBCL_00906	0.0	-	-	GT4	M	ko:K21011	ko02025,map02025	ko00000,ko00001,ko01003	Domain of unknown function (DUF3492)
IOLKFBCL_00907	0.0	-	-	-	S	-	-	-	Uncharacterised protein conserved in bacteria (DUF2194)
IOLKFBCL_00908	9.11e-208	-	-	-	-	-	-	-	-
IOLKFBCL_00909	0.0	-	5.1.3.2	-	GM	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	ADP-glyceromanno-heptose 6-epimerase activity
IOLKFBCL_00911	0.0	bglB	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Glycosyl hydrolase family 3 N-terminal domain protein
IOLKFBCL_00912	8.03e-110	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
IOLKFBCL_00913	1.46e-50	-	-	-	-	-	-	-	-
IOLKFBCL_00914	1.5e-296	-	3.2.1.4, 3.2.1.58	GH5,GH9	G	ko:K01179,ko:K01210	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 5 (cellulase A) family
IOLKFBCL_00915	2.55e-91	-	-	-	S	-	-	-	Nucleotidyltransferase substrate binding protein like
IOLKFBCL_00916	2.9e-61	-	-	-	S	-	-	-	Nucleotidyltransferase domain
IOLKFBCL_00917	2.14e-76	bgl2	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Fibronectin type III-like domain
IOLKFBCL_00918	0.0	egtA	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Glutamate-cysteine ligase family 2(GCS2)
IOLKFBCL_00919	0.0	hgdC	-	-	I	-	-	-	CoA enzyme activase uncharacterised domain (DUF2229)
IOLKFBCL_00920	1.25e-183	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IOLKFBCL_00921	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Anaerobic ribonucleoside-triphosphate reductase
IOLKFBCL_00922	0.0	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IOLKFBCL_00923	6.67e-58	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IOLKFBCL_00924	8.95e-297	-	-	-	S	-	-	-	peptidyl-serine autophosphorylation
IOLKFBCL_00925	1.4e-117	ywrO	-	-	S	-	-	-	Flavodoxin-like fold
IOLKFBCL_00926	0.0	-	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme
IOLKFBCL_00927	8.33e-99	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase
IOLKFBCL_00929	1.25e-245	-	-	-	S	ko:K18353	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01504	Endonuclease/Exonuclease/phosphatase family
IOLKFBCL_00930	4.21e-15	ppx1	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	Ppx/GppA phosphatase family
IOLKFBCL_00931	1.36e-10	ppx1	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	Ppx/GppA phosphatase family
IOLKFBCL_00932	1.14e-294	aspB	2.6.1.1, 2.6.1.2, 2.6.1.66	-	E	ko:K00812,ko:K14260	ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase class-V
IOLKFBCL_00933	1.61e-252	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
IOLKFBCL_00934	2.73e-109	vsr	-	-	L	ko:K07458	-	ko00000,ko01000,ko03400	May nick specific sequences that contain T G mispairs resulting from m5C-deamination
IOLKFBCL_00935	2.01e-47	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
IOLKFBCL_00936	4.04e-46	-	-	-	-	-	-	-	-
IOLKFBCL_00937	2.65e-103	-	-	-	S	-	-	-	PFAM Uncharacterised protein family UPF0150
IOLKFBCL_00938	0.0	-	-	-	KL	-	-	-	Psort location Cytoplasmic, score 8.87
IOLKFBCL_00939	1.72e-268	-	-	-	K	-	-	-	WYL domain
IOLKFBCL_00940	1.65e-223	dapD	2.3.1.117	-	E	ko:K00674	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA
IOLKFBCL_00941	3.68e-314	gltA	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Citrate synthase, C-terminal domain
IOLKFBCL_00942	1.07e-193	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine aminopeptidase
IOLKFBCL_00943	3.5e-184	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
IOLKFBCL_00944	0.0	pepO	3.4.24.11, 3.4.24.71	-	O	ko:K01389,ko:K01415,ko:K07386	ko04614,ko04640,ko04974,ko05010,map04614,map04640,map04974,map05010	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	Peptidase family M13
IOLKFBCL_00945	1.7e-70	ssb2	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-strand binding protein family
IOLKFBCL_00946	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
IOLKFBCL_00947	9.23e-30	-	-	-	NU	-	-	-	Tfp pilus assembly protein FimV
IOLKFBCL_00948	5.14e-43	-	-	-	S	ko:K06990	-	ko00000,ko04812	AMMECR1
IOLKFBCL_00949	3.44e-77	-	-	-	S	ko:K06990	-	ko00000,ko04812	AMMECR1
IOLKFBCL_00950	0.0	-	-	-	L	-	-	-	PIF1-like helicase
IOLKFBCL_00951	3.99e-149	orn	-	-	L	ko:K13288	ko03008,map03008	ko00000,ko00001,ko01000,ko03009,ko03019	3'-to-5' exoribonuclease specific for small oligoribonucleotides
IOLKFBCL_00952	0.0	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
IOLKFBCL_00953	2.46e-274	rfe	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	Glycosyl transferase family 4
IOLKFBCL_00954	1.68e-154	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Belongs to the SUA5 family
IOLKFBCL_00955	1.86e-128	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Bacterial transferase hexapeptide repeat protein
IOLKFBCL_00956	8.01e-227	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
IOLKFBCL_00957	1.59e-244	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IOLKFBCL_00958	6.44e-49	rpmE	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the 23S rRNA
IOLKFBCL_00960	5.56e-287	xylR	-	-	GK	-	-	-	ROK family
IOLKFBCL_00961	0.0	xylB	2.7.1.17	-	G	ko:K00854	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	FGGY family of carbohydrate kinases, C-terminal domain
IOLKFBCL_00962	1.76e-40	-	-	-	-	-	-	-	-
IOLKFBCL_00963	2.67e-49	-	-	-	-	-	-	-	-
IOLKFBCL_00964	1.59e-221	-	-	-	L	-	-	-	Transposase, Mutator family
IOLKFBCL_00966	0.0	-	-	-	G	-	-	-	Psort location Cytoplasmic, score 8.87
IOLKFBCL_00967	2.05e-139	maa	2.3.1.18, 2.3.1.79	-	S	ko:K00633,ko:K00661	-	ko00000,ko01000	Bacterial transferase hexapeptide repeat protein
IOLKFBCL_00968	0.0	-	3.2.1.37, 3.2.1.55	GH43,GH51	G	ko:K01198,ko:K01209	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
IOLKFBCL_00969	0.0	-	3.2.1.37	GH43	G	ko:K01198	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
IOLKFBCL_00970	1.41e-176	-	-	-	P	ko:K02026,ko:K10119,ko:K17243	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOLKFBCL_00971	1.13e-188	-	-	-	U	ko:K02025,ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOLKFBCL_00972	9.34e-263	-	-	-	G	ko:K02027,ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter periplasmic binding protein YcjN precursor K02027
IOLKFBCL_00973	2.08e-241	-	-	-	K	ko:K02529,ko:K17640	-	ko00000,ko03000	Bacterial regulatory proteins, lacI family
IOLKFBCL_00974	8.04e-300	-	-	-	C	-	-	-	Iron-containing alcohol dehydrogenase
IOLKFBCL_00975	0.0	xylA	5.3.1.5	-	G	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko01000	Belongs to the xylose isomerase family
IOLKFBCL_00976	2.82e-44	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
IOLKFBCL_00977	3.78e-28	-	-	-	U	-	-	-	Drug resistance MFS transporter, drug H antiporter-2 family
IOLKFBCL_00978	5.51e-199	-	-	-	-	-	-	-	-
IOLKFBCL_00979	3.05e-95	fms	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
IOLKFBCL_00980	1.08e-209	dkg	-	-	S	-	-	-	Oxidoreductase, aldo keto reductase family protein
IOLKFBCL_00981	9.99e-176	-	-	-	EGP	-	-	-	Major facilitator superfamily
IOLKFBCL_00982	1.53e-118	-	-	-	K	-	-	-	Winged helix DNA-binding domain
IOLKFBCL_00983	1.37e-54	-	-	-	-	-	-	-	-
IOLKFBCL_00984	3.88e-253	-	-	-	U	ko:K10547	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid transport system / permease component
IOLKFBCL_00985	0.0	araG	3.6.3.17	-	G	ko:K10548	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
IOLKFBCL_00986	1.09e-274	-	-	-	G	ko:K10546	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein domain
IOLKFBCL_00987	2.47e-273	-	-	-	GK	-	-	-	ROK family
IOLKFBCL_00988	2.49e-197	-	3.6.3.17	-	G	ko:K02056,ko:K10545	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
IOLKFBCL_00989	1.96e-224	glkA	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
IOLKFBCL_00991	0.0	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
IOLKFBCL_00993	8.16e-78	-	-	-	K	-	-	-	Virulence activator alpha C-term
IOLKFBCL_00994	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
IOLKFBCL_00995	3.4e-120	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
IOLKFBCL_00996	2.41e-46	-	-	-	L	-	-	-	Transposase, Mutator family
IOLKFBCL_00998	7.47e-262	-	-	-	EGP	-	-	-	Major facilitator Superfamily
IOLKFBCL_00999	0.0	yjjK	-	-	S	-	-	-	ATP-binding cassette protein, ChvD family
IOLKFBCL_01000	2.56e-217	tesB	-	-	I	ko:K10805	ko01040,map01040	ko00000,ko00001,ko01000,ko01004	Thioesterase-like superfamily
IOLKFBCL_01001	3.16e-119	-	-	-	S	-	-	-	Protein of unknown function (DUF3180)
IOLKFBCL_01002	0.0	folK	2.7.6.3, 4.1.2.25	-	H	ko:K00950,ko:K13940	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
IOLKFBCL_01003	1.45e-202	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
IOLKFBCL_01004	2.43e-137	folE	3.5.4.16	-	H	ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase
IOLKFBCL_01006	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IOLKFBCL_01007	2.03e-124	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
IOLKFBCL_01008	1.58e-264	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K00760,ko:K04075	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
IOLKFBCL_01009	0.0	dacB	3.4.16.4	-	M	ko:K07259	ko00550,map00550	ko00000,ko00001,ko01000,ko01002,ko01011	D-Ala-D-Ala carboxypeptidase 3 (S13) family
IOLKFBCL_01010	0.0	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
IOLKFBCL_01011	2.36e-206	natA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
IOLKFBCL_01012	1.33e-293	-	-	-	M	-	-	-	Glycosyl transferase family 21
IOLKFBCL_01013	0.0	-	-	-	S	-	-	-	AI-2E family transporter
IOLKFBCL_01014	3.82e-227	-	-	-	M	-	-	-	Glycosyltransferase like family 2
IOLKFBCL_01015	3.91e-267	fucO	1.1.1.77, 1.1.99.37, 1.2.98.1	-	C	ko:K00048,ko:K17067	ko00625,ko00630,ko00640,ko00680,ko01120,ko01200,map00625,map00630,map00640,map00680,map01120,map01200	ko00000,ko00001,ko01000	Iron-containing alcohol dehydrogenase
IOLKFBCL_01016	0.0	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	Mycolic acid cyclopropane synthetase
IOLKFBCL_01019	5.63e-255	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
IOLKFBCL_01020	8.11e-202	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
IOLKFBCL_01022	1.88e-42	-	-	-	-	-	-	-	-
IOLKFBCL_01026	5.42e-238	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Divergent AAA domain protein
IOLKFBCL_01028	9.2e-22	-	-	-	M	-	-	-	Glycosyltransferase like family 2
IOLKFBCL_01030	9.26e-45	-	-	-	-	-	-	-	-
IOLKFBCL_01031	1.54e-83	-	-	-	V	-	-	-	Abi-like protein
IOLKFBCL_01032	1.76e-12	-	-	-	V	-	-	-	Abi-like protein
IOLKFBCL_01033	2.81e-60	-	-	-	P	-	-	-	Major facilitator superfamily
IOLKFBCL_01035	8.36e-107	-	-	-	M	-	-	-	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
IOLKFBCL_01037	0.0	-	-	-	U	ko:K03205	ko03070,map03070	ko00000,ko00001,ko00002,ko02044	Type IV secretory system Conjugative DNA transfer
IOLKFBCL_01039	1.71e-65	-	-	-	-	-	-	-	-
IOLKFBCL_01040	8.49e-57	-	-	-	S	-	-	-	Antirestriction protein (ArdA)
IOLKFBCL_01041	3.01e-75	-	-	-	L	ko:K07493	-	ko00000	PFAM Transposase, Mutator family
IOLKFBCL_01042	8.17e-22	-	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	3-Oxoacyl- acyl-carrier-protein (ACP) synthase III C terminal
IOLKFBCL_01043	3.47e-229	-	-	-	L	-	-	-	Transposase, Mutator family
IOLKFBCL_01044	3.44e-302	-	-	-	L	-	-	-	Transposase
IOLKFBCL_01045	4.62e-62	-	-	-	L	-	-	-	Transposase
IOLKFBCL_01046	1.27e-74	-	-	-	L	-	-	-	Transposase
IOLKFBCL_01047	4.25e-09	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
IOLKFBCL_01048	2.61e-197	-	-	-	S	-	-	-	Aldo/keto reductase family
IOLKFBCL_01049	1.03e-197	-	2.7.1.17	-	G	ko:K00854	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	FGGY family of carbohydrate kinases, N-terminal domain
IOLKFBCL_01050	0.0	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
IOLKFBCL_01051	1.1e-279	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
IOLKFBCL_01052	2.75e-143	hisB	3.1.3.15, 4.2.1.19	-	E	ko:K01089,ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Imidazoleglycerol-phosphate dehydratase
IOLKFBCL_01053	4.01e-143	-	-	-	-	-	-	-	-
IOLKFBCL_01054	1.77e-156	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
IOLKFBCL_01055	1.96e-166	hisA	5.3.1.16, 5.3.1.24	-	E	ko:K01814,ko:K01817	ko00340,ko00400,ko01100,ko01110,ko01130,ko01230,map00340,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Histidine biosynthesis protein
IOLKFBCL_01056	3.61e-25	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2252)
IOLKFBCL_01057	0.0	glnA2	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
IOLKFBCL_01058	4.72e-241	-	-	-	EGP	ko:K18567,ko:K19577	-	ko00000,ko02000	Major Facilitator Superfamily
IOLKFBCL_01059	5.43e-176	appC	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOLKFBCL_01060	3.25e-227	-	-	-	EP	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOLKFBCL_01061	0.0	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
IOLKFBCL_01062	0.0	-	-	-	P	ko:K02031,ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
IOLKFBCL_01063	4.56e-221	-	-	-	M	-	-	-	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
IOLKFBCL_01064	0.0	hrpA	3.6.4.13	-	L	ko:K03578	-	ko00000,ko01000	Helicase associated domain (HA2) Add an annotation
IOLKFBCL_01065	3.86e-157	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase (PrmA)
IOLKFBCL_01066	0.0	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IOLKFBCL_01067	4.62e-225	ldh	1.1.1.27, 1.1.1.37	-	C	ko:K00016,ko:K00024	ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
IOLKFBCL_01068	6.04e-201	czcD	-	-	P	ko:K16264	-	ko00000,ko02000	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IOLKFBCL_01069	2.78e-166	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IOLKFBCL_01070	2.32e-70	-	-	-	M	-	-	-	Lysin motif
IOLKFBCL_01071	8.78e-64	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
IOLKFBCL_01072	1.31e-289	serA	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
IOLKFBCL_01073	0.0	-	-	-	L	-	-	-	DNA helicase
IOLKFBCL_01074	3.86e-119	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
IOLKFBCL_01075	9.64e-249	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
IOLKFBCL_01076	2.74e-96	-	-	-	D	-	-	-	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
IOLKFBCL_01077	0.0	ftsI	3.4.16.4	-	M	ko:K03587	ko00550,ko01501,map00550,map01501	ko00000,ko00001,ko01000,ko01011,ko03036	Penicillin-binding protein, transpeptidase domain protein
IOLKFBCL_01078	5.87e-197	-	-	-	M	-	-	-	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IOLKFBCL_01079	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
IOLKFBCL_01080	7.84e-264	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IOLKFBCL_01081	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IOLKFBCL_01082	6.74e-286	ftsW	2.4.1.227	GT28	D	ko:K02563,ko:K03588	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011,ko02000,ko03036	Belongs to the SEDS family
IOLKFBCL_01083	5.23e-277	murG	2.4.1.227, 6.3.2.8	GT28	M	ko:K01924,ko:K02563	ko00471,ko00550,ko01100,ko01502,ko04112,map00471,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IOLKFBCL_01084	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
IOLKFBCL_01085	3.4e-235	ftsQ	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein FtsQ
IOLKFBCL_01087	1.85e-60	-	-	-	L	ko:K07483	-	ko00000	Transposase
IOLKFBCL_01088	2.65e-185	tnp3521a2	-	-	L	-	-	-	Integrase core domain
IOLKFBCL_01089	6.13e-138	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
IOLKFBCL_01090	3.46e-108	-	-	-	V	-	-	-	ABC-2 family transporter protein
IOLKFBCL_01091	2.98e-46	-	-	-	S	ko:K09136	-	ko00000,ko03009	YcaO cyclodehydratase, ATP-ad Mg2+-binding
IOLKFBCL_01092	6.91e-45	tnp3521a2	-	-	L	-	-	-	Integrase core domain
IOLKFBCL_01093	4.49e-259	-	-	-	L	ko:K03733	-	ko00000,ko03036	Phage integrase, N-terminal SAM-like domain
IOLKFBCL_01094	3.08e-244	-	-	-	L	-	-	-	Phage integrase family
IOLKFBCL_01095	1.94e-287	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
IOLKFBCL_01096	1.73e-45	tnp3521a2	-	-	L	-	-	-	Integrase core domain
IOLKFBCL_01097	2.21e-157	-	-	-	L	ko:K07496	-	ko00000	Psort location Cytoplasmic, score 8.87
IOLKFBCL_01098	9.95e-233	-	-	-	S	ko:K07133	-	ko00000	Domain of unknown function (DUF4143)
IOLKFBCL_01101	6.64e-19	-	-	-	EQ	-	-	-	Hydantoinase/oxoprolinase
IOLKFBCL_01102	9.77e-35	-	-	-	EQ	-	-	-	Hydantoinase/oxoprolinase N-terminal region
IOLKFBCL_01103	7.31e-28	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
IOLKFBCL_01104	1.11e-163	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
IOLKFBCL_01105	1.35e-82	-	-	-	S	-	-	-	HicB_like antitoxin of bacterial toxin-antitoxin system
IOLKFBCL_01106	6.8e-110	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
IOLKFBCL_01107	0.0	-	3.2.1.24	GH38	G	ko:K01191	ko00511,map00511	ko00000,ko00001,ko01000,ko04131	Alpha mannosidase, middle domain
IOLKFBCL_01108	0.0	-	3.2.1.24	GH38	G	ko:K01191	ko00511,map00511	ko00000,ko00001,ko01000,ko04131	Alpha mannosidase, middle domain
IOLKFBCL_01109	0.0	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
IOLKFBCL_01110	3.78e-221	dppB	-	-	EP	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOLKFBCL_01111	9.32e-231	dppC	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOLKFBCL_01112	0.0	-	-	-	P	ko:K02031,ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
IOLKFBCL_01113	3.87e-208	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
IOLKFBCL_01114	8.39e-299	-	-	-	G	-	-	-	N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)
IOLKFBCL_01115	0.0	-	-	-	S	ko:K09704	-	ko00000	Metal-independent alpha-mannosidase (GH125)
IOLKFBCL_01116	1.66e-216	-	2.7.1.4	-	G	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
IOLKFBCL_01117	2.83e-282	-	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
IOLKFBCL_01118	7.17e-205	-	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
IOLKFBCL_01119	6.36e-257	-	-	-	GK	-	-	-	ROK family
IOLKFBCL_01120	3.84e-192	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
IOLKFBCL_01121	4.16e-297	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Amidohydrolase family
IOLKFBCL_01122	1.83e-253	-	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
IOLKFBCL_01123	1.18e-139	-	-	-	U	ko:K02025,ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOLKFBCL_01124	5.24e-158	-	-	-	G	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport systems inner membrane component
IOLKFBCL_01127	1.98e-227	-	3.2.1.51	GH29	G	ko:K01206	ko00511,map00511	ko00000,ko00001,ko01000,ko04147	Alpha-L-fucosidase
IOLKFBCL_01128	1.47e-98	-	-	-	F	-	-	-	NUDIX domain
IOLKFBCL_01129	0.0	pepP	3.4.11.9	-	E	ko:K01262	-	ko00000,ko01000,ko01002	Aminopeptidase P, N-terminal domain
IOLKFBCL_01130	1.3e-202	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
IOLKFBCL_01131	0.0	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Mur ligase middle domain
IOLKFBCL_01132	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
IOLKFBCL_01133	1.36e-243	-	-	-	V	-	-	-	Acetyltransferase (GNAT) domain
IOLKFBCL_01134	0.0	murE	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IOLKFBCL_01135	1.54e-172	sigH	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
IOLKFBCL_01136	6.7e-72	-	-	-	-	-	-	-	-
IOLKFBCL_01137	3.18e-238	-	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
IOLKFBCL_01138	4.72e-242	-	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
IOLKFBCL_01139	1.37e-227	ispH	1.17.7.4	-	IM	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
IOLKFBCL_01140	5.31e-115	ybaK	-	-	J	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IOLKFBCL_01141	1.05e-253	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
IOLKFBCL_01142	1.82e-171	-	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Thiamin pyrophosphokinase, vitamin B1 binding domain
IOLKFBCL_01143	3.43e-111	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
IOLKFBCL_01144	1.4e-36	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L35
IOLKFBCL_01145	7.76e-81	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
IOLKFBCL_01146	2.09e-215	xerD	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	recombinase XerD
IOLKFBCL_01147	8.08e-193	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	CobQ CobB MinD ParA nucleotide binding domain protein
IOLKFBCL_01148	2.2e-199	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IOLKFBCL_01149	2.14e-148	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IOLKFBCL_01150	7.49e-197	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX hydrolase
IOLKFBCL_01151	0.0	nadA	2.5.1.72	-	H	ko:K03517	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
IOLKFBCL_01152	0.0	nadB	1.4.3.16, 2.4.2.19	-	H	ko:K00278,ko:K00767	ko00250,ko00760,ko01100,map00250,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of L-aspartate to iminoaspartate
IOLKFBCL_01153	1.07e-207	nadC	2.4.2.19	-	H	ko:K00767	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Quinolinate phosphoribosyl transferase, N-terminal domain
IOLKFBCL_01154	3.1e-271	iscS1	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class-V
IOLKFBCL_01155	0.0	typA	-	-	T	ko:K06207	-	ko00000	Elongation factor G C-terminus
IOLKFBCL_01157	6.31e-46	-	-	-	L	-	-	-	PFAM Integrase catalytic
IOLKFBCL_01158	2.17e-97	-	-	-	-	-	-	-	-
IOLKFBCL_01159	1.52e-243	pheA	4.2.1.51, 5.4.99.5	-	E	ko:K04518,ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Prephenate dehydratase
IOLKFBCL_01160	2.47e-240	tyrA	1.3.1.12	-	E	ko:K00210,ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Prephenate dehydrogenase
IOLKFBCL_01161	3.75e-57	-	-	-	-	-	-	-	-
IOLKFBCL_01162	6.16e-238	xerC	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family. XerC subfamily
IOLKFBCL_01163	0.0	dppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, family 5
IOLKFBCL_01164	1.89e-202	dppB	-	-	EP	ko:K02033,ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOLKFBCL_01165	1.82e-229	dppC	-	-	EP	ko:K02034,ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	N-terminal TM domain of oligopeptide transport permease C
IOLKFBCL_01166	0.0	-	-	-	EP	ko:K02031,ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Oligopeptide/dipeptide transporter, C-terminal region
IOLKFBCL_01167	1.08e-215	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease/Exonuclease/phosphatase family
IOLKFBCL_01168	2.45e-186	-	-	-	S	-	-	-	Protein of unknown function (DUF3710)
IOLKFBCL_01169	2.19e-156	-	-	-	S	-	-	-	Protein of unknown function (DUF3159)
IOLKFBCL_01170	4.96e-308	rumA	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IOLKFBCL_01171	2.54e-148	-	-	-	-	-	-	-	-
IOLKFBCL_01172	0.0	ctpE	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
IOLKFBCL_01173	0.0	acnA	4.2.1.3	-	C	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
IOLKFBCL_01174	4.99e-76	-	-	-	L	-	-	-	RelB antitoxin
IOLKFBCL_01175	1.8e-110	-	-	-	S	-	-	-	PIN domain
IOLKFBCL_01176	0.0	-	-	-	S	-	-	-	Protein of unknown function DUF262
IOLKFBCL_01177	1.11e-152	-	-	-	E	-	-	-	Psort location Cytoplasmic, score 8.87
IOLKFBCL_01178	2.62e-189	-	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
IOLKFBCL_01179	2.77e-226	-	-	-	EG	-	-	-	EamA-like transporter family
IOLKFBCL_01180	2.32e-174	ywaC	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	Region found in RelA / SpoT proteins
IOLKFBCL_01181	0.0	miaB	2.8.4.3	-	H	ko:K06168	-	ko00000,ko01000,ko03016	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
IOLKFBCL_01182	3.56e-233	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
IOLKFBCL_01183	7.92e-175	fic	-	-	D	ko:K04095	-	ko00000,ko03036	Fic/DOC family
IOLKFBCL_01184	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	FtsK SpoIIIE family protein
IOLKFBCL_01185	4.82e-151	pgsA	2.7.8.41, 2.7.8.5	-	I	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IOLKFBCL_01186	2.13e-118	cinA	3.5.1.42	-	S	ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
IOLKFBCL_01187	1.06e-106	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
IOLKFBCL_01188	4.64e-52	-	-	-	S	-	-	-	Protein of unknown function (DUF3046)
IOLKFBCL_01189	2.91e-260	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
IOLKFBCL_01190	3.06e-130	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Modulates RecA activity
IOLKFBCL_01191	1.24e-154	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IOLKFBCL_01192	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
IOLKFBCL_01193	3.93e-82	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
IOLKFBCL_01194	4.3e-219	trpD	2.4.2.18	-	F	ko:K00766	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IOLKFBCL_01195	9.83e-110	-	-	-	-	-	-	-	-
IOLKFBCL_01196	1.56e-166	plsC2	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Phosphate acyltransferases
IOLKFBCL_01197	0.0	pknL	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	PASTA
IOLKFBCL_01198	4.54e-243	idsA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13787	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
IOLKFBCL_01199	1.1e-157	-	-	-	-	-	-	-	-
IOLKFBCL_01200	1.03e-243	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
IOLKFBCL_01201	0.0	gyrB2	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	DNA topoisomerase (ATP-hydrolyzing)
IOLKFBCL_01202	1.29e-264	-	-	-	G	-	-	-	Major Facilitator Superfamily
IOLKFBCL_01203	2.92e-219	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IOLKFBCL_01204	0.0	lhr	-	-	L	ko:K03724	-	ko00000,ko01000,ko03400	DEAD DEAH box helicase
IOLKFBCL_01205	1.05e-160	-	-	-	KT	-	-	-	RESPONSE REGULATOR receiver
IOLKFBCL_01206	0.0	gyrA2	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	DNA topoisomerase (ATP-hydrolyzing)
IOLKFBCL_01207	3.02e-298	-	-	-	S	-	-	-	Type I phosphodiesterase / nucleotide pyrophosphatase
IOLKFBCL_01208	1.44e-236	-	-	-	S	-	-	-	Protein of unknown function (DUF3071)
IOLKFBCL_01209	1.42e-62	-	-	-	S	-	-	-	Domain of unknown function (DUF4193)
IOLKFBCL_01210	1.62e-106	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
IOLKFBCL_01211	0.0	relA	2.7.6.5, 3.1.7.2	-	KT	ko:K00951,ko:K01139	ko00230,map00230	ko00000,ko00001,ko01000,ko03009	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IOLKFBCL_01212	5.43e-122	ppiA	5.2.1.8	-	G	ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	ko00000,ko00001,ko01000,ko03110,ko04147	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IOLKFBCL_01213	1.53e-97	-	-	-	-	-	-	-	-
IOLKFBCL_01215	5.6e-308	-	-	-	S	-	-	-	HipA-like C-terminal domain
IOLKFBCL_01216	6.19e-145	-	-	-	S	-	-	-	Fic/DOC family
IOLKFBCL_01217	4.94e-103	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
IOLKFBCL_01218	1.59e-137	-	-	-	S	-	-	-	KR domain
IOLKFBCL_01219	2.19e-196	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
IOLKFBCL_01220	6.21e-47	-	-	-	S	-	-	-	Fic/DOC family
IOLKFBCL_01222	5.35e-305	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
IOLKFBCL_01223	3.91e-46	-	-	-	D	-	-	-	Filamentation induced by cAMP protein fic
IOLKFBCL_01224	1.44e-259	-	-	-	L	-	-	-	Transposase, Mutator family
IOLKFBCL_01225	3.96e-15	-	2.1.1.72	-	L	ko:K07316	-	ko00000,ko01000,ko02048	Belongs to the N(4) N(6)-methyltransferase family
IOLKFBCL_01227	1.53e-35	-	-	-	-	-	-	-	-
IOLKFBCL_01228	8.73e-186	fic	-	-	D	ko:K04095	-	ko00000,ko03036	Fic/DOC family
IOLKFBCL_01229	0.0	intA	-	-	L	-	-	-	Phage integrase family
IOLKFBCL_01230	4.72e-45	-	-	-	P	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOLKFBCL_01231	3.62e-249	-	-	-	S	-	-	-	Short C-terminal domain
IOLKFBCL_01232	1.43e-51	-	-	-	-	-	-	-	-
IOLKFBCL_01233	2.72e-285	-	-	-	-	-	-	-	-
IOLKFBCL_01234	2.87e-101	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
IOLKFBCL_01235	0.0	-	-	-	KLT	-	-	-	Protein tyrosine kinase
IOLKFBCL_01236	0.0	-	-	-	EGP	ko:K08217	-	br01600,ko00000,ko01504,ko02000	Transmembrane secretion effector
IOLKFBCL_01237	0.0	-	-	-	U	-	-	-	Drug resistance MFS transporter, drug H antiporter-2 family
IOLKFBCL_01238	2.7e-17	-	-	-	-	-	-	-	-
IOLKFBCL_01239	2.35e-151	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
IOLKFBCL_01240	1.04e-273	-	-	-	G	-	-	-	Transmembrane secretion effector
IOLKFBCL_01241	2.19e-309	-	-	-	S	-	-	-	HipA-like C-terminal domain
IOLKFBCL_01242	5.09e-51	-	-	-	L	ko:K07473	-	ko00000,ko02048	RelB antitoxin
IOLKFBCL_01243	1.92e-67	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	PemK-like, MazF-like toxin of type II toxin-antitoxin system
IOLKFBCL_01244	2.26e-108	-	-	-	S	-	-	-	Cupin 2, conserved barrel domain protein
IOLKFBCL_01245	6.44e-205	-	-	-	J	-	-	-	Methyltransferase domain
IOLKFBCL_01246	7.81e-79	yccF	-	-	S	-	-	-	Inner membrane component domain
IOLKFBCL_01247	3.18e-299	-	-	-	K	-	-	-	Fic/DOC family
IOLKFBCL_01248	2.25e-31	-	-	-	L	-	-	-	Transposase, Mutator family
IOLKFBCL_01249	0.0	-	-	-	L	-	-	-	ABC transporter
IOLKFBCL_01250	4.79e-307	-	-	-	V	-	-	-	MatE
IOLKFBCL_01252	2.31e-36	-	-	-	S	ko:K02890,ko:K07343	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	rRNA binding
IOLKFBCL_01253	2.63e-207	tetD	-	-	K	ko:K13653	-	ko00000,ko03000	Arac family
IOLKFBCL_01254	4.15e-258	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
IOLKFBCL_01255	6.51e-181	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IOLKFBCL_01256	0.0	pip	3.4.11.5	-	S	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	alpha/beta hydrolase fold
IOLKFBCL_01258	0.0	-	-	-	T	-	-	-	Histidine kinase
IOLKFBCL_01259	5.96e-182	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
IOLKFBCL_01260	0.0	-	-	-	MV	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
IOLKFBCL_01261	8.85e-184	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IOLKFBCL_01262	9.49e-317	-	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Aminotransferase class-V
IOLKFBCL_01263	3.75e-209	pdxY	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
IOLKFBCL_01264	3.62e-121	yraN	-	-	L	ko:K07460	-	ko00000	Belongs to the UPF0102 family
IOLKFBCL_01265	0.0	comM	-	-	O	ko:K07391	-	ko00000	Magnesium chelatase, subunit ChlI C-terminal
IOLKFBCL_01266	0.0	dprA	-	-	LU	ko:K04096	-	ko00000	DNA recombination-mediator protein A
IOLKFBCL_01267	0.0	sdhA	1.3.5.1, 1.3.5.4, 1.4.3.16	-	C	ko:K00239,ko:K00278	ko00020,ko00190,ko00250,ko00650,ko00720,ko00760,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00250,map00650,map00720,map00760,map01100,map01110,map01120,map01130,map01200,map05134	ko00000,ko00001,ko00002,ko01000	Succinate dehydrogenase flavoprotein subunit
IOLKFBCL_01268	7.19e-234	sdhB	1.3.5.1, 1.3.5.4	-	C	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	4Fe-4S dicluster domain
IOLKFBCL_01269	2.45e-141	safC	-	-	S	-	-	-	O-methyltransferase
IOLKFBCL_01270	9.06e-208	fmt2	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
IOLKFBCL_01271	1.54e-306	nhaA	-	-	P	ko:K03313	-	ko00000,ko02000	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
IOLKFBCL_01274	3.4e-311	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
IOLKFBCL_01275	1.81e-158	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
IOLKFBCL_01276	4.2e-151	clpP1	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
IOLKFBCL_01277	2.82e-78	-	-	-	-	-	-	-	-
IOLKFBCL_01278	3e-299	-	-	-	P	ko:K03281	-	ko00000	Voltage gated chloride channel
IOLKFBCL_01279	4.94e-304	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
IOLKFBCL_01280	9.6e-317	rnd	3.1.13.5	-	J	ko:K03684	-	ko00000,ko01000,ko03016	3'-5' exonuclease
IOLKFBCL_01281	5.5e-154	-	-	-	S	-	-	-	Protein of unknown function (DUF3000)
IOLKFBCL_01282	1.49e-221	pflA	1.97.1.4	-	C	ko:K04069	-	ko00000,ko01000	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IOLKFBCL_01283	0.0	pflB	2.3.1.54	-	C	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	Pyruvate formate lyase-like
IOLKFBCL_01284	9.66e-46	-	-	-	-	-	-	-	-
IOLKFBCL_01285	0.0	nadE	6.3.5.1	-	H	ko:K01950	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IOLKFBCL_01286	1.64e-284	-	-	-	S	-	-	-	Peptidase dimerisation domain
IOLKFBCL_01287	1.12e-145	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOLKFBCL_01288	1.5e-276	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IOLKFBCL_01289	1.22e-223	-	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	NLPA lipoprotein
IOLKFBCL_01290	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase
IOLKFBCL_01291	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
IOLKFBCL_01292	0.0	yrhL	-	-	I	-	-	-	Psort location CytoplasmicMembrane, score 9.99
IOLKFBCL_01293	1.59e-244	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IOLKFBCL_01295	0.0	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
IOLKFBCL_01296	5.2e-82	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
IOLKFBCL_01297	2.28e-156	gpmB	3.1.3.85, 5.4.2.11	-	G	ko:K01834,ko:K22306	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Phosphoglycerate mutase family
IOLKFBCL_01300	0.0	pta	2.3.1.8	-	C	ko:K13788	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	phosphate acetyltransferase
IOLKFBCL_01301	2.87e-289	ackA	2.7.2.1	-	H	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IOLKFBCL_01302	6.91e-315	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
IOLKFBCL_01303	1.58e-249	-	-	-	-	-	-	-	-
IOLKFBCL_01306	1.21e-18	-	-	-	K	-	-	-	Putative zinc ribbon domain
IOLKFBCL_01307	0.0	glgX	3.2.1.68	CBM48,GH13	G	ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 13 family
IOLKFBCL_01308	2.32e-161	-	-	-	L	-	-	-	NUDIX domain
IOLKFBCL_01309	3.98e-228	-	-	-	L	-	-	-	NIF3 (NGG1p interacting factor 3)
IOLKFBCL_01310	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IOLKFBCL_01311	3.04e-164	pdtaR	-	-	T	ko:K22010	-	ko00000,ko00002,ko02022	Response regulator receiver domain protein
IOLKFBCL_01313	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Pyruvate kinase
IOLKFBCL_01314	1.09e-227	terC	-	-	P	ko:K05794	-	ko00000	Integral membrane protein, TerC family
IOLKFBCL_01315	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
IOLKFBCL_01316	9.26e-69	-	-	-	T	-	-	-	Histidine kinase
IOLKFBCL_01317	1.06e-80	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
IOLKFBCL_01318	4.91e-177	XK27_10205	-	-	-	ko:K02004	-	ko00000,ko00002,ko02000	-
IOLKFBCL_01319	4.34e-95	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
IOLKFBCL_01320	1.79e-93	coaE	2.7.1.24	-	H	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
IOLKFBCL_01321	0.0	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
IOLKFBCL_01322	9.81e-201	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IOLKFBCL_01323	2.9e-258	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Zinc-uptake complex component A periplasmic
IOLKFBCL_01324	5.11e-210	-	-	-	P	ko:K02074	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
IOLKFBCL_01325	6.66e-176	znuB	-	-	U	ko:K02075	-	ko00000,ko00002,ko02000	ABC 3 transport family
IOLKFBCL_01326	9.43e-116	ispF	2.7.7.60, 4.6.1.12	-	H	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
IOLKFBCL_01327	1.85e-131	carD	-	-	K	ko:K07736	-	ko00000,ko03000	CarD-like/TRCF domain
IOLKFBCL_01328	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
IOLKFBCL_01329	8.63e-165	cseB	-	-	T	-	-	-	Response regulator receiver domain protein
IOLKFBCL_01330	2.36e-248	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
IOLKFBCL_01331	2.22e-85	umuD	-	-	KT	ko:K03503	-	ko00000,ko01000,ko01002,ko03400	Peptidase S24-like
IOLKFBCL_01332	2.41e-71	pyrE_1	-	-	S	-	-	-	Phosphoribosyl transferase domain
IOLKFBCL_01333	1.29e-193	-	-	-	T	-	-	-	Eukaryotic phosphomannomutase
IOLKFBCL_01334	3.82e-95	-	-	-	S	-	-	-	Zincin-like metallopeptidase
IOLKFBCL_01335	0.0	-	-	-	-	-	-	-	-
IOLKFBCL_01336	0.0	-	-	-	S	-	-	-	Glycosyl transferase, family 2
IOLKFBCL_01337	7.16e-75	whiB2	-	-	K	ko:K18955	-	ko00000,ko03000	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
IOLKFBCL_01338	7.26e-207	lytR2	-	-	K	-	-	-	Cell envelope-related transcriptional attenuator domain
IOLKFBCL_01339	0.0	-	-	-	D	ko:K03466	-	ko00000,ko03036	FtsK/SpoIIIE family
IOLKFBCL_01340	3.32e-61	whiB	-	-	K	ko:K18955	-	ko00000,ko03000	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
IOLKFBCL_01341	0.0	pdtaS	2.7.13.3	-	T	ko:K00936	-	ko00000,ko00002,ko01000,ko01001,ko02022	ATPase histidine kinase DNA gyrase B HSP90 domain protein
IOLKFBCL_01342	7.85e-175	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	Haemolysin-III related
IOLKFBCL_01343	7.1e-106	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
IOLKFBCL_01344	5.53e-96	fkbP	5.2.1.8	-	G	ko:K01802	-	ko00000,ko01000	Peptidyl-prolyl cis-trans
IOLKFBCL_01345	0.0	sdaA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase alpha chain
IOLKFBCL_01346	1.35e-120	-	-	-	-	-	-	-	-
IOLKFBCL_01348	9.72e-229	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	Ppx/GppA phosphatase family
IOLKFBCL_01349	1.61e-132	-	-	-	S	ko:K09009	-	ko00000	Protein of unknown function (DUF501)
IOLKFBCL_01350	9.56e-103	-	-	-	D	-	-	-	Septum formation initiator
IOLKFBCL_01351	3.54e-313	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
IOLKFBCL_01352	2.62e-220	-	-	-	C	-	-	-	Aldo/keto reductase family
IOLKFBCL_01353	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IOLKFBCL_01354	4.23e-147	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
IOLKFBCL_01355	2.11e-93	-	-	-	S	-	-	-	PIN domain
IOLKFBCL_01356	3.89e-62	-	-	-	S	-	-	-	RelB antitoxin
IOLKFBCL_01357	3.22e-114	-	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
IOLKFBCL_01358	0.0	-	-	-	S	ko:K09118	-	ko00000	Uncharacterised protein family (UPF0182)
IOLKFBCL_01359	7.51e-265	-	3.2.1.52	-	G	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	ko00000,ko00001,ko00002,ko01000	Glycosyl hydrolase family 3 N-terminal domain protein
IOLKFBCL_01360	5.62e-176	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
IOLKFBCL_01361	6.47e-130	-	-	-	-	-	-	-	-
IOLKFBCL_01362	7.42e-294	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
IOLKFBCL_01363	0.0	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IOLKFBCL_01364	0.0	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase N terminus
IOLKFBCL_01365	1.36e-250	-	-	-	S	-	-	-	Protein of unknown function (DUF1648)
IOLKFBCL_01366	2e-98	-	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
IOLKFBCL_01367	8.18e-293	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative ATP-dependent DNA helicase recG C-terminal
IOLKFBCL_01368	1.24e-52	pacL2	3.6.3.8	-	P	ko:K01537,ko:K12955	-	ko00000,ko01000	ATPase, P-type transporting, HAD superfamily, subfamily IC
IOLKFBCL_01369	2.8e-91	-	-	-	S	-	-	-	ABC-2 family transporter protein
IOLKFBCL_01370	1.94e-155	-	-	-	S	-	-	-	ABC-2 family transporter protein
IOLKFBCL_01371	1.32e-222	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
IOLKFBCL_01372	3.46e-78	-	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
IOLKFBCL_01373	1.27e-75	-	-	-	EGP	-	-	-	Major facilitator Superfamily
IOLKFBCL_01375	1.51e-148	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
IOLKFBCL_01376	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
IOLKFBCL_01377	8.22e-246	nadK	2.7.1.23	-	H	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IOLKFBCL_01378	1.12e-125	-	-	-	-	-	-	-	-
IOLKFBCL_01379	2.37e-175	tlyA	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
IOLKFBCL_01381	1.22e-249	-	-	-	G	-	-	-	Haloacid dehalogenase-like hydrolase
IOLKFBCL_01382	6.78e-227	-	-	-	L	-	-	-	Tetratricopeptide repeat
IOLKFBCL_01383	0.0	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IOLKFBCL_01384	1.67e-174	-	-	-	S	-	-	-	Putative ABC-transporter type IV
IOLKFBCL_01385	1.24e-126	-	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
IOLKFBCL_01386	1.76e-73	-	-	-	P	-	-	-	Rhodanese Homology Domain
IOLKFBCL_01387	1.19e-190	thiF	2.7.7.73, 2.7.7.80, 2.8.1.11	-	H	ko:K03148,ko:K21147	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	ThiF family
IOLKFBCL_01388	1.19e-200	thiG	2.8.1.10	-	H	ko:K03149	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
IOLKFBCL_01389	5.04e-39	thiS	-	-	H	ko:K03154	ko04122,map04122	ko00000,ko00001	ThiS family
IOLKFBCL_01390	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
IOLKFBCL_01391	4.9e-303	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
IOLKFBCL_01392	4.34e-110	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
IOLKFBCL_01393	7.19e-234	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IOLKFBCL_01394	9.37e-313	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class-III
IOLKFBCL_01395	3.68e-212	argB	2.7.2.8	-	E	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetylglutamate kinase family. ArgB subfamily
IOLKFBCL_01396	7.94e-271	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
IOLKFBCL_01397	1.02e-257	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
IOLKFBCL_01398	3.07e-143	-	-	-	-	-	-	-	-
IOLKFBCL_01399	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Phenylalanyl-tRNA synthetase beta
IOLKFBCL_01400	1.83e-258	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
IOLKFBCL_01401	9.21e-211	tsnR	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IOLKFBCL_01402	9.39e-191	ykoC	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
IOLKFBCL_01403	0.0	ykoD	-	-	P	ko:K16785,ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
IOLKFBCL_01404	7.57e-141	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
IOLKFBCL_01405	0.0	argE	-	-	E	-	-	-	Peptidase dimerisation domain
IOLKFBCL_01406	5.45e-138	-	-	-	S	-	-	-	Protein of unknown function (DUF3043)
IOLKFBCL_01407	0.0	lpdA	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IOLKFBCL_01408	7.35e-176	-	-	-	S	-	-	-	Domain of unknown function (DUF4191)
IOLKFBCL_01409	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
IOLKFBCL_01410	4.08e-107	-	3.2.1.23, 3.2.1.31	-	G	ko:K01190,ko:K01195	ko00040,ko00052,ko00511,ko00531,ko00600,ko00860,ko00944,ko00983,ko01100,ko01110,ko04142,map00040,map00052,map00511,map00531,map00600,map00860,map00944,map00983,map01100,map01110,map04142	ko00000,ko00001,ko00002,ko01000	Glycosyl hydrolases family 2, TIM barrel domain
IOLKFBCL_01411	2.57e-234	-	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
IOLKFBCL_01412	9.16e-99	-	2.3.1.18, 2.3.1.79	-	S	ko:K00633,ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
IOLKFBCL_01413	3.36e-108	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
IOLKFBCL_01415	1.7e-150	-	-	-	L	ko:K07457	-	ko00000	endonuclease III
IOLKFBCL_01416	8.96e-308	-	-	-	V	-	-	-	MatE
IOLKFBCL_01417	0.0	uvrA3	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
IOLKFBCL_01418	0.0	-	-	-	H	-	-	-	Protein of unknown function (DUF4012)
IOLKFBCL_01419	2.79e-38	-	-	-	S	-	-	-	Domain of unknown function (DUF4913)
IOLKFBCL_01420	1.04e-92	istB	-	-	L	-	-	-	IstB-like ATP binding protein
IOLKFBCL_01421	1.73e-60	-	-	-	L	-	-	-	PFAM Integrase catalytic
IOLKFBCL_01422	5.34e-76	-	-	-	L	ko:K07493	-	ko00000	PFAM Transposase, Mutator family
IOLKFBCL_01424	3.58e-198	-	-	-	V	-	-	-	ATPases associated with a variety of cellular activities
IOLKFBCL_01425	6.6e-241	-	-	-	V	-	-	-	ABC transporter
IOLKFBCL_01426	1.44e-56	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
IOLKFBCL_01427	0.0	pnp	2.7.7.8	-	J	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
IOLKFBCL_01428	5.25e-313	-	-	-	S	ko:K06901	-	ko00000,ko02000	Permease family
IOLKFBCL_01429	1.65e-180	-	-	-	S	-	-	-	alpha beta
IOLKFBCL_01430	2.41e-113	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
IOLKFBCL_01431	6.07e-64	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
IOLKFBCL_01432	6.37e-249	-	-	-	T	-	-	-	Forkhead associated domain
IOLKFBCL_01433	0.0	-	-	-	L	-	-	-	Superfamily I DNA and RNA helicases and helicase subunits
IOLKFBCL_01434	2.09e-41	-	-	-	-	-	-	-	-
IOLKFBCL_01435	5.03e-121	-	-	-	NO	-	-	-	SAF
IOLKFBCL_01436	2.17e-43	-	-	-	S	-	-	-	Putative regulatory protein
IOLKFBCL_01437	4.56e-166	ygfA	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	5-formyltetrahydrofolate cyclo-ligase family
IOLKFBCL_01438	2.42e-166	rimJ	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
IOLKFBCL_01439	6.02e-277	-	-	-	-	-	-	-	-
IOLKFBCL_01440	6.02e-64	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
IOLKFBCL_01441	2.94e-51	megL	4.4.1.11	-	E	ko:K01761	ko00270,ko00450,map00270,map00450	ko00000,ko00001,ko01000	Cys/Met metabolism PLP-dependent enzyme
IOLKFBCL_01445	1.03e-34	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L33
IOLKFBCL_01446	1.17e-287	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
IOLKFBCL_01447	0.0	-	-	-	E	ko:K03294	-	ko00000	aromatic amino acid transport protein AroP K03293
IOLKFBCL_01448	1.57e-79	fdxA	-	-	C	ko:K05524	-	ko00000	4Fe-4S binding domain
IOLKFBCL_01449	4.38e-285	dapC	-	-	E	-	-	-	Aminotransferase class I and II
IOLKFBCL_01450	3.34e-298	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IOLKFBCL_01453	3.58e-238	pdxB	-	-	EH	-	-	-	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IOLKFBCL_01454	5.2e-139	yigZ	-	-	S	-	-	-	Uncharacterized protein family UPF0029
IOLKFBCL_01455	3.49e-147	-	-	-	-	-	-	-	-
IOLKFBCL_01456	0.0	malQ	2.4.1.25	GH77	G	ko:K00705	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	4-alpha-glucanotransferase
IOLKFBCL_01457	3.75e-103	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IOLKFBCL_01458	9.6e-106	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
IOLKFBCL_01459	0.0	glgX	3.2.1.196, 3.2.1.68	CBM48,GH13	G	ko:K01214,ko:K02438	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 13 family
IOLKFBCL_01460	1.53e-221	-	1.1.1.1, 1.1.1.287, 1.6.5.5	-	C	ko:K00001,ko:K00344,ko:K17818	ko00010,ko00040,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00040,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Zinc-binding dehydrogenase
IOLKFBCL_01461	1.1e-283	csbX	-	-	EGP	-	-	-	Major Facilitator Superfamily
IOLKFBCL_01462	9.69e-87	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IOLKFBCL_01463	1.9e-275	csbX	-	-	EGP	-	-	-	Major Facilitator Superfamily
IOLKFBCL_01464	1.31e-244	-	1.1.1.9	-	C	ko:K05351	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Zinc-binding dehydrogenase
IOLKFBCL_01465	3.56e-174	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
IOLKFBCL_01467	6.5e-280	-	-	-	GK	-	-	-	transcriptional repressor of nag (N-acetylglucosamine) operon K02565
IOLKFBCL_01468	0.0	adhE	1.1.1.1, 1.2.1.10, 1.2.1.81	-	C	ko:K04072,ko:K15515	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
IOLKFBCL_01469	1.4e-190	-	-	-	S	-	-	-	YwiC-like protein
IOLKFBCL_01470	9.35e-68	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
IOLKFBCL_01471	1.57e-149	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IOLKFBCL_01472	1.97e-150	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
IOLKFBCL_01473	8.86e-62	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
IOLKFBCL_01474	1.34e-195	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
IOLKFBCL_01475	1.4e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
IOLKFBCL_01476	1.55e-74	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
IOLKFBCL_01477	1.32e-161	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
IOLKFBCL_01478	3.85e-98	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
IOLKFBCL_01479	1.97e-49	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
IOLKFBCL_01480	1.11e-54	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
IOLKFBCL_01481	2.55e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
IOLKFBCL_01482	1.09e-68	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
IOLKFBCL_01483	2.77e-134	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
IOLKFBCL_01484	7.06e-40	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IOLKFBCL_01485	3.17e-90	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
IOLKFBCL_01486	7.72e-122	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
IOLKFBCL_01487	3.43e-75	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
IOLKFBCL_01488	2.82e-128	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
IOLKFBCL_01489	4.64e-36	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30p/L7e
IOLKFBCL_01490	1.52e-98	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
IOLKFBCL_01491	1.87e-316	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
IOLKFBCL_01492	7.36e-128	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
IOLKFBCL_01493	6.91e-45	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
IOLKFBCL_01494	1.47e-20	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
IOLKFBCL_01495	1.16e-81	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
IOLKFBCL_01496	7.34e-86	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
IOLKFBCL_01497	4.01e-236	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IOLKFBCL_01498	1.83e-86	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
IOLKFBCL_01499	4.75e-214	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
IOLKFBCL_01500	0.0	gcs2	-	-	S	ko:K06048	-	ko00000,ko01000	A circularly permuted ATPgrasp
IOLKFBCL_01501	2.82e-192	-	-	-	E	-	-	-	Transglutaminase/protease-like homologues
IOLKFBCL_01502	6e-275	-	-	-	S	ko:K07133	-	ko00000	Psort location Cytoplasmic, score
IOLKFBCL_01504	5.07e-18	-	-	-	L	-	-	-	Integrase core domain
IOLKFBCL_01505	6.64e-205	-	-	-	P	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOLKFBCL_01506	2.54e-220	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOLKFBCL_01507	1.37e-308	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
IOLKFBCL_01508	3.09e-159	-	-	-	-	-	-	-	-
IOLKFBCL_01509	4.19e-241	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
IOLKFBCL_01510	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
IOLKFBCL_01511	1.05e-95	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IOLKFBCL_01512	2.64e-267	truB	5.4.99.25	-	J	ko:K03177	-	ko00000,ko01000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IOLKFBCL_01513	1.68e-277	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	riboflavin kinase
IOLKFBCL_01514	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
IOLKFBCL_01515	5.79e-130	-	-	-	-	-	-	-	-
IOLKFBCL_01516	5.05e-07	-	-	-	S	-	-	-	Mitochondrial domain of unknown function (DUF1713)
IOLKFBCL_01517	1.44e-159	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
IOLKFBCL_01518	1.38e-189	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IOLKFBCL_01520	0.0	merA	1.16.1.1	-	C	ko:K00520,ko:K21739	-	ko00000,ko01000	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IOLKFBCL_01521	1.06e-89	-	-	-	K	-	-	-	Transcriptional regulator
IOLKFBCL_01522	7.16e-118	-	-	-	S	-	-	-	Protein conserved in bacteria
IOLKFBCL_01523	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II
IOLKFBCL_01524	0.0	ptsG	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	pts system, glucose-specific IIABC component
IOLKFBCL_01525	6.92e-204	arbG	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
IOLKFBCL_01526	4.92e-266	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
IOLKFBCL_01527	9.91e-302	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
IOLKFBCL_01529	0.0	gnpA	2.4.1.211	-	S	ko:K15533	-	ko00000,ko01000	Lacto-N-biose phosphorylase C-terminal domain
IOLKFBCL_01530	2.22e-238	-	2.7.1.162	-	S	ko:K13059	-	ko00000,ko01000	Phosphotransferase enzyme family
IOLKFBCL_01531	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
IOLKFBCL_01532	9.84e-237	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
IOLKFBCL_01533	1.17e-143	tcsR3	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
IOLKFBCL_01534	1.2e-287	tcsS3	-	-	KT	-	-	-	PspC domain
IOLKFBCL_01535	4.44e-231	pspC	-	-	KT	-	-	-	PspC domain
IOLKFBCL_01536	3.53e-101	-	-	-	-	-	-	-	-
IOLKFBCL_01537	0.0	-	-	-	S	ko:K06889	-	ko00000	alpha beta
IOLKFBCL_01538	1.34e-144	-	-	-	S	-	-	-	Protein of unknown function (DUF4125)
IOLKFBCL_01539	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF4037)
IOLKFBCL_01540	0.0	-	-	-	I	-	-	-	PAP2 superfamily
IOLKFBCL_01541	2.71e-262	-	-	-	EGP	ko:K08156,ko:K19577	-	ko00000,ko02000	Major Facilitator Superfamily
IOLKFBCL_01543	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
IOLKFBCL_01544	6.97e-216	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the MenA family. Type 1 subfamily
IOLKFBCL_01545	3.69e-178	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
IOLKFBCL_01546	2.46e-147	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
IOLKFBCL_01547	6.48e-254	senX3	2.7.13.3	-	T	ko:K07768	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	ATPase histidine kinase DNA gyrase B HSP90 domain protein
IOLKFBCL_01548	1.97e-50	-	-	-	-	-	-	-	-
IOLKFBCL_01549	6.07e-274	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
IOLKFBCL_01550	1.85e-214	-	-	-	S	-	-	-	CHAP domain
IOLKFBCL_01551	3.42e-118	-	-	-	M	-	-	-	NlpC/P60 family
IOLKFBCL_01552	1.81e-137	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC/P60 family
IOLKFBCL_01553	3.06e-238	-	-	-	T	-	-	-	Universal stress protein family
IOLKFBCL_01554	9.14e-96	-	-	-	O	-	-	-	OsmC-like protein
IOLKFBCL_01555	8.29e-222	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
IOLKFBCL_01557	6.93e-161	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	dihydrofolate reductase
IOLKFBCL_01558	2.08e-127	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	low molecular weight
IOLKFBCL_01559	1.98e-142	vex	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IOLKFBCL_01560	6.2e-267	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	Efflux ABC transporter, permease protein
IOLKFBCL_01561	7.23e-288	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
IOLKFBCL_01562	2.77e-290	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
IOLKFBCL_01563	1.34e-61	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
IOLKFBCL_01564	0.0	ilvD	4.2.1.9	-	H	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the IlvD Edd family
IOLKFBCL_01565	1.14e-229	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
IOLKFBCL_01566	1.69e-168	-	3.8.1.2	-	S	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
IOLKFBCL_01567	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IOLKFBCL_01568	7.09e-164	serB	3.1.3.3	-	E	ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01009	haloacid dehalogenase-like hydrolase
IOLKFBCL_01569	9.02e-163	-	-	-	S	-	-	-	SNARE associated Golgi protein
IOLKFBCL_01570	0.0	arc	-	-	O	ko:K13527	ko03050,map03050	ko00000,ko00001,ko00002,ko03051	AAA ATPase forming ring-shaped complexes
IOLKFBCL_01571	0.0	dop	3.5.1.119	-	S	ko:K20814	-	ko00000,ko01000,ko03051	Pup-ligase protein
IOLKFBCL_01572	1.94e-215	-	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Inositol monophosphatase family
IOLKFBCL_01573	5.61e-24	pup	-	-	S	ko:K13570	-	ko00000,ko04121	Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation
IOLKFBCL_01574	0.0	pafA	6.3.1.19	-	O	ko:K13571	-	ko00000,ko00002,ko01000,ko03051	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
IOLKFBCL_01575	0.0	bga1	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
IOLKFBCL_01576	0.0	-	-	-	S	-	-	-	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
IOLKFBCL_01578	9.03e-200	-	-	-	S	-	-	-	AAA ATPase domain
IOLKFBCL_01579	1.04e-24	-	-	-	L	-	-	-	Transposase
IOLKFBCL_01580	3.74e-300	-	-	-	K	-	-	-	Putative DNA-binding domain
IOLKFBCL_01581	8.3e-78	-	-	-	-	-	-	-	-
IOLKFBCL_01583	2.15e-291	rfbP	-	-	M	-	-	-	Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
IOLKFBCL_01584	2.45e-139	etp	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Low molecular weight phosphatase family
IOLKFBCL_01585	5.16e-140	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.99
IOLKFBCL_01586	4.79e-210	-	-	GT4	M	ko:K12996	-	ko00000,ko01000,ko01003,ko01005	Domain of unknown function (DUF1972)
IOLKFBCL_01587	1.36e-214	-	-	-	M	-	-	-	Glycosyl transferase 4-like domain
IOLKFBCL_01588	1.14e-63	-	-	-	S	-	-	-	Hexapeptide repeat of succinyl-transferase
IOLKFBCL_01589	8.53e-36	-	-	-	M	-	-	-	Glycosyltransferase, group 2 family protein
IOLKFBCL_01590	5.33e-10	-	-	-	M	-	-	-	O-antigen ligase
IOLKFBCL_01591	3.78e-172	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.99
IOLKFBCL_01592	6.27e-147	-	-	-	C	-	-	-	Polysaccharide pyruvyl transferase
IOLKFBCL_01593	6.22e-56	-	-	-	S	-	-	-	Core-2/I-Branching enzyme
IOLKFBCL_01595	5.01e-255	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
IOLKFBCL_01596	2.51e-25	-	-	-	-	-	-	-	-
IOLKFBCL_01597	0.0	rfbD	1.1.1.133, 5.1.3.13	-	M	ko:K00067,ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
IOLKFBCL_01598	5.16e-217	rfbA	2.7.7.24	-	H	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
IOLKFBCL_01600	4.71e-27	-	-	-	S	-	-	-	enterobacterial common antigen metabolic process
IOLKFBCL_01601	4.67e-315	-	-	-	L	-	-	-	HTH-like domain
IOLKFBCL_01602	7.38e-44	-	-	-	L	ko:K07483	-	ko00000	Transposase
IOLKFBCL_01603	6.24e-184	tnp3521a2	-	-	L	-	-	-	Integrase core domain
IOLKFBCL_01604	1.2e-60	-	-	-	S	-	-	-	SIR2-like domain
IOLKFBCL_01605	0.0	-	-	-	S	ko:K06915	-	ko00000	AAA-like domain
IOLKFBCL_01606	2.27e-64	-	-	-	L	-	-	-	Helix-turn-helix domain
IOLKFBCL_01607	2.07e-33	-	-	-	-	-	-	-	-
IOLKFBCL_01609	1.18e-24	rfbA	2.7.7.24	-	H	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
IOLKFBCL_01611	8.31e-115	-	-	-	S	-	-	-	RloB-like protein
IOLKFBCL_01612	5.66e-235	-	-	-	S	ko:K06926	-	ko00000	AAA domain, putative AbiEii toxin, Type IV TA system
IOLKFBCL_01613	3.64e-30	-	-	-	S	-	-	-	enterobacterial common antigen metabolic process
IOLKFBCL_01614	8.49e-18	-	-	-	S	-	-	-	enterobacterial common antigen metabolic process
IOLKFBCL_01615	0.0	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.99
IOLKFBCL_01616	2.32e-314	wcoI	-	-	DM	-	-	-	Psort location CytoplasmicMembrane, score
IOLKFBCL_01617	2.28e-258	-	-	-	-	-	-	-	-
IOLKFBCL_01618	1.35e-216	-	-	-	S	ko:K21688	-	ko00000	G5
IOLKFBCL_01619	5.55e-79	trxA	1.8.1.9	-	O	ko:K00384,ko:K03671	ko00450,ko04621,ko05418,map00450,map04621,map05418	ko00000,ko00001,ko01000,ko03110	Belongs to the thioredoxin family
IOLKFBCL_01620	1.46e-162	-	-	-	F	-	-	-	Domain of unknown function (DUF4916)
IOLKFBCL_01621	8.16e-206	-	-	-	I	-	-	-	Alpha/beta hydrolase family
IOLKFBCL_01622	3.25e-292	nudC	3.6.1.22	-	L	ko:K03426	ko00760,ko01100,ko04146,map00760,map01100,map04146	ko00000,ko00001,ko01000	NADH pyrophosphatase zinc ribbon domain
IOLKFBCL_01623	1.66e-93	gcvH	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein
IOLKFBCL_01624	5.43e-152	-	-	-	L	-	-	-	Transposase
IOLKFBCL_01625	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
IOLKFBCL_01626	1.33e-160	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
IOLKFBCL_01627	1.4e-140	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
IOLKFBCL_01628	4.16e-44	-	-	-	S	ko:K07133	-	ko00000	AAA domain
IOLKFBCL_01629	7.11e-172	-	-	-	C	-	-	-	FMN binding
IOLKFBCL_01630	3e-124	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
IOLKFBCL_01631	5.1e-07	-	-	-	K	-	-	-	MerR, DNA binding
IOLKFBCL_01632	0.0	-	-	-	S	ko:K07133	-	ko00000	Domain of unknown function (DUF4143)
IOLKFBCL_01633	2.35e-243	adh	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Zinc-binding dehydrogenase
IOLKFBCL_01634	2.34e-21	-	-	-	K	-	-	-	MerR family regulatory protein
IOLKFBCL_01635	8.54e-24	-	-	-	K	-	-	-	MerR family regulatory protein
IOLKFBCL_01636	1.43e-112	-	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IOLKFBCL_01637	5.59e-78	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IOLKFBCL_01638	8.44e-39	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
IOLKFBCL_01639	1.69e-235	-	-	-	S	-	-	-	Conserved hypothetical protein 698
IOLKFBCL_01640	1.49e-185	-	-	-	K	-	-	-	Bacterial regulatory helix-turn-helix protein, lysR family
IOLKFBCL_01641	1.17e-127	tmp1	-	-	S	-	-	-	Domain of unknown function (DUF4391)
IOLKFBCL_01642	3.37e-292	tuf	-	-	J	ko:K02358	-	ko00000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
IOLKFBCL_01643	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IOLKFBCL_01644	1.9e-104	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
IOLKFBCL_01645	5.77e-81	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IOLKFBCL_01647	2.07e-240	-	-	-	S	ko:K03453	-	ko00000	SBF-like CPA transporter family (DUF4137)
IOLKFBCL_01649	2.18e-245	ltaE	4.1.2.48	-	E	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	Beta-eliminating lyase
IOLKFBCL_01650	2.78e-273	-	-	-	M	-	-	-	Glycosyl transferase 4-like domain
IOLKFBCL_01651	1.26e-240	-	2.6.1.1, 2.6.1.2, 2.6.1.66, 2.6.1.83	-	E	ko:K00812,ko:K08969,ko:K10206,ko:K14260,ko:K14261	ko00220,ko00250,ko00270,ko00290,ko00300,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00300,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class I and II
IOLKFBCL_01652	3.37e-296	purT	2.1.2.2	-	F	ko:K08289	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
IOLKFBCL_01653	4.25e-82	gloA	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IOLKFBCL_01654	9.74e-176	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
IOLKFBCL_01655	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	CobB/CobQ-like glutamine amidotransferase domain
IOLKFBCL_01656	2.5e-235	-	-	-	I	-	-	-	alpha/beta hydrolase fold
IOLKFBCL_01657	0.0	-	-	-	Q	-	-	-	D-alanine [D-alanyl carrier protein] ligase activity
IOLKFBCL_01658	7.04e-140	-	-	-	Q	-	-	-	D-alanine [D-alanyl carrier protein] ligase activity
IOLKFBCL_01659	9.34e-130	nnrE	-	-	L	-	-	-	Uracil DNA glycosylase superfamily
IOLKFBCL_01660	1.51e-215	-	2.7.11.1	-	S	ko:K07154	-	ko00000,ko01000,ko01001,ko02048	HipA N-terminal domain
IOLKFBCL_01661	5.22e-13	-	-	-	C	-	-	-	Aldo/keto reductase family
IOLKFBCL_01662	4.32e-58	-	-	-	C	-	-	-	Aldo/keto reductase family
IOLKFBCL_01663	9.47e-43	-	-	-	-	-	-	-	-
IOLKFBCL_01664	0.0	-	-	-	L	ko:K03502	-	ko00000,ko03400	DNA-damage repair protein (DNA polymerase IV) K00961
IOLKFBCL_01665	2.49e-243	-	3.3.1.1	-	H	ko:K01251	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	S-adenosyl-L-homocysteine hydrolase, NAD binding domain
IOLKFBCL_01666	1.91e-301	-	-	-	F	-	-	-	Amidohydrolase family
IOLKFBCL_01667	7.06e-86	-	-	-	S	ko:K09705	-	ko00000	Cupin superfamily (DUF985)
IOLKFBCL_01668	6.76e-163	-	-	-	ET	ko:K02030,ko:K02424,ko:K17073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Bacterial periplasmic substrate-binding proteins
IOLKFBCL_01669	3.2e-161	-	-	-	E	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOLKFBCL_01670	2.57e-153	-	3.6.3.21	-	E	ko:K02028,ko:K02029	-	ko00000,ko00002,ko01000,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
IOLKFBCL_01671	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
IOLKFBCL_01672	6.44e-240	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
IOLKFBCL_01673	1.15e-297	purD	6.3.3.1, 6.3.4.13	-	F	ko:K01945,ko:K11788	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
IOLKFBCL_01674	0.0	aldH	1.2.1.3, 1.2.99.10	-	C	ko:K00128,ko:K22445	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldehyde dehydrogenase family
IOLKFBCL_01675	0.0	-	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score 9.26
IOLKFBCL_01676	9.67e-200	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Zinc-uptake complex component A periplasmic
IOLKFBCL_01677	1.13e-127	-	-	-	S	-	-	-	cobalamin synthesis protein
IOLKFBCL_01678	8.31e-40	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal L28 family
IOLKFBCL_01679	5.79e-28	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L33
IOLKFBCL_01680	1.24e-58	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IOLKFBCL_01681	1.72e-45	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
IOLKFBCL_01682	4.34e-21	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L36
IOLKFBCL_01683	1.55e-27	-	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Ribosomal L32p protein family
IOLKFBCL_01684	1.17e-23	-	-	-	P	ko:K02077,ko:K09815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
IOLKFBCL_01685	1.89e-254	-	-	-	S	ko:K07089	-	ko00000	Predicted permease
IOLKFBCL_01686	2.69e-178	-	-	-	S	-	-	-	TIGRFAM TIGR03943 family protein
IOLKFBCL_01687	8.39e-73	fur	-	-	P	ko:K03711	-	ko00000,ko03000	Ferric uptake regulator family
IOLKFBCL_01688	3.43e-85	-	-	-	-	-	-	-	-
IOLKFBCL_01689	6.6e-58	-	-	-	K	-	-	-	Transcriptional regulator C-terminal region
IOLKFBCL_01690	5.88e-90	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
IOLKFBCL_01692	2.45e-59	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
IOLKFBCL_01693	7.7e-95	fur	-	-	P	ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
IOLKFBCL_01694	4.92e-286	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IOLKFBCL_01695	8.44e-111	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
IOLKFBCL_01696	6.77e-223	yogA	-	-	C	-	-	-	Zinc-binding dehydrogenase
IOLKFBCL_01697	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
IOLKFBCL_01698	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
IOLKFBCL_01699	4.06e-185	-	-	-	M	-	-	-	Conserved repeat domain
IOLKFBCL_01700	3.61e-157	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
IOLKFBCL_01703	5.97e-267	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative ATP-dependent DNA helicase recG C-terminal
IOLKFBCL_01704	8.77e-203	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
IOLKFBCL_01705	0.0	-	-	-	G	-	-	-	Alpha-L-arabinofuranosidase C-terminal domain
IOLKFBCL_01706	2.01e-48	-	-	-	-	-	-	-	-
IOLKFBCL_01707	2.61e-19	-	-	-	P	-	-	-	Citrate transporter
IOLKFBCL_01708	0.0	-	-	-	EK	ko:K03710,ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	ko00000,ko00001,ko01000,ko03000	Alanine-glyoxylate amino-transferase
IOLKFBCL_01709	4.17e-149	pdxT	4.3.3.6	-	H	ko:K08681	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
IOLKFBCL_01710	1.9e-198	pdxS	4.3.3.6	-	H	ko:K06215	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
IOLKFBCL_01711	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
IOLKFBCL_01712	4.87e-313	dgt	3.1.5.1	-	F	ko:K01129	ko00230,map00230	ko00000,ko00001,ko01000	Phosphohydrolase-associated domain
IOLKFBCL_01713	2.12e-315	alr	5.1.1.1	-	M	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IOLKFBCL_01714	0.0	aap1	-	-	E	ko:K03294	-	ko00000	aromatic amino acid transport protein AroP K03293
IOLKFBCL_01715	1.45e-131	cysE	-	-	J	-	-	-	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IOLKFBCL_01716	2.77e-119	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
IOLKFBCL_01717	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
IOLKFBCL_01718	0.0	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
IOLKFBCL_01719	1.84e-282	metB	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Cys/Met metabolism PLP-dependent enzyme
IOLKFBCL_01720	1.17e-118	cbs	2.5.1.47, 4.2.1.22	-	E	ko:K01697,ko:K01738	ko00260,ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Pyridoxal-phosphate dependent enzyme
IOLKFBCL_01721	0.000141	-	-	-	F	-	-	-	Amidohydrolase family
IOLKFBCL_01722	7.91e-225	-	-	-	EGP	ko:K08168	-	ko00000,ko00002,ko01504,ko02000	Major Facilitator Superfamily
IOLKFBCL_01723	8.01e-193	iunH2	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Inosine-uridine preferring nucleoside hydrolase
IOLKFBCL_01725	3.28e-154	-	-	-	EP	ko:K02031	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	oligopeptide transport protein of the ABC superfamily, ATP-binding component
IOLKFBCL_01726	1.71e-180	-	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOLKFBCL_01727	1.38e-206	-	-	-	P	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOLKFBCL_01728	0.0	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, family 5
IOLKFBCL_01729	1.38e-308	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IOLKFBCL_01730	4.65e-181	coaX	2.7.1.33	-	H	ko:K03525	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
IOLKFBCL_01731	0.0	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
IOLKFBCL_01732	0.0	bga1	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
IOLKFBCL_01733	7.33e-143	-	5.4.99.28, 5.4.99.29	-	J	ko:K06177	-	ko00000,ko01000,ko03009,ko03016	RNA pseudouridylate synthase
IOLKFBCL_01734	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
IOLKFBCL_01735	2.91e-190	tcyC	3.6.3.21	-	E	ko:K02028,ko:K02029	-	ko00000,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
IOLKFBCL_01736	2.85e-218	yecS	-	-	E	ko:K02029	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOLKFBCL_01737	6.22e-216	glnH	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter, substrate-binding protein, family 3
IOLKFBCL_01738	1.4e-213	glnH	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter, substrate-binding protein, family 3
IOLKFBCL_01739	8.01e-107	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
IOLKFBCL_01740	5.86e-263	-	-	-	D	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	CHAP domain protein
IOLKFBCL_01741	3.68e-204	ftsX	-	-	D	ko:K09811	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Part of the ABC transporter FtsEX involved in cellular division
IOLKFBCL_01742	2.61e-234	ftsE	-	-	D	ko:K09812	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Cell division ATP-binding protein FtsE
IOLKFBCL_01743	3.59e-263	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
IOLKFBCL_01744	0.0	-	-	-	S	ko:K07133	-	ko00000	Domain of unknown function (DUF4143)
IOLKFBCL_01745	0.0	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
IOLKFBCL_01746	1.07e-158	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
IOLKFBCL_01747	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IOLKFBCL_01748	4.07e-131	-	-	-	P	ko:K02025,ko:K05814	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOLKFBCL_01749	7.79e-124	-	-	-	G	ko:K02026,ko:K05815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOLKFBCL_01750	2.99e-200	-	-	-	G	ko:K05813	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
IOLKFBCL_01751	2.94e-126	-	-	-	C	-	-	-	Domain of unknown function
IOLKFBCL_01752	0.0	pepN	3.4.11.2	-	E	ko:K01256,ko:K08776	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	Peptidase family M1 domain
IOLKFBCL_01753	0.0	rnj	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IOLKFBCL_01754	8.94e-213	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IOLKFBCL_01755	1.26e-167	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
IOLKFBCL_01756	6.14e-297	-	-	-	G	-	-	-	Major Facilitator Superfamily
IOLKFBCL_01757	0.0	uvrD2	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	Belongs to the helicase family. UvrD subfamily
IOLKFBCL_01758	0.0	-	-	-	L	-	-	-	PD-(D/E)XK nuclease superfamily
IOLKFBCL_01759	0.0	pknK	2.7.11.1	-	KLT	ko:K12132	-	ko00000,ko01000,ko01001	Protein tyrosine kinase
IOLKFBCL_01760	0.0	-	-	-	S	-	-	-	Fibronectin type 3 domain
IOLKFBCL_01761	3.15e-233	-	-	-	S	ko:K03924	-	ko00000,ko01000	ATPase family associated with various cellular activities (AAA)
IOLKFBCL_01762	2.52e-282	-	-	-	S	-	-	-	Protein of unknown function DUF58
IOLKFBCL_01763	0.0	-	-	-	E	-	-	-	Transglutaminase-like superfamily
IOLKFBCL_01764	1.54e-05	-	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	Sigma factor PP2C-like phosphatases
IOLKFBCL_01765	1.05e-31	-	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	Sigma factor PP2C-like phosphatases
IOLKFBCL_01766	1.44e-100	-	-	-	B	-	-	-	Belongs to the OprB family
IOLKFBCL_01767	8.85e-117	-	-	-	T	-	-	-	Forkhead associated domain
IOLKFBCL_01768	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IOLKFBCL_01769	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IOLKFBCL_01770	2.14e-149	-	-	-	-	-	-	-	-
IOLKFBCL_01771	2.52e-235	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	FES
IOLKFBCL_01772	9.47e-149	spoU	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
IOLKFBCL_01773	3.82e-52	-	-	-	DJ	ko:K06218	-	ko00000,ko02048	ParE toxin of type II toxin-antitoxin system, parDE
IOLKFBCL_01774	1.28e-45	-	-	-	S	ko:K18918	-	ko00000,ko02048,ko03000	CopG domain protein DNA-binding domain protein
IOLKFBCL_01776	1.27e-24	-	-	-	Q	-	-	-	Belongs to the P-Pant transferase superfamily
IOLKFBCL_01777	3.38e-159	-	-	-	U	ko:K08369	-	ko00000,ko02000	Sugar (and other) transporter
IOLKFBCL_01778	2.08e-284	-	-	-	M	-	-	-	Belongs to the D-alanine--D-alanine ligase family
IOLKFBCL_01779	1.68e-26	-	-	-	Q	-	-	-	COG1020 Non-ribosomal peptide synthetase modules and related proteins
IOLKFBCL_01780	1.25e-41	-	-	-	Q	ko:K13611,ko:K13614	-	ko00000,ko01004,ko01008	Non-ribosomal peptide synthetase modules and related proteins
IOLKFBCL_01781	8.02e-277	-	-	-	P	-	-	-	Major Facilitator Superfamily
IOLKFBCL_01782	5.65e-51	-	-	-	S	ko:K06921	-	ko00000	ATPase domain predominantly from Archaea
IOLKFBCL_01783	7.8e-29	-	-	-	S	ko:K06921	-	ko00000	ATPase domain predominantly from Archaea
IOLKFBCL_01784	4.31e-168	-	-	-	S	ko:K06921	-	ko00000	ATPase domain predominantly from Archaea
IOLKFBCL_01785	0.0	-	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
IOLKFBCL_01786	1.13e-58	-	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
IOLKFBCL_01787	0.0	-	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 32 family
IOLKFBCL_01788	9.48e-242	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
IOLKFBCL_01789	3.11e-130	-	-	-	S	-	-	-	Protein of unknown function, DUF624
IOLKFBCL_01790	2.26e-216	-	-	-	G	ko:K17320	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOLKFBCL_01791	1.14e-218	-	-	-	G	ko:K17319	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOLKFBCL_01792	2.67e-111	-	-	-	G	ko:K17318	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
IOLKFBCL_01793	5.28e-204	-	-	-	G	ko:K17318	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
IOLKFBCL_01794	1.65e-267	-	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Drug resistance MFS transporter, drug H antiporter-2 family
IOLKFBCL_01795	2.92e-297	galK	2.7.1.6, 2.7.7.12	-	G	ko:K00849,ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GHMP kinase family. GalK subfamily
IOLKFBCL_01796	0.0	galT	2.7.7.12	-	C	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	Galactose-1-phosphate uridyl transferase, N-terminal domain
IOLKFBCL_01797	1.03e-157	-	-	-	K	-	-	-	DeoR C terminal sensor domain
IOLKFBCL_01798	1.71e-286	pyrD	1.3.5.2, 1.3.98.1	-	F	ko:K00226,ko:K00254	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor
IOLKFBCL_01799	9.1e-317	namA	-	-	C	-	-	-	NADH:flavin oxidoreductase / NADH oxidase family
IOLKFBCL_01800	0.0	pon1	-	-	M	-	-	-	Transglycosylase
IOLKFBCL_01801	1.23e-168	crp	-	-	K	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	ko00000,ko00001,ko03000	helix_turn_helix, cAMP Regulatory protein
IOLKFBCL_01802	2.12e-253	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Biotin/lipoate A/B protein ligase family
IOLKFBCL_01803	3.1e-246	leuB	1.1.1.85	-	CE	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
IOLKFBCL_01804	0.0	ptrB	3.4.21.83	-	E	ko:K01354	ko05142,ko05143,map05142,map05143	ko00000,ko00001,ko01000,ko01002	Peptidase, S9A B C family, catalytic domain protein
IOLKFBCL_01805	0.0	-	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2183)
IOLKFBCL_01806	5.99e-274	-	-	-	L	ko:K07496	-	ko00000	Helix-turn-helix domain
IOLKFBCL_01807	1.12e-131	-	-	-	L	ko:K07450	-	ko00000	Resolvase, N terminal domain
IOLKFBCL_01808	9.48e-237	-	-	-	V	-	-	-	Abi-like protein
IOLKFBCL_01809	1.77e-177	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
IOLKFBCL_01810	4.57e-11	-	-	-	L	-	-	-	Transposase, Mutator family
IOLKFBCL_01812	1.05e-07	-	-	-	-	-	-	-	-
IOLKFBCL_01814	1.71e-42	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF961)
IOLKFBCL_01815	1.43e-96	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
IOLKFBCL_01816	6.99e-31	-	-	-	D	-	-	-	COG COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
IOLKFBCL_01817	2.25e-192	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
IOLKFBCL_01818	2.44e-134	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
IOLKFBCL_01819	4.49e-145	-	-	-	-	-	-	-	-
IOLKFBCL_01820	4.19e-155	-	-	-	-	-	-	-	-
IOLKFBCL_01821	1.81e-30	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
IOLKFBCL_01822	3.66e-114	mutF	-	-	V	ko:K01990,ko:K20490	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter ATP-binding
IOLKFBCL_01823	1.28e-76	mutE	-	-	S	ko:K20491	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
IOLKFBCL_01824	1.88e-73	mutG	-	-	S	ko:K20492	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	Lantibiotic protection ABC transporter permease subunit, MutG family
IOLKFBCL_01825	1.13e-113	-	-	-	-	ko:K20489	ko02020,ko02024,map02020,map02024	ko00000,ko00001	-
IOLKFBCL_01826	2.79e-126	-	-	-	T	ko:K20488	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
IOLKFBCL_01827	7.61e-145	-	2.7.13.3	-	T	ko:K20487	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	subtilin biosynthesis sensor protein SpaK
IOLKFBCL_01828	1.59e-129	-	-	-	-	-	-	-	-
IOLKFBCL_01829	8.67e-205	-	-	-	EG	-	-	-	EamA-like transporter family
IOLKFBCL_01830	3.34e-92	pdxH	-	-	S	ko:K07006	-	ko00000	Pfam:Pyridox_oxidase
IOLKFBCL_01831	7.16e-297	-	-	-	L	-	-	-	ribosomal rna small subunit methyltransferase
IOLKFBCL_01832	1.31e-209	gpmB	3.1.3.85, 5.4.2.11	-	G	ko:K01834,ko:K22306	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Phosphoglycerate mutase family
IOLKFBCL_01833	1.16e-216	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
IOLKFBCL_01834	1.56e-192	-	-	-	ET	ko:K10005	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
IOLKFBCL_01835	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
IOLKFBCL_01836	1.05e-98	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Helix-hairpin-helix motif
IOLKFBCL_01837	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein
IOLKFBCL_01838	2.48e-226	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
IOLKFBCL_01839	9.29e-132	tsaE	-	-	S	ko:K06925	-	ko00000,ko03016	Threonylcarbamoyl adenosine biosynthesis protein TsaE
IOLKFBCL_01840	1.29e-191	yeaZ	-	-	O	ko:K14742	-	ko00000,ko03016	Glycoprotease family
IOLKFBCL_01841	1.52e-127	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	FR47-like protein
IOLKFBCL_01842	7.64e-249	tsaD	2.3.1.234	-	O	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IOLKFBCL_01845	2.35e-95	-	-	-	-	-	-	-	-
IOLKFBCL_01846	1.01e-199	-	-	-	S	-	-	-	Putative amidase domain
IOLKFBCL_01847	4.88e-181	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
IOLKFBCL_01848	4.98e-213	-	-	-	K	-	-	-	Transposase IS116 IS110 IS902
IOLKFBCL_01849	4.9e-27	-	-	-	S	-	-	-	SdpI/YhfL protein family
IOLKFBCL_01852	1.29e-45	-	-	-	I	-	-	-	radical SAM domain protein
IOLKFBCL_01855	2e-120	-	-	-	V	ko:K06147	-	ko00000,ko02000	ATPases associated with a variety of cellular activities
IOLKFBCL_01856	2.11e-80	-	-	-	U	ko:K03205	ko03070,map03070	ko00000,ko00001,ko00002,ko02044	Type IV secretory system Conjugative DNA transfer
IOLKFBCL_01857	1.4e-26	-	-	-	L	-	-	-	Phage integrase family
IOLKFBCL_01861	1.86e-72	-	-	-	S	-	-	-	Fic/DOC family
IOLKFBCL_01863	8.36e-14	-	-	-	-	-	-	-	-
IOLKFBCL_01864	1.7e-46	-	-	-	-	-	-	-	-
IOLKFBCL_01865	3.52e-221	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
IOLKFBCL_01866	3.1e-57	-	-	-	L	-	-	-	PFAM Relaxase mobilization nuclease family protein
IOLKFBCL_01867	1.55e-252	-	-	-	V	ko:K20459	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
IOLKFBCL_01868	2.53e-181	-	-	-	S	ko:K20460	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
IOLKFBCL_01869	6.95e-183	-	-	-	-	ko:K20461	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	-
IOLKFBCL_01870	3.84e-91	-	-	-	-	-	-	-	-
IOLKFBCL_01872	4.55e-303	-	-	-	T	-	-	-	Histidine kinase
IOLKFBCL_01873	5.21e-155	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
IOLKFBCL_01875	1.44e-137	-	-	-	M	-	-	-	Peptidase family M23
IOLKFBCL_01876	0.0	-	-	-	G	-	-	-	ABC transporter substrate-binding protein
IOLKFBCL_01877	1.11e-305	icd	1.1.1.42	-	C	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the isocitrate and isopropylmalate dehydrogenases family
IOLKFBCL_01878	1.07e-264	guaB3	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	IMP dehydrogenase family protein
IOLKFBCL_01879	1.98e-91	-	-	-	-	-	-	-	-
IOLKFBCL_01880	0.0	fadD3	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	long-chain-fatty acid CoA ligase
IOLKFBCL_01881	4.26e-113	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
IOLKFBCL_01882	1.37e-186	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
IOLKFBCL_01883	2.17e-184	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
IOLKFBCL_01884	4.09e-166	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
IOLKFBCL_01885	1.86e-115	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
IOLKFBCL_01886	1.03e-216	cdsA	2.7.7.41	-	I	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Cytidylyltransferase family
IOLKFBCL_01887	7.52e-284	rlmN	2.1.1.192	-	J	ko:K06941	-	ko00000,ko01000,ko03009	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
IOLKFBCL_01888	3.87e-96	-	3.5.1.124	-	S	ko:K05520	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
IOLKFBCL_01889	5.87e-180	hisF	4.1.3.27	-	E	ko:K01657,ko:K02500	ko00340,ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00340,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
IOLKFBCL_01890	2.31e-91	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
IOLKFBCL_01891	0.0	trpE	4.1.3.27	-	E	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IOLKFBCL_01892	8.02e-144	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
IOLKFBCL_01893	2.6e-209	-	-	-	S	-	-	-	Protein of unknown function (DUF979)
IOLKFBCL_01894	7.79e-153	-	-	-	S	-	-	-	Protein of unknown function (DUF969)
IOLKFBCL_01895	0.0	ybiT	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter
IOLKFBCL_01896	1.44e-165	-	-	-	S	-	-	-	Enoyl-(Acyl carrier protein) reductase
IOLKFBCL_01897	1.47e-207	-	-	-	S	-	-	-	Protein conserved in bacteria
IOLKFBCL_01898	6.76e-84	-	-	-	S	-	-	-	Zincin-like metallopeptidase
IOLKFBCL_01899	1.49e-41	-	-	-	G	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
IOLKFBCL_01900	1.22e-17	-	-	-	S	ko:K16926	-	ko00000,ko00002,ko02000	Hypothetical bacterial integral membrane protein (Trep_Strep)
IOLKFBCL_01901	4.88e-152	-	2.7.13.3	-	T	ko:K18351	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
IOLKFBCL_01902	2.48e-149	-	-	-	K	-	-	-	Transcriptional regulatory protein, C terminal
IOLKFBCL_01903	2.39e-187	-	-	-	-	-	-	-	-
IOLKFBCL_01904	1.15e-187	-	-	-	M	-	-	-	Putative peptidoglycan binding domain
IOLKFBCL_01905	2.58e-177	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
IOLKFBCL_01906	2.08e-207	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
IOLKFBCL_01907	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
IOLKFBCL_01908	5.2e-147	-	-	-	S	-	-	-	Domain of unknown function (DUF4194)
IOLKFBCL_01909	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
IOLKFBCL_01910	2.87e-16	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
IOLKFBCL_01911	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
IOLKFBCL_01912	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
IOLKFBCL_01913	2.62e-237	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Shikimate dehydrogenase substrate binding domain
IOLKFBCL_01914	1.29e-235	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
IOLKFBCL_01915	1.42e-217	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
IOLKFBCL_01916	1.84e-281	pgk	2.7.2.3, 5.3.1.1	-	F	ko:K00927,ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Phosphoglycerate kinase
IOLKFBCL_01917	7.71e-186	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
IOLKFBCL_01918	2.51e-47	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase SecG subunit
IOLKFBCL_01919	3.95e-224	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
IOLKFBCL_01920	2.17e-209	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
IOLKFBCL_01921	7.96e-317	aspC	2.6.1.1, 2.6.1.2, 2.6.1.66	-	E	ko:K00812,ko:K14260	ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I II
IOLKFBCL_01922	2.16e-276	-	-	-	V	-	-	-	MatE
IOLKFBCL_01923	2.15e-272	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
IOLKFBCL_01924	3.03e-256	tal	2.2.1.2	-	H	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IOLKFBCL_01925	0.0	tkt	2.2.1.1	-	H	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the transketolase family
IOLKFBCL_01926	4.28e-238	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
IOLKFBCL_01927	3.8e-273	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
IOLKFBCL_01928	1.07e-199	-	-	-	G	-	-	-	Fructosamine kinase
IOLKFBCL_01929	1.14e-196	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
IOLKFBCL_01930	8.61e-206	-	-	-	S	-	-	-	PAC2 family
IOLKFBCL_01936	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IOLKFBCL_01937	5.37e-143	-	2.7.7.53	-	FG	ko:K19710	ko00230,map00230	ko00000,ko00001,ko01000	HIT domain
IOLKFBCL_01938	3.41e-156	yebC	-	-	K	-	-	-	transcriptional regulatory protein
IOLKFBCL_01939	1.58e-126	ruvC	3.1.22.4	-	L	ko:K01159	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
IOLKFBCL_01940	4.97e-114	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
IOLKFBCL_01941	3.32e-242	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
IOLKFBCL_01942	4.71e-51	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit
IOLKFBCL_01943	3.96e-115	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IOLKFBCL_01944	4.58e-270	sucC	6.2.1.5	-	F	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
IOLKFBCL_01945	2.48e-200	sucD	6.2.1.5	-	C	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
IOLKFBCL_01946	1.97e-310	-	-	-	-	-	-	-	-
IOLKFBCL_01947	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
IOLKFBCL_01948	1.69e-41	-	-	-	-	-	-	-	-
IOLKFBCL_01949	6.05e-206	-	-	-	U	ko:K06188	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
IOLKFBCL_01950	1.29e-183	rluB	5.4.99.19, 5.4.99.22	-	J	ko:K06178,ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
IOLKFBCL_01951	0.0	der	-	-	F	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
IOLKFBCL_01953	0.0	ugp	2.7.7.9	-	G	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
IOLKFBCL_01954	0.0	-	-	-	K	-	-	-	WYL domain
IOLKFBCL_01955	7.59e-64	-	-	-	-	-	-	-	-
IOLKFBCL_01956	0.0	helY	-	-	L	ko:K03727	-	ko00000,ko01000	DEAD DEAH box helicase
IOLKFBCL_01957	6.43e-81	rbpA	-	-	K	-	-	-	Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters
IOLKFBCL_01958	1.96e-165	nt5e	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	HAD-hyrolase-like
IOLKFBCL_01959	3.46e-50	-	-	-	-	-	-	-	-
IOLKFBCL_01960	8.45e-96	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
IOLKFBCL_01962	3.63e-99	-	-	-	S	-	-	-	N-methyltransferase activity
IOLKFBCL_01963	4.85e-42	-	-	-	L	-	-	-	Transposase
IOLKFBCL_01966	2.65e-30	hipA	2.7.11.1	-	S	ko:K07154	-	ko00000,ko01000,ko01001,ko02048	HipA N-terminal domain protein
IOLKFBCL_01968	2.05e-164	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
IOLKFBCL_01970	2.34e-56	hrtA	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
IOLKFBCL_01972	2.66e-74	-	-	-	-	-	-	-	-
IOLKFBCL_01973	6.65e-145	merR2	-	-	K	-	-	-	helix_turn_helix, mercury resistance
IOLKFBCL_01974	1.17e-96	garA	-	-	T	-	-	-	Inner membrane component of T3SS, cytoplasmic domain
IOLKFBCL_01975	1.03e-177	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF881)
IOLKFBCL_01976	7.03e-51	sbp	-	-	S	-	-	-	Protein of unknown function (DUF1290)
IOLKFBCL_01977	1.5e-196	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF881)
IOLKFBCL_01978	7.77e-137	pgsA2	2.7.8.41, 2.7.8.5	-	I	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IOLKFBCL_01979	1.84e-201	hisG	2.4.2.17	-	F	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	ATP phosphoribosyltransferase
IOLKFBCL_01980	3.56e-56	hisE	3.6.1.31	-	E	ko:K01523	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Phosphoribosyl-ATP pyrophosphohydrolase
IOLKFBCL_01981	4.64e-151	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribulose-phosphate 3-epimerase
IOLKFBCL_01982	4.02e-237	lgt	-	-	M	-	-	-	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
IOLKFBCL_01983	7.76e-202	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
IOLKFBCL_01984	0.0	trpB	4.2.1.20	-	E	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
IOLKFBCL_01985	1.84e-170	-	-	-	S	-	-	-	SOS response associated peptidase (SRAP)
IOLKFBCL_01986	1.51e-198	nfo	3.1.21.2	-	L	ko:K01151	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
IOLKFBCL_01987	0.0	-	-	-	E	ko:K16235	-	ko00000,ko02000	amino acid
IOLKFBCL_01988	3.21e-111	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
IOLKFBCL_01989	1.47e-241	-	-	-	V	-	-	-	VanZ like family
IOLKFBCL_01990	4.21e-63	cefD	5.1.1.17	-	E	ko:K04127	ko00311,ko01100,ko01130,map00311,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Aminotransferase, class V
IOLKFBCL_01991	7.82e-118	-	-	-	K	-	-	-	FR47-like protein
IOLKFBCL_01992	2.03e-33	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2316)
IOLKFBCL_01993	6.4e-129	-	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
IOLKFBCL_01994	3.82e-36	-	-	-	L	-	-	-	Transposase DDE domain
IOLKFBCL_01995	0.0	-	-	-	E	ko:K03307	-	ko00000	Sodium:solute symporter family
IOLKFBCL_01996	9.29e-57	-	-	-	-	-	-	-	-
IOLKFBCL_01997	4.94e-109	-	-	-	G	ko:K02445,ko:K03762	-	ko00000,ko02000	transmembrane transporter activity
IOLKFBCL_01998	2.1e-09	truD	5.4.99.27	-	J	ko:K06176	-	ko00000,ko01000,ko03016	Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs
IOLKFBCL_01999	3.1e-59	-	-	-	L	-	-	-	Transposase DDE domain
IOLKFBCL_02000	3.52e-61	-	-	-	-	-	-	-	-
IOLKFBCL_02001	1.39e-155	-	-	-	-	-	-	-	-
IOLKFBCL_02004	3.05e-61	-	-	-	T	-	-	-	Histidine kinase
IOLKFBCL_02005	1.82e-258	-	-	-	T	-	-	-	Histidine kinase
IOLKFBCL_02006	3.69e-166	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
IOLKFBCL_02007	5.1e-125	-	-	-	-	-	-	-	-
IOLKFBCL_02008	4.14e-200	-	-	-	M	-	-	-	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IOLKFBCL_02009	1.75e-157	-	-	-	Q	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
IOLKFBCL_02010	3.18e-234	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
IOLKFBCL_02011	1.49e-53	-	-	-	L	ko:K07473	-	ko00000,ko02048	RelB antitoxin
IOLKFBCL_02012	2.98e-64	-	-	-	S	ko:K19157	-	ko00000,ko01000,ko02048	Bacterial toxin of type II toxin-antitoxin system, YafQ
IOLKFBCL_02013	6.23e-35	-	-	-	G	-	-	-	Transporter major facilitator family protein
IOLKFBCL_02014	0.0	-	-	-	E	ko:K16235	-	ko00000,ko02000	amino acid
IOLKFBCL_02016	3.35e-116	-	-	-	EGP	-	-	-	Transporter, major facilitator family protein
IOLKFBCL_02017	2.54e-266	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
IOLKFBCL_02018	1.1e-190	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IOLKFBCL_02019	1.23e-188	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
IOLKFBCL_02020	6.79e-79	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
IOLKFBCL_02022	0.0	-	-	-	P	ko:K02050	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOLKFBCL_02023	0.0	-	-	-	P	ko:K02049	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
IOLKFBCL_02024	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
IOLKFBCL_02027	3.33e-220	-	-	-	S	ko:K07088	-	ko00000	Auxin Efflux Carrier
IOLKFBCL_02028	5.57e-307	-	-	-	V	ko:K12554	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Psort location Cytoplasmic, score 8.87
IOLKFBCL_02029	3.97e-312	-	-	-	V	ko:K12554	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Psort location Cytoplasmic, score 8.87
IOLKFBCL_02030	4.58e-288	-	-	-	V	ko:K12554	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Psort location Cytoplasmic, score 8.87
IOLKFBCL_02032	2.87e-169	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
IOLKFBCL_02033	2.22e-185	rph	2.7.7.56	-	J	ko:K00989	-	ko00000,ko01000,ko03016	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
IOLKFBCL_02034	5.53e-206	-	-	-	-	-	-	-	-
IOLKFBCL_02035	1.4e-314	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
IOLKFBCL_02036	1.71e-155	-	-	-	-	-	-	-	-
IOLKFBCL_02037	7.11e-91	-	-	-	K	-	-	-	MerR, DNA binding
IOLKFBCL_02038	4.06e-243	-	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo/keto reductase family
IOLKFBCL_02039	3.9e-69	-	-	-	S	-	-	-	Protein of unknown function (DUF3039)
IOLKFBCL_02040	2.45e-114	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
IOLKFBCL_02041	5.73e-175	-	-	-	-	-	-	-	-
IOLKFBCL_02042	8.82e-154	-	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
IOLKFBCL_02043	3.14e-42	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
IOLKFBCL_02044	5.2e-167	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
IOLKFBCL_02045	0.0	ilvB	2.2.1.6	-	H	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Thiamine pyrophosphate enzyme, central domain
IOLKFBCL_02046	5.15e-118	ilvN	2.2.1.6	-	E	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	ACT domain
IOLKFBCL_02047	3.08e-57	-	-	-	S	ko:K21495	-	ko00000,ko02048	Plasmid stability protein
IOLKFBCL_02048	9.76e-83	vapC	-	-	S	ko:K07062	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module. An RNase
IOLKFBCL_02049	0.0	yjjK	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter
IOLKFBCL_02050	1.07e-174	-	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Peptidase C26
IOLKFBCL_02051	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
IOLKFBCL_02052	4.51e-207	-	-	-	P	-	-	-	Cation efflux family
IOLKFBCL_02053	0.0	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IOLKFBCL_02054	8.12e-230	-	-	-	S	-	-	-	Endonuclease/Exonuclease/phosphatase family
IOLKFBCL_02055	1.76e-104	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
IOLKFBCL_02056	5.44e-299	ribBA	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IOLKFBCL_02057	2.51e-144	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Lumazine binding domain
IOLKFBCL_02058	1.79e-268	ribD	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IOLKFBCL_02059	0.0	pabB	2.6.1.85, 4.1.3.27, 4.1.3.38	-	EH	ko:K01657,ko:K01665,ko:K03342,ko:K13950	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000,ko01007	chorismate binding enzyme
IOLKFBCL_02060	1.28e-183	pabC	2.6.1.42, 2.6.1.85, 4.1.3.38	-	E	ko:K00826,ko:K01665,ko:K02619,ko:K03342	ko00270,ko00280,ko00290,ko00770,ko00790,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map00790,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	branched-chain-amino-acid transaminase activity
IOLKFBCL_02061	1.66e-83	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
IOLKFBCL_02062	1.24e-47	-	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
IOLKFBCL_02063	9.5e-142	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IOLKFBCL_02064	3.36e-61	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
IOLKFBCL_02065	3.61e-226	-	2.7.11.1	-	S	ko:K07154	-	ko00000,ko01000,ko01001,ko02048	Pfam:HipA_N
IOLKFBCL_02066	3.74e-276	-	-	-	-	-	-	-	-
IOLKFBCL_02067	7.48e-143	-	-	-	U	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOLKFBCL_02068	6.88e-152	-	-	-	U	ko:K02025,ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOLKFBCL_02069	1.61e-176	-	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
IOLKFBCL_02070	2.08e-153	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
IOLKFBCL_02071	4.43e-250	-	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Inosine-uridine preferring nucleoside hydrolase
IOLKFBCL_02072	4.08e-216	-	-	-	C	-	-	-	Oxidoreductase, aldo keto reductase family protein
IOLKFBCL_02073	1.32e-24	-	-	-	-	-	-	-	-
IOLKFBCL_02074	4.95e-210	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
IOLKFBCL_02075	1.1e-16	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
IOLKFBCL_02076	0.0	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
IOLKFBCL_02077	1.03e-121	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
IOLKFBCL_02078	3.17e-190	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
IOLKFBCL_02079	2.32e-215	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease
IOLKFBCL_02080	3.53e-207	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
IOLKFBCL_02081	1.09e-238	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import
IOLKFBCL_02082	1.68e-179	regX3	-	-	KT	ko:K07776	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
IOLKFBCL_02083	1.89e-258	phoR	2.7.13.3	-	T	ko:K07636,ko:K07768	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	His Kinase A (phosphoacceptor) domain
IOLKFBCL_02084	2.91e-294	-	-	-	EGP	-	-	-	Sugar (and other) transporter
IOLKFBCL_02085	5.79e-157	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IOLKFBCL_02086	6.38e-298	aroG	2.5.1.54	-	E	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	ko00000,ko00001,ko00002,ko01000	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IOLKFBCL_02087	1.27e-269	aroG	2.5.1.54	-	E	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	ko00000,ko00001,ko00002,ko01000	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IOLKFBCL_02088	0.0	pepC2	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
IOLKFBCL_02089	7.13e-155	-	-	-	D	-	-	-	nuclear chromosome segregation
IOLKFBCL_02090	1.97e-158	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
IOLKFBCL_02091	2.62e-205	ispD	1.1.1.405, 2.7.7.40, 2.7.7.60	-	I	ko:K00991,ko:K21681	ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
IOLKFBCL_02092	5.04e-232	yfiH	-	-	Q	ko:K05810	-	ko00000,ko01000	Multi-copper polyphenol oxidoreductase laccase
IOLKFBCL_02093	0.0	-	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Peptidase family U32 C-terminal domain
IOLKFBCL_02094	4.51e-196	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
IOLKFBCL_02095	3.17e-135	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	Conserved hypothetical protein 95
IOLKFBCL_02096	6.25e-74	-	-	-	L	-	-	-	Transposase DDE domain
IOLKFBCL_02098	1.98e-34	-	-	-	V	-	-	-	Type II restriction enzyme, methylase subunits
IOLKFBCL_02100	2.19e-250	-	-	-	G	-	-	-	Hypothetical glycosyl hydrolase 6
IOLKFBCL_02101	7.62e-126	-	-	-	EGP	-	-	-	Transporter, major facilitator family protein
IOLKFBCL_02102	1.08e-27	-	4.2.1.68	-	M	ko:K18334	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Enolase C-terminal domain-like
IOLKFBCL_02103	1.03e-60	-	4.2.1.68	-	M	ko:K18334	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Enolase C-terminal domain-like
IOLKFBCL_02104	1.07e-204	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
IOLKFBCL_02105	5.99e-219	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOLKFBCL_02106	3.29e-205	-	-	-	P	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOLKFBCL_02107	6.42e-89	-	-	-	K	ko:K02529	-	ko00000,ko03000	Bacterial regulatory proteins, lacI family
IOLKFBCL_02108	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	helicase superfamily c-terminal domain
IOLKFBCL_02109	3.03e-40	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal L28 family
IOLKFBCL_02110	3.78e-249	-	-	-	G	-	-	-	pfkB family carbohydrate kinase
IOLKFBCL_02111	5.42e-293	-	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	Vacuole effluxer Atg22 like
IOLKFBCL_02112	1.21e-245	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
IOLKFBCL_02113	3.04e-32	-	-	-	-	-	-	-	-
IOLKFBCL_02114	5.7e-15	-	-	-	S	-	-	-	Alpha/beta hydrolase family
IOLKFBCL_02115	3.73e-33	yxiO	-	-	G	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	Major facilitator Superfamily
IOLKFBCL_02120	3.38e-15	-	-	-	S	ko:K19784	-	ko00000	NADPH-dependent FMN reductase
IOLKFBCL_02121	2.65e-110	ogt	2.1.1.63	-	L	ko:K00567,ko:K07443	-	ko00000,ko01000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IOLKFBCL_02122	1.93e-305	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
IOLKFBCL_02123	1.56e-173	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
IOLKFBCL_02124	0.0	aspA	4.3.1.1	-	E	ko:K01744	ko00250,ko01100,map00250,map01100	ko00000,ko00001,ko01000	Fumarase C C-terminus
IOLKFBCL_02125	1.6e-177	-	-	-	M	-	-	-	Mechanosensitive ion channel
IOLKFBCL_02126	9.53e-226	-	-	-	S	-	-	-	CAAX protease self-immunity
IOLKFBCL_02127	2.79e-292	-	-	-	E	ko:K02052	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
IOLKFBCL_02128	5.75e-169	-	-	-	U	ko:K02053	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOLKFBCL_02129	1.13e-202	-	-	-	U	ko:K02054	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOLKFBCL_02130	7.04e-267	-	-	-	P	ko:K02055	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
IOLKFBCL_02131	1.17e-290	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
IOLKFBCL_02132	3.96e-228	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus
IOLKFBCL_02133	8.32e-229	plsC2	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Phosphate acyltransferases
IOLKFBCL_02134	1.33e-82	psp1	3.5.99.10	-	J	ko:K09022	-	ko00000,ko01000	Endoribonuclease L-PSP
IOLKFBCL_02136	9.16e-151	-	-	-	S	-	-	-	CYTH
IOLKFBCL_02137	1.7e-213	ybbN	-	-	O	ko:K05838	-	ko00000,ko03110	Tetratricopeptide repeat
IOLKFBCL_02138	1.44e-231	-	-	-	-	-	-	-	-
IOLKFBCL_02139	3.71e-240	-	-	-	-	-	-	-	-
IOLKFBCL_02140	1.14e-205	-	5.2.1.8	-	M	ko:K01802	-	ko00000,ko01000	FKBP-type peptidyl-prolyl cis-trans isomerase
IOLKFBCL_02141	1.27e-174	nucS	-	-	L	ko:K07503	-	ko00000,ko01000	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
IOLKFBCL_02142	2.55e-65	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
IOLKFBCL_02143	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IOLKFBCL_02144	3.68e-204	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
IOLKFBCL_02145	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
IOLKFBCL_02146	6.56e-188	atpH	-	-	C	ko:K02109,ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IOLKFBCL_02147	1.74e-101	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
IOLKFBCL_02148	4.22e-41	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IOLKFBCL_02149	7.14e-188	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
IOLKFBCL_02150	5.46e-261	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IOLKFBCL_02151	3.43e-29	-	-	-	S	ko:K09803	-	ko00000	Ribonuclease toxin, BrnT, of type II toxin-antitoxin system
IOLKFBCL_02152	7.25e-19	-	-	-	-	-	-	-	-
IOLKFBCL_02155	2.34e-31	-	-	-	G	-	-	-	beta-galactosidase
IOLKFBCL_02157	1.21e-22	-	-	-	L	-	-	-	Transposase DDE domain
IOLKFBCL_02158	1.43e-96	-	-	-	S	ko:K06889	-	ko00000	Psort location Cytoplasmic, score 8.87
IOLKFBCL_02159	0.0	-	-	-	K	-	-	-	RNA polymerase II activating transcription factor binding
IOLKFBCL_02160	0.0	glgE	2.4.99.16	GH13	G	ko:K16147	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB
IOLKFBCL_02161	9.28e-118	ppa	3.6.1.1	-	C	ko:K01507	ko00190,map00190	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
IOLKFBCL_02162	1.93e-126	mntP	-	-	P	-	-	-	Probably functions as a manganese efflux pump
IOLKFBCL_02163	4.85e-120	-	-	-	-	-	-	-	-
IOLKFBCL_02164	5.65e-177	glnR	-	-	KT	-	-	-	Transcriptional regulatory protein, C terminal
IOLKFBCL_02165	2.81e-164	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IOLKFBCL_02166	0.0	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
IOLKFBCL_02167	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
IOLKFBCL_02168	0.0	-	-	-	S	-	-	-	domain protein
IOLKFBCL_02169	6.34e-81	tyrA	5.4.99.5	-	E	ko:K04092	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Chorismate mutase type II
IOLKFBCL_02170	0.0	rho	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
IOLKFBCL_02171	0.0	-	-	-	H	-	-	-	Flavin containing amine oxidoreductase
IOLKFBCL_02172	0.0	-	3.1.3.2, 3.6.1.27	-	I	ko:K09474,ko:K12685,ko:K19302	ko00550,ko00740,ko01100,ko02020,map00550,map00740,map01100,map02020	ko00000,ko00001,ko01000,ko01011,ko02000,ko02044	phosphatidate phosphatase activity
IOLKFBCL_02173	2.66e-68	-	-	-	S	-	-	-	Protein of unknown function (DUF2469)
IOLKFBCL_02174	6.53e-249	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
IOLKFBCL_02175	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IOLKFBCL_02176	0.0	gatA	6.3.5.6, 6.3.5.7	-	F	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
IOLKFBCL_02177	1.47e-67	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IOLKFBCL_02178	4.69e-235	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
IOLKFBCL_02179	8.81e-204	trmH	2.1.1.34	-	J	ko:K00556	-	ko00000,ko01000,ko03016	RNA methyltransferase TrmH family
IOLKFBCL_02180	4.22e-127	pyrE1	-	-	F	-	-	-	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
IOLKFBCL_02181	1.29e-279	rmuC	-	-	S	ko:K09760	-	ko00000	RmuC family
IOLKFBCL_02182	5.5e-56	csoR	-	-	S	ko:K21600	-	ko00000,ko03000	Metal-sensitive transcriptional repressor
IOLKFBCL_02183	0.0	-	3.6.3.4, 3.6.3.54	-	P	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	E1-E2 ATPase
IOLKFBCL_02184	2.03e-165	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
IOLKFBCL_02185	3.79e-09	-	-	-	L	-	-	-	Single-strand binding protein family
IOLKFBCL_02186	4.61e-94	-	3.2.1.51	GH29	G	ko:K01206	ko00511,map00511	ko00000,ko00001,ko01000,ko04147	Alpha-L-fucosidase
IOLKFBCL_02187	5.18e-218	-	-	-	S	-	-	-	Protein conserved in bacteria
IOLKFBCL_02188	0.0	-	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
IOLKFBCL_02189	1.23e-228	oppB1	-	-	EP	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOLKFBCL_02190	7.07e-226	oppC	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	N-terminal TM domain of oligopeptide transport permease C
IOLKFBCL_02191	0.0	oppD	-	-	P	ko:K02031,ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
IOLKFBCL_02192	0.0	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
IOLKFBCL_02194	0.0	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
IOLKFBCL_02195	0.0	-	-	-	S	ko:K07133	-	ko00000	AAA domain
IOLKFBCL_02196	0.0	-	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	Beta-galactosidase trimerisation domain
IOLKFBCL_02197	5.34e-245	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
IOLKFBCL_02198	4.55e-305	-	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
IOLKFBCL_02199	9.38e-229	-	-	-	U	ko:K02025,ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOLKFBCL_02200	2.58e-196	-	-	-	U	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOLKFBCL_02201	6.08e-247	-	-	-	G	-	-	-	Glycosyl hydrolases family 43
IOLKFBCL_02202	0.0	-	-	-	S	ko:K07133	-	ko00000	Domain of unknown function (DUF4143)
IOLKFBCL_02203	0.0	-	-	-	S	ko:K06921	-	ko00000	ATPase domain predominantly from Archaea
IOLKFBCL_02204	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
IOLKFBCL_02205	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
IOLKFBCL_02206	2.28e-250	-	-	-	S	-	-	-	Fic/DOC family
IOLKFBCL_02207	2.72e-237	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	TatD related DNase
IOLKFBCL_02208	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
IOLKFBCL_02209	1.2e-203	-	-	-	S	-	-	-	Glutamine amidotransferase domain
IOLKFBCL_02210	1.57e-173	-	-	-	T	ko:K06950	-	ko00000	HD domain
IOLKFBCL_02212	8.74e-243	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
IOLKFBCL_02213	1.17e-300	-	-	-	V	-	-	-	ABC transporter permease
IOLKFBCL_02214	0.0	-	-	-	S	-	-	-	Protein of unknown function (DUF4012)
IOLKFBCL_02215	4.18e-245	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
IOLKFBCL_02216	3.27e-256	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
IOLKFBCL_02217	0.0	glfT	2.4.1.288	GT2	S	ko:K16650	-	ko00000,ko01000,ko01003	Glycosyltransferase like family 2
IOLKFBCL_02218	2.37e-213	-	-	-	GM	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IOLKFBCL_02219	1.48e-131	tagG	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	Transport permease protein
IOLKFBCL_02220	9.53e-166	-	-	-	S	-	-	-	Glycosyltransferase, group 2 family protein
IOLKFBCL_02221	6.94e-229	-	-	-	M	-	-	-	Glycosyl transferases group 1
IOLKFBCL_02222	5.8e-70	-	-	-	S	-	-	-	Polysaccharide pyruvyl transferase
IOLKFBCL_02223	2.38e-215	-	-	-	M	-	-	-	Glycosyl transferase family 2
IOLKFBCL_02224	9.1e-234	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
IOLKFBCL_02225	3.47e-197	-	-	-	I	-	-	-	Acyltransferase family
IOLKFBCL_02226	1.43e-06	-	-	-	M	-	-	-	Glycosyl transferase family 2
IOLKFBCL_02227	4.13e-220	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
IOLKFBCL_02228	1.67e-154	-	-	-	G	ko:K02025,ko:K17330	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOLKFBCL_02229	9.45e-161	-	-	-	G	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOLKFBCL_02230	1.15e-231	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 5 (cellulase A) family
IOLKFBCL_02231	2.26e-283	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
IOLKFBCL_02232	9.89e-201	-	-	-	Q	-	-	-	Fumarylacetoacetate (FAA) hydrolase family
IOLKFBCL_02233	5.77e-94	-	2.3.1.57	-	K	ko:K03826,ko:K22441	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
IOLKFBCL_02234	0.0	clpB	-	-	O	ko:K03695,ko:K03696	ko01100,ko04213,map01100,map04213	ko00000,ko00001,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
IOLKFBCL_02235	2.77e-198	gluQ	6.1.1.17	-	J	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
IOLKFBCL_02236	3.69e-200	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Glycerophosphoryl diester phosphodiesterase family
IOLKFBCL_02237	2.38e-167	-	-	-	P	ko:K02025,ko:K05814	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOLKFBCL_02238	1.02e-162	-	-	-	G	ko:K02026,ko:K05815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOLKFBCL_02239	4.61e-262	-	-	-	G	ko:K02027,ko:K17329	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
IOLKFBCL_02240	1.47e-129	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Glycerophosphoryl diester phosphodiesterase family
IOLKFBCL_02241	1.31e-92	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
IOLKFBCL_02242	2.23e-149	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
IOLKFBCL_02243	2.48e-272	-	-	-	I	-	-	-	PAP2 superfamily
IOLKFBCL_02244	3.19e-53	-	-	-	L	ko:K07450	-	ko00000	Resolvase, N terminal domain
IOLKFBCL_02245	1.8e-168	-	-	-	L	ko:K07496	-	ko00000	Helix-turn-helix domain
IOLKFBCL_02246	9.87e-122	-	-	-	S	-	-	-	Protein of unknown function (DUF1706)
IOLKFBCL_02247	1.73e-161	-	-	-	P	ko:K10112,ko:K17240	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
IOLKFBCL_02248	8.36e-130	-	-	-	G	ko:K02025	-	ko00000,ko00002,ko02000	PFAM Binding-protein-dependent transport system inner membrane component
IOLKFBCL_02249	8.5e-128	-	-	-	P	ko:K02026,ko:K05815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOLKFBCL_02250	1.43e-144	-	-	-	S	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Metallo-beta-lactamase superfamily
IOLKFBCL_02251	1.21e-174	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Extracellular solute-binding protein
IOLKFBCL_02252	8.77e-38	-	-	-	S	-	-	-	phosphoglycolate phosphatase activity
IOLKFBCL_02253	2.27e-153	-	-	-	G	-	-	-	Glycosyl hydrolase family 20, domain 2
IOLKFBCL_02254	7.69e-60	-	-	-	G	-	-	-	Glycosyl hydrolase family 20, domain 2
IOLKFBCL_02255	1.04e-279	-	-	-	G	ko:K17318	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
IOLKFBCL_02256	6.43e-284	-	-	-	G	ko:K17318	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
IOLKFBCL_02257	7.8e-314	-	-	-	G	ko:K17318	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
IOLKFBCL_02258	5.84e-172	nanA	4.1.3.3, 4.3.3.7	-	EM	ko:K01639,ko:K01714	ko00261,ko00300,ko00520,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map00520,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Dihydrodipicolinate synthetase family
IOLKFBCL_02259	4.24e-149	-	3.2.1.18	GH33	G	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	ko00000,ko00001,ko01000,ko02042	BNR repeat-like domain
IOLKFBCL_02260	1.56e-295	-	-	-	G	ko:K17318	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
IOLKFBCL_02261	2.2e-192	-	-	-	G	ko:K17319	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOLKFBCL_02262	1.39e-194	-	-	-	G	ko:K17320	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOLKFBCL_02263	2.97e-123	-	-	-	S	-	-	-	Protein of unknown function, DUF624
IOLKFBCL_02264	5.38e-309	-	4.2.1.68	-	M	ko:K18334	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Enolase C-terminal domain-like
IOLKFBCL_02265	1.05e-181	-	1.1.1.100, 1.1.1.413	-	IQ	ko:K00059,ko:K18333,ko:K22322	ko00051,ko00061,ko00333,ko00780,ko01040,ko01100,ko01120,ko01130,ko01212,map00051,map00061,map00333,map00780,map01040,map01100,map01120,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	KR domain
IOLKFBCL_02266	2.56e-195	-	4.1.2.28	-	EM	ko:K22397	ko00040,map00040	ko00000,ko00001,ko01000	Dihydrodipicolinate synthetase family
IOLKFBCL_02267	1.8e-90	fucU	5.1.3.29	-	G	ko:K02431	-	ko00000,ko01000	RbsD / FucU transport protein family
IOLKFBCL_02268	0.0	-	3.2.1.51	GH29	G	ko:K01206	ko00511,map00511	ko00000,ko00001,ko01000,ko04147	Alpha-L-fucosidase
IOLKFBCL_02269	0.0	-	3.2.1.51	GH95	G	ko:K15923	ko00511,map00511	ko00000,ko00001,ko01000	Glycosyl hydrolase family 65, N-terminal domain
IOLKFBCL_02270	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
IOLKFBCL_02271	0.0	gph	-	-	G	ko:K16209	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
IOLKFBCL_02272	0.0	gph	-	-	G	ko:K16209	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
IOLKFBCL_02273	2.33e-174	-	-	-	-	-	-	-	-
IOLKFBCL_02274	1.53e-288	mutT	3.6.1.55	-	LT	ko:K03574	-	ko00000,ko01000,ko03400	Phosphoglycerate mutase family
IOLKFBCL_02275	0.0	ppk	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
IOLKFBCL_02276	5.29e-307	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
IOLKFBCL_02277	5.17e-179	ltbR	-	-	K	-	-	-	Transcriptional regulator, IclR family, C-terminal domain protein
IOLKFBCL_02278	0.0	leuC	4.2.1.33, 4.2.1.35	-	E	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
IOLKFBCL_02279	2.22e-169	leuD	4.2.1.33, 4.2.1.35	-	E	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
IOLKFBCL_02280	1.4e-264	pyr	1.3.98.1	-	F	ko:K00226	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Dihydroorotate dehydrogenase
IOLKFBCL_02281	0.0	nox	-	-	C	-	-	-	Pyridine nucleotide-disulphide oxidoreductase
IOLKFBCL_02282	0.0	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IOLKFBCL_02283	4.96e-310	-	4.4.1.8	-	E	ko:K00842,ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I II
IOLKFBCL_02284	2.18e-218	-	-	-	K	-	-	-	LysR substrate binding domain protein
IOLKFBCL_02285	3.57e-179	-	-	-	G	-	-	-	Transmembrane secretion effector
IOLKFBCL_02286	2.83e-154	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
IOLKFBCL_02287	1.73e-238	bglA	3.2.1.21	-	G	ko:K05350	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Glycosyl hydrolase family 1
IOLKFBCL_02288	0.0	-	3.2.1.25	-	G	ko:K01192	ko00511,ko04142,map00511,map04142	ko00000,ko00001,ko01000	beta-mannosidase
IOLKFBCL_02289	2.58e-155	-	-	-	P	ko:K02026,ko:K10242	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOLKFBCL_02290	9.88e-171	-	-	-	P	ko:K10189,ko:K10241	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOLKFBCL_02291	1.4e-205	-	-	-	G	ko:K10240	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
IOLKFBCL_02292	2.46e-138	-	-	-	K	ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
IOLKFBCL_02293	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
IOLKFBCL_02294	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
IOLKFBCL_02295	1.9e-295	hom	1.1.1.3, 2.7.2.4	-	E	ko:K00003,ko:K12524	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Homoserine dehydrogenase
IOLKFBCL_02296	3.57e-261	thrB	2.7.1.39	-	E	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
IOLKFBCL_02297	0.0	maf	-	-	DF	ko:K06287	-	ko00000	Maf-like protein
IOLKFBCL_02298	3.14e-11	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
IOLKFBCL_02299	2.92e-23	-	-	-	S	-	-	-	Protein of unknown function (DUF1778)
IOLKFBCL_02301	2.74e-166	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
IOLKFBCL_02302	0.0	-	-	-	V	-	-	-	Efflux ABC transporter, permease protein
IOLKFBCL_02303	2.48e-231	-	-	-	K	ko:K02529	-	ko00000,ko03000	Bacterial regulatory proteins, lacI family
IOLKFBCL_02304	6.85e-313	-	4.2.1.68	-	M	ko:K18334	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Enolase C-terminal domain-like
IOLKFBCL_02305	2.47e-180	-	1.1.1.100, 1.1.1.413	-	IQ	ko:K00059,ko:K18333,ko:K22322	ko00051,ko00061,ko00333,ko00780,ko01040,ko01100,ko01120,ko01130,ko01212,map00051,map00061,map00333,map00780,map01040,map01100,map01120,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	KR domain
IOLKFBCL_02306	1.47e-262	fucP	-	-	G	ko:K02429	-	ko00000,ko02000	Major Facilitator Superfamily
IOLKFBCL_02307	1.91e-189	-	-	-	S	ko:K07046	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Amidohydrolase
IOLKFBCL_02308	9.59e-101	fucU	5.1.3.29	-	G	ko:K02431	-	ko00000,ko01000	RbsD / FucU transport protein family
IOLKFBCL_02309	7.19e-210	-	-	-	S	ko:K07088	-	ko00000	Transporter, auxin efflux carrier (AEC) family protein
IOLKFBCL_02310	6.43e-288	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Peptidase dimerisation domain
IOLKFBCL_02311	0.0	rne	3.1.26.12	-	J	ko:K08300,ko:K08301	ko03018,map03018	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	Ribonuclease E/G family
IOLKFBCL_02312	4.13e-62	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
IOLKFBCL_02313	3.99e-53	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal L27 protein
IOLKFBCL_02314	0.0	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
IOLKFBCL_02315	5.06e-260	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IOLKFBCL_02316	3.78e-290	aspC	2.6.1.1, 2.6.1.2, 2.6.1.66	-	E	ko:K00812,ko:K14260	ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	DegT/DnrJ/EryC1/StrS aminotransferase family
IOLKFBCL_02318	1.95e-41	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
IOLKFBCL_02319	2.53e-190	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
IOLKFBCL_02320	4.11e-95	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
IOLKFBCL_02321	1.75e-159	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release